SMD44_RS30850 0e48c6243d813d76d046bbe73a4459bf 175 Gene3D G3DSA:3.30.300.70 1 82 1.0E-24 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SMD44_RS30850 0e48c6243d813d76d046bbe73a4459bf 175 Pfam PF02576 RimP N-terminal domain 12 85 9.0E-23 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SMD44_RS30850 0e48c6243d813d76d046bbe73a4459bf 175 Pfam PF17384 RimP C-terminal SH3 domain 88 155 1.5E-15 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SMD44_RS30850 0e48c6243d813d76d046bbe73a4459bf 175 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 155 21.799 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 SMD44_RS30850 0e48c6243d813d76d046bbe73a4459bf 175 SUPERFAMILY SSF74942 86 155 6.93E-5 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SMD44_RS30850 0e48c6243d813d76d046bbe73a4459bf 175 SUPERFAMILY SSF75420 3 85 1.31E-19 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SMD44_RS30850 0e48c6243d813d76d046bbe73a4459bf 175 Gene3D G3DSA:2.30.30.180 89 153 8.6E-5 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 Gene3D G3DSA:3.40.50.2300 1 147 2.5E-35 T 28-03-2018 SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 SMART SM00448 4 143 2.4E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 196 9.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 212 224 9.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 212 9.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 Gene3D G3DSA:1.10.10.10 148 246 6.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 SUPERFAMILY SSF46894 172 241 4.08E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 SMART SM00421 179 236 2.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 Pfam PF00196 Bacterial regulatory proteins, luxR family 181 236 8.3E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 SUPERFAMILY SSF52172 4 159 7.03E-15 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS16995 482dcbde3fda6bff48cf106955202fd8 258 Pfam PF00072 Response regulator receiver domain 6 64 4.5E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19385 4e4b80d2ae3857cb2f10d591d9fd8885 359 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 85 351 1.0E-85 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 SMD44_RS19385 4e4b80d2ae3857cb2f10d591d9fd8885 359 SUPERFAMILY SSF161098 91 346 3.53E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS19385 4e4b80d2ae3857cb2f10d591d9fd8885 359 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 156 357 4.9E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS19385 4e4b80d2ae3857cb2f10d591d9fd8885 359 Gene3D G3DSA:1.10.3720.10 85 358 3.0E-41 T 28-03-2018 SMD44_RS18445 464d475d6477a8d81d842d8d30cf33fe 258 SMART SM00530 5 60 3.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS18445 464d475d6477a8d81d842d8d30cf33fe 258 SUPERFAMILY SSF47413 1 47 4.5E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS18445 464d475d6477a8d81d842d8d30cf33fe 258 Pfam PF13560 Helix-turn-helix domain 2 61 4.1E-10 T 28-03-2018 SMD44_RS18445 464d475d6477a8d81d842d8d30cf33fe 258 Gene3D G3DSA:1.10.3100.10 1 136 3.5E-12 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 Pfam PF03949 Malic enzyme, NAD binding domain 240 461 1.1E-20 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 2.7E-30 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 SMART SM00919 238 465 1.1E-108 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 SUPERFAMILY SSF51735 238 471 2.12E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 Gene3D G3DSA:3.40.50.720 236 475 3.4E-68 T 28-03-2018 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 Gene3D G3DSA:3.40.50.10380 89 235 7.5E-39 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 SMART SM01274 93 226 5.9E-85 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 Gene3D G3DSA:3.30.70.260 11 88 8.8E-5 T 28-03-2018 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 SUPERFAMILY SSF53223 87 236 1.08E-56 T 28-03-2018 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 PRINTS PR00072 Malic enzyme signature 358 374 9.1E-12 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 PRINTS PR00072 Malic enzyme signature 265 281 9.1E-12 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 PRINTS PR00072 Malic enzyme signature 155 177 9.1E-12 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 PRINTS PR00072 Malic enzyme signature 234 250 9.1E-12 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMD44_RS15935 a2ab07b686fa535e5a5941a85e564030 476 PIRSF PIRSF000106 68 475 4.0E-81 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMD44_RS06605 c6fa0cd18f780720fd13a8c27f53b210 210 Gene3D G3DSA:1.10.1660.10 41 194 4.5E-15 T 28-03-2018 SMD44_RS06605 c6fa0cd18f780720fd13a8c27f53b210 210 SMART SM00422 52 124 1.4E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS06605 c6fa0cd18f780720fd13a8c27f53b210 210 SUPERFAMILY SSF46955 56 140 3.25E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS06605 c6fa0cd18f780720fd13a8c27f53b210 210 Pfam PF13411 MerR HTH family regulatory protein 56 122 1.5E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS25550 13e903e0ca9abdb485253b196dcbb6b3 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 6.2E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD44_RS25550 13e903e0ca9abdb485253b196dcbb6b3 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 6.5E-56 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 SMD44_RS25550 13e903e0ca9abdb485253b196dcbb6b3 122 SMART SM01374 1 122 1.4E-85 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD44_RS25550 13e903e0ca9abdb485253b196dcbb6b3 122 Gene3D G3DSA:2.40.150.20 1 122 1.1E-51 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD44_RS25550 13e903e0ca9abdb485253b196dcbb6b3 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25550 13e903e0ca9abdb485253b196dcbb6b3 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.306 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD44_RS25550 13e903e0ca9abdb485253b196dcbb6b3 122 SUPERFAMILY SSF50193 2 122 3.53E-49 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD44_RS42085 d7e82b1c21fa37c94b5509b8f62f6312 91 SUPERFAMILY SSF141694 6 88 8.63E-26 T 28-03-2018 SMD44_RS42085 d7e82b1c21fa37c94b5509b8f62f6312 91 Gene3D G3DSA:2.40.30.100 6 87 7.1E-26 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 SMD44_RS42085 d7e82b1c21fa37c94b5509b8f62f6312 91 Pfam PF08922 Domain of unknown function (DUF1905) 8 86 5.3E-24 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 Gene3D G3DSA:1.10.1660.10 151 209 8.0E-18 T 28-03-2018 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 SUPERFAMILY SSF46955 17 117 3.48E-11 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 SMART SM00422 155 224 4.9E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 SMART SM00422 13 81 0.0022 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 Gene3D G3DSA:1.10.1660.10 8 121 6.2E-14 T 28-03-2018 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 SUPERFAMILY SSF46955 155 263 8.06E-20 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 Pfam PF13411 MerR HTH family regulatory protein 156 223 3.4E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 Gene3D G3DSA:1.10.1660.10 210 278 8.8E-6 T 28-03-2018 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 Pfam PF00376 MerR family regulatory protein 17 51 1.5E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 167 180 9.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 156 167 9.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS14850 cc20f2fd87af3ac73fa6c535bcf8feff 281 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 191 211 9.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS40440 a9aeda2632bee0b7e56fdcf5cad0536b 495 Gene3D G3DSA:1.20.1250.20 13 207 7.7E-27 T 28-03-2018 SMD44_RS40440 a9aeda2632bee0b7e56fdcf5cad0536b 495 Gene3D G3DSA:1.20.1250.20 257 488 2.1E-24 T 28-03-2018 SMD44_RS40440 a9aeda2632bee0b7e56fdcf5cad0536b 495 SUPERFAMILY SSF103473 18 208 1.23E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS40440 a9aeda2632bee0b7e56fdcf5cad0536b 495 SUPERFAMILY SSF103473 254 471 1.23E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS40440 a9aeda2632bee0b7e56fdcf5cad0536b 495 Pfam PF07690 Major Facilitator Superfamily 23 420 2.3E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS32895 b051de80e648990794340b01fdc67205 251 Gene3D G3DSA:2.60.120.10 4 213 1.2E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS32895 b051de80e648990794340b01fdc67205 251 SUPERFAMILY SSF51182 41 208 4.79E-11 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS14010 35101e69f53ad00a9012601794e1431b 454 Pfam PF13091 PLD-like domain 91 230 1.3E-11 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SMD44_RS14010 35101e69f53ad00a9012601794e1431b 454 Pfam PF13091 PLD-like domain 285 423 7.6E-13 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SMD44_RS14010 35101e69f53ad00a9012601794e1431b 454 Gene3D G3DSA:3.30.870.10 66 268 1.7E-12 T 28-03-2018 SMD44_RS14010 35101e69f53ad00a9012601794e1431b 454 SUPERFAMILY SSF56024 96 161 1.03E-13 T 28-03-2018 SMD44_RS14010 35101e69f53ad00a9012601794e1431b 454 SUPERFAMILY SSF56024 357 432 1.03E-13 T 28-03-2018 SMD44_RS14010 35101e69f53ad00a9012601794e1431b 454 Gene3D G3DSA:3.30.870.10 269 432 3.7E-12 T 28-03-2018 SMD44_RS01210 2fa147f4b59269fe83b0bc054a3baff0 405 Gene3D G3DSA:1.20.1250.20 211 404 3.6E-12 T 28-03-2018 SMD44_RS01210 2fa147f4b59269fe83b0bc054a3baff0 405 Gene3D G3DSA:1.20.1250.20 16 207 4.3E-22 T 28-03-2018 SMD44_RS01210 2fa147f4b59269fe83b0bc054a3baff0 405 Pfam PF07690 Major Facilitator Superfamily 28 244 1.5E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS01210 2fa147f4b59269fe83b0bc054a3baff0 405 SUPERFAMILY SSF103473 14 402 5.89E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS36975 480852d49e8bf923d32f08355405c69a 575 SUPERFAMILY SSF51905 37 409 2.33E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36975 480852d49e8bf923d32f08355405c69a 575 SUPERFAMILY SSF51905 527 560 2.33E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36975 480852d49e8bf923d32f08355405c69a 575 Pfam PF01593 Flavin containing amine oxidoreductase 68 556 6.9E-26 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS36975 480852d49e8bf923d32f08355405c69a 575 Gene3D G3DSA:3.90.660.10 352 521 9.0E-18 T 28-03-2018 SMD44_RS36975 480852d49e8bf923d32f08355405c69a 575 Gene3D G3DSA:3.50.50.60 2 351 3.6E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36975 480852d49e8bf923d32f08355405c69a 575 SUPERFAMILY SSF54373 394 513 1.24E-10 T 28-03-2018 SMD44_RS10405 247b77c5ffca14791ca796d7379b00f1 326 SUPERFAMILY SSF56300 86 316 2.17E-45 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS10405 247b77c5ffca14791ca796d7379b00f1 326 Gene3D G3DSA:3.60.21.10 61 324 9.2E-40 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS10405 247b77c5ffca14791ca796d7379b00f1 326 Pfam PF00149 Calcineurin-like phosphoesterase 82 246 2.0E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS02950 e378a1124b783857b591797806fe687a 56 SUPERFAMILY SSF57829 1 38 2.99E-9 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMD44_RS02950 e378a1124b783857b591797806fe687a 56 Pfam PF01783 Ribosomal L32p protein family 2 45 6.2E-13 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS02950 e378a1124b783857b591797806fe687a 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 40 4.9E-12 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS02950 e378a1124b783857b591797806fe687a 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 13.497 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 190 416 6.8E-26 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 SUPERFAMILY SSF49899 535 732 9.4E-19 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 Gene3D G3DSA:3.20.20.80 188 521 1.6E-48 T 28-03-2018 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 33 180 2.8E-11 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 PRINTS PR00738 Glycosyl hydrolase family 20 signature 181 198 2.7E-13 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 PRINTS PR00738 Glycosyl hydrolase family 20 signature 145 165 2.7E-13 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 PRINTS PR00738 Glycosyl hydrolase family 20 signature 259 276 2.7E-13 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 PRINTS PR00738 Glycosyl hydrolase family 20 signature 332 345 2.7E-13 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 PRINTS PR00738 Glycosyl hydrolase family 20 signature 210 231 2.7E-13 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 Gene3D G3DSA:2.60.120.200 527 732 5.0E-18 T 28-03-2018 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 Gene3D G3DSA:3.30.379.10 27 187 6.4E-15 T 28-03-2018 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 609 730 9.5E-8 T 28-03-2018 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 SUPERFAMILY SSF55545 32 178 8.77E-10 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS11595 67b594d816ec1f77341518a8aa67bf3b 733 SUPERFAMILY SSF51445 189 507 1.31E-45 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS43010 b2d6c3f76dea91e90b62687957ad47d7 138 Gene3D G3DSA:3.40.630.30 10 133 1.9E-4 T 28-03-2018 SMD44_RS02740 99c6dcd8cb27cf78b25b9220fb1dd634 340 SUPERFAMILY SSF161098 93 324 1.96E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02740 99c6dcd8cb27cf78b25b9220fb1dd634 340 Gene3D G3DSA:1.10.3720.10 45 338 1.4E-46 T 28-03-2018 SMD44_RS02740 99c6dcd8cb27cf78b25b9220fb1dd634 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 333 9.3E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS11345 acae262e27d282bd20f9f0ceac14009c 220 Pfam PF00072 Response regulator receiver domain 4 114 8.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS11345 acae262e27d282bd20f9f0ceac14009c 220 Gene3D G3DSA:3.40.50.2300 2 121 4.1E-32 T 28-03-2018 SMD44_RS11345 acae262e27d282bd20f9f0ceac14009c 220 SMART SM00862 147 218 6.5E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS11345 acae262e27d282bd20f9f0ceac14009c 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 8.8E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS11345 acae262e27d282bd20f9f0ceac14009c 220 Gene3D G3DSA:1.10.10.10 122 219 1.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11345 acae262e27d282bd20f9f0ceac14009c 220 SUPERFAMILY SSF52172 3 176 5.62E-36 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS11345 acae262e27d282bd20f9f0ceac14009c 220 SMART SM00448 2 113 1.6E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 SMART SM00342 204 286 1.5E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 Pfam PF02311 AraC-like ligand binding domain 31 160 9.8E-25 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 SUPERFAMILY SSF51215 36 139 1.7E-19 T 28-03-2018 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 SUPERFAMILY SSF46689 192 237 2.87E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 Gene3D G3DSA:2.60.120.280 35 181 2.7E-11 T 28-03-2018 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 Gene3D G3DSA:1.10.10.60 246 297 1.9E-13 T 28-03-2018 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 Gene3D G3DSA:1.10.10.60 190 245 6.2E-14 T 28-03-2018 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 Pfam PF12833 Helix-turn-helix domain 210 287 1.2E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS12200 1ae899cc3e1f424997b6ea4c00b8e0fc 301 SUPERFAMILY SSF46689 241 290 7.17E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS28000 5780b41de8a3099b2990b8703b76826e 332 SUPERFAMILY SSF161098 108 298 1.83E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS28000 5780b41de8a3099b2990b8703b76826e 332 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 59 2.8E-8 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS28000 5780b41de8a3099b2990b8703b76826e 332 Gene3D G3DSA:1.10.3720.10 25 306 6.3E-39 T 28-03-2018 SMD44_RS28000 5780b41de8a3099b2990b8703b76826e 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 131 316 2.1E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 Gene3D G3DSA:3.20.20.80 5 479 2.4E-162 T 28-03-2018 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 12 26 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 377 385 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 Pfam PF00232 Glycosyl hydrolase family 1 7 470 3.4E-149 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 398 409 3.4E-23 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 377 385 3.4E-23 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 298 312 3.4E-23 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 419 436 3.4E-23 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 443 455 3.4E-23 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 TIGRFAM TIGR03356 BGL: beta-galactosidase 8 465 1.4E-175 T 28-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 SMD44_RS15065 b0ce1b806b775f534978ffab848d6ade 479 SUPERFAMILY SSF51445 7 473 2.05E-157 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS32230 f1ace7a9523a9949dec02694b1690331 130 SUPERFAMILY SSF54593 4 124 1.79E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS32230 f1ace7a9523a9949dec02694b1690331 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 1.8E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS32230 f1ace7a9523a9949dec02694b1690331 130 Gene3D G3DSA:3.10.180.10 2 126 2.9E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS20890 35933d3a8e59a8cb6a3161754a68a052 382 Gene3D G3DSA:3.40.640.10 12 256 4.5E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS20890 35933d3a8e59a8cb6a3161754a68a052 382 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 198 212 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMD44_RS20890 35933d3a8e59a8cb6a3161754a68a052 382 Gene3D G3DSA:3.90.1150.10 257 382 6.1E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS20890 35933d3a8e59a8cb6a3161754a68a052 382 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 43 377 1.3E-79 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMD44_RS20890 35933d3a8e59a8cb6a3161754a68a052 382 SUPERFAMILY SSF53383 44 379 7.51E-81 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS20890 35933d3a8e59a8cb6a3161754a68a052 382 PIRSF PIRSF001434 3 381 1.5E-102 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 441 763 1.8E-145 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 PIRSF PIRSF000382 9 772 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 323 5.5E-115 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 16 767 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 768 35.102 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 SUPERFAMILY SSF51726 12 404 7.72E-104 T 28-03-2018 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 Gene3D G3DSA:3.20.20.210 400 769 1.0E-124 T 28-03-2018 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 Gene3D G3DSA:3.20.20.210 10 399 8.4E-137 T 28-03-2018 SMD44_RS01055 4421ba828f5bef32d52f919fff855e85 772 SUPERFAMILY SSF51726 406 767 1.44E-112 T 28-03-2018 SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 SMART SM00420 9 61 6.4E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 Pfam PF00455 DeoR C terminal sensor domain 78 234 4.1E-43 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 SUPERFAMILY SSF100950 77 238 2.69E-23 T 28-03-2018 SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 SUPERFAMILY SSF46785 7 71 5.83E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 Pfam PF08220 DeoR-like helix-turn-helix domain 9 61 3.1E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 2.3E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 2.3E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 Gene3D G3DSA:3.40.50.1360 68 241 6.1E-32 T 28-03-2018 SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 SMART SM01134 76 237 3.4E-54 T 28-03-2018 SMD44_RS09840 7f6ac5cb0ca4ba385a1dfa2545d033b4 256 Gene3D G3DSA:1.10.10.10 4 65 7.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01340 9ba7ace1829206171e0e4af62465c331 576 SUPERFAMILY SSF101473 366 497 1.12E-26 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS01340 9ba7ace1829206171e0e4af62465c331 576 Pfam PF02734 DAK2 domain 388 498 2.3E-23 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS01340 9ba7ace1829206171e0e4af62465c331 576 Pfam PF02733 Dak1 domain 16 325 3.2E-100 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS01340 9ba7ace1829206171e0e4af62465c331 576 Gene3D G3DSA:3.40.50.10440 11 183 1.1E-56 T 28-03-2018 SMD44_RS01340 9ba7ace1829206171e0e4af62465c331 576 SMART SM01120 387 545 3.9E-9 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS01340 9ba7ace1829206171e0e4af62465c331 576 Gene3D G3DSA:3.30.1180.20 184 333 6.0E-34 T 28-03-2018 SMD44_RS01340 9ba7ace1829206171e0e4af62465c331 576 SUPERFAMILY SSF82549 11 326 2.35E-93 T 28-03-2018 SMD44_RS14295 4223833e46640692966433cb7593161e 1109 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 962 1024 1.2E-7 T 28-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial SMD44_RS14295 4223833e46640692966433cb7593161e 1109 Pfam PF00082 Subtilase family 208 644 9.1E-57 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS14295 4223833e46640692966433cb7593161e 1109 Gene3D G3DSA:2.60.120.380 945 1041 7.2E-9 T 28-03-2018 SMD44_RS14295 4223833e46640692966433cb7593161e 1109 Gene3D G3DSA:3.40.50.200 157 662 1.4E-67 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS14295 4223833e46640692966433cb7593161e 1109 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 213 224 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS14295 4223833e46640692966433cb7593161e 1109 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 591 601 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS14295 4223833e46640692966433cb7593161e 1109 PRINTS PR00723 Subtilisin serine protease family (S8) signature 208 227 2.2E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS14295 4223833e46640692966433cb7593161e 1109 PRINTS PR00723 Subtilisin serine protease family (S8) signature 393 406 2.2E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS14295 4223833e46640692966433cb7593161e 1109 PRINTS PR00723 Subtilisin serine protease family (S8) signature 590 606 2.2E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS14295 4223833e46640692966433cb7593161e 1109 SUPERFAMILY SSF52743 205 228 2.88E-54 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS14295 4223833e46640692966433cb7593161e 1109 SUPERFAMILY SSF52743 396 652 2.88E-54 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS08870 b6cb81d87faec9698bdfa156f3a66b85 353 SUPERFAMILY SSF46894 274 350 4.76E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS08870 b6cb81d87faec9698bdfa156f3a66b85 353 SMART SM00421 287 344 2.3E-4 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08870 b6cb81d87faec9698bdfa156f3a66b85 353 SUPERFAMILY SSF46785 8 74 3.46E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08870 b6cb81d87faec9698bdfa156f3a66b85 353 Gene3D G3DSA:1.10.10.10 279 349 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08870 b6cb81d87faec9698bdfa156f3a66b85 353 Gene3D G3DSA:1.10.10.10 3 131 6.4E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29995 b5003da3bbbf22c13d069ce1ed6611a4 336 Gene3D G3DSA:3.40.50.720 148 275 3.1E-25 T 28-03-2018 SMD44_RS29995 b5003da3bbbf22c13d069ce1ed6611a4 336 SUPERFAMILY SSF51735 123 299 6.85E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29995 b5003da3bbbf22c13d069ce1ed6611a4 336 Pfam PF16884 N-terminal domain of oxidoreductase 13 110 1.3E-24 T 28-03-2018 SMD44_RS29995 b5003da3bbbf22c13d069ce1ed6611a4 336 SMART SM00829 22 331 1.5E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS29995 b5003da3bbbf22c13d069ce1ed6611a4 336 Pfam PF00107 Zinc-binding dehydrogenase 157 287 1.1E-19 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS29995 b5003da3bbbf22c13d069ce1ed6611a4 336 Gene3D G3DSA:3.90.180.10 4 147 3.0E-30 T 28-03-2018 SMD44_RS29995 b5003da3bbbf22c13d069ce1ed6611a4 336 SUPERFAMILY SSF50129 8 143 1.48E-29 T 28-03-2018 IPR011032 GroES-like SMD44_RS27850 7cfe889d18ae5be0dad91fe403c6eed2 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 3.0E-29 T 28-03-2018 IPR021465 Protein of unknown function DUF3117 SMD44_RS10765 90043bbbef680586d3df6c4cb706a89b 271 SUPERFAMILY SSF51366 8 249 2.28E-78 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD44_RS10765 90043bbbef680586d3df6c4cb706a89b 271 Pfam PF00290 Tryptophan synthase alpha chain 13 265 2.6E-76 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD44_RS10765 90043bbbef680586d3df6c4cb706a89b 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 266 33.836 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD44_RS10765 90043bbbef680586d3df6c4cb706a89b 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD44_RS10765 90043bbbef680586d3df6c4cb706a89b 271 Gene3D G3DSA:3.20.20.70 6 271 2.8E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS10765 90043bbbef680586d3df6c4cb706a89b 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 263 1.7E-68 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD44_RS00720 92df878d26e74e1db49b435e0a46d13c 157 SUPERFAMILY SSF69118 23 152 2.62E-38 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS00720 92df878d26e74e1db49b435e0a46d13c 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 80 1.5E-20 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS00720 92df878d26e74e1db49b435e0a46d13c 157 Gene3D G3DSA:1.20.1290.10 1 155 3.9E-34 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS00720 92df878d26e74e1db49b435e0a46d13c 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 18 95 5.2E-21 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 Gene3D G3DSA:3.30.360.10 125 216 3.1E-33 T 28-03-2018 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 247 7.7E-27 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 Gene3D G3DSA:3.40.50.720 3 124 5.6E-27 T 28-03-2018 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 42 248 7.2E-51 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 28.919 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 PIRSF PIRSF000161 2 250 8.8E-60 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 SUPERFAMILY SSF55347 109 217 9.81E-38 T 28-03-2018 SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 SUPERFAMILY SSF51735 4 135 1.79E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31045 7a001eb481b179d446462f05c8e41325 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 9.7E-24 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS37210 67a4df746b2cd811621859e9a09fb593 292 SUPERFAMILY SSF51556 8 286 9.83E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS37210 67a4df746b2cd811621859e9a09fb593 292 Pfam PF04909 Amidohydrolase 10 286 7.3E-46 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS37210 67a4df746b2cd811621859e9a09fb593 292 Gene3D G3DSA:3.20.20.140 5 292 1.5E-41 T 28-03-2018 SMD44_RS07185 baf5109f351306a51141965a5307a936 135 SUPERFAMILY SSF54909 21 125 3.54E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS07185 baf5109f351306a51141965a5307a936 135 Pfam PF03795 YCII-related domain 15 109 9.9E-11 T 28-03-2018 IPR005545 YCII-related SMD44_RS07185 baf5109f351306a51141965a5307a936 135 Gene3D G3DSA:3.30.70.1060 1 132 1.3E-41 T 28-03-2018 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 103 5.7E-10 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 SUPERFAMILY SSF46946 121 208 1.15E-24 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 SMART SM00898 2 108 1.2E-19 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 ProSitePatterns PS01242 Zinc finger FPG-type signature. 246 270 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 208 2.0E-20 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 Gene3D G3DSA:3.20.190.10 1 121 1.6E-23 T 28-03-2018 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 SUPERFAMILY SSF81624 2 123 9.55E-23 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 Gene3D G3DSA:1.10.8.50 122 276 2.6E-47 T 28-03-2018 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 Pfam PF06827 Zinc finger found in FPG and IleRS 244 272 1.1E-5 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 SMART SM01232 122 217 2.6E-35 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD44_RS14215 759fff5aa8a2dea7815e9de18acfc54a 276 SUPERFAMILY SSF57716 223 271 1.1E-12 T 28-03-2018 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 109 4.9E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 219 368 4.1E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 Gene3D G3DSA:2.40.110.10 113 217 4.8E-37 T 28-03-2018 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 SUPERFAMILY SSF47203 217 368 1.77E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 114 204 5.2E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 116 128 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 Gene3D G3DSA:1.10.540.10 1 112 1.8E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 Gene3D G3DSA:1.20.140.10 218 373 2.1E-45 T 28-03-2018 SMD44_RS32175 6146d9e5f4c9d13c4122c31e6e9ccd0b 387 SUPERFAMILY SSF56645 3 230 3.01E-54 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 Gene3D G3DSA:3.50.50.60 1 115 7.5E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 Gene3D G3DSA:3.30.390.30 337 423 1.1E-22 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 1.1E-18 T 28-03-2018 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 1.1E-18 T 28-03-2018 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.1E-18 T 28-03-2018 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.1E-18 T 28-03-2018 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 312 2.2E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 SUPERFAMILY SSF55424 325 417 5.77E-22 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 Pfam PF14759 Reductase C-terminal 332 412 8.0E-24 T 28-03-2018 IPR028202 Reductase, C-terminal SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 SUPERFAMILY SSF51905 6 321 1.78E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 Gene3D G3DSA:3.50.50.60 116 251 3.5E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 Gene3D G3DSA:3.50.50.60 252 336 2.9E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 1.4E-22 T 28-03-2018 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 1.4E-22 T 28-03-2018 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.4E-22 T 28-03-2018 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 1.4E-22 T 28-03-2018 SMD44_RS38590 8889d92eafa200fc99b73b43f16b0cd6 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.4E-22 T 28-03-2018 SMD44_RS07390 041e185f2037d4d0eb1f2cf136f365f7 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 406 5.0E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07390 041e185f2037d4d0eb1f2cf136f365f7 433 SMART SM00387 314 407 7.6E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07390 041e185f2037d4d0eb1f2cf136f365f7 433 Pfam PF07730 Histidine kinase 215 280 1.2E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS07390 041e185f2037d4d0eb1f2cf136f365f7 433 PIRSF PIRSF037434 23 412 8.8E-75 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS SMD44_RS07390 041e185f2037d4d0eb1f2cf136f365f7 433 Gene3D G3DSA:3.30.565.10 285 413 8.2E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07390 041e185f2037d4d0eb1f2cf136f365f7 433 SUPERFAMILY SSF55874 288 405 9.43E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 Gene3D G3DSA:3.40.50.300 2 290 1.3E-54 T 28-03-2018 SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 SMART SM00382 384 547 8.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 SMART SM00382 43 247 2.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 Gene3D G3DSA:3.40.50.300 360 548 1.7E-32 T 28-03-2018 SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 ProSitePatterns PS00211 ABC transporters family signature. 174 188 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 SUPERFAMILY SSF52540 19 245 1.26E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 SUPERFAMILY SSF52540 375 537 9.02E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 Pfam PF00005 ABC transporter 380 503 4.3E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS41835 e4542a1f7df0213cd072c62c06cf9829 550 Pfam PF00005 ABC transporter 34 202 1.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 SUPERFAMILY SSF81891 174 485 4.32E-70 T 28-03-2018 SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 Pfam PF01743 Poly A polymerase head domain 46 176 3.3E-30 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 203 264 3.8E-21 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 TIGRFAM TIGR00277 HDIG: HDIG domain 275 352 6.7E-18 T 28-03-2018 IPR006675 HDIG domain SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 18 485 4.2E-244 T 28-03-2018 IPR014065 tRNA adenylyltransferase SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 Gene3D G3DSA:3.30.460.10 23 174 8.9E-43 T 28-03-2018 SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 Pfam PF01966 HD domain 278 378 1.0E-14 T 28-03-2018 IPR006674 HD domain SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 SMART SM00471 274 488 6.8E-5 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 Gene3D G3DSA:1.10.3090.10 175 484 7.4E-74 T 28-03-2018 SMD44_RS21035 f04851d784c4e54b59a979e811564faa 489 SUPERFAMILY SSF81301 26 173 1.2E-33 T 28-03-2018 SMD44_RS18860 415e75178bbffaab69b869d9ce1a5940 172 SMART SM00903 10 170 1.1E-49 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS18860 415e75178bbffaab69b869d9ce1a5940 172 SUPERFAMILY SSF50475 2 171 1.13E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS18860 415e75178bbffaab69b869d9ce1a5940 172 Gene3D G3DSA:2.30.110.10 1 172 5.1E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS18860 415e75178bbffaab69b869d9ce1a5940 172 Pfam PF01613 Flavin reductase like domain 10 171 1.9E-39 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 362 42.166 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 PIRSF PIRSF006641 1 362 3.0E-142 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 Gene3D G3DSA:3.40.50.300 2 80 6.6E-9 T 28-03-2018 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 Gene3D G3DSA:1.10.150.300 110 201 5.3E-22 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 362 1.7E-131 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 Pfam PF06071 Protein of unknown function (DUF933) 278 361 1.1E-38 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 SUPERFAMILY SSF81271 278 362 1.33E-34 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 Gene3D G3DSA:3.10.20.30 262 361 1.8E-42 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 Pfam PF01926 50S ribosome-binding GTPase 5 123 1.0E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS27565 b7d8555d6eca4d2b7ef961f85e3f1344 362 SUPERFAMILY SSF52540 3 300 3.27E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Gene3D G3DSA:3.40.50.620 441 528 5.3E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 PRINTS PR00986 Valyl-tRNA synthetase signature 50 61 6.1E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 PRINTS PR00986 Valyl-tRNA synthetase signature 451 472 6.1E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 PRINTS PR00986 Valyl-tRNA synthetase signature 357 370 6.1E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 PRINTS PR00986 Valyl-tRNA synthetase signature 482 500 6.1E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 PRINTS PR00986 Valyl-tRNA synthetase signature 242 259 6.1E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 SUPERFAMILY SSF50677 206 345 7.33E-53 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Hamap MF_02004 Valine--tRNA ligase [valS]. 16 872 15.166 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 SUPERFAMILY SSF47323 583 820 1.23E-48 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Gene3D G3DSA:3.90.740.10 244 440 1.6E-58 T 28-03-2018 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Gene3D G3DSA:3.40.50.620 37 230 7.0E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Pfam PF08264 Anticodon-binding domain of tRNA 613 754 5.7E-36 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Gene3D G3DSA:1.10.287.380 800 870 7.5E-21 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Gene3D G3DSA:1.10.730.10 529 749 7.9E-64 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 SUPERFAMILY SSF52374 352 581 4.02E-136 T 28-03-2018 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 SUPERFAMILY SSF52374 15 206 4.02E-136 T 28-03-2018 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 SUPERFAMILY SSF46589 807 871 6.8E-14 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 448 567 1.8E-44 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 436 2.2E-145 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 807 871 1.3E-16 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SMD44_RS14120 4968a9f21ef4017a047420e820196d7b 874 TIGRFAM TIGR00422 valS: valine--tRNA ligase 17 849 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Pfam PF13374 Tetratricopeptide repeat 515 539 0.014 T 28-03-2018 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Gene3D G3DSA:1.10.10.10 311 384 0.13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Gene3D G3DSA:1.10.10.10 267 310 0.092 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Gene3D G3DSA:1.10.150.200 559 596 2.3E-8 T 28-03-2018 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 SUPERFAMILY SSF48452 512 644 2.35E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Gene3D G3DSA:3.40.50.300 54 213 1.7E-14 T 28-03-2018 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 SMART SM00028 547 580 55.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 SMART SM00028 706 739 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 SMART SM00028 510 543 5.6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 SMART SM00028 587 620 390.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 PRINTS PR00364 Disease resistance protein signature 261 275 6.9E-9 T 28-03-2018 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 PRINTS PR00364 Disease resistance protein signature 86 101 6.9E-9 T 28-03-2018 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 PRINTS PR00364 Disease resistance protein signature 172 186 6.9E-9 T 28-03-2018 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Gene3D G3DSA:1.25.40.10 645 789 4.8E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Pfam PF13191 AAA ATPase domain 62 185 4.3E-10 T 28-03-2018 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Gene3D G3DSA:1.25.40.10 597 644 0.39 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Gene3D G3DSA:1.25.40.10 510 558 1.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 SUPERFAMILY SSF48452 649 781 9.05E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 SUPERFAMILY SSF52540 57 319 3.28E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13470 0ed90fa340eeebec795cff9ac61e8467 957 Pfam PF13424 Tetratricopeptide repeat 666 736 1.5E-8 T 28-03-2018 SMD44_RS12690 2107daf722343e3365a6e8bf4fa6a9e9 191 Pfam PF02342 TerD domain 3 187 2.5E-86 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS12690 2107daf722343e3365a6e8bf4fa6a9e9 191 Gene3D G3DSA:2.60.60.30 19 186 9.4E-69 T 28-03-2018 SMD44_RS06380 7eb379b6044ca4684d678188ce8bb451 180 SUPERFAMILY SSF55729 2 159 6.28E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS06380 7eb379b6044ca4684d678188ce8bb451 180 Gene3D G3DSA:3.40.630.30 1 161 4.0E-19 T 28-03-2018 SMD44_RS06380 7eb379b6044ca4684d678188ce8bb451 180 Pfam PF13527 Acetyltransferase (GNAT) domain 45 134 1.9E-13 T 28-03-2018 SMD44_RS16955 5c9dffcd574e4db3fb47b485316c8460 198 SUPERFAMILY SSF53178 8 197 2.35E-62 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD44_RS16955 5c9dffcd574e4db3fb47b485316c8460 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 120 130 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SMD44_RS16955 5c9dffcd574e4db3fb47b485316c8460 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 10 197 4.4E-52 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD44_RS16955 5c9dffcd574e4db3fb47b485316c8460 198 Gene3D G3DSA:3.40.50.1470 2 198 1.2E-67 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD44_RS16955 5c9dffcd574e4db3fb47b485316c8460 198 Pfam PF01195 Peptidyl-tRNA hydrolase 10 197 2.1E-51 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD44_RS16955 5c9dffcd574e4db3fb47b485316c8460 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 8 190 32.658 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD44_RS16955 5c9dffcd574e4db3fb47b485316c8460 198 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 21 34 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SMD44_RS28160 74edfbe41109a8e43bef9cac3e2a9b4d 490 Pfam PF10103 Zincin-like metallopeptidase 86 438 1.2E-126 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 SMD44_RS28160 74edfbe41109a8e43bef9cac3e2a9b4d 490 SUPERFAMILY SSF55486 85 440 1.46E-116 T 28-03-2018 SMD44_RS28160 74edfbe41109a8e43bef9cac3e2a9b4d 490 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 86 440 4.3E-123 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 SMD44_RS29930 805947a904f6b9bd934ed77b23231d2e 574 SUPERFAMILY SSF103473 265 436 2.75E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS29930 805947a904f6b9bd934ed77b23231d2e 574 SUPERFAMILY SSF103473 11 218 2.75E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS29930 805947a904f6b9bd934ed77b23231d2e 574 Gene3D G3DSA:1.20.1250.20 21 216 3.8E-27 T 28-03-2018 SMD44_RS29930 805947a904f6b9bd934ed77b23231d2e 574 Gene3D G3DSA:1.20.1250.20 277 506 6.1E-14 T 28-03-2018 SMD44_RS29930 805947a904f6b9bd934ed77b23231d2e 574 Pfam PF07690 Major Facilitator Superfamily 39 428 4.9E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS13870 ce3d63061c80e5a2362e7358c1d3527d 268 Pfam PF12836 Helix-hairpin-helix motif 205 266 2.9E-22 T 28-03-2018 SMD44_RS13870 ce3d63061c80e5a2362e7358c1d3527d 268 Pfam PF10531 SLBB domain 112 163 8.2E-9 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS13870 ce3d63061c80e5a2362e7358c1d3527d 268 Gene3D G3DSA:1.10.150.320 205 267 3.8E-20 T 28-03-2018 SMD44_RS13870 ce3d63061c80e5a2362e7358c1d3527d 268 Gene3D G3DSA:3.10.560.10 105 204 3.1E-8 T 28-03-2018 SMD44_RS13870 ce3d63061c80e5a2362e7358c1d3527d 268 SMART SM00278 246 265 270.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMD44_RS13870 ce3d63061c80e5a2362e7358c1d3527d 268 SMART SM00278 216 235 0.34 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMD44_RS13870 ce3d63061c80e5a2362e7358c1d3527d 268 SUPERFAMILY SSF47781 199 263 4.45E-26 T 28-03-2018 IPR010994 RuvA domain 2-like SMD44_RS34405 dae5a1d93770afe030434bdad89c2c6e 309 Gene3D G3DSA:1.10.10.60 257 309 7.8E-7 T 28-03-2018 SMD44_RS34405 dae5a1d93770afe030434bdad89c2c6e 309 Gene3D G3DSA:1.10.10.60 200 256 6.9E-10 T 28-03-2018 SMD44_RS34405 dae5a1d93770afe030434bdad89c2c6e 309 SUPERFAMILY SSF46689 207 255 2.24E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS34405 dae5a1d93770afe030434bdad89c2c6e 309 SMART SM00342 221 307 2.7E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS34405 dae5a1d93770afe030434bdad89c2c6e 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 258 303 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS34405 dae5a1d93770afe030434bdad89c2c6e 309 Pfam PF14525 AraC-binding-like domain 5 185 1.6E-32 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMD44_RS34405 dae5a1d93770afe030434bdad89c2c6e 309 Pfam PF12833 Helix-turn-helix domain 227 308 2.2E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS20070 02d473d525921470811a81fded1256b1 262 SUPERFAMILY SSF64288 71 260 2.04E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS20070 02d473d525921470811a81fded1256b1 262 Gene3D G3DSA:1.10.10.10 9 85 3.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20070 02d473d525921470811a81fded1256b1 262 Gene3D G3DSA:3.40.1410.10 89 257 1.4E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS20070 02d473d525921470811a81fded1256b1 262 SMART SM00866 115 254 1.8E-24 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS20070 02d473d525921470811a81fded1256b1 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 1.2E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS20070 02d473d525921470811a81fded1256b1 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 9.2E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS20070 02d473d525921470811a81fded1256b1 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 9.2E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS20070 02d473d525921470811a81fded1256b1 262 SMART SM00345 24 83 7.1E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS20070 02d473d525921470811a81fded1256b1 262 SUPERFAMILY SSF46785 13 95 2.03E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20070 02d473d525921470811a81fded1256b1 262 Pfam PF07702 UTRA domain 116 253 8.0E-30 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 384 517 2.7E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 SUPERFAMILY SSF48452 158 255 6.24E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 SUPERFAMILY SSF48452 12 46 6.24E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 PRINTS PR00819 CbxX/CfqX superfamily signature 420 434 1.8E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 PRINTS PR00819 CbxX/CfqX superfamily signature 467 479 1.8E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 PRINTS PR00819 CbxX/CfqX superfamily signature 488 505 1.8E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 PRINTS PR00819 CbxX/CfqX superfamily signature 565 577 1.8E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 PRINTS PR00819 CbxX/CfqX superfamily signature 382 397 1.8E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 PRINTS PR00819 CbxX/CfqX superfamily signature 505 524 1.8E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 PRINTS PR00819 CbxX/CfqX superfamily signature 434 453 1.8E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 PRINTS PR00819 CbxX/CfqX superfamily signature 342 356 1.8E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 Gene3D G3DSA:1.25.40.10 5 253 4.7E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 SUPERFAMILY SSF52540 343 586 3.37E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 SMART SM00382 379 520 1.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS06980 e9a3b64a2f96f22d829144d30d9e4c55 623 Gene3D G3DSA:3.40.50.300 330 517 3.5E-23 T 28-03-2018 SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 SUPERFAMILY SSF52317 3 198 8.02E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 Gene3D G3DSA:3.40.50.880 4 231 9.4E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 Pfam PF12833 Helix-turn-helix domain 241 319 1.6E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 SUPERFAMILY SSF46689 224 268 2.51E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 Gene3D G3DSA:1.10.10.60 273 328 8.8E-14 T 28-03-2018 SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 Pfam PF01965 DJ-1/PfpI family 62 180 2.3E-12 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 SMART SM00342 235 318 1.3E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 SUPERFAMILY SSF46689 272 322 2.82E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01105 479e0875cae450a8d484b273bea1f1c9 347 Gene3D G3DSA:1.10.10.60 232 272 2.6E-8 T 28-03-2018 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 Gene3D G3DSA:1.10.390.10 281 449 4.4E-45 T 28-03-2018 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 1.7E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 295 310 1.7E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 1.7E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 314 326 1.7E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 1.7E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 Pfam PF11838 ERAP1-like C-terminal domain 539 848 3.4E-60 T 28-03-2018 IPR024571 ERAP1-like C-terminal domain SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 SUPERFAMILY SSF55486 206 455 1.47E-74 T 28-03-2018 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 Gene3D G3DSA:2.60.40.1730 15 196 1.7E-32 T 28-03-2018 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 SUPERFAMILY SSF63737 5 195 4.05E-37 T 28-03-2018 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 854 0.0 T 28-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMD44_RS14405 268587c648ac094b33f57966f01cab32 857 Pfam PF01433 Peptidase family M1 domain 209 445 1.3E-61 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS01095 5da485a0c6ff0629aa929f56aecf1c73 156 PRINTS PR00502 NUDIX hydrolase family signature 31 45 5.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS01095 5da485a0c6ff0629aa929f56aecf1c73 156 PRINTS PR00502 NUDIX hydrolase family signature 45 60 5.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS01095 5da485a0c6ff0629aa929f56aecf1c73 156 Gene3D G3DSA:3.90.79.10 1 137 1.6E-26 T 28-03-2018 SMD44_RS01095 5da485a0c6ff0629aa929f56aecf1c73 156 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS01095 5da485a0c6ff0629aa929f56aecf1c73 156 SUPERFAMILY SSF55811 3 129 3.11E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS01095 5da485a0c6ff0629aa929f56aecf1c73 156 Pfam PF00293 NUDIX domain 4 121 2.5E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 SUPERFAMILY SSF49503 53 151 7.37E-12 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 Gene3D G3DSA:2.60.40.10 364 416 1.8E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 Gene3D G3DSA:2.60.40.10 270 337 2.6E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 Gene3D G3DSA:2.60.40.10 176 243 1.8E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 Gene3D G3DSA:2.60.40.1310 417 531 0.0012 T 28-03-2018 SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 Gene3D G3DSA:2.60.120.560 532 741 2.2E-37 T 28-03-2018 SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 Pfam PF06439 Domain of Unknown Function (DUF1080) 533 739 5.8E-30 T 28-03-2018 IPR010496 Domain of unknown function DUF1080 SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 Gene3D G3DSA:2.60.40.420 42 175 2.5E-6 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 SUPERFAMILY SSF81296 375 428 6.09E-5 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS35225 1a33ae0f9d95cb9d9c5c122dbdfdc1d9 741 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 130 145 - T 28-03-2018 IPR028871 Blue (type 1) copper protein, binding site SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1346 1648 2.5E-90 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.40.50.720 2340 2667 1.2E-61 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 978 994 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Pfam PF00155 Aminotransferase class I and II 1934 2276 3.6E-48 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.30.300.30 514 622 6.2E-13 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF52151 1342 1471 3.66E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF52151 1534 1624 3.66E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1073 1190 2.6E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.40.47.10 1080 1240 3.3E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF53383 1898 2282 8.16E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.40.50.980 18 229 3.0E-31 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.90.1150.10 2179 2290 9.9E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 827 1065 1.1E-86 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Pfam PF00550 Phosphopantetheine attachment site 735 800 2.2E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:2.30.38.10 418 513 1.4E-18 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SMART SM00825 Beta-ketoacyl synthase 829 1242 1.1E-199 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Pfam PF00501 AMP-binding enzyme 28 521 6.7E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.40.366.10 1337 1523 4.0E-55 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.40.47.10 827 1077 1.3E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:1.10.1200.10 1782 1894 3.4E-10 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:1.10.1200.10 727 826 3.1E-18 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.40.366.10 1524 1632 1.9E-20 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:1.10.1200.10 629 726 1.6E-6 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF47336 1787 1876 1.7E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 ProSitePatterns PS00455 Putative AMP-binding domain signature. 224 235 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF56801 16 398 2.09E-101 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF56801 428 625 2.09E-101 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF55048 1469 1533 4.32E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF47336 730 841 9.16E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF51735 2342 2596 3.92E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF51735 2624 2662 3.92E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.40.50.980 230 400 7.0E-33 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Pfam PF01370 NAD dependent epimerase/dehydratase family 2342 2565 1.9E-32 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1193 1307 4.2E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SMART SM00823 Phosphopantetheine attachment site 733 804 1.5E-15 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SMART SM00823 Phosphopantetheine attachment site 648 721 0.32 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SMART SM00823 Phosphopantetheine attachment site 1786 1860 0.012 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Pfam PF00698 Acyl transferase domain 1345 1625 1.0E-50 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF53901 1217 1239 2.03E-93 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SUPERFAMILY SSF53901 825 1186 2.03E-93 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 SMART SM01294 734 800 5.5E-5 T 28-03-2018 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 Gene3D G3DSA:3.40.640.10 1939 2178 1.3E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS36195 1a059fee6c25656505b012b53f531adb 2673 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 2132 2141 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD44_RS07755 36f6fd5e821ebf31027be14a197133d5 195 Gene3D G3DSA:2.30.110.10 1 140 4.1E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS07755 36f6fd5e821ebf31027be14a197133d5 195 SUPERFAMILY SSF50475 8 115 1.59E-10 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS07755 36f6fd5e821ebf31027be14a197133d5 195 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 102 1.8E-11 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS30755 18950279ce05fcd4e429d9a1c8ee9a5f 444 SUPERFAMILY SSF53383 36 443 1.58E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS30755 18950279ce05fcd4e429d9a1c8ee9a5f 444 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS30755 18950279ce05fcd4e429d9a1c8ee9a5f 444 PIRSF PIRSF000521 1 146 4.6E-8 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS30755 18950279ce05fcd4e429d9a1c8ee9a5f 444 PIRSF PIRSF000521 138 444 8.8E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS30755 18950279ce05fcd4e429d9a1c8ee9a5f 444 Gene3D G3DSA:3.40.640.10 73 320 2.2E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS30755 18950279ce05fcd4e429d9a1c8ee9a5f 444 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 25 441 2.2E-180 T 28-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 SMD44_RS30755 18950279ce05fcd4e429d9a1c8ee9a5f 444 Pfam PF00202 Aminotransferase class-III 38 440 4.1E-126 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS30755 18950279ce05fcd4e429d9a1c8ee9a5f 444 Gene3D G3DSA:3.90.1150.10 321 444 4.0E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS22405 0e47f5a66e4f89a4d78922e03858296c 191 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 33.605 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 SMD44_RS22405 0e47f5a66e4f89a4d78922e03858296c 191 SUPERFAMILY SSF51283 2 183 3.4E-56 T 28-03-2018 IPR029054 dUTPase-like SMD44_RS22405 0e47f5a66e4f89a4d78922e03858296c 191 Pfam PF00692 dUTPase 70 160 1.2E-9 T 28-03-2018 IPR029054 dUTPase-like SMD44_RS22405 0e47f5a66e4f89a4d78922e03858296c 191 Gene3D G3DSA:2.70.40.10 1 159 6.6E-47 T 28-03-2018 SMD44_RS22405 0e47f5a66e4f89a4d78922e03858296c 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 1.3E-63 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 SMD44_RS05675 5553b1f8cca77f123f127c54da88c079 220 Pfam PF10935 Protein of unknown function (DUF2637) 5 115 1.4E-16 T 28-03-2018 IPR021235 Protein of unknown function DUF2637 SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 Gene3D G3DSA:2.60.40.10 344 447 4.7E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 Gene3D G3DSA:2.60.40.10 151 245 2.7E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 SUPERFAMILY SSF49265 65 238 6.63E-14 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 Pfam PF00041 Fibronectin type III domain 348 435 4.7E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 SMART SM00060 153 230 4.8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 SMART SM00060 346 434 3.3E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 SMART SM00060 56 138 2.8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 SMART SM00060 249 332 37.0 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 Gene3D G3DSA:2.60.40.10 246 342 1.1E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 SUPERFAMILY SSF49265 243 342 1.1E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 Gene3D G3DSA:2.60.40.10 52 145 1.4E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS37785 d0aa3da57b5a80169ac6646f528961da 447 SUPERFAMILY SSF49265 343 444 5.78E-14 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS18520 5fb1f3864cba135c19b68a7fc043f6b6 448 SUPERFAMILY SSF103473 33 421 1.31E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS18520 5fb1f3864cba135c19b68a7fc043f6b6 448 Gene3D G3DSA:1.20.1250.20 20 230 1.8E-20 T 28-03-2018 SMD44_RS18520 5fb1f3864cba135c19b68a7fc043f6b6 448 Pfam PF05977 Transmembrane secretion effector 25 417 2.0E-54 T 28-03-2018 IPR010290 Transmembrane secretion effector SMD44_RS18520 5fb1f3864cba135c19b68a7fc043f6b6 448 Gene3D G3DSA:1.20.1250.20 231 421 2.4E-20 T 28-03-2018 SMD44_RS00725 289999b3f5cc35b70fe236d70d800e6e 152 Gene3D G3DSA:1.20.1290.10 1 152 6.0E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS00725 289999b3f5cc35b70fe236d70d800e6e 152 SUPERFAMILY SSF69118 11 146 2.28E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS00725 289999b3f5cc35b70fe236d70d800e6e 152 Pfam PF02627 Carboxymuconolactone decarboxylase family 13 95 5.7E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS00725 289999b3f5cc35b70fe236d70d800e6e 152 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 79 2.5E-10 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.6E-44 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 SUPERFAMILY SSF56235 1 224 7.38E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 538 3.4E-138 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 Gene3D G3DSA:3.40.50.620 225 595 3.6E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 PIRSF PIRSF001589 1 611 2.6E-135 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 SUPERFAMILY SSF52402 229 396 2.02E-60 T 28-03-2018 SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 SUPERFAMILY SSF52402 458 581 2.02E-60 T 28-03-2018 SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 Pfam PF00733 Asparagine synthase 240 589 4.4E-81 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD44_RS05525 fd8392c2ad511c1eea5af5972244989d 613 Gene3D G3DSA:3.60.20.10 1 224 3.2E-56 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS25895 9b93a55f8886e118ae38917f87b86b4c 100 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 28 98 1.4E-15 T 28-03-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal SMD44_RS25895 9b93a55f8886e118ae38917f87b86b4c 100 Gene3D G3DSA:1.20.59.10 12 99 8.6E-13 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS25895 9b93a55f8886e118ae38917f87b86b4c 100 SUPERFAMILY SSF48600 27 85 7.48E-10 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS25895 9b93a55f8886e118ae38917f87b86b4c 100 SMART SM00830 29 90 2.8E-4 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS25895 9b93a55f8886e118ae38917f87b86b4c 100 Pfam PF01817 Chorismate mutase type II 29 80 2.3E-7 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 SUPERFAMILY SSF51735 137 303 1.38E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 SMART SM01002 149 297 1.7E-82 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 1.1E-47 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 PIRSF PIRSF000183 1 371 3.5E-168 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 SUPERFAMILY SSF52283 305 360 2.13E-67 T 28-03-2018 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 SUPERFAMILY SSF52283 2 137 2.13E-67 T 28-03-2018 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 28-03-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 2.6E-80 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 Gene3D G3DSA:3.40.50.720 197 371 4.7E-46 T 28-03-2018 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 Gene3D G3DSA:3.40.50.720 1 177 2.1E-45 T 28-03-2018 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 370 5.9E-173 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 Gene3D G3DSA:3.50.50.60 178 196 1.6E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS09115 6b4c1a58e439649980b20cbfd1662025 371 SMART SM01003 4 137 7.2E-80 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SMD44_RS30860 dd358402ccbb283c2773ab43d6c6e5e5 99 Pfam PF04296 Protein of unknown function (DUF448) 13 82 1.8E-21 T 28-03-2018 IPR007393 Domain of unknown function DUF448 SMD44_RS30860 dd358402ccbb283c2773ab43d6c6e5e5 99 SUPERFAMILY SSF64376 9 88 1.09E-22 T 28-03-2018 IPR007393 Domain of unknown function DUF448 SMD44_RS30860 dd358402ccbb283c2773ab43d6c6e5e5 99 Gene3D G3DSA:3.30.1230.10 2 97 1.3E-25 T 28-03-2018 IPR007393 Domain of unknown function DUF448 SMD44_RS28520 72108407e43b88bce8a53ee2548b1162 316 Gene3D G3DSA:1.10.3720.10 34 290 4.3E-45 T 28-03-2018 SMD44_RS28520 72108407e43b88bce8a53ee2548b1162 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 281 5.6E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS28520 72108407e43b88bce8a53ee2548b1162 316 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 71 179 1.2E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD44_RS28520 72108407e43b88bce8a53ee2548b1162 316 SUPERFAMILY SSF161098 69 270 9.42E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 PIRSF PIRSF001554 1 379 2.5E-130 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 Pfam PF00549 CoA-ligase 254 369 1.9E-13 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 376 2.9E-119 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 SUPERFAMILY SSF56059 1 217 3.72E-61 T 28-03-2018 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 Pfam PF08442 ATP-grasp domain 2 190 2.9E-65 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 377 36.179 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 Gene3D G3DSA:3.30.470.20 88 221 1.5E-44 T 28-03-2018 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 SUPERFAMILY SSF52210 229 376 2.35E-43 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 247 271 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 Gene3D G3DSA:3.30.1490.20 21 87 3.6E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS34810 83f37d0e2689361f38f16515f4a825da 379 Gene3D G3DSA:3.40.50.261 230 376 2.0E-38 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS02425 3d0c73b8b6a035670afad1b8d560a6a5 246 SUPERFAMILY SSF53335 11 244 1.03E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS02425 3d0c73b8b6a035670afad1b8d560a6a5 246 Gene3D G3DSA:3.40.50.150 3 245 1.9E-27 T 28-03-2018 SMD44_RS02425 3d0c73b8b6a035670afad1b8d560a6a5 246 Pfam PF13649 Methyltransferase domain 46 138 2.6E-8 T 28-03-2018 SMD44_RS27280 0cb5c2a412db89af59f789f0ec679f8b 824 Gene3D G3DSA:3.40.50.1460 572 824 1.6E-16 T 28-03-2018 SMD44_RS27280 0cb5c2a412db89af59f789f0ec679f8b 824 Pfam PF12770 CHAT domain 523 823 8.6E-47 T 28-03-2018 IPR024983 CHAT domain SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 Pfam PF00106 short chain dehydrogenase 10 198 1.4E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 SUPERFAMILY SSF51735 5 238 2.0E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 Gene3D G3DSA:3.40.50.720 5 261 2.2E-55 T 28-03-2018 SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01895 df694a861ff3e3f082bda4cfe0a56eca 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 3.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 SUPERFAMILY SSF53335 6 116 2.54E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 SUPERFAMILY SSF53335 218 313 2.54E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 SUPERFAMILY SSF81799 117 218 6.8E-32 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 6 313 36.392 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 Gene3D G3DSA:1.10.150.170 115 220 3.0E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 PIRSF PIRSF004486 1 314 2.4E-98 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 312 6.2E-92 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 Pfam PF01795 MraW methylase family 4 312 2.5E-111 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS11070 4bdc1828e41a2af87984581d1d0eab9a 318 Gene3D G3DSA:3.40.50.150 4 109 2.0E-5 T 28-03-2018 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 SUPERFAMILY SSF56645 6 243 1.31E-61 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 PIRSF PIRSF016578 5 196 1.8E-9 T 28-03-2018 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 PIRSF PIRSF016578 237 356 4.2E-9 T 28-03-2018 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 Gene3D G3DSA:1.10.540.10 4 120 2.6E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 Gene3D G3DSA:2.40.110.10 122 222 1.3E-26 T 28-03-2018 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 375 1.2E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 Gene3D G3DSA:1.20.140.10 223 387 5.0E-39 T 28-03-2018 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 SUPERFAMILY SSF47203 228 385 9.67E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 204 4.8E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS18265 21c16e9e04e6c672e58260f6b4c62ffb 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 2.5E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS08160 2853bb4ac025af95c26b463276b771c9 497 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 1 484 5.8E-245 T 28-03-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 SMD44_RS08160 2853bb4ac025af95c26b463276b771c9 497 Pfam PF03136 Pup-ligase protein 1 451 4.8E-191 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMD44_RS08160 2853bb4ac025af95c26b463276b771c9 497 PIRSF PIRSF018077 4 494 9.9E-218 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMD44_RS16455 c22ac67f576ffb1ee8624801178f2ba6 360 SUPERFAMILY SSF53448 4 242 2.18E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16455 c22ac67f576ffb1ee8624801178f2ba6 360 SUPERFAMILY SSF53448 279 327 2.18E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16455 c22ac67f576ffb1ee8624801178f2ba6 360 Gene3D G3DSA:3.90.550.10 3 246 2.5E-57 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16455 c22ac67f576ffb1ee8624801178f2ba6 360 Pfam PF00483 Nucleotidyl transferase 4 236 3.6E-44 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD44_RS16455 c22ac67f576ffb1ee8624801178f2ba6 360 Gene3D G3DSA:2.160.10.10 255 356 1.6E-17 T 28-03-2018 SMD44_RS31665 a6c4dcf2b31c716414e729b687196a59 219 Hamap MF_00124 Thymidine kinase [tdk]. 1 195 28.177 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SMD44_RS31665 a6c4dcf2b31c716414e729b687196a59 219 SUPERFAMILY SSF52540 1 139 8.79E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31665 a6c4dcf2b31c716414e729b687196a59 219 Gene3D G3DSA:3.40.50.300 2 140 2.8E-33 T 28-03-2018 SMD44_RS31665 a6c4dcf2b31c716414e729b687196a59 219 Pfam PF00265 Thymidine kinase 4 192 3.3E-24 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SMD44_RS31665 a6c4dcf2b31c716414e729b687196a59 219 Gene3D G3DSA:3.30.60.20 143 215 5.2E-22 T 28-03-2018 SMD44_RS31665 a6c4dcf2b31c716414e729b687196a59 219 PIRSF PIRSF035805 1 204 1.4E-36 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SMD44_RS31665 a6c4dcf2b31c716414e729b687196a59 219 SUPERFAMILY SSF57716 144 196 8.08E-9 T 28-03-2018 SMD44_RS28380 f55a3288c7a3de6ef947ebb91ec70d79 356 SUPERFAMILY SSF53697 17 354 1.91E-73 T 28-03-2018 SMD44_RS28380 f55a3288c7a3de6ef947ebb91ec70d79 356 Gene3D G3DSA:3.40.50.10490 197 356 1.9E-36 T 28-03-2018 SMD44_RS28380 f55a3288c7a3de6ef947ebb91ec70d79 356 Pfam PF01380 SIS domain 54 176 3.2E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS28380 f55a3288c7a3de6ef947ebb91ec70d79 356 Pfam PF01380 SIS domain 213 338 2.3E-15 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS28380 f55a3288c7a3de6ef947ebb91ec70d79 356 Gene3D G3DSA:3.40.50.10490 3 187 4.4E-39 T 28-03-2018 SMD44_RS35395 e1f5c765f6097c3b0c728ea9a64e1b3e 320 ProSitePatterns PS00677 D-amino acid oxidases signature. 290 308 - T 28-03-2018 IPR006181 D-amino acid oxidase, conserved site GO:0003884|GO:0055114 Reactome: R-HSA-389661 SMD44_RS35395 e1f5c765f6097c3b0c728ea9a64e1b3e 320 SUPERFAMILY SSF51971 5 199 4.24E-29 T 28-03-2018 SMD44_RS35395 e1f5c765f6097c3b0c728ea9a64e1b3e 320 SUPERFAMILY SSF51971 260 318 4.24E-29 T 28-03-2018 SMD44_RS35395 e1f5c765f6097c3b0c728ea9a64e1b3e 320 Gene3D G3DSA:3.30.9.10 145 274 5.6E-28 T 28-03-2018 SMD44_RS35395 e1f5c765f6097c3b0c728ea9a64e1b3e 320 PIRSF PIRSF000189 5 320 5.8E-73 T 28-03-2018 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 Reactome: R-HSA-389661 SMD44_RS35395 e1f5c765f6097c3b0c728ea9a64e1b3e 320 SUPERFAMILY SSF54373 187 274 9.94E-20 T 28-03-2018 SMD44_RS35395 e1f5c765f6097c3b0c728ea9a64e1b3e 320 Gene3D G3DSA:3.50.50.60 3 144 1.3E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS35395 e1f5c765f6097c3b0c728ea9a64e1b3e 320 Pfam PF01266 FAD dependent oxidoreductase 8 313 1.3E-36 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS37850 9bf8d34b5b611cd50ae308833e734ab7 197 SUPERFAMILY SSF52317 9 188 3.44E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS37850 9bf8d34b5b611cd50ae308833e734ab7 197 Pfam PF01965 DJ-1/PfpI family 9 183 3.6E-43 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS37850 9bf8d34b5b611cd50ae308833e734ab7 197 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 12 185 4.6E-42 T 28-03-2018 IPR006286 Peptidase C56, PfpI SMD44_RS37850 9bf8d34b5b611cd50ae308833e734ab7 197 Gene3D G3DSA:3.40.50.880 1 197 2.8E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 162 384 2.7E-95 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 164 384 2.0E-38 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 PRINTS PR00046 Major sigma-70 factor signature 369 380 2.5E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 PRINTS PR00046 Major sigma-70 factor signature 192 205 2.5E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 PRINTS PR00046 Major sigma-70 factor signature 216 224 2.5E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 PRINTS PR00046 Major sigma-70 factor signature 337 349 2.5E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 PRINTS PR00046 Major sigma-70 factor signature 354 369 2.5E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 Gene3D G3DSA:1.10.10.10 237 290 2.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 Pfam PF04539 Sigma-70 region 3 250 307 2.6E-14 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 Gene3D G3DSA:1.10.10.10 324 387 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 Pfam PF04542 Sigma-70 region 2 168 237 5.5E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 SUPERFAMILY SSF88946 141 237 1.22E-32 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 Pfam PF04545 Sigma-70, region 4 333 382 3.5E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 Gene3D G3DSA:1.10.601.10 144 236 6.1E-29 T 28-03-2018 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 SUPERFAMILY SSF88659 304 384 1.12E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28415 7097912bbf8c95d33a1adbe526628c1d 388 SUPERFAMILY SSF88659 241 315 1.74E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS29125 9e3a8be6c2a71a933eaab3a1a840b534 469 Gene3D G3DSA:1.20.1250.20 47 241 6.1E-15 T 28-03-2018 SMD44_RS29125 9e3a8be6c2a71a933eaab3a1a840b534 469 SUPERFAMILY SSF103473 60 442 6.28E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS29125 9e3a8be6c2a71a933eaab3a1a840b534 469 Gene3D G3DSA:1.20.1250.20 256 446 7.4E-12 T 28-03-2018 SMD44_RS29125 9e3a8be6c2a71a933eaab3a1a840b534 469 Pfam PF07690 Major Facilitator Superfamily 64 373 5.4E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS38815 7f8b6fd1f7cb898b36195e0ceed79620 429 Pfam PF13489 Methyltransferase domain 81 238 1.4E-10 T 28-03-2018 SMD44_RS38815 7f8b6fd1f7cb898b36195e0ceed79620 429 Pfam PF08484 C-methyltransferase C-terminal domain 244 415 6.6E-60 T 28-03-2018 IPR013691 C-methyltransferase SMD44_RS38815 7f8b6fd1f7cb898b36195e0ceed79620 429 SUPERFAMILY SSF53335 61 249 6.8E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38815 7f8b6fd1f7cb898b36195e0ceed79620 429 Gene3D G3DSA:3.40.50.150 62 255 8.4E-26 T 28-03-2018 SMD44_RS38815 7f8b6fd1f7cb898b36195e0ceed79620 429 Pfam PF08421 Putative zinc binding domain 4 65 9.1E-22 T 28-03-2018 IPR013630 Methyltransferase putative zinc binding domain SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 PIRSF PIRSF000111 9 881 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 738 758 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 Gene3D G3DSA:3.40.309.10 242 422 1.6E-23 T 28-03-2018 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 650 678 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 Pfam PF00171 Aldehyde dehydrogenase family 17 284 6.5E-23 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 Gene3D G3DSA:3.40.605.10 4 241 1.7E-33 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 Pfam PF00465 Iron-containing alcohol dehydrogenase 476 864 1.5E-113 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 Gene3D G3DSA:1.20.1090.10 662 883 2.6E-60 T 28-03-2018 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 Gene3D G3DSA:3.40.50.1970 449 661 6.4E-50 T 28-03-2018 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 SUPERFAMILY SSF53720 24 472 4.71E-77 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS39245 2d7ef5870687d1589d859dcc7a85d9c6 886 SUPERFAMILY SSF56796 467 881 7.2E-113 T 28-03-2018 SMD44_RS03035 e6f5f518fce386ed2f1d4e99c1d39d7b 337 Gene3D G3DSA:3.40.50.720 1 137 3.3E-33 T 28-03-2018 SMD44_RS03035 e6f5f518fce386ed2f1d4e99c1d39d7b 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 238 1.8E-4 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS03035 e6f5f518fce386ed2f1d4e99c1d39d7b 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 125 3.1E-21 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS03035 e6f5f518fce386ed2f1d4e99c1d39d7b 337 Gene3D G3DSA:3.30.360.10 138 334 7.2E-33 T 28-03-2018 SMD44_RS03035 e6f5f518fce386ed2f1d4e99c1d39d7b 337 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 3 337 49.447 T 28-03-2018 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 SMD44_RS03035 e6f5f518fce386ed2f1d4e99c1d39d7b 337 SUPERFAMILY SSF55347 135 286 2.4E-15 T 28-03-2018 SMD44_RS03035 e6f5f518fce386ed2f1d4e99c1d39d7b 337 SUPERFAMILY SSF51735 2 155 1.25E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35530 0eafd09772fad30bc0ca69c9c022e742 216 Gene3D G3DSA:3.40.50.1580 20 206 1.9E-22 T 28-03-2018 SMD44_RS35530 0eafd09772fad30bc0ca69c9c022e742 216 SUPERFAMILY SSF53167 36 180 1.44E-22 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS35530 0eafd09772fad30bc0ca69c9c022e742 216 Pfam PF01048 Phosphorylase superfamily 35 176 5.3E-14 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS43115 e8aa3210a0a05949135b1f905ab002bf 227 SUPERFAMILY SSF47413 77 145 3.38E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS43115 e8aa3210a0a05949135b1f905ab002bf 227 Pfam PF13560 Helix-turn-helix domain 149 205 1.7E-6 T 28-03-2018 SMD44_RS43115 e8aa3210a0a05949135b1f905ab002bf 227 Gene3D G3DSA:1.10.260.40 146 217 1.2E-9 T 28-03-2018 SMD44_RS43115 e8aa3210a0a05949135b1f905ab002bf 227 SMART SM00530 148 203 8.0E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS43115 e8aa3210a0a05949135b1f905ab002bf 227 SMART SM00530 80 140 0.09 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS43115 e8aa3210a0a05949135b1f905ab002bf 227 SUPERFAMILY SSF47413 149 203 1.24E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS43115 e8aa3210a0a05949135b1f905ab002bf 227 Gene3D G3DSA:1.10.260.40 53 142 5.4E-9 T 28-03-2018 SMD44_RS22010 9d7c6e4f4e92aae043ee74b706409b95 392 SMART SM00530 11 66 6.5E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS22010 9d7c6e4f4e92aae043ee74b706409b95 392 SUPERFAMILY SSF47413 7 66 1.04E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS22010 9d7c6e4f4e92aae043ee74b706409b95 392 Gene3D G3DSA:1.25.40.10 148 378 4.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS22010 9d7c6e4f4e92aae043ee74b706409b95 392 Pfam PF13560 Helix-turn-helix domain 8 64 7.9E-13 T 28-03-2018 SMD44_RS22010 9d7c6e4f4e92aae043ee74b706409b95 392 Gene3D G3DSA:1.10.260.40 3 81 2.5E-15 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF58104 163 335 1.46E-8 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Pfam PF00672 HAMP domain 321 367 7.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Pfam PF00672 HAMP domain 877 918 8.6E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:3.40.50.2300 1722 1844 2.0E-37 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00387 1475 1608 5.2E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF158472 876 920 1.03E-5 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:1.10.287.130 1350 1424 1.3E-16 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF58104 339 470 4.71E-10 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF58104 615 705 6.02E-6 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Pfam PF13185 GAF domain 1130 1273 2.8E-16 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1361 1428 3.9E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1592 1605 1.9E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1551 1561 1.9E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1533 1547 1.9E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1568 1586 1.9E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF58104 707 874 1.26E-13 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00388 1360 1428 2.2E-23 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF58104 983 1105 8.63E-9 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Pfam PF00072 Response regulator receiver domain 1725 1835 2.2E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 974 1067 3.7E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 515 606 5.7E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 791 882 1.7E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 699 790 1.8E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 331 421 2.0E-19 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 883 973 1.1E-19 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 133 238 1.6E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 607 698 1.3E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 422 514 2.1E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:2.60.120.260 239 330 2.4E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1475 1607 6.3E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:3.30.565.10 1432 1613 6.4E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00448 1723 1837 7.5E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF58104 431 611 1.7E-10 T 28-03-2018 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00065 1131 1285 1.4E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF52172 1718 1842 6.69E-37 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 Gene3D G3DSA:3.30.450.40 1107 1321 1.8E-25 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF55781 1094 1275 2.47E-27 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF47384 1346 1430 6.28E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SUPERFAMILY SSF55874 1417 1610 1.57E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 687 739 3.7E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 319 371 6.5E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 1055 1107 2.5E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 963 1015 1.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 33 85 2.8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 227 279 3.2E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 595 647 7.6E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 871 923 1.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 503 555 1.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 125 187 0.0016 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 411 463 2.4E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31115 af3d523a7856f610b4fee0c2f4ef88ab 1844 SMART SM00304 779 831 3.2E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13850 875575b957093bad85567e1a0aae9701 328 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 11 319 4.8E-31 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 SMD44_RS13850 875575b957093bad85567e1a0aae9701 328 SUPERFAMILY SSF48019 203 321 2.38E-14 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SMD44_RS13850 875575b957093bad85567e1a0aae9701 328 Gene3D G3DSA:1.10.8.60 134 210 3.6E-12 T 28-03-2018 SMD44_RS13850 875575b957093bad85567e1a0aae9701 328 Gene3D G3DSA:1.20.272.10 211 327 5.5E-26 T 28-03-2018 SMD44_RS13850 875575b957093bad85567e1a0aae9701 328 Gene3D G3DSA:3.40.50.300 2 129 1.8E-10 T 28-03-2018 SMD44_RS13850 875575b957093bad85567e1a0aae9701 328 Pfam PF06144 DNA polymerase III, delta subunit 17 178 8.6E-10 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 SMD44_RS19390 167df432b72a701f50ec312d09bda258 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 9.4E-114 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SMD44_RS19390 167df432b72a701f50ec312d09bda258 258 SMART SM00382 29 229 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19390 167df432b72a701f50ec312d09bda258 258 SUPERFAMILY SSF52540 5 246 3.55E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19390 167df432b72a701f50ec312d09bda258 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS19390 167df432b72a701f50ec312d09bda258 258 Pfam PF00005 ABC transporter 21 176 1.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19390 167df432b72a701f50ec312d09bda258 258 Gene3D G3DSA:3.40.50.300 1 256 4.0E-58 T 28-03-2018 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 414 442 9.7E-8 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Gene3D G3DSA:1.10.150.20 549 614 7.6E-26 T 28-03-2018 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Gene3D G3DSA:1.10.150.20 440 548 5.8E-16 T 28-03-2018 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 20 499 7.0E-175 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Gene3D G3DSA:1.10.287.610 4 75 1.6E-26 T 28-03-2018 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Gene3D G3DSA:3.40.50.10190 615 715 4.3E-21 T 28-03-2018 IPR001357 BRCT domain SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Gene3D G3DSA:3.30.470.30 127 259 4.3E-52 T 28-03-2018 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 637 707 4.6E-12 T 28-03-2018 IPR001357 BRCT domain SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 PIRSF PIRSF001604 5 715 3.7E-241 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 12 325 9.4E-125 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 338 353 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 329 404 9.1E-28 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Hamap MF_01588 DNA ligase [ligA]. 11 711 51.599 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 SUPERFAMILY SSF50249 325 407 3.94E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 123 152 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 SUPERFAMILY SSF56091 11 325 2.13E-113 T 28-03-2018 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 SMART SM00532 12 456 2.2E-260 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Gene3D G3DSA:2.40.50.140 324 396 1.4E-25 T 28-03-2018 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 SMART SM00292 637 714 7.1E-10 T 28-03-2018 IPR001357 BRCT domain SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 Pfam PF12826 Helix-hairpin-helix motif 553 616 9.2E-23 T 28-03-2018 SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 SUPERFAMILY SSF47781 410 503 1.93E-44 T 28-03-2018 IPR010994 RuvA domain 2-like SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 SUPERFAMILY SSF47781 534 627 1.93E-44 T 28-03-2018 IPR010994 RuvA domain 2-like SMD44_RS29810 e917abfb042af82107122c3caa3c836e 727 SUPERFAMILY SSF52113 636 714 1.87E-18 T 28-03-2018 IPR001357 BRCT domain SMD44_RS21490 08ae115fcff9d27b4f393f07c50db151 712 SUPERFAMILY SSF52402 326 484 3.31E-24 T 28-03-2018 SMD44_RS21490 08ae115fcff9d27b4f393f07c50db151 712 Gene3D G3DSA:3.40.50.620 327 493 4.2E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS21490 08ae115fcff9d27b4f393f07c50db151 712 SUPERFAMILY SSF69864 493 694 2.22E-38 T 28-03-2018 SMD44_RS21490 08ae115fcff9d27b4f393f07c50db151 712 Pfam PF00764 Arginosuccinate synthase 331 663 4.0E-52 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS21490 08ae115fcff9d27b4f393f07c50db151 712 Gene3D G3DSA:3.90.1260.10 494 698 1.3E-45 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 PIRSF PIRSF016573 1 226 1.5E-109 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 SUPERFAMILY SSF55486 83 211 6.15E-29 T 28-03-2018 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 Gene3D G3DSA:3.40.390.10 82 214 6.9E-21 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 82 214 2.8E-78 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 90 214 8.0E-57 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 199 213 4.0E-63 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 89 115 4.0E-63 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 122 146 4.0E-63 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 147 171 4.0E-63 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS22000 3763454e0850c56dd475243a9157f948 226 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 172 196 4.0E-63 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Gene3D G3DSA:2.160.10.10 711 839 6.2E-14 T 28-03-2018 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Pfam PF00550 Phosphopantetheine attachment site 522 583 1.6E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 SMART SM00823 Phosphopantetheine attachment site 520 588 0.0015 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Gene3D G3DSA:2.30.38.10 329 404 1.0E-12 T 28-03-2018 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Pfam PF00501 AMP-binding enzyme 43 413 4.9E-68 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 63 437 5.0E-99 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 SUPERFAMILY SSF51161 723 838 8.46E-15 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 778 806 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Gene3D G3DSA:3.30.300.30 409 527 6.0E-24 T 28-03-2018 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Gene3D G3DSA:1.10.1200.10 528 596 7.6E-14 T 28-03-2018 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Gene3D G3DSA:2.160.10.10 915 1053 8.9E-5 T 28-03-2018 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Gene3D G3DSA:3.40.50.980 172 328 4.2E-33 T 28-03-2018 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 SUPERFAMILY SSF47336 518 585 1.73E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Gene3D G3DSA:3.40.50.980 33 171 7.1E-33 T 28-03-2018 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 Gene3D G3DSA:2.160.10.10 1180 1294 2.9E-10 T 28-03-2018 SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 607 1290 1.2E-255 T 28-03-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 SUPERFAMILY SSF51161 1179 1294 5.27E-14 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 SUPERFAMILY SSF51161 866 1051 1.12E-12 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS36040 648756a14a843b7d0d1eb6c42e8e7ef1 1295 SUPERFAMILY SSF56801 30 533 1.2E-111 T 28-03-2018 SMD44_RS21050 16f1c7b3b5ad898c2a9e4b2125811ca6 570 Gene3D G3DSA:1.10.510.10 168 314 1.4E-6 T 28-03-2018 SMD44_RS21050 16f1c7b3b5ad898c2a9e4b2125811ca6 570 Gene3D G3DSA:3.30.200.20 35 167 4.9E-4 T 28-03-2018 SMD44_RS21050 16f1c7b3b5ad898c2a9e4b2125811ca6 570 SUPERFAMILY SSF56112 88 249 2.82E-13 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS21050 16f1c7b3b5ad898c2a9e4b2125811ca6 570 Gene3D G3DSA:2.60.120.260 384 562 4.0E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS35255 aa861bb00701634efc94eb95eb2bc863 263 SUPERFAMILY SSF54593 136 260 1.61E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS35255 aa861bb00701634efc94eb95eb2bc863 263 Gene3D G3DSA:3.10.180.10 8 132 5.7E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS35255 aa861bb00701634efc94eb95eb2bc863 263 SUPERFAMILY SSF54593 9 123 1.06E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS35255 aa861bb00701634efc94eb95eb2bc863 263 Gene3D G3DSA:3.10.180.10 133 263 8.8E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS29740 c60d7657d15e5e57fa73404c5a29a3a1 336 Pfam PF13280 WYL domain 143 327 1.4E-30 T 28-03-2018 IPR026881 WYL domain SMD44_RS29740 c60d7657d15e5e57fa73404c5a29a3a1 336 Pfam PF08279 HTH domain 5 58 3.0E-17 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SMD44_RS29740 c60d7657d15e5e57fa73404c5a29a3a1 336 Gene3D G3DSA:3.10.129.10 141 312 2.9E-4 T 28-03-2018 SMD44_RS29740 c60d7657d15e5e57fa73404c5a29a3a1 336 Gene3D G3DSA:1.10.10.10 1 70 6.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29740 c60d7657d15e5e57fa73404c5a29a3a1 336 SUPERFAMILY SSF46785 3 57 3.24E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03655 e1e55a0cba1b3eb543e2a14cb4d911d4 325 SMART SM00382 44 231 4.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS03655 e1e55a0cba1b3eb543e2a14cb4d911d4 325 Pfam PF00005 ABC transporter 35 182 3.8E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS03655 e1e55a0cba1b3eb543e2a14cb4d911d4 325 Gene3D G3DSA:3.40.50.300 2 267 2.5E-58 T 28-03-2018 SMD44_RS03655 e1e55a0cba1b3eb543e2a14cb4d911d4 325 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS03655 e1e55a0cba1b3eb543e2a14cb4d911d4 325 SUPERFAMILY SSF52540 16 245 7.71E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25600 b70e635bd6a38a86c3645721873eaa8d 151 Gene3D G3DSA:3.100.10.10 43 150 1.6E-28 T 28-03-2018 SMD44_RS25600 b70e635bd6a38a86c3645721873eaa8d 151 ProSitePatterns PS00475 Ribosomal protein L15 signature. 114 144 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25600 b70e635bd6a38a86c3645721873eaa8d 151 SUPERFAMILY SSF52080 10 149 9.03E-40 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P SMD44_RS25600 b70e635bd6a38a86c3645721873eaa8d 151 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 9 150 18.797 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 SMD44_RS25600 b70e635bd6a38a86c3645721873eaa8d 151 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 32 148 1.3E-32 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P SMD44_RS25600 b70e635bd6a38a86c3645721873eaa8d 151 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 8 147 1.2E-44 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 SUPERFAMILY SSF55031 290 325 2.2E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 SUPERFAMILY SSF55031 200 242 2.2E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 79 88 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 Pfam PF07687 Peptidase dimerisation domain 198 325 1.5E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 Gene3D G3DSA:3.40.630.10 322 441 5.0E-4 T 28-03-2018 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 SUPERFAMILY SSF53187 351 439 7.71E-53 T 28-03-2018 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 SUPERFAMILY SSF53187 9 200 7.71E-53 T 28-03-2018 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 Gene3D G3DSA:3.40.630.10 2 203 8.4E-42 T 28-03-2018 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 Gene3D G3DSA:3.30.70.360 204 321 7.7E-18 T 28-03-2018 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 114 153 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 Pfam PF01546 Peptidase family M20/M25/M40 80 439 1.6E-35 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 PIRSF PIRSF036696 4 243 6.1E-30 T 28-03-2018 SMD44_RS34280 3ab22f20cfd52d5e1078ea0891fc9ada 441 PIRSF PIRSF036696 276 439 3.9E-8 T 28-03-2018 SMD44_RS17500 f4913cd3fdfb8bb80d068fdf7ba561ee 402 Gene3D G3DSA:3.30.565.10 203 393 8.8E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17500 f4913cd3fdfb8bb80d068fdf7ba561ee 402 SUPERFAMILY SSF55874 261 391 1.86E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17500 f4913cd3fdfb8bb80d068fdf7ba561ee 402 Pfam PF07730 Histidine kinase 176 242 1.1E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS01940 fb8fa177300b00b6e07bf4a61cbce571 458 Gene3D G3DSA:3.40.47.10 21 304 6.8E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01940 fb8fa177300b00b6e07bf4a61cbce571 458 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 314 413 7.9E-7 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS01940 fb8fa177300b00b6e07bf4a61cbce571 458 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 78 224 2.6E-11 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS01940 fb8fa177300b00b6e07bf4a61cbce571 458 SUPERFAMILY SSF53901 30 299 2.09E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01940 fb8fa177300b00b6e07bf4a61cbce571 458 Gene3D G3DSA:3.40.47.10 313 458 1.6E-12 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01940 fb8fa177300b00b6e07bf4a61cbce571 458 SUPERFAMILY SSF53901 263 457 9.79E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS08915 cae30ed00a7ec39739fe4f52676a6394 432 SUPERFAMILY SSF51679 1 428 1.96E-106 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS08915 cae30ed00a7ec39739fe4f52676a6394 432 Gene3D G3DSA:3.20.20.30 1 431 3.9E-93 T 28-03-2018 SMD44_RS08915 cae30ed00a7ec39739fe4f52676a6394 432 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 422 6.9E-124 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMD44_RS08915 cae30ed00a7ec39739fe4f52676a6394 432 PIRSF PIRSF000337 1 431 9.2E-144 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMD44_RS08915 cae30ed00a7ec39739fe4f52676a6394 432 Pfam PF00296 Luciferase-like monooxygenase 21 341 4.2E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 Gene3D G3DSA:1.10.443.10 517 672 5.3E-7 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 Gene3D G3DSA:1.10.10.10 77 169 1.6E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 Gene3D G3DSA:1.10.1740.10 2 76 1.5E-14 T 28-03-2018 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 SUPERFAMILY SSF88946 10 90 1.92E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 Pfam PF08281 Sigma-70, region 4 115 166 2.2E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 33 64 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 SUPERFAMILY SSF88659 106 168 2.99E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 Gene3D G3DSA:1.10.150.130 413 506 3.1E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 441 500 7.7E-8 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 167 3.6E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 SUPERFAMILY SSF56349 422 590 1.62E-12 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS05065 3f1245ff9c28db48bc201741bcdcbd26 686 Pfam PF04542 Sigma-70 region 2 18 78 2.4E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS02590 e1caab9ec569a707d77ceddc878d26d2 264 Pfam PF04672 S-adenosyl methyltransferase 7 263 3.4E-93 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS02590 e1caab9ec569a707d77ceddc878d26d2 264 Gene3D G3DSA:3.40.50.150 2 263 4.4E-40 T 28-03-2018 SMD44_RS02590 e1caab9ec569a707d77ceddc878d26d2 264 PIRSF PIRSF017393 1 264 1.3E-88 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS02590 e1caab9ec569a707d77ceddc878d26d2 264 SUPERFAMILY SSF53335 14 254 1.4E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS08695 0abb7234e184130fbf8efe5657765327 573 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS08695 0abb7234e184130fbf8efe5657765327 573 Gene3D G3DSA:3.30.200.20 1 99 7.0E-20 T 28-03-2018 SMD44_RS08695 0abb7234e184130fbf8efe5657765327 573 Gene3D G3DSA:1.10.510.10 100 325 3.6E-49 T 28-03-2018 SMD44_RS08695 0abb7234e184130fbf8efe5657765327 573 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS08695 0abb7234e184130fbf8efe5657765327 573 SMART SM00220 12 268 1.1E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS08695 0abb7234e184130fbf8efe5657765327 573 Pfam PF00069 Protein kinase domain 12 261 2.8E-43 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS08695 0abb7234e184130fbf8efe5657765327 573 SUPERFAMILY SSF56112 4 324 2.56E-69 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS12145 2b5ec562652e3d9c59a1af6eb309c47f 307 Gene3D G3DSA:3.90.1200.10 109 279 2.7E-17 T 28-03-2018 SMD44_RS12145 2b5ec562652e3d9c59a1af6eb309c47f 307 PIRSF PIRSF000707 1 307 9.6E-120 T 28-03-2018 IPR016259 Hygromycin-B kinase KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS12145 2b5ec562652e3d9c59a1af6eb309c47f 307 SUPERFAMILY SSF56112 43 276 8.5E-29 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS12145 2b5ec562652e3d9c59a1af6eb309c47f 307 Gene3D G3DSA:3.30.200.20 33 106 5.4E-5 T 28-03-2018 SMD44_RS12145 2b5ec562652e3d9c59a1af6eb309c47f 307 Pfam PF01636 Phosphotransferase enzyme family 46 270 2.2E-31 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS11655 9ead9c8ebaf8977425fb015c0dd0f0ee 279 SMART SM00866 119 260 2.2E-7 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS11655 9ead9c8ebaf8977425fb015c0dd0f0ee 279 SUPERFAMILY SSF64288 125 262 3.45E-19 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS11655 9ead9c8ebaf8977425fb015c0dd0f0ee 279 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 72 4.4E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS11655 9ead9c8ebaf8977425fb015c0dd0f0ee 279 SUPERFAMILY SSF46785 10 79 4.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11655 9ead9c8ebaf8977425fb015c0dd0f0ee 279 Gene3D G3DSA:1.10.10.10 3 77 2.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11655 9ead9c8ebaf8977425fb015c0dd0f0ee 279 Gene3D G3DSA:3.40.1410.10 80 263 8.3E-28 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS11655 9ead9c8ebaf8977425fb015c0dd0f0ee 279 SMART SM00345 16 75 1.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS11655 9ead9c8ebaf8977425fb015c0dd0f0ee 279 Pfam PF07702 UTRA domain 125 259 7.1E-14 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS25665 9076fcd5ba7fadc2afe23a4b45d2774d 147 Pfam PF00572 Ribosomal protein L13 14 137 7.5E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25665 9076fcd5ba7fadc2afe23a4b45d2774d 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 7.1E-61 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25665 9076fcd5ba7fadc2afe23a4b45d2774d 147 PIRSF PIRSF002181 2 147 1.4E-48 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25665 9076fcd5ba7fadc2afe23a4b45d2774d 147 SUPERFAMILY SSF52161 4 144 1.22E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25665 9076fcd5ba7fadc2afe23a4b45d2774d 147 Gene3D G3DSA:3.90.1180.10 1 147 2.6E-64 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25665 9076fcd5ba7fadc2afe23a4b45d2774d 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 SMD44_RS25665 9076fcd5ba7fadc2afe23a4b45d2774d 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 28.467 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 SUPERFAMILY SSF52540 2 92 6.57E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 SUPERFAMILY SSF52540 132 238 6.57E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 SUPERFAMILY SSF52540 336 520 8.61E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 SMART SM00382 26 236 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 SMART SM00382 354 521 2.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 Pfam PF00005 ABC transporter 17 191 5.5E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 Pfam PF00005 ABC transporter 345 475 5.4E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 Gene3D G3DSA:3.40.50.300 303 534 2.4E-47 T 28-03-2018 SMD44_RS20170 68b412afd5b12ab8bee636629a7d9762 536 Gene3D G3DSA:3.40.50.300 1 301 1.2E-48 T 28-03-2018 SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 7.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 Pfam PF00106 short chain dehydrogenase 12 193 2.6E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 188 0.0093 T 28-03-2018 SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 SUPERFAMILY SSF51735 9 246 1.59E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24280 ffa807d85b8a235bac6646d865e325a0 258 Gene3D G3DSA:3.40.50.720 1 244 2.5E-54 T 28-03-2018 SMD44_RS00335 804231752c15e8f81ee960cc235f2905 369 Pfam PF03841 L-seryl-tRNA selenium transferase 53 259 1.8E-9 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 SMD44_RS00335 804231752c15e8f81ee960cc235f2905 369 Gene3D G3DSA:3.40.640.10 40 247 1.9E-25 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS00335 804231752c15e8f81ee960cc235f2905 369 SUPERFAMILY SSF53383 13 366 3.35E-30 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 Gene3D G3DSA:2.40.50.140 17 94 8.1E-29 T 28-03-2018 SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 17 88 1.1E-34 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 Pfam PF00366 Ribosomal protein S17 22 89 1.8E-30 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 SUPERFAMILY SSF50249 17 94 2.14E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 ProSitePatterns PS00056 Ribosomal protein S17 signature. 68 80 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 17 92 24.955 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 22 88 2.0E-32 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 PRINTS PR00973 Ribosomal protein S17 family signature 78 85 1.4E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 PRINTS PR00973 Ribosomal protein S17 family signature 36 59 1.4E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25545 df5715ce4a2fe3d74399adfbde47055a 95 PRINTS PR00973 Ribosomal protein S17 family signature 68 78 1.4E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS14640 75d26a6f03d0b9d33fda081456b0d78d 627 SUPERFAMILY SSF52540 142 318 1.17E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14640 75d26a6f03d0b9d33fda081456b0d78d 627 Gene3D G3DSA:3.40.50.300 143 523 3.0E-4 T 28-03-2018 SMD44_RS14640 75d26a6f03d0b9d33fda081456b0d78d 627 Pfam PF13676 TIR domain 4 97 2.0E-12 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 SMD44_RS14640 75d26a6f03d0b9d33fda081456b0d78d 627 Gene3D G3DSA:3.40.50.10140 1 134 2.1E-16 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 SMD44_RS14640 75d26a6f03d0b9d33fda081456b0d78d 627 SUPERFAMILY SSF52200 2 86 5.1E-13 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 SUPERFAMILY SSF49785 572 692 1.4E-30 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 Pfam PF04542 Sigma-70 region 2 130 190 1.1E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 Gene3D G3DSA:1.10.1740.10 108 206 1.2E-19 T 28-03-2018 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 Gene3D G3DSA:1.10.10.10 236 361 3.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 SUPERFAMILY SSF88946 110 208 1.88E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 PRINTS PR01217 Proline rich extensin signature 474 486 3.1E-17 T 28-03-2018 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 PRINTS PR01217 Proline rich extensin signature 510 526 3.1E-17 T 28-03-2018 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 PRINTS PR01217 Proline rich extensin signature 451 467 3.1E-17 T 28-03-2018 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 PRINTS PR01217 Proline rich extensin signature 486 507 3.1E-17 T 28-03-2018 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 SUPERFAMILY SSF88659 242 301 5.79E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 126 302 1.5E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 SMART SM00776 550 694 1.6E-35 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMD44_RS19570 5f61b0386de0da899fac398ad9b0c19d 695 Pfam PF08305 NPCBM/NEW2 domain 584 692 1.6E-27 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 SUPERFAMILY SSF63737 3 193 1.57E-31 T 28-03-2018 SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 Gene3D G3DSA:1.10.390.10 275 425 1.4E-33 T 28-03-2018 SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 Gene3D G3DSA:2.60.40.1730 7 195 1.3E-37 T 28-03-2018 SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 282 297 6.8E-10 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 129 144 6.8E-10 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 313 6.8E-10 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 177 192 6.8E-10 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 SUPERFAMILY SSF55486 202 429 5.13E-47 T 28-03-2018 SMD44_RS06965 13295c7e594b61ca832f117f3073593c 442 Pfam PF01433 Peptidase family M1 domain 231 421 2.3E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS11635 31975e245b96f69b343720b36fee471e 407 Gene3D G3DSA:1.10.150.130 78 189 1.9E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS11635 31975e245b96f69b343720b36fee471e 407 Pfam PF00589 Phage integrase family 205 389 2.6E-15 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS11635 31975e245b96f69b343720b36fee471e 407 SUPERFAMILY SSF56349 82 393 1.08E-51 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS11635 31975e245b96f69b343720b36fee471e 407 Gene3D G3DSA:1.10.443.10 190 406 4.7E-31 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS19365 b97754d03622abb9d0a3608c9e84eed1 437 SMART SM00880 18 423 8.6E-5 T 28-03-2018 IPR007899 CHAD domain SMD44_RS19365 b97754d03622abb9d0a3608c9e84eed1 437 Pfam PF05235 CHAD domain 21 369 5.4E-25 T 28-03-2018 IPR007899 CHAD domain SMD44_RS02550 b254cfe5b12d47676d07d84437b48ebe 211 Pfam PF07681 DoxX 56 140 1.5E-17 T 28-03-2018 IPR032808 DoxX family SMD44_RS22275 5ec8e51d67408fbd065df878a5eff6c4 507 Pfam PF00271 Helicase conserved C-terminal domain 307 406 1.9E-25 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS22275 5ec8e51d67408fbd065df878a5eff6c4 507 Gene3D G3DSA:3.40.50.300 292 497 1.9E-40 T 28-03-2018 SMD44_RS22275 5ec8e51d67408fbd065df878a5eff6c4 507 Gene3D G3DSA:3.40.50.300 37 291 1.5E-48 T 28-03-2018 SMD44_RS22275 5ec8e51d67408fbd065df878a5eff6c4 507 SMART SM00490 325 406 8.3E-30 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS22275 5ec8e51d67408fbd065df878a5eff6c4 507 Pfam PF00270 DEAD/DEAH box helicase 96 263 1.1E-41 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS22275 5ec8e51d67408fbd065df878a5eff6c4 507 SUPERFAMILY SSF52540 144 422 3.08E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22275 5ec8e51d67408fbd065df878a5eff6c4 507 SMART SM00487 91 291 3.2E-47 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 Pfam PF01568 Molydopterin dinucleotide binding domain 654 771 1.1E-21 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 SUPERFAMILY SSF53706 419 632 3.02E-109 T 28-03-2018 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 SUPERFAMILY SSF53706 8 387 3.02E-109 T 28-03-2018 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 SMART SM00926 2 55 4.8E-12 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 Gene3D G3DSA:3.40.228.10 147 390 1.0E-55 T 28-03-2018 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 Gene3D G3DSA:3.40.228.10 417 499 1.1E-11 T 28-03-2018 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 Gene3D G3DSA:2.40.40.20 541 784 6.1E-29 T 28-03-2018 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 Gene3D G3DSA:2.20.25.90 3 60 1.4E-11 T 28-03-2018 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 Pfam PF00384 Molybdopterin oxidoreductase 59 468 1.7E-35 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 SUPERFAMILY SSF50692 654 780 4.07E-31 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 8 49 3.4E-8 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS08620 cee0136b92e6f53fb778750434838944 785 Gene3D G3DSA:3.40.50.740 61 146 1.7E-14 T 28-03-2018 SMD44_RS10855 a3882f5caac4a40b1b5add89437f0519 373 Pfam PF00155 Aminotransferase class I and II 30 364 1.7E-66 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS10855 a3882f5caac4a40b1b5add89437f0519 373 SUPERFAMILY SSF53383 29 367 5.98E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS10855 a3882f5caac4a40b1b5add89437f0519 373 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 10 368 54.254 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD44_RS10855 a3882f5caac4a40b1b5add89437f0519 373 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 12 366 2.4E-95 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD44_RS10855 a3882f5caac4a40b1b5add89437f0519 373 Gene3D G3DSA:3.40.640.10 46 258 1.2E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS10855 a3882f5caac4a40b1b5add89437f0519 373 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 228 237 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD44_RS10855 a3882f5caac4a40b1b5add89437f0519 373 Gene3D G3DSA:3.90.1150.10 259 368 3.4E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 SUPERFAMILY SSF46894 141 218 1.63E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 Pfam PF00072 Response regulator receiver domain 5 119 2.2E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 SMART SM00448 3 118 2.4E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 Gene3D G3DSA:1.10.10.10 130 222 9.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 5.0E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 SMART SM00421 155 212 6.9E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 SUPERFAMILY SSF52172 3 129 9.39E-33 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08835 372b0053ef2c0fc2585a65d38ebec5ea 223 Gene3D G3DSA:3.40.50.2300 2 129 2.6E-33 T 28-03-2018 SMD44_RS06065 54afe144f73044b1c8ea34b7f6f653bf 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 1.4E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06065 54afe144f73044b1c8ea34b7f6f653bf 194 SUPERFAMILY SSF46689 2 69 3.69E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS06065 54afe144f73044b1c8ea34b7f6f653bf 194 Gene3D G3DSA:1.10.10.60 1 58 6.1E-17 T 28-03-2018 SMD44_RS06065 54afe144f73044b1c8ea34b7f6f653bf 194 SUPERFAMILY SSF48498 78 193 9.46E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS06065 54afe144f73044b1c8ea34b7f6f653bf 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06065 54afe144f73044b1c8ea34b7f6f653bf 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06065 54afe144f73044b1c8ea34b7f6f653bf 194 Gene3D G3DSA:1.10.357.10 59 194 3.6E-26 T 28-03-2018 SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 203 2.5E-5 T 28-03-2018 SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 Gene3D G3DSA:3.40.50.720 1 263 3.8E-66 T 28-03-2018 SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 Pfam PF00106 short chain dehydrogenase 11 197 1.2E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.4E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.4E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.4E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.4E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.4E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.4E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11560 2636bbc634022534c5644054fabf923b 263 SUPERFAMILY SSF51735 5 262 1.21E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01175 e9ff7d18d2f28b75eb56da000d69ca28 232 Gene3D G3DSA:1.10.10.10 122 232 1.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01175 e9ff7d18d2f28b75eb56da000d69ca28 232 Gene3D G3DSA:3.40.50.2300 2 121 4.8E-39 T 28-03-2018 SMD44_RS01175 e9ff7d18d2f28b75eb56da000d69ca28 232 SMART SM00448 9 120 7.2E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS01175 e9ff7d18d2f28b75eb56da000d69ca28 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 228 7.8E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS01175 e9ff7d18d2f28b75eb56da000d69ca28 232 Pfam PF00072 Response regulator receiver domain 11 121 4.1E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS01175 e9ff7d18d2f28b75eb56da000d69ca28 232 SMART SM00862 154 229 2.1E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS01175 e9ff7d18d2f28b75eb56da000d69ca28 232 SUPERFAMILY SSF52172 8 184 1.71E-43 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 SUPERFAMILY SSF48452 367 481 9.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 Pfam PF00069 Protein kinase domain 16 270 1.1E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 SUPERFAMILY SSF56112 9 315 7.55E-76 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 Gene3D G3DSA:1.10.10.10 440 512 0.038 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 Gene3D G3DSA:1.25.40.10 328 439 1.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 Gene3D G3DSA:1.10.510.10 102 318 9.0E-48 T 28-03-2018 SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 SMART SM00220 16 281 2.6E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS16820 8d18dc47da038d7c0ac4787fe0e070e2 512 Gene3D G3DSA:3.30.200.20 5 101 2.4E-23 T 28-03-2018 SMD44_RS38225 dc1da694e8f236467e9c9bddc9e8af3a 291 SUPERFAMILY SSF161098 19 291 3.14E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS38225 dc1da694e8f236467e9c9bddc9e8af3a 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 282 1.0E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS38225 dc1da694e8f236467e9c9bddc9e8af3a 291 Gene3D G3DSA:1.10.3720.10 13 278 1.9E-35 T 28-03-2018 SMD44_RS27635 852fd81f44c7c494218eb316a0325113 150 Gene3D G3DSA:3.30.565.10 19 150 1.4E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27635 852fd81f44c7c494218eb316a0325113 150 SUPERFAMILY SSF55874 57 149 1.71E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27635 852fd81f44c7c494218eb316a0325113 150 Pfam PF13581 Histidine kinase-like ATPase domain 28 125 1.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14890 39adc530036b814a9d8becd6b41a4974 309 Gene3D G3DSA:3.40.710.10 53 284 8.6E-19 T 28-03-2018 SMD44_RS14890 39adc530036b814a9d8becd6b41a4974 309 SUPERFAMILY SSF56601 53 282 1.76E-30 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS14890 39adc530036b814a9d8becd6b41a4974 309 Pfam PF13354 Beta-lactamase enzyme family 120 236 7.8E-9 T 28-03-2018 SMD44_RS08090 5f68373be5a07cd78cf363f1a4b252e8 99 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 2.9E-17 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMD44_RS08090 5f68373be5a07cd78cf363f1a4b252e8 99 Pfam PF02416 mttA/Hcf106 family 4 54 2.5E-16 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMD44_RS08090 5f68373be5a07cd78cf363f1a4b252e8 99 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 80 21.22 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1075 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 SMART SM01096 426 547 1.0E-63 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Pfam PF02142 MGS-like domain 975 1065 1.6E-21 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 SUPERFAMILY SSF56059 128 406 1.13E-101 T 28-03-2018 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 SMART SM00851 974 1065 4.8E-28 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Gene3D G3DSA:3.30.470.20 120 408 1.6E-62 T 28-03-2018 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 170 184 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Gene3D G3DSA:3.40.50.1380 954 1099 1.6E-42 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Gene3D G3DSA:3.40.50.20 539 658 3.6E-58 T 28-03-2018 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 13.062 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 SUPERFAMILY SSF48108 401 553 4.32E-47 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 SUPERFAMILY SSF52440 557 678 6.19E-43 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Gene3D G3DSA:3.30.470.20 749 953 8.4E-31 T 28-03-2018 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Gene3D G3DSA:3.40.50.20 4 110 1.4E-36 T 28-03-2018 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 SUPERFAMILY SSF52335 960 1094 5.23E-34 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Gene3D G3DSA:3.30.1490.20 659 748 6.6E-26 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 SUPERFAMILY SSF56059 677 951 7.25E-90 T 28-03-2018 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 245 262 2.2E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 2.2E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.2E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 2.2E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 174 186 2.2E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 210 229 2.2E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.2E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 340 1.0E-66 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 677 879 2.1E-34 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Gene3D G3DSA:1.10.1030.10 412 538 5.3E-45 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 431 547 1.4E-38 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 713 727 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS07255 bd882f15017aea3890fe6748c6f881e9 1102 SUPERFAMILY SSF52440 2 127 3.17E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 SMART SM00354 7 77 6.4E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 Gene3D G3DSA:1.10.260.40 23 61 1.3E-20 T 28-03-2018 SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 SUPERFAMILY SSF53822 80 316 2.72E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 Gene3D G3DSA:3.40.50.2300 62 187 1.7E-30 T 28-03-2018 SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 Pfam PF13377 Periplasmic binding protein-like domain 181 315 7.4E-28 T 28-03-2018 SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 SUPERFAMILY SSF47413 7 64 3.94E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 Gene3D G3DSA:1.10.10.60 5 22 0.0014 T 28-03-2018 SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 2.6E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS35245 6cd669db78daba0cd06bdb5f8663f288 365 Gene3D G3DSA:3.40.50.2300 188 317 2.9E-46 T 28-03-2018 SMD44_RS06835 6d4d31f0eaa0e0efe1995ee28e1821c1 285 SUPERFAMILY SSF52266 2 193 1.83E-34 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS06835 6d4d31f0eaa0e0efe1995ee28e1821c1 285 Gene3D G3DSA:3.40.50.1110 1 197 7.6E-29 T 28-03-2018 SMD44_RS06835 6d4d31f0eaa0e0efe1995ee28e1821c1 285 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 8 184 2.3E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS30590 bae52d13e23bd3882cfd439ad9d43b9a 368 Gene3D G3DSA:3.20.20.70 28 343 1.5E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS30590 bae52d13e23bd3882cfd439ad9d43b9a 368 SUPERFAMILY SSF102114 113 342 3.14E-15 T 28-03-2018 SMD44_RS30590 bae52d13e23bd3882cfd439ad9d43b9a 368 Pfam PF04055 Radical SAM superfamily 124 295 9.3E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS30590 bae52d13e23bd3882cfd439ad9d43b9a 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 19 368 66.599 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS30590 bae52d13e23bd3882cfd439ad9d43b9a 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 367 2.3E-95 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS30590 bae52d13e23bd3882cfd439ad9d43b9a 368 PIRSF PIRSF006004 14 368 1.2E-123 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 Pfam PF00108 Thiolase, N-terminal domain 10 267 8.5E-95 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 SUPERFAMILY SSF53901 278 396 1.85E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 ProSitePatterns PS00099 Thiolases active site. 379 392 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 396 1.6E-136 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 Gene3D G3DSA:3.40.47.10 2 270 3.0E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 Gene3D G3DSA:3.40.47.10 271 395 4.8E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 PIRSF PIRSF000429 4 399 3.1E-118 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 Pfam PF02803 Thiolase, C-terminal domain 277 396 1.3E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 SUPERFAMILY SSF53901 10 275 3.63E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS29030 d96fe5c9243802ed2cd87535c8a3e97d 400 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD44_RS15170 092f54c55b38a75f1aa691768254204c 246 Gene3D G3DSA:3.40.50.2300 112 234 0.012 T 28-03-2018 SMD44_RS15170 092f54c55b38a75f1aa691768254204c 246 PIRSF PIRSF015736 2 240 8.0E-52 T 28-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase SMD44_RS15170 092f54c55b38a75f1aa691768254204c 246 Gene3D G3DSA:3.40.50.1860 27 111 6.7E-4 T 28-03-2018 SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 Pfam PF00072 Response regulator receiver domain 22 139 8.7E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 SMART SM00331 370 579 9.4E-29 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 401 579 5.4E-41 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 Gene3D G3DSA:3.30.450.40 157 344 9.9E-4 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 Gene3D G3DSA:3.40.50.2300 4 156 1.6E-27 T 28-03-2018 SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 SMART SM00448 20 139 1.7E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 SUPERFAMILY SSF52172 21 163 5.12E-27 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 SUPERFAMILY SSF81606 386 578 2.88E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS11835 e99514cf2e897aeda0ee168f5ad218b1 586 Gene3D G3DSA:3.60.40.10 345 582 8.7E-36 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 357 695 3.7E-114 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 Gene3D G3DSA:3.40.50.2300 231 329 1.4E-38 T 28-03-2018 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 10 146 3.8E-30 T 28-03-2018 IPR002178 PTS EIIA type-2 domain SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 14 133 8.9E-31 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 233 316 1.1E-27 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 SUPERFAMILY SSF55804 5 147 8.37E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 Gene3D G3DSA:3.40.930.10 1 150 2.6E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 234 323 1.0E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 Pfam PF02378 Phosphotransferase system, EIIC 365 642 5.9E-17 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMD44_RS17395 9be8ffa2bcb9e9c0e6453923a115dc26 723 SUPERFAMILY SSF52794 231 329 1.03E-31 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 601 617 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 SUPERFAMILY SSF55804 552 698 2.35E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 Pfam PF02378 Phosphotransferase system, EIIC 145 421 3.6E-22 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 556 683 1.8E-36 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 SUPERFAMILY SSF52794 13 108 8.2E-37 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 Gene3D G3DSA:3.40.930.10 551 700 2.9E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 135 471 1.2E-90 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 555 698 3.6E-34 T 28-03-2018 IPR002178 PTS EIIA type-2 domain SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 Gene3D G3DSA:3.40.50.2300 13 110 2.7E-39 T 28-03-2018 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 16 106 1.2E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMD44_RS16375 2477639d524fe0bb587203b5a4ac141a 700 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 16 97 2.2E-34 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SMD44_RS11450 28b4a8c3d24f19f2772ffa77ce667c15 389 SUPERFAMILY SSF55874 250 369 1.43E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11450 28b4a8c3d24f19f2772ffa77ce667c15 389 Gene3D G3DSA:3.30.565.10 149 371 7.9E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11450 28b4a8c3d24f19f2772ffa77ce667c15 389 Pfam PF07730 Histidine kinase 165 230 3.3E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS23695 4875d3d76eb6c9c25c6e253b1426b456 179 SUPERFAMILY SSF53271 5 177 5.9E-56 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS23695 4875d3d76eb6c9c25c6e253b1426b456 179 Gene3D G3DSA:3.40.50.2020 1 178 8.4E-45 T 28-03-2018 SMD44_RS23695 4875d3d76eb6c9c25c6e253b1426b456 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 1.0E-25 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD44_RS23695 4875d3d76eb6c9c25c6e253b1426b456 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 1.9E-66 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 SMD44_RS25070 c75147866826b9d60cfbe333e08ed3f1 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.878 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SMD44_RS25070 c75147866826b9d60cfbe333e08ed3f1 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 1.8E-23 T 28-03-2018 SMD44_RS28355 4a31af4220c49d33fcf25c6e0e294488 424 SUPERFAMILY SSF53850 36 416 4.76E-68 T 28-03-2018 SMD44_RS28355 4a31af4220c49d33fcf25c6e0e294488 424 Pfam PF01547 Bacterial extracellular solute-binding protein 48 335 1.1E-40 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS28355 4a31af4220c49d33fcf25c6e0e294488 424 Gene3D G3DSA:3.40.190.10 39 163 5.7E-18 T 28-03-2018 SMD44_RS28355 4a31af4220c49d33fcf25c6e0e294488 424 Gene3D G3DSA:3.40.190.10 164 364 6.0E-38 T 28-03-2018 SMD44_RS39235 fa2419a14c8fa06d33ea5a02e53c240a 753 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 16 752 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 SMD44_RS39235 fa2419a14c8fa06d33ea5a02e53c240a 753 Gene3D G3DSA:3.20.70.20 9 753 6.4E-284 T 28-03-2018 SMD44_RS39235 fa2419a14c8fa06d33ea5a02e53c240a 753 PIRSF PIRSF000379 14 753 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 SMD44_RS39235 fa2419a14c8fa06d33ea5a02e53c240a 753 SUPERFAMILY SSF51998 15 752 2.79E-268 T 28-03-2018 SMD44_RS39235 fa2419a14c8fa06d33ea5a02e53c240a 753 Pfam PF02901 Pyruvate formate lyase-like 30 612 3.0E-195 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 SMD44_RS39235 fa2419a14c8fa06d33ea5a02e53c240a 753 Pfam PF01228 Glycine radical 628 734 8.1E-38 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 SMD44_RS39235 fa2419a14c8fa06d33ea5a02e53c240a 753 ProSitePatterns PS00850 Glycine radical domain signature. 723 731 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site SMD44_RS02560 f068e1543214dd28fd44cdb51ef06041 75 Gene3D G3DSA:3.30.70.20 17 75 4.1E-6 T 28-03-2018 SMD44_RS02560 f068e1543214dd28fd44cdb51ef06041 75 Gene3D G3DSA:3.30.70.20 1 16 0.072 T 28-03-2018 SMD44_RS02560 f068e1543214dd28fd44cdb51ef06041 75 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.3E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS02560 f068e1543214dd28fd44cdb51ef06041 75 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 1.3E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS02560 f068e1543214dd28fd44cdb51ef06041 75 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.3E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS02560 f068e1543214dd28fd44cdb51ef06041 75 Pfam PF13459 4Fe-4S single cluster domain 3 60 3.6E-14 T 28-03-2018 SMD44_RS02560 f068e1543214dd28fd44cdb51ef06041 75 SUPERFAMILY SSF54862 2 61 1.01E-13 T 28-03-2018 SMD44_RS28805 3c1e046ef27a10af4a5d9987c1d32b36 352 PIRSF PIRSF038945 1 351 2.2E-167 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 SMD44_RS28805 3c1e046ef27a10af4a5d9987c1d32b36 352 Gene3D G3DSA:3.40.50.1100 147 334 1.5E-51 T 28-03-2018 SMD44_RS28805 3c1e046ef27a10af4a5d9987c1d32b36 352 TIGRFAM TIGR00260 thrC: threonine synthase 9 326 5.0E-97 T 28-03-2018 IPR004450 Threonine synthase-like SMD44_RS28805 3c1e046ef27a10af4a5d9987c1d32b36 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 319 3.8E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS28805 3c1e046ef27a10af4a5d9987c1d32b36 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SMD44_RS28805 3c1e046ef27a10af4a5d9987c1d32b36 352 SUPERFAMILY SSF53686 5 333 3.01E-102 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS28805 3c1e046ef27a10af4a5d9987c1d32b36 352 Gene3D G3DSA:3.40.50.1100 38 146 1.9E-24 T 28-03-2018 SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 TIGRFAM TIGR02961 allantoicase: allantoicase 34 354 1.3E-124 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 SUPERFAMILY SSF49785 212 356 6.52E-44 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 Pfam PF03561 Allantoicase repeat 44 203 1.1E-44 T 28-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 Pfam PF03561 Allantoicase repeat 226 354 2.2E-35 T 28-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 Gene3D G3DSA:2.60.120.260 212 359 5.7E-49 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 Gene3D G3DSA:2.60.120.260 18 208 2.1E-65 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 PIRSF PIRSF016516 22 358 6.1E-92 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 Hamap MF_00813 Probable allantoicase [alc]. 10 357 44.633 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD44_RS33545 8a2a99d1b9b582df04a8c81e937f282b 373 SUPERFAMILY SSF49785 26 206 9.64E-54 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS13230 0e483e863fd57cc7946bb8790aa55687 151 Pfam PF05099 Tellurite resistance protein TerB 10 150 9.5E-30 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal SMD44_RS13230 0e483e863fd57cc7946bb8790aa55687 151 Gene3D G3DSA:1.10.3680.10 3 151 1.4E-23 T 28-03-2018 IPR029024 TerB-like SMD44_RS13230 0e483e863fd57cc7946bb8790aa55687 151 SUPERFAMILY SSF158682 15 150 1.2E-22 T 28-03-2018 SMD44_RS03860 a107c6910a71aaac75d9ffd32a151dd3 331 Pfam PF13280 WYL domain 139 318 2.5E-38 T 28-03-2018 IPR026881 WYL domain SMD44_RS03860 a107c6910a71aaac75d9ffd32a151dd3 331 SUPERFAMILY SSF46785 4 59 4.92E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03860 a107c6910a71aaac75d9ffd32a151dd3 331 Gene3D G3DSA:1.10.10.10 2 64 6.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03860 a107c6910a71aaac75d9ffd32a151dd3 331 PIRSF PIRSF016838 2 56 0.0042 T 28-03-2018 IPR028349 Protein PafC SMD44_RS03860 a107c6910a71aaac75d9ffd32a151dd3 331 PIRSF PIRSF016838 75 326 3.1E-10 T 28-03-2018 IPR028349 Protein PafC SMD44_RS03860 a107c6910a71aaac75d9ffd32a151dd3 331 Pfam PF08279 HTH domain 5 60 4.6E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 SUPERFAMILY SSF161098 83 265 3.66E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Gene3D G3DSA:1.10.3720.10 8 275 1.9E-31 T 28-03-2018 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Gene3D G3DSA:1.20.58.60 809 858 0.12 T 28-03-2018 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 SUPERFAMILY SSF53850 606 865 7.67E-68 T 28-03-2018 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Gene3D G3DSA:3.40.190.10 330 430 6.5E-18 T 28-03-2018 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Gene3D G3DSA:3.40.190.10 602 700 6.2E-16 T 28-03-2018 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Gene3D G3DSA:3.40.190.100 701 808 7.4E-33 T 28-03-2018 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Gene3D G3DSA:3.40.190.100 431 545 5.3E-36 T 28-03-2018 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 262 3.5E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 SUPERFAMILY SSF53850 334 593 3.48E-76 T 28-03-2018 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 609 857 1.2E-60 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD44_RS08020 b9a047975274f52376ca6ae803c02936 869 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 337 586 6.5E-67 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD44_RS05470 9f5289160202964e2899db08569764de 442 SUPERFAMILY SSF103473 22 424 3.01E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS05470 9f5289160202964e2899db08569764de 442 Gene3D G3DSA:1.20.1250.20 15 217 3.1E-17 T 28-03-2018 SMD44_RS05470 9f5289160202964e2899db08569764de 442 Gene3D G3DSA:1.20.1250.20 236 425 2.3E-16 T 28-03-2018 SMD44_RS05470 9f5289160202964e2899db08569764de 442 Pfam PF07690 Major Facilitator Superfamily 28 390 3.3E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.897 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 SUPERFAMILY SSF54999 5 102 1.02E-38 T 28-03-2018 IPR027486 Ribosomal protein S10 domain SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 8.0E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 SMART SM01403 7 101 3.5E-59 T 28-03-2018 IPR027486 Ribosomal protein S10 domain SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 Gene3D G3DSA:3.30.70.600 4 102 1.0E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-47 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.6E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.6E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25495 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.6E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS28015 92711c225fbc86018da9c0261d6edfa6 684 SUPERFAMILY SSF53756 245 583 3.23E-53 T 28-03-2018 SMD44_RS28015 92711c225fbc86018da9c0261d6edfa6 684 Gene3D G3DSA:3.40.50.2000 380 567 4.2E-40 T 28-03-2018 SMD44_RS28015 92711c225fbc86018da9c0261d6edfa6 684 Pfam PF13692 Glycosyl transferases group 1 390 547 2.3E-24 T 28-03-2018 SMD44_RS28015 92711c225fbc86018da9c0261d6edfa6 684 Gene3D G3DSA:3.40.50.2000 21 379 3.6E-5 T 28-03-2018 SMD44_RS28015 92711c225fbc86018da9c0261d6edfa6 684 Pfam PF11997 Domain of unknown function (DUF3492) 2 68 2.0E-11 T 28-03-2018 IPR022622 Domain of unknown function DUF3492 SMD44_RS28015 92711c225fbc86018da9c0261d6edfa6 684 Pfam PF11997 Domain of unknown function (DUF3492) 186 361 1.3E-11 T 28-03-2018 IPR022622 Domain of unknown function DUF3492 SMD44_RS15740 7c7a7882fd6ef22c97f701f67ada935f 469 SUPERFAMILY SSF55103 205 468 2.78E-62 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMD44_RS15740 7c7a7882fd6ef22c97f701f67ada935f 469 Gene3D G3DSA:3.30.465.10 107 252 3.0E-41 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS15740 7c7a7882fd6ef22c97f701f67ada935f 469 Gene3D G3DSA:1.10.45.10 429 468 1.1E-17 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SMD44_RS15740 7c7a7882fd6ef22c97f701f67ada935f 469 SUPERFAMILY SSF56176 17 230 3.13E-71 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS15740 7c7a7882fd6ef22c97f701f67ada935f 469 Gene3D G3DSA:3.30.43.10 3 106 6.6E-24 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD44_RS15740 7c7a7882fd6ef22c97f701f67ada935f 469 Gene3D G3DSA:3.40.462.10 357 423 0.0011 T 28-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain SMD44_RS15740 7c7a7882fd6ef22c97f701f67ada935f 469 Pfam PF01565 FAD binding domain 54 192 1.5E-39 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD44_RS15740 7c7a7882fd6ef22c97f701f67ada935f 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 230 468 1.7E-67 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMD44_RS35600 69c4153064beda7c4b62309e8de0735b 192 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 122 2.5E-8 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS35600 69c4153064beda7c4b62309e8de0735b 192 SUPERFAMILY SSF69118 1 174 1.68E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS35600 69c4153064beda7c4b62309e8de0735b 192 Gene3D G3DSA:1.20.1290.10 31 180 1.6E-25 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS08630 5c302f648c4a0803a2a9234c7f97cf9f 442 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 18 442 72.994 T 28-03-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 SMD44_RS08630 5c302f648c4a0803a2a9234c7f97cf9f 442 Pfam PF04209 homogentisate 1,2-dioxygenase 19 440 6.0E-216 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 SMD44_RS08630 5c302f648c4a0803a2a9234c7f97cf9f 442 Gene3D G3DSA:2.60.120.10 288 410 1.3E-53 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS08630 5c302f648c4a0803a2a9234c7f97cf9f 442 Gene3D G3DSA:2.60.120.10 209 250 3.4E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS08630 5c302f648c4a0803a2a9234c7f97cf9f 442 SUPERFAMILY SSF51182 17 442 2.61E-165 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS08630 5c302f648c4a0803a2a9234c7f97cf9f 442 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 17 440 1.2E-222 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 SMART SM00490 608 698 1.9E-4 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 Gene3D G3DSA:1.10.3210.10 4 253 1.9E-11 T 28-03-2018 SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 Pfam PF01966 HD domain 36 225 3.1E-6 T 28-03-2018 IPR006674 HD domain SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 Gene3D G3DSA:3.40.50.300 563 711 2.6E-9 T 28-03-2018 SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 Gene3D G3DSA:3.40.50.300 254 513 7.2E-16 T 28-03-2018 SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 SMART SM00471 31 243 0.0012 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 SUPERFAMILY SSF109604 35 157 4.08E-9 T 28-03-2018 SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 35 230 4.0E-24 T 28-03-2018 IPR006483 CRISPR-associated Cas3-HD domain SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 303 697 6.9E-33 T 28-03-2018 IPR006474 Helicase Cas3, CRISPR-associated, core SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 SUPERFAMILY SSF52540 561 698 1.38E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 SUPERFAMILY SSF52540 427 499 1.38E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13125 fc80d4c786d6a5e6f5d9a7cc1214e65d 962 SUPERFAMILY SSF52540 303 352 1.38E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 159 2.2E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 Gene3D G3DSA:2.40.30.10 211 318 1.4E-23 T 28-03-2018 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 SUPERFAMILY SSF54980 319 416 9.93E-9 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 Pfam PF03144 Elongation factor Tu domain 2 235 305 3.6E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 PRINTS PR00315 GTP-binding elongation factor signature 81 91 1.5E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 PRINTS PR00315 GTP-binding elongation factor signature 133 142 1.5E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 PRINTS PR00315 GTP-binding elongation factor signature 55 63 1.5E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 PRINTS PR00315 GTP-binding elongation factor signature 97 108 1.5E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.5E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 SUPERFAMILY SSF50447 211 315 9.15E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 SUPERFAMILY SSF50447 162 184 9.15E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 Gene3D G3DSA:2.40.50.250 511 601 4.3E-36 T 28-03-2018 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 SUPERFAMILY SSF54980 427 541 9.11E-27 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 Gene3D G3DSA:3.30.70.870 319 430 1.2E-26 T 28-03-2018 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 626 5.1E-286 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 Pfam PF00009 Elongation factor Tu GTP binding domain 6 211 1.6E-51 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 Gene3D G3DSA:3.40.50.300 2 210 2.9E-35 T 28-03-2018 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 Gene3D G3DSA:3.30.70.240 431 507 5.1E-16 T 28-03-2018 SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 Pfam PF00679 Elongation factor G C-terminus 425 508 1.6E-20 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SMD44_RS27680 35f2dbc9d2fa6c11e5c2b33659232335 635 SUPERFAMILY SSF52540 4 221 8.92E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS38375 1cbd9c8f4920a683c37a4966f12d339d 181 SUPERFAMILY SSF54637 60 158 8.48E-12 T 28-03-2018 IPR029069 HotDog domain SMD44_RS38375 1cbd9c8f4920a683c37a4966f12d339d 181 Gene3D G3DSA:3.10.129.10 1 40 0.026 T 28-03-2018 SMD44_RS38375 1cbd9c8f4920a683c37a4966f12d339d 181 Gene3D G3DSA:3.10.129.10 41 167 1.3E-10 T 28-03-2018 SMD44_RS13445 fa6ec7baf853a1f7591bb35dbae5a82c 617 Pfam PF13520 Amino acid permease 62 428 5.6E-25 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 89 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 Gene3D G3DSA:1.20.1250.20 18 204 1.5E-28 T 28-03-2018 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 Pfam PF07690 Major Facilitator Superfamily 24 422 1.4E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 5.3E-6 T 28-03-2018 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 5.3E-6 T 28-03-2018 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 82 104 5.3E-6 T 28-03-2018 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 Gene3D G3DSA:1.20.1250.20 266 484 5.1E-21 T 28-03-2018 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 Gene3D G3DSA:1.20.1250.20 208 265 0.2 T 28-03-2018 SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 SUPERFAMILY SSF103473 259 477 1.22E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS25755 e0beff752b681fc983e98377a745551b 500 SUPERFAMILY SSF103473 8 203 1.22E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS19980 16a64e346b086bb00dfebae593086b75 227 SUPERFAMILY SSF52317 3 221 2.22E-69 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS19980 16a64e346b086bb00dfebae593086b75 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 222 3.5E-82 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19980 16a64e346b086bb00dfebae593086b75 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 221 40.564 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19980 16a64e346b086bb00dfebae593086b75 227 SMART SM01211 2 223 7.4E-123 T 28-03-2018 SMD44_RS19980 16a64e346b086bb00dfebae593086b75 227 PIRSF PIRSF001586 1 226 1.8E-84 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19980 16a64e346b086bb00dfebae593086b75 227 Gene3D G3DSA:3.40.50.880 1 225 1.2E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS19980 16a64e346b086bb00dfebae593086b75 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 204 2.6E-35 T 28-03-2018 SMD44_RS29690 1f31b20e05d0d2d762bc741b481504aa 334 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 34 79 1.0E-10 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS29690 1f31b20e05d0d2d762bc741b481504aa 334 SUPERFAMILY SSF161098 117 315 1.3E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS29690 1f31b20e05d0d2d762bc741b481504aa 334 Gene3D G3DSA:1.10.3720.10 37 322 5.4E-52 T 28-03-2018 SMD44_RS29690 1f31b20e05d0d2d762bc741b481504aa 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 331 5.7E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 Pfam PF00196 Bacterial regulatory proteins, luxR family 230 284 1.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 Gene3D G3DSA:1.10.10.10 224 292 6.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 SMART SM00421 228 285 9.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 SUPERFAMILY SSF55781 15 153 7.85E-9 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 SUPERFAMILY SSF46894 223 291 1.09E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 Gene3D G3DSA:3.30.450.40 9 169 1.1E-12 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 245 261 1.4E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 261 273 1.4E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33280 81605e0c4c05bad04860e9fda1900835 292 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 231 245 1.4E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS34065 d4f1b2b58576a4d2d2154d436db3990f 205 Pfam PF03029 Conserved hypothetical ATP binding protein 27 194 1.2E-23 T 28-03-2018 IPR004130 GPN-loop GTPase SMD44_RS34065 d4f1b2b58576a4d2d2154d436db3990f 205 Gene3D G3DSA:3.40.50.300 17 198 1.6E-19 T 28-03-2018 SMD44_RS34065 d4f1b2b58576a4d2d2154d436db3990f 205 SUPERFAMILY SSF52540 21 195 3.63E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23505 ad0a837834d19fa837a2aa6e5b70428d 274 SMART SM00448 3 128 1.4E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23505 ad0a837834d19fa837a2aa6e5b70428d 274 Gene3D G3DSA:1.10.10.10 145 252 3.6E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23505 ad0a837834d19fa837a2aa6e5b70428d 274 Pfam PF00072 Response regulator receiver domain 5 129 4.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23505 ad0a837834d19fa837a2aa6e5b70428d 274 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 245 3.6E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS23505 ad0a837834d19fa837a2aa6e5b70428d 274 SUPERFAMILY SSF46894 145 246 1.35E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS23505 ad0a837834d19fa837a2aa6e5b70428d 274 SMART SM00862 169 245 4.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS23505 ad0a837834d19fa837a2aa6e5b70428d 274 Gene3D G3DSA:3.40.50.2300 3 144 1.1E-34 T 28-03-2018 SMD44_RS23505 ad0a837834d19fa837a2aa6e5b70428d 274 SUPERFAMILY SSF52172 4 138 2.13E-38 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 SMART SM00345 7 66 6.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 SMART SM00895 92 214 4.3E-21 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 2.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 2.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 Gene3D G3DSA:1.20.120.530 71 223 7.6E-33 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 4.9E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 Pfam PF07729 FCD domain 92 213 4.1E-26 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 SUPERFAMILY SSF48008 89 221 8.11E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 Gene3D G3DSA:1.10.10.10 2 68 7.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08275 f38c56db15ca2a62bbe7cee1234abe49 223 SUPERFAMILY SSF46785 4 70 6.68E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31295 82bde3fb055178c71c572961f9878d1c 283 Pfam PF04672 S-adenosyl methyltransferase 22 282 8.7E-106 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS31295 82bde3fb055178c71c572961f9878d1c 283 PIRSF PIRSF017393 10 283 1.7E-103 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS31295 82bde3fb055178c71c572961f9878d1c 283 Gene3D G3DSA:3.40.50.150 10 283 8.5E-55 T 28-03-2018 SMD44_RS31295 82bde3fb055178c71c572961f9878d1c 283 SUPERFAMILY SSF53335 30 265 4.11E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS25365 3d4883abe5b57a5998d3c316f457a834 154 PIRSF PIRSF018072 1 149 5.5E-59 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 SMD44_RS25365 3d4883abe5b57a5998d3c316f457a834 154 SUPERFAMILY SSF54637 7 147 6.58E-40 T 28-03-2018 IPR029069 HotDog domain SMD44_RS25365 3d4883abe5b57a5998d3c316f457a834 154 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 1.7E-35 T 28-03-2018 SMD44_RS25365 3d4883abe5b57a5998d3c316f457a834 154 Gene3D G3DSA:3.10.129.10 3 153 1.1E-40 T 28-03-2018 SMD44_RS25365 3d4883abe5b57a5998d3c316f457a834 154 Hamap MF_00799 UPF0336 protein . 1 148 36.935 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 SUPERFAMILY SSF56112 192 471 1.52E-41 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 Pfam PF00069 Protein kinase domain 203 402 3.1E-25 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 SUPERFAMILY SSF48452 647 744 5.81E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 Pfam PF16918 Protein kinase G tetratricopeptide repeat 569 897 6.0E-82 T 28-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 Gene3D G3DSA:3.30.200.20 190 289 1.4E-15 T 28-03-2018 SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 Gene3D G3DSA:1.25.40.10 471 695 1.6E-34 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 Gene3D G3DSA:1.25.40.10 696 770 1.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 Gene3D G3DSA:1.10.510.10 290 464 2.9E-22 T 28-03-2018 SMD44_RS14500 9b51fe4f1a1c045e5a549300d57aa893 899 Pfam PF16919 Protein kinase G rubredoxin domain 73 201 8.3E-39 T 28-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMD44_RS29515 8ad02145316f1d02d01b62d9ce360165 615 Gene3D G3DSA:3.40.50.300 358 615 2.7E-62 T 28-03-2018 SMD44_RS29515 8ad02145316f1d02d01b62d9ce360165 615 SMART SM00382 402 588 2.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29515 8ad02145316f1d02d01b62d9ce360165 615 Pfam PF00664 ABC transporter transmembrane region 35 305 1.9E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS29515 8ad02145316f1d02d01b62d9ce360165 615 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS29515 8ad02145316f1d02d01b62d9ce360165 615 SUPERFAMILY SSF52540 368 609 7.5E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29515 8ad02145316f1d02d01b62d9ce360165 615 Pfam PF00005 ABC transporter 393 541 5.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS29515 8ad02145316f1d02d01b62d9ce360165 615 SUPERFAMILY SSF90123 22 336 8.37E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS29515 8ad02145316f1d02d01b62d9ce360165 615 Gene3D G3DSA:1.20.1560.10 14 341 3.6E-60 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:1.10.150.200 810 861 6.1E-11 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:1.10.150.200 730 782 8.8E-6 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SUPERFAMILY SSF52540 238 455 4.91E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:3.40.50.300 241 396 4.0E-14 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SMART SM00862 3 70 2.1E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Pfam PF00486 Transcriptional regulatory protein, C terminal 3 70 8.3E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SMART SM01043 77 218 1.5E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 PRINTS PR00364 Disease resistance protein signature 438 452 9.4E-8 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 PRINTS PR00364 Disease resistance protein signature 271 286 9.4E-8 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 PRINTS PR00364 Disease resistance protein signature 350 364 9.4E-8 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:1.25.40.10 618 729 0.0064 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SUPERFAMILY SSF46894 2 70 5.1E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Pfam PF00931 NB-ARC domain 259 450 1.1E-7 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:1.10.10.10 490 567 2.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SUPERFAMILY SSF48452 72 241 7.21E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SUPERFAMILY SSF48452 677 809 4.17E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:3.30.70.100 783 809 4.4E-5 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:3.30.70.100 862 901 1.8E-5 T 28-03-2018 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SMART SM00028 695 728 37.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SMART SM00028 815 848 0.69 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SMART SM00028 735 768 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SMART SM00028 775 808 0.27 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SMART SM00028 855 888 0.3 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:1.25.40.10 79 238 3.7E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Gene3D G3DSA:1.10.10.10 1 78 4.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 SUPERFAMILY SSF48452 790 899 9.83E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Pfam PF03704 Bacterial transcriptional activator domain 77 218 1.7E-34 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS00820 0f3f603aa883e6f61faedab72b9ab057 902 Pfam PF13424 Tetratricopeptide repeat 814 887 4.9E-11 T 28-03-2018 SMD44_RS37540 b72a5e98c100ff32e8325ecf9e1db920 114 Pfam PF14559 Tetratricopeptide repeat 22 84 3.2E-9 T 28-03-2018 SMD44_RS37540 b72a5e98c100ff32e8325ecf9e1db920 114 SUPERFAMILY SSF48452 11 112 1.24E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS37540 b72a5e98c100ff32e8325ecf9e1db920 114 Gene3D G3DSA:1.25.40.10 7 114 4.7E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34015 7390efc6954b7fa389fe4a40a5000db3 239 SMART SM00895 88 212 1.2E-16 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS34015 7390efc6954b7fa389fe4a40a5000db3 239 SUPERFAMILY SSF46785 13 82 5.84E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34015 7390efc6954b7fa389fe4a40a5000db3 239 Gene3D G3DSA:1.20.120.530 81 230 1.3E-35 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS34015 7390efc6954b7fa389fe4a40a5000db3 239 SUPERFAMILY SSF48008 84 217 3.4E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS34015 7390efc6954b7fa389fe4a40a5000db3 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 78 1.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS34015 7390efc6954b7fa389fe4a40a5000db3 239 Pfam PF07729 FCD domain 90 210 1.4E-23 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS34015 7390efc6954b7fa389fe4a40a5000db3 239 Gene3D G3DSA:1.10.10.10 2 80 1.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34015 7390efc6954b7fa389fe4a40a5000db3 239 SMART SM00345 20 78 1.2E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS33905 990313f1370d4d9e5ec9936e20479dc6 147 Pfam PF11292 Protein of unknown function (DUF3093) 4 142 2.1E-30 T 28-03-2018 IPR021443 Protein of unknown function DUF3093 SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 Gene3D G3DSA:3.30.110.40 384 458 6.6E-15 T 28-03-2018 IPR001455 TusA-like domain SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 Pfam PF00266 Aminotransferase class-V 3 358 8.3E-42 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 SUPERFAMILY SSF64307 388 457 4.06E-15 T 28-03-2018 IPR001455 TusA-like domain SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 Pfam PF01206 Sulfurtransferase TusA 389 456 8.5E-14 T 28-03-2018 IPR001455 TusA-like domain SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 Gene3D G3DSA:3.90.1150.10 258 373 3.5E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 390 414 - T 28-03-2018 IPR001455 TusA-like domain SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 Gene3D G3DSA:3.40.640.10 10 251 9.2E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 SUPERFAMILY SSF53383 3 366 1.73E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS11415 4839b00db5bc991c05c21d509e019843 459 PIRSF PIRSF005572 1 373 9.9E-130 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 Gene3D G3DSA:1.25.40.10 97 270 5.6E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 SMART SM00862 16 88 1.5E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 SUPERFAMILY SSF52540 275 554 8.15E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 Gene3D G3DSA:1.10.10.10 6 96 2.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 Gene3D G3DSA:1.25.40.10 755 1095 2.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 SMART SM01043 95 241 1.5E-39 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 Gene3D G3DSA:3.40.50.300 271 425 5.7E-10 T 28-03-2018 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 SUPERFAMILY SSF48452 852 984 5.88E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 SUPERFAMILY SSF46894 2 87 7.09E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 SUPERFAMILY SSF48452 90 253 1.86E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 76 2.5E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19655 48ee1c13fad6777958df35b53097b826 1110 Pfam PF03704 Bacterial transcriptional activator domain 95 241 2.3E-35 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS33645 c7d680c19d42c89cce40344548d85704 329 PIRSF PIRSF001439 15 329 1.7E-62 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMD44_RS33645 c7d680c19d42c89cce40344548d85704 329 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 26 326 1.2E-48 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMD44_RS33645 c7d680c19d42c89cce40344548d85704 329 Gene3D G3DSA:3.30.1780.10 18 151 1.1E-41 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMD44_RS33645 c7d680c19d42c89cce40344548d85704 329 SUPERFAMILY SSF51735 21 328 2.03E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS33645 c7d680c19d42c89cce40344548d85704 329 Gene3D G3DSA:3.40.50.720 152 308 1.1E-22 T 28-03-2018 SMD44_RS37235 56f9261523c749b11c99ad9ffbefe12c 303 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS37235 56f9261523c749b11c99ad9ffbefe12c 303 Pfam PF00005 ABC transporter 18 157 5.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS37235 56f9261523c749b11c99ad9ffbefe12c 303 SUPERFAMILY SSF52540 2 213 3.83E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37235 56f9261523c749b11c99ad9ffbefe12c 303 SMART SM00382 26 205 3.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS37235 56f9261523c749b11c99ad9ffbefe12c 303 Gene3D G3DSA:3.40.50.300 1 238 1.0E-57 T 28-03-2018 SMD44_RS16570 74003a112284feb20517bcdb2407a69b 496 Gene3D G3DSA:1.20.1250.20 286 492 2.8E-10 T 28-03-2018 SMD44_RS16570 74003a112284feb20517bcdb2407a69b 496 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 492 6.7E-185 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 SMD44_RS16570 74003a112284feb20517bcdb2407a69b 496 Gene3D G3DSA:1.20.1250.20 15 214 3.8E-23 T 28-03-2018 SMD44_RS16570 74003a112284feb20517bcdb2407a69b 496 Pfam PF00854 POT family 94 457 3.6E-62 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 SMD44_RS16570 74003a112284feb20517bcdb2407a69b 496 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 156 168 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 SMD44_RS16570 74003a112284feb20517bcdb2407a69b 496 SUPERFAMILY SSF103473 23 221 1.48E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS16570 74003a112284feb20517bcdb2407a69b 496 SUPERFAMILY SSF103473 274 489 1.48E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS19790 433396993a97af5662aff6f9f7c7f0d7 202 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 40 183 8.0E-33 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like SMD44_RS19790 433396993a97af5662aff6f9f7c7f0d7 202 SUPERFAMILY SSF56784 22 188 4.81E-22 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS19790 433396993a97af5662aff6f9f7c7f0d7 202 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 69 173 1.4E-18 T 28-03-2018 SMD44_RS19790 433396993a97af5662aff6f9f7c7f0d7 202 Gene3D G3DSA:3.40.50.1000 50 198 7.3E-18 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS19790 433396993a97af5662aff6f9f7c7f0d7 202 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 171 9.8E-25 T 28-03-2018 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 SUPERFAMILY SSF53901 267 388 1.01E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 PIRSF PIRSF000429 2 389 1.2E-110 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 Gene3D G3DSA:3.40.47.10 2 261 4.7E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 Gene3D G3DSA:3.40.47.10 262 389 1.0E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 Pfam PF02803 Thiolase, C-terminal domain 267 388 4.0E-41 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 Pfam PF00108 Thiolase, N-terminal domain 6 257 8.5E-51 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 387 4.5E-113 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS12455 28c22a586d954008850a90e9fef30c3b 389 SUPERFAMILY SSF53901 5 266 4.01E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36340 5a815f4cd3f8cbc088da84d173f34727 277 Gene3D G3DSA:1.10.3720.10 1 264 1.1E-41 T 28-03-2018 SMD44_RS36340 5a815f4cd3f8cbc088da84d173f34727 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 270 1.7E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS36340 5a815f4cd3f8cbc088da84d173f34727 277 SUPERFAMILY SSF161098 11 277 1.21E-70 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS03030 14b3b7f955e498f1f90cb007ae955225 401 Gene3D G3DSA:3.40.710.10 54 348 1.6E-47 T 28-03-2018 SMD44_RS03030 14b3b7f955e498f1f90cb007ae955225 401 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 71 298 1.7E-34 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD44_RS03030 14b3b7f955e498f1f90cb007ae955225 401 SUPERFAMILY SSF56601 72 317 8.62E-53 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS03030 14b3b7f955e498f1f90cb007ae955225 401 SUPERFAMILY SSF56601 20 42 8.62E-53 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 5.6E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 285 5.6E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 5.6E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 5.6E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 13 35 5.6E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 Pfam PF14759 Reductase C-terminal 322 405 1.6E-24 T 28-03-2018 IPR028202 Reductase, C-terminal SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 SUPERFAMILY SSF51905 9 283 2.78E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 Gene3D G3DSA:3.50.50.60 104 235 1.9E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 Gene3D G3DSA:3.50.50.60 243 319 2.8E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 SUPERFAMILY SSF55424 316 405 9.61E-26 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 Gene3D G3DSA:3.30.390.30 320 407 3.0E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 2.5E-26 T 28-03-2018 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 2.5E-26 T 28-03-2018 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 2.5E-26 T 28-03-2018 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 2.5E-26 T 28-03-2018 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.5E-26 T 28-03-2018 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 300 2.9E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11155 e9813a7b375a74881467a047ff2d9873 407 Gene3D G3DSA:3.50.50.60 2 103 5.7E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03845 2eb7c69b2c2bbd720cd68eac4c990c14 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS03845 2eb7c69b2c2bbd720cd68eac4c990c14 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS03845 2eb7c69b2c2bbd720cd68eac4c990c14 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS03845 2eb7c69b2c2bbd720cd68eac4c990c14 193 Gene3D G3DSA:1.10.10.60 1 61 9.7E-22 T 28-03-2018 SMD44_RS03845 2eb7c69b2c2bbd720cd68eac4c990c14 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 3.4E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS03845 2eb7c69b2c2bbd720cd68eac4c990c14 193 SUPERFAMILY SSF46689 7 79 9.23E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS03845 2eb7c69b2c2bbd720cd68eac4c990c14 193 Gene3D G3DSA:1.10.357.10 62 190 2.1E-18 T 28-03-2018 SMD44_RS43160 a05cdc871d7996055663618130d5180a 434 SUPERFAMILY SSF52540 273 373 9.74E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43160 a05cdc871d7996055663618130d5180a 434 SUPERFAMILY SSF52540 69 108 9.74E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43160 a05cdc871d7996055663618130d5180a 434 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 69 360 6.7E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS43160 a05cdc871d7996055663618130d5180a 434 Gene3D G3DSA:3.40.50.300 63 380 4.6E-8 T 28-03-2018 SMD44_RS25650 adb21ec91ec474ee07855303af5eabe7 288 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 259 30.707 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS25650 adb21ec91ec474ee07855303af5eabe7 288 Pfam PF01416 tRNA pseudouridine synthase 18 117 2.0E-6 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS25650 adb21ec91ec474ee07855303af5eabe7 288 Pfam PF01416 tRNA pseudouridine synthase 158 260 6.2E-24 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS25650 adb21ec91ec474ee07855303af5eabe7 288 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 253 2.1E-49 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS25650 adb21ec91ec474ee07855303af5eabe7 288 PIRSF PIRSF001430 10 276 1.1E-72 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS25650 adb21ec91ec474ee07855303af5eabe7 288 Gene3D G3DSA:3.30.70.660 120 258 1.1E-29 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS25650 adb21ec91ec474ee07855303af5eabe7 288 Gene3D G3DSA:3.30.70.580 9 119 2.7E-33 T 28-03-2018 SMD44_RS25650 adb21ec91ec474ee07855303af5eabe7 288 SUPERFAMILY SSF55120 9 266 6.19E-71 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS02490 1c6e916707fd3b08eacc7a9c4e9e1604 375 Gene3D G3DSA:1.20.1250.20 181 371 3.5E-14 T 28-03-2018 SMD44_RS02490 1c6e916707fd3b08eacc7a9c4e9e1604 375 Gene3D G3DSA:1.20.1250.20 2 174 2.9E-11 T 28-03-2018 SMD44_RS02490 1c6e916707fd3b08eacc7a9c4e9e1604 375 Pfam PF07690 Major Facilitator Superfamily 8 329 2.6E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS02490 1c6e916707fd3b08eacc7a9c4e9e1604 375 SUPERFAMILY SSF103473 10 364 3.27E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 Gene3D G3DSA:3.40.50.2300 6 138 2.5E-34 T 28-03-2018 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 Gene3D G3DSA:1.10.10.10 139 216 8.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 Pfam PF00072 Response regulator receiver domain 9 120 1.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 SUPERFAMILY SSF46894 152 214 6.12E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 SUPERFAMILY SSF52172 6 136 8.54E-30 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 SMART SM00448 7 120 5.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 SMART SM00421 154 211 1.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21810 c44b9a403fda99fb26c7eb13c950bd9b 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 1.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS30595 8a307011395f005b27670924bb9a8428 360 Gene3D G3DSA:3.40.190.10 20 153 5.7E-13 T 28-03-2018 SMD44_RS30595 8a307011395f005b27670924bb9a8428 360 Pfam PF13343 Bacterial extracellular solute-binding protein 85 321 2.5E-19 T 28-03-2018 SMD44_RS30595 8a307011395f005b27670924bb9a8428 360 SUPERFAMILY SSF53850 38 355 1.53E-50 T 28-03-2018 SMD44_RS30595 8a307011395f005b27670924bb9a8428 360 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 36 354 3.3E-71 T 28-03-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030288|GO:0030975 SMD44_RS30595 8a307011395f005b27670924bb9a8428 360 Gene3D G3DSA:3.40.190.10 154 356 4.3E-29 T 28-03-2018 SMD44_RS43595 fe678ca7217ca26914a9b9ccfb31d25a 103 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 4 89 2.8E-32 T 28-03-2018 IPR010152 CRISPR-associated protein Cas2 subtype SMD44_RS43595 fe678ca7217ca26914a9b9ccfb31d25a 103 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 4 89 2.4E-20 T 28-03-2018 IPR010152 CRISPR-associated protein Cas2 subtype SMD44_RS00050 dfe2884c9966f8225405953bc41a83e9 592 Gene3D G3DSA:1.10.443.10 92 420 8.9E-10 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS00050 dfe2884c9966f8225405953bc41a83e9 592 SUPERFAMILY SSF56349 241 400 5.0E-8 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS08725 c946bff2bc004009f9c869dfab04c098 267 Pfam PF01522 Polysaccharide deacetylase 62 192 4.1E-31 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS08725 c946bff2bc004009f9c869dfab04c098 267 Gene3D G3DSA:3.20.20.370 11 224 1.1E-47 T 28-03-2018 SMD44_RS08725 c946bff2bc004009f9c869dfab04c098 267 SUPERFAMILY SSF88713 24 192 3.21E-39 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS16765 86f8301ec302f4e0722c469cc49d5f0e 438 Pfam PF02353 Mycolic acid cyclopropane synthetase 140 410 7.4E-96 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS16765 86f8301ec302f4e0722c469cc49d5f0e 438 Gene3D G3DSA:3.40.50.150 136 414 7.4E-71 T 28-03-2018 SMD44_RS16765 86f8301ec302f4e0722c469cc49d5f0e 438 SUPERFAMILY SSF53335 148 414 2.43E-83 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS16765 86f8301ec302f4e0722c469cc49d5f0e 438 PIRSF PIRSF003085 4 431 3.5E-138 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 SMD44_RS16765 86f8301ec302f4e0722c469cc49d5f0e 438 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 157 416 1.1E-4 T 28-03-2018 IPR020803 Polyketide synthase, methyltransferase domain SMD44_RS36020 fbcc8e94adc14ee3a34409d011466b90 462 Pfam PF07690 Major Facilitator Superfamily 41 367 3.4E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS36020 fbcc8e94adc14ee3a34409d011466b90 462 SUPERFAMILY SSF103473 35 416 1.57E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS36020 fbcc8e94adc14ee3a34409d011466b90 462 Gene3D G3DSA:1.20.1250.20 234 421 3.0E-7 T 28-03-2018 SMD44_RS36020 fbcc8e94adc14ee3a34409d011466b90 462 Gene3D G3DSA:1.20.1250.20 30 223 3.8E-11 T 28-03-2018 SMD44_RS08190 256fd5a7d0de2109394fd0480752fd4e 618 Gene3D G3DSA:3.10.580.10 487 615 1.1E-11 T 28-03-2018 SMD44_RS08190 256fd5a7d0de2109394fd0480752fd4e 618 SUPERFAMILY SSF54631 495 612 6.59E-11 T 28-03-2018 SMD44_RS08190 256fd5a7d0de2109394fd0480752fd4e 618 Pfam PF02163 Peptidase family M50 374 422 2.0E-7 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 SMD44_RS11760 96c81e8e222069f0392cbbdfd3c5054d 345 Pfam PF00120 Glutamine synthetase, catalytic domain 95 238 1.2E-11 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11760 96c81e8e222069f0392cbbdfd3c5054d 345 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 84 1.4E-14 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11760 96c81e8e222069f0392cbbdfd3c5054d 345 SMART SM01230 91 335 1.1E-47 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11760 96c81e8e222069f0392cbbdfd3c5054d 345 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 221 237 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMD44_RS11760 96c81e8e222069f0392cbbdfd3c5054d 345 Gene3D G3DSA:3.30.590.10 81 344 3.2E-59 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD44_RS11760 96c81e8e222069f0392cbbdfd3c5054d 345 ProSitePatterns PS00180 Glutamine synthetase signature 1. 43 60 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMD44_RS11760 96c81e8e222069f0392cbbdfd3c5054d 345 SUPERFAMILY SSF54368 7 90 2.49E-12 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11760 96c81e8e222069f0392cbbdfd3c5054d 345 SUPERFAMILY SSF55931 93 340 1.77E-62 T 28-03-2018 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 Pfam PF00890 FAD binding domain 47 452 4.2E-59 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 416 438 9.1E-7 T 28-03-2018 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 47 66 9.1E-7 T 28-03-2018 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 SUPERFAMILY SSF56425 272 414 2.39E-33 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 SUPERFAMILY SSF51905 40 288 2.56E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 SUPERFAMILY SSF51905 417 468 2.56E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 47 648 0.0 T 28-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 Pfam PF02910 Fumarate reductase flavoprotein C-term 514 648 8.3E-35 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 Gene3D G3DSA:3.50.50.60 38 500 2.9E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 Gene3D G3DSA:1.20.58.100 501 602 2.5E-24 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS37370 d50854d81c4881045b16de6086f30645 649 SUPERFAMILY SSF46977 505 648 9.68E-40 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 SUPERFAMILY SSF63737 3 189 1.27E-35 T 28-03-2018 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 Pfam PF01433 Peptidase family M1 domain 217 438 3.7E-56 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 4 828 0.0 T 28-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 Gene3D G3DSA:1.10.390.10 273 442 6.5E-44 T 28-03-2018 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 129 144 2.8E-21 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 253 263 2.8E-21 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 172 187 2.8E-21 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 306 318 2.8E-21 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 287 302 2.8E-21 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 Pfam PF11838 ERAP1-like C-terminal domain 513 823 3.9E-44 T 28-03-2018 IPR024571 ERAP1-like C-terminal domain SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 Gene3D G3DSA:2.60.40.1730 4 190 5.0E-31 T 28-03-2018 SMD44_RS10610 0132b27b070802ff0f01494882b6f37a 834 SUPERFAMILY SSF55486 196 445 5.37E-70 T 28-03-2018 SMD44_RS33890 5efe7abd7b06c2e7d47c5f2cf578dcf2 210 SUPERFAMILY SSF56281 3 60 3.22E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS33890 5efe7abd7b06c2e7d47c5f2cf578dcf2 210 SUPERFAMILY SSF56281 87 180 3.22E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS33890 5efe7abd7b06c2e7d47c5f2cf578dcf2 210 Gene3D G3DSA:3.60.15.10 1 177 1.8E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS33890 5efe7abd7b06c2e7d47c5f2cf578dcf2 210 Pfam PF13483 Beta-lactamase superfamily domain 2 175 1.9E-22 T 28-03-2018 SMD44_RS33890 5efe7abd7b06c2e7d47c5f2cf578dcf2 210 SMART SM00849 7 175 0.0057 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS31840 924ebf87cf5e7df9e2bcecf67d2e0da5 184 SUPERFAMILY SSF50475 11 166 4.91E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS31840 924ebf87cf5e7df9e2bcecf67d2e0da5 184 SMART SM00903 18 164 6.3E-42 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS31840 924ebf87cf5e7df9e2bcecf67d2e0da5 184 Pfam PF01613 Flavin reductase like domain 18 164 2.8E-33 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS31840 924ebf87cf5e7df9e2bcecf67d2e0da5 184 Gene3D G3DSA:2.30.110.10 6 178 2.3E-43 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS31640 177ff2d621221c497f4875e31b926eab 93 SUPERFAMILY SSF55594 1 88 7.07E-19 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SMD44_RS31640 177ff2d621221c497f4875e31b926eab 93 Pfam PF00381 PTS HPr component phosphorylation site 3 83 9.2E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SMD44_RS31640 177ff2d621221c497f4875e31b926eab 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 4.5E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SMD44_RS31640 177ff2d621221c497f4875e31b926eab 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site SMD44_RS31640 177ff2d621221c497f4875e31b926eab 93 Gene3D G3DSA:3.30.1340.10 1 86 9.6E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SMD44_RS31640 177ff2d621221c497f4875e31b926eab 93 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.6E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SMD44_RS31640 177ff2d621221c497f4875e31b926eab 93 PRINTS PR00107 Phosphocarrier protein signature 39 54 1.6E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SMD44_RS31640 177ff2d621221c497f4875e31b926eab 93 PRINTS PR00107 Phosphocarrier protein signature 54 71 1.6E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like SMD44_RS06455 06bc97eaa21bfb490907850a71eac4c2 528 Gene3D G3DSA:3.40.190.10 189 289 7.0E-20 T 28-03-2018 SMD44_RS06455 06bc97eaa21bfb490907850a71eac4c2 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 443 5.6E-70 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS06455 06bc97eaa21bfb490907850a71eac4c2 528 SUPERFAMILY SSF53850 34 524 1.77E-96 T 28-03-2018 SMD44_RS06455 06bc97eaa21bfb490907850a71eac4c2 528 Gene3D G3DSA:3.90.76.10 46 188 1.8E-27 T 28-03-2018 SMD44_RS06455 06bc97eaa21bfb490907850a71eac4c2 528 PIRSF PIRSF002741 19 516 1.0E-66 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS06455 06bc97eaa21bfb490907850a71eac4c2 528 Gene3D G3DSA:3.10.105.10 290 495 1.9E-35 T 28-03-2018 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 SUPERFAMILY SSF88659 123 201 7.41E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 PRINTS PR00046 Major sigma-70 factor signature 244 259 4.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 PRINTS PR00046 Major sigma-70 factor signature 227 239 4.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 PRINTS PR00046 Major sigma-70 factor signature 77 90 4.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 PRINTS PR00046 Major sigma-70 factor signature 259 270 4.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 SUPERFAMILY SSF88659 188 276 8.04E-25 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 PIRSF PIRSF000770 26 277 1.2E-75 T 28-03-2018 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 Gene3D G3DSA:1.10.1740.10 35 120 1.2E-19 T 28-03-2018 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 SUPERFAMILY SSF88946 20 122 1.1E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 Gene3D G3DSA:1.10.10.10 196 278 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 Pfam PF04545 Sigma-70, region 4 223 272 9.8E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 274 5.5E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 244 270 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 Pfam PF04542 Sigma-70 region 2 50 122 2.3E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 50 274 5.1E-88 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 Pfam PF04539 Sigma-70 region 3 130 209 5.0E-8 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30550 80c01d238cd159c86a64831f26018a10 279 Gene3D G3DSA:1.10.10.10 123 171 4.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21100 96eb34c789059fea96b5dd15854ab617 444 Pfam PF02096 60Kd inner membrane protein 38 255 7.3E-59 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SMD44_RS21100 96eb34c789059fea96b5dd15854ab617 444 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 38 255 2.3E-62 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SMD44_RS29825 ae372f7a4640ad452471ec9c7bfefef0 98 SUPERFAMILY SSF141000 4 94 3.14E-27 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMD44_RS29825 ae372f7a4640ad452471ec9c7bfefef0 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.852 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMD44_RS29825 ae372f7a4640ad452471ec9c7bfefef0 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 91 2.3E-16 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMD44_RS29825 ae372f7a4640ad452471ec9c7bfefef0 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 3.0E-24 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMD44_RS19545 98adaf8587750bd785705dace495977c 182 SUPERFAMILY SSF46785 26 167 3.69E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19545 98adaf8587750bd785705dace495977c 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 5.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS19545 98adaf8587750bd785705dace495977c 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 5.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS19545 98adaf8587750bd785705dace495977c 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 5.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS19545 98adaf8587750bd785705dace495977c 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 5.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS19545 98adaf8587750bd785705dace495977c 182 Gene3D G3DSA:1.10.10.10 6 174 3.0E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19545 98adaf8587750bd785705dace495977c 182 Pfam PF12802 MarR family 55 114 6.5E-12 T 28-03-2018 SMD44_RS19545 98adaf8587750bd785705dace495977c 182 SMART SM00347 50 153 2.4E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Gene3D G3DSA:1.10.860.10 468 616 1.3E-10 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Gene3D G3DSA:3.40.1360.10 243 371 6.7E-31 T 28-03-2018 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 SMART SM00400 37 91 9.1E-32 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 PIRSF PIRSF002811 2 624 8.3E-168 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Pfam PF01807 CHC2 zinc finger 6 101 1.1E-31 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 SMART SM00766 483 613 2.2E-10 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Gene3D G3DSA:3.90.580.10 1 103 1.8E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 TIGRFAM TIGR01391 dnaG: DNA primase 5 420 3.2E-115 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Pfam PF13662 Toprim domain 262 332 3.9E-16 T 28-03-2018 IPR006171 TOPRIM domain SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Hamap MF_00974 DNA primase [dnaG]. 4 617 26.502 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 253 4.8E-37 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Gene3D G3DSA:1.20.50.20 372 425 4.8E-15 T 28-03-2018 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 SUPERFAMILY SSF56731 117 428 1.65E-94 T 28-03-2018 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Gene3D G3DSA:3.90.980.10 110 242 4.4E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Pfam PF10410 DnaB-helicase binding domain of primase 373 426 1.2E-13 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 SUPERFAMILY SSF57783 4 102 3.91E-32 T 28-03-2018 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 Pfam PF08278 DNA primase DnaG DnaB-binding 484 593 3.7E-10 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 SMD44_RS13330 b016bdd362a964b16c106a3205491f68 634 SMART SM00493 261 337 3.5E-16 T 28-03-2018 IPR006171 TOPRIM domain SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 SMART SM00191 344 402 4.3E-5 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 SMART SM00191 102 158 0.05 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 SMART SM00191 164 246 53.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 SMART SM00191 273 332 6.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 SMART SM00191 36 94 93.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 SMART SM00191 416 469 3.4 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 114 187 4.2E-6 T 28-03-2018 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Gene3D G3DSA:2.60.40.680 360 425 6.9E-14 T 28-03-2018 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Gene3D G3DSA:2.60.40.680 278 359 1.5E-14 T 28-03-2018 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Gene3D G3DSA:2.60.40.680 21 120 1.6E-13 T 28-03-2018 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Gene3D G3DSA:2.60.40.680 426 487 3.0E-5 T 28-03-2018 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Gene3D G3DSA:2.60.40.680 205 277 0.01 T 28-03-2018 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Gene3D G3DSA:2.60.40.680 121 195 2.4E-15 T 28-03-2018 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Pfam PF01839 FG-GAP repeat 45 75 1.5E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 Pfam PF01839 FG-GAP repeat 348 386 5.7E-7 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 PRINTS PR01185 Integrin alpha subunit signature 99 119 9.8E-6 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 PRINTS PR01185 Integrin alpha subunit signature 224 245 9.8E-6 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 PRINTS PR01185 Integrin alpha subunit signature 61 73 9.8E-6 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 PRINTS PR01185 Integrin alpha subunit signature 166 190 9.8E-6 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS22425 576ccd0eabdf6c049c5055b72aaaa997 489 SUPERFAMILY SSF69318 44 393 4.4E-42 T 28-03-2018 SMD44_RS24445 0f2114d7f3b216495070c33b27132d20 321 Gene3D G3DSA:3.10.129.10 177 296 4.6E-19 T 28-03-2018 SMD44_RS24445 0f2114d7f3b216495070c33b27132d20 321 SUPERFAMILY SSF54637 181 290 1.32E-19 T 28-03-2018 IPR029069 HotDog domain SMD44_RS24445 0f2114d7f3b216495070c33b27132d20 321 Gene3D G3DSA:3.10.129.10 30 176 4.4E-26 T 28-03-2018 SMD44_RS24445 0f2114d7f3b216495070c33b27132d20 321 Pfam PF01575 MaoC like domain 179 234 1.2E-12 T 28-03-2018 IPR002539 MaoC-like domain SMD44_RS24445 0f2114d7f3b216495070c33b27132d20 321 SUPERFAMILY SSF54637 50 178 3.36E-9 T 28-03-2018 IPR029069 HotDog domain SMD44_RS31520 cea67733e56c14bc72572071725b84b7 754 SUPERFAMILY SSF52540 17 217 8.26E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31520 cea67733e56c14bc72572071725b84b7 754 Gene3D G3DSA:3.40.50.300 8 233 6.4E-34 T 28-03-2018 SMD44_RS31520 cea67733e56c14bc72572071725b84b7 754 Pfam PF00005 ABC transporter 20 155 5.6E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS11160 783cb9a012e9595fc7fbf50a97f8066e 440 SUPERFAMILY SSF54373 264 356 3.27E-21 T 28-03-2018 SMD44_RS11160 783cb9a012e9595fc7fbf50a97f8066e 440 Gene3D G3DSA:3.30.9.10 130 210 1.0E-8 T 28-03-2018 SMD44_RS11160 783cb9a012e9595fc7fbf50a97f8066e 440 Gene3D G3DSA:3.30.9.10 211 357 4.5E-28 T 28-03-2018 SMD44_RS11160 783cb9a012e9595fc7fbf50a97f8066e 440 SUPERFAMILY SSF51905 358 415 7.12E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11160 783cb9a012e9595fc7fbf50a97f8066e 440 SUPERFAMILY SSF51905 44 263 7.12E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11160 783cb9a012e9595fc7fbf50a97f8066e 440 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 45 400 9.3E-122 T 28-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 SMD44_RS11160 783cb9a012e9595fc7fbf50a97f8066e 440 Pfam PF01266 FAD dependent oxidoreductase 44 395 1.6E-66 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS11160 783cb9a012e9595fc7fbf50a97f8066e 440 Gene3D G3DSA:3.50.50.60 15 115 1.9E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS23735 c2c0da3ed7653290b0d37e9da506b80c 292 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 21 36 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS23735 c2c0da3ed7653290b0d37e9da506b80c 292 SUPERFAMILY SSF51717 19 283 3.66E-92 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS23735 c2c0da3ed7653290b0d37e9da506b80c 292 Gene3D G3DSA:3.20.20.20 11 291 2.5E-102 T 28-03-2018 SMD44_RS23735 c2c0da3ed7653290b0d37e9da506b80c 292 Pfam PF00809 Pterin binding enzyme 22 267 2.9E-84 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS23735 c2c0da3ed7653290b0d37e9da506b80c 292 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 281 1.5E-90 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 SMD44_RS23735 c2c0da3ed7653290b0d37e9da506b80c 292 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 55 68 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS36415 dd8855e49bfac42a363d78dbdf60a44a 272 SMART SM00862 27 107 4.9E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS36415 dd8855e49bfac42a363d78dbdf60a44a 272 Pfam PF00486 Transcriptional regulatory protein, C terminal 35 107 5.4E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS36415 dd8855e49bfac42a363d78dbdf60a44a 272 SUPERFAMILY SSF46894 14 107 4.54E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS36415 dd8855e49bfac42a363d78dbdf60a44a 272 Pfam PF03704 Bacterial transcriptional activator domain 114 260 2.5E-35 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS36415 dd8855e49bfac42a363d78dbdf60a44a 272 SMART SM01043 114 260 1.2E-32 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS36415 dd8855e49bfac42a363d78dbdf60a44a 272 Gene3D G3DSA:1.25.40.10 111 267 1.5E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36415 dd8855e49bfac42a363d78dbdf60a44a 272 SUPERFAMILY SSF48452 111 265 8.35E-32 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36415 dd8855e49bfac42a363d78dbdf60a44a 272 Gene3D G3DSA:1.10.10.10 3 110 1.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12740 aed85b797acbf5de13af90c72dc71274 151 Gene3D G3DSA:1.10.1660.10 35 93 6.4E-18 T 28-03-2018 SMD44_RS12740 aed85b797acbf5de13af90c72dc71274 151 Gene3D G3DSA:1.10.1660.10 94 151 8.7E-14 T 28-03-2018 SMD44_RS12740 aed85b797acbf5de13af90c72dc71274 151 Pfam PF13411 MerR HTH family regulatory protein 39 100 1.6E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS12740 aed85b797acbf5de13af90c72dc71274 151 SUPERFAMILY SSF46955 39 150 1.79E-28 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS12740 aed85b797acbf5de13af90c72dc71274 151 SMART SM00422 39 108 3.8E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS25695 804fa3437b57afad47c2802723def364 122 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 122 21.52 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD44_RS25695 804fa3437b57afad47c2802723def364 122 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 121 8.8E-20 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD44_RS25695 804fa3437b57afad47c2802723def364 122 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 83 4.0E-8 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD44_RS25695 804fa3437b57afad47c2802723def364 122 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 100 1.8E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS25695 804fa3437b57afad47c2802723def364 122 Gene3D G3DSA:3.90.470.20 1 122 2.0E-28 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS25695 804fa3437b57afad47c2802723def364 122 SUPERFAMILY SSF56214 2 121 1.57E-23 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS25695 804fa3437b57afad47c2802723def364 122 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 120 2.1E-22 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD44_RS34990 6a59e4e697aba30a1bd5b7594bb4b512 751 Gene3D G3DSA:3.40.50.300 40 189 8.7E-9 T 28-03-2018 SMD44_RS34990 6a59e4e697aba30a1bd5b7594bb4b512 751 SUPERFAMILY SSF48452 617 738 4.3E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34990 6a59e4e697aba30a1bd5b7594bb4b512 751 SUPERFAMILY SSF52540 73 310 2.42E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34990 6a59e4e697aba30a1bd5b7594bb4b512 751 SMART SM00028 700 733 33.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS34990 6a59e4e697aba30a1bd5b7594bb4b512 751 SMART SM00028 578 611 0.11 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS34990 6a59e4e697aba30a1bd5b7594bb4b512 751 SMART SM00028 660 693 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS34990 6a59e4e697aba30a1bd5b7594bb4b512 751 SUPERFAMILY SSF48452 534 649 9.49E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34990 6a59e4e697aba30a1bd5b7594bb4b512 751 Gene3D G3DSA:1.25.40.10 512 750 1.5E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS05870 2031578d9ee30829c9b3d5dd0182ed01 297 Gene3D G3DSA:3.20.20.30 14 294 6.3E-55 T 28-03-2018 SMD44_RS05870 2031578d9ee30829c9b3d5dd0182ed01 297 Pfam PF00296 Luciferase-like monooxygenase 24 239 1.5E-30 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS05870 2031578d9ee30829c9b3d5dd0182ed01 297 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 6 295 6.1E-111 T 28-03-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted SMD44_RS05870 2031578d9ee30829c9b3d5dd0182ed01 297 SUPERFAMILY SSF51679 5 291 9.27E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS26440 63bf38a800a0147e041ed5bb50860e2a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 7.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS26440 63bf38a800a0147e041ed5bb50860e2a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 7.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS26440 63bf38a800a0147e041ed5bb50860e2a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS26440 63bf38a800a0147e041ed5bb50860e2a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 7.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS26440 63bf38a800a0147e041ed5bb50860e2a 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS26440 63bf38a800a0147e041ed5bb50860e2a 251 Gene3D G3DSA:3.40.50.720 4 233 1.2E-34 T 28-03-2018 SMD44_RS26440 63bf38a800a0147e041ed5bb50860e2a 251 SUPERFAMILY SSF51735 11 249 8.14E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS26440 63bf38a800a0147e041ed5bb50860e2a 251 Pfam PF00106 short chain dehydrogenase 11 200 3.0E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS26895 e92804c3ad5ead7a0bd076663457b834 486 Pfam PF00171 Aldehyde dehydrogenase family 41 485 1.7E-166 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS26895 e92804c3ad5ead7a0bd076663457b834 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS26895 e92804c3ad5ead7a0bd076663457b834 486 Gene3D G3DSA:3.40.309.10 285 475 9.5E-69 T 28-03-2018 SMD44_RS26895 e92804c3ad5ead7a0bd076663457b834 486 Gene3D G3DSA:3.40.605.10 25 284 3.6E-102 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS26895 e92804c3ad5ead7a0bd076663457b834 486 SUPERFAMILY SSF53720 28 485 1.96E-164 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS17225 c0f6ae47e170e0a1505438ee5616e79d 516 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 2.1E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS17225 c0f6ae47e170e0a1505438ee5616e79d 516 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 172 196 2.1E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS17225 c0f6ae47e170e0a1505438ee5616e79d 516 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 141 2.1E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS17225 c0f6ae47e170e0a1505438ee5616e79d 516 SUPERFAMILY SSF51905 275 471 3.56E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17225 c0f6ae47e170e0a1505438ee5616e79d 516 Gene3D G3DSA:3.50.50.60 166 492 2.5E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17225 c0f6ae47e170e0a1505438ee5616e79d 516 SUPERFAMILY SSF51905 9 228 1.94E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17225 c0f6ae47e170e0a1505438ee5616e79d 516 Gene3D G3DSA:3.50.50.60 9 165 1.4E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17225 c0f6ae47e170e0a1505438ee5616e79d 516 Pfam PF00743 Flavin-binding monooxygenase-like 11 345 7.5E-20 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SUPERFAMILY SSF52777 1376 1619 5.45E-53 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:3.30.559.10 644 888 1.3E-19 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:3.30.559.10 1172 1387 3.8E-38 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Pfam PF00550 Phosphopantetheine attachment site 575 635 4.0E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Pfam PF00550 Phosphopantetheine attachment site 2164 2224 1.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:1.10.1200.10 2166 2240 4.8E-23 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:1.10.1200.10 576 643 1.6E-23 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SUPERFAMILY SSF52777 654 893 1.33E-19 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SUPERFAMILY SSF52777 1193 1390 2.22E-39 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:3.40.50.980 41 199 8.7E-48 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:2.30.38.10 1962 2043 4.9E-21 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1017 1185 2.5E-31 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 ProSitePatterns PS00012 Phosphopantetheine attachment site. 596 611 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:3.40.50.980 1805 1949 3.3E-31 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 548 1.1E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Pfam PF13193 AMP-binding enzyme C-terminal domain 2061 2138 3.8E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:3.40.50.980 1648 1804 4.8E-47 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1676 2077 6.6E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 70 472 5.6E-131 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SUPERFAMILY SSF47336 564 634 6.28E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Pfam PF00668 Condensation domain 1196 1636 5.5E-82 T 28-03-2018 IPR001242 Condensation domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Pfam PF00668 Condensation domain 814 1074 1.3E-28 T 28-03-2018 IPR001242 Condensation domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1802 1813 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SUPERFAMILY SSF56801 25 585 2.09E-151 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Pfam PF00501 AMP-binding enzyme 49 448 4.5E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Pfam PF00501 AMP-binding enzyme 1655 2053 2.4E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:3.40.50.980 200 355 5.7E-34 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:3.30.300.30 2048 2165 2.8E-38 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:3.30.300.30 443 575 1.1E-37 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2186 2201 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 Gene3D G3DSA:2.30.38.10 358 441 1.4E-20 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SUPERFAMILY SSF56801 1614 2175 1.15E-142 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SUPERFAMILY SSF52777 882 1162 1.03E-25 T 28-03-2018 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SUPERFAMILY SSF47336 2154 2226 2.09E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SMART SM00823 Phosphopantetheine attachment site 2162 2231 0.0021 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS07125 0c40e53ed596385baf867c7e01aeb517 2254 SMART SM00823 Phosphopantetheine attachment site 572 640 1.8E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS33310 3059c4bea2d4c016f18923f40bb5c583 239 Gene3D G3DSA:1.10.260.40 45 96 7.7E-9 T 28-03-2018 SMD44_RS33310 3059c4bea2d4c016f18923f40bb5c583 239 Gene3D G3DSA:1.10.10.60 1 44 1.9E-12 T 28-03-2018 SMD44_RS33310 3059c4bea2d4c016f18923f40bb5c583 239 SUPERFAMILY SSF48498 88 233 8.12E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS33310 3059c4bea2d4c016f18923f40bb5c583 239 SUPERFAMILY SSF46689 12 78 1.18E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS33310 3059c4bea2d4c016f18923f40bb5c583 239 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 230 2.3E-11 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS33310 3059c4bea2d4c016f18923f40bb5c583 239 Gene3D G3DSA:1.10.357.10 97 236 1.7E-25 T 28-03-2018 SMD44_RS33310 3059c4bea2d4c016f18923f40bb5c583 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 66 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06510 ce5232835329b72106b170c6aa6c926a 446 Pfam PF00155 Aminotransferase class I and II 98 430 2.6E-20 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS06510 ce5232835329b72106b170c6aa6c926a 446 Gene3D G3DSA:1.10.10.10 9 82 2.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06510 ce5232835329b72106b170c6aa6c926a 446 Gene3D G3DSA:3.40.640.10 111 308 2.9E-22 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS06510 ce5232835329b72106b170c6aa6c926a 446 SUPERFAMILY SSF53383 70 434 1.42E-55 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS06510 ce5232835329b72106b170c6aa6c926a 446 Gene3D G3DSA:3.90.1150.10 309 436 3.3E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS06510 ce5232835329b72106b170c6aa6c926a 446 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.4E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06510 ce5232835329b72106b170c6aa6c926a 446 SMART SM00345 15 74 4.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06510 ce5232835329b72106b170c6aa6c926a 446 SUPERFAMILY SSF46785 13 78 2.94E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28035 fc73b4b5c5da45fe101a3567b09175a4 392 Gene3D G3DSA:3.40.250.10 266 389 5.3E-24 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS28035 fc73b4b5c5da45fe101a3567b09175a4 392 SMART SM00450 290 387 2.5E-23 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS28035 fc73b4b5c5da45fe101a3567b09175a4 392 SUPERFAMILY SSF69572 7 357 6.93E-108 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD44_RS28035 fc73b4b5c5da45fe101a3567b09175a4 392 Gene3D G3DSA:3.40.50.720 10 259 1.8E-78 T 28-03-2018 SMD44_RS28035 fc73b4b5c5da45fe101a3567b09175a4 392 Pfam PF00899 ThiF family 21 254 1.3E-66 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD44_RS28035 fc73b4b5c5da45fe101a3567b09175a4 392 Pfam PF00581 Rhodanese-like domain 290 383 4.2E-13 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS26770 6e7e2e8e7cf25d08005202728ca19703 350 Gene3D G3DSA:3.40.50.2300 158 350 4.0E-40 T 28-03-2018 SMD44_RS26770 6e7e2e8e7cf25d08005202728ca19703 350 SUPERFAMILY SSF53822 53 296 3.81E-11 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS26770 6e7e2e8e7cf25d08005202728ca19703 350 Gene3D G3DSA:3.40.50.2300 38 157 5.4E-35 T 28-03-2018 SMD44_RS26770 6e7e2e8e7cf25d08005202728ca19703 350 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 47 340 2.8E-51 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 SUPERFAMILY SSF54631 1 137 8.42E-30 T 28-03-2018 SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 Gene3D G3DSA:3.10.580.10 70 198 2.9E-18 T 28-03-2018 SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 Pfam PF00571 CBS domain 1 48 6.6E-8 T 28-03-2018 IPR000644 CBS domain SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 Pfam PF00571 CBS domain 78 132 1.1E-13 T 28-03-2018 IPR000644 CBS domain SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 Gene3D G3DSA:3.10.580.10 1 69 8.1E-9 T 28-03-2018 SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 Pfam PF04972 BON domain 136 195 3.9E-9 T 28-03-2018 IPR007055 BON domain SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 PIRSF PIRSF036990 1 205 9.0E-59 T 28-03-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 SMART SM00116 85 133 7.7E-12 T 28-03-2018 IPR000644 CBS domain SMD44_RS39005 47ae602a8cd4bd53195b0e13a6fc1205 205 SMART SM00116 4 52 0.02 T 28-03-2018 IPR000644 CBS domain SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 382 1126 1.4E-143 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 Gene3D G3DSA:3.30.2080.10 970 1131 7.3E-61 T 28-03-2018 SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 Gene3D G3DSA:2.70.98.10 381 686 1.0E-81 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 Gene3D G3DSA:2.60.120.260 182 372 2.1E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 SUPERFAMILY SSF48208 624 1109 3.23E-15 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 Gene3D G3DSA:2.60.120.260 1132 1261 4.9E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 SUPERFAMILY SSF49785 79 186 6.66E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 Pfam PF07971 Glycosyl hydrolase family 92 600 1124 3.3E-150 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 Pfam PF00754 F5/8 type C domain 74 187 3.0E-11 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 Gene3D G3DSA:2.60.120.260 65 181 3.1E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS32260 b2ce772ecd75e4987ed36f0de0425f8c 1261 Gene3D G3DSA:1.20.1050.60 722 815 1.4E-28 T 28-03-2018 SMD44_RS04850 e9006415a6b6e7a322b89256ba2fbfad 262 PIRSF PIRSF000090 3 262 5.8E-83 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 SMD44_RS04850 e9006415a6b6e7a322b89256ba2fbfad 262 Pfam PF01012 Electron transfer flavoprotein domain 25 210 2.0E-44 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMD44_RS04850 e9006415a6b6e7a322b89256ba2fbfad 262 SMART SM00893 24 215 7.9E-56 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMD44_RS04850 e9006415a6b6e7a322b89256ba2fbfad 262 SUPERFAMILY SSF52402 3 258 8.84E-72 T 28-03-2018 SMD44_RS04850 e9006415a6b6e7a322b89256ba2fbfad 262 Gene3D G3DSA:3.40.50.620 3 262 1.1E-72 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS13940 0de8f20eb38dd2b84c8d936211d91ec1 575 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 292 408 4.6E-6 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS13940 0de8f20eb38dd2b84c8d936211d91ec1 575 Gene3D G3DSA:2.130.10.10 92 473 1.8E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS13940 0de8f20eb38dd2b84c8d936211d91ec1 575 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 489 575 1.2E-10 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 Gene3D G3DSA:1.10.10.60 2 60 2.4E-19 T 28-03-2018 SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 SUPERFAMILY SSF48498 107 200 1.94E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 Gene3D G3DSA:1.10.357.10 61 203 3.5E-22 T 28-03-2018 SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 SUPERFAMILY SSF46689 4 84 7.7E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 113 192 1.0E-7 T 28-03-2018 SMD44_RS05760 8a1f3cd5883c9bb8eceaa09cc58029f8 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.7E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM01294 2134 2201 3.4E-7 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF14765 Polyketide synthase dehydratase 3118 3386 1.5E-53 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.366.10 2934 3046 1.1E-32 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF52151 2936 3043 4.19E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF52151 2756 2877 4.19E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF52151 1237 1363 1.8E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF52151 1427 1523 1.8E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2160 2175 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4244 4259 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00826 3118 3279 9.0E-78 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.90.180.10 3862 3927 0.0015 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 719 969 3.3E-88 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2225 2475 4.8E-87 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.47.10 712 981 1.6E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.47.10 2227 2487 2.7E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.47.10 21 261 1.4E-4 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.90.180.10 3598 3737 9.9E-37 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF53901 715 1092 5.49E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2388 2404 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00107 Zinc-binding dehydrogenase 3741 3816 2.6E-8 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF47336 4209 4295 4.84E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00829 3602 3924 4.1E-130 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.366.10 443 565 1.1E-19 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.366.10 1419 1542 9.9E-31 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 882 898 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF50129 3604 3734 8.81E-25 T 28-03-2018 IPR011032 GroES-like SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00823 Phosphopantetheine attachment site 627 699 2.6E-21 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00823 Phosphopantetheine attachment site 4217 4289 1.4E-27 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00823 Phosphopantetheine attachment site 2133 2205 2.7E-33 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00698 Acyl transferase domain 2759 3051 2.8E-58 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00698 Acyl transferase domain 262 577 4.5E-66 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00698 Acyl transferase domain 1240 1552 2.1E-88 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF51735 3395 3581 3.9E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.47.10 984 1145 5.0E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.47.10 2490 2651 4.5E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3934 4112 1.4E-54 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1850 2030 1.8E-42 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF47336 2128 2240 4.45E-25 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.30.70.250 397 442 4.2E-12 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:1.10.1200.10 2126 2226 1.2E-21 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF51735 1640 1840 4.33E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00550 Phosphopantetheine attachment site 4219 4285 8.5E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00550 Phosphopantetheine attachment site 2135 2200 3.8E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF00550 Phosphopantetheine attachment site 630 695 1.1E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.10.129.10 3120 3246 5.7E-9 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00825 Beta-ketoacyl synthase 2227 2653 2.8E-202 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00825 Beta-ketoacyl synthase 721 1147 1.4E-224 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF53901 2222 2598 3.1E-99 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:1.10.1200.10 4185 4295 4.0E-17 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:1.10.1200.10 594 708 1.1E-14 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF55048 2882 2943 6.15E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF52151 260 388 7.85E-56 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF52151 451 547 7.85E-56 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3621 3676 1.8E-4 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.366.10 262 396 8.2E-39 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.366.10 2755 2893 4.4E-47 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.366.10 1237 1371 1.7E-41 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2759 3049 2.4E-124 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 263 559 1.6E-85 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1241 1535 3.7E-124 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF08659 KR domain 3936 4110 7.1E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF08659 KR domain 1850 2028 2.7E-55 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF55048 387 448 9.42E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2603 2722 2.0E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1097 1205 3.4E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.50.720 3738 3861 7.2E-14 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF51735 3701 3857 4.23E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.50.720 3928 4184 7.6E-45 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.40.50.720 1842 2102 1.4E-54 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF101166 4294 4344 9.42E-5 T 28-03-2018 IPR015357 Erythronolide synthase, docking KEGG: 00522+2.3.1.94|MetaCyc: PWY-7106 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2483 2600 4.5E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 977 1094 8.4E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF55048 1361 1426 2.88E-14 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.30.70.250 2894 2933 5.8E-17 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 Gene3D G3DSA:3.30.70.250 1372 1418 2.6E-19 T 28-03-2018 SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF47336 622 734 7.59E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF51735 3932 4130 2.48E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02305 fdf82561471453218f90edb03baae176 4369 SUPERFAMILY SSF51735 1847 2080 4.24E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 ProSitePatterns PS00622 LuxR-type HTH domain signature. 901 928 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 SUPERFAMILY SSF46894 882 938 2.41E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 Pfam PF13191 AAA ATPase domain 19 173 2.1E-17 T 28-03-2018 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 Gene3D G3DSA:1.10.10.10 898 941 6.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 Gene3D G3DSA:1.25.40.10 176 494 0.01 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 SMART SM00382 38 199 0.0022 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 Pfam PF00196 Bacterial regulatory proteins, luxR family 886 937 4.1E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 Gene3D G3DSA:1.25.40.10 583 897 3.2E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 SUPERFAMILY SSF52540 17 253 1.26E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 Gene3D G3DSA:3.40.50.300 11 175 3.1E-11 T 28-03-2018 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 887 901 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 901 917 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 917 929 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33230 ef0a87a905b4af24e9bb3550ff2d384b 943 SMART SM00421 884 941 9.0E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01490 e4371dd681da8f9f2b7c954f5f423d91 296 SUPERFAMILY SSF63380 29 147 6.27E-13 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS01490 e4371dd681da8f9f2b7c954f5f423d91 296 Gene3D G3DSA:2.40.30.10 29 146 2.7E-27 T 28-03-2018 SMD44_RS01490 e4371dd681da8f9f2b7c954f5f423d91 296 Pfam PF04954 Siderophore-interacting protein 155 274 1.7E-35 T 28-03-2018 IPR007037 Siderophore-interacting protein SMD44_RS01490 e4371dd681da8f9f2b7c954f5f423d91 296 Pfam PF08021 Siderophore-interacting FAD-binding domain 37 146 1.4E-25 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SMD44_RS01490 e4371dd681da8f9f2b7c954f5f423d91 296 Gene3D G3DSA:3.40.50.80 148 295 1.8E-40 T 28-03-2018 SMD44_RS28705 3a53df1d26d2d9f366a4ed28f3d4bae2 164 Pfam PF04978 Protein of unknown function (DUF664) 7 155 2.9E-41 T 28-03-2018 IPR007061 Protein of unknown function DUF664 SMD44_RS28705 3a53df1d26d2d9f366a4ed28f3d4bae2 164 Gene3D G3DSA:1.20.120.450 1 159 1.8E-30 T 28-03-2018 SMD44_RS28705 3a53df1d26d2d9f366a4ed28f3d4bae2 164 SUPERFAMILY SSF109854 2 154 1.18E-31 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS02185 c3f1c2adbbf318ceb46ba67193aaf923 287 Gene3D G3DSA:3.40.50.150 3 218 1.2E-27 T 28-03-2018 SMD44_RS02185 c3f1c2adbbf318ceb46ba67193aaf923 287 Pfam PF13649 Methyltransferase domain 47 139 2.0E-15 T 28-03-2018 SMD44_RS02185 c3f1c2adbbf318ceb46ba67193aaf923 287 SUPERFAMILY SSF53335 6 157 1.07E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS04070 4be8d61d722fb72847105e141afc60d2 399 Gene3D G3DSA:1.20.1250.20 220 399 2.2E-16 T 28-03-2018 SMD44_RS04070 4be8d61d722fb72847105e141afc60d2 399 Gene3D G3DSA:1.20.1250.20 20 216 1.3E-16 T 28-03-2018 SMD44_RS04070 4be8d61d722fb72847105e141afc60d2 399 Pfam PF07690 Major Facilitator Superfamily 33 230 4.2E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS04070 4be8d61d722fb72847105e141afc60d2 399 SUPERFAMILY SSF103473 20 396 8.63E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 SUPERFAMILY SSF53720 19 435 4.9E-72 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 Gene3D G3DSA:3.40.50.1980 230 377 3.2E-58 T 28-03-2018 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PIRSF PIRSF000099 4 436 1.7E-160 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 432 1.5E-140 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PRINTS PR00083 Histidinol dehydrogenase signature 367 385 7.2E-84 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 7.2E-84 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 7.2E-84 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 7.2E-84 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PRINTS PR00083 Histidinol dehydrogenase signature 326 351 7.2E-84 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 7.2E-84 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 7.2E-84 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 7.2E-84 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 Gene3D G3DSA:3.40.50.1980 29 229 1.5E-82 T 28-03-2018 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 Pfam PF00815 Histidinol dehydrogenase 24 433 1.4E-154 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS10860 6b4600c9260d5fc1c7538ec0d5f399a4 440 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 8 433 38.588 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 SUPERFAMILY SSF88659 130 187 1.55E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 Pfam PF04542 Sigma-70 region 2 14 79 3.8E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 Pfam PF12680 SnoaL-like domain 208 302 2.6E-6 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 SUPERFAMILY SSF54427 200 315 4.39E-19 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 Gene3D G3DSA:3.10.450.50 183 322 2.8E-24 T 28-03-2018 SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 187 3.9E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 Pfam PF08281 Sigma-70, region 4 132 185 3.1E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 SUPERFAMILY SSF88946 13 91 1.33E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 Gene3D G3DSA:1.10.10.10 117 182 2.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 6 318 1.0E-145 T 28-03-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria SMD44_RS26810 923ce3748e993abc0e53a712fb41e4b9 325 Gene3D G3DSA:1.10.1740.10 2 82 3.8E-24 T 28-03-2018 SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 76 155 1.9E-34 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 155 9.1E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 Gene3D G3DSA:3.30.160.70 2 70 2.4E-20 T 28-03-2018 SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 Gene3D G3DSA:1.10.10.10 71 157 1.6E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 156 42.623 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 6 72 1.2E-4 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 SUPERFAMILY SSF53155 4 80 6.08E-17 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 126 132 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS34120 25c982e8edd265c841beb98ea1f695f6 161 SUPERFAMILY SSF46767 75 156 3.66E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS06905 f9adeabda77e2af3915642369837954b 544 Pfam PF07969 Amidohydrolase family 57 539 3.1E-102 T 28-03-2018 IPR013108 Amidohydrolase 3 SMD44_RS06905 f9adeabda77e2af3915642369837954b 544 SUPERFAMILY SSF51556 68 129 4.4E-34 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS06905 f9adeabda77e2af3915642369837954b 544 SUPERFAMILY SSF51556 195 473 4.4E-34 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS06905 f9adeabda77e2af3915642369837954b 544 SUPERFAMILY SSF51338 475 512 2.14E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS06905 f9adeabda77e2af3915642369837954b 544 SUPERFAMILY SSF51338 7 69 2.14E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS06905 f9adeabda77e2af3915642369837954b 544 Gene3D G3DSA:3.20.20.140 82 475 4.6E-45 T 28-03-2018 SMD44_RS06905 f9adeabda77e2af3915642369837954b 544 Gene3D G3DSA:2.30.40.10 11 81 7.8E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 Gene3D G3DSA:3.40.50.300 16 35 0.013 T 28-03-2018 SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 SUPERFAMILY SSF52540 23 153 2.47E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 Pfam PF00149 Calcineurin-like phosphoesterase 195 384 1.7E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 SUPERFAMILY SSF56091 482 622 6.04E-12 T 28-03-2018 SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 SUPERFAMILY SSF56091 691 781 6.04E-12 T 28-03-2018 SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 Gene3D G3DSA:3.40.50.300 36 158 4.6E-15 T 28-03-2018 SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 807 866 2.1E-31 T 28-03-2018 IPR032390 Polynucleotide kinase-phosphatase, C-terminal SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 Gene3D G3DSA:3.60.21.10 185 431 2.6E-50 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 16 866 0.0 T 28-03-2018 IPR024028 Polynucleotide kinase-phosphatase, bacterial SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 Pfam PF13671 AAA domain 23 150 1.8E-23 T 28-03-2018 SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 Gene3D G3DSA:3.30.470.30 432 731 0.001 T 28-03-2018 SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 SUPERFAMILY SSF56300 187 407 1.99E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS32135 a54866b2450658779a321f5235e510e4 866 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 472 803 2.8E-141 T 28-03-2018 IPR032380 Polynucleotide kinase-phosphatase, ligase domain SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 Gene3D G3DSA:3.40.50.300 66 213 8.3E-29 T 28-03-2018 SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 Gene3D G3DSA:3.40.50.300 214 350 9.8E-35 T 28-03-2018 SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 SUPERFAMILY SSF52540 68 590 1.77E-176 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 SUPERFAMILY SSF52540 622 745 1.77E-176 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 Pfam PF00580 UvrD/REP helicase N-terminal domain 72 340 1.9E-78 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 Gene3D G3DSA:3.40.50.300 351 453 8.1E-27 T 28-03-2018 SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 Gene3D G3DSA:1.10.486.10 454 652 1.0E-46 T 28-03-2018 SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 68 842 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 SMD44_RS25960 22981feefdf72d23ac88f1930f397207 844 Pfam PF13361 UvrD-like helicase C-terminal domain 346 717 8.1E-65 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD44_RS14385 e75686a0d81a5c466440d5b1e777c32a 264 Gene3D G3DSA:3.40.50.300 1 234 2.0E-62 T 28-03-2018 SMD44_RS14385 e75686a0d81a5c466440d5b1e777c32a 264 SUPERFAMILY SSF52540 1 242 1.4E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14385 e75686a0d81a5c466440d5b1e777c32a 264 SMART SM00382 27 239 2.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14385 e75686a0d81a5c466440d5b1e777c32a 264 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS14385 e75686a0d81a5c466440d5b1e777c32a 264 Pfam PF00005 ABC transporter 19 159 1.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS34630 0c6724a3c742f2041ac51c7c54fb1430 307 SMART SM00829 10 305 6.4E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS34630 0c6724a3c742f2041ac51c7c54fb1430 307 SUPERFAMILY SSF50129 1 143 3.04E-26 T 28-03-2018 IPR011032 GroES-like SMD44_RS34630 0c6724a3c742f2041ac51c7c54fb1430 307 SUPERFAMILY SSF51735 109 272 8.57E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34630 0c6724a3c742f2041ac51c7c54fb1430 307 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 81 8.6E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS34630 0c6724a3c742f2041ac51c7c54fb1430 307 Gene3D G3DSA:3.90.180.10 202 306 1.8E-6 T 28-03-2018 SMD44_RS34630 0c6724a3c742f2041ac51c7c54fb1430 307 Pfam PF13602 Zinc-binding dehydrogenase 179 305 1.2E-16 T 28-03-2018 SMD44_RS34630 0c6724a3c742f2041ac51c7c54fb1430 307 Gene3D G3DSA:3.90.180.10 1 195 8.5E-48 T 28-03-2018 SMD44_RS05175 80abc5589a115809b29b938526409567 233 Pfam PF00782 Dual specificity phosphatase, catalytic domain 91 183 3.1E-9 T 28-03-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 SMD44_RS05175 80abc5589a115809b29b938526409567 233 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 155 165 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 SMD44_RS05175 80abc5589a115809b29b938526409567 233 Gene3D G3DSA:3.90.190.10 58 219 1.5E-28 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMD44_RS05175 80abc5589a115809b29b938526409567 233 SMART SM00195 70 207 0.0045 T 28-03-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 SMD44_RS05175 80abc5589a115809b29b938526409567 233 SUPERFAMILY SSF52799 69 185 4.9E-25 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMD44_RS25430 0c8b5ead665235d161b363ec4ad01bcb 240 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 138 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25430 0c8b5ead665235d161b363ec4ad01bcb 240 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 228 42.758 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SMD44_RS25430 0c8b5ead665235d161b363ec4ad01bcb 240 SUPERFAMILY SSF56808 6 225 9.03E-83 T 28-03-2018 IPR023674 Ribosomal protein L1-like SMD44_RS25430 0c8b5ead665235d161b363ec4ad01bcb 240 PIRSF PIRSF002155 1 226 7.2E-74 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25430 0c8b5ead665235d161b363ec4ad01bcb 240 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 226 3.8E-102 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SMD44_RS25430 0c8b5ead665235d161b363ec4ad01bcb 240 Gene3D G3DSA:3.30.190.20 144 223 1.0E-17 T 28-03-2018 SMD44_RS25430 0c8b5ead665235d161b363ec4ad01bcb 240 Gene3D G3DSA:3.40.50.790 67 143 6.7E-36 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich SMD44_RS25430 0c8b5ead665235d161b363ec4ad01bcb 240 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 8.1E-53 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 SUPERFAMILY SSF53271 688 725 4.98E-8 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 Pfam PF00271 Helicase conserved C-terminal domain 255 352 4.9E-13 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 SUPERFAMILY SSF52540 44 362 1.29E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 Pfam PF00270 DEAD/DEAH box helicase 38 204 7.4E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 Gene3D G3DSA:3.40.50.300 30 215 6.9E-28 T 28-03-2018 SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 35 369 3.0E-69 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 Gene3D G3DSA:3.40.50.300 230 498 2.0E-36 T 28-03-2018 SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 SMART SM00490 272 353 2.3E-21 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 SMART SM00487 31 225 1.7E-22 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 Gene3D G3DSA:3.40.50.2020 581 728 1.5E-13 T 28-03-2018 SMD44_RS31500 a80d8074151233ead2665e4751e085fa 728 Pfam PF16124 RecQ zinc-binding 453 495 1.1E-5 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 12 454 67.772 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 SMART SM00729 157 376 1.9E-58 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 161 181 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 Pfam PF00919 Uncharacterized protein family UPF0004 15 114 7.8E-27 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 SUPERFAMILY SSF102114 143 382 5.49E-58 T 28-03-2018 SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 14 449 1.3E-152 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 14 450 2.5E-145 T 28-03-2018 SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 Gene3D G3DSA:3.80.30.20 154 389 9.1E-53 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SMD44_RS31340 756aae3352fa6fea9dab030236e63aa6 503 Pfam PF04055 Radical SAM superfamily 161 331 1.3E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS33210 a32dbeccd633de6b987906f553770f1b 289 Gene3D G3DSA:1.10.10.60 145 231 5.7E-8 T 28-03-2018 SMD44_RS33210 a32dbeccd633de6b987906f553770f1b 289 Pfam PF12833 Helix-turn-helix domain 203 277 9.4E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS33210 a32dbeccd633de6b987906f553770f1b 289 SUPERFAMILY SSF46689 231 277 1.08E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS33210 a32dbeccd633de6b987906f553770f1b 289 Gene3D G3DSA:1.10.10.60 232 284 3.2E-9 T 28-03-2018 SMD44_RS33210 a32dbeccd633de6b987906f553770f1b 289 SMART SM00342 195 278 4.7E-11 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SUPERFAMILY SSF48371 137 339 1.79E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SUPERFAMILY SSF48371 17 78 1.79E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Pfam PF13646 HEAT repeats 433 492 1.2E-8 T 28-03-2018 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Gene3D G3DSA:1.25.10.10 110 245 4.3E-6 T 28-03-2018 IPR011989 Armadillo-like helical SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Gene3D G3DSA:1.25.40.70 344 412 2.9E-5 T 28-03-2018 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Gene3D G3DSA:1.25.40.70 266 343 9.7E-5 T 28-03-2018 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Gene3D G3DSA:1.25.40.70 68 109 0.012 T 28-03-2018 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Gene3D G3DSA:1.25.40.70 1 67 0.0013 T 28-03-2018 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Gene3D G3DSA:1.25.40.70 413 482 1.6E-8 T 28-03-2018 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Gene3D G3DSA:1.25.10.10 520 674 0.0017 T 28-03-2018 IPR011989 Armadillo-like helical SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SUPERFAMILY SSF48371 299 492 4.03E-20 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 436 465 5.1 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 159 188 81.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 610 639 210.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 370 399 0.11 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 309 338 0.011 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 31 61 78.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 528 556 550.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 467 496 79.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 63 89 62.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 SMART SM00567 E-Z type HEAT repeats 403 432 71.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Pfam PF03130 PBS lyase HEAT-like repeat 63 87 0.0078 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Pfam PF03130 PBS lyase HEAT-like repeat 373 398 0.11 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS32245 0c9e8d4433822156f51031a6bbee8723 708 Pfam PF03130 PBS lyase HEAT-like repeat 311 337 0.091 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 SUPERFAMILY SSF51989 43 340 4.32E-83 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 PIRSF PIRSF001100 20 344 1.6E-88 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 Gene3D G3DSA:3.20.20.40 42 340 1.2E-99 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 120 136 - T 28-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 Pfam PF01341 Glycosyl hydrolases family 6 52 322 2.0E-80 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 PRINTS PR00733 Glycosyl hydrolase family 6 signature 199 212 1.7E-37 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 PRINTS PR00733 Glycosyl hydrolase family 6 signature 279 299 1.7E-37 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 PRINTS PR00733 Glycosyl hydrolase family 6 signature 261 274 1.7E-37 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 PRINTS PR00733 Glycosyl hydrolase family 6 signature 303 317 1.7E-37 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 PRINTS PR00733 Glycosyl hydrolase family 6 signature 115 128 1.7E-37 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 PRINTS PR00733 Glycosyl hydrolase family 6 signature 143 158 1.7E-37 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS10430 4742fc3f1ef6780eba1316c3b9f06552 382 PRINTS PR00733 Glycosyl hydrolase family 6 signature 230 240 1.7E-37 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS22875 da7b9319e7a648efd879777958d98520 242 Gene3D G3DSA:3.40.50.880 35 240 8.0E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS22875 da7b9319e7a648efd879777958d98520 242 SUPERFAMILY SSF52317 43 234 1.48E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS22875 da7b9319e7a648efd879777958d98520 242 Pfam PF01965 DJ-1/PfpI family 45 209 4.1E-19 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 Gene3D G3DSA:1.10.10.250 75 143 5.1E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 SUPERFAMILY SSF54747 5 75 6.8E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 5.6E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.376 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 2.3E-63 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 3.6E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 SMART SM00649 12 143 2.5E-86 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 SUPERFAMILY SSF46906 70 143 4.19E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 6.0E-17 T 28-03-2018 SMD44_RS25425 1336a5edda4ebd9d6289d2ea15b5746c 144 Gene3D G3DSA:3.30.1550.10 6 74 1.4E-34 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 PRINTS PR00775 90kDa heat shock protein signature 630 652 1.8E-6 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 PRINTS PR00775 90kDa heat shock protein signature 683 700 1.8E-6 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 PRINTS PR00775 90kDa heat shock protein signature 734 756 1.8E-6 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 634 757 8.7E-6 T 28-03-2018 SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 SUPERFAMILY SSF55874 610 809 2.56E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 SUPERFAMILY SSF52129 3 213 1.48E-16 T 28-03-2018 IPR029030 Caspase-like domain SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 Gene3D G3DSA:3.40.50.1460 2 234 1.6E-30 T 28-03-2018 SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 Gene3D G3DSA:3.30.565.10 633 837 2.0E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07780 23b7a39086eae2a419abb76e7410178e 1682 Pfam PF00656 Caspase domain 6 228 1.2E-10 T 28-03-2018 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 SMART SM00388 252 315 2.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 5.5E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 5.5E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 SUPERFAMILY SSF158472 199 249 7.06E-7 T 28-03-2018 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 Gene3D G3DSA:1.10.287.130 242 295 7.8E-13 T 28-03-2018 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 Gene3D G3DSA:3.30.565.10 296 465 4.3E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 Pfam PF00672 HAMP domain 199 247 1.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 314 4.9E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 SMART SM00387 357 467 3.1E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 465 5.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 SUPERFAMILY SSF47384 235 313 2.35E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 SUPERFAMILY SSF55874 304 468 4.98E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31280 af3748c86ce5f6c351474acd629fba37 490 SMART SM00304 198 251 7.2E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS07890 b404b54e4b30923b1b092cfee51f14e4 384 Gene3D G3DSA:3.60.40.10 96 365 5.2E-22 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS07890 b404b54e4b30923b1b092cfee51f14e4 384 SMART SM00331 127 364 1.1E-22 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS07890 b404b54e4b30923b1b092cfee51f14e4 384 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 156 363 1.5E-36 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS07890 b404b54e4b30923b1b092cfee51f14e4 384 SUPERFAMILY SSF81606 145 363 4.45E-5 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 Pfam PF01580 FtsK/SpoIIIE family 990 1191 6.2E-24 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 Pfam PF01580 FtsK/SpoIIIE family 648 857 2.2E-31 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 Gene3D G3DSA:3.40.50.300 1207 1423 4.6E-6 T 28-03-2018 SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 SMART SM00382 1006 1182 0.002 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 SMART SM00382 671 848 0.0037 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 SMART SM00382 1303 1435 1.1 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 Gene3D G3DSA:2.60.200.20 110 220 6.6E-4 T 28-03-2018 SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 SUPERFAMILY SSF52540 1292 1414 2.06E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 Gene3D G3DSA:3.40.50.300 976 1197 1.0E-12 T 28-03-2018 SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 Gene3D G3DSA:3.40.50.300 302 872 2.0E-28 T 28-03-2018 SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 SUPERFAMILY SSF52540 956 1188 3.76E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS24585 d9a63305fcf6f1f49751ba405a8fdd2d 1486 SUPERFAMILY SSF52540 656 880 2.87E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20625 ee88381c48b508dee3360f4ea7f5e7a1 495 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 300 494 2.1E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS20625 ee88381c48b508dee3360f4ea7f5e7a1 495 SMART SM00331 273 494 5.7E-18 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS20625 ee88381c48b508dee3360f4ea7f5e7a1 495 Gene3D G3DSA:3.60.40.10 249 495 5.2E-29 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS20625 ee88381c48b508dee3360f4ea7f5e7a1 495 Gene3D G3DSA:3.30.450.40 53 248 4.3E-31 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS01040 7598ddf4b5581e433d2381d94b4f6462 479 PIRSF PIRSF019251 4 476 1.2E-187 T 28-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 SMD44_RS01040 7598ddf4b5581e433d2381d94b4f6462 479 SUPERFAMILY SSF47413 12 73 2.57E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS01040 7598ddf4b5581e433d2381d94b4f6462 479 Gene3D G3DSA:1.10.260.40 4 73 2.9E-17 T 28-03-2018 SMD44_RS01040 7598ddf4b5581e433d2381d94b4f6462 479 Pfam PF01381 Helix-turn-helix 15 69 1.4E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS01040 7598ddf4b5581e433d2381d94b4f6462 479 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 315 471 4.1E-70 T 28-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator SMD44_RS01040 7598ddf4b5581e433d2381d94b4f6462 479 Pfam PF06114 IrrE N-terminal-like domain 192 314 1.6E-20 T 28-03-2018 IPR010359 IrrE N-terminal-like domain SMD44_RS01040 7598ddf4b5581e433d2381d94b4f6462 479 SMART SM00530 14 69 5.0E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 Gene3D G3DSA:3.90.79.10 223 390 9.7E-22 T 28-03-2018 SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 PRINTS PR00502 NUDIX hydrolase family signature 285 300 3.3E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 PRINTS PR00502 NUDIX hydrolase family signature 271 285 3.3E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 ProSitePatterns PS00893 Nudix box signature. 276 297 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 SUPERFAMILY SSF53335 46 217 1.18E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 SUPERFAMILY SSF55811 221 361 1.35E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 Gene3D G3DSA:3.40.50.150 2 222 5.5E-23 T 28-03-2018 SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 Pfam PF13649 Methyltransferase domain 56 147 1.5E-9 T 28-03-2018 SMD44_RS42675 9231fd758a0a594b800b18db58fd90b3 401 Pfam PF00293 NUDIX domain 249 357 1.0E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS09285 ca98a0951c4f6a189ed8d26716fa92e6 263 Gene3D G3DSA:3.40.50.300 1 238 1.9E-49 T 28-03-2018 SMD44_RS09285 ca98a0951c4f6a189ed8d26716fa92e6 263 Pfam PF00005 ABC transporter 21 171 4.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS09285 ca98a0951c4f6a189ed8d26716fa92e6 263 SUPERFAMILY SSF52540 4 230 4.7E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09285 ca98a0951c4f6a189ed8d26716fa92e6 263 SMART SM00382 29 222 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 SUPERFAMILY SSF53067 11 149 2.45E-21 T 28-03-2018 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 Gene3D G3DSA:3.30.420.40 161 196 0.063 T 28-03-2018 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 Gene3D G3DSA:3.90.640.10 197 252 1.9E-14 T 28-03-2018 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 Pfam PF06723 MreB/Mbl protein 11 332 8.3E-109 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 Gene3D G3DSA:3.30.420.40 9 160 3.8E-18 T 28-03-2018 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 68 91 4.8E-36 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 4.8E-36 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 302 328 4.8E-36 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 48 66 4.8E-36 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 4.8E-36 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 Gene3D G3DSA:3.30.420.40 253 319 8.5E-8 T 28-03-2018 SMD44_RS13000 d6dd5e012deb258dd3a39000551a0387 345 SUPERFAMILY SSF53067 150 330 2.89E-33 T 28-03-2018 SMD44_RS09040 205030b7320b3b28dbddc853bc76ca7c 227 SUPERFAMILY SSF69593 32 217 2.22E-33 T 28-03-2018 SMD44_RS09040 205030b7320b3b28dbddc853bc76ca7c 227 SMART SM00563 53 163 1.5E-24 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS09040 205030b7320b3b28dbddc853bc76ca7c 227 Pfam PF01553 Acyltransferase 41 160 6.1E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS09040 205030b7320b3b28dbddc853bc76ca7c 227 Gene3D G3DSA:3.40.1130.10 39 225 1.5E-34 T 28-03-2018 SMD44_RS03555 0dc1aaae0489913379da590586ed97e6 396 SUPERFAMILY SSF47203 232 392 5.96E-27 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS03555 0dc1aaae0489913379da590586ed97e6 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 385 4.8E-32 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS03555 0dc1aaae0489913379da590586ed97e6 396 SUPERFAMILY SSF56645 3 245 7.33E-68 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS03555 0dc1aaae0489913379da590586ed97e6 396 Gene3D G3DSA:1.20.140.10 230 396 8.3E-35 T 28-03-2018 SMD44_RS03555 0dc1aaae0489913379da590586ed97e6 396 Gene3D G3DSA:1.10.540.10 1 120 1.1E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS03555 0dc1aaae0489913379da590586ed97e6 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 4.6E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS03555 0dc1aaae0489913379da590586ed97e6 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 206 1.4E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS03555 0dc1aaae0489913379da590586ed97e6 396 Gene3D G3DSA:2.40.110.10 123 229 3.1E-29 T 28-03-2018 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 Gene3D G3DSA:3.40.50.800 283 409 2.0E-32 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 Pfam PF03129 Anticodon binding domain 290 378 9.3E-15 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 471 39.851 T 28-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 3.2E-6 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 3.2E-6 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 3.2E-6 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 3.2E-6 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 SUPERFAMILY SSF52954 279 400 1.96E-27 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 SUPERFAMILY SSF55681 12 277 9.95E-73 T 28-03-2018 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 Gene3D G3DSA:3.30.930.10 7 282 1.6E-59 T 28-03-2018 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 SMART SM00946 409 471 0.0027 T 28-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 103 270 1.2E-12 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS30465 ebb66f6f469dc57bf5648da0ddbc12d3 471 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 417 5.6E-141 T 28-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMD44_RS16270 0d6e6df484588e961cc91d409369289b 390 Pfam PF06224 Winged helix DNA-binding domain 37 365 2.5E-65 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 SMD44_RS30020 638fe1f1e7c0c888cb80e07d3ce56bd5 362 Gene3D G3DSA:3.30.470.10 2 181 1.2E-71 T 28-03-2018 SMD44_RS30020 638fe1f1e7c0c888cb80e07d3ce56bd5 362 ProSitePatterns PS00770 Aminotransferases class-IV signature. 238 267 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS30020 638fe1f1e7c0c888cb80e07d3ce56bd5 362 Pfam PF01063 Amino-transferase class IV 74 316 1.3E-32 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS30020 638fe1f1e7c0c888cb80e07d3ce56bd5 362 SUPERFAMILY SSF56752 12 359 3.01E-115 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS30020 638fe1f1e7c0c888cb80e07d3ce56bd5 362 Gene3D G3DSA:3.20.10.10 182 357 1.1E-48 T 28-03-2018 SMD44_RS30020 638fe1f1e7c0c888cb80e07d3ce56bd5 362 PIRSF PIRSF006468 5 362 3.4E-131 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 SMD44_RS30020 638fe1f1e7c0c888cb80e07d3ce56bd5 362 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 360 2.2E-133 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 SMD44_RS08790 d893251115504af80f333b98ea371df1 228 Gene3D G3DSA:1.10.10.10 162 228 7.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08790 d893251115504af80f333b98ea371df1 228 Gene3D G3DSA:3.40.50.2300 1 144 6.6E-33 T 28-03-2018 SMD44_RS08790 d893251115504af80f333b98ea371df1 228 SUPERFAMILY SSF52172 1 138 2.85E-36 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS08790 d893251115504af80f333b98ea371df1 228 PIRSF PIRSF006171 1 228 4.7E-74 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMD44_RS08790 d893251115504af80f333b98ea371df1 228 Pfam PF00072 Response regulator receiver domain 4 121 2.8E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS08790 d893251115504af80f333b98ea371df1 228 SMART SM00448 2 121 5.4E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2003 2119 1.1E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3713 3829 1.1E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 411 6.3E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3618 3634 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF52151 2454 2565 2.43E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF52151 2277 2394 2.43E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.366.10 740 865 1.4E-29 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF51735 1200 1359 1.06E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1908 1924 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF53901 3452 3829 1.15E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF51735 2910 3070 5.12E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF53901 33 155 2.44E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF53901 182 408 2.44E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF47336 3359 3470 2.75E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF53901 1738 1863 1.47E-105 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF53901 1891 2117 1.47E-105 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3391 3406 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00826 923 1086 6.0E-83 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00826 2634 2798 1.9E-83 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.50.720 3082 3333 1.8E-47 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.50.720 1370 1616 4.9E-48 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.366.10 2448 2562 1.6E-34 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3832 3888 4.5E-7 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 532 4.1E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2122 2243 8.4E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00825 Beta-ketoacyl synthase 36 464 1.7E-223 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00825 Beta-ketoacyl synthase 3457 3882 1.5E-222 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00825 Beta-ketoacyl synthase 1744 2172 2.7E-221 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF00698 Acyl transferase domain 2279 2586 1.1E-57 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF00698 Acyl transferase domain 568 875 3.4E-59 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF51735 1371 1580 2.27E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00823 Phosphopantetheine attachment site 3364 3436 1.7E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00823 Phosphopantetheine attachment site 1652 1724 5.1E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 286 7.9E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3455 3705 1.0E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1742 1995 2.2E-94 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.47.10 3453 3717 3.1E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.47.10 1734 2007 1.1E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.47.10 26 298 2.3E-90 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:1.10.1200.10 1619 1731 1.1E-18 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3083 3259 9.5E-59 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1371 1547 4.3E-60 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF55048 2399 2461 1.28E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.10.129.10 2640 2756 8.6E-8 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.10.129.10 928 1052 5.2E-7 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF52151 566 683 7.32E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF52151 743 855 7.32E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF14765 Polyketide synthase dehydratase 2634 2906 3.8E-56 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF14765 Polyketide synthase dehydratase 923 1192 2.6E-55 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.30.70.250 699 739 1.4E-17 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF51735 3083 3284 4.85E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF55048 688 750 5.23E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF08659 KR domain 1371 1546 9.3E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF08659 KR domain 3083 3258 3.1E-57 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM01294 3373 3432 8.3E-4 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM01294 1652 1720 1.7E-4 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:1.10.1200.10 3357 3452 1.4E-18 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.366.10 2276 2404 2.3E-43 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.366.10 565 698 1.7E-41 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1679 1694 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF08990 Erythronolide synthase docking 2 27 5.5E-9 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF00550 Phosphopantetheine attachment site 1655 1720 4.9E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Pfam PF00550 Phosphopantetheine attachment site 3367 3432 3.4E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.30.70.250 2405 2447 6.4E-16 T 28-03-2018 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.47.10 3720 3880 2.1E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.47.10 301 462 2.9E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 Gene3D G3DSA:3.40.47.10 2010 2170 1.8E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2280 2567 5.4E-117 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 569 856 1.5E-113 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02285 9a57106e99d0147ca13f5c5acd64f9c5 3933 SUPERFAMILY SSF47336 1648 1757 8.64E-25 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36120 76bc7b8e0d5ebe6946be8aade088aa96 74 SUPERFAMILY SSF160582 3 71 7.45E-33 T 28-03-2018 SMD44_RS36120 76bc7b8e0d5ebe6946be8aade088aa96 74 SMART SM00923 4 54 2.3E-34 T 28-03-2018 IPR005153 MbtH-like protein SMD44_RS36120 76bc7b8e0d5ebe6946be8aade088aa96 74 Pfam PF03621 MbtH-like protein 2 54 3.0E-30 T 28-03-2018 IPR005153 MbtH-like protein SMD44_RS36120 76bc7b8e0d5ebe6946be8aade088aa96 74 Gene3D G3DSA:3.90.820.10 3 69 2.2E-37 T 28-03-2018 SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 145 166 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 SUPERFAMILY SSF51735 121 264 1.23E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 SMART SM00829 10 325 1.9E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 Gene3D G3DSA:3.90.180.10 1 154 7.6E-37 T 28-03-2018 SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 Pfam PF00107 Zinc-binding dehydrogenase 156 273 5.4E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 92 2.3E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 SUPERFAMILY SSF50129 1 154 4.56E-28 T 28-03-2018 IPR011032 GroES-like SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 Gene3D G3DSA:3.90.180.10 262 329 0.0021 T 28-03-2018 SMD44_RS08650 e0d9cd0f60e81b8fed66fb6aee73c6dd 336 Gene3D G3DSA:3.40.50.720 155 261 6.0E-20 T 28-03-2018 SMD44_RS23600 8c4a8a15353bc5bbf0b42f1be5d10037 82 Pfam PF01197 Ribosomal protein L31 2 79 5.5E-28 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23600 8c4a8a15353bc5bbf0b42f1be5d10037 82 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23600 8c4a8a15353bc5bbf0b42f1be5d10037 82 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.457 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23600 8c4a8a15353bc5bbf0b42f1be5d10037 82 SUPERFAMILY SSF143800 2 79 1.41E-20 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23600 8c4a8a15353bc5bbf0b42f1be5d10037 82 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.2E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23600 8c4a8a15353bc5bbf0b42f1be5d10037 82 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.2E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23600 8c4a8a15353bc5bbf0b42f1be5d10037 82 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.2E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23600 8c4a8a15353bc5bbf0b42f1be5d10037 82 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 1.1E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SMART SM00028 932 965 190.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SMART SM00028 772 805 0.87 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SMART SM00028 77 110 460.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SMART SM00028 892 925 0.17 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SMART SM00028 852 885 0.42 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 PRINTS PR00364 Disease resistance protein signature 461 475 2.1E-9 T 28-03-2018 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 PRINTS PR00364 Disease resistance protein signature 299 314 2.1E-9 T 28-03-2018 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 PRINTS PR00364 Disease resistance protein signature 376 390 2.1E-9 T 28-03-2018 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Pfam PF03704 Bacterial transcriptional activator domain 72 216 2.1E-39 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Gene3D G3DSA:3.30.70.100 724 818 1.5E-8 T 28-03-2018 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SUPERFAMILY SSF48452 67 228 4.17E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SUPERFAMILY SSF48452 755 964 9.49E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Pfam PF13424 Tetratricopeptide repeat 773 840 2.6E-8 T 28-03-2018 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Gene3D G3DSA:1.10.10.10 1 73 5.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Gene3D G3DSA:3.40.50.300 259 416 2.1E-18 T 28-03-2018 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Pfam PF00486 Transcriptional regulatory protein, C terminal 2 65 1.6E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SUPERFAMILY SSF52540 260 526 2.42E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Gene3D G3DSA:1.25.40.10 74 258 1.8E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SUPERFAMILY SSF46894 1 65 3.97E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Gene3D G3DSA:1.25.40.10 819 985 4.2E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 SMART SM01043 72 216 1.1E-47 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Pfam PF13374 Tetratricopeptide repeat 852 885 0.0049 T 28-03-2018 SMD44_RS23050 564347d08fbaf91a28e2d289659f1c06 989 Pfam PF00931 NB-ARC domain 279 531 2.8E-15 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Pfam PF08659 KR domain 956 1135 3.6E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Gene3D G3DSA:3.40.366.10 88 207 1.6E-23 T 28-03-2018 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Pfam PF00698 Acyl transferase domain 1 220 7.7E-40 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SUPERFAMILY SSF52151 92 186 2.88E-26 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SUPERFAMILY SSF52151 1 28 2.88E-26 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Pfam PF14765 Polyketide synthase dehydratase 268 551 5.5E-56 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SUPERFAMILY SSF51735 773 896 1.08E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Pfam PF00550 Phosphopantetheine attachment site 1238 1303 1.0E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SUPERFAMILY SSF47336 1226 1313 7.72E-25 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Gene3D G3DSA:1.10.1200.10 1228 1308 3.4E-23 T 28-03-2018 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SUPERFAMILY SSF55048 26 91 1.83E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Gene3D G3DSA:3.30.70.250 27 87 2.5E-15 T 28-03-2018 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SMART SM01294 1236 1303 1.3E-5 T 28-03-2018 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SMART SM00823 Phosphopantetheine attachment site 1235 1307 9.0E-36 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Gene3D G3DSA:3.10.129.10 269 400 1.5E-7 T 28-03-2018 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 201 3.8E-29 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SUPERFAMILY SSF51735 950 1203 2.48E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SMART SM00826 268 435 3.4E-76 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 Gene3D G3DSA:3.40.50.720 948 1227 9.0E-44 T 28-03-2018 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 956 1136 1.6E-61 T 28-03-2018 SMD44_RS36505 e07effb4fbe72f7197f3d0052a9d8117 1427 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1262 1277 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS39635 d2e7633449dd5fb473e0f2c982a33990 628 Pfam PF00664 ABC transporter transmembrane region 52 316 2.6E-33 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS39635 d2e7633449dd5fb473e0f2c982a33990 628 Pfam PF00005 ABC transporter 388 535 3.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS39635 d2e7633449dd5fb473e0f2c982a33990 628 Gene3D G3DSA:3.40.50.300 356 608 1.1E-73 T 28-03-2018 SMD44_RS39635 d2e7633449dd5fb473e0f2c982a33990 628 SMART SM00382 395 581 1.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS39635 d2e7633449dd5fb473e0f2c982a33990 628 SUPERFAMILY SSF90123 38 355 7.85E-60 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS39635 d2e7633449dd5fb473e0f2c982a33990 628 Gene3D G3DSA:1.20.1560.10 11 352 1.2E-51 T 28-03-2018 SMD44_RS39635 d2e7633449dd5fb473e0f2c982a33990 628 ProSitePatterns PS00211 ABC transporters family signature. 507 521 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS39635 d2e7633449dd5fb473e0f2c982a33990 628 SUPERFAMILY SSF52540 364 606 5.33E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00315 bb57ae13e36a1e0dd60bbbfb9ce7e1ed 241 SUPERFAMILY SSF51197 9 239 2.79E-33 T 28-03-2018 SMD44_RS00315 bb57ae13e36a1e0dd60bbbfb9ce7e1ed 241 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 10 237 4.0E-24 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD44_RS00315 bb57ae13e36a1e0dd60bbbfb9ce7e1ed 241 Gene3D G3DSA:3.60.130.10 6 241 4.4E-33 T 28-03-2018 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 SMART SM00870 4 313 4.9E-90 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 Pfam PF00710 Asparaginase, N-terminal 5 178 1.2E-42 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 PIRSF PIRSF001220 2 320 5.5E-70 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 Gene3D G3DSA:3.40.50.40 200 322 2.8E-22 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 Gene3D G3DSA:3.40.50.1170 2 195 1.5E-40 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 PRINTS PR00139 Asparaginase/glutaminase family signature 247 265 3.3E-10 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 PRINTS PR00139 Asparaginase/glutaminase family signature 74 92 3.3E-10 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 PRINTS PR00139 Asparaginase/glutaminase family signature 5 16 3.3E-10 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 PIRSF PIRSF500176 2 321 1.5E-67 T 28-03-2018 SMD44_RS11740 1e857336bfedb7aa0218c3e2069eb5de 322 SUPERFAMILY SSF53774 3 318 4.45E-71 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMD44_RS14490 396f4439943fefd89f5717f099698249 352 Gene3D G3DSA:3.40.190.10 98 215 1.5E-26 T 28-03-2018 SMD44_RS14490 396f4439943fefd89f5717f099698249 352 SUPERFAMILY SSF53850 98 338 6.21E-51 T 28-03-2018 SMD44_RS14490 396f4439943fefd89f5717f099698249 352 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 111 335 5.0E-50 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS14490 396f4439943fefd89f5717f099698249 352 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 136 149 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SMD44_RS14490 396f4439943fefd89f5717f099698249 352 SMART SM00062 110 338 5.4E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS14490 396f4439943fefd89f5717f099698249 352 Gene3D G3DSA:3.40.190.10 216 299 1.2E-18 T 28-03-2018 SMD44_RS07140 d64297a0f3f9176977e599442918347b 349 Gene3D G3DSA:3.40.50.150 100 343 3.3E-38 T 28-03-2018 SMD44_RS07140 d64297a0f3f9176977e599442918347b 349 Gene3D G3DSA:1.10.10.10 8 99 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07140 d64297a0f3f9176977e599442918347b 349 Pfam PF00891 O-methyltransferase 110 324 1.4E-45 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD44_RS07140 d64297a0f3f9176977e599442918347b 349 SUPERFAMILY SSF53335 97 330 6.27E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS07140 d64297a0f3f9176977e599442918347b 349 SUPERFAMILY SSF46785 18 95 5.13E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07140 d64297a0f3f9176977e599442918347b 349 PIRSF PIRSF005739 1 336 3.9E-46 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD44_RS15585 9889ffc9ade593c3b936f874c64a7d4c 118 Gene3D G3DSA:2.30.33.40 11 104 8.7E-21 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS15585 9889ffc9ade593c3b936f874c64a7d4c 118 SMART SM00883 16 103 2.8E-26 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS15585 9889ffc9ade593c3b936f874c64a7d4c 118 PRINTS PR00297 10kDa chaperonin signature 17 32 6.4E-9 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS15585 9889ffc9ade593c3b936f874c64a7d4c 118 PRINTS PR00297 10kDa chaperonin signature 90 103 6.4E-9 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS15585 9889ffc9ade593c3b936f874c64a7d4c 118 PRINTS PR00297 10kDa chaperonin signature 69 81 6.4E-9 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS15585 9889ffc9ade593c3b936f874c64a7d4c 118 PRINTS PR00297 10kDa chaperonin signature 43 64 6.4E-9 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS15585 9889ffc9ade593c3b936f874c64a7d4c 118 Pfam PF00166 Chaperonin 10 Kd subunit 16 102 3.0E-19 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS15585 9889ffc9ade593c3b936f874c64a7d4c 118 SUPERFAMILY SSF50129 16 103 9.28E-18 T 28-03-2018 IPR011032 GroES-like SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 Pfam PF00107 Zinc-binding dehydrogenase 190 319 1.0E-28 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 SUPERFAMILY SSF50129 4 186 2.13E-55 T 28-03-2018 IPR011032 GroES-like SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 SUPERFAMILY SSF51735 154 326 7.39E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 Gene3D G3DSA:3.90.180.10 6 173 9.1E-47 T 28-03-2018 SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 3.9E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 Gene3D G3DSA:3.40.50.10730 174 296 1.9E-35 T 28-03-2018 SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 5.3E-212 T 28-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 SUPERFAMILY SSF50129 310 361 2.83E-9 T 28-03-2018 IPR011032 GroES-like SMD44_RS03000 cb85a615a2de7839fd5ef022cf7e25d3 361 SMART SM00829 14 359 2.2E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS30750 df9bd794e02f26d902e15973fadae735 296 Gene3D G3DSA:1.20.144.10 99 290 2.3E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS30750 df9bd794e02f26d902e15973fadae735 296 SMART SM00014 169 277 0.0011 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS30750 df9bd794e02f26d902e15973fadae735 296 SUPERFAMILY SSF48317 77 282 9.94E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS30750 df9bd794e02f26d902e15973fadae735 296 Pfam PF01569 PAP2 superfamily 198 278 1.6E-11 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 114 137 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 SUPERFAMILY SSF53623 111 337 1.57E-45 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 SUPERFAMILY SSF53244 341 484 1.25E-40 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 Gene3D G3DSA:3.90.190.20 344 483 2.6E-39 T 28-03-2018 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 177 482 4.8E-77 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 Pfam PF02875 Mur ligase family, glutamate ligase domain 342 409 2.3E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 Pfam PF08245 Mur ligase middle domain 116 320 1.7E-24 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 484 34.524 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 SUPERFAMILY SSF51984 3 97 3.53E-16 T 28-03-2018 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 Gene3D G3DSA:3.40.1190.10 98 343 9.7E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11040 41c011a52ec069ff701a6e1adb8fe566 488 Gene3D G3DSA:3.40.50.720 2 97 1.2E-21 T 28-03-2018 SMD44_RS17810 ecc62cec2e027591f0a521358e983b7a 503 SUPERFAMILY SSF103473 5 192 5.75E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17810 ecc62cec2e027591f0a521358e983b7a 503 SUPERFAMILY SSF103473 246 465 5.75E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17810 ecc62cec2e027591f0a521358e983b7a 503 Pfam PF07690 Major Facilitator Superfamily 14 408 6.3E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS17810 ecc62cec2e027591f0a521358e983b7a 503 Gene3D G3DSA:1.20.1250.20 250 468 5.8E-29 T 28-03-2018 SMD44_RS17810 ecc62cec2e027591f0a521358e983b7a 503 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS17810 ecc62cec2e027591f0a521358e983b7a 503 Gene3D G3DSA:1.20.1250.20 4 197 7.1E-32 T 28-03-2018 SMD44_RS27125 0c1dfcda8efc9bab286d576bd8b2705b 283 PIRSF PIRSF006648 2 283 3.5E-72 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS27125 0c1dfcda8efc9bab286d576bd8b2705b 283 Pfam PF01061 ABC-2 type transporter 26 236 1.7E-27 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 Gene3D G3DSA:1.10.405.10 119 196 4.2E-11 T 28-03-2018 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 Gene3D G3DSA:3.90.660.10 33 118 1.9E-15 T 28-03-2018 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 PRINTS PR00757 Flavin-containing amine oxidase signature 418 435 7.9E-28 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 PRINTS PR00757 Flavin-containing amine oxidase signature 11 30 7.9E-28 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 PRINTS PR00757 Flavin-containing amine oxidase signature 366 385 7.9E-28 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 PRINTS PR00757 Flavin-containing amine oxidase signature 286 305 7.9E-28 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 PRINTS PR00757 Flavin-containing amine oxidase signature 387 409 7.9E-28 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 SUPERFAMILY SSF54373 282 386 2.16E-25 T 28-03-2018 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 Gene3D G3DSA:3.90.660.10 222 385 2.4E-29 T 28-03-2018 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 SUPERFAMILY SSF51905 9 301 1.42E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 SUPERFAMILY SSF51905 398 438 1.42E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00745 46022940e025cdda69bf2d68d5c26451 451 Pfam PF01593 Flavin containing amine oxidoreductase 20 437 8.2E-58 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS08480 85d4baf59d68831d48296159ce213aae 551 Gene3D G3DSA:3.50.50.60 2 551 5.1E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08480 85d4baf59d68831d48296159ce213aae 551 Pfam PF00890 FAD binding domain 6 532 1.2E-107 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS08480 85d4baf59d68831d48296159ce213aae 551 PIRSF PIRSF036654 1 550 4.1E-289 T 28-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 SMD44_RS08480 85d4baf59d68831d48296159ce213aae 551 SUPERFAMILY SSF51905 3 279 1.62E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08480 85d4baf59d68831d48296159ce213aae 551 SUPERFAMILY SSF51905 487 547 1.62E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS22675 f26a16b32a63e570fb5a3e15c93d5a6f 523 Gene3D G3DSA:3.40.190.10 326 460 7.3E-22 T 28-03-2018 SMD44_RS22675 f26a16b32a63e570fb5a3e15c93d5a6f 523 Pfam PF12849 PBP superfamily domain 230 469 7.8E-24 T 28-03-2018 IPR024370 PBP domain SMD44_RS22675 f26a16b32a63e570fb5a3e15c93d5a6f 523 Gene3D G3DSA:3.40.190.10 200 325 1.6E-4 T 28-03-2018 SMD44_RS22675 f26a16b32a63e570fb5a3e15c93d5a6f 523 SUPERFAMILY SSF53850 233 500 4.75E-47 T 28-03-2018 SMD44_RS32650 83ab448c5ee755aeaeb01649f568cb4c 375 Pfam PF01321 Creatinase/Prolidase N-terminal domain 17 149 1.5E-13 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 SMD44_RS32650 83ab448c5ee755aeaeb01649f568cb4c 375 SUPERFAMILY SSF55920 148 374 4.45E-72 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS32650 83ab448c5ee755aeaeb01649f568cb4c 375 Pfam PF00557 Metallopeptidase family M24 158 358 1.9E-55 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS32650 83ab448c5ee755aeaeb01649f568cb4c 375 Gene3D G3DSA:3.90.230.10 136 375 1.1E-70 T 28-03-2018 SMD44_RS32650 83ab448c5ee755aeaeb01649f568cb4c 375 Gene3D G3DSA:3.40.350.10 1 135 1.9E-19 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMD44_RS32650 83ab448c5ee755aeaeb01649f568cb4c 375 SUPERFAMILY SSF53092 6 147 5.93E-17 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 290 486 2.0E-43 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 399 413 3.4E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 384 398 3.4E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 158 177 3.4E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 464 477 3.4E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 327 349 3.4E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 Gene3D G3DSA:3.40.710.10 117 510 6.1E-42 T 28-03-2018 SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 SUPERFAMILY SSF56601 131 505 5.17E-64 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 288 503 3.2E-56 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS23680 fc3f89dce61c9b97bdcf2e8c6f716f43 510 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 126 279 1.7E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS42410 8ddfcdd36088defe04b7106727c9d4f8 225 Gene3D G3DSA:3.40.630.30 2 163 1.5E-24 T 28-03-2018 SMD44_RS42410 8ddfcdd36088defe04b7106727c9d4f8 225 Pfam PF00583 Acetyltransferase (GNAT) family 55 155 3.6E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS42410 8ddfcdd36088defe04b7106727c9d4f8 225 SUPERFAMILY SSF55729 8 191 9.49E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS40095 adee859c60077518aad3e5384ea73d38 418 Gene3D G3DSA:3.30.420.40 203 388 2.2E-44 T 28-03-2018 SMD44_RS40095 adee859c60077518aad3e5384ea73d38 418 Gene3D G3DSA:1.10.10.10 12 66 1.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40095 adee859c60077518aad3e5384ea73d38 418 Gene3D G3DSA:3.30.420.40 67 202 3.9E-29 T 28-03-2018 SMD44_RS40095 adee859c60077518aad3e5384ea73d38 418 SUPERFAMILY SSF46785 14 71 4.52E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40095 adee859c60077518aad3e5384ea73d38 418 Pfam PF00480 ROK family 82 374 1.0E-54 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS40095 adee859c60077518aad3e5384ea73d38 418 SUPERFAMILY SSF53067 79 378 7.25E-55 T 28-03-2018 SMD44_RS36890 5e70bb89374ab9af3ea28ef4432cda74 598 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 247 9.0E-82 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36890 5e70bb89374ab9af3ea28ef4432cda74 598 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36890 5e70bb89374ab9af3ea28ef4432cda74 598 SUPERFAMILY SSF53901 1 369 1.52E-92 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36890 5e70bb89374ab9af3ea28ef4432cda74 598 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 371 5.8E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36890 5e70bb89374ab9af3ea28ef4432cda74 598 Gene3D G3DSA:3.40.47.10 1 260 1.4E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36890 5e70bb89374ab9af3ea28ef4432cda74 598 SMART SM00825 Beta-ketoacyl synthase 1 427 3.4E-197 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36890 5e70bb89374ab9af3ea28ef4432cda74 598 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 375 433 3.5E-10 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36890 5e70bb89374ab9af3ea28ef4432cda74 598 Gene3D G3DSA:3.40.47.10 262 425 9.0E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12995 b91bb12baaa34efed4f2248b46655612 562 Gene3D G3DSA:1.20.1250.20 137 343 2.9E-20 T 28-03-2018 SMD44_RS12995 b91bb12baaa34efed4f2248b46655612 562 Gene3D G3DSA:1.20.1250.20 359 561 4.6E-14 T 28-03-2018 SMD44_RS12995 b91bb12baaa34efed4f2248b46655612 562 SUPERFAMILY SSF103473 151 552 5.1E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12995 b91bb12baaa34efed4f2248b46655612 562 Pfam PF05977 Transmembrane secretion effector 361 545 7.9E-13 T 28-03-2018 IPR010290 Transmembrane secretion effector SMD44_RS12995 b91bb12baaa34efed4f2248b46655612 562 Pfam PF05977 Transmembrane secretion effector 141 329 1.7E-30 T 28-03-2018 IPR010290 Transmembrane secretion effector SMD44_RS32060 99c68faad959d40acb357f1907de54ed 156 SUPERFAMILY SSF110087 14 155 1.14E-30 T 28-03-2018 IPR007410 Copper chaperone PCuAC SMD44_RS32060 99c68faad959d40acb357f1907de54ed 156 Pfam PF04314 Copper chaperone PCu(A)C 48 147 2.3E-22 T 28-03-2018 IPR007410 Copper chaperone PCuAC SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 SUPERFAMILY SSF55874 673 831 3.8E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Gene3D G3DSA:3.40.50.620 208 356 1.1E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Pfam PF00512 His Kinase A (phospho-acceptor) domain 616 683 7.2E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 760 774 4.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 778 788 4.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 793 811 4.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 817 830 4.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 SUPERFAMILY SSF47384 605 683 2.75E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 2.4E-99 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Pfam PF13493 Domain of unknown function (DUF4118) 383 488 5.5E-25 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Gene3D G3DSA:3.30.565.10 693 834 6.5E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 724 831 7.3E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Gene3D G3DSA:3.30.450.40 479 570 0.036 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Gene3D G3DSA:3.30.450.40 571 606 0.026 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Gene3D G3DSA:1.10.287.130 607 679 7.5E-16 T 28-03-2018 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Gene3D G3DSA:3.40.50.300 2 128 5.1E-23 T 28-03-2018 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Pfam PF00582 Universal stress protein family 232 346 2.3E-5 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 SUPERFAMILY SSF52402 231 348 1.56E-8 T 28-03-2018 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 SMART SM00387 723 833 2.4E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 Gene3D G3DSA:1.20.120.620 382 478 2.3E-27 T 28-03-2018 SMD44_RS31890 b9b4800372d988f8964e5ed83f3d9bdc 848 SMART SM00388 615 683 3.6E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS14980 e4ae3d0eb0445ae33e58e588664de65d 427 Gene3D G3DSA:3.50.50.60 202 410 1.6E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS14980 e4ae3d0eb0445ae33e58e588664de65d 427 SUPERFAMILY SSF51905 12 257 1.36E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS14980 e4ae3d0eb0445ae33e58e588664de65d 427 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 13 341 4.3E-123 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD44_RS14980 e4ae3d0eb0445ae33e58e588664de65d 427 Gene3D G3DSA:3.50.50.60 8 201 7.4E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS23060 2d12b55dde0e783c63c0ff06f8934bf2 263 PIRSF PIRSF036625 1 238 8.4E-61 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS23060 2d12b55dde0e783c63c0ff06f8934bf2 263 Pfam PF03861 ANTAR domain 175 226 2.1E-16 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS23060 2d12b55dde0e783c63c0ff06f8934bf2 263 Pfam PF13185 GAF domain 23 159 1.3E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS23060 2d12b55dde0e783c63c0ff06f8934bf2 263 Gene3D G3DSA:3.30.450.40 2 178 2.3E-21 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS23060 2d12b55dde0e783c63c0ff06f8934bf2 263 SUPERFAMILY SSF52172 173 227 1.64E-6 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS23060 2d12b55dde0e783c63c0ff06f8934bf2 263 Gene3D G3DSA:1.10.10.10 179 228 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23060 2d12b55dde0e783c63c0ff06f8934bf2 263 SUPERFAMILY SSF55781 22 168 7.2E-18 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS23060 2d12b55dde0e783c63c0ff06f8934bf2 263 SMART SM01012 172 227 2.0E-18 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Gene3D G3DSA:3.10.20.30 1 73 4.5E-19 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 322 873 8.1E-146 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Gene3D G3DSA:3.30.365.10 791 936 2.8E-40 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Gene3D G3DSA:3.30.365.10 630 790 1.9E-32 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 SUPERFAMILY SSF54665 159 309 2.09E-41 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 58 3.0E-5 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Gene3D G3DSA:3.30.365.10 330 454 2.0E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Gene3D G3DSA:3.90.1170.50 160 290 3.9E-38 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 178 289 5.3E-28 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 SUPERFAMILY SSF47741 84 157 1.83E-24 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Pfam PF01799 [2Fe-2S] binding domain 72 149 4.3E-25 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Gene3D G3DSA:1.10.150.120 74 159 2.6E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 SUPERFAMILY SSF56003 293 933 2.09E-169 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 SMART SM01008 178 290 1.0E-48 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 Gene3D G3DSA:3.30.365.10 455 616 1.4E-45 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS31985 50a716b527fe231d9a61cd25582685c6 941 SUPERFAMILY SSF54292 2 77 1.09E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS21500 11690c5c1f9b22e687d0395844fe3e5c 281 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 42 275 9.2E-20 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD44_RS21500 11690c5c1f9b22e687d0395844fe3e5c 281 SUPERFAMILY SSF51197 30 277 3.98E-37 T 28-03-2018 SMD44_RS21500 11690c5c1f9b22e687d0395844fe3e5c 281 Gene3D G3DSA:3.60.130.10 8 281 1.0E-37 T 28-03-2018 SMD44_RS22690 ca838545f2602641564a2e633beb174d 150 Gene3D G3DSA:3.40.50.450 1 150 2.2E-17 T 28-03-2018 SMD44_RS22690 ca838545f2602641564a2e633beb174d 150 SUPERFAMILY SSF102405 1 148 4.58E-6 T 28-03-2018 SMD44_RS01430 128e5f2fd816bc03ecfc993578c0d21a 630 Pfam PF01833 IPT/TIG domain 542 628 1.9E-5 T 28-03-2018 IPR002909 IPT domain SMD44_RS01430 128e5f2fd816bc03ecfc993578c0d21a 630 Gene3D G3DSA:3.40.390.10 178 414 4.4E-10 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD44_RS01430 128e5f2fd816bc03ecfc993578c0d21a 630 Gene3D G3DSA:2.60.40.10 540 623 9.8E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS01430 128e5f2fd816bc03ecfc993578c0d21a 630 SUPERFAMILY SSF55486 387 410 5.31E-9 T 28-03-2018 SMD44_RS01430 128e5f2fd816bc03ecfc993578c0d21a 630 SUPERFAMILY SSF55486 268 351 5.31E-9 T 28-03-2018 SMD44_RS01430 128e5f2fd816bc03ecfc993578c0d21a 630 SUPERFAMILY SSF81296 542 629 3.18E-8 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS01430 128e5f2fd816bc03ecfc993578c0d21a 630 Pfam PF13583 Metallo-peptidase family M12B Reprolysin-like 183 352 2.4E-11 T 28-03-2018 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 276 512 9.0E-113 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 Gene3D G3DSA:1.10.10.10 350 400 2.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 SUPERFAMILY SSF88946 212 350 6.15E-54 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 Pfam PF04545 Sigma-70, region 4 448 501 3.3E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 PRINTS PR00046 Major sigma-70 factor signature 452 464 6.8E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 PRINTS PR00046 Major sigma-70 factor signature 473 488 6.8E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 PRINTS PR00046 Major sigma-70 factor signature 304 317 6.8E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 PRINTS PR00046 Major sigma-70 factor signature 328 336 6.8E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 PRINTS PR00046 Major sigma-70 factor signature 488 499 6.8E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 Gene3D G3DSA:1.10.601.10 164 349 5.7E-79 T 28-03-2018 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 473 499 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 SUPERFAMILY SSF88659 353 426 3.92E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 SUPERFAMILY SSF88659 411 512 2.62E-27 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 Pfam PF04542 Sigma-70 region 2 280 349 2.9E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 304 317 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 Gene3D G3DSA:1.10.10.10 442 513 9.8E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 111 513 31.705 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 Pfam PF04539 Sigma-70 region 3 359 435 1.1E-28 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 276 501 2.0E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31530 b21497166c530f3a80dba0eb83737e11 513 Pfam PF00140 Sigma-70 factor, region 1.2 215 248 8.0E-17 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS27545 ff60ebbef4ce426b58d2115671e8e47f 464 PIRSF PIRSF006060 12 459 8.7E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS27545 ff60ebbef4ce426b58d2115671e8e47f 464 Pfam PF00324 Amino acid permease 52 400 1.2E-29 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 SUPERFAMILY SSF55620 151 305 6.12E-52 T 28-03-2018 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 194 304 2.0E-44 T 28-03-2018 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 Pfam PF01014 Uricase 17 149 3.9E-19 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 Pfam PF01014 Uricase 159 299 6.1E-28 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 Gene3D G3DSA:3.10.270.10 2 310 3.5E-112 T 28-03-2018 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 SUPERFAMILY SSF55620 11 147 1.22E-40 T 28-03-2018 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 PIRSF PIRSF000241 1 311 1.7E-103 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 PRINTS PR00093 Uricase signature 58 72 8.2E-16 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 PRINTS PR00093 Uricase signature 164 180 8.2E-16 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 PRINTS PR00093 Uricase signature 19 30 8.2E-16 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 PRINTS PR00093 Uricase signature 94 107 8.2E-16 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 PRINTS PR00093 Uricase signature 180 192 8.2E-16 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS33360 415290b62aa61b1a9c78f179bc69ca99 318 TIGRFAM TIGR03383 urate_oxi: urate oxidase 13 304 3.7E-103 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD44_RS25685 ec5f37ff70eb1dc22f8ed281ce1a915a 334 SUPERFAMILY SSF52540 20 332 1.48E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25685 ec5f37ff70eb1dc22f8ed281ce1a915a 334 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 107 251 1.7E-10 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 SMD44_RS25685 ec5f37ff70eb1dc22f8ed281ce1a915a 334 PIRSF PIRSF000545 13 334 1.6E-141 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD44_RS25685 ec5f37ff70eb1dc22f8ed281ce1a915a 334 Hamap MF_00215 Pantothenate kinase [coaA]. 1 334 171.365 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD44_RS25685 ec5f37ff70eb1dc22f8ed281ce1a915a 334 Gene3D G3DSA:3.40.50.300 21 333 1.6E-57 T 28-03-2018 SMD44_RS25685 ec5f37ff70eb1dc22f8ed281ce1a915a 334 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 22 333 2.2E-122 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD44_RS08015 cba08e9917ab8de2d3fc9852c38a0cc7 191 SUPERFAMILY SSF51182 53 177 1.08E-17 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS08015 cba08e9917ab8de2d3fc9852c38a0cc7 191 Pfam PF13560 Helix-turn-helix domain 10 69 3.6E-11 T 28-03-2018 SMD44_RS08015 cba08e9917ab8de2d3fc9852c38a0cc7 191 Gene3D G3DSA:2.60.120.10 74 187 1.2E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS08015 cba08e9917ab8de2d3fc9852c38a0cc7 191 Pfam PF07883 Cupin domain 118 177 1.2E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS08015 cba08e9917ab8de2d3fc9852c38a0cc7 191 SMART SM00530 13 68 4.4E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS08015 cba08e9917ab8de2d3fc9852c38a0cc7 191 Gene3D G3DSA:1.10.260.40 6 73 1.3E-14 T 28-03-2018 SMD44_RS08015 cba08e9917ab8de2d3fc9852c38a0cc7 191 SUPERFAMILY SSF47413 6 73 1.01E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS28130 a6b9e51ec63b649afd0f622b39dfbb12 378 SUPERFAMILY SSF69572 125 355 6.67E-14 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD44_RS28130 a6b9e51ec63b649afd0f622b39dfbb12 378 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 243 373 1.1E-11 T 28-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain SMD44_RS28130 a6b9e51ec63b649afd0f622b39dfbb12 378 Gene3D G3DSA:3.40.50.720 120 360 3.3E-27 T 28-03-2018 SMD44_RS28130 a6b9e51ec63b649afd0f622b39dfbb12 378 Pfam PF00899 ThiF family 129 355 5.1E-14 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD44_RS13540 82ba989fb41797822e06d0804d12cf04 346 SUPERFAMILY SSF53807 37 123 4.02E-70 T 28-03-2018 SMD44_RS13540 82ba989fb41797822e06d0804d12cf04 346 SUPERFAMILY SSF53807 166 344 4.02E-70 T 28-03-2018 SMD44_RS13540 82ba989fb41797822e06d0804d12cf04 346 Gene3D G3DSA:3.40.50.1980 27 223 8.1E-45 T 28-03-2018 SMD44_RS13540 82ba989fb41797822e06d0804d12cf04 346 Gene3D G3DSA:3.40.50.1980 224 344 3.3E-35 T 28-03-2018 SMD44_RS13540 82ba989fb41797822e06d0804d12cf04 346 Pfam PF01297 Zinc-uptake complex component A periplasmic 41 341 2.9E-72 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 Pfam PF12029 Domain of unknown function (DUF3516) 384 844 1.1E-217 T 28-03-2018 IPR021904 Protein of unknown function DUF3516 SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 Gene3D G3DSA:3.40.50.300 28 211 2.3E-27 T 28-03-2018 SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 Pfam PF00271 Helicase conserved C-terminal domain 251 373 3.2E-6 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 SUPERFAMILY SSF52540 54 260 1.3E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 SUPERFAMILY SSF52540 293 385 1.3E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 Pfam PF00270 DEAD/DEAH box helicase 43 189 3.3E-10 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 Gene3D G3DSA:3.40.50.300 218 416 2.2E-18 T 28-03-2018 SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 SMART SM00487 37 222 1.3E-16 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS39410 baf683b999f1853ccf9c8f1530dc5945 847 SMART SM00490 287 373 1.2E-12 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS14345 860850c04f370b602d05ae0f80650255 136 SUPERFAMILY SSF55874 37 119 2.74E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14345 860850c04f370b602d05ae0f80650255 136 Gene3D G3DSA:3.30.565.10 6 133 1.3E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14345 860850c04f370b602d05ae0f80650255 136 Pfam PF13581 Histidine kinase-like ATPase domain 15 113 7.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 Pfam PF03466 LysR substrate binding domain 149 338 7.7E-10 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 SUPERFAMILY SSF53850 148 343 6.88E-12 T 28-03-2018 SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 48 106 2.2E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 Gene3D G3DSA:3.40.190.10 225 342 4.1E-5 T 28-03-2018 SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 73 83 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 83 94 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 62 73 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 Gene3D G3DSA:3.40.190.10 129 224 1.8E-9 T 28-03-2018 SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 SUPERFAMILY SSF46785 46 127 3.63E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16020 ca9200b1be81374ca47f236b2cde8f12 366 Gene3D G3DSA:1.10.10.10 40 127 9.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30175 78f5ebef1a97b20bb10c2589394549d9 201 Pfam PF03029 Conserved hypothetical ATP binding protein 29 195 1.7E-27 T 28-03-2018 IPR004130 GPN-loop GTPase SMD44_RS30175 78f5ebef1a97b20bb10c2589394549d9 201 SUPERFAMILY SSF52540 24 198 6.44E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30175 78f5ebef1a97b20bb10c2589394549d9 201 Gene3D G3DSA:3.40.50.300 14 200 1.5E-18 T 28-03-2018 SMD44_RS34915 f88909370aaa66a74709592554370840 509 Gene3D G3DSA:3.20.20.300 15 367 8.5E-80 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS34915 f88909370aaa66a74709592554370840 509 PRINTS PR00133 Glycosyl hydrolase family 3 signature 91 110 3.4E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS34915 f88909370aaa66a74709592554370840 509 PRINTS PR00133 Glycosyl hydrolase family 3 signature 169 185 3.4E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS34915 f88909370aaa66a74709592554370840 509 PRINTS PR00133 Glycosyl hydrolase family 3 signature 245 263 3.4E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS34915 f88909370aaa66a74709592554370840 509 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 38 327 2.3E-70 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS34915 f88909370aaa66a74709592554370840 509 SUPERFAMILY SSF51445 30 335 1.58E-78 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS15950 33f735096e4575a6683a71bee5d2d3a6 205 SUPERFAMILY SSF88946 39 130 3.92E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15950 33f735096e4575a6683a71bee5d2d3a6 205 Pfam PF04545 Sigma-70, region 4 147 195 1.3E-13 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15950 33f735096e4575a6683a71bee5d2d3a6 205 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 70 102 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15950 33f735096e4575a6683a71bee5d2d3a6 205 SUPERFAMILY SSF88659 129 200 4.14E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15950 33f735096e4575a6683a71bee5d2d3a6 205 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 44 197 6.7E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15950 33f735096e4575a6683a71bee5d2d3a6 205 Gene3D G3DSA:1.10.1740.10 37 119 1.7E-21 T 28-03-2018 SMD44_RS15950 33f735096e4575a6683a71bee5d2d3a6 205 Pfam PF04542 Sigma-70 region 2 47 115 9.8E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15950 33f735096e4575a6683a71bee5d2d3a6 205 Gene3D G3DSA:1.10.10.10 142 204 9.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20825 58dc37e23ec24c8c303ca3144c87dd7e 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 356 49.385 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD44_RS20825 58dc37e23ec24c8c303ca3144c87dd7e 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD44_RS20825 58dc37e23ec24c8c303ca3144c87dd7e 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 353 2.2E-87 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD44_RS20825 58dc37e23ec24c8c303ca3144c87dd7e 359 Gene3D G3DSA:3.40.640.10 44 250 1.8E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS20825 58dc37e23ec24c8c303ca3144c87dd7e 359 SUPERFAMILY SSF53383 26 351 3.16E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS20825 58dc37e23ec24c8c303ca3144c87dd7e 359 Pfam PF00155 Aminotransferase class I and II 33 348 2.8E-50 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS20825 58dc37e23ec24c8c303ca3144c87dd7e 359 Gene3D G3DSA:3.90.1150.10 251 356 3.5E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS20825 58dc37e23ec24c8c303ca3144c87dd7e 359 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 8 357 50.116 T 28-03-2018 IPR024892 Putative phenylalanine aminotransferase SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Gene3D G3DSA:1.10.45.10 489 528 7.2E-12 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 SUPERFAMILY SSF46548 504 647 1.62E-9 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Gene3D G3DSA:3.30.43.10 4 101 9.3E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 628 639 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Gene3D G3DSA:3.30.465.10 102 300 1.6E-39 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 SUPERFAMILY SSF55103 254 532 2.78E-51 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 SUPERFAMILY SSF56176 18 278 1.12E-57 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Pfam PF13183 4Fe-4S dicluster domain 565 642 6.5E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Pfam PF02913 FAD linked oxidases, C-terminal domain 277 528 9.6E-52 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Gene3D G3DSA:1.10.1060.10 534 663 5.6E-13 T 28-03-2018 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Pfam PF01565 FAD binding domain 52 186 6.8E-40 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Pfam PF02754 Cysteine-rich domain 749 821 0.042 T 28-03-2018 IPR004017 Cysteine-rich domain SMD44_RS05120 b824a9969558bbef5f386e30260ec214 979 Pfam PF02754 Cysteine-rich domain 871 955 0.022 T 28-03-2018 IPR004017 Cysteine-rich domain SMD44_RS16055 b261a7c9b329ae7fb6cbddc2ce1ed048 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS16055 b261a7c9b329ae7fb6cbddc2ce1ed048 229 SUPERFAMILY SSF52540 1 221 4.18E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16055 b261a7c9b329ae7fb6cbddc2ce1ed048 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 4.9E-87 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 SMD44_RS16055 b261a7c9b329ae7fb6cbddc2ce1ed048 229 Pfam PF00005 ABC transporter 19 166 6.9E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS16055 b261a7c9b329ae7fb6cbddc2ce1ed048 229 SMART SM00382 28 215 5.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16055 b261a7c9b329ae7fb6cbddc2ce1ed048 229 Gene3D G3DSA:3.40.50.300 1 225 8.8E-70 T 28-03-2018 SMD44_RS15080 36e03d098e7cd4a8d948b5abaf90d7a3 235 SMART SM00862 156 231 8.6E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS15080 36e03d098e7cd4a8d948b5abaf90d7a3 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 229 1.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS15080 36e03d098e7cd4a8d948b5abaf90d7a3 235 Gene3D G3DSA:3.40.50.2300 3 127 8.5E-34 T 28-03-2018 SMD44_RS15080 36e03d098e7cd4a8d948b5abaf90d7a3 235 Gene3D G3DSA:1.10.10.10 128 235 1.4E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15080 36e03d098e7cd4a8d948b5abaf90d7a3 235 Pfam PF00072 Response regulator receiver domain 7 114 5.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS15080 36e03d098e7cd4a8d948b5abaf90d7a3 235 SUPERFAMILY SSF52172 3 176 1.57E-37 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS15080 36e03d098e7cd4a8d948b5abaf90d7a3 235 SMART SM00448 5 115 1.1E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16125 d41d09e1da506c21c643cb814eecaaa4 1164 SUPERFAMILY SSF53448 3 231 5.63E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16125 d41d09e1da506c21c643cb814eecaaa4 1164 SUPERFAMILY SSF53756 916 1163 2.98E-13 T 28-03-2018 SMD44_RS16125 d41d09e1da506c21c643cb814eecaaa4 1164 Pfam PF00535 Glycosyl transferase family 2 6 180 3.0E-31 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS16125 d41d09e1da506c21c643cb814eecaaa4 1164 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 822 1163 2.6E-90 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 SMD44_RS16125 d41d09e1da506c21c643cb814eecaaa4 1164 Gene3D G3DSA:3.90.550.10 1 269 3.5E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SUPERFAMILY SSF51126 322 495 5.57E-16 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 Pfam PF12708 Pectate lyase superfamily protein 31 293 3.7E-9 T 28-03-2018 IPR024535 Pectate lyase superfamily protein SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 Gene3D G3DSA:2.160.20.10 416 536 1.9E-5 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 Pfam PF13229 Right handed beta helix region 354 489 2.8E-14 T 28-03-2018 SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 Gene3D G3DSA:2.160.20.10 27 415 8.2E-48 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 376 398 74.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 254 276 1300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 399 421 76.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 446 483 1300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 277 298 7000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 147 170 1200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 321 345 5700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 351 375 630.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 422 444 31.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SMART SM00710 218 247 3400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS24820 843016ae05d28914f9fb6f18e233a754 543 SUPERFAMILY SSF51126 28 340 1.8E-31 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 Gene3D G3DSA:3.10.170.10 289 456 3.6E-41 T 28-03-2018 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 Gene3D G3DSA:1.10.390.10 457 610 2.5E-30 T 28-03-2018 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 Gene3D G3DSA:2.130.10.150 643 771 0.084 T 28-03-2018 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 Gene3D G3DSA:2.130.10.150 776 947 0.0012 T 28-03-2018 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 455 609 6.8E-30 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 SUPERFAMILY SSF55486 290 609 4.58E-61 T 28-03-2018 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 291 452 5.2E-37 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 443 459 3.4E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 535 551 3.4E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 408 428 3.4E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS08875 63d4965c155470cae6272b822b6271a4 952 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 464 475 3.4E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS04205 549ddacb2cd395e2e6fad387fb10588c 52 Pfam PF01381 Helix-turn-helix 3 50 1.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS04205 549ddacb2cd395e2e6fad387fb10588c 52 SUPERFAMILY SSF47413 2 51 1.57E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS04205 549ddacb2cd395e2e6fad387fb10588c 52 SMART SM00530 3 50 0.0039 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS04205 549ddacb2cd395e2e6fad387fb10588c 52 Gene3D G3DSA:1.10.260.40 1 52 7.8E-13 T 28-03-2018 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 133 5.7E-30 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 Gene3D G3DSA:3.40.120.10 162 268 8.2E-36 T 28-03-2018 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 Gene3D G3DSA:3.30.310.50 370 456 8.4E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 SUPERFAMILY SSF53738 158 260 3.92E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 Gene3D G3DSA:3.40.120.10 269 369 8.7E-27 T 28-03-2018 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 SUPERFAMILY SSF53738 8 170 5.49E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 4.2E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 253 4.2E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 4.2E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 209 222 4.2E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 SUPERFAMILY SSF53738 264 369 3.92E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 455 9.4E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 SUPERFAMILY SSF55957 376 456 8.5E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 Gene3D G3DSA:3.40.120.10 4 161 5.1E-31 T 28-03-2018 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 258 2.0E-26 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS16400 47824555b301edbbfa26d8d9042aae65 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 267 373 7.8E-26 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS32625 dede2583691f7abfbda5edea916c9da1 252 SUPERFAMILY SSF52317 10 237 4.27E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS32625 dede2583691f7abfbda5edea916c9da1 252 Pfam PF00117 Glutamine amidotransferase class-I 40 230 1.8E-11 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS32625 dede2583691f7abfbda5edea916c9da1 252 Gene3D G3DSA:3.40.50.880 5 239 8.0E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS03970 b8002f9dfc5bff5e8b19f752c74ee9b6 277 Pfam PF03473 MOSC domain 147 273 2.2E-33 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 SMD44_RS03970 b8002f9dfc5bff5e8b19f752c74ee9b6 277 SUPERFAMILY SSF50800 4 55 2.93E-18 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMD44_RS03970 b8002f9dfc5bff5e8b19f752c74ee9b6 277 SUPERFAMILY SSF50800 156 276 2.93E-18 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMD44_RS03970 b8002f9dfc5bff5e8b19f752c74ee9b6 277 Pfam PF03476 MOSC N-terminal beta barrel domain 8 120 4.2E-22 T 28-03-2018 IPR005303 MOSC, N-terminal beta barrel SMD44_RS03970 b8002f9dfc5bff5e8b19f752c74ee9b6 277 Gene3D G3DSA:2.40.33.20 2 277 5.8E-51 T 28-03-2018 SMD44_RS03970 b8002f9dfc5bff5e8b19f752c74ee9b6 277 SUPERFAMILY SSF141673 9 137 8.11E-27 T 28-03-2018 SMD44_RS02800 dff1035d97322c2f71450d75a4da78fb 302 Gene3D G3DSA:3.20.20.70 7 300 2.3E-78 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS02800 dff1035d97322c2f71450d75a4da78fb 302 SMART SM01130 11 297 5.6E-85 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS02800 dff1035d97322c2f71450d75a4da78fb 302 SUPERFAMILY SSF51569 9 295 2.2E-76 T 28-03-2018 SMD44_RS02800 dff1035d97322c2f71450d75a4da78fb 302 Pfam PF00701 Dihydrodipicolinate synthetase family 13 293 4.7E-49 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS02800 dff1035d97322c2f71450d75a4da78fb 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 9.1E-10 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS02800 dff1035d97322c2f71450d75a4da78fb 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 9.1E-10 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS02800 dff1035d97322c2f71450d75a4da78fb 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 9.1E-10 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS02800 dff1035d97322c2f71450d75a4da78fb 302 PIRSF PIRSF001365 8 300 7.8E-72 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 SUPERFAMILY SSF53187 212 433 4.83E-92 T 28-03-2018 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 SUPERFAMILY SSF53187 9 91 4.83E-92 T 28-03-2018 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 18 430 1.3E-119 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 399 414 2.1E-36 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 310 326 2.1E-36 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 80 96 2.1E-36 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 267 285 2.1E-36 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 113 133 2.1E-36 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 SUPERFAMILY SSF101821 92 211 5.04E-29 T 28-03-2018 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 Gene3D G3DSA:3.40.630.10 185 434 3.5E-72 T 28-03-2018 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 Gene3D G3DSA:3.40.630.10 7 133 9.2E-34 T 28-03-2018 SMD44_RS21860 0ecacbc25a1ece1abe4efd68821556a0 434 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 434 57.428 T 28-03-2018 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 SMD44_RS08740 847cd83c3b1269e697f8a1803242cdb8 364 Gene3D G3DSA:3.40.50.300 96 321 1.9E-16 T 28-03-2018 SMD44_RS08740 847cd83c3b1269e697f8a1803242cdb8 364 SUPERFAMILY SSF52540 177 314 3.12E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08740 847cd83c3b1269e697f8a1803242cdb8 364 SMART SM00382 178 315 1.1E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS08740 847cd83c3b1269e697f8a1803242cdb8 364 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 182 312 4.9E-11 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 SUPERFAMILY SSF56425 242 359 1.03E-37 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 362 384 2.0E-10 T 28-03-2018 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 2.0E-10 T 28-03-2018 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 Gene3D G3DSA:3.50.50.60 8 304 1.2E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 Gene3D G3DSA:1.20.58.100 437 550 2.2E-31 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 19 529 5.5E-162 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 1.9E-6 T 28-03-2018 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 384 1.9E-6 T 28-03-2018 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 Gene3D G3DSA:3.50.50.60 307 416 9.4E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 SUPERFAMILY SSF51905 363 422 8.07E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 SUPERFAMILY SSF51905 6 271 8.07E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 Pfam PF02910 Fumarate reductase flavoprotein C-term 448 548 2.7E-19 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 SUPERFAMILY SSF46977 442 549 6.15E-30 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 PIRSF PIRSF000171 15 562 3.2E-41 T 28-03-2018 SMD44_RS23830 d76b613dc0215994a391996fd6a60baa 567 Pfam PF00890 FAD binding domain 20 399 2.1E-95 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS06345 848f9474c63dba78f372b80948441157 234 Gene3D G3DSA:1.20.1660.10 16 137 1.4E-27 T 28-03-2018 SMD44_RS06345 848f9474c63dba78f372b80948441157 234 Pfam PF08713 DNA alkylation repair enzyme 21 232 9.5E-65 T 28-03-2018 IPR014825 DNA alkylation repair enzyme SMD44_RS06345 848f9474c63dba78f372b80948441157 234 Gene3D G3DSA:1.25.40.290 138 234 6.6E-24 T 28-03-2018 SMD44_RS06345 848f9474c63dba78f372b80948441157 234 SUPERFAMILY SSF48371 24 232 6.33E-53 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS24250 78634c4915a7ad7fba76100513ec821d 180 SUPERFAMILY SSF55729 9 164 3.06E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS24250 78634c4915a7ad7fba76100513ec821d 180 Gene3D G3DSA:3.40.630.30 3 175 3.1E-15 T 28-03-2018 SMD44_RS24250 78634c4915a7ad7fba76100513ec821d 180 Pfam PF00583 Acetyltransferase (GNAT) family 42 157 1.3E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS23805 535982637d0bcec88ded667e22cba2a5 369 SUPERFAMILY SSF46785 282 358 8.19E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23805 535982637d0bcec88ded667e22cba2a5 369 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 321 336 7.0E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS23805 535982637d0bcec88ded667e22cba2a5 369 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 289 304 7.0E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS23805 535982637d0bcec88ded667e22cba2a5 369 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 336 351 7.0E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS23805 535982637d0bcec88ded667e22cba2a5 369 Gene3D G3DSA:1.10.10.10 273 367 4.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23805 535982637d0bcec88ded667e22cba2a5 369 Pfam PF12840 Helix-turn-helix domain 290 345 1.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23805 535982637d0bcec88ded667e22cba2a5 369 SMART SM00418 287 365 4.0E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 PRINTS PR01467 Bacterial arginine repressor signature 55 70 6.0E-26 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 PRINTS PR01467 Bacterial arginine repressor signature 116 129 6.0E-26 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 PRINTS PR01467 Bacterial arginine repressor signature 146 161 6.0E-26 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 PRINTS PR01467 Bacterial arginine repressor signature 39 52 6.0E-26 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 120 155 2.0E-13 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 Hamap MF_00173 Arginine repressor [argR]. 1 180 55.479 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 TIGRFAM TIGR01529 argR_whole: arginine repressor 23 176 5.2E-43 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 Pfam PF01316 Arginine repressor, DNA binding domain 20 87 3.6E-24 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 Gene3D G3DSA:3.30.1360.40 102 173 1.3E-28 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 Gene3D G3DSA:1.10.10.10 13 86 2.2E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 SUPERFAMILY SSF46785 19 88 1.75E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 SUPERFAMILY SSF55252 110 175 1.83E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMD44_RS07785 410b3d960922ccff9433fe03200e5543 181 Pfam PF02863 Arginine repressor, C-terminal domain 110 173 7.6E-24 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMD44_RS06560 de70f8e93749f160fec86746167c6a73 275 Gene3D G3DSA:3.10.310.10 133 263 1.7E-33 T 28-03-2018 SMD44_RS06560 de70f8e93749f160fec86746167c6a73 275 Gene3D G3DSA:3.10.310.10 4 132 1.2E-34 T 28-03-2018 SMD44_RS06560 de70f8e93749f160fec86746167c6a73 275 PIRSF PIRSF016184 4 275 2.5E-50 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD44_RS06560 de70f8e93749f160fec86746167c6a73 275 Pfam PF02567 Phenazine biosynthesis-like protein 12 271 5.2E-62 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD44_RS06560 de70f8e93749f160fec86746167c6a73 275 SUPERFAMILY SSF54506 7 273 5.92E-72 T 28-03-2018 SMD44_RS06560 de70f8e93749f160fec86746167c6a73 275 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 9 272 2.3E-37 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD44_RS25195 6e4e4dfa999a5c7e40b66a57c90caef8 203 Pfam PF07336 Putative stress-induced transcription regulator 14 139 3.3E-20 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS25195 6e4e4dfa999a5c7e40b66a57c90caef8 203 SUPERFAMILY SSF160904 9 184 2.88E-43 T 28-03-2018 SMD44_RS25195 6e4e4dfa999a5c7e40b66a57c90caef8 203 Pfam PF11706 CGNR zinc finger 143 184 6.0E-18 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS25195 6e4e4dfa999a5c7e40b66a57c90caef8 203 Gene3D G3DSA:1.10.3300.10 5 188 3.8E-50 T 28-03-2018 IPR023286 ABATE domain SMD44_RS10145 d31147439846d708d3fbf379d1c451ee 311 Pfam PF03668 P-loop ATPase protein family 29 311 1.2E-110 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 SMD44_RS10145 d31147439846d708d3fbf379d1c451ee 311 Gene3D G3DSA:3.40.50.300 18 185 2.5E-12 T 28-03-2018 SMD44_RS10145 d31147439846d708d3fbf379d1c451ee 311 SUPERFAMILY SSF52540 29 180 6.93E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10145 d31147439846d708d3fbf379d1c451ee 311 PIRSF PIRSF005052 28 311 5.8E-111 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 SMD44_RS10145 d31147439846d708d3fbf379d1c451ee 311 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 28 310 41.326 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 SMD44_RS26680 37488d94af01c7639fda8376cc0ce21b 434 Pfam PF08282 haloacid dehalogenase-like hydrolase 355 418 7.1E-8 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS26680 37488d94af01c7639fda8376cc0ce21b 434 SUPERFAMILY SSF53448 19 156 1.51E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS26680 37488d94af01c7639fda8376cc0ce21b 434 SUPERFAMILY SSF53448 187 263 1.51E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS26680 37488d94af01c7639fda8376cc0ce21b 434 Pfam PF02348 Cytidylyltransferase 22 154 4.1E-22 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 SMD44_RS26680 37488d94af01c7639fda8376cc0ce21b 434 Gene3D G3DSA:3.40.50.1000 274 433 4.1E-23 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS26680 37488d94af01c7639fda8376cc0ce21b 434 Gene3D G3DSA:3.90.550.10 17 265 2.0E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS26680 37488d94af01c7639fda8376cc0ce21b 434 SUPERFAMILY SSF56784 279 428 4.96E-31 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 Pfam PF13185 GAF domain 55 192 5.6E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 Pfam PF13185 GAF domain 226 360 6.3E-16 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 SUPERFAMILY SSF55781 225 386 4.36E-23 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 Gene3D G3DSA:3.30.450.40 11 200 6.0E-35 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 Pfam PF07730 Histidine kinase 377 439 3.2E-10 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 SMART SM00065 54 201 9.5E-18 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 SMART SM00065 222 369 7.7E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 SUPERFAMILY SSF55781 36 219 3.49E-38 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 Gene3D G3DSA:3.30.565.10 449 574 1.2E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 Gene3D G3DSA:3.30.450.40 201 372 1.9E-28 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 SMART SM00387 483 574 0.0052 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS39135 1dddbc373e165d0deb41eae1c3210c75 577 SUPERFAMILY SSF55874 480 570 1.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 423 38.957 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 PIRSF PIRSF001529 1 426 5.0E-139 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 1.7E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 1.7E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 1.7E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 1.7E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 1.7E-28 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 1.6E-22 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 418 2.9E-131 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 Gene3D G3DSA:3.30.930.10 104 423 2.5E-85 T 28-03-2018 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 401 7.1E-29 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 Gene3D G3DSA:1.10.287.40 1 102 3.2E-19 T 28-03-2018 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 SUPERFAMILY SSF46589 2 111 7.85E-22 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 SMD44_RS20730 b2b22c9eb4ed120502e571e2861b01dd 429 SUPERFAMILY SSF55681 131 421 1.67E-84 T 28-03-2018 SMD44_RS22660 c453a840df04793f58f4796bbccbce9e 172 Gene3D G3DSA:1.10.10.10 1 166 3.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22660 c453a840df04793f58f4796bbccbce9e 172 Pfam PF12802 MarR family 34 93 1.5E-10 T 28-03-2018 SMD44_RS22660 c453a840df04793f58f4796bbccbce9e 172 SUPERFAMILY SSF46785 19 125 2.64E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14740 1fb5df74201e3a3077062b13e3e6c5b0 333 SUPERFAMILY SSF46689 241 286 2.46E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS14740 1fb5df74201e3a3077062b13e3e6c5b0 333 Gene3D G3DSA:1.10.10.60 187 243 2.6E-8 T 28-03-2018 SMD44_RS14740 1fb5df74201e3a3077062b13e3e6c5b0 333 Pfam PF12833 Helix-turn-helix domain 211 286 1.3E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS14740 1fb5df74201e3a3077062b13e3e6c5b0 333 SMART SM00342 205 287 2.3E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS14740 1fb5df74201e3a3077062b13e3e6c5b0 333 Gene3D G3DSA:1.10.10.60 244 291 3.3E-10 T 28-03-2018 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 SMART SM00421 147 204 3.2E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 Gene3D G3DSA:1.10.10.10 116 213 3.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 8.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 8.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 8.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 SUPERFAMILY SSF46894 144 210 9.52E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 Gene3D G3DSA:3.40.50.2300 1 115 1.3E-10 T 28-03-2018 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 8.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36250 d6f6e493af3c0d3ceac64ff847955e88 224 SUPERFAMILY SSF52172 1 125 2.65E-8 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS42755 2f782fc23296d31968fbd59573fcfcb8 205 Gene3D G3DSA:3.40.50.2020 36 205 2.3E-24 T 28-03-2018 SMD44_RS42755 2f782fc23296d31968fbd59573fcfcb8 205 Pfam PF00156 Phosphoribosyl transferase domain 50 173 8.6E-19 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD44_RS42755 2f782fc23296d31968fbd59573fcfcb8 205 SUPERFAMILY SSF53271 40 201 5.24E-23 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS10005 a5c49ae956f56c69a187dab59fb98963 105 Pfam PF00355 Rieske [2Fe-2S] domain 4 89 1.4E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS10005 a5c49ae956f56c69a187dab59fb98963 105 Gene3D G3DSA:2.102.10.10 2 105 3.8E-28 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS10005 a5c49ae956f56c69a187dab59fb98963 105 SUPERFAMILY SSF50022 1 103 4.58E-32 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS37450 da98ce2ed1a098d1944f328ae5abeeff 401 SUPERFAMILY SSF51905 272 353 1.46E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37450 da98ce2ed1a098d1944f328ae5abeeff 401 SUPERFAMILY SSF51905 2 147 1.46E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37450 da98ce2ed1a098d1944f328ae5abeeff 401 Gene3D G3DSA:3.50.50.60 1 352 9.7E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37070 1b59f454042e2e4c762e2605dd49e212 779 Gene3D G3DSA:2.70.98.10 36 334 1.4E-98 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMD44_RS37070 1b59f454042e2e4c762e2605dd49e212 779 SUPERFAMILY SSF48208 278 743 4.59E-25 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS37070 1b59f454042e2e4c762e2605dd49e212 779 Gene3D G3DSA:3.30.2080.10 625 774 1.3E-46 T 28-03-2018 SMD44_RS37070 1b59f454042e2e4c762e2605dd49e212 779 Pfam PF07971 Glycosyl hydrolase family 92 250 761 7.0E-142 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 SMD44_RS37070 1b59f454042e2e4c762e2605dd49e212 779 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 35 764 8.0E-167 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SMD44_RS37070 1b59f454042e2e4c762e2605dd49e212 779 Gene3D G3DSA:1.20.1610.10 454 624 5.5E-47 T 28-03-2018 SMD44_RS37070 1b59f454042e2e4c762e2605dd49e212 779 Gene3D G3DSA:1.20.1050.60 357 450 2.9E-24 T 28-03-2018 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Gene3D G3DSA:2.130.10.120 732 976 1.6E-14 T 28-03-2018 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Gene3D G3DSA:2.80.10.50 1226 1284 4.3E-12 T 28-03-2018 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Gene3D G3DSA:3.40.50.300 92 549 8.6E-8 T 28-03-2018 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SMART SM00320 578 616 87.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SMART SM00320 1199 1247 0.014 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SMART SM00320 849 896 220.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SMART SM00320 1163 1196 3.4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SMART SM00320 771 810 140.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Gene3D G3DSA:2.130.10.10 977 1144 1.1E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Gene3D G3DSA:2.130.10.10 552 730 3.0E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Gene3D G3DSA:1.10.260.40 2 82 2.7E-7 T 28-03-2018 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SUPERFAMILY SSF50998 835 912 5.34E-29 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SUPERFAMILY SSF50998 1034 1282 5.34E-29 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SUPERFAMILY SSF52540 104 313 1.71E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Pfam PF00400 WD domain, G-beta repeat 1220 1247 0.067 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Pfam PF00400 WD domain, G-beta repeat 1173 1196 0.07 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SUPERFAMILY SSF50998 761 862 2.04E-16 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SUPERFAMILY SSF50998 576 712 2.04E-16 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 Gene3D G3DSA:2.130.10.120 1145 1225 2.4E-10 T 28-03-2018 SMD44_RS00800 2a0cc74ce170c6f23a992257725ee558 1326 SMART SM00530 7 63 3.3E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS14325 00ee8429c4180b7238e8c482c7055f6b 397 Pfam PF07690 Major Facilitator Superfamily 29 359 2.9E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS14325 00ee8429c4180b7238e8c482c7055f6b 397 Gene3D G3DSA:1.20.1250.20 16 207 1.4E-25 T 28-03-2018 SMD44_RS14325 00ee8429c4180b7238e8c482c7055f6b 397 SUPERFAMILY SSF103473 10 392 3.66E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS14325 00ee8429c4180b7238e8c482c7055f6b 397 Gene3D G3DSA:1.20.1250.20 209 395 4.0E-21 T 28-03-2018 SMD44_RS03615 4a3bd4c5e443e73d71ff0e17123bcc3d 933 Gene3D G3DSA:3.30.420.40 383 591 6.4E-18 T 28-03-2018 SMD44_RS03615 4a3bd4c5e443e73d71ff0e17123bcc3d 933 Gene3D G3DSA:3.30.420.40 129 382 7.4E-13 T 28-03-2018 SMD44_RS03615 4a3bd4c5e443e73d71ff0e17123bcc3d 933 SUPERFAMILY SSF53067 373 589 6.24E-13 T 28-03-2018 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 SUPERFAMILY SSF52172 5 128 1.37E-33 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 SUPERFAMILY SSF46894 151 222 6.8E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 1.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 SMART SM00448 5 120 9.8E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 214 2.2E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 Gene3D G3DSA:3.40.50.2300 4 131 1.1E-34 T 28-03-2018 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 Pfam PF00072 Response regulator receiver domain 7 121 2.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 Gene3D G3DSA:1.10.10.10 132 226 1.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13670 899196b976b06de86fec0e3b3695a968 228 SMART SM00421 159 216 9.0E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 Pfam PF13377 Periplasmic binding protein-like domain 170 329 1.6E-36 T 28-03-2018 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 SUPERFAMILY SSF53822 62 333 1.02E-76 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 Gene3D G3DSA:3.40.50.2300 57 176 1.5E-38 T 28-03-2018 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 SUPERFAMILY SSF47413 4 61 7.79E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 SMART SM00354 3 73 8.6E-31 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 Gene3D G3DSA:1.10.260.40 4 56 1.3E-25 T 28-03-2018 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 2.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 2.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 50 6.3E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS14770 b9c75ae4a5aed045c156e928ec2ada4c 355 Gene3D G3DSA:3.40.50.2300 177 314 1.6E-42 T 28-03-2018 SMD44_RS08465 06b8f4db560fe6130aa789eea85e2287 240 Gene3D G3DSA:3.90.420.10 31 236 1.4E-51 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS08465 06b8f4db560fe6130aa789eea85e2287 240 SUPERFAMILY SSF56524 64 232 4.45E-51 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS08465 06b8f4db560fe6130aa789eea85e2287 240 Pfam PF00174 Oxidoreductase molybdopterin binding domain 71 217 3.3E-37 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS12095 cd3eada31b8885d93dbeb1816ffda997 434 ProSitePatterns PS00216 Sugar transport proteins signature 1. 61 77 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS12095 cd3eada31b8885d93dbeb1816ffda997 434 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 6 392 7.1E-103 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 SMD44_RS12095 cd3eada31b8885d93dbeb1816ffda997 434 SUPERFAMILY SSF103473 6 400 1.57E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12095 cd3eada31b8885d93dbeb1816ffda997 434 Pfam PF07690 Major Facilitator Superfamily 19 358 2.0E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS12095 cd3eada31b8885d93dbeb1816ffda997 434 Gene3D G3DSA:1.20.1250.20 3 193 1.3E-30 T 28-03-2018 SMD44_RS12095 cd3eada31b8885d93dbeb1816ffda997 434 Gene3D G3DSA:1.20.1250.20 196 409 2.4E-16 T 28-03-2018 SMD44_RS10850 3f430c184937090f4b69f4ab63eff3ce 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMD44_RS10850 3f430c184937090f4b69f4ab63eff3ce 197 Gene3D G3DSA:3.30.230.40 1 89 4.2E-33 T 28-03-2018 SMD44_RS10850 3f430c184937090f4b69f4ab63eff3ce 197 SUPERFAMILY SSF54211 3 86 1.24E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS10850 3f430c184937090f4b69f4ab63eff3ce 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 197 41.316 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMD44_RS10850 3f430c184937090f4b69f4ab63eff3ce 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMD44_RS10850 3f430c184937090f4b69f4ab63eff3ce 197 SUPERFAMILY SSF54211 88 181 4.43E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS10850 3f430c184937090f4b69f4ab63eff3ce 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 176 1.0E-61 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMD44_RS10850 3f430c184937090f4b69f4ab63eff3ce 197 Gene3D G3DSA:3.30.230.40 91 197 2.1E-31 T 28-03-2018 SMD44_RS20715 8038a4d3d8a08a552746cb6fe5866f10 725 Gene3D G3DSA:2.60.40.1220 43 139 3.3E-27 T 28-03-2018 SMD44_RS20715 8038a4d3d8a08a552746cb6fe5866f10 725 SUPERFAMILY SSF81296 43 138 6.79E-23 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS20715 8038a4d3d8a08a552746cb6fe5866f10 725 Pfam PF05425 Copper resistance protein D 349 428 7.6E-17 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 SMD44_RS20715 8038a4d3d8a08a552746cb6fe5866f10 725 Pfam PF04234 CopC domain 44 138 3.9E-23 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 SMD44_RS09505 193d60ee4d3c4c87684a2f88201d37ef 251 Gene3D G3DSA:3.40.50.720 1 249 6.2E-53 T 28-03-2018 SMD44_RS09505 193d60ee4d3c4c87684a2f88201d37ef 251 SUPERFAMILY SSF51735 1 247 1.53E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09505 193d60ee4d3c4c87684a2f88201d37ef 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.7E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09505 193d60ee4d3c4c87684a2f88201d37ef 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09505 193d60ee4d3c4c87684a2f88201d37ef 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.7E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09505 193d60ee4d3c4c87684a2f88201d37ef 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.7E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09505 193d60ee4d3c4c87684a2f88201d37ef 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 3.1E-45 T 28-03-2018 SMD44_RS36355 68b96008cd56c83030df9b9c4a30312e 508 SUPERFAMILY SSF52540 115 314 7.45E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS36355 68b96008cd56c83030df9b9c4a30312e 508 SMART SM00530 21 77 2.1E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS36355 68b96008cd56c83030df9b9c4a30312e 508 Gene3D G3DSA:3.40.50.300 145 487 4.8E-6 T 28-03-2018 SMD44_RS36355 68b96008cd56c83030df9b9c4a30312e 508 Gene3D G3DSA:3.40.50.300 108 144 1.8E-5 T 28-03-2018 SMD44_RS36355 68b96008cd56c83030df9b9c4a30312e 508 Gene3D G3DSA:1.10.260.40 11 92 7.9E-8 T 28-03-2018 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 SUPERFAMILY SSF69075 420 521 1.57E-15 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 184 278 4.7E-19 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 Gene3D G3DSA:1.10.1200.70 444 521 6.0E-21 T 28-03-2018 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 279 6.1E-79 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 518 25.396 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 SUPERFAMILY SSF69742 1 158 4.05E-44 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 Gene3D G3DSA:3.40.50.720 183 443 2.7E-27 T 28-03-2018 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 3.0E-43 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 SUPERFAMILY SSF51735 178 274 3.36E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 422 520 7.6E-19 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD44_RS24145 9b886c0d9db651a73fcbed0e3764de18 555 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 Pfam PF13424 Tetratricopeptide repeat 676 740 7.4E-8 T 28-03-2018 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 Pfam PF13424 Tetratricopeptide repeat 749 821 2.1E-10 T 28-03-2018 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SUPERFAMILY SSF48452 675 784 9.25E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SMART SM00028 751 784 32.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SMART SM00028 871 904 0.12 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SMART SM00028 831 864 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SMART SM00028 711 744 0.81 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SMART SM00028 959 992 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SMART SM00028 791 824 0.31 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 Gene3D G3DSA:1.25.40.10 721 932 1.5E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 Gene3D G3DSA:1.25.40.10 933 1061 0.01 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 Gene3D G3DSA:1.10.150.200 637 720 0.0022 T 28-03-2018 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 Gene3D G3DSA:3.40.50.300 202 377 7.1E-15 T 28-03-2018 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 Pfam PF00931 NB-ARC domain 245 439 1.4E-7 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 Pfam PF13432 Tetratricopeptide repeat 837 897 0.0045 T 28-03-2018 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 PRINTS PR00364 Disease resistance protein signature 336 350 1.7E-8 T 28-03-2018 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 PRINTS PR00364 Disease resistance protein signature 425 439 1.7E-8 T 28-03-2018 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 PRINTS PR00364 Disease resistance protein signature 250 265 1.7E-8 T 28-03-2018 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SUPERFAMILY SSF48452 751 911 2.91E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS27180 adc8bfa562cf7ba963f388eacdad76e4 1088 SUPERFAMILY SSF52540 217 452 2.56E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14625 231dfe6edce3350e56354c2bfd305714 691 Pfam PF01926 50S ribosome-binding GTPase 211 329 4.0E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS14625 231dfe6edce3350e56354c2bfd305714 691 Gene3D G3DSA:3.40.50.300 184 418 1.6E-29 T 28-03-2018 SMD44_RS14625 231dfe6edce3350e56354c2bfd305714 691 SUPERFAMILY SSF52540 201 406 7.0E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27520 c6ab3210c3dd3219ec288a7c644ea289 344 SUPERFAMILY SSF56655 18 330 9.52E-109 T 28-03-2018 SMD44_RS27520 c6ab3210c3dd3219ec288a7c644ea289 344 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 20 331 3.0E-113 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMD44_RS27520 c6ab3210c3dd3219ec288a7c644ea289 344 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 20 327 3.9E-140 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMD44_RS27520 c6ab3210c3dd3219ec288a7c644ea289 344 Gene3D G3DSA:3.30.540.10 171 338 1.0E-53 T 28-03-2018 SMD44_RS27520 c6ab3210c3dd3219ec288a7c644ea289 344 Gene3D G3DSA:3.30.540.10 17 170 1.9E-51 T 28-03-2018 SMD44_RS27520 c6ab3210c3dd3219ec288a7c644ea289 344 PIRSF PIRSF004532 18 338 1.4E-142 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMD44_RS10115 f3fbc9a73defad2fbe4fbfb81cc5cfd1 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 7 259 40.398 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10115 f3fbc9a73defad2fbe4fbfb81cc5cfd1 261 Pfam PF00121 Triosephosphate isomerase 10 256 1.0E-90 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10115 f3fbc9a73defad2fbe4fbfb81cc5cfd1 261 SUPERFAMILY SSF51351 6 258 1.1E-93 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10115 f3fbc9a73defad2fbe4fbfb81cc5cfd1 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 11 250 9.6E-56 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10115 f3fbc9a73defad2fbe4fbfb81cc5cfd1 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 174 184 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10115 f3fbc9a73defad2fbe4fbfb81cc5cfd1 261 Gene3D G3DSA:3.20.20.70 5 261 4.7E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS29175 89f59d3e436f8da7d24b5c8a6f72e4af 249 SUPERFAMILY SSF46894 147 246 1.64E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS29175 89f59d3e436f8da7d24b5c8a6f72e4af 249 Pfam PF00072 Response regulator receiver domain 20 130 2.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS29175 89f59d3e436f8da7d24b5c8a6f72e4af 249 Gene3D G3DSA:3.40.50.2300 5 141 5.9E-39 T 28-03-2018 SMD44_RS29175 89f59d3e436f8da7d24b5c8a6f72e4af 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 171 246 2.2E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS29175 89f59d3e436f8da7d24b5c8a6f72e4af 249 SUPERFAMILY SSF52172 13 137 1.38E-41 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS29175 89f59d3e436f8da7d24b5c8a6f72e4af 249 SMART SM00862 171 246 1.4E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS29175 89f59d3e436f8da7d24b5c8a6f72e4af 249 Gene3D G3DSA:1.10.10.10 142 249 9.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29175 89f59d3e436f8da7d24b5c8a6f72e4af 249 SMART SM00448 18 129 1.7E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Gene3D G3DSA:3.30.565.10 1 140 1.5E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Pfam PF13185 GAF domain 296 431 1.2E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 157 256 8.4E-11 T 28-03-2018 IPR000014 PAS domain SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Gene3D G3DSA:3.30.450.40 440 625 1.6E-23 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 SUPERFAMILY SSF55781 297 435 8.72E-19 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 SUPERFAMILY SSF81606 659 867 4.45E-7 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Gene3D G3DSA:3.30.450.40 289 439 4.1E-19 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Pfam PF00989 PAS fold 157 256 7.8E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 SUPERFAMILY SSF55785 157 251 4.89E-15 T 28-03-2018 IPR000014 PAS domain SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Gene3D G3DSA:3.60.40.10 626 868 4.1E-33 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 SMART SM00091 146 213 4.7E-4 T 28-03-2018 IPR000014 PAS domain SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Pfam PF13492 GAF domain 547 621 1.0E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Gene3D G3DSA:3.30.450.20 155 256 2.5E-13 T 28-03-2018 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 677 867 2.2E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 SMART SM00331 650 867 3.0E-67 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 SUPERFAMILY SSF55781 446 627 1.26E-10 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 Pfam PF13581 Histidine kinase-like ATPase domain 13 125 1.2E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 SMART SM00065 461 629 0.092 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS31105 f2c86b4b4e72e63801cf9565ab237de5 872 SMART SM00065 296 440 7.7E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS06545 17d651572bcf72e456224e6a8765b842 258 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 35 236 7.2E-41 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SMD44_RS06545 17d651572bcf72e456224e6a8765b842 258 SUPERFAMILY SSF53335 45 223 2.61E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS06545 17d651572bcf72e456224e6a8765b842 258 Pfam PF05175 Methyltransferase small domain 78 178 4.1E-12 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMD44_RS06545 17d651572bcf72e456224e6a8765b842 258 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 9 255 1.8E-121 T 28-03-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase SMD44_RS06545 17d651572bcf72e456224e6a8765b842 258 Gene3D G3DSA:1.10.8.10 31 63 8.8E-6 T 28-03-2018 SMD44_RS06545 17d651572bcf72e456224e6a8765b842 258 Gene3D G3DSA:3.40.50.150 64 255 7.0E-39 T 28-03-2018 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 Gene3D G3DSA:3.40.50.300 377 621 7.3E-50 T 28-03-2018 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 SMART SM00382 422 607 2.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 Pfam PF07498 Rho termination factor, N-terminal domain 38 78 4.7E-12 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 SMART SM00959 37 78 6.6E-12 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 Hamap MF_01884 Transcription termination factor Rho [rho]. 291 671 205.079 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 SUPERFAMILY SSF68912 37 77 2.55E-5 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 TIGRFAM TIGR00767 rho: transcription termination factor Rho 38 669 8.8E-200 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 Gene3D G3DSA:2.40.50.140 35 376 5.3E-44 T 28-03-2018 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 Pfam PF07497 Rho termination factor, RNA-binding domain 306 380 7.4E-30 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 411 615 1.1E-20 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 SMART SM00357 307 373 1.1E-11 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 SUPERFAMILY SSF50249 306 380 9.42E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS28815 61d47614bcaab88d4bd2d2b4784d31cd 680 SUPERFAMILY SSF52540 344 622 7.41E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS01365 924dd3a81c59b2e5aed416e53a387267 476 SUPERFAMILY SSF55874 343 459 7.34E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01365 924dd3a81c59b2e5aed416e53a387267 476 Pfam PF07730 Histidine kinase 239 302 1.0E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS01365 924dd3a81c59b2e5aed416e53a387267 476 Gene3D G3DSA:3.30.565.10 337 469 5.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26005 98b6a4604dda84018faa7cf842c95b53 394 SMART SM00327 218 377 2.4E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS26005 98b6a4604dda84018faa7cf842c95b53 394 SUPERFAMILY SSF53300 216 379 7.71E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS26005 98b6a4604dda84018faa7cf842c95b53 394 Gene3D G3DSA:3.40.50.410 176 368 8.2E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS26005 98b6a4604dda84018faa7cf842c95b53 394 Pfam PF05762 VWA domain containing CoxE-like protein 156 375 1.1E-59 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like SMD44_RS31400 fc1791cf352e5616e24e89c79bfd6103 541 Pfam PF00202 Aminotransferase class-III 39 382 1.8E-78 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS31400 fc1791cf352e5616e24e89c79bfd6103 541 SUPERFAMILY SSF53383 31 380 4.55E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS31400 fc1791cf352e5616e24e89c79bfd6103 541 SUPERFAMILY SSF53383 464 521 3.54E-9 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS31400 fc1791cf352e5616e24e89c79bfd6103 541 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 22 384 1.0E-129 T 28-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 SMD44_RS31400 fc1791cf352e5616e24e89c79bfd6103 541 Gene3D G3DSA:3.90.1150.10 324 534 2.1E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS31400 fc1791cf352e5616e24e89c79bfd6103 541 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 255 292 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS31400 fc1791cf352e5616e24e89c79bfd6103 541 Gene3D G3DSA:3.40.640.10 199 323 1.6E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS31400 fc1791cf352e5616e24e89c79bfd6103 541 Gene3D G3DSA:3.90.1150.10 19 179 1.1E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 SUPERFAMILY SSF101904 514 835 1.96E-98 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Gene3D G3DSA:1.10.268.10 360 502 2.2E-47 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 44 487 2.6E-149 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Gene3D G3DSA:3.90.199.10 46 228 1.8E-81 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 570 605 9.8E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 781 825 2.8E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 732 777 1.9E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 678 726 1.4E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 626 674 3.5E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 519 564 3.1E-14 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Gene3D G3DSA:3.30.1360.40 252 348 4.9E-31 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 SUPERFAMILY SSF56719 42 502 3.92E-169 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 4 829 23.034 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 SMART SM00434 23 480 1.3E-282 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 Gene3D G3DSA:2.120.10.90 511 829 5.2E-118 T 28-03-2018 SMD44_RS21155 f40aaa633b5c1aed04ca931abfbc4f8d 862 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 20 827 0.0 T 28-03-2018 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 Gene3D G3DSA:3.30.200.20 3 112 2.4E-12 T 28-03-2018 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 555 587 29.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 730 761 0.52 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 483 512 22.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 690 721 4.4E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 769 801 16.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 517 548 100.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 809 837 9.5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 644 675 50.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00564 600 630 4.8E-4 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 Gene3D G3DSA:2.140.10.10 405 591 7.7E-20 T 28-03-2018 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 Pfam PF00069 Protein kinase domain 16 261 2.3E-38 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 Pfam PF13570 PQQ-like domain 471 504 5.9E-4 T 28-03-2018 IPR025666 Pyrrolo-quinoline quinone-like domain SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SUPERFAMILY SSF50998 731 834 1.45E-20 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SUPERFAMILY SSF50998 515 764 1.37E-35 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SUPERFAMILY SSF56112 12 272 8.5E-62 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 Gene3D G3DSA:1.10.510.10 113 283 1.4E-41 T 28-03-2018 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 Pfam PF13360 PQQ-like domain 657 835 3.2E-24 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 SMART SM00220 16 271 1.8E-40 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 Gene3D G3DSA:2.140.10.10 592 724 3.8E-21 T 28-03-2018 SMD44_RS17930 5e86228c52fde784195fb0f1b637cfbc 839 Gene3D G3DSA:2.140.10.10 725 839 5.3E-22 T 28-03-2018 SMD44_RS09100 2558e25a07c4fad4c488d6baae10fb43 337 Pfam PF02616 Segregation and condensation protein ScpA 88 310 5.5E-51 T 28-03-2018 IPR003768 Segregation and condensation protein A SMD44_RS09100 2558e25a07c4fad4c488d6baae10fb43 337 Gene3D G3DSA:1.10.10.580 242 310 4.6E-11 T 28-03-2018 SMD44_RS29080 e024c5026fd949043b39d8491b35bf26 97 Pfam PF01910 Thiamine-binding protein 3 92 1.1E-30 T 28-03-2018 IPR002767 Thiamine-binding protein SMD44_RS29080 e024c5026fd949043b39d8491b35bf26 97 SUPERFAMILY SSF89957 1 95 2.09E-30 T 28-03-2018 IPR029756 MTH1187/YkoF-like SMD44_RS29080 e024c5026fd949043b39d8491b35bf26 97 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 2.2E-19 T 28-03-2018 IPR002767 Thiamine-binding protein SMD44_RS29080 e024c5026fd949043b39d8491b35bf26 97 Gene3D G3DSA:3.30.70.930 1 97 1.5E-34 T 28-03-2018 IPR029756 MTH1187/YkoF-like SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 Gene3D G3DSA:1.10.3860.10 17 422 8.3E-108 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 Pfam PF00375 Sodium:dicarboxylate symporter family 25 414 6.3E-110 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 PRINTS PR00173 Glutamate-aspartate symporter signature 65 85 2.5E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 PRINTS PR00173 Glutamate-aspartate symporter signature 19 39 2.5E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 PRINTS PR00173 Glutamate-aspartate symporter signature 95 120 2.5E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 2.5E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 PRINTS PR00173 Glutamate-aspartate symporter signature 369 389 2.5E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 PRINTS PR00173 Glutamate-aspartate symporter signature 343 362 2.5E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 PRINTS PR00173 Glutamate-aspartate symporter signature 308 334 2.5E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS24435 1cc78e6c269dcd977584b4cd35d9a25d 443 SUPERFAMILY SSF118215 25 414 2.62E-101 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS05060 2e52bc64442e8754bb2bf8ec56970e28 301 SUPERFAMILY SSF50129 1 117 1.67E-32 T 28-03-2018 IPR011032 GroES-like SMD44_RS05060 2e52bc64442e8754bb2bf8ec56970e28 301 SUPERFAMILY SSF50129 271 299 1.67E-32 T 28-03-2018 IPR011032 GroES-like SMD44_RS05060 2e52bc64442e8754bb2bf8ec56970e28 301 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 6.2E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS05060 2e52bc64442e8754bb2bf8ec56970e28 301 SMART SM00829 10 299 7.8E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS05060 2e52bc64442e8754bb2bf8ec56970e28 301 Pfam PF13602 Zinc-binding dehydrogenase 195 299 2.8E-15 T 28-03-2018 SMD44_RS05060 2e52bc64442e8754bb2bf8ec56970e28 301 SUPERFAMILY SSF51735 113 276 1.37E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS05060 2e52bc64442e8754bb2bf8ec56970e28 301 Gene3D G3DSA:3.90.180.10 1 301 3.3E-60 T 28-03-2018 SMD44_RS35995 30fe2ec10fda86d5c2bbe6b865f651de 190 SUPERFAMILY SSF55729 18 176 9.24E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS35995 30fe2ec10fda86d5c2bbe6b865f651de 190 Gene3D G3DSA:3.40.630.30 5 179 5.4E-29 T 28-03-2018 SMD44_RS35995 30fe2ec10fda86d5c2bbe6b865f651de 190 Pfam PF00583 Acetyltransferase (GNAT) family 61 144 5.2E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Gene3D G3DSA:3.90.480.10 491 642 2.8E-7 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PIRSF PIRSF037149 8 848 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 15 814 1.8E-302 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00397 Sirohaem Fe-binding site signature 649 667 8.4E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00397 Sirohaem Fe-binding site signature 692 710 8.4E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Pfam PF04324 BFD-like [2Fe-2S] binding domain 438 480 1.2E-6 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 2.0E-15 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 2.0E-15 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 2.0E-15 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.0E-15 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 SUPERFAMILY SSF56014 646 820 4.58E-50 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 SUPERFAMILY SSF51905 10 198 4.92E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Gene3D G3DSA:3.50.50.60 258 342 1.3E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 SUPERFAMILY SSF51905 158 320 7.21E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 573 634 8.7E-11 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 645 781 3.1E-18 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 692 708 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 182 3.3E-7 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 3.3E-7 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 3.3E-7 T 28-03-2018 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Gene3D G3DSA:3.50.50.60 2 112 3.5E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 SUPERFAMILY SSF55124 529 654 1.52E-22 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 303 5.8E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Gene3D G3DSA:3.50.50.60 113 253 1.4E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13420 9b0c72c3ef35e1cdeeb49947a9892564 861 Gene3D G3DSA:3.30.413.10 644 820 6.1E-37 T 28-03-2018 SMD44_RS26145 694b3b92aad4b9fa8db147e9596cf38e 83 Pfam PF01381 Helix-turn-helix 10 61 1.2E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS26145 694b3b92aad4b9fa8db147e9596cf38e 83 SUPERFAMILY SSF47413 3 68 8.31E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS26145 694b3b92aad4b9fa8db147e9596cf38e 83 SMART SM00530 8 63 4.1E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS26145 694b3b92aad4b9fa8db147e9596cf38e 83 Gene3D G3DSA:1.10.260.40 1 76 2.2E-16 T 28-03-2018 SMD44_RS09885 497815fefc8b92fdd5b078ec86c7ca1a 489 Pfam PF05787 Bacterial protein of unknown function (DUF839) 63 160 2.0E-15 T 28-03-2018 IPR008557 Protein of unknown function DUF839 SMD44_RS09885 497815fefc8b92fdd5b078ec86c7ca1a 489 Pfam PF05787 Bacterial protein of unknown function (DUF839) 164 475 1.5E-64 T 28-03-2018 IPR008557 Protein of unknown function DUF839 SMD44_RS09885 497815fefc8b92fdd5b078ec86c7ca1a 489 Gene3D G3DSA:2.140.10.30 318 476 9.3E-7 T 28-03-2018 SMD44_RS09885 497815fefc8b92fdd5b078ec86c7ca1a 489 SUPERFAMILY SSF63829 339 475 6.21E-11 T 28-03-2018 SMD44_RS09885 497815fefc8b92fdd5b078ec86c7ca1a 489 SUPERFAMILY SSF63829 205 279 6.21E-11 T 28-03-2018 SMD44_RS09885 497815fefc8b92fdd5b078ec86c7ca1a 489 Gene3D G3DSA:2.130.10.120 148 317 0.066 T 28-03-2018 SMD44_RS43310 757f61447b9f1ba77eee6d9f1850c424 263 ProDom PD038511 GENE GP88 GP85 PAE1962 44 146 1.0E-5 T 28-03-2018 IPR020290 Protein of unknown function, Gp85/88 SMD44_RS43310 757f61447b9f1ba77eee6d9f1850c424 263 Pfam PF17338 Gene 88 protein 21 253 1.1E-116 T 28-03-2018 IPR020290 Protein of unknown function, Gp85/88 SMD44_RS28780 5017414ff5ac0fa25f1c08754bef982d 161 Pfam PF00072 Response regulator receiver domain 27 137 1.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS28780 5017414ff5ac0fa25f1c08754bef982d 161 SUPERFAMILY SSF52172 26 148 2.28E-35 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS28780 5017414ff5ac0fa25f1c08754bef982d 161 SMART SM00448 25 137 1.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS28780 5017414ff5ac0fa25f1c08754bef982d 161 Gene3D G3DSA:3.40.50.2300 24 151 1.4E-34 T 28-03-2018 SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 SUPERFAMILY SSF52743 51 343 4.32E-79 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 Gene3D G3DSA:3.40.50.200 15 347 1.0E-82 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 74 85 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 127 137 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 60 411 4.8E-97 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 285 295 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 123 136 5.5E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 69 88 5.5E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 284 300 5.5E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS30955 46c72123d23c232c557ed2c89ad8619f 422 Pfam PF00082 Subtilase family 69 334 1.1E-50 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 Gene3D G3DSA:2.60.40.740 169 314 2.1E-17 T 28-03-2018 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 Gene3D G3DSA:2.60.40.10 31 168 8.6E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 Gene3D G3DSA:2.60.40.740 479 643 3.6E-8 T 28-03-2018 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 Gene3D G3DSA:2.60.40.740 661 860 1.1E-5 T 28-03-2018 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 179 228 2.2E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 690 720 1.1E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 325 365 7.2E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 Pfam PF01345 Domain of unknown function DUF11 323 426 2.9E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 Pfam PF01345 Domain of unknown function DUF11 177 240 1.1E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 SMD44_RS13095 d4d9de807aa5c9aeb89207840cab5d83 1018 Gene3D G3DSA:2.60.40.740 319 470 7.6E-11 T 28-03-2018 SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 Gene3D G3DSA:3.40.50.10730 174 299 7.8E-35 T 28-03-2018 SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 SUPERFAMILY SSF50129 310 360 1.55E-6 T 28-03-2018 IPR011032 GroES-like SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 SUPERFAMILY SSF51735 154 323 2.12E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 SUPERFAMILY SSF50129 4 186 1.24E-51 T 28-03-2018 IPR011032 GroES-like SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 Gene3D G3DSA:3.90.180.10 6 173 3.4E-44 T 28-03-2018 SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 SMART SM00829 14 361 3.2E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 6.2E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 Pfam PF00107 Zinc-binding dehydrogenase 190 316 3.5E-28 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS06770 90dba1777f3fd2074c0cc7058a21e2c7 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 361 2.1E-196 T 28-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 SUPERFAMILY SSF52821 151 278 9.95E-33 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 Gene3D G3DSA:3.40.250.10 1 143 3.1E-27 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 SUPERFAMILY SSF52821 4 131 5.76E-35 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 ProSitePatterns PS00683 Rhodanese C-terminal signature. 257 267 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 Gene3D G3DSA:3.40.250.10 158 281 1.9E-25 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 SMART SM00450 8 122 3.1E-19 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 SMART SM00450 146 273 9.2E-20 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 Pfam PF00581 Rhodanese-like domain 10 118 7.1E-17 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS19275 aacbdba224001021f2193dcef1cb986e 281 Pfam PF00581 Rhodanese-like domain 151 268 3.5E-15 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 170 3.3E-50 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 PIRSF PIRSF000109 1 479 7.8E-198 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 Gene3D G3DSA:1.10.1040.10 183 438 3.5E-102 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 5.5E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 252 279 5.5E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 5.5E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 170 198 5.5E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 5.5E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 5.5E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 SUPERFAMILY SSF48179 179 473 2.82E-115 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 256 268 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 181 470 1.0E-120 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 SMART SM01350 181 471 9.2E-196 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 Gene3D G3DSA:1.20.5.320 439 479 1.4E-17 T 28-03-2018 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 6 470 4.5E-200 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 Gene3D G3DSA:3.40.50.720 1 182 2.3E-40 T 28-03-2018 SMD44_RS37005 e811118a00434d9f58a651d59d09b378 479 SUPERFAMILY SSF51735 5 174 2.86E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31200 e991683fde59aec979b7b26193211064 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 5.7E-32 T 28-03-2018 IPR021408 Protein of unknown function DUF3046 SMD44_RS41940 fa3d59e98ffbd759cc119a2685afa4ca 203 Gene3D G3DSA:3.90.280.10 25 202 1.8E-33 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS41940 fa3d59e98ffbd759cc119a2685afa4ca 203 Pfam PF01161 Phosphatidylethanolamine-binding protein 73 201 2.6E-24 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS41940 fa3d59e98ffbd759cc119a2685afa4ca 203 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 71 200 1.2E-19 T 28-03-2018 IPR005247 YbhB/YbcL SMD44_RS41940 fa3d59e98ffbd759cc119a2685afa4ca 203 SUPERFAMILY SSF49777 44 191 1.83E-26 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS00150 ac86a43e83661dd5a6adc849cf84e47e 255 Pfam PF13401 AAA domain 42 153 3.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS00150 ac86a43e83661dd5a6adc849cf84e47e 255 Gene3D G3DSA:3.40.50.300 16 190 4.6E-11 T 28-03-2018 SMD44_RS00150 ac86a43e83661dd5a6adc849cf84e47e 255 SUPERFAMILY SSF52540 8 252 8.13E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 SUPERFAMILY SSF52317 1 189 4.01E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 Pfam PF01965 DJ-1/PfpI family 4 168 7.9E-16 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 Gene3D G3DSA:3.40.50.880 2 224 2.9E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 Gene3D G3DSA:1.10.10.60 225 264 6.6E-14 T 28-03-2018 SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 Pfam PF12833 Helix-turn-helix domain 229 307 3.4E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 260 302 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 SUPERFAMILY SSF46689 208 256 1.97E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 Gene3D G3DSA:1.10.10.60 265 313 1.5E-13 T 28-03-2018 SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 SUPERFAMILY SSF46689 260 310 1.01E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS41160 54a45557c18a2a8c7a8a51c238c4d4fb 319 SMART SM00342 223 306 4.5E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS03820 43e7e841edf7eb208bc362236fcf55aa 231 SUPERFAMILY SSF52317 2 230 3.67E-62 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS03820 43e7e841edf7eb208bc362236fcf55aa 231 Pfam PF01965 DJ-1/PfpI family 30 227 1.9E-14 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS03820 43e7e841edf7eb208bc362236fcf55aa 231 Gene3D G3DSA:3.40.50.880 1 230 1.9E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS35555 a4a926a5ec1e5f40bbdf84b3ee5f96e2 223 SMART SM00530 34 89 2.0E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS35555 a4a926a5ec1e5f40bbdf84b3ee5f96e2 223 Pfam PF07883 Cupin domain 130 198 6.0E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS35555 a4a926a5ec1e5f40bbdf84b3ee5f96e2 223 Gene3D G3DSA:1.10.260.40 30 93 1.1E-17 T 28-03-2018 SMD44_RS35555 a4a926a5ec1e5f40bbdf84b3ee5f96e2 223 SUPERFAMILY SSF47413 27 95 6.7E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS35555 a4a926a5ec1e5f40bbdf84b3ee5f96e2 223 Pfam PF13560 Helix-turn-helix domain 32 89 3.5E-16 T 28-03-2018 SMD44_RS35555 a4a926a5ec1e5f40bbdf84b3ee5f96e2 223 Gene3D G3DSA:2.60.120.10 94 208 3.7E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS35555 a4a926a5ec1e5f40bbdf84b3ee5f96e2 223 SUPERFAMILY SSF51182 95 200 3.82E-24 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS30605 c88df3e43d5eeb838f803a526ecd6e25 355 SUPERFAMILY SSF50331 253 354 5.16E-7 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMD44_RS30605 c88df3e43d5eeb838f803a526ecd6e25 355 SUPERFAMILY SSF52540 18 257 3.26E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30605 c88df3e43d5eeb838f803a526ecd6e25 355 Pfam PF00005 ABC transporter 34 176 1.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS30605 c88df3e43d5eeb838f803a526ecd6e25 355 SMART SM00382 43 226 2.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS30605 c88df3e43d5eeb838f803a526ecd6e25 355 Gene3D G3DSA:3.40.50.300 15 268 9.3E-69 T 28-03-2018 SMD44_RS30605 c88df3e43d5eeb838f803a526ecd6e25 355 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS30605 c88df3e43d5eeb838f803a526ecd6e25 355 Pfam PF08402 TOBE domain 284 354 2.2E-11 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMD44_RS12295 d3095e1d43ebe9ab07d902c7b4c30f30 589 Gene3D G3DSA:1.20.1250.20 15 203 2.7E-33 T 28-03-2018 SMD44_RS12295 d3095e1d43ebe9ab07d902c7b4c30f30 589 SUPERFAMILY SSF103473 19 202 1.44E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12295 d3095e1d43ebe9ab07d902c7b4c30f30 589 SUPERFAMILY SSF103473 253 470 1.44E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12295 d3095e1d43ebe9ab07d902c7b4c30f30 589 Gene3D G3DSA:1.20.1250.20 264 482 3.4E-29 T 28-03-2018 SMD44_RS12295 d3095e1d43ebe9ab07d902c7b4c30f30 589 Gene3D G3DSA:2.60.40.1120 501 587 3.1E-10 T 28-03-2018 SMD44_RS12295 d3095e1d43ebe9ab07d902c7b4c30f30 589 Pfam PF13620 Carboxypeptidase regulatory-like domain 503 579 1.9E-12 T 28-03-2018 SMD44_RS12295 d3095e1d43ebe9ab07d902c7b4c30f30 589 SUPERFAMILY SSF49464 503 582 6.28E-11 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMD44_RS12295 d3095e1d43ebe9ab07d902c7b4c30f30 589 Pfam PF07690 Major Facilitator Superfamily 24 418 5.8E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS01920 bbe69df5ec2a612954b6f976ada51fc8 344 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 254 343 9.0E-29 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01920 bbe69df5ec2a612954b6f976ada51fc8 344 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 129 216 9.1E-12 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01920 bbe69df5ec2a612954b6f976ada51fc8 344 Gene3D G3DSA:3.40.47.10 14 222 4.4E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01920 bbe69df5ec2a612954b6f976ada51fc8 344 SUPERFAMILY SSF53901 15 343 8.6E-50 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01920 bbe69df5ec2a612954b6f976ada51fc8 344 Gene3D G3DSA:3.40.47.10 223 344 9.0E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS24535 13f960601270e9e7f65e5034e282281d 557 Gene3D G3DSA:3.10.105.10 316 522 4.7E-38 T 28-03-2018 SMD44_RS24535 13f960601270e9e7f65e5034e282281d 557 PIRSF PIRSF002741 16 550 4.9E-64 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS24535 13f960601270e9e7f65e5034e282281d 557 Gene3D G3DSA:3.40.190.10 181 315 2.0E-29 T 28-03-2018 SMD44_RS24535 13f960601270e9e7f65e5034e282281d 557 SUPERFAMILY SSF53850 70 549 9.05E-93 T 28-03-2018 SMD44_RS24535 13f960601270e9e7f65e5034e282281d 557 Gene3D G3DSA:3.90.76.10 88 180 1.6E-22 T 28-03-2018 SMD44_RS24535 13f960601270e9e7f65e5034e282281d 557 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 107 476 1.8E-60 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS20430 5fe3f1a48b358162fff8b3d8409fddee 183 Pfam PF04542 Sigma-70 region 2 34 93 3.3E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20430 5fe3f1a48b358162fff8b3d8409fddee 183 Gene3D G3DSA:1.10.10.10 114 179 3.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20430 5fe3f1a48b358162fff8b3d8409fddee 183 SUPERFAMILY SSF88659 113 175 1.7E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20430 5fe3f1a48b358162fff8b3d8409fddee 183 Gene3D G3DSA:1.10.1740.10 10 96 5.3E-11 T 28-03-2018 SMD44_RS20430 5fe3f1a48b358162fff8b3d8409fddee 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 175 2.9E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20430 5fe3f1a48b358162fff8b3d8409fddee 183 Pfam PF08281 Sigma-70, region 4 121 173 4.7E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20430 5fe3f1a48b358162fff8b3d8409fddee 183 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 23 179 2.3E-63 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD44_RS20430 5fe3f1a48b358162fff8b3d8409fddee 183 SUPERFAMILY SSF88946 24 112 1.02E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18800 2c4c112a9077cfc9dea9cc77149c1e86 91 SUPERFAMILY SSF54285 1 91 2.8E-23 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMD44_RS18800 2c4c112a9077cfc9dea9cc77149c1e86 91 Gene3D G3DSA:3.10.20.30 1 91 5.1E-23 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS18800 2c4c112a9077cfc9dea9cc77149c1e86 91 Pfam PF02597 ThiS family 5 91 1.3E-17 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 SUPERFAMILY SSF54292 257 361 3.79E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 PRINTS PR00409 Phthalate dioxygenase reductase family signature 148 167 4.8E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 PRINTS PR00409 Phthalate dioxygenase reductase family signature 87 101 4.8E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 PRINTS PR00409 Phthalate dioxygenase reductase family signature 233 241 4.8E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 Gene3D G3DSA:2.40.30.10 43 132 1.4E-16 T 28-03-2018 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 Pfam PF00970 Oxidoreductase FAD-binding domain 67 137 4.0E-7 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 Gene3D G3DSA:3.40.50.80 137 262 2.1E-19 T 28-03-2018 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 Pfam PF00175 Oxidoreductase NAD-binding domain 149 213 3.5E-5 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 Gene3D G3DSA:3.10.20.30 263 361 2.2E-9 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 SUPERFAMILY SSF52343 137 265 6.55E-22 T 28-03-2018 SMD44_RS33690 982c4f5c555425b1e0f6eea236ece94d 362 SUPERFAMILY SSF63380 42 139 8.96E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS13495 ce7cee69a5f01aa2850024894c5d5ccc 383 PIRSF PIRSF006621 11 345 6.9E-102 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMD44_RS13495 ce7cee69a5f01aa2850024894c5d5ccc 383 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 14 330 1.1E-111 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 SMD44_RS13495 ce7cee69a5f01aa2850024894c5d5ccc 383 Gene3D G3DSA:3.20.20.70 18 257 8.8E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13495 ce7cee69a5f01aa2850024894c5d5ccc 383 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMD44_RS13495 ce7cee69a5f01aa2850024894c5d5ccc 383 Pfam PF01207 Dihydrouridine synthase (Dus) 24 326 1.2E-94 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMD44_RS13495 ce7cee69a5f01aa2850024894c5d5ccc 383 SUPERFAMILY SSF51395 21 331 8.79E-81 T 28-03-2018 SMD44_RS13495 ce7cee69a5f01aa2850024894c5d5ccc 383 Gene3D G3DSA:1.10.1200.80 267 344 2.1E-16 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 Hamap MF_00580 10 kDa chaperonin [groS]. 9 101 25.639 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 10 34 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 Gene3D G3DSA:2.30.33.40 4 101 2.6E-38 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 Pfam PF00166 Chaperonin 10 Kd subunit 10 100 1.2E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 PRINTS PR00297 10kDa chaperonin signature 10 25 2.8E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 PRINTS PR00297 10kDa chaperonin signature 87 100 2.8E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 PRINTS PR00297 10kDa chaperonin signature 32 53 2.8E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 PRINTS PR00297 10kDa chaperonin signature 66 78 2.8E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 SUPERFAMILY SSF50129 9 101 1.06E-32 T 28-03-2018 IPR011032 GroES-like SMD44_RS25770 30a71826c667c9cf96717b33698f479f 102 SMART SM00883 9 100 5.7E-52 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD44_RS02630 16e5262d681b36539a0c6b756609054b 255 Pfam PF12679 ABC-2 family transporter protein 62 255 2.6E-8 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS09705 85c8d5b6a99e2c07226e6939747352bb 134 SUPERFAMILY SSF51182 3 134 1.92E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS09705 85c8d5b6a99e2c07226e6939747352bb 134 Gene3D G3DSA:2.60.120.10 8 129 5.8E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS09705 85c8d5b6a99e2c07226e6939747352bb 134 Pfam PF06339 Ectoine synthase 2 127 3.1E-55 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS09705 85c8d5b6a99e2c07226e6939747352bb 134 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 38.222 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS09705 85c8d5b6a99e2c07226e6939747352bb 134 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 7.0E-60 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 Gene3D G3DSA:3.40.50.800 323 420 1.2E-18 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 417 30.981 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 PIRSF PIRSF001549 1 419 1.2E-103 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 Pfam PF03129 Anticodon binding domain 329 417 2.6E-13 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 Pfam PF13393 Histidyl-tRNA synthetase 9 309 1.4E-42 T 28-03-2018 SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 407 1.5E-132 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 Gene3D G3DSA:3.30.930.10 2 321 8.5E-65 T 28-03-2018 SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 SUPERFAMILY SSF52954 325 419 9.32E-23 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS07400 b3277015b5d28edec96304e7be70dfd5 420 SUPERFAMILY SSF55681 4 315 1.47E-82 T 28-03-2018 SMD44_RS13500 c56c1611c344a72c78630d251cb7fdee 274 Pfam PF13560 Helix-turn-helix domain 5 84 7.8E-15 T 28-03-2018 SMD44_RS13500 c56c1611c344a72c78630d251cb7fdee 274 SMART SM00530 9 81 0.001 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS13500 c56c1611c344a72c78630d251cb7fdee 274 SUPERFAMILY SSF47413 28 78 8.66E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS13500 c56c1611c344a72c78630d251cb7fdee 274 Gene3D G3DSA:1.10.260.40 1 81 5.3E-13 T 28-03-2018 SMD44_RS39725 149bf4d3285e8a5798dac62fa435f7cf 416 Gene3D G3DSA:2.60.40.10 318 414 3.3E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS39725 149bf4d3285e8a5798dac62fa435f7cf 416 SUPERFAMILY SSF49265 324 405 3.74E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS39725 149bf4d3285e8a5798dac62fa435f7cf 416 Pfam PF04389 Peptidase family M28 81 289 7.3E-28 T 28-03-2018 IPR007484 Peptidase M28 SMD44_RS39725 149bf4d3285e8a5798dac62fa435f7cf 416 Gene3D G3DSA:3.40.630.10 3 317 8.8E-47 T 28-03-2018 SMD44_RS39725 149bf4d3285e8a5798dac62fa435f7cf 416 SUPERFAMILY SSF53187 217 327 1.89E-49 T 28-03-2018 SMD44_RS39725 149bf4d3285e8a5798dac62fa435f7cf 416 SUPERFAMILY SSF53187 2 188 1.89E-49 T 28-03-2018 SMD44_RS04865 bffe706686df1b9ff661cb047a464268 242 Pfam PF01553 Acyltransferase 24 149 6.5E-30 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS04865 bffe706686df1b9ff661cb047a464268 242 Gene3D G3DSA:3.40.1130.10 1 214 6.0E-46 T 28-03-2018 SMD44_RS04865 bffe706686df1b9ff661cb047a464268 242 SUPERFAMILY SSF69593 20 204 6.02E-37 T 28-03-2018 SMD44_RS04865 bffe706686df1b9ff661cb047a464268 242 SMART SM00563 38 152 1.4E-36 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS14670 ed27f923299129b404e6d3d311715963 638 Gene3D G3DSA:2.30.38.10 428 500 2.6E-19 T 28-03-2018 SMD44_RS14670 ed27f923299129b404e6d3d311715963 638 ProSitePatterns PS00455 Putative AMP-binding domain signature. 214 225 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS14670 ed27f923299129b404e6d3d311715963 638 Gene3D G3DSA:3.40.50.980 44 219 1.5E-37 T 28-03-2018 SMD44_RS14670 ed27f923299129b404e6d3d311715963 638 Gene3D G3DSA:3.30.300.30 502 638 2.0E-17 T 28-03-2018 SMD44_RS14670 ed27f923299129b404e6d3d311715963 638 Gene3D G3DSA:3.40.50.980 220 427 1.9E-38 T 28-03-2018 SMD44_RS14670 ed27f923299129b404e6d3d311715963 638 SUPERFAMILY SSF56801 48 324 3.14E-114 T 28-03-2018 SMD44_RS14670 ed27f923299129b404e6d3d311715963 638 SUPERFAMILY SSF56801 378 638 3.14E-114 T 28-03-2018 SMD44_RS14670 ed27f923299129b404e6d3d311715963 638 Pfam PF00501 AMP-binding enzyme 56 507 4.3E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS21800 e0bf07053de2f70bf1a002e1a32a5144 533 Gene3D G3DSA:1.10.510.10 152 298 1.8E-40 T 28-03-2018 SMD44_RS21800 e0bf07053de2f70bf1a002e1a32a5144 533 SUPERFAMILY SSF56112 36 302 6.34E-72 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS21800 e0bf07053de2f70bf1a002e1a32a5144 533 Gene3D G3DSA:3.30.200.20 23 151 2.2E-28 T 28-03-2018 SMD44_RS21800 e0bf07053de2f70bf1a002e1a32a5144 533 SMART SM00220 38 300 1.3E-55 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS21800 e0bf07053de2f70bf1a002e1a32a5144 533 Pfam PF00069 Protein kinase domain 38 294 1.2E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS21800 e0bf07053de2f70bf1a002e1a32a5144 533 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 44 67 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 SMART SM00606 934 1060 6.6E-15 T 28-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Pfam PF06283 Trehalose utilisation 41 258 6.8E-75 T 28-03-2018 IPR029010 ThuA-like domain SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Gene3D G3DSA:3.40.50.880 34 272 1.5E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Pfam PF03422 Carbohydrate binding module (family 6) 939 1059 1.2E-19 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 SUPERFAMILY SSF49785 927 1058 3.4E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Gene3D G3DSA:2.60.40.10 1067 1154 5.1E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 SUPERFAMILY SSF52317 40 265 2.11E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Gene3D G3DSA:2.60.120.260 897 1066 1.5E-19 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Pfam PF07995 Glucose / Sorbosone dehydrogenase 285 544 5.3E-35 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Pfam PF00801 PKD domain 1073 1145 2.1E-13 T 28-03-2018 IPR000601 PKD domain SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Pfam PF00801 PKD domain 746 799 1.9E-11 T 28-03-2018 IPR000601 PKD domain SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 SUPERFAMILY SSF49299 1068 1153 9.55E-16 T 28-03-2018 IPR000601 PKD domain SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 SUPERFAMILY SSF49299 718 814 6.41E-18 T 28-03-2018 IPR000601 PKD domain SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Gene3D G3DSA:2.60.40.10 733 816 7.1E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 SUPERFAMILY SSF50952 275 547 1.1E-24 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 SMART SM00089 732 817 1.9E-20 T 28-03-2018 IPR022409 PKD/Chitinase domain SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 SMART SM00089 1070 1154 8.4E-18 T 28-03-2018 IPR022409 PKD/Chitinase domain SMD44_RS36005 c68a9024b11dd67d487cfd396cc6b5c4 1154 Gene3D G3DSA:2.120.10.30 273 728 7.9E-80 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS22215 22525fea9f499615e99ed523e991c6ae 110 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 8.7E-20 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD44_RS22215 22525fea9f499615e99ed523e991c6ae 110 Gene3D G3DSA:3.30.70.100 1 102 4.8E-22 T 28-03-2018 SMD44_RS22215 22525fea9f499615e99ed523e991c6ae 110 SUPERFAMILY SSF54909 1 93 5.37E-26 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 Gene3D G3DSA:3.90.640.10 190 245 1.7E-31 T 28-03-2018 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 SUPERFAMILY SSF53067 5 142 2.02E-42 T 28-03-2018 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 Pfam PF06723 MreB/Mbl protein 6 330 9.8E-156 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 Gene3D G3DSA:3.30.420.40 246 311 6.8E-12 T 28-03-2018 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 Gene3D G3DSA:3.30.420.40 3 153 2.1E-42 T 28-03-2018 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 Gene3D G3DSA:3.30.420.40 154 189 2.5E-4 T 28-03-2018 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 SUPERFAMILY SSF53067 144 322 1.73E-51 T 28-03-2018 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 4.4E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 4.4E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 4.4E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 4.4E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 4.4E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14065 e54ec395092a62c777e3e8b7f06be598 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 330 4.9E-153 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS15110 319b9060db3a9acce219fe5142c66463 363 Pfam PF14378 PAP2 superfamily 60 247 4.4E-61 T 28-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 Pfam PF12697 Alpha/beta hydrolase family 48 301 2.1E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 130 143 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 72 87 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00412 Epoxide hydrolase signature 252 268 2.5E-22 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00412 Epoxide hydrolase signature 116 129 2.5E-22 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00412 Epoxide hydrolase signature 286 308 2.5E-22 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00412 Epoxide hydrolase signature 130 143 2.5E-22 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00412 Epoxide hydrolase signature 52 70 2.5E-22 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 PRINTS PR00412 Epoxide hydrolase signature 72 87 2.5E-22 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 SUPERFAMILY SSF53474 23 311 5.4E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23210 3434346ba906243a94bc140960abb7f6 316 Gene3D G3DSA:3.40.50.1820 22 314 2.1E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS22865 fc209d3ef2c0066fb09917f7d8310406 613 Pfam PF00326 Prolyl oligopeptidase family 411 613 7.6E-40 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD44_RS22865 fc209d3ef2c0066fb09917f7d8310406 613 Gene3D G3DSA:3.40.50.1820 341 613 2.3E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS22865 fc209d3ef2c0066fb09917f7d8310406 613 SUPERFAMILY SSF82171 44 340 2.75E-25 T 28-03-2018 SMD44_RS22865 fc209d3ef2c0066fb09917f7d8310406 613 Gene3D G3DSA:2.140.10.30 181 340 1.8E-15 T 28-03-2018 SMD44_RS22865 fc209d3ef2c0066fb09917f7d8310406 613 Gene3D G3DSA:2.140.10.30 9 180 1.4E-13 T 28-03-2018 SMD44_RS22865 fc209d3ef2c0066fb09917f7d8310406 613 SUPERFAMILY SSF53474 362 613 1.96E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24750 86e1285eaa52eaeaedf1f218e0284c92 180 SUPERFAMILY SSF55729 16 164 7.88E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS24750 86e1285eaa52eaeaedf1f218e0284c92 180 Pfam PF13302 Acetyltransferase (GNAT) domain 21 159 6.2E-24 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS24750 86e1285eaa52eaeaedf1f218e0284c92 180 Gene3D G3DSA:3.40.630.30 7 180 1.6E-25 T 28-03-2018 SMD44_RS06260 64597b9757fe40fea02676ba60f7d97b 194 SUPERFAMILY SSF47413 9 75 4.29E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS06260 64597b9757fe40fea02676ba60f7d97b 194 Pfam PF07883 Cupin domain 114 182 1.3E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS06260 64597b9757fe40fea02676ba60f7d97b 194 Gene3D G3DSA:1.10.260.40 64 89 0.14 T 28-03-2018 SMD44_RS06260 64597b9757fe40fea02676ba60f7d97b 194 Gene3D G3DSA:1.10.260.40 1 63 5.5E-18 T 28-03-2018 SMD44_RS06260 64597b9757fe40fea02676ba60f7d97b 194 SUPERFAMILY SSF51182 62 185 4.02E-22 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS06260 64597b9757fe40fea02676ba60f7d97b 194 Pfam PF01381 Helix-turn-helix 15 68 6.3E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS06260 64597b9757fe40fea02676ba60f7d97b 194 SMART SM00530 14 69 2.6E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS06260 64597b9757fe40fea02676ba60f7d97b 194 Gene3D G3DSA:2.60.120.10 90 193 7.5E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS21040 cdc8a6b9aaab46efb3522c2d5188ae15 822 Gene3D G3DSA:2.60.40.10 629 729 7.7E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS21040 cdc8a6b9aaab46efb3522c2d5188ae15 822 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 117 - T 28-03-2018 IPR010916 TonB box, conserved site SMD44_RS21040 cdc8a6b9aaab46efb3522c2d5188ae15 822 Gene3D G3DSA:3.20.110.10 214 542 2.2E-4 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain SMD44_RS21040 cdc8a6b9aaab46efb3522c2d5188ae15 822 Gene3D G3DSA:2.60.40.10 95 213 4.5E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS31425 2978b08b416190c589523c26a772d898 261 SUPERFAMILY SSF46785 55 121 3.05E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31425 2978b08b416190c589523c26a772d898 261 Pfam PF01726 LexA DNA binding domain 54 117 1.1E-29 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 SMD44_RS31425 2978b08b416190c589523c26a772d898 261 Hamap MF_00015 LexA repressor [lexA]. 55 261 34.241 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 SMD44_RS31425 2978b08b416190c589523c26a772d898 261 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 216 228 2.5E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMD44_RS31425 2978b08b416190c589523c26a772d898 261 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 177 187 2.5E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMD44_RS31425 2978b08b416190c589523c26a772d898 261 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 188 199 2.5E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMD44_RS31425 2978b08b416190c589523c26a772d898 261 Pfam PF00717 Peptidase S24-like 180 244 9.3E-17 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS31425 2978b08b416190c589523c26a772d898 261 Gene3D G3DSA:1.10.10.10 55 120 2.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31425 2978b08b416190c589523c26a772d898 261 SUPERFAMILY SSF51306 141 259 9.94E-37 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS31425 2978b08b416190c589523c26a772d898 261 Gene3D G3DSA:2.10.109.10 146 261 5.3E-28 T 28-03-2018 SMD44_RS31425 2978b08b416190c589523c26a772d898 261 TIGRFAM TIGR00498 lexA: repressor LexA 54 261 8.4E-76 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 SMD44_RS28525 c934551f80b2e9d44922d84b2e09d576 319 Gene3D G3DSA:3.40.190.10 9 202 7.0E-37 T 28-03-2018 SMD44_RS28525 c934551f80b2e9d44922d84b2e09d576 319 SUPERFAMILY SSF53850 22 304 1.32E-57 T 28-03-2018 SMD44_RS28525 c934551f80b2e9d44922d84b2e09d576 319 Gene3D G3DSA:3.40.190.10 203 318 2.1E-15 T 28-03-2018 SMD44_RS28525 c934551f80b2e9d44922d84b2e09d576 319 SMART SM00062 68 307 3.3E-53 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS28525 c934551f80b2e9d44922d84b2e09d576 319 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 69 304 5.8E-64 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS23715 51fb82ce4da782d7944ebbbdfe3d93c3 198 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 119 130 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMD44_RS23715 51fb82ce4da782d7944ebbbdfe3d93c3 198 Gene3D G3DSA:3.30.70.560 29 188 1.2E-58 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMD44_RS23715 51fb82ce4da782d7944ebbbdfe3d93c3 198 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 34 164 3.8E-38 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMD44_RS23715 51fb82ce4da782d7944ebbbdfe3d93c3 198 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 33 164 2.3E-44 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMD44_RS23715 51fb82ce4da782d7944ebbbdfe3d93c3 198 SUPERFAMILY SSF55083 32 180 1.7E-49 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMD44_RS24325 8833b717eea8ba40444a3d80d14c1a1b 486 Gene3D G3DSA:3.50.50.60 1 200 1.3E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS24325 8833b717eea8ba40444a3d80d14c1a1b 486 SUPERFAMILY SSF51905 1 227 6.91E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS24325 8833b717eea8ba40444a3d80d14c1a1b 486 Pfam PF13454 FAD-NAD(P)-binding 4 156 3.3E-29 T 28-03-2018 SMD44_RS24325 8833b717eea8ba40444a3d80d14c1a1b 486 SUPERFAMILY SSF51905 342 405 1.6E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS24325 8833b717eea8ba40444a3d80d14c1a1b 486 SUPERFAMILY SSF51905 183 247 1.6E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS24325 8833b717eea8ba40444a3d80d14c1a1b 486 Gene3D G3DSA:3.50.50.60 201 485 2.4E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 Gene3D G3DSA:3.40.50.10260 1 228 8.2E-60 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 SUPERFAMILY SSF53613 240 495 2.5E-52 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 242 493 1.4E-43 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 237 498 19.686 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 SUPERFAMILY SSF64153 4 258 4.32E-47 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 223 20.682 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 Pfam PF01256 Carbohydrate kinase 260 480 6.6E-48 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 PIRSF PIRSF017184 1 496 3.1E-98 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 Pfam PF03853 YjeF-related protein N-terminus 25 202 1.4E-38 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD44_RS25700 1458b57f26770f454020919db8f971e1 498 Gene3D G3DSA:3.40.1190.20 233 498 8.7E-46 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 Gene3D G3DSA:3.40.50.300 1 236 2.5E-57 T 28-03-2018 SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 Gene3D G3DSA:3.40.50.300 292 530 2.7E-55 T 28-03-2018 SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 SUPERFAMILY SSF52540 292 512 6.51E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 SUPERFAMILY SSF52540 2 232 7.92E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 Pfam PF00005 ABC transporter 20 170 3.4E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 Pfam PF00005 ABC transporter 311 452 9.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 SMART SM00382 320 500 5.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS12440 277325950b378d0354d3372c7a465b1e 549 SMART SM00382 28 219 2.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS18200 be98ddce7f34d6bb7c4fa418d37dc120 404 Pfam PF12704 MacB-like periplasmic core domain 37 200 3.2E-16 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS18200 be98ddce7f34d6bb7c4fa418d37dc120 404 Pfam PF02687 FtsX-like permease family 309 397 8.1E-13 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS19865 45904481eaa0c667ee13fdca99286f1c 365 PIRSF PIRSF026760 11 355 2.6E-65 T 28-03-2018 IPR011669 Uncharacterised conserved protein UCP026760 SMD44_RS19865 45904481eaa0c667ee13fdca99286f1c 365 Pfam PF07755 Domain of unknown function (DUF1611_C) P-loop domain 161 339 2.0E-43 T 28-03-2018 IPR035086 Domain of unknown function DUF1611, P-loop SMD44_RS19865 45904481eaa0c667ee13fdca99286f1c 365 Gene3D G3DSA:3.40.50.720 8 155 2.2E-35 T 28-03-2018 SMD44_RS19865 45904481eaa0c667ee13fdca99286f1c 365 Gene3D G3DSA:3.40.50.300 160 333 1.9E-25 T 28-03-2018 SMD44_RS19865 45904481eaa0c667ee13fdca99286f1c 365 Pfam PF17396 Domain of unknown function (DUF1611_N) Rossmann-like domain 105 154 3.0E-8 T 28-03-2018 IPR035402 Domain of unknown function DUF1611_N, Rossmann-like domain SMD44_RS19865 45904481eaa0c667ee13fdca99286f1c 365 SUPERFAMILY SSF52540 6 351 5.31E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11805 7377dd4d11573e86eb4ec905176cff48 1045 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 144 465 1.7E-98 T 28-03-2018 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMD44_RS11805 7377dd4d11573e86eb4ec905176cff48 1045 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 50 130 9.7E-25 T 28-03-2018 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMD44_RS11805 7377dd4d11573e86eb4ec905176cff48 1045 Gene3D G3DSA:3.20.20.80 140 467 1.0E-101 T 28-03-2018 SMD44_RS11805 7377dd4d11573e86eb4ec905176cff48 1045 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 474 739 7.2E-72 T 28-03-2018 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMD44_RS11805 7377dd4d11573e86eb4ec905176cff48 1045 Gene3D G3DSA:1.20.120.670 468 753 9.2E-82 T 28-03-2018 SMD44_RS11805 7377dd4d11573e86eb4ec905176cff48 1045 Gene3D G3DSA:3.30.379.10 32 139 4.0E-33 T 28-03-2018 SMD44_RS11805 7377dd4d11573e86eb4ec905176cff48 1045 Gene3D G3DSA:2.60.120.200 848 1044 1.0E-19 T 28-03-2018 SMD44_RS38500 da7eefc2e59f4b9f54ef40ad886c7524 305 Gene3D G3DSA:3.40.50.1980 1 110 9.2E-21 T 28-03-2018 SMD44_RS38500 da7eefc2e59f4b9f54ef40ad886c7524 305 SUPERFAMILY SSF53807 71 288 3.92E-43 T 28-03-2018 SMD44_RS38500 da7eefc2e59f4b9f54ef40ad886c7524 305 SUPERFAMILY SSF53807 2 44 3.92E-43 T 28-03-2018 SMD44_RS38500 da7eefc2e59f4b9f54ef40ad886c7524 305 Gene3D G3DSA:3.40.50.1980 122 289 2.1E-35 T 28-03-2018 SMD44_RS38500 da7eefc2e59f4b9f54ef40ad886c7524 305 Pfam PF01497 Periplasmic binding protein 3 264 5.8E-13 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 Gene3D G3DSA:3.40.50.2300 64 190 2.2E-19 T 28-03-2018 SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 SMART SM00421 210 267 2.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 Pfam PF00196 Bacterial regulatory proteins, luxR family 213 265 2.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 Gene3D G3DSA:1.10.10.10 192 271 6.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 SMART SM00448 68 180 3.2E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 Pfam PF00072 Response regulator receiver domain 70 180 1.4E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 SUPERFAMILY SSF52172 66 235 2.16E-20 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 213 227 1.1E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 227 243 1.1E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01855 ec9cd21fcb357daa975c2de2e008bcec 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 243 255 1.1E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25170 2061a17cfb7fc8944bee84d4bfd9ac56 295 SUPERFAMILY SSF51679 1 264 1.57E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS25170 2061a17cfb7fc8944bee84d4bfd9ac56 295 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 22 270 1.5E-62 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMD44_RS25170 2061a17cfb7fc8944bee84d4bfd9ac56 295 Pfam PF00296 Luciferase-like monooxygenase 14 260 4.4E-46 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS25170 2061a17cfb7fc8944bee84d4bfd9ac56 295 Gene3D G3DSA:3.20.20.30 1 287 1.2E-60 T 28-03-2018 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 129 1.2E-30 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 SMART SM01232 147 239 3.5E-40 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 147 234 9.7E-21 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 SUPERFAMILY SSF46946 147 236 1.13E-25 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 Pfam PF06827 Zinc finger found in FPG and IleRS 261 287 9.1E-5 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 287 3.8E-83 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 ProSitePatterns PS01242 Zinc finger FPG-type signature. 263 287 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 Gene3D G3DSA:1.10.8.50 149 291 1.8E-45 T 28-03-2018 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 288 40.459 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 SUPERFAMILY SSF57716 239 288 3.14E-16 T 28-03-2018 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 SMART SM00898 2 131 9.7E-44 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 SUPERFAMILY SSF81624 2 152 7.72E-32 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS30365 06b2850058bbc63cd9db1e22397b0566 293 Gene3D G3DSA:3.20.190.10 2 139 5.4E-41 T 28-03-2018 SMD44_RS20470 2422929e6d7ff8b982a6fa1abe2e966c 366 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 42 270 2.1E-36 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS20470 2422929e6d7ff8b982a6fa1abe2e966c 366 SMART SM00942 303 365 5.0E-7 T 28-03-2018 IPR014820 Primase, C-terminal 1 SMD44_RS20470 2422929e6d7ff8b982a6fa1abe2e966c 366 SUPERFAMILY SSF56747 134 284 1.63E-29 T 28-03-2018 SMD44_RS20470 2422929e6d7ff8b982a6fa1abe2e966c 366 SMART SM00943 42 273 3.9E-31 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS39355 0bcf36f3061327a6998a1a9c53b2ff66 199 Gene3D G3DSA:3.40.50.150 1 191 1.6E-28 T 28-03-2018 SMD44_RS39355 0bcf36f3061327a6998a1a9c53b2ff66 199 Pfam PF08241 Methyltransferase domain 46 141 3.7E-18 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS39355 0bcf36f3061327a6998a1a9c53b2ff66 199 SUPERFAMILY SSF53335 8 186 2.13E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS12300 7fc12dc72889fb72341795660cf963ec 220 SUPERFAMILY SSF53335 39 192 2.93E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS12300 7fc12dc72889fb72341795660cf963ec 220 Pfam PF13578 Methyltransferase domain 43 171 1.0E-22 T 28-03-2018 SMD44_RS12300 7fc12dc72889fb72341795660cf963ec 220 Gene3D G3DSA:3.40.50.150 10 194 9.4E-23 T 28-03-2018 SMD44_RS39835 fdb7bd0837989141d6bcce3f99c7fcef 193 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 18 65 1.8E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS39835 fdb7bd0837989141d6bcce3f99c7fcef 193 Gene3D G3DSA:1.10.150.120 87 193 1.2E-35 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS39835 fdb7bd0837989141d6bcce3f99c7fcef 193 Pfam PF01799 [2Fe-2S] binding domain 85 174 6.5E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS39835 fdb7bd0837989141d6bcce3f99c7fcef 193 Gene3D G3DSA:3.10.20.30 10 86 3.0E-29 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS39835 fdb7bd0837989141d6bcce3f99c7fcef 193 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 51 59 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD44_RS39835 fdb7bd0837989141d6bcce3f99c7fcef 193 SUPERFAMILY SSF54292 13 100 1.31E-27 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS39835 fdb7bd0837989141d6bcce3f99c7fcef 193 SUPERFAMILY SSF47741 96 185 1.96E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS24710 0c4f6c70aec69857054e11b6a5bd9e7b 1015 Pfam PF03704 Bacterial transcriptional activator domain 859 974 2.4E-8 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS24710 0c4f6c70aec69857054e11b6a5bd9e7b 1015 SUPERFAMILY SSF48452 855 994 1.29E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS24710 0c4f6c70aec69857054e11b6a5bd9e7b 1015 Gene3D G3DSA:3.10.350.10 200 272 1.6E-9 T 28-03-2018 SMD44_RS24710 0c4f6c70aec69857054e11b6a5bd9e7b 1015 Gene3D G3DSA:1.25.40.10 856 1005 2.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS24710 0c4f6c70aec69857054e11b6a5bd9e7b 1015 SMART SM01043 858 1004 6.0E-8 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS10675 9db804803cec45edc5acbee47700f16f 302 SUPERFAMILY SSF53474 27 301 4.88E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS10675 9db804803cec45edc5acbee47700f16f 302 Gene3D G3DSA:3.40.50.1820 25 302 3.8E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS10675 9db804803cec45edc5acbee47700f16f 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 246 260 7.9E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS10675 9db804803cec45edc5acbee47700f16f 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 77 92 7.9E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS10675 9db804803cec45edc5acbee47700f16f 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 7.9E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS10675 9db804803cec45edc5acbee47700f16f 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 7.9E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS10675 9db804803cec45edc5acbee47700f16f 302 Pfam PF12697 Alpha/beta hydrolase family 51 292 2.1E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 PRINTS PR01806 Virulence factor MviN signature 24 43 3.2E-18 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 PRINTS PR01806 Virulence factor MviN signature 265 291 3.2E-18 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 PRINTS PR01806 Virulence factor MviN signature 43 59 3.2E-18 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 PRINTS PR01806 Virulence factor MviN signature 419 436 3.2E-18 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 PRINTS PR01806 Virulence factor MviN signature 123 147 3.2E-18 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 PRINTS PR01806 Virulence factor MviN signature 147 168 3.2E-18 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 PRINTS PR01806 Virulence factor MviN signature 363 382 3.2E-18 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 Pfam PF03023 MviN-like protein 20 474 2.8E-100 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS02775 ee5947e3889f2a4754731aa28d891419 522 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 1 517 4.6E-106 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS23645 0f06b472f3eda20e479f6e873787d65f 320 SUPERFAMILY SSF52540 5 225 1.33E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23645 0f06b472f3eda20e479f6e873787d65f 320 Gene3D G3DSA:3.40.50.300 1 315 2.5E-63 T 28-03-2018 SMD44_RS23645 0f06b472f3eda20e479f6e873787d65f 320 SMART SM00382 29 218 1.9E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS23645 0f06b472f3eda20e479f6e873787d65f 320 Pfam PF13732 Domain of unknown function (DUF4162) 217 306 3.4E-7 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 SMD44_RS23645 0f06b472f3eda20e479f6e873787d65f 320 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 308 2.3E-105 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD44_RS23645 0f06b472f3eda20e479f6e873787d65f 320 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS23645 0f06b472f3eda20e479f6e873787d65f 320 Pfam PF00005 ABC transporter 20 163 5.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS29765 a401ea22f4b7e3580e4b7dfa8af8b235 392 Gene3D G3DSA:3.40.640.10 10 263 6.7E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS29765 a401ea22f4b7e3580e4b7dfa8af8b235 392 PIRSF PIRSF005572 1 389 3.4E-106 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMD44_RS29765 a401ea22f4b7e3580e4b7dfa8af8b235 392 Gene3D G3DSA:3.90.1150.10 271 390 3.1E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS29765 a401ea22f4b7e3580e4b7dfa8af8b235 392 SUPERFAMILY SSF53383 2 384 1.2E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS29765 a401ea22f4b7e3580e4b7dfa8af8b235 392 Pfam PF00266 Aminotransferase class-V 3 375 3.0E-59 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 Pfam PF00364 Biotin-requiring enzyme 6 77 6.6E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 Gene3D G3DSA:3.30.559.10 320 563 1.2E-76 T 28-03-2018 SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 SUPERFAMILY SSF51230 3 86 4.45E-24 T 28-03-2018 IPR011053 Single hybrid motif SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 Pfam PF02817 e3 binding domain 232 266 1.2E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 Gene3D G3DSA:2.40.50.100 7 80 1.0E-14 T 28-03-2018 SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 SUPERFAMILY SSF47005 225 269 1.31E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 SUPERFAMILY SSF52777 329 560 8.01E-70 T 28-03-2018 SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 336 560 1.1E-70 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS21740 befefb9832e1fb4f4801ed4917c4c379 563 Gene3D G3DSA:4.10.320.10 189 273 3.6E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 Gene3D G3DSA:3.40.50.300 1 238 1.0E-65 T 28-03-2018 SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 Pfam PF03459 TOBE domain 306 367 1.2E-7 T 28-03-2018 IPR005116 Transport-associated OB, type 1 SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 SUPERFAMILY SSF52540 6 245 7.98E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 Gene3D G3DSA:2.40.50.100 242 286 2.0E-16 T 28-03-2018 SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 Pfam PF00005 ABC transporter 22 163 6.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 SUPERFAMILY SSF50331 238 376 3.68E-20 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 Gene3D G3DSA:2.40.50.140 303 358 1.9E-13 T 28-03-2018 SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS18965 4a4390b7f6cde50c7742f80d6a9b0243 378 SMART SM00382 30 213 3.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 Hamap MF_00347 Polyphosphate kinase [ppk]. 73 753 29.294 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 Pfam PF02503 Polyphosphate kinase middle domain 190 382 2.0E-62 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 Pfam PF13089 Polyphosphate kinase N-terminal domain 75 181 1.1E-36 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 74 748 4.1E-246 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 PIRSF PIRSF015589 58 759 5.0E-278 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 SUPERFAMILY SSF56024 570 751 3.59E-65 T 28-03-2018 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 SUPERFAMILY SSF140356 72 176 4.84E-36 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 SUPERFAMILY SSF143724 178 376 7.26E-61 T 28-03-2018 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 Gene3D G3DSA:3.30.870.10 384 569 2.4E-18 T 28-03-2018 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 Pfam PF13090 Polyphosphate kinase C-terminal domain 400 747 2.8E-152 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 Gene3D G3DSA:3.30.1840.10 180 370 1.7E-67 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 SUPERFAMILY SSF56024 402 567 9.42E-54 T 28-03-2018 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 Gene3D G3DSA:1.20.58.310 77 179 8.3E-37 T 28-03-2018 SMD44_RS19360 0fb4171a0bab22842194ff33e32ed122 760 Gene3D G3DSA:3.30.870.10 570 758 2.5E-40 T 28-03-2018 SMD44_RS37890 8874315c445705e8d635f74fbde4f8c5 139 Gene3D G3DSA:3.10.580.10 2 136 1.6E-27 T 28-03-2018 SMD44_RS37890 8874315c445705e8d635f74fbde4f8c5 139 SMART SM00116 77 124 1.5E-8 T 28-03-2018 IPR000644 CBS domain SMD44_RS37890 8874315c445705e8d635f74fbde4f8c5 139 SMART SM00116 12 59 3.0E-6 T 28-03-2018 IPR000644 CBS domain SMD44_RS37890 8874315c445705e8d635f74fbde4f8c5 139 SUPERFAMILY SSF54631 4 119 5.43E-29 T 28-03-2018 SMD44_RS37890 8874315c445705e8d635f74fbde4f8c5 139 Pfam PF00571 CBS domain 5 56 8.4E-10 T 28-03-2018 IPR000644 CBS domain SMD44_RS37890 8874315c445705e8d635f74fbde4f8c5 139 Pfam PF00571 CBS domain 73 120 5.3E-11 T 28-03-2018 IPR000644 CBS domain SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 SUPERFAMILY SSF46894 167 244 3.74E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 Pfam PF00196 Bacterial regulatory proteins, luxR family 183 238 3.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 ProSitePatterns PS00622 LuxR-type HTH domain signature. 198 225 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 Pfam PF00072 Response regulator receiver domain 33 144 1.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 SUPERFAMILY SSF52172 30 162 4.55E-36 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 Gene3D G3DSA:3.40.50.2300 30 155 3.6E-37 T 28-03-2018 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 SMART SM00448 31 144 5.4E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 198 7.8E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 214 7.8E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 214 226 7.8E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 SMART SM00421 181 238 3.2E-28 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16275 ec2acd5a19a1811f84c065002c2a0709 247 Gene3D G3DSA:1.10.10.10 156 247 1.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 SUPERFAMILY SSF46894 142 210 1.05E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 Gene3D G3DSA:3.40.50.2300 1 121 5.0E-34 T 28-03-2018 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 1.0E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 Gene3D G3DSA:1.10.10.10 122 213 5.0E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 Pfam PF00072 Response regulator receiver domain 2 110 8.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 SUPERFAMILY SSF52172 2 124 4.98E-30 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 SMART SM00448 1 110 1.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS33815 68465aebcbaa4cf367e5a7d8ddda223a 222 SMART SM00421 146 203 3.3E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11890 4a84fc1d281aa009a3755d0ef9fb8cad 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 129 283 1.2E-40 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD44_RS11890 4a84fc1d281aa009a3755d0ef9fb8cad 323 SUPERFAMILY SSF51735 107 283 2.66E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS11890 4a84fc1d281aa009a3755d0ef9fb8cad 323 Gene3D G3DSA:3.40.50.720 5 107 5.0E-12 T 28-03-2018 SMD44_RS11890 4a84fc1d281aa009a3755d0ef9fb8cad 323 Gene3D G3DSA:3.40.50.720 108 285 1.7E-43 T 28-03-2018 SMD44_RS11890 4a84fc1d281aa009a3755d0ef9fb8cad 323 SUPERFAMILY SSF52283 33 118 5.83E-8 T 28-03-2018 SMD44_RS34720 749035cd63b6a4cf1336c0c216d1fecb 347 Gene3D G3DSA:3.40.50.2300 51 175 4.5E-23 T 28-03-2018 SMD44_RS34720 749035cd63b6a4cf1336c0c216d1fecb 347 Gene3D G3DSA:3.40.50.2300 176 343 2.7E-24 T 28-03-2018 SMD44_RS34720 749035cd63b6a4cf1336c0c216d1fecb 347 SUPERFAMILY SSF53822 51 342 8.01E-64 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS34720 749035cd63b6a4cf1336c0c216d1fecb 347 Pfam PF13407 Periplasmic binding protein domain 55 312 2.4E-44 T 28-03-2018 IPR025997 Periplasmic binding protein SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 Pfam PF00574 Clp protease 21 200 4.5E-64 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 SUPERFAMILY SSF52096 17 203 4.4E-54 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 9 201 35.52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 PRINTS PR00127 Clp protease catalytic subunit P signature 96 113 1.1E-36 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 PRINTS PR00127 Clp protease catalytic subunit P signature 117 136 1.1E-36 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 PRINTS PR00127 Clp protease catalytic subunit P signature 65 85 1.1E-36 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 PRINTS PR00127 Clp protease catalytic subunit P signature 176 195 1.1E-36 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 PRINTS PR00127 Clp protease catalytic subunit P signature 25 40 1.1E-36 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 96 107 - T 28-03-2018 IPR018215 ClpP, Ser active site SMD44_RS05775 9982ebc392cb57f552a6e7dc737a83ff 209 Gene3D G3DSA:3.90.226.10 8 202 2.7E-33 T 28-03-2018 SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 Gene3D G3DSA:3.40.50.720 1 202 2.3E-52 T 28-03-2018 SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 Gene3D G3DSA:3.40.50.720 294 355 1.8E-14 T 28-03-2018 SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 SUPERFAMILY SSF55347 190 299 2.35E-35 T 28-03-2018 SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 300 6.0E-33 T 28-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 SUPERFAMILY SSF51735 3 185 8.31E-91 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 SUPERFAMILY SSF51735 297 356 8.31E-91 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 Gene3D G3DSA:3.30.360.10 203 293 1.3E-35 T 28-03-2018 SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 PIRSF PIRSF015578 1 359 4.1E-92 T 28-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD44_RS21020 1838171046a4831d056f24ffabd9ed67 360 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 354 3.4E-222 T 28-03-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria SMD44_RS33440 87d965ca8734e70383d5096c1461dc8e 277 Gene3D G3DSA:1.10.3100.10 15 158 2.7E-12 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS33440 87d965ca8734e70383d5096c1461dc8e 277 Pfam PF13560 Helix-turn-helix domain 19 73 1.7E-10 T 28-03-2018 SMD44_RS33440 87d965ca8734e70383d5096c1461dc8e 277 SUPERFAMILY SSF47413 18 68 1.15E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS33440 87d965ca8734e70383d5096c1461dc8e 277 SMART SM00530 23 78 1.4E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS08485 0d894ce9b9f21cb0451fe18fcda1111c 177 PIRSF PIRSF017340 3 176 3.0E-76 T 28-03-2018 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 SMD44_RS08485 0d894ce9b9f21cb0451fe18fcda1111c 177 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS08485 0d894ce9b9f21cb0451fe18fcda1111c 177 Pfam PF00293 NUDIX domain 38 150 3.0E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS08485 0d894ce9b9f21cb0451fe18fcda1111c 177 Gene3D G3DSA:3.90.79.10 4 177 8.7E-25 T 28-03-2018 SMD44_RS08485 0d894ce9b9f21cb0451fe18fcda1111c 177 SUPERFAMILY SSF55811 12 172 1.16E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS38725 ab34beee71d26ba7f989f4be9ef5a042 173 SMART SM00835 6 138 0.0054 T 28-03-2018 IPR006045 Cupin 1 GO:0045735 SMD44_RS38725 ab34beee71d26ba7f989f4be9ef5a042 173 SUPERFAMILY SSF51182 26 152 3.18E-27 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS38725 ab34beee71d26ba7f989f4be9ef5a042 173 Gene3D G3DSA:2.60.120.10 2 162 4.0E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS38725 ab34beee71d26ba7f989f4be9ef5a042 173 Pfam PF07883 Cupin domain 48 113 2.1E-17 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS36675 9e73e7ba2968e5d86d5ea8d482ae4d2b 173 SUPERFAMILY SSF160904 1 170 2.48E-37 T 28-03-2018 SMD44_RS36675 9e73e7ba2968e5d86d5ea8d482ae4d2b 173 Gene3D G3DSA:1.10.3300.10 5 173 2.2E-33 T 28-03-2018 IPR023286 ABATE domain SMD44_RS36675 9e73e7ba2968e5d86d5ea8d482ae4d2b 173 Pfam PF11706 CGNR zinc finger 129 170 5.7E-14 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS34695 5257b69ddcabda67084945c527d2edf8 315 Gene3D G3DSA:3.40.47.10 3 205 1.7E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS34695 5257b69ddcabda67084945c527d2edf8 315 Gene3D G3DSA:3.40.47.10 206 314 3.4E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS34695 5257b69ddcabda67084945c527d2edf8 315 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 225 313 9.0E-27 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS34695 5257b69ddcabda67084945c527d2edf8 315 SUPERFAMILY SSF53901 2 314 5.62E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS34695 5257b69ddcabda67084945c527d2edf8 315 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 313 2.5E-88 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS34695 5257b69ddcabda67084945c527d2edf8 315 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 179 6.6E-27 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS34695 5257b69ddcabda67084945c527d2edf8 315 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 314 59.295 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS30745 5db1233447f054b3d0d997fb9edb536b 394 Pfam PF00704 Glycosyl hydrolases family 18 64 378 1.8E-26 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMD44_RS30745 5db1233447f054b3d0d997fb9edb536b 394 ProSitePatterns PS01095 Chitinases family 18 active site. 174 182 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS30745 5db1233447f054b3d0d997fb9edb536b 394 SMART SM00636 62 378 1.2E-6 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SMD44_RS30745 5db1233447f054b3d0d997fb9edb536b 394 Gene3D G3DSA:3.20.20.80 56 394 1.7E-44 T 28-03-2018 SMD44_RS30745 5db1233447f054b3d0d997fb9edb536b 394 SUPERFAMILY SSF51445 63 386 3.99E-56 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 7.1E-38 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 Pfam PF02772 S-adenosylmethionine synthetase, central domain 111 233 9.7E-43 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 385 54.401 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 Gene3D G3DSA:3.30.300.10 138 261 3.6E-38 T 28-03-2018 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 PIRSF PIRSF000497 1 386 4.3E-157 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 SUPERFAMILY SSF55973 235 385 5.89E-66 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 374 1.2E-65 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 SUPERFAMILY SSF55973 106 233 1.06E-42 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 384 3.7E-161 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 111 121 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 Gene3D G3DSA:3.30.300.10 262 387 7.1E-47 T 28-03-2018 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 Gene3D G3DSA:3.30.300.10 13 111 1.5E-38 T 28-03-2018 SMD44_RS29390 b25fd69ac15157f2f75423abfdd96df8 387 SUPERFAMILY SSF55973 4 110 1.06E-42 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 204 3.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 SMART SM00448 5 129 2.4E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 Gene3D G3DSA:3.40.50.2300 4 140 1.3E-18 T 28-03-2018 SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 Gene3D G3DSA:1.10.10.10 141 223 1.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 Pfam PF00072 Response regulator receiver domain 7 117 2.6E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 SUPERFAMILY SSF52172 4 184 6.96E-15 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 SMART SM00421 157 219 8.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 2.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 2.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25245 1789bffc127dfa46bd442e1cffaa5b9f 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 2.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS43590 2abd5c662522696b091855f60abe16a3 305 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 4 286 18.34 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 SMD44_RS43590 2abd5c662522696b091855f60abe16a3 305 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 1 269 2.6E-105 T 28-03-2018 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 SMD44_RS43590 2abd5c662522696b091855f60abe16a3 305 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 132 237 5.0E-24 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 SMD44_RS43590 2abd5c662522696b091855f60abe16a3 305 Pfam PF01867 CRISPR associated protein Cas1 127 234 4.3E-11 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 Gene3D G3DSA:1.10.1660.10 1 54 2.0E-17 T 28-03-2018 SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.0E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.0E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.0E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 SMART SM00422 1 69 1.5E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 SUPERFAMILY SSF46955 2 111 1.17E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 Gene3D G3DSA:1.10.1660.10 55 122 6.5E-9 T 28-03-2018 SMD44_RS02235 dcbc9640f43caabfde1dafebe3757ca4 122 Pfam PF13411 MerR HTH family regulatory protein 2 67 1.6E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 SUPERFAMILY SSF88946 7 87 2.67E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 Pfam PF08281 Sigma-70, region 4 107 157 1.2E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 158 8.4E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 Gene3D G3DSA:1.10.1740.10 4 70 1.7E-13 T 28-03-2018 SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 Gene3D G3DSA:3.10.450.50 155 304 2.1E-18 T 28-03-2018 SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 6 292 1.5E-97 T 28-03-2018 IPR014303 RNA polymerase sigma-70, ECF type SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 Gene3D G3DSA:1.10.10.10 71 154 4.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 Pfam PF04542 Sigma-70 region 2 7 70 2.5E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 SUPERFAMILY SSF88659 80 158 2.8E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20360 b14612df796d13acacb8667aebc762a8 310 SUPERFAMILY SSF54427 168 292 4.75E-13 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS20160 e9a33122ccdf667e630563cdfc2e5614 339 Gene3D G3DSA:3.40.190.10 89 179 1.1E-23 T 28-03-2018 SMD44_RS20160 e9a33122ccdf667e630563cdfc2e5614 339 SUPERFAMILY SSF46785 1 112 2.14E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20160 e9a33122ccdf667e630563cdfc2e5614 339 SUPERFAMILY SSF53850 89 304 1.45E-39 T 28-03-2018 SMD44_RS20160 e9a33122ccdf667e630563cdfc2e5614 339 Gene3D G3DSA:1.10.10.10 1 84 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20160 e9a33122ccdf667e630563cdfc2e5614 339 Pfam PF03466 LysR substrate binding domain 89 301 3.9E-41 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS20160 e9a33122ccdf667e630563cdfc2e5614 339 Gene3D G3DSA:3.40.190.10 180 275 2.7E-23 T 28-03-2018 SMD44_RS20160 e9a33122ccdf667e630563cdfc2e5614 339 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 7.0E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS32645 80a39ddfb5e0cc2c8ba28b8046a7a96c 210 PIRSF PIRSF006324 1 210 4.3E-48 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMD44_RS32645 80a39ddfb5e0cc2c8ba28b8046a7a96c 210 Pfam PF01810 LysE type translocator 15 210 2.9E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMD44_RS36955 8fefee931d1b905853d17357141eb34d 530 Pfam PF03703 Bacterial PH domain 438 505 8.7E-9 T 28-03-2018 IPR005182 Domain of unknown function DUF304 SMD44_RS36955 8fefee931d1b905853d17357141eb34d 530 Pfam PF03703 Bacterial PH domain 81 163 1.3E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 SMD44_RS36955 8fefee931d1b905853d17357141eb34d 530 PIRSF PIRSF026631 19 508 4.1E-57 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 SMD44_RS37600 edb75826f3ceba7b84b467cb56f20257 216 Pfam PF00005 ABC transporter 25 152 6.9E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS37600 edb75826f3ceba7b84b467cb56f20257 216 Gene3D G3DSA:3.40.50.300 2 211 1.6E-51 T 28-03-2018 SMD44_RS37600 edb75826f3ceba7b84b467cb56f20257 216 SMART SM00382 33 206 4.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS37600 edb75826f3ceba7b84b467cb56f20257 216 SUPERFAMILY SSF52540 8 203 7.94E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21985 a1da2398ec68145e517c6f79ac2a428a 705 SUPERFAMILY SSF63829 426 525 3.92E-8 T 28-03-2018 SMD44_RS21985 a1da2398ec68145e517c6f79ac2a428a 705 SUPERFAMILY SSF63829 567 616 3.92E-8 T 28-03-2018 SMD44_RS21985 a1da2398ec68145e517c6f79ac2a428a 705 Gene3D G3DSA:2.120.10.30 177 690 6.9E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS21985 a1da2398ec68145e517c6f79ac2a428a 705 Pfam PF05787 Bacterial protein of unknown function (DUF839) 106 666 8.6E-168 T 28-03-2018 IPR008557 Protein of unknown function DUF839 SMD44_RS17235 e68d14d3a6736ffff7b06f637f561b96 351 SUPERFAMILY SSF63829 113 288 3.92E-9 T 28-03-2018 SMD44_RS17235 e68d14d3a6736ffff7b06f637f561b96 351 Gene3D G3DSA:2.120.10.30 51 342 1.3E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS14270 41be5eb6632366e352e6bbeb376c31a8 360 Gene3D G3DSA:3.40.960.10 200 354 4.5E-4 T 28-03-2018 SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 SUPERFAMILY SSF55658 1 56 1.31E-17 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 2.6E-21 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 9.0E-40 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 Gene3D G3DSA:3.10.430.100 63 147 8.1E-28 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 SUPERFAMILY SSF55653 59 147 8.76E-24 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 Gene3D G3DSA:3.40.5.10 1 49 3.5E-21 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.345 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS20970 f2870d63ba3e3d49f23f194122e12b24 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 1.2E-27 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 SUPERFAMILY SSF48452 499 619 7.59E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 SMART SM00220 11 279 6.0E-62 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Pfam PF13424 Tetratricopeptide repeat 549 616 7.8E-10 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Pfam PF13424 Tetratricopeptide repeat 680 749 3.9E-13 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Pfam PF13424 Tetratricopeptide repeat 428 496 4.7E-9 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Pfam PF00069 Protein kinase domain 11 268 4.4E-48 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Gene3D G3DSA:1.25.40.10 553 612 2.4E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 PIRSF PIRSF000615 94 222 2.1E-13 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Gene3D G3DSA:1.10.510.10 100 285 1.4E-51 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Gene3D G3DSA:3.30.200.20 2 99 1.0E-22 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Pfam PF13374 Tetratricopeptide repeat 383 421 6.9E-4 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Pfam PF13374 Tetratricopeptide repeat 506 547 5.1E-7 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Pfam PF13374 Tetratricopeptide repeat 632 673 2.8E-9 T 28-03-2018 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 SUPERFAMILY SSF48452 383 525 1.23E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 SUPERFAMILY SSF56112 8 301 1.34E-75 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 SUPERFAMILY SSF48452 627 748 1.22E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Gene3D G3DSA:1.10.10.10 613 689 1.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Gene3D G3DSA:1.10.10.10 392 479 2.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Gene3D G3DSA:1.10.10.10 480 552 5.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03510 cc04b9a3b3688a64ad9ab2a69803fd0c 755 Gene3D G3DSA:1.10.10.10 690 755 3.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11500 665c98e686a8fd7b2eaabbca2bf6494b 593 SUPERFAMILY SSF103473 214 251 9.02E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS11500 665c98e686a8fd7b2eaabbca2bf6494b 593 SUPERFAMILY SSF103473 28 183 9.02E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS11500 665c98e686a8fd7b2eaabbca2bf6494b 593 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 256 554 3.5E-109 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD44_RS11500 665c98e686a8fd7b2eaabbca2bf6494b 593 Gene3D G3DSA:3.40.630.30 359 504 6.3E-5 T 28-03-2018 SMD44_RS11500 665c98e686a8fd7b2eaabbca2bf6494b 593 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 31 233 1.2E-14 T 28-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 SMD44_RS01030 b486270629f2d44ccfcdb92a31a63d74 301 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 12 293 5.5E-121 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 SMD44_RS01030 b486270629f2d44ccfcdb92a31a63d74 301 Pfam PF13714 Phosphoenolpyruvate phosphomutase 19 255 1.6E-46 T 28-03-2018 SMD44_RS01030 b486270629f2d44ccfcdb92a31a63d74 301 SUPERFAMILY SSF51621 6 294 9.42E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS01030 b486270629f2d44ccfcdb92a31a63d74 301 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 9 295 46.62 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 SMD44_RS01030 b486270629f2d44ccfcdb92a31a63d74 301 Gene3D G3DSA:3.20.20.60 8 296 1.0E-85 T 28-03-2018 SMD44_RS01030 b486270629f2d44ccfcdb92a31a63d74 301 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 401 410 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00385 P450 superfamily signature 272 289 4.2E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00385 P450 superfamily signature 399 408 4.2E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00385 P450 superfamily signature 324 335 4.2E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00385 P450 superfamily signature 408 419 4.2E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 SUPERFAMILY SSF48264 17 459 1.57E-102 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 Pfam PF00067 Cytochrome P450 28 452 2.6E-73 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 Gene3D G3DSA:1.10.630.10 20 459 6.1E-117 T 28-03-2018 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00463 E-class P450 group I signature 49 68 5.1E-20 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00463 E-class P450 group I signature 281 307 5.1E-20 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00463 E-class P450 group I signature 363 387 5.1E-20 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00463 E-class P450 group I signature 408 431 5.1E-20 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00463 E-class P450 group I signature 261 278 5.1E-20 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28300 a5793d52134e67a271c77e53c79f97e8 459 PRINTS PR00463 E-class P450 group I signature 398 408 5.1E-20 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS08535 03489cc8b9ce2a651e7fb5d4c6e20202 339 Gene3D G3DSA:1.10.10.10 11 103 1.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08535 03489cc8b9ce2a651e7fb5d4c6e20202 339 Gene3D G3DSA:3.40.190.10 104 241 2.1E-6 T 28-03-2018 SMD44_RS08535 03489cc8b9ce2a651e7fb5d4c6e20202 339 SUPERFAMILY SSF46785 17 112 2.88E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08535 03489cc8b9ce2a651e7fb5d4c6e20202 339 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 83 8.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS08535 03489cc8b9ce2a651e7fb5d4c6e20202 339 SUPERFAMILY SSF53850 120 312 8.58E-7 T 28-03-2018 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 254 267 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 13 585 3.4E-216 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 SUPERFAMILY SSF51569 31 341 2.56E-87 T 28-03-2018 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 Gene3D G3DSA:3.20.20.70 18 397 1.1E-99 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 SMART SM00917 443 586 6.9E-23 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 Pfam PF08502 LeuA allosteric (dimerisation) domain 445 585 2.4E-22 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 13 587 50.904 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 SUPERFAMILY SSF110921 470 584 4.97E-29 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 SUPERFAMILY SSF89000 410 458 4.32E-11 T 28-03-2018 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 48 64 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS29605 6078ddba06f54afdc10ffe1807c15418 589 Pfam PF00682 HMGL-like 43 324 2.0E-64 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMD44_RS22745 130ec0343b9b53a56f886698d1ae99ad 251 SUPERFAMILY SSF48008 84 225 2.62E-10 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS22745 130ec0343b9b53a56f886698d1ae99ad 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 3.5E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS22745 130ec0343b9b53a56f886698d1ae99ad 251 SMART SM00345 18 76 6.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS22745 130ec0343b9b53a56f886698d1ae99ad 251 Pfam PF07729 FCD domain 88 216 1.2E-6 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS22745 130ec0343b9b53a56f886698d1ae99ad 251 SUPERFAMILY SSF46785 12 80 2.48E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22745 130ec0343b9b53a56f886698d1ae99ad 251 Gene3D G3DSA:1.10.10.10 8 79 3.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22745 130ec0343b9b53a56f886698d1ae99ad 251 Gene3D G3DSA:1.20.120.530 80 238 2.4E-40 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS17685 16019a704ef4b60310caa6ccd96b3ede 196 Gene3D G3DSA:1.10.260.40 22 124 6.1E-15 T 28-03-2018 SMD44_RS17685 16019a704ef4b60310caa6ccd96b3ede 196 SMART SM00530 35 106 6.2E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS17685 16019a704ef4b60310caa6ccd96b3ede 196 Pfam PF13560 Helix-turn-helix domain 31 109 1.4E-15 T 28-03-2018 SMD44_RS17685 16019a704ef4b60310caa6ccd96b3ede 196 SUPERFAMILY SSF47413 55 102 1.91E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS31345 80e1ec1d687911b1d6befde4aa887d88 244 SUPERFAMILY SSF53213 112 244 4.45E-5 T 28-03-2018 SMD44_RS31345 80e1ec1d687911b1d6befde4aa887d88 244 Gene3D G3DSA:3.40.830.10 1 244 1.1E-39 T 28-03-2018 SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 SMART SM00740 622 686 1.3E-14 T 28-03-2018 IPR005543 PASTA domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 SMART SM00740 555 621 2.4E-17 T 28-03-2018 IPR005543 PASTA domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 SMART SM00740 419 486 1.9E-14 T 28-03-2018 IPR005543 PASTA domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 SMART SM00740 487 554 1.0E-13 T 28-03-2018 IPR005543 PASTA domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 SMART SM00220 18 280 4.7E-52 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 SUPERFAMILY SSF54184 626 685 9.68E-6 T 28-03-2018 SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 Pfam PF00069 Protein kinase domain 19 262 7.4E-47 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 Gene3D G3DSA:3.30.200.20 16 84 6.2E-17 T 28-03-2018 SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 Pfam PF03793 PASTA domain 491 554 4.8E-13 T 28-03-2018 IPR005543 PASTA domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 Pfam PF03793 PASTA domain 558 621 1.3E-15 T 28-03-2018 IPR005543 PASTA domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 Pfam PF03793 PASTA domain 424 485 8.4E-11 T 28-03-2018 IPR005543 PASTA domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 Pfam PF03793 PASTA domain 626 685 1.5E-11 T 28-03-2018 IPR005543 PASTA domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 SUPERFAMILY SSF56112 15 280 2.8E-73 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS11175 f9979d547f9b0f2b467c2f1f4a5ca04e 686 Gene3D G3DSA:1.10.510.10 85 351 5.1E-52 T 28-03-2018 SMD44_RS05055 204a8ab030e5dfb7a666c82f074db05e 212 Pfam PF02600 Disulfide bond formation protein DsbB 24 115 2.1E-10 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 SMD44_RS05055 204a8ab030e5dfb7a666c82f074db05e 212 Gene3D G3DSA:1.20.1550.10 18 190 3.0E-28 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain SMD44_RS05055 204a8ab030e5dfb7a666c82f074db05e 212 SUPERFAMILY SSF158442 27 144 2.22E-17 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain SMD44_RS25855 7179dd41cabfd4562154e861702ecdea 624 Gene3D G3DSA:1.10.510.10 101 276 4.7E-42 T 28-03-2018 SMD44_RS25855 7179dd41cabfd4562154e861702ecdea 624 Gene3D G3DSA:3.40.1000.10 490 622 6.6E-13 T 28-03-2018 SMD44_RS25855 7179dd41cabfd4562154e861702ecdea 624 Pfam PF00069 Protein kinase domain 15 263 5.9E-46 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25855 7179dd41cabfd4562154e861702ecdea 624 Gene3D G3DSA:3.30.200.20 3 100 1.6E-22 T 28-03-2018 SMD44_RS25855 7179dd41cabfd4562154e861702ecdea 624 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS25855 7179dd41cabfd4562154e861702ecdea 624 SUPERFAMILY SSF56112 11 272 4.45E-65 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS25855 7179dd41cabfd4562154e861702ecdea 624 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS25855 7179dd41cabfd4562154e861702ecdea 624 SMART SM00220 15 274 9.1E-61 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS10250 bf9ed9f36d9162e32e507f2ae2ff93b7 296 Pfam PF03707 Bacterial signalling protein N terminal repeat 120 170 2.7E-16 T 28-03-2018 IPR005330 MHYT domain SMD44_RS10250 bf9ed9f36d9162e32e507f2ae2ff93b7 296 Pfam PF03707 Bacterial signalling protein N terminal repeat 56 112 1.2E-13 T 28-03-2018 IPR005330 MHYT domain SMD44_RS10250 bf9ed9f36d9162e32e507f2ae2ff93b7 296 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 228 8.9E-6 T 28-03-2018 IPR005330 MHYT domain SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 Pfam PF00005 ABC transporter 356 502 3.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 16 544 2.3E-189 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 SMART SM00382 362 555 1.3E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 Pfam PF00664 ABC transporter transmembrane region 20 279 6.9E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 SUPERFAMILY SSF52540 328 549 1.68E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 SUPERFAMILY SSF90123 1 319 2.22E-53 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 Gene3D G3DSA:1.20.1560.10 5 321 5.2E-44 T 28-03-2018 SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 Gene3D G3DSA:3.40.50.300 322 558 6.2E-63 T 28-03-2018 SMD44_RS38565 878292ffe03d66cf7fb1c3e8e32b3d21 573 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS04930 ae4a39cca2a7462540be9053352e4713 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 113 4.0E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS04930 ae4a39cca2a7462540be9053352e4713 128 SUPERFAMILY SSF54593 11 121 1.34E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS04930 ae4a39cca2a7462540be9053352e4713 128 Gene3D G3DSA:3.10.180.10 7 126 3.3E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS08085 512a11cae21d7df37bf6eda344a50279 300 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 241 16.636 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD44_RS08085 512a11cae21d7df37bf6eda344a50279 300 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 3 227 2.2E-55 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD44_RS08085 512a11cae21d7df37bf6eda344a50279 300 Pfam PF00902 Sec-independent protein translocase protein (TatC) 5 222 1.0E-60 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD44_RS08085 512a11cae21d7df37bf6eda344a50279 300 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 104 130 2.2E-33 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD44_RS08085 512a11cae21d7df37bf6eda344a50279 300 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 86 104 2.2E-33 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD44_RS08085 512a11cae21d7df37bf6eda344a50279 300 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 2.2E-33 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD44_RS08085 512a11cae21d7df37bf6eda344a50279 300 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 2.2E-33 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD44_RS37480 28ed7e507219f94fa007691190b9b0f4 454 Gene3D G3DSA:3.90.1580.10 185 453 3.2E-69 T 28-03-2018 SMD44_RS37480 28ed7e507219f94fa007691190b9b0f4 454 Gene3D G3DSA:1.20.120.450 2 184 1.8E-17 T 28-03-2018 SMD44_RS37480 28ed7e507219f94fa007691190b9b0f4 454 Pfam PF03781 Sulfatase-modifying factor enzyme 1 184 442 1.3E-63 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMD44_RS37480 28ed7e507219f94fa007691190b9b0f4 454 SUPERFAMILY SSF109854 13 153 2.33E-19 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS37480 28ed7e507219f94fa007691190b9b0f4 454 SUPERFAMILY SSF56436 183 444 1.75E-76 T 28-03-2018 IPR016187 C-type lectin fold SMD44_RS37480 28ed7e507219f94fa007691190b9b0f4 454 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 444 51.886 T 28-03-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 SMD44_RS37480 28ed7e507219f94fa007691190b9b0f4 454 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 25 441 5.9E-137 T 28-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 SMD44_RS37480 28ed7e507219f94fa007691190b9b0f4 454 Pfam PF12867 DinB superfamily 27 157 2.5E-27 T 28-03-2018 IPR024775 DinB-like domain SMD44_RS32155 79c85ea649b92c753cf79817e599b14b 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 274 2.9E-51 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS32155 79c85ea649b92c753cf79817e599b14b 275 SUPERFAMILY SSF52096 11 275 2.49E-77 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS32155 79c85ea649b92c753cf79817e599b14b 275 Gene3D G3DSA:1.10.12.10 233 275 3.5E-13 T 28-03-2018 IPR014748 Crontonase, C-terminal SMD44_RS32155 79c85ea649b92c753cf79817e599b14b 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD44_RS32155 79c85ea649b92c753cf79817e599b14b 275 Gene3D G3DSA:3.90.226.10 16 232 5.3E-60 T 28-03-2018 SMD44_RS16245 4395f33e42b251c4d92ec76c0e0140f6 222 Pfam PF12710 haloacid dehalogenase-like hydrolase 10 175 9.0E-11 T 28-03-2018 SMD44_RS16245 4395f33e42b251c4d92ec76c0e0140f6 222 SUPERFAMILY SSF56784 9 215 4.43E-28 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS16245 4395f33e42b251c4d92ec76c0e0140f6 222 Gene3D G3DSA:3.40.50.1000 70 222 3.4E-15 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS26405 d9daca1af14bed1c8f489edf679f4129 431 PIRSF PIRSF000412 2 430 3.1E-164 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD44_RS26405 d9daca1af14bed1c8f489edf679f4129 431 Pfam PF00464 Serine hydroxymethyltransferase 19 394 1.4E-152 T 28-03-2018 SMD44_RS26405 d9daca1af14bed1c8f489edf679f4129 431 Gene3D G3DSA:3.90.1150.10 283 426 1.6E-57 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS26405 d9daca1af14bed1c8f489edf679f4129 431 Gene3D G3DSA:3.40.640.10 47 282 9.8E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS26405 d9daca1af14bed1c8f489edf679f4129 431 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 17 427 48.775 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD44_RS26405 d9daca1af14bed1c8f489edf679f4129 431 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 232 248 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD44_RS26405 d9daca1af14bed1c8f489edf679f4129 431 SUPERFAMILY SSF53383 17 427 2.42E-161 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 Pfam PF00994 Probable molybdopterin binding domain 122 268 1.5E-21 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 Gene3D G3DSA:3.40.980.10 104 275 1.7E-39 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 Gene3D G3DSA:3.90.105.10 71 103 7.7E-12 T 28-03-2018 SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 Pfam PF03454 MoeA C-terminal region (domain IV) 281 343 3.4E-8 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 SUPERFAMILY SSF63882 1 116 6.02E-25 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 Pfam PF03453 MoeA N-terminal region (domain I and II) 1 108 2.4E-22 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 Gene3D G3DSA:2.40.340.10 278 345 7.4E-7 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 SMART SM00852 121 269 2.5E-24 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 SUPERFAMILY SSF63867 278 344 2.29E-7 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 Gene3D G3DSA:2.170.190.11 1 70 3.1E-20 T 28-03-2018 SMD44_RS21750 a0beaddf686eb2705b5656574a764636 369 SUPERFAMILY SSF53218 117 279 1.28E-26 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS05360 eb17b71b1cc7183abe7e94415a9c3f48 217 Pfam PF01965 DJ-1/PfpI family 3 183 2.2E-12 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS05360 eb17b71b1cc7183abe7e94415a9c3f48 217 SUPERFAMILY SSF52317 1 186 3.36E-28 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS05360 eb17b71b1cc7183abe7e94415a9c3f48 217 Gene3D G3DSA:3.40.50.880 1 209 2.1E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS22055 6db2cb2bb5b61039db8344eaa348418f 430 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 225 420 6.9E-24 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS22055 6db2cb2bb5b61039db8344eaa348418f 430 SUPERFAMILY SSF52266 221 425 3.51E-41 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS22055 6db2cb2bb5b61039db8344eaa348418f 430 Gene3D G3DSA:3.40.50.1110 211 426 5.0E-28 T 28-03-2018 SMD44_RS18100 bd3920fd19ee509de7463a2028481868 517 SUPERFAMILY SSF56801 13 517 8.63E-113 T 28-03-2018 SMD44_RS18100 bd3920fd19ee509de7463a2028481868 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 501 9.1E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS18100 bd3920fd19ee509de7463a2028481868 517 Gene3D G3DSA:3.30.300.30 412 516 4.1E-22 T 28-03-2018 SMD44_RS18100 bd3920fd19ee509de7463a2028481868 517 Gene3D G3DSA:2.30.38.10 339 411 2.7E-20 T 28-03-2018 SMD44_RS18100 bd3920fd19ee509de7463a2028481868 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS18100 bd3920fd19ee509de7463a2028481868 517 Gene3D G3DSA:3.40.50.980 11 174 5.5E-28 T 28-03-2018 SMD44_RS18100 bd3920fd19ee509de7463a2028481868 517 Gene3D G3DSA:3.40.50.980 175 328 8.5E-30 T 28-03-2018 SMD44_RS18100 bd3920fd19ee509de7463a2028481868 517 Pfam PF00501 AMP-binding enzyme 20 418 1.2E-67 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS26900 76db0b89fe8223085dbfd5ee0d9ee184 327 Gene3D G3DSA:3.20.20.70 45 327 1.6E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS26900 76db0b89fe8223085dbfd5ee0d9ee184 327 SUPERFAMILY SSF51569 69 307 8.48E-73 T 28-03-2018 SMD44_RS26900 76db0b89fe8223085dbfd5ee0d9ee184 327 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 71 289 1.1E-54 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMD44_RS26900 76db0b89fe8223085dbfd5ee0d9ee184 327 SMART SM01133 68 308 7.4E-72 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMD44_RS26900 76db0b89fe8223085dbfd5ee0d9ee184 327 PIRSF PIRSF001357 62 317 4.7E-84 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMD44_RS26900 76db0b89fe8223085dbfd5ee0d9ee184 327 Pfam PF01791 DeoC/LacD family aldolase 65 306 2.7E-27 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMD44_RS05480 38c7d6cd8ebaf8b9df283ee47140f07a 201 Gene3D G3DSA:2.30.320.10 1 196 3.2E-18 T 28-03-2018 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 SUPERFAMILY SSF52540 6 221 1.15E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 SUPERFAMILY SSF50465 305 397 1.96E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 Gene3D G3DSA:3.40.50.300 77 205 4.1E-32 T 28-03-2018 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 Gene3D G3DSA:2.40.30.10 303 396 1.9E-33 T 28-03-2018 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 4.6E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 Gene3D G3DSA:3.40.50.300 2 76 2.0E-11 T 28-03-2018 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 1.7E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.431 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 396 1.8E-222 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 Gene3D G3DSA:2.40.30.10 208 299 2.1E-30 T 28-03-2018 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 SUPERFAMILY SSF50447 207 304 4.91E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 9.2E-59 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25490 8270343ad4698ab26cdf2bc14bab0cbf 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 4.9E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SMD44_RS24355 b163559d52e0d22e9710eae5085dc658 428 SUPERFAMILY SSF88713 154 381 4.73E-28 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS24355 b163559d52e0d22e9710eae5085dc658 428 SUPERFAMILY SSF88713 74 124 4.73E-28 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS24355 b163559d52e0d22e9710eae5085dc658 428 Gene3D G3DSA:3.20.20.370 66 391 3.7E-38 T 28-03-2018 SMD44_RS13065 fac064d2f2e47debcb8116bd3164e268 336 SUPERFAMILY SSF54211 19 149 8.35E-16 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS13065 fac064d2f2e47debcb8116bd3164e268 336 Pfam PF00288 GHMP kinases N terminal domain 74 123 8.2E-9 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMD44_RS13065 fac064d2f2e47debcb8116bd3164e268 336 Gene3D G3DSA:3.30.230.10 20 129 6.7E-15 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS13065 fac064d2f2e47debcb8116bd3164e268 336 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 80 91 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SMD44_RS01775 9df9b51840f0397e156bd30b1a23c001 320 SUPERFAMILY SSF75005 27 314 1.45E-60 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMD44_RS01775 9df9b51840f0397e156bd30b1a23c001 320 Pfam PF04616 Glycosyl hydrolases family 43 31 307 1.0E-40 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 SMD44_RS01775 9df9b51840f0397e156bd30b1a23c001 320 Gene3D G3DSA:2.115.10.20 21 320 1.2E-58 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMD44_RS00145 c1eec0e8be3b2600fa5b6fadd8e1fa9d 234 Gene3D G3DSA:3.30.200.20 5 73 7.6E-7 T 28-03-2018 SMD44_RS00145 c1eec0e8be3b2600fa5b6fadd8e1fa9d 234 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 124 136 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS00145 c1eec0e8be3b2600fa5b6fadd8e1fa9d 234 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS00145 c1eec0e8be3b2600fa5b6fadd8e1fa9d 234 Gene3D G3DSA:1.10.510.10 74 230 2.9E-42 T 28-03-2018 SMD44_RS00145 c1eec0e8be3b2600fa5b6fadd8e1fa9d 234 Pfam PF00069 Protein kinase domain 19 215 1.5E-35 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS00145 c1eec0e8be3b2600fa5b6fadd8e1fa9d 234 SUPERFAMILY SSF56112 9 220 1.27E-51 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS00145 c1eec0e8be3b2600fa5b6fadd8e1fa9d 234 SMART SM00220 15 232 5.2E-28 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS35330 f38e4cc107d0d0299720c63dc343218d 394 Pfam PF02515 CoA-transferase family III 12 361 8.7E-88 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMD44_RS35330 f38e4cc107d0d0299720c63dc343218d 394 SUPERFAMILY SSF89796 10 369 1.44E-115 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS35330 f38e4cc107d0d0299720c63dc343218d 394 Gene3D G3DSA:3.40.50.10540 7 373 1.3E-118 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS08625 9a8767fb32d14810645f1bea4321d922 219 Gene3D G3DSA:1.10.357.10 35 219 1.3E-37 T 28-03-2018 SMD44_RS08625 9a8767fb32d14810645f1bea4321d922 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 53 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08625 9a8767fb32d14810645f1bea4321d922 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 84 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08625 9a8767fb32d14810645f1bea4321d922 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 86 9.0E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08625 9a8767fb32d14810645f1bea4321d922 219 SUPERFAMILY SSF46689 28 100 3.34E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS26815 1f7205eba4858640ba53fb7dfb4684f1 134 Pfam PF13466 STAS domain 23 103 6.2E-13 T 28-03-2018 IPR002645 STAS domain SMD44_RS26815 1f7205eba4858640ba53fb7dfb4684f1 134 SUPERFAMILY SSF52091 21 106 2.94E-9 T 28-03-2018 IPR002645 STAS domain SMD44_RS26815 1f7205eba4858640ba53fb7dfb4684f1 134 Gene3D G3DSA:3.30.750.24 15 133 5.8E-9 T 28-03-2018 IPR002645 STAS domain SMD44_RS14080 43db0fe5a7dd3ddc4e07d42d8b3a706a 503 SUPERFAMILY SSF53244 363 501 3.66E-25 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS14080 43db0fe5a7dd3ddc4e07d42d8b3a706a 503 Pfam PF08245 Mur ligase middle domain 106 333 2.5E-15 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS14080 43db0fe5a7dd3ddc4e07d42d8b3a706a 503 Pfam PF02875 Mur ligase family, glutamate ligase domain 362 439 1.6E-10 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS14080 43db0fe5a7dd3ddc4e07d42d8b3a706a 503 TIGRFAM TIGR01499 folC: bifunctional protein FolC 84 497 7.4E-100 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SMD44_RS14080 43db0fe5a7dd3ddc4e07d42d8b3a706a 503 SUPERFAMILY SSF53623 64 359 2.14E-90 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS14080 43db0fe5a7dd3ddc4e07d42d8b3a706a 503 Gene3D G3DSA:3.40.1190.10 57 362 6.8E-85 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS14080 43db0fe5a7dd3ddc4e07d42d8b3a706a 503 Gene3D G3DSA:3.90.190.20 363 503 2.4E-29 T 28-03-2018 SMD44_RS14080 43db0fe5a7dd3ddc4e07d42d8b3a706a 503 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 202 217 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 Gene3D G3DSA:1.10.10.10 1 84 5.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 Gene3D G3DSA:3.40.190.10 179 270 4.3E-18 T 28-03-2018 SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 Gene3D G3DSA:3.40.190.10 91 178 6.4E-18 T 28-03-2018 SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 SUPERFAMILY SSF53850 93 296 1.16E-28 T 28-03-2018 SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 Pfam PF03466 LysR substrate binding domain 92 294 1.8E-34 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 9.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 9.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 9.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS15155 26e0973c400b52fd5df8e43b3d7d50c4 302 SUPERFAMILY SSF46785 2 81 1.07E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37055 ec054fc4356494d2fdeade3904db5d6d 374 Gene3D G3DSA:3.40.50.2300 204 339 1.2E-33 T 28-03-2018 SMD44_RS37055 ec054fc4356494d2fdeade3904db5d6d 374 Gene3D G3DSA:3.40.50.2300 86 203 1.5E-23 T 28-03-2018 SMD44_RS37055 ec054fc4356494d2fdeade3904db5d6d 374 Pfam PF13407 Periplasmic binding protein domain 99 347 3.2E-52 T 28-03-2018 IPR025997 Periplasmic binding protein SMD44_RS37055 ec054fc4356494d2fdeade3904db5d6d 374 SUPERFAMILY SSF53822 86 367 2.36E-74 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS02790 4a54bf15db84806c95f5445f44b8cc33 458 Gene3D G3DSA:3.40.309.10 248 434 3.6E-53 T 28-03-2018 SMD44_RS02790 4a54bf15db84806c95f5445f44b8cc33 458 Gene3D G3DSA:3.40.605.10 2 247 4.3E-69 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS02790 4a54bf15db84806c95f5445f44b8cc33 458 SUPERFAMILY SSF53720 5 452 7.85E-125 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS02790 4a54bf15db84806c95f5445f44b8cc33 458 Pfam PF00171 Aldehyde dehydrogenase family 6 449 9.8E-121 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS02790 4a54bf15db84806c95f5445f44b8cc33 458 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS02790 4a54bf15db84806c95f5445f44b8cc33 458 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 Gene3D G3DSA:2.40.180.10 1 357 3.1E-161 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 PRINTS PR00067 Catalase signature 20 43 1.3E-69 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 PRINTS PR00067 Catalase signature 104 121 1.3E-69 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 PRINTS PR00067 Catalase signature 83 101 1.3E-69 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 PRINTS PR00067 Catalase signature 320 346 1.3E-69 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 PRINTS PR00067 Catalase signature 288 315 1.3E-69 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 PRINTS PR00067 Catalase signature 123 141 1.3E-69 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 SMART SM01060 7 395 5.9E-276 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 Pfam PF06628 Catalase-related immune-responsive 420 482 1.8E-21 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 PIRSF PIRSF038928 1 488 1.2E-216 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 Pfam PF00199 Catalase 7 392 3.0E-184 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS33325 a6c7941447af23bcdce00310ea60292b 488 SUPERFAMILY SSF56634 3 483 4.71E-204 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS20410 bad230b12dfdb11f13bff8746fef7f19 409 Gene3D G3DSA:3.90.350.10 75 378 2.8E-35 T 28-03-2018 IPR014736 Transposase, Tn5-like, core SMD44_RS20410 bad230b12dfdb11f13bff8746fef7f19 409 SUPERFAMILY SSF53098 10 406 2.88E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS20410 bad230b12dfdb11f13bff8746fef7f19 409 Pfam PF13546 DDE superfamily endonuclease 20 279 3.5E-89 T 28-03-2018 SMD44_RS27775 86fda43b505a2c7cae8c1160bc71254f 423 SUPERFAMILY SSF55874 265 381 1.81E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27775 86fda43b505a2c7cae8c1160bc71254f 423 Gene3D G3DSA:3.30.565.10 250 406 7.0E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27775 86fda43b505a2c7cae8c1160bc71254f 423 Pfam PF07730 Histidine kinase 185 249 1.1E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 PRINTS PR01183 Ribonucleotide reductase large chain signature 310 329 5.6E-48 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 PRINTS PR01183 Ribonucleotide reductase large chain signature 547 570 5.6E-48 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 PRINTS PR01183 Ribonucleotide reductase large chain signature 519 541 5.6E-48 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 PRINTS PR01183 Ribonucleotide reductase large chain signature 481 504 5.6E-48 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 PRINTS PR01183 Ribonucleotide reductase large chain signature 442 453 5.6E-48 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 PRINTS PR01183 Ribonucleotide reductase large chain signature 612 639 5.6E-48 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 SUPERFAMILY SSF51998 233 661 2.14E-173 T 28-03-2018 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 SUPERFAMILY SSF51998 692 762 2.14E-173 T 28-03-2018 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 Pfam PF02867 Ribonucleotide reductase, barrel domain 234 757 5.7E-175 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 154 230 5.4E-21 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 Gene3D G3DSA:3.20.70.20 135 764 4.3E-201 T 28-03-2018 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 601 623 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 157 761 2.8E-224 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28320 d7dc63d8e6cf919f8c4c8827b7112bf3 804 SUPERFAMILY SSF48168 32 232 1.83E-43 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01925 c3e7f9a81b75cd7f33e331f789d79dd5 319 SUPERFAMILY SSF53901 17 318 1.97E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01925 c3e7f9a81b75cd7f33e331f789d79dd5 319 Gene3D G3DSA:3.40.47.10 15 168 2.4E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01925 c3e7f9a81b75cd7f33e331f789d79dd5 319 Gene3D G3DSA:3.40.47.10 169 319 6.1E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01925 c3e7f9a81b75cd7f33e331f789d79dd5 319 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 230 318 1.7E-20 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01925 c3e7f9a81b75cd7f33e331f789d79dd5 319 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 115 191 1.2E-16 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 Gene3D G3DSA:1.20.140.10 225 384 6.6E-54 T 28-03-2018 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 Gene3D G3DSA:1.10.540.10 3 123 3.3E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 PIRSF PIRSF016578 30 232 4.6E-5 T 28-03-2018 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 PIRSF PIRSF016578 241 384 6.8E-10 T 28-03-2018 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 383 8.9E-44 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 Gene3D G3DSA:2.40.110.10 124 224 7.3E-35 T 28-03-2018 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 2.0E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 SUPERFAMILY SSF56645 4 246 4.32E-77 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 223 7.1E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS14940 d2ce4eb4a6d04a54379f99caecea63f6 385 SUPERFAMILY SSF47203 233 383 4.35E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS32875 3fe7b4213896f6b924d2415a507d2acf 318 SUPERFAMILY SSF46689 214 264 3.67E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS32875 3fe7b4213896f6b924d2415a507d2acf 318 SMART SM00342 231 314 1.5E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS32875 3fe7b4213896f6b924d2415a507d2acf 318 SUPERFAMILY SSF46689 267 315 8.51E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS32875 3fe7b4213896f6b924d2415a507d2acf 318 Gene3D G3DSA:1.10.10.60 217 269 2.8E-10 T 28-03-2018 SMD44_RS32875 3fe7b4213896f6b924d2415a507d2acf 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 268 310 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS32875 3fe7b4213896f6b924d2415a507d2acf 318 Gene3D G3DSA:1.10.10.60 270 317 3.3E-13 T 28-03-2018 SMD44_RS32875 3fe7b4213896f6b924d2415a507d2acf 318 Pfam PF12833 Helix-turn-helix domain 237 314 2.7E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS32875 3fe7b4213896f6b924d2415a507d2acf 318 Pfam PF12852 Cupin 2 198 5.8E-45 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMD44_RS13855 484f7ead4329d5cd786980b6e809c8e6 81 Gene3D G3DSA:3.30.70.970 1 80 3.4E-8 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain SMD44_RS37505 b53a102f1c457e3d97248aa6c100c878 337 SUPERFAMILY SSF47413 9 69 1.2E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS37505 b53a102f1c457e3d97248aa6c100c878 337 Gene3D G3DSA:1.10.260.40 11 63 5.1E-22 T 28-03-2018 SMD44_RS37505 b53a102f1c457e3d97248aa6c100c878 337 Gene3D G3DSA:3.40.50.2300 184 316 7.3E-26 T 28-03-2018 SMD44_RS37505 b53a102f1c457e3d97248aa6c100c878 337 SUPERFAMILY SSF53822 70 336 8.48E-29 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS37505 b53a102f1c457e3d97248aa6c100c878 337 Pfam PF13377 Periplasmic binding protein-like domain 179 337 1.4E-25 T 28-03-2018 SMD44_RS37505 b53a102f1c457e3d97248aa6c100c878 337 Gene3D G3DSA:3.40.50.2300 64 183 1.8E-14 T 28-03-2018 SMD44_RS37505 b53a102f1c457e3d97248aa6c100c878 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 57 2.0E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS37505 b53a102f1c457e3d97248aa6c100c878 337 SMART SM00354 9 81 5.5E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS15940 3395c94404871adb0516057cb540fd2c 786 Pfam PF00580 UvrD/REP helicase N-terminal domain 540 603 2.4E-6 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SMD44_RS15940 3395c94404871adb0516057cb540fd2c 786 Gene3D G3DSA:3.40.50.300 629 781 6.2E-13 T 28-03-2018 SMD44_RS15940 3395c94404871adb0516057cb540fd2c 786 SUPERFAMILY SSF52540 531 778 7.47E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15940 3395c94404871adb0516057cb540fd2c 786 SUPERFAMILY SSF52540 210 288 7.47E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15940 3395c94404871adb0516057cb540fd2c 786 SUPERFAMILY SSF52540 402 456 7.47E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15940 3395c94404871adb0516057cb540fd2c 786 Gene3D G3DSA:3.40.50.300 216 615 1.7E-31 T 28-03-2018 SMD44_RS15940 3395c94404871adb0516057cb540fd2c 786 Pfam PF13538 UvrD-like helicase C-terminal domain 726 767 3.1E-7 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain SMD44_RS43050 7973828d3f9e9df2f85af5bc06ebaa61 580 SUPERFAMILY SSF48452 425 573 1.52E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS43050 7973828d3f9e9df2f85af5bc06ebaa61 580 Pfam PF03704 Bacterial transcriptional activator domain 429 570 3.1E-7 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS43050 7973828d3f9e9df2f85af5bc06ebaa61 580 Gene3D G3DSA:1.25.40.10 425 577 1.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS43050 7973828d3f9e9df2f85af5bc06ebaa61 580 Gene3D G3DSA:1.10.10.10 322 413 2.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS43050 7973828d3f9e9df2f85af5bc06ebaa61 580 SMART SM01043 428 570 5.8E-11 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 SUPERFAMILY SSF50494 172 355 9.03E-36 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 308 319 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 Pfam PF02983 Alpha-lytic protease prodomain 100 153 1.7E-10 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 PIRSF PIRSF001134 1 358 4.7E-115 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 Gene3D G3DSA:3.30.300.50 39 96 6.8E-14 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 Pfam PF00089 Trypsin 195 349 3.5E-11 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 199 204 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 197 211 5.6E-43 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 259 279 5.6E-43 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 299 322 5.6E-43 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 280 297 5.6E-43 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 323 337 5.6E-43 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 Gene3D G3DSA:2.40.10.10 171 256 8.2E-23 T 28-03-2018 SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 Gene3D G3DSA:3.30.300.50 97 165 2.2E-15 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS14265 51f79cc4b4b2770bc39030e6499ca899 358 Gene3D G3DSA:2.40.10.10 257 345 2.8E-18 T 28-03-2018 SMD44_RS24005 a5baef2605ac95b0220f7bc68696785d 617 Pfam PF00920 Dehydratase family 35 609 2.4E-215 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD44_RS24005 a5baef2605ac95b0220f7bc68696785d 617 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.9 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD44_RS24005 a5baef2605ac95b0220f7bc68696785d 617 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 515 526 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD44_RS24005 a5baef2605ac95b0220f7bc68696785d 617 SUPERFAMILY SSF143975 4 426 8.5E-129 T 28-03-2018 SMD44_RS24005 a5baef2605ac95b0220f7bc68696785d 617 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD44_RS24005 a5baef2605ac95b0220f7bc68696785d 617 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 1.2E-235 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD44_RS24005 a5baef2605ac95b0220f7bc68696785d 617 Gene3D G3DSA:3.40.50.2300 16 164 2.1E-4 T 28-03-2018 SMD44_RS24005 a5baef2605ac95b0220f7bc68696785d 617 SUPERFAMILY SSF52016 427 613 2.12E-61 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD44_RS08700 1a6c1e9759d52640df30fab2cadee370 273 Gene3D G3DSA:3.40.50.1110 35 261 2.5E-37 T 28-03-2018 SMD44_RS08700 1a6c1e9759d52640df30fab2cadee370 273 SUPERFAMILY SSF52266 41 260 1.02E-60 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS08700 1a6c1e9759d52640df30fab2cadee370 273 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 43 260 3.1E-22 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 SUPERFAMILY SSF55486 52 354 6.96E-80 T 28-03-2018 SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 138 158 8.0E-29 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 276 292 8.0E-29 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 174 190 8.0E-29 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 195 206 8.0E-29 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 Gene3D G3DSA:3.10.170.10 8 187 1.2E-56 T 28-03-2018 SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 85 183 4.9E-25 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 Gene3D G3DSA:1.10.390.10 188 355 1.4E-54 T 28-03-2018 SMD44_RS13695 fabd0796f97d32b7769415df9eb25410 357 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 186 354 1.3E-51 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.366.10 2300 2417 3.3E-26 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.366.10 715 836 2.7E-28 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 376 498 7.2E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1961 2079 1.1E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.47.10 1848 2011 1.8E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.47.10 259 426 1.8E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF51735 951 1169 1.08E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF47336 1481 1598 3.66E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.10.129.10 2488 2609 1.4E-7 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 534 831 3.1E-124 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2116 2413 8.8E-122 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF53901 1581 1955 4.62E-108 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.366.10 2109 2251 2.2E-50 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.50.720 1180 1448 2.6E-50 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1746 1762 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF00698 Acyl transferase domain 534 850 1.5E-59 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF00698 Acyl transferase domain 2116 2432 1.6E-53 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SMART SM00825 Beta-ketoacyl synthase 1585 2013 1.1E-230 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SMART SM00825 Beta-ketoacyl synthase 1 428 3.0E-219 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1188 1368 1.1E-60 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF55048 2239 2303 5.1E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF53901 1 372 3.37E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SMART SM01294 1487 1554 1.5E-6 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.30.70.250 668 714 1.7E-19 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.30.70.250 2252 2299 3.1E-18 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1513 1528 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.366.10 530 667 2.3E-46 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF55048 657 721 9.68E-13 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF14765 Polyketide synthase dehydratase 2482 2760 1.4E-61 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 5.8E-87 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1583 1833 8.7E-96 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF08659 KR domain 1188 1366 3.1E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF51735 1186 1411 5.75E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF52151 2304 2401 1.2E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF52151 2113 2240 1.2E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.47.10 1 256 2.2E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:3.40.47.10 1577 1845 2.8E-91 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Gene3D G3DSA:1.10.1200.10 1465 1559 1.1E-22 T 28-03-2018 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SMART SM00823 Phosphopantetheine attachment site 1486 1558 4.2E-33 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SMART SM00826 2482 2646 4.5E-85 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 157 173 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF52151 722 819 7.06E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 SUPERFAMILY SSF52151 531 658 7.06E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 373 3.1E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1841 1958 4.4E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36780 529e1d531840897b6f7f9462d4e0ca99 2871 Pfam PF00550 Phosphopantetheine attachment site 1488 1554 1.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 195 3.8E-38 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 SUPERFAMILY SSF46929 149 200 2.09E-8 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 Gene3D G3DSA:1.10.8.10 151 202 7.3E-17 T 28-03-2018 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 SMART SM00278 72 91 50.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 SMART SM00278 107 126 0.033 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 Gene3D G3DSA:1.10.150.280 57 80 0.15 T 28-03-2018 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 Pfam PF14520 Helix-hairpin-helix domain 71 129 2.5E-15 T 28-03-2018 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 Pfam PF01330 RuvA N terminal domain 1 61 4.6E-19 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 Pfam PF07499 RuvA, C-terminal domain 150 198 3.7E-10 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 SUPERFAMILY SSF47781 65 132 8.4E-19 T 28-03-2018 IPR010994 RuvA domain 2-like SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 Gene3D G3DSA:2.40.50.140 1 56 2.7E-22 T 28-03-2018 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 Gene3D G3DSA:1.10.150.20 81 133 1.4E-14 T 28-03-2018 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 199 26.694 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SMD44_RS07450 65b77b74fb2bfb5a0c84a93c3b7b9577 202 SUPERFAMILY SSF50249 1 62 5.31E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS18065 22f471439f5c86cd1e74f5cf19f8dc46 349 SUPERFAMILY SSF50129 3 181 7.15E-51 T 28-03-2018 IPR011032 GroES-like SMD44_RS18065 22f471439f5c86cd1e74f5cf19f8dc46 349 Gene3D G3DSA:3.40.50.720 184 290 5.8E-20 T 28-03-2018 SMD44_RS18065 22f471439f5c86cd1e74f5cf19f8dc46 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS18065 22f471439f5c86cd1e74f5cf19f8dc46 349 SUPERFAMILY SSF51735 147 314 3.38E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS18065 22f471439f5c86cd1e74f5cf19f8dc46 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 141 1.1E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS18065 22f471439f5c86cd1e74f5cf19f8dc46 349 SMART SM00829 3 347 5.1E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS18065 22f471439f5c86cd1e74f5cf19f8dc46 349 Gene3D G3DSA:3.90.180.10 1 183 5.4E-53 T 28-03-2018 SMD44_RS18065 22f471439f5c86cd1e74f5cf19f8dc46 349 Pfam PF00107 Zinc-binding dehydrogenase 185 301 3.8E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS19165 6806ff9d71542ee91aa2e4c1c9fb2fc6 287 SUPERFAMILY SSF55961 16 154 5.3E-34 T 28-03-2018 SMD44_RS19165 6806ff9d71542ee91aa2e4c1c9fb2fc6 287 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 31 142 1.5E-15 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMD44_RS19165 6806ff9d71542ee91aa2e4c1c9fb2fc6 287 Gene3D G3DSA:3.30.530.20 2 169 1.3E-31 T 28-03-2018 IPR023393 START-like domain SMD44_RS19165 6806ff9d71542ee91aa2e4c1c9fb2fc6 287 Gene3D G3DSA:3.30.530.20 175 284 0.019 T 28-03-2018 IPR023393 START-like domain SMD44_RS23635 ca587bbf9ad0b38e1b31ae844180fc5e 183 SUPERFAMILY SSF109854 7 165 3.36E-36 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS23635 ca587bbf9ad0b38e1b31ae844180fc5e 183 Pfam PF04978 Protein of unknown function (DUF664) 17 166 4.7E-45 T 28-03-2018 IPR007061 Protein of unknown function DUF664 SMD44_RS23635 ca587bbf9ad0b38e1b31ae844180fc5e 183 Gene3D G3DSA:1.20.120.450 12 162 3.2E-31 T 28-03-2018 SMD44_RS03440 6116f6dc97f443f7e48ee5a0e4bb5f50 421 Gene3D G3DSA:3.40.50.1820 193 416 5.1E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS03440 6116f6dc97f443f7e48ee5a0e4bb5f50 421 Pfam PF12146 Serine aminopeptidase, S33 215 321 4.4E-10 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SMD44_RS03440 6116f6dc97f443f7e48ee5a0e4bb5f50 421 SUPERFAMILY SSF53474 103 418 8.52E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36705 dfc3f71f2324a23188c1e657189f7045 632 Pfam PF00664 ABC transporter transmembrane region 44 312 3.9E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS36705 dfc3f71f2324a23188c1e657189f7045 632 SUPERFAMILY SSF52540 355 615 3.94E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS36705 dfc3f71f2324a23188c1e657189f7045 632 Gene3D G3DSA:3.40.50.300 346 620 4.5E-71 T 28-03-2018 SMD44_RS36705 dfc3f71f2324a23188c1e657189f7045 632 Gene3D G3DSA:1.20.1560.10 7 345 2.5E-65 T 28-03-2018 SMD44_RS36705 dfc3f71f2324a23188c1e657189f7045 632 SUPERFAMILY SSF90123 28 348 8.5E-72 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS36705 dfc3f71f2324a23188c1e657189f7045 632 ProSitePatterns PS00211 ABC transporters family signature. 516 530 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS36705 dfc3f71f2324a23188c1e657189f7045 632 SMART SM00382 404 590 5.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS36705 dfc3f71f2324a23188c1e657189f7045 632 Pfam PF00005 ABC transporter 395 544 2.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS01965 b353b9a7c1c968ef9c83c9a89081e3fb 175 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 88 170 1.7E-6 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS01965 b353b9a7c1c968ef9c83c9a89081e3fb 175 Gene3D G3DSA:1.10.357.10 8 175 1.3E-10 T 28-03-2018 SMD44_RS01965 b353b9a7c1c968ef9c83c9a89081e3fb 175 SUPERFAMILY SSF48498 67 173 3.78E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 SUPERFAMILY SSF52540 552 856 3.85E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Gene3D G3DSA:3.40.50.300 158 344 6.9E-24 T 28-03-2018 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 SMART SM00382 199 345 5.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 SMART SM00382 603 796 1.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 338 3.2E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 SMART SM01086 770 859 7.0E-39 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Gene3D G3DSA:1.10.8.60 345 553 9.8E-45 T 28-03-2018 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Gene3D G3DSA:1.10.8.60 770 860 1.8E-25 T 28-03-2018 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 SUPERFAMILY SSF52540 160 551 3.74E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 770 850 1.9E-27 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 637 655 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 857 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Gene3D G3DSA:3.40.50.300 558 769 9.3E-50 T 28-03-2018 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 SUPERFAMILY SSF81923 4 157 3.43E-29 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Gene3D G3DSA:1.10.1780.10 1 152 5.6E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Pfam PF07724 AAA domain (Cdc48 subfamily) 602 763 6.4E-53 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 1.5E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 19 68 0.0018 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 4.2E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 4.2E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 714 728 4.2E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SMD44_RS22555 840e13baf02bf80e5a296d30ff418a63 875 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 4.2E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SMD44_RS18895 36092f2b092c787f65ee4ec3b4558ca7 185 SUPERFAMILY SSF143744 52 183 6.28E-32 T 28-03-2018 SMD44_RS18895 36092f2b092c787f65ee4ec3b4558ca7 185 Pfam PF03928 Haem-degrading 58 180 2.0E-28 T 28-03-2018 IPR005624 Haem-degrading SMD44_RS19745 9afb4b7ef5fb988e3eba7e4fefb4b115 519 Gene3D G3DSA:3.60.21.10 258 467 1.3E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS19745 9afb4b7ef5fb988e3eba7e4fefb4b115 519 Pfam PF00149 Calcineurin-like phosphoesterase 264 430 7.0E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS19745 9afb4b7ef5fb988e3eba7e4fefb4b115 519 SUPERFAMILY SSF56300 258 451 1.83E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 34.034 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 SUPERFAMILY SSF55920 4 253 5.1E-69 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 1.9E-16 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.9E-16 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.9E-16 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 1.9E-16 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 254 5.4E-72 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 Pfam PF00557 Metallopeptidase family M24 11 246 3.0E-43 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS33955 eda87d9f7ac02b42a3522488e705ab91 255 Gene3D G3DSA:3.90.230.10 1 255 1.3E-66 T 28-03-2018 SMD44_RS12825 7d3473c5f4ca56a5a2f5806ed2c929b6 142 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 10 141 2.0E-56 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 SMD44_RS12825 7d3473c5f4ca56a5a2f5806ed2c929b6 142 Pfam PF02566 OsmC-like protein 43 139 7.5E-19 T 28-03-2018 IPR003718 OsmC/Ohr family SMD44_RS12825 7d3473c5f4ca56a5a2f5806ed2c929b6 142 Gene3D G3DSA:2.20.25.10 5 48 3.2E-18 T 28-03-2018 SMD44_RS12825 7d3473c5f4ca56a5a2f5806ed2c929b6 142 SUPERFAMILY SSF82784 9 141 2.22E-43 T 28-03-2018 IPR003718 OsmC/Ohr family SMD44_RS12825 7d3473c5f4ca56a5a2f5806ed2c929b6 142 Gene3D G3DSA:3.30.300.20 49 142 9.5E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS38615 4e15742853e7e82751ba272f9c9ca44e 111 SUPERFAMILY SSF52540 2 44 4.64E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS38615 4e15742853e7e82751ba272f9c9ca44e 111 Gene3D G3DSA:3.40.50.300 35 94 1.9E-4 T 28-03-2018 SMD44_RS38615 4e15742853e7e82751ba272f9c9ca44e 111 Gene3D G3DSA:3.40.50.300 1 34 1.1E-6 T 28-03-2018 SMD44_RS38615 4e15742853e7e82751ba272f9c9ca44e 111 Pfam PF13191 AAA ATPase domain 2 81 2.7E-10 T 28-03-2018 SMD44_RS26530 8904efc52edc864403b059684ef3b5df 141 Gene3D G3DSA:3.10.180.10 1 139 1.9E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS26530 8904efc52edc864403b059684ef3b5df 141 SUPERFAMILY SSF54593 15 132 1.11E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 Gene3D G3DSA:3.50.50.60 161 282 1.5E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 466 1.2E-167 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 Gene3D G3DSA:3.50.50.60 283 363 4.7E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 3.1E-66 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 1.6E-33 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.5E-37 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 3.5E-37 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 3.5E-37 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 3.5E-37 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.5E-37 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 SUPERFAMILY SSF55424 344 466 1.1E-37 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 Gene3D G3DSA:3.30.390.30 364 461 4.3E-33 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 PIRSF PIRSF000350 1 463 9.2E-85 T 28-03-2018 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 SUPERFAMILY SSF51905 1 337 9.97E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 328 9.0E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS05460 70fbdf6444a5f6694e82930e814aba71 467 Gene3D G3DSA:3.50.50.60 1 160 6.4E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS09855 c233e4e2d05002d245d32b7c71ed5842 287 SUPERFAMILY SSF161098 15 287 2.43E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS09855 c233e4e2d05002d245d32b7c71ed5842 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 267 9.9E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS09855 c233e4e2d05002d245d32b7c71ed5842 287 Gene3D G3DSA:1.10.3720.10 20 277 4.6E-32 T 28-03-2018 SMD44_RS11240 46f4959799d82d3e7f526879ba666ca7 253 Pfam PF01553 Acyltransferase 17 147 8.3E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS11240 46f4959799d82d3e7f526879ba666ca7 253 SMART SM00563 29 150 1.9E-33 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS11240 46f4959799d82d3e7f526879ba666ca7 253 SUPERFAMILY SSF69593 7 218 2.22E-50 T 28-03-2018 SMD44_RS11240 46f4959799d82d3e7f526879ba666ca7 253 Gene3D G3DSA:3.40.1130.10 9 226 3.8E-57 T 28-03-2018 SMD44_RS32890 337382a4ef55a0e9977f8c9d4381c880 141 SUPERFAMILY SSF55811 9 139 3.66E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS32890 337382a4ef55a0e9977f8c9d4381c880 141 PRINTS PR00502 NUDIX hydrolase family signature 50 65 8.7E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS32890 337382a4ef55a0e9977f8c9d4381c880 141 PRINTS PR00502 NUDIX hydrolase family signature 36 50 8.7E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS32890 337382a4ef55a0e9977f8c9d4381c880 141 Pfam PF00293 NUDIX domain 8 119 2.0E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS32890 337382a4ef55a0e9977f8c9d4381c880 141 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS32890 337382a4ef55a0e9977f8c9d4381c880 141 Gene3D G3DSA:3.90.79.10 5 141 1.5E-24 T 28-03-2018 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 Pfam PF01926 50S ribosome-binding GTPase 60 174 1.6E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 Pfam PF01926 50S ribosome-binding GTPase 234 352 1.1E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 408 486 3.2E-24 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 Gene3D G3DSA:3.30.300.20 404 487 1.1E-27 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 Gene3D G3DSA:3.40.50.300 3 104 3.6E-15 T 28-03-2018 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 SUPERFAMILY SSF52540 192 490 1.01E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 PIRSF PIRSF006485 56 494 1.0E-156 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 58 486 7.8E-157 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 Hamap MF_00195 GTPase Der [der]. 57 489 35.349 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 284 299 5.9E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 235 255 5.9E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 SUPERFAMILY SSF52540 59 222 3.58E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 Gene3D G3DSA:3.40.50.300 105 227 1.4E-22 T 28-03-2018 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 60 179 1.7E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 233 399 1.6E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 Gene3D G3DSA:3.40.50.300 230 403 6.2E-31 T 28-03-2018 SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 SMART SM00382 56 192 0.32 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS09035 98a54dc0a674f61bdfa3d0348175d762 500 SMART SM00382 231 374 0.0014 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS13385 5f5d5f7abaf119ef840244fa82905fd2 189 Gene3D G3DSA:3.40.50.360 1 186 1.3E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS13385 5f5d5f7abaf119ef840244fa82905fd2 189 SUPERFAMILY SSF52218 2 165 2.68E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS13385 5f5d5f7abaf119ef840244fa82905fd2 189 Pfam PF03358 NADPH-dependent FMN reductase 2 144 2.0E-41 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD44_RS28850 44d25f0278233db21c4981dde153783f 432 Pfam PF00464 Serine hydroxymethyltransferase 19 395 3.3E-134 T 28-03-2018 SMD44_RS28850 44d25f0278233db21c4981dde153783f 432 PIRSF PIRSF000412 1 419 6.1E-143 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD44_RS28850 44d25f0278233db21c4981dde153783f 432 Gene3D G3DSA:3.90.1150.10 283 421 3.2E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS28850 44d25f0278233db21c4981dde153783f 432 SUPERFAMILY SSF53383 15 422 4.54E-147 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS28850 44d25f0278233db21c4981dde153783f 432 Gene3D G3DSA:3.40.640.10 47 282 4.6E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS28850 44d25f0278233db21c4981dde153783f 432 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 17 422 45.588 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD44_RS38305 92d5bfe57832f865512b14394520fdda 433 Pfam PF00561 alpha/beta hydrolase fold 49 221 8.1E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS38305 92d5bfe57832f865512b14394520fdda 433 Gene3D G3DSA:3.40.50.1820 262 430 1.3E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38305 92d5bfe57832f865512b14394520fdda 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 1.9E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS38305 92d5bfe57832f865512b14394520fdda 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 140 154 1.9E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS38305 92d5bfe57832f865512b14394520fdda 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 59 1.9E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS38305 92d5bfe57832f865512b14394520fdda 433 Gene3D G3DSA:3.40.50.1820 29 261 1.6E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38305 92d5bfe57832f865512b14394520fdda 433 SUPERFAMILY SSF53474 17 292 8.73E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS18575 29d8e2c900434352dfa520db70a46e61 469 SUPERFAMILY SSF103473 89 448 9.42E-20 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS18575 29d8e2c900434352dfa520db70a46e61 469 Pfam PF07690 Major Facilitator Superfamily 87 421 1.4E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS18575 29d8e2c900434352dfa520db70a46e61 469 Gene3D G3DSA:1.20.1250.20 62 271 1.6E-9 T 28-03-2018 SMD44_RS18575 29d8e2c900434352dfa520db70a46e61 469 Gene3D G3DSA:1.20.1250.20 274 457 1.6E-7 T 28-03-2018 SMD44_RS31525 03164492150709ef4c37fd863dbcc4f0 296 Gene3D G3DSA:1.10.10.10 57 141 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31525 03164492150709ef4c37fd863dbcc4f0 296 Pfam PF00392 Bacterial regulatory proteins, gntR family 70 129 2.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS31525 03164492150709ef4c37fd863dbcc4f0 296 SUPERFAMILY SSF48008 155 281 1.7E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS31525 03164492150709ef4c37fd863dbcc4f0 296 SMART SM00345 71 129 1.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS31525 03164492150709ef4c37fd863dbcc4f0 296 Pfam PF07729 FCD domain 158 280 3.4E-22 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS31525 03164492150709ef4c37fd863dbcc4f0 296 SUPERFAMILY SSF46785 63 133 2.27E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31525 03164492150709ef4c37fd863dbcc4f0 296 Gene3D G3DSA:1.20.120.530 152 286 8.5E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS31525 03164492150709ef4c37fd863dbcc4f0 296 SMART SM00895 158 282 8.9E-23 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 Pfam PF00931 NB-ARC domain 8 245 6.0E-8 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 PRINTS PR00364 Disease resistance protein signature 88 102 5.0E-10 T 28-03-2018 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 PRINTS PR00364 Disease resistance protein signature 176 190 5.0E-10 T 28-03-2018 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 PRINTS PR00364 Disease resistance protein signature 9 24 5.0E-10 T 28-03-2018 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 SUPERFAMILY SSF48452 420 534 1.86E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 Pfam PF13424 Tetratricopeptide repeat 543 614 2.3E-11 T 28-03-2018 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 Gene3D G3DSA:1.25.40.10 463 633 1.5E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 Gene3D G3DSA:3.40.50.300 1 137 1.8E-12 T 28-03-2018 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 Gene3D G3DSA:1.10.10.10 224 312 5.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 Gene3D G3DSA:1.25.40.10 409 462 0.0018 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 SUPERFAMILY SSF52540 6 237 5.35E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 SUPERFAMILY SSF48452 505 619 1.96E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 SMART SM00028 544 577 54.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS19760 4355ac5df4929a818e19c4da42814afe 634 SMART SM00028 584 617 0.54 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 Gene3D G3DSA:1.10.260.40 7 70 1.2E-12 T 28-03-2018 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 Gene3D G3DSA:1.10.10.60 71 119 6.9E-13 T 28-03-2018 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 Pfam PF00440 Bacterial regulatory proteins, tetR family 98 144 1.3E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 SUPERFAMILY SSF47413 10 67 5.09E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 Gene3D G3DSA:1.10.260.40 120 156 2.2E-11 T 28-03-2018 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 167 283 2.2E-27 T 28-03-2018 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 SMART SM00530 10 65 3.3E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 98 111 9.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 119 142 9.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 SUPERFAMILY SSF46689 85 168 1.33E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 Gene3D G3DSA:1.10.357.10 157 283 3.4E-21 T 28-03-2018 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 Pfam PF13560 Helix-turn-helix domain 16 62 7.1E-7 T 28-03-2018 SMD44_RS35020 141958846779a0ff14aff9f57344e407 285 SUPERFAMILY SSF48498 165 264 7.55E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS42360 636f5a32f316fd9512ff684a5a4a1a88 116 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 75 17.513 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS42360 636f5a32f316fd9512ff684a5a4a1a88 116 Pfam PF02467 Transcription factor WhiB 7 70 1.1E-22 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS27235 f381979e38836ce9a4a5111371d85e73 362 Gene3D G3DSA:3.40.1190.20 14 338 1.7E-66 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS27235 f381979e38836ce9a4a5111371d85e73 362 Pfam PF00294 pfkB family carbohydrate kinase 15 315 1.3E-49 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS27235 f381979e38836ce9a4a5111371d85e73 362 SUPERFAMILY SSF53613 15 320 6.39E-68 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS12790 98e6e338bfa59b8ead2ac45a7c1f1e1d 353 Gene3D G3DSA:3.40.50.1110 106 352 3.3E-33 T 28-03-2018 SMD44_RS12790 98e6e338bfa59b8ead2ac45a7c1f1e1d 353 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 114 335 3.5E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS12790 98e6e338bfa59b8ead2ac45a7c1f1e1d 353 SUPERFAMILY SSF52266 109 248 1.22E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS12790 98e6e338bfa59b8ead2ac45a7c1f1e1d 353 SUPERFAMILY SSF52266 277 343 1.22E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS18365 39936edaaf998c90e38a3f4ab0cc108a 416 SUPERFAMILY SSF47090 132 189 1.1E-5 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS18365 39936edaaf998c90e38a3f4ab0cc108a 416 Gene3D G3DSA:1.10.101.10 133 389 2.9E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS18365 39936edaaf998c90e38a3f4ab0cc108a 416 Pfam PF01471 Putative peptidoglycan binding domain 144 178 8.8E-5 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS05115 923ff72ffbcdf4fe2737a5e42817b021 218 Pfam PF12802 MarR family 92 149 6.4E-9 T 28-03-2018 SMD44_RS05115 923ff72ffbcdf4fe2737a5e42817b021 218 Gene3D G3DSA:1.10.10.10 30 207 1.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05115 923ff72ffbcdf4fe2737a5e42817b021 218 SMART SM00347 86 189 9.2E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS05115 923ff72ffbcdf4fe2737a5e42817b021 218 SUPERFAMILY SSF46785 53 201 2.18E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12640 e261e84df01aef1bb7aea11e976bb2cc 207 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 185 5.9E-48 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD44_RS12640 e261e84df01aef1bb7aea11e976bb2cc 207 SUPERFAMILY SSF51569 2 204 1.59E-51 T 28-03-2018 SMD44_RS12640 e261e84df01aef1bb7aea11e976bb2cc 207 Pfam PF01081 KDPG and KHG aldolase 7 185 2.3E-39 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD44_RS12640 e261e84df01aef1bb7aea11e976bb2cc 207 Gene3D G3DSA:3.20.20.70 2 205 8.0E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 176 326 1.9E-40 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 429 565 1.5E-9 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 105 165 3.0E-20 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 352 416 4.3E-14 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 Gene3D G3DSA:3.30.413.10 177 293 2.3E-28 T 28-03-2018 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 474 490 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 SUPERFAMILY SSF56014 425 566 3.27E-36 T 28-03-2018 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 SUPERFAMILY SSF55124 345 421 9.32E-19 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 Gene3D G3DSA:3.90.480.10 294 423 6.0E-27 T 28-03-2018 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 PRINTS PR00397 Sirohaem Fe-binding site signature 474 492 1.4E-9 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 PRINTS PR00397 Sirohaem Fe-binding site signature 429 447 1.4E-9 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 SUPERFAMILY SSF56014 176 337 1.7E-46 T 28-03-2018 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 SUPERFAMILY SSF55124 25 175 1.21E-38 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD44_RS32845 8fdeb88179ddcf50d8f22b370498f39f 568 Gene3D G3DSA:3.30.413.10 426 568 3.7E-29 T 28-03-2018 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 SUPERFAMILY SSF54680 321 424 2.62E-26 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 Pfam PF00591 Glycosyl transferase family, a/b domain 77 287 9.3E-34 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 407 3.3E-168 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 PIRSF PIRSF000478 1 423 6.7E-151 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 Gene3D G3DSA:3.90.1170.30 325 412 1.2E-28 T 28-03-2018 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 66 1.4E-17 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 Gene3D G3DSA:1.20.970.10 1 66 1.0E-21 T 28-03-2018 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 SUPERFAMILY SSF52418 69 316 6.93E-81 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 Gene3D G3DSA:3.40.1030.10 68 324 4.0E-82 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 SMART SM00941 334 408 1.3E-34 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 335 407 1.4E-23 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS26795 09563e2172b7f2ca4c896266ce745e86 425 SUPERFAMILY SSF47648 1 69 1.44E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS24565 c51e753defd6bbdfc40b65c03a234c0c 299 SUPERFAMILY SSF53850 25 281 5.16E-73 T 28-03-2018 SMD44_RS24565 c51e753defd6bbdfc40b65c03a234c0c 299 Gene3D G3DSA:3.40.190.10 12 147 4.2E-17 T 28-03-2018 SMD44_RS24565 c51e753defd6bbdfc40b65c03a234c0c 299 Gene3D G3DSA:3.40.190.10 155 284 1.9E-29 T 28-03-2018 SMD44_RS24565 c51e753defd6bbdfc40b65c03a234c0c 299 Hamap MF_00995 Chorismate dehydratase [mqnA]. 26 288 30.569 T 28-03-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD44_RS24565 c51e753defd6bbdfc40b65c03a234c0c 299 Pfam PF02621 Menaquinone biosynthesis 26 282 2.1E-68 T 28-03-2018 IPR003773 Menaquinone biosynthesis enzyme SMD44_RS20375 576f0cac3fecef607272e8c6d254eda6 177 Pfam PF13302 Acetyltransferase (GNAT) domain 8 150 6.4E-27 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS20375 576f0cac3fecef607272e8c6d254eda6 177 SUPERFAMILY SSF55729 1 159 3.76E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS20375 576f0cac3fecef607272e8c6d254eda6 177 Gene3D G3DSA:3.40.630.30 1 171 4.4E-24 T 28-03-2018 SMD44_RS05810 a0555094999d377204b131b6d2990a3f 286 Pfam PF13560 Helix-turn-helix domain 12 73 4.8E-16 T 28-03-2018 SMD44_RS05810 a0555094999d377204b131b6d2990a3f 286 Gene3D G3DSA:1.10.3100.10 7 153 3.0E-14 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS05810 a0555094999d377204b131b6d2990a3f 286 SUPERFAMILY SSF47413 8 66 1.84E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS05810 a0555094999d377204b131b6d2990a3f 286 SMART SM00530 15 70 3.0E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS27060 dd8b9db9d79d5de77d1b0f0a87293f21 203 Gene3D G3DSA:3.90.1570.10 7 193 1.0E-22 T 28-03-2018 SMD44_RS27060 dd8b9db9d79d5de77d1b0f0a87293f21 203 SUPERFAMILY SSF52980 46 165 5.2E-15 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS27060 dd8b9db9d79d5de77d1b0f0a87293f21 203 Pfam PF05685 Putative restriction endonuclease 34 191 1.4E-17 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS03585 536c1f75b7237d4cf615c66a615f631f 433 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 207 304 4.9E-8 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMD44_RS03585 536c1f75b7237d4cf615c66a615f631f 433 Gene3D G3DSA:3.10.170.10 43 305 1.9E-20 T 28-03-2018 SMD44_RS03585 536c1f75b7237d4cf615c66a615f631f 433 SUPERFAMILY SSF55486 205 304 8.06E-10 T 28-03-2018 SMD44_RS34980 ffec7de9d742f27abd2fcc69c327a8b7 381 Pfam PF13378 Enolase C-terminal domain-like 129 354 3.6E-58 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS34980 ffec7de9d742f27abd2fcc69c327a8b7 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 3.6E-22 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMD44_RS34980 ffec7de9d742f27abd2fcc69c327a8b7 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMD44_RS34980 ffec7de9d742f27abd2fcc69c327a8b7 381 SUPERFAMILY SSF54826 1 112 9.07E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS34980 ffec7de9d742f27abd2fcc69c327a8b7 381 Gene3D G3DSA:3.30.390.10 1 108 1.6E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS34980 ffec7de9d742f27abd2fcc69c327a8b7 381 SMART SM00922 125 230 2.7E-17 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMD44_RS34980 ffec7de9d742f27abd2fcc69c327a8b7 381 Gene3D G3DSA:3.20.20.120 109 373 8.4E-62 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS34980 ffec7de9d742f27abd2fcc69c327a8b7 381 SUPERFAMILY SSF51604 95 358 1.41E-69 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS04795 8dbd49282384a4c4720904b9141e4cfc 323 Gene3D G3DSA:3.30.420.40 124 319 3.9E-53 T 28-03-2018 SMD44_RS04795 8dbd49282384a4c4720904b9141e4cfc 323 Pfam PF00480 ROK family 7 306 3.9E-61 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS04795 8dbd49282384a4c4720904b9141e4cfc 323 ProSitePatterns PS01125 ROK family signature. 138 165 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS04795 8dbd49282384a4c4720904b9141e4cfc 323 SUPERFAMILY SSF53067 6 309 2.69E-62 T 28-03-2018 SMD44_RS04795 8dbd49282384a4c4720904b9141e4cfc 323 Gene3D G3DSA:3.30.420.40 2 123 2.0E-27 T 28-03-2018 SMD44_RS17295 5a1a9845d95aad298ee38bca8bb3ecef 163 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 5 159 36.537 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 SMD44_RS17295 5a1a9845d95aad298ee38bca8bb3ecef 163 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 7 153 5.7E-63 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 SMD44_RS17295 5a1a9845d95aad298ee38bca8bb3ecef 163 Gene3D G3DSA:3.30.70.640 5 159 1.1E-66 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMD44_RS17295 5a1a9845d95aad298ee38bca8bb3ecef 163 Pfam PF01967 MoaC family 18 151 1.5E-52 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMD44_RS17295 5a1a9845d95aad298ee38bca8bb3ecef 163 SUPERFAMILY SSF55040 14 156 1.31E-57 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMD44_RS10875 18c0629d52b45d2f1b19965645707915 246 SUPERFAMILY SSF88697 5 221 2.49E-39 T 28-03-2018 IPR015947 PUA-like domain SMD44_RS10875 18c0629d52b45d2f1b19965645707915 246 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 221 1.7E-31 T 28-03-2018 IPR003111 Lon, substrate-binding domain SMD44_RS10875 18c0629d52b45d2f1b19965645707915 246 SMART SM00464 5 222 2.7E-48 T 28-03-2018 IPR003111 Lon, substrate-binding domain SMD44_RS10875 18c0629d52b45d2f1b19965645707915 246 Gene3D G3DSA:1.10.4060.10 141 229 7.0E-14 T 28-03-2018 SMD44_RS10875 18c0629d52b45d2f1b19965645707915 246 Gene3D G3DSA:2.30.130.40 1 139 9.3E-34 T 28-03-2018 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 385 397 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 Gene3D G3DSA:3.30.590.10 104 457 2.6E-125 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 SUPERFAMILY SSF55931 102 468 3.73E-137 T 28-03-2018 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 94 1.8E-23 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 2.5E-137 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 468 1.0E-199 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 Gene3D G3DSA:3.10.20.70 4 103 4.7E-26 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 SUPERFAMILY SSF54368 5 99 1.96E-29 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11630 7fb9bc3ab9243201fe646c8d633d500b 469 SMART SM01230 101 378 2.1E-151 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS38405 114d0410f9e57d11eb9a96a2e3297490 204 Gene3D G3DSA:3.40.50.1240 1 204 2.6E-54 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS38405 114d0410f9e57d11eb9a96a2e3297490 204 SUPERFAMILY SSF53254 2 201 7.62E-56 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS38405 114d0410f9e57d11eb9a96a2e3297490 204 PIRSF PIRSF000709 2 172 6.4E-12 T 28-03-2018 SMD44_RS38405 114d0410f9e57d11eb9a96a2e3297490 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 197 1.6E-56 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS38405 114d0410f9e57d11eb9a96a2e3297490 204 SMART SM00855 3 157 3.4E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS21555 96609cb0b7685a0f65cb17c645f65b3a 389 SUPERFAMILY SSF56801 73 326 7.06E-8 T 28-03-2018 SMD44_RS21555 96609cb0b7685a0f65cb17c645f65b3a 389 Gene3D G3DSA:3.40.50.980 84 294 3.1E-4 T 28-03-2018 SMD44_RS21555 96609cb0b7685a0f65cb17c645f65b3a 389 Pfam PF04443 Acyl-protein synthetase, LuxE 68 381 8.9E-22 T 28-03-2018 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 SMD44_RS11640 ab7d74158880ced6f0ceabc9d9dcf783 66 Pfam PF12728 Helix-turn-helix domain 9 57 1.1E-11 T 28-03-2018 SMD44_RS11640 ab7d74158880ced6f0ceabc9d9dcf783 66 SUPERFAMILY SSF46955 8 58 4.39E-9 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS11640 ab7d74158880ced6f0ceabc9d9dcf783 66 Gene3D G3DSA:1.10.10.10 9 65 6.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2727 3130 5.6E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 121 522 9.7E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1179 1573 2.9E-120 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.40.50.980 1307 1450 5.9E-27 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.40.50.980 250 406 3.3E-29 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.40.50.980 2858 3014 1.2E-29 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF47336 599 673 2.88E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1301 1312 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00501 AMP-binding enzyme 103 498 1.1E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00501 AMP-binding enzyme 2706 3106 9.3E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00501 AMP-binding enzyme 1158 1549 5.6E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF52777 2243 2425 1.56E-38 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF52777 2428 2674 4.78E-47 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:1.10.1200.10 3220 3291 4.3E-23 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:1.10.1200.10 1664 1732 1.0E-21 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF13193 AMP-binding enzyme C-terminal domain 3114 3191 1.8E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF13193 AMP-binding enzyme C-terminal domain 1557 1636 7.7E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF13193 AMP-binding enzyme C-terminal domain 506 582 1.6E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.40.50.1820 3292 3526 4.5E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF56801 2666 3228 1.96E-147 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.30.559.10 2234 2448 6.7E-37 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.30.559.10 671 898 9.1E-46 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.30.559.10 1745 1952 2.7E-22 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.40.50.980 2699 2857 1.3E-44 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.40.50.980 91 249 4.1E-48 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.40.50.980 1150 1306 7.6E-47 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3240 3255 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF52777 1741 1950 5.34E-26 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00668 Condensation domain 2246 2684 2.0E-78 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00668 Condensation domain 7 78 3.0E-7 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00668 Condensation domain 1767 2131 3.1E-35 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00668 Condensation domain 692 1137 2.4E-92 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.30.300.30 1544 1663 1.6E-36 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.30.300.30 493 612 1.0E-36 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:3.30.300.30 3101 3219 6.6E-39 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2852 2863 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SMART SM00823 Phosphopantetheine attachment site 607 676 1.1E-12 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SMART SM00823 Phosphopantetheine attachment site 3216 3285 3.4E-9 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SMART SM00823 Phosphopantetheine attachment site 1660 1728 7.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF52777 881 1145 1.33E-60 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SMART SM00824 Thioesterase 3317 3525 7.2E-5 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 ProSitePatterns PS00012 Phosphopantetheine attachment site. 631 646 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF56801 59 619 1.57E-149 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF52777 4 64 9.45E-9 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:2.30.38.10 3018 3099 2.1E-22 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:2.30.38.10 410 491 6.1E-22 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF53474 3288 3525 7.0E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1684 1699 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2074 2235 4.4E-37 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:1.10.1200.10 613 670 2.1E-25 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 244 255 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF47336 1652 1723 1.06E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Gene3D G3DSA:2.30.38.10 1451 1541 1.9E-19 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00975 Thioesterase domain 3308 3510 1.1E-22 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF47336 3208 3282 6.67E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF56801 1118 1673 3.53E-138 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00550 Phosphopantetheine attachment site 3219 3281 1.5E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00550 Phosphopantetheine attachment site 610 672 3.7E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 Pfam PF00550 Phosphopantetheine attachment site 1663 1723 5.5E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF52777 694 867 6.23E-49 T 28-03-2018 SMD44_RS38875 2e1d7e190d1859e58529bfa68f8290b1 3527 SUPERFAMILY SSF52777 1937 2212 1.78E-28 T 28-03-2018 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 Pfam PF00264 Common central domain of tyrosinase 30 228 3.7E-42 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 SUPERFAMILY SSF48056 1 272 3.27E-67 T 28-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 209 220 - T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 54 71 - T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 Gene3D G3DSA:1.10.1280.10 1 275 1.8E-77 T 28-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 PRINTS PR00092 Tyrosinase copper-binding domain signature 208 226 4.1E-20 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 PRINTS PR00092 Tyrosinase copper-binding domain signature 54 71 4.1E-20 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 PRINTS PR00092 Tyrosinase copper-binding domain signature 189 200 4.1E-20 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS15835 9e271c092ee253bfadc8e5e6c1c54a76 275 PRINTS PR00092 Tyrosinase copper-binding domain signature 83 88 4.1E-20 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS14400 c991ed675defb2a2edfe16ed6bfb41b0 343 Gene3D G3DSA:3.40.190.10 160 340 9.6E-28 T 28-03-2018 SMD44_RS14400 c991ed675defb2a2edfe16ed6bfb41b0 343 Pfam PF13379 NMT1-like family 53 280 1.7E-25 T 28-03-2018 SMD44_RS14400 c991ed675defb2a2edfe16ed6bfb41b0 343 Gene3D G3DSA:3.40.190.10 54 159 3.9E-13 T 28-03-2018 SMD44_RS14400 c991ed675defb2a2edfe16ed6bfb41b0 343 SMART SM00062 58 283 8.3E-5 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS14400 c991ed675defb2a2edfe16ed6bfb41b0 343 SUPERFAMILY SSF53850 55 276 3.63E-36 T 28-03-2018 SMD44_RS04110 04ba9fc6442613ee632d60c39d9f7577 140 SUPERFAMILY SSF46785 20 137 8.04E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04110 04ba9fc6442613ee632d60c39d9f7577 140 SMART SM00347 37 139 2.8E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS04110 04ba9fc6442613ee632d60c39d9f7577 140 Gene3D G3DSA:1.10.10.10 20 138 2.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04110 04ba9fc6442613ee632d60c39d9f7577 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 3.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS04110 04ba9fc6442613ee632d60c39d9f7577 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 3.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS04110 04ba9fc6442613ee632d60c39d9f7577 140 ProSitePatterns PS01117 MarR-type HTH domain signature. 81 116 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS04110 04ba9fc6442613ee632d60c39d9f7577 140 Pfam PF12802 MarR family 43 107 4.1E-11 T 28-03-2018 SMD44_RS06385 227b82e018ebeaecb70654eed410d8b8 938 SUPERFAMILY SSF53474 175 427 2.09E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06385 227b82e018ebeaecb70654eed410d8b8 938 Gene3D G3DSA:3.40.50.1820 168 492 3.7E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01345 fba00e0487f5d48133ad6f0b44e70829 270 SMART SM00530 12 84 5.5E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS01345 fba00e0487f5d48133ad6f0b44e70829 270 Gene3D G3DSA:1.10.260.40 2 89 1.2E-12 T 28-03-2018 SMD44_RS01345 fba00e0487f5d48133ad6f0b44e70829 270 SUPERFAMILY SSF47413 8 82 8.13E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS01345 fba00e0487f5d48133ad6f0b44e70829 270 Pfam PF13560 Helix-turn-helix domain 8 87 4.2E-10 T 28-03-2018 SMD44_RS27930 25dc432b4c9c27d323cfaf77041216d6 291 SUPERFAMILY SSF89550 2 80 5.1E-42 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD44_RS27930 25dc432b4c9c27d323cfaf77041216d6 291 SUPERFAMILY SSF89550 163 257 5.1E-42 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD44_RS27930 25dc432b4c9c27d323cfaf77041216d6 291 SMART SM00481 3 67 3.0E-12 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMD44_RS27930 25dc432b4c9c27d323cfaf77041216d6 291 Gene3D G3DSA:3.20.20.140 1 257 9.9E-45 T 28-03-2018 SMD44_RS27930 25dc432b4c9c27d323cfaf77041216d6 291 Pfam PF02811 PHP domain 4 95 2.8E-8 T 28-03-2018 IPR004013 PHP domain GO:0003824 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 Pfam PF00230 Major intrinsic protein 8 246 6.6E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 SUPERFAMILY SSF81338 8 249 5.63E-61 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 ProSitePatterns PS00221 MIP family signature. 66 74 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 TIGRFAM TIGR00861 MIP: MIP family channel proteins 11 246 2.7E-53 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 Gene3D G3DSA:1.20.1080.10 2 250 2.9E-75 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 PRINTS PR00783 Major intrinsic protein family signature 229 249 3.4E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 PRINTS PR00783 Major intrinsic protein family signature 150 168 3.4E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 PRINTS PR00783 Major intrinsic protein family signature 84 103 3.4E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 PRINTS PR00783 Major intrinsic protein family signature 6 25 3.4E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 PRINTS PR00783 Major intrinsic protein family signature 48 72 3.4E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS06715 d8ff438c74469003fd914da78daff2d1 250 PRINTS PR00783 Major intrinsic protein family signature 182 204 3.4E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 Gene3D G3DSA:3.90.180.10 241 326 7.9E-8 T 28-03-2018 SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 3.6E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 SUPERFAMILY SSF50129 1 140 4.11E-39 T 28-03-2018 IPR011032 GroES-like SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 SUPERFAMILY SSF51735 111 286 1.21E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 324 1.8E-141 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 Pfam PF00107 Zinc-binding dehydrogenase 151 266 4.8E-28 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 Gene3D G3DSA:3.40.50.720 149 240 2.8E-20 T 28-03-2018 SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 Gene3D G3DSA:3.90.180.10 1 148 9.9E-47 T 28-03-2018 SMD44_RS21760 9a9be8dfc4f99fad7becbd134c60feb4 331 SMART SM00829 10 323 2.1E-45 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS02620 e81411bd0035ccb3115f3f4636ce0821 502 Pfam PF00135 Carboxylesterase family 4 462 4.5E-88 T 28-03-2018 IPR002018 Carboxylesterase, type B SMD44_RS02620 e81411bd0035ccb3115f3f4636ce0821 502 SUPERFAMILY SSF53474 4 489 1.44E-106 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02620 e81411bd0035ccb3115f3f4636ce0821 502 Gene3D G3DSA:3.40.50.1820 2 496 1.6E-114 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02620 e81411bd0035ccb3115f3f4636ce0821 502 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 169 184 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site SMD44_RS24180 d00c562fd99e76109cd1e53c55d71830 243 Pfam PF14016 Protein of unknown function (DUF4232) 112 233 1.9E-21 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 SMD44_RS24180 d00c562fd99e76109cd1e53c55d71830 243 Gene3D G3DSA:3.40.190.10 3 242 9.4E-6 T 28-03-2018 SMD44_RS18805 02a53acd7964b941ba25f114f54cbda2 440 TIGRFAM TIGR00260 thrC: threonine synthase 81 412 3.5E-80 T 28-03-2018 IPR004450 Threonine synthase-like SMD44_RS18805 02a53acd7964b941ba25f114f54cbda2 440 Gene3D G3DSA:3.40.50.1100 116 224 2.2E-18 T 28-03-2018 SMD44_RS18805 02a53acd7964b941ba25f114f54cbda2 440 SUPERFAMILY SSF53686 27 423 2.1E-85 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS18805 02a53acd7964b941ba25f114f54cbda2 440 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 102 407 1.4E-61 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS18805 02a53acd7964b941ba25f114f54cbda2 440 Gene3D G3DSA:3.40.50.1100 226 424 6.9E-38 T 28-03-2018 SMD44_RS05980 e370cca9b69b4415ca0e20714711df16 285 SUPERFAMILY SSF55729 75 246 8.92E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS05980 e370cca9b69b4415ca0e20714711df16 285 Gene3D G3DSA:3.40.630.30 109 258 6.6E-14 T 28-03-2018 SMD44_RS05980 e370cca9b69b4415ca0e20714711df16 285 Pfam PF12746 GNAT acetyltransferase 34 245 8.0E-18 T 28-03-2018 IPR027365 GNAT acetyltransferase YdfB-like SMD44_RS20760 8e9e2ba8d68ac2eb154bc82fcb2575af 349 Pfam PF00005 ABC transporter 17 160 2.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS20760 8e9e2ba8d68ac2eb154bc82fcb2575af 349 Gene3D G3DSA:3.40.50.300 1 347 1.3E-56 T 28-03-2018 SMD44_RS20760 8e9e2ba8d68ac2eb154bc82fcb2575af 349 SUPERFAMILY SSF52540 7 210 2.41E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20760 8e9e2ba8d68ac2eb154bc82fcb2575af 349 SMART SM00382 25 208 4.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Gene3D G3DSA:3.40.50.300 7 298 1.6E-55 T 28-03-2018 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 SUPERFAMILY SSF54980 617 704 3.93E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 SMART SM00838 614 701 3.4E-58 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Pfam PF00679 Elongation factor G C-terminus 614 700 2.5E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 706 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 SUPERFAMILY SSF50447 276 416 3.28E-36 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Hamap MF_00054_B Elongation factor G [fusA]. 7 705 110.155 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 SUPERFAMILY SSF52540 7 293 1.43E-104 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Gene3D G3DSA:2.40.30.10 299 411 6.6E-32 T 28-03-2018 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Gene3D G3DSA:3.30.70.240 628 705 9.0E-32 T 28-03-2018 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 SUPERFAMILY SSF54980 416 493 5.4E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Gene3D G3DSA:3.30.230.10 505 627 5.3E-45 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Pfam PF03764 Elongation factor G, domain IV 491 612 8.6E-47 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 184 2.0E-33 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Pfam PF14492 Elongation Factor G, domain II 416 490 2.0E-33 T 28-03-2018 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Pfam PF00009 Elongation factor Tu GTP binding domain 10 293 3.0E-65 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 SMART SM00889 492 612 2.9E-69 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Pfam PF03144 Elongation factor Tu domain 2 336 403 4.5E-15 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 SUPERFAMILY SSF54211 491 613 7.08E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.2E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.2E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.2E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.2E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 PRINTS PR00315 GTP-binding elongation factor signature 59 67 4.2E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS25485 653003c2ffdfc2f19a3bd6aa934fbac8 708 Gene3D G3DSA:3.30.70.870 412 504 3.3E-37 T 28-03-2018 SMD44_RS43555 609c053e5271582cd62befc1146f9825 434 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 116 161 8.0E-5 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMD44_RS43555 609c053e5271582cd62befc1146f9825 434 Gene3D G3DSA:1.10.150.130 93 225 3.3E-13 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS43555 609c053e5271582cd62befc1146f9825 434 SUPERFAMILY SSF56349 104 413 5.59E-45 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS43555 609c053e5271582cd62befc1146f9825 434 Gene3D G3DSA:1.10.443.10 226 425 6.4E-32 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS43555 609c053e5271582cd62befc1146f9825 434 Pfam PF00589 Phage integrase family 239 409 2.4E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS24910 69166f80911ea0d2b4689e023ea32c13 148 Gene3D G3DSA:1.10.10.60 2 49 1.6E-10 T 28-03-2018 SMD44_RS42165 e945ca86a8ecd71cc9c71d8c8a9cac98 176 Pfam PF00668 Condensation domain 10 156 5.0E-28 T 28-03-2018 IPR001242 Condensation domain SMD44_RS42165 e945ca86a8ecd71cc9c71d8c8a9cac98 176 Gene3D G3DSA:3.30.559.10 1 120 3.5E-29 T 28-03-2018 SMD44_RS42165 e945ca86a8ecd71cc9c71d8c8a9cac98 176 SUPERFAMILY SSF52777 10 112 1.89E-25 T 28-03-2018 SMD44_RS42165 e945ca86a8ecd71cc9c71d8c8a9cac98 176 SUPERFAMILY SSF52777 99 159 7.11E-9 T 28-03-2018 SMD44_RS31395 38a6edbb446bc4299eddd128a783f370 408 SUPERFAMILY SSF50494 154 366 8.68E-16 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS31395 38a6edbb446bc4299eddd128a783f370 408 Gene3D G3DSA:2.40.10.10 296 405 6.7E-27 T 28-03-2018 SMD44_RS31395 38a6edbb446bc4299eddd128a783f370 408 Gene3D G3DSA:2.40.10.10 162 295 1.6E-12 T 28-03-2018 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 Gene3D G3DSA:2.40.110.10 130 228 2.7E-36 T 28-03-2018 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 SUPERFAMILY SSF56645 13 253 9.03E-68 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 Gene3D G3DSA:1.10.540.10 4 127 8.4E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 SUPERFAMILY SSF47203 238 390 8.83E-61 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 388 2.9E-52 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 PIRSF PIRSF016578 138 394 2.2E-13 T 28-03-2018 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 PIRSF PIRSF016578 5 130 0.0016 T 28-03-2018 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 228 1.3E-27 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 Gene3D G3DSA:1.20.140.10 229 393 1.1E-60 T 28-03-2018 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 133 145 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 126 4.1E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS06935 fff667f7a638d19c3fd5b0e94fbbce45 394 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 347 366 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS04860 b49cb2967d9e5fcf7e6885870a0847c0 149 SUPERFAMILY SSF52833 61 145 2.01E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS04860 b49cb2967d9e5fcf7e6885870a0847c0 149 Gene3D G3DSA:3.40.30.10 50 112 1.4E-9 T 28-03-2018 SMD44_RS04860 b49cb2967d9e5fcf7e6885870a0847c0 149 Pfam PF00085 Thioredoxin 63 142 3.7E-7 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMD44_RS04860 b49cb2967d9e5fcf7e6885870a0847c0 149 Gene3D G3DSA:3.40.30.10 113 149 0.015 T 28-03-2018 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 SUPERFAMILY SSF53901 523 659 1.15E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 SUPERFAMILY SSF53901 692 809 1.15E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 SUPERFAMILY SSF53901 164 225 3.59E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 SUPERFAMILY SSF53901 252 362 3.59E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 SUPERFAMILY SSF53901 28 101 3.59E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 SUPERFAMILY SSF53901 303 492 4.6E-6 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 Gene3D G3DSA:3.40.47.10 815 976 8.6E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 SMART SM00825 Beta-ketoacyl synthase 524 978 2.2E-56 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 Gene3D G3DSA:3.40.47.10 318 491 1.4E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 SUPERFAMILY SSF53901 774 975 5.47E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 Gene3D G3DSA:3.40.47.10 38 307 2.8E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 Gene3D G3DSA:3.40.47.10 514 813 1.1E-50 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 811 922 1.5E-32 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 523 802 2.8E-49 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36265 76de5cd8b7e9e9b8d330b154d653aef6 984 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 51 230 6.8E-22 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 Gene3D G3DSA:3.40.1160.10 1 300 5.1E-74 T 28-03-2018 SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 PRINTS PR00474 Glutamate 5-kinase family signature 59 73 7.0E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 PRINTS PR00474 Glutamate 5-kinase family signature 246 266 7.0E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 PRINTS PR00474 Glutamate 5-kinase family signature 195 222 7.0E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 PIRSF PIRSF000728 13 296 1.7E-97 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 270 2.1E-71 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 Hamap MF_00082_B Acetylglutamate kinase [argB]. 26 296 34.382 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 SUPERFAMILY SSF53633 7 297 3.53E-87 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMD44_RS07795 cc39283a549d4cbc7fc65c179af2999d 302 Pfam PF00696 Amino acid kinase family 28 273 2.8E-49 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 SMART SM00344 3 109 3.9E-25 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 Gene3D G3DSA:3.30.70.920 71 149 2.4E-18 T 28-03-2018 SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 SUPERFAMILY SSF46785 2 63 2.72E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 SUPERFAMILY SSF54909 63 148 3.62E-16 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 8.5E-13 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 1.0E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 Gene3D G3DSA:1.10.10.10 1 70 2.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.8E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.8E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS15755 30bfe27ccd83487a6591c1bf0606f38a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.8E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS09200 6b934c4fd139c783385d773691c96b0e 340 Pfam PF01497 Periplasmic binding protein 80 310 3.8E-14 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS09200 6b934c4fd139c783385d773691c96b0e 340 Gene3D G3DSA:3.40.50.1980 34 173 9.3E-13 T 28-03-2018 SMD44_RS09200 6b934c4fd139c783385d773691c96b0e 340 Gene3D G3DSA:3.40.50.1980 174 338 1.4E-18 T 28-03-2018 SMD44_RS09200 6b934c4fd139c783385d773691c96b0e 340 SUPERFAMILY SSF53807 45 333 3.92E-25 T 28-03-2018 SMD44_RS25390 a1ad959d8e51edc3d1091094a4a1793e 339 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 277 283 - T 28-03-2018 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 SMD44_RS25390 a1ad959d8e51edc3d1091094a4a1793e 339 SUPERFAMILY SSF51556 7 336 5.11E-68 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS25390 a1ad959d8e51edc3d1091094a4a1793e 339 Pfam PF00962 Adenosine/AMP deaminase 10 330 2.6E-94 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMD44_RS25390 a1ad959d8e51edc3d1091094a4a1793e 339 Gene3D G3DSA:3.20.20.140 1 339 1.0E-75 T 28-03-2018 SMD44_RS25390 a1ad959d8e51edc3d1091094a4a1793e 339 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 333 6.2E-116 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 Gene3D G3DSA:3.60.20.10 28 444 1.9E-171 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 Pfam PF01493 GXGXG motif 1268 1445 3.0E-76 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 Gene3D G3DSA:3.20.20.70 445 798 2.0E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 SUPERFAMILY SSF56235 28 438 1.67E-147 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 Pfam PF00310 Glutamine amidotransferases class-II 28 436 3.0E-181 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 Pfam PF01645 Conserved region in glutamate synthase 820 1183 1.7E-155 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 Gene3D G3DSA:2.160.20.60 1238 1514 2.6E-108 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 SUPERFAMILY SSF69336 1232 1497 1.83E-88 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 Pfam PF04898 Glutamate synthase central domain 462 754 7.3E-112 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 SUPERFAMILY SSF51395 451 1220 1.1E-260 T 28-03-2018 SMD44_RS10710 fcbde414ec0057f491b844cb0fba9a5b 1524 Gene3D G3DSA:3.20.20.70 799 1235 3.4E-159 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 SUPERFAMILY SSF52540 1073 1250 3.56E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 SUPERFAMILY SSF52540 761 1024 2.55E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 Gene3D G3DSA:3.40.50.300 1051 1279 7.9E-8 T 28-03-2018 SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 Gene3D G3DSA:3.40.50.300 796 1016 3.6E-11 T 28-03-2018 SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 Gene3D G3DSA:3.40.50.300 384 653 7.3E-19 T 28-03-2018 SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 690 2.6E-262 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 SMART SM00382 824 1002 0.21 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 SMART SM00382 467 646 0.52 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 SMART SM00382 1112 1275 5.4 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 SUPERFAMILY SSF52540 431 655 2.43E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 Pfam PF01580 FtsK/SpoIIIE family 806 1035 3.2E-46 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 Pfam PF01580 FtsK/SpoIIIE family 432 558 1.6E-24 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS31020 1edf77ce54d61c07b7e0696971c383ff 1322 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 743 1315 1.0E-233 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria SMD44_RS11280 788d8eb4b325ca4d6d40ccb74e55c2a2 258 Gene3D G3DSA:3.60.21.10 2 257 1.6E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS11280 788d8eb4b325ca4d6d40ccb74e55c2a2 258 SUPERFAMILY SSF56300 86 249 3.67E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS11280 788d8eb4b325ca4d6d40ccb74e55c2a2 258 SUPERFAMILY SSF56300 4 44 3.67E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS11280 788d8eb4b325ca4d6d40ccb74e55c2a2 258 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 5 247 9.0E-9 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 455 6.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 441 6.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 6.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 6.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 SUPERFAMILY SSF55874 338 499 8.51E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 SUPERFAMILY SSF47384 266 347 8.24E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 SMART SM00304 219 273 3.3E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 Gene3D G3DSA:1.10.287.130 264 344 7.0E-18 T 28-03-2018 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 Pfam PF00512 His Kinase A (phospho-acceptor) domain 282 347 2.0E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 Gene3D G3DSA:3.30.565.10 351 504 4.4E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 496 9.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 SMART SM00387 390 497 1.5E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26485 d4897a21a5d446fa6d9a7b4c1d1af8db 528 SMART SM00388 281 348 1.3E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 SUPERFAMILY SSF74650 415 733 1.47E-37 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 Gene3D G3DSA:1.50.10.100 33 409 1.5E-88 T 28-03-2018 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 SUPERFAMILY SSF48230 406 434 7.02E-60 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 SUPERFAMILY SSF48230 38 375 7.02E-60 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 729 796 1.6E-14 T 28-03-2018 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 Gene3D G3DSA:2.70.98.10 412 727 2.0E-65 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 Gene3D G3DSA:2.60.220.10 728 842 8.3E-27 T 28-03-2018 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 416 715 2.9E-62 T 28-03-2018 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 49 369 3.5E-58 T 28-03-2018 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical SMD44_RS39860 6b4f0205018194c76df02cd2a454bc6b 845 SUPERFAMILY SSF49863 727 842 2.35E-20 T 28-03-2018 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 SMD44_RS34705 841224e49a3363e01be1b7d5070a6d6a 393 Gene3D G3DSA:1.10.10.10 5 68 4.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34705 841224e49a3363e01be1b7d5070a6d6a 393 SUPERFAMILY SSF46785 8 69 1.72E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34705 841224e49a3363e01be1b7d5070a6d6a 393 Gene3D G3DSA:3.30.420.40 69 194 5.1E-31 T 28-03-2018 SMD44_RS34705 841224e49a3363e01be1b7d5070a6d6a 393 SUPERFAMILY SSF53067 77 389 2.13E-60 T 28-03-2018 SMD44_RS34705 841224e49a3363e01be1b7d5070a6d6a 393 Pfam PF00480 ROK family 78 386 8.8E-60 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS34705 841224e49a3363e01be1b7d5070a6d6a 393 Gene3D G3DSA:3.30.420.40 195 392 8.5E-57 T 28-03-2018 SMD44_RS34705 841224e49a3363e01be1b7d5070a6d6a 393 ProSitePatterns PS01125 ROK family signature. 209 236 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 Pfam PF00990 Diguanylate cyclase, GGDEF domain 534 695 4.9E-40 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 Gene3D G3DSA:3.20.20.450 709 966 3.0E-74 T 28-03-2018 IPR001633 EAL domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 SMART SM00091 411 477 8.0E-9 T 28-03-2018 IPR000014 PAS domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 530 699 3.4E-39 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 408 530 7.3E-13 T 28-03-2018 IPR000014 PAS domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 Gene3D G3DSA:3.30.70.270 537 708 1.8E-58 T 28-03-2018 SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 Pfam PF08448 PAS fold 420 525 1.1E-6 T 28-03-2018 IPR013656 PAS fold-4 SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 Gene3D G3DSA:3.30.450.20 390 536 3.1E-23 T 28-03-2018 SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 Pfam PF00563 EAL domain 717 951 1.6E-48 T 28-03-2018 IPR001633 EAL domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 SUPERFAMILY SSF141868 717 957 6.28E-52 T 28-03-2018 IPR001633 EAL domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 SMART SM00052 710 956 2.0E-45 T 28-03-2018 IPR001633 EAL domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 SUPERFAMILY SSF55785 403 521 5.03E-16 T 28-03-2018 IPR000014 PAS domain SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 SUPERFAMILY SSF55073 539 701 8.63E-43 T 28-03-2018 IPR029787 Nucleotide cyclase SMD44_RS29900 4c80e24af5dc45bc29bbcf8658874177 1042 SMART SM00267 523 700 7.5E-54 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 Gene3D G3DSA:3.40.50.970 7 294 2.6E-69 T 28-03-2018 SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 SUPERFAMILY SSF52518 2 345 7.32E-72 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 Pfam PF02779 Transketolase, pyrimidine binding domain 315 477 3.3E-35 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 SMART SM00861 315 479 1.8E-48 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 SUPERFAMILY SSF52922 499 619 1.31E-27 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 7.9E-109 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 SUPERFAMILY SSF52518 294 477 4.82E-50 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 Gene3D G3DSA:3.40.50.920 488 626 4.6E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 617 5.7E-193 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 Gene3D G3DSA:3.40.50.970 295 482 3.0E-47 T 28-03-2018 SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 621 41.899 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 Pfam PF02780 Transketolase, C-terminal domain 499 612 7.0E-30 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS32310 88cadaf533d9b6bb1c04ebfe7c5f4301 642 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS06415 19792e271542db6b856054a0f33a9400 160 SUPERFAMILY SSF54427 2 150 2.2E-25 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS06415 19792e271542db6b856054a0f33a9400 160 Gene3D G3DSA:3.10.450.50 1 152 2.6E-33 T 28-03-2018 SMD44_RS06415 19792e271542db6b856054a0f33a9400 160 Pfam PF13577 SnoaL-like domain 9 143 8.2E-22 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 SUPERFAMILY SSF56601 60 312 8.21E-70 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 PRINTS PR00118 Beta-lactamase class A signature 131 156 9.2E-63 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 PRINTS PR00118 Beta-lactamase class A signature 193 218 9.2E-63 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 PRINTS PR00118 Beta-lactamase class A signature 60 84 9.2E-63 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 PRINTS PR00118 Beta-lactamase class A signature 167 191 9.2E-63 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 PRINTS PR00118 Beta-lactamase class A signature 246 261 9.2E-63 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 PRINTS PR00118 Beta-lactamase class A signature 229 244 9.2E-63 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 PRINTS PR00118 Beta-lactamase class A signature 91 108 9.2E-63 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 Pfam PF13354 Beta-lactamase enzyme family 81 278 2.4E-34 T 28-03-2018 SMD44_RS29615 9479fe0bc6718d40c0dae0e687872275 320 Gene3D G3DSA:3.40.710.10 58 313 3.1E-32 T 28-03-2018 SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 SUPERFAMILY SSF52540 385 537 7.39E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 Gene3D G3DSA:3.40.50.300 370 538 2.1E-34 T 28-03-2018 SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 SUPERFAMILY SSF52540 149 252 2.8E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 SUPERFAMILY SSF52540 21 116 2.8E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 SMART SM00382 390 550 2.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 SMART SM00382 50 255 2.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 Gene3D G3DSA:3.40.50.300 13 302 3.6E-46 T 28-03-2018 SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 Pfam PF00005 ABC transporter 385 506 2.4E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 Pfam PF00005 ABC transporter 41 210 3.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19325 a81ed29436c4f045df73111cb82323d0 560 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS42545 7cabad72f98c671db7d74bf07fe41514 423 SMART SM01209 114 295 4.5E-8 T 28-03-2018 SMD44_RS42545 7cabad72f98c671db7d74bf07fe41514 423 Gene3D G3DSA:3.40.50.20 9 118 2.2E-12 T 28-03-2018 SMD44_RS42545 7cabad72f98c671db7d74bf07fe41514 423 SUPERFAMILY SSF56059 107 327 3.36E-39 T 28-03-2018 SMD44_RS42545 7cabad72f98c671db7d74bf07fe41514 423 Gene3D G3DSA:3.30.470.20 119 406 7.5E-52 T 28-03-2018 SMD44_RS42545 7cabad72f98c671db7d74bf07fe41514 423 Pfam PF13535 ATP-grasp domain 152 298 5.9E-21 T 28-03-2018 SMD44_RS33750 f1325ba13f83d0ed03a16aa6a94e0ab0 116 Gene3D G3DSA:1.10.10.10 38 91 6.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33750 f1325ba13f83d0ed03a16aa6a94e0ab0 116 SUPERFAMILY SSF52172 26 89 1.19E-7 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS33750 f1325ba13f83d0ed03a16aa6a94e0ab0 116 Pfam PF03861 ANTAR domain 37 89 8.4E-17 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS33750 f1325ba13f83d0ed03a16aa6a94e0ab0 116 PIRSF PIRSF010636 22 116 3.1E-33 T 28-03-2018 IPR024189 ANTAR transcription anti-termination regulator SMD44_RS33750 f1325ba13f83d0ed03a16aa6a94e0ab0 116 SMART SM01012 34 89 2.6E-18 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS30380 3f5f25d6a9a118305ec7b0106aba5b98 419 SUPERFAMILY SSF55797 298 417 1.31E-23 T 28-03-2018 IPR014044 CAP domain SMD44_RS30380 3f5f25d6a9a118305ec7b0106aba5b98 419 Pfam PF00188 Cysteine-rich secretory protein family 303 417 3.8E-21 T 28-03-2018 IPR014044 CAP domain SMD44_RS30380 3f5f25d6a9a118305ec7b0106aba5b98 419 Gene3D G3DSA:3.40.33.10 291 415 7.0E-17 T 28-03-2018 IPR014044 CAP domain SMD44_RS23790 b9af79451206eeb725d7ca2006d0c081 317 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 36 240 4.0E-12 T 28-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 SMD44_RS23790 b9af79451206eeb725d7ca2006d0c081 317 SUPERFAMILY SSF53335 1 304 1.14E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS11200 e137e6ddc8d52474728988d1aeb460b5 450 Pfam PF01474 Class-II DAHP synthetase family 13 444 4.5E-202 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD44_RS11200 e137e6ddc8d52474728988d1aeb460b5 450 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 11 450 1.6E-238 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD44_RS11200 e137e6ddc8d52474728988d1aeb460b5 450 Gene3D G3DSA:3.20.20.70 210 396 1.5E-7 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS11200 e137e6ddc8d52474728988d1aeb460b5 450 SUPERFAMILY SSF51569 11 448 1.68E-198 T 28-03-2018 SMD44_RS02125 5b27760c94ff4551421229dae372dff4 154 Pfam PF13474 SnoaL-like domain 34 137 2.6E-7 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS02125 5b27760c94ff4551421229dae372dff4 154 Gene3D G3DSA:3.10.450.50 1 146 4.0E-11 T 28-03-2018 SMD44_RS02125 5b27760c94ff4551421229dae372dff4 154 SUPERFAMILY SSF54427 33 136 2.68E-8 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS13865 f4aa15854c07a296ebb7e709529e2db7 843 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 278 454 6.4E-13 T 28-03-2018 IPR004477 ComEC/Rec2-related protein SMD44_RS13865 f4aa15854c07a296ebb7e709529e2db7 843 Pfam PF03772 Competence protein 256 532 3.9E-42 T 28-03-2018 IPR004477 ComEC/Rec2-related protein SMD44_RS13865 f4aa15854c07a296ebb7e709529e2db7 843 SMART SM00849 579 776 4.6E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS13865 f4aa15854c07a296ebb7e709529e2db7 843 Pfam PF00753 Metallo-beta-lactamase superfamily 577 648 1.5E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS13865 f4aa15854c07a296ebb7e709529e2db7 843 SUPERFAMILY SSF56281 565 809 3.41E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS13865 f4aa15854c07a296ebb7e709529e2db7 843 Gene3D G3DSA:3.60.15.10 567 800 2.2E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS37910 baaa576630428cc859218e2b991fd654 543 SUPERFAMILY SSF56801 7 534 2.35E-109 T 28-03-2018 SMD44_RS37910 baaa576630428cc859218e2b991fd654 543 Gene3D G3DSA:3.40.50.980 183 344 4.3E-31 T 28-03-2018 SMD44_RS37910 baaa576630428cc859218e2b991fd654 543 Pfam PF00501 AMP-binding enzyme 27 439 1.6E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS37910 baaa576630428cc859218e2b991fd654 543 Gene3D G3DSA:3.40.50.980 11 182 8.9E-29 T 28-03-2018 SMD44_RS37910 baaa576630428cc859218e2b991fd654 543 Gene3D G3DSA:2.30.38.10 345 432 1.2E-24 T 28-03-2018 SMD44_RS37910 baaa576630428cc859218e2b991fd654 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 525 6.5E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS37910 baaa576630428cc859218e2b991fd654 543 Gene3D G3DSA:3.30.300.30 433 541 5.4E-16 T 28-03-2018 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Gene3D G3DSA:1.10.3260.10 61 175 2.9E-20 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Gene3D G3DSA:1.10.3260.10 1 60 0.0026 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Gene3D G3DSA:3.30.1490.70 326 384 1.3E-15 T 28-03-2018 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 SUPERFAMILY SSF50249 387 508 2.23E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Hamap MF_00407 DNA ligase [lig]. 1 511 26.603 T 28-03-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 68 507 1.6E-78 T 28-03-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 SUPERFAMILY SSF56091 180 385 1.25E-46 T 28-03-2018 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Gene3D G3DSA:2.40.50.140 385 511 7.2E-32 T 28-03-2018 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Pfam PF01068 ATP dependent DNA ligase domain 186 385 2.1E-43 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 208 216 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Gene3D G3DSA:3.30.470.30 176 325 2.6E-34 T 28-03-2018 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 SUPERFAMILY SSF117018 2 202 9.68E-31 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Pfam PF04679 ATP dependent DNA ligase C terminal region 404 495 1.4E-14 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SMD44_RS03065 2fef595edd03aaa6df96eeef67bcdcdd 512 Pfam PF04675 DNA ligase N terminus 67 135 7.1E-7 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMD44_RS21960 a880b4a85e620043c6d741e196a5c82e 289 Gene3D G3DSA:3.40.50.720 1 158 4.4E-27 T 28-03-2018 SMD44_RS21960 a880b4a85e620043c6d741e196a5c82e 289 PIRSF PIRSF000103 1 289 8.5E-40 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS21960 a880b4a85e620043c6d741e196a5c82e 289 SUPERFAMILY SSF51735 4 155 2.23E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21960 a880b4a85e620043c6d741e196a5c82e 289 Gene3D G3DSA:1.10.1040.10 159 289 7.8E-15 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS21960 a880b4a85e620043c6d741e196a5c82e 289 SUPERFAMILY SSF48179 162 287 6.91E-6 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS21960 a880b4a85e620043c6d741e196a5c82e 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 154 1.4E-20 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 15 616 52.23 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 280 288 - T 28-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 SUPERFAMILY SSF53795 256 615 1.08E-159 T 28-03-2018 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 PIRSF PIRSF001348 9 616 1.3E-277 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 256 615 9.8E-173 T 28-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 SUPERFAMILY SSF68923 17 255 6.28E-97 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 Gene3D G3DSA:3.90.228.20 256 327 9.4E-22 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 Gene3D G3DSA:3.90.228.20 335 616 7.4E-127 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 27 252 6.1E-100 T 28-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD44_RS27200 f5795c4537f1e24d7d9a44506f8ba3ce 616 Gene3D G3DSA:3.40.449.10 11 255 5.6E-115 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 SUPERFAMILY SSF53067 3 190 1.91E-47 T 28-03-2018 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 Gene3D G3DSA:2.60.34.10 429 603 1.1E-14 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 6 13 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 199 212 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 Gene3D G3DSA:3.30.420.40 203 371 4.6E-33 T 28-03-2018 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 PRINTS PR00301 70kDa heat shock protein signature 144 164 9.5E-32 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 PRINTS PR00301 70kDa heat shock protein signature 374 394 9.5E-32 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 PRINTS PR00301 70kDa heat shock protein signature 2 15 9.5E-32 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 PRINTS PR00301 70kDa heat shock protein signature 342 358 9.5E-32 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 PRINTS PR00301 70kDa heat shock protein signature 32 44 9.5E-32 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 PRINTS PR00301 70kDa heat shock protein signature 205 215 9.5E-32 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 SUPERFAMILY SSF53067 195 390 4.68E-47 T 28-03-2018 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 Pfam PF00012 Hsp70 protein 3 393 3.1E-107 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 SUPERFAMILY SSF100920 430 540 1.12E-11 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMD44_RS32580 2b150fc4dbf05383912d6e73b606732b 713 Gene3D G3DSA:3.30.420.40 1 202 4.2E-59 T 28-03-2018 SMD44_RS05195 87230d393a4f5ccb3fa2362378e40a3a 743 SUPERFAMILY SSF82866 466 699 9.42E-28 T 28-03-2018 SMD44_RS05195 87230d393a4f5ccb3fa2362378e40a3a 743 Gene3D G3DSA:1.20.1640.10 455 696 1.2E-31 T 28-03-2018 SMD44_RS05195 87230d393a4f5ccb3fa2362378e40a3a 743 Gene3D G3DSA:1.20.1640.10 121 344 1.5E-34 T 28-03-2018 SMD44_RS05195 87230d393a4f5ccb3fa2362378e40a3a 743 Pfam PF03176 MMPL family 45 371 9.5E-83 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS05195 87230d393a4f5ccb3fa2362378e40a3a 743 Pfam PF03176 MMPL family 441 700 8.4E-34 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS05195 87230d393a4f5ccb3fa2362378e40a3a 743 SUPERFAMILY SSF82866 126 334 6.41E-33 T 28-03-2018 SMD44_RS31360 f806f5a65a2bebfd2df777d8c88e4407 312 Gene3D G3DSA:3.40.50.300 7 197 9.1E-60 T 28-03-2018 SMD44_RS31360 f806f5a65a2bebfd2df777d8c88e4407 312 Gene3D G3DSA:1.10.287.890 200 281 3.3E-20 T 28-03-2018 SMD44_RS31360 f806f5a65a2bebfd2df777d8c88e4407 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 311 27.421 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMD44_RS31360 f806f5a65a2bebfd2df777d8c88e4407 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 3.8E-75 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMD44_RS31360 f806f5a65a2bebfd2df777d8c88e4407 312 Pfam PF01715 IPP transferase 43 285 4.5E-73 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMD44_RS31360 f806f5a65a2bebfd2df777d8c88e4407 312 SUPERFAMILY SSF52540 10 152 8.6E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 SUPERFAMILY SSF51735 1 143 7.24E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 5.6E-27 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 4.7E-102 T 28-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 4.8E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 4.8E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 4.8E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 4.8E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 4.8E-37 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 1.0E-36 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 SMART SM01350 160 293 2.1E-6 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 Gene3D G3DSA:3.40.50.720 2 161 1.0E-33 T 28-03-2018 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 PIRSF PIRSF000103 1 288 1.4E-25 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 Gene3D G3DSA:1.10.1040.10 162 293 3.0E-40 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS21135 c3bc150b99a6d70bf512ce063ed94c1e 294 SUPERFAMILY SSF48179 158 291 2.38E-42 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 SUPERFAMILY SSF46785 10 56 4.57E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 Pfam PF01037 Lrp/AsnC ligand binding domain 247 316 4.1E-8 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 Gene3D G3DSA:1.10.10.10 10 61 4.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 Gene3D G3DSA:3.30.70.920 234 325 6.6E-14 T 28-03-2018 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 Gene3D G3DSA:3.30.70.920 62 147 0.0044 T 28-03-2018 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 Gene3D G3DSA:1.10.10.10 176 232 5.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 SUPERFAMILY SSF46785 185 231 6.45E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 Pfam PF13404 AsnC-type helix-turn-helix domain 10 49 6.4E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 Pfam PF13404 AsnC-type helix-turn-helix domain 185 221 1.2E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 8.5E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 8.5E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 8.5E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 SUPERFAMILY SSF54909 240 319 4.69E-11 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 SMART SM00344 185 286 1.6E-5 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS34605 9950fe2db671bb4afaab081468c29476 327 SMART SM00344 9 113 0.0011 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 Pfam PF07731 Multicopper oxidase 444 554 2.4E-26 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 Gene3D G3DSA:2.60.40.420 416 554 3.7E-37 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 Pfam PF07732 Multicopper oxidase 101 205 1.9E-33 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 SUPERFAMILY SSF49503 285 417 9.72E-30 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 SUPERFAMILY SSF49503 207 250 9.72E-30 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 ProSitePatterns PS00079 Multicopper oxidases signature 1. 534 554 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 SUPERFAMILY SSF49503 436 553 5.73E-34 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 ProSitePatterns PS00080 Multicopper oxidases signature 2. 539 550 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 Gene3D G3DSA:2.60.40.420 206 415 1.1E-40 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 SUPERFAMILY SSF49503 80 228 1.22E-34 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 Gene3D G3DSA:2.60.40.420 63 205 3.0E-30 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11940 798a0484b127cf9fe041f089c08937e9 558 Pfam PF00394 Multicopper oxidase 213 407 3.2E-21 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 SMD44_RS13740 7ad65ff79abf8eec3b5ce1eb2cb6f30f 165 Gene3D G3DSA:3.40.390.30 1 153 1.7E-41 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 SMD44_RS13740 7ad65ff79abf8eec3b5ce1eb2cb6f30f 165 SUPERFAMILY SSF55486 3 149 6.1E-37 T 28-03-2018 SMD44_RS13740 7ad65ff79abf8eec3b5ce1eb2cb6f30f 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 21.332 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMD44_RS13740 7ad65ff79abf8eec3b5ce1eb2cb6f30f 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site SMD44_RS13740 7ad65ff79abf8eec3b5ce1eb2cb6f30f 165 Pfam PF02130 Uncharacterized protein family UPF0054 16 147 1.4E-35 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMD44_RS13740 7ad65ff79abf8eec3b5ce1eb2cb6f30f 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 6.6E-31 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMD44_RS29065 1ad741e14c33cc1fe7722e828c45bf83 216 Gene3D G3DSA:3.60.160.10 2 216 3.7E-49 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS29065 1ad741e14c33cc1fe7722e828c45bf83 216 Pfam PF01987 Mitochondrial biogenesis AIM24 7 211 1.2E-35 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS29065 1ad741e14c33cc1fe7722e828c45bf83 216 SUPERFAMILY SSF51219 5 213 2.07E-46 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD44_RS27715 b55a0923a7f5d96b24f4cbca1a1102e3 542 SUPERFAMILY SSF53850 36 536 2.58E-94 T 28-03-2018 SMD44_RS27715 b55a0923a7f5d96b24f4cbca1a1102e3 542 Gene3D G3DSA:3.40.190.10 180 312 5.9E-32 T 28-03-2018 SMD44_RS27715 b55a0923a7f5d96b24f4cbca1a1102e3 542 PIRSF PIRSF002741 9 539 3.1E-65 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS27715 b55a0923a7f5d96b24f4cbca1a1102e3 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 461 5.8E-52 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS27715 b55a0923a7f5d96b24f4cbca1a1102e3 542 Gene3D G3DSA:3.90.76.10 68 179 3.5E-26 T 28-03-2018 SMD44_RS27715 b55a0923a7f5d96b24f4cbca1a1102e3 542 Gene3D G3DSA:3.10.105.10 313 514 1.9E-35 T 28-03-2018 SMD44_RS26170 5c059fb48dd7ca4670bfa9241f76c1df 384 SUPERFAMILY SSF52540 55 284 3.6E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS26170 5c059fb48dd7ca4670bfa9241f76c1df 384 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 52 324 1.1E-109 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMD44_RS26170 5c059fb48dd7ca4670bfa9241f76c1df 384 Pfam PF00005 ABC transporter 60 207 1.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS26170 5c059fb48dd7ca4670bfa9241f76c1df 384 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS26170 5c059fb48dd7ca4670bfa9241f76c1df 384 SMART SM00382 68 265 1.4E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS26170 5c059fb48dd7ca4670bfa9241f76c1df 384 Gene3D G3DSA:3.40.50.300 16 326 6.5E-78 T 28-03-2018 SMD44_RS11970 cc155d824b55d608fecd981f5e36cadd 293 PIRSF PIRSF000388 25 293 1.6E-107 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMD44_RS11970 cc155d824b55d608fecd981f5e36cadd 293 Gene3D G3DSA:3.20.20.60 17 292 2.5E-82 T 28-03-2018 SMD44_RS11970 cc155d824b55d608fecd981f5e36cadd 293 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 36 293 5.8E-92 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMD44_RS11970 cc155d824b55d608fecd981f5e36cadd 293 SUPERFAMILY SSF51621 31 291 2.32E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS11970 cc155d824b55d608fecd981f5e36cadd 293 Pfam PF02548 Ketopantoate hydroxymethyltransferase 31 287 5.4E-106 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMD44_RS11970 cc155d824b55d608fecd981f5e36cadd 293 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 32 292 41.853 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 SUPERFAMILY SSF69304 548 656 5.62E-19 T 28-03-2018 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 SUPERFAMILY SSF69304 375 501 5.62E-19 T 28-03-2018 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Pfam PF03572 Peptidase family S41 881 1035 9.7E-22 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 SUPERFAMILY SSF69304 10 265 1.57E-33 T 28-03-2018 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Gene3D G3DSA:2.130.10.10 254 669 5.1E-51 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Pfam PF07676 WD40-like Beta Propeller Repeat 46 69 4.2E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Pfam PF07676 WD40-like Beta Propeller Repeat 474 497 0.2 T 28-03-2018 IPR011659 WD40-like Beta Propeller SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Pfam PF14684 Tricorn protease C1 domain 684 751 4.0E-30 T 28-03-2018 IPR028204 Tricorn protease C1 domain SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 PIRSF PIRSF036421 1 1069 0.0 T 28-03-2018 IPR012393 Tricorn protease GO:0008236 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 SMART SM00245 831 1036 1.4E-18 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Gene3D G3DSA:3.30.750.44 684 751 5.2E-23 T 28-03-2018 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Gene3D G3DSA:2.30.42.10 760 857 3.5E-10 T 28-03-2018 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Gene3D G3DSA:2.120.10.60 6 253 2.1E-31 T 28-03-2018 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Gene3D G3DSA:3.90.226.10 858 1070 9.8E-30 T 28-03-2018 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 SUPERFAMILY SSF52096 681 760 1.08E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 SUPERFAMILY SSF52096 853 1061 1.08E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 SUPERFAMILY SSF50156 762 844 8.99E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS13770 70530ff919edc218b00bf6b11c43e06c 1080 Pfam PF14685 Tricorn protease PDZ domain 762 851 5.9E-28 T 28-03-2018 IPR029414 Tricorn protease, PDZ domain SMD44_RS18490 92d31c39de360442a6a63cbb98374bbc 170 Gene3D G3DSA:1.20.5.810 8 40 1.4E-8 T 28-03-2018 SMD44_RS18490 92d31c39de360442a6a63cbb98374bbc 170 Gene3D G3DSA:1.20.1290.10 41 170 2.8E-23 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS18490 92d31c39de360442a6a63cbb98374bbc 170 Pfam PF02627 Carboxymuconolactone decarboxylase family 48 118 8.5E-7 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS18490 92d31c39de360442a6a63cbb98374bbc 170 SUPERFAMILY SSF69118 2 168 3.99E-42 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS28390 d6ed97c887731ebb87c093688cd96768 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.6E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28390 d6ed97c887731ebb87c093688cd96768 198 SUPERFAMILY SSF46689 3 86 2.34E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS28390 d6ed97c887731ebb87c093688cd96768 198 Gene3D G3DSA:1.10.10.60 1 38 1.4E-12 T 28-03-2018 SMD44_RS28390 d6ed97c887731ebb87c093688cd96768 198 SUPERFAMILY SSF48498 83 196 4.73E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS28390 d6ed97c887731ebb87c093688cd96768 198 Gene3D G3DSA:1.10.260.40 39 88 5.7E-8 T 28-03-2018 SMD44_RS28390 d6ed97c887731ebb87c093688cd96768 198 Gene3D G3DSA:1.10.357.10 89 198 1.0E-23 T 28-03-2018 SMD44_RS28390 d6ed97c887731ebb87c093688cd96768 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 SUPERFAMILY SSF52768 6 340 7.19E-99 T 28-03-2018 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 Pfam PF00850 Histone deacetylase domain 22 316 2.2E-67 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 2.9E-17 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 2.9E-17 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 2.9E-17 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 Gene3D G3DSA:3.40.800.20 3 354 3.6E-90 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 9.6E-11 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 272 288 9.6E-11 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 9.6E-11 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMD44_RS24090 cbe309e294a420fdbd4de2bed2d03b70 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 9.6E-11 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMD44_RS38515 28545f66d14c6858afb2198fb83da4e7 211 Gene3D G3DSA:1.10.260.40 18 190 1.4E-6 T 28-03-2018 SMD44_RS23860 567b35814b2e1c640ae3a33fbfedcb91 153 Pfam PF03965 Penicillinase repressor 1 109 1.3E-23 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMD44_RS23860 567b35814b2e1c640ae3a33fbfedcb91 153 Gene3D G3DSA:1.10.10.10 2 66 1.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23860 567b35814b2e1c640ae3a33fbfedcb91 153 SUPERFAMILY SSF46785 1 110 1.04E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29595 321793e5a364d6aa8a19e96f43a35077 70 ProSitePatterns PS00018 EF-hand calcium-binding domain. 15 27 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMD44_RS29595 321793e5a364d6aa8a19e96f43a35077 70 ProSitePatterns PS00018 EF-hand calcium-binding domain. 52 64 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMD44_RS29595 321793e5a364d6aa8a19e96f43a35077 70 SMART SM00054 6 34 3.5E-5 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SMD44_RS29595 321793e5a364d6aa8a19e96f43a35077 70 SMART SM00054 43 68 80.0 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SMD44_RS29595 321793e5a364d6aa8a19e96f43a35077 70 SUPERFAMILY SSF47473 4 66 4.75E-18 T 28-03-2018 IPR011992 EF-hand domain pair SMD44_RS29595 321793e5a364d6aa8a19e96f43a35077 70 Gene3D G3DSA:1.10.238.10 2 27 5.5E-8 T 28-03-2018 SMD44_RS29595 321793e5a364d6aa8a19e96f43a35077 70 Pfam PF13499 EF-hand domain pair 6 64 9.4E-9 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SMD44_RS29595 321793e5a364d6aa8a19e96f43a35077 70 Gene3D G3DSA:1.10.238.10 28 70 8.8E-13 T 28-03-2018 SMD44_RS13975 0c4bcfc290db74369959b53b0c056eaf 427 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 427 42.38 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD44_RS13975 0c4bcfc290db74369959b53b0c056eaf 427 Pfam PF00171 Aldehyde dehydrogenase family 13 301 4.0E-22 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS13975 0c4bcfc290db74369959b53b0c056eaf 427 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 334 355 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD44_RS13975 0c4bcfc290db74369959b53b0c056eaf 427 SUPERFAMILY SSF53720 10 427 2.36E-119 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS13975 0c4bcfc290db74369959b53b0c056eaf 427 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 21 417 9.6E-157 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD44_RS13975 0c4bcfc290db74369959b53b0c056eaf 427 Gene3D G3DSA:3.40.605.10 3 243 6.2E-49 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS13975 0c4bcfc290db74369959b53b0c056eaf 427 PIRSF PIRSF000151 6 427 1.2E-175 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMD44_RS13975 0c4bcfc290db74369959b53b0c056eaf 427 Gene3D G3DSA:3.40.605.10 244 427 2.2E-39 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS41795 ef044619c3f253c5041a17f559579dc2 412 Gene3D G3DSA:3.40.50.1100 40 146 9.4E-25 T 28-03-2018 SMD44_RS41795 ef044619c3f253c5041a17f559579dc2 412 Gene3D G3DSA:3.40.50.1100 147 332 3.8E-45 T 28-03-2018 SMD44_RS41795 ef044619c3f253c5041a17f559579dc2 412 TIGRFAM TIGR00260 thrC: threonine synthase 12 327 3.9E-83 T 28-03-2018 IPR004450 Threonine synthase-like SMD44_RS41795 ef044619c3f253c5041a17f559579dc2 412 SUPERFAMILY SSF53686 14 335 7.07E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS41795 ef044619c3f253c5041a17f559579dc2 412 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 320 3.2E-71 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS41795 ef044619c3f253c5041a17f559579dc2 412 PIRSF PIRSF038945 1 340 4.3E-144 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 SMD44_RS41795 ef044619c3f253c5041a17f559579dc2 412 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SMD44_RS18230 a43c4d99984907f24c5339c23d5845ea 272 Hamap MF_01240 UPF0309 protein . 27 271 38.796 T 28-03-2018 IPR022951 Uncharacterised protein family UPF0309 SMD44_RS18230 a43c4d99984907f24c5339c23d5845ea 272 Pfam PF13580 SIS domain 30 167 1.2E-39 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS18230 a43c4d99984907f24c5339c23d5845ea 272 Gene3D G3DSA:3.40.50.10490 23 267 2.0E-48 T 28-03-2018 SMD44_RS18230 a43c4d99984907f24c5339c23d5845ea 272 SUPERFAMILY SSF53697 29 230 2.22E-21 T 28-03-2018 SMD44_RS06160 67b98082b6c997efb3359fb309f90c94 191 Gene3D G3DSA:2.60.60.30 19 186 8.8E-67 T 28-03-2018 SMD44_RS06160 67b98082b6c997efb3359fb309f90c94 191 Pfam PF02342 TerD domain 3 187 3.5E-85 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 304 320 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 336 356 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 172 182 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 359 378 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 440 456 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 PRINTS PR00301 70kDa heat shock protein signature 114 134 1.7E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 Gene3D G3DSA:1.20.1270.10 503 588 2.7E-23 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 Pfam PF00012 Hsp70 protein 80 574 1.8E-221 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 Pfam PF00012 Hsp70 protein 4 78 5.6E-29 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 Gene3D G3DSA:2.60.34.10 361 502 3.1E-69 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 SUPERFAMILY SSF100934 478 575 5.49E-14 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 SUPERFAMILY SSF53067 3 159 5.55E-58 T 28-03-2018 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 612 36.197 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 Gene3D G3DSA:3.30.420.40 1 170 7.5E-68 T 28-03-2018 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 Gene3D G3DSA:3.30.420.40 171 332 3.1E-49 T 28-03-2018 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 574 5.0E-279 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 SUPERFAMILY SSF53067 161 353 4.38E-66 T 28-03-2018 SMD44_RS22470 50294120d262a2b9307d16e615e505cd 623 SUPERFAMILY SSF100920 355 511 1.1E-59 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMD44_RS43845 d39c3888b1ceac1221ac5ba61dba22bb 255 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS43845 d39c3888b1ceac1221ac5ba61dba22bb 255 SMART SM00382 28 209 5.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS43845 d39c3888b1ceac1221ac5ba61dba22bb 255 SUPERFAMILY SSF52540 3 223 3.94E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43845 d39c3888b1ceac1221ac5ba61dba22bb 255 Gene3D G3DSA:3.40.50.300 2 251 2.3E-56 T 28-03-2018 SMD44_RS43845 d39c3888b1ceac1221ac5ba61dba22bb 255 Pfam PF00005 ABC transporter 28 161 5.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS15445 9e6ef892e613aef7496e665b33fcb5cd 257 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 24 241 1.8E-36 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SMD44_RS15445 9e6ef892e613aef7496e665b33fcb5cd 257 Pfam PF02096 60Kd inner membrane protein 25 241 1.4E-33 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SMD44_RS42885 875766af55f8ea222eef3fef2a571f15 252 Pfam PF13563 2'-5' RNA ligase superfamily 68 216 2.4E-10 T 28-03-2018 SMD44_RS42885 875766af55f8ea222eef3fef2a571f15 252 Gene3D G3DSA:3.90.1140.10 51 245 8.1E-16 T 28-03-2018 SMD44_RS42885 875766af55f8ea222eef3fef2a571f15 252 SUPERFAMILY SSF55144 66 238 1.92E-15 T 28-03-2018 IPR009097 Cyclic phosphodiesterase SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 Gene3D G3DSA:3.20.20.80 30 322 1.1E-72 T 28-03-2018 SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 ProSitePatterns PS01095 Chitinases family 18 active site. 186 194 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 SUPERFAMILY SSF51445 375 413 8.85E-84 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 SUPERFAMILY SSF51445 48 315 8.85E-84 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 Pfam PF00704 Glycosyl hydrolases family 18 53 405 4.5E-76 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 SMART SM00636 52 405 9.3E-114 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 SUPERFAMILY SSF54556 317 376 9.52E-12 T 28-03-2018 IPR029070 Chitinase insertion domain SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 Gene3D G3DSA:3.20.20.80 365 416 2.3E-8 T 28-03-2018 SMD44_RS06940 3b2252b525e02d8295e8f4cf61d12a68 416 Gene3D G3DSA:3.10.50.10 323 364 6.9E-9 T 28-03-2018 IPR029070 Chitinase insertion domain SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 8.4E-9 T 28-03-2018 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 220 8.4E-9 T 28-03-2018 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 8.4E-9 T 28-03-2018 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 318 8.4E-9 T 28-03-2018 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 325 1.0E-12 T 28-03-2018 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 SUPERFAMILY SSF51905 11 51 8.2E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 SUPERFAMILY SSF51905 79 397 8.2E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 317 4.3E-7 T 28-03-2018 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 202 227 4.3E-7 T 28-03-2018 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 4.3E-7 T 28-03-2018 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 Gene3D G3DSA:3.50.50.60 218 408 1.4E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19720 a7e2eac1551c6ffed494ded563eab2ae 452 Gene3D G3DSA:3.50.50.60 4 217 2.8E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19730 1937fd655ee8fa402bd6009a040ee42d 773 Gene3D G3DSA:3.40.50.300 9 292 2.1E-54 T 28-03-2018 SMD44_RS19730 1937fd655ee8fa402bd6009a040ee42d 773 Pfam PF00271 Helicase conserved C-terminal domain 305 402 2.7E-22 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS19730 1937fd655ee8fa402bd6009a040ee42d 773 SUPERFAMILY SSF52540 139 423 1.1E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19730 1937fd655ee8fa402bd6009a040ee42d 773 Pfam PF00270 DEAD/DEAH box helicase 92 259 2.0E-44 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS19730 1937fd655ee8fa402bd6009a040ee42d 773 SMART SM00490 321 402 2.7E-28 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS19730 1937fd655ee8fa402bd6009a040ee42d 773 Gene3D G3DSA:3.40.50.300 293 514 1.4E-34 T 28-03-2018 SMD44_RS19730 1937fd655ee8fa402bd6009a040ee42d 773 SMART SM00487 87 287 1.5E-50 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 Gene3D G3DSA:3.30.70.370 346 427 9.2E-11 T 28-03-2018 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 Gene3D G3DSA:3.30.420.10 5 237 5.7E-24 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 Gene3D G3DSA:3.30.70.370 431 590 1.6E-17 T 28-03-2018 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 Pfam PF01612 3'-5' exonuclease 16 210 6.8E-15 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 SUPERFAMILY SSF56672 220 582 1.56E-75 T 28-03-2018 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 Pfam PF00476 DNA polymerase family A 247 588 8.0E-55 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 SMART SM00482 372 555 9.1E-36 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 Gene3D G3DSA:1.20.1060.10 238 345 3.8E-12 T 28-03-2018 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 SMART SM00474 15 212 5.9E-11 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMD44_RS35905 8511d79e91e6e63384563ae881467788 598 SUPERFAMILY SSF53098 15 216 8.93E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS27735 f98b4c3ad376964775fe2c8876bd8d65 346 Gene3D G3DSA:3.40.50.300 8 345 7.0E-85 T 28-03-2018 SMD44_RS27735 f98b4c3ad376964775fe2c8876bd8d65 346 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 310 5.5E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS27735 f98b4c3ad376964775fe2c8876bd8d65 346 Pfam PF00005 ABC transporter 40 191 1.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS27735 f98b4c3ad376964775fe2c8876bd8d65 346 SMART SM00382 48 241 5.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS27735 f98b4c3ad376964775fe2c8876bd8d65 346 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS27735 f98b4c3ad376964775fe2c8876bd8d65 346 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 318 1.8E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS27735 f98b4c3ad376964775fe2c8876bd8d65 346 SUPERFAMILY SSF52540 11 263 1.82E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS12450 60efec02e9b23fee80a92acf3a3d7608 139 Gene3D G3DSA:1.10.530.10 6 139 1.2E-16 T 28-03-2018 SMD44_RS12450 60efec02e9b23fee80a92acf3a3d7608 139 SUPERFAMILY SSF53955 66 132 2.39E-11 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS12450 60efec02e9b23fee80a92acf3a3d7608 139 Pfam PF01464 Transglycosylase SLT domain 65 133 4.1E-7 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SMD44_RS23820 3cc96e01636146ed4ac84b5c913a6e44 364 Gene3D G3DSA:3.40.50.720 22 188 1.5E-22 T 28-03-2018 SMD44_RS23820 3cc96e01636146ed4ac84b5c913a6e44 364 SUPERFAMILY SSF51735 26 188 4.01E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS23820 3cc96e01636146ed4ac84b5c913a6e44 364 SUPERFAMILY SSF48179 190 289 1.16E-24 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS23820 3cc96e01636146ed4ac84b5c913a6e44 364 Gene3D G3DSA:1.10.1040.20 189 286 2.3E-37 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 SMD44_RS23820 3cc96e01636146ed4ac84b5c913a6e44 364 Pfam PF10727 Rossmann-like domain 16 140 1.5E-41 T 28-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain SMD44_RS23820 3cc96e01636146ed4ac84b5c913a6e44 364 Pfam PF10728 Domain of unknown function (DUF2520) 157 283 1.0E-38 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 SMD44_RS19805 643d97ec333767e4c282dde3b463a9f6 355 Gene3D G3DSA:3.20.20.100 1 334 3.0E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS19805 643d97ec333767e4c282dde3b463a9f6 355 Pfam PF00248 Aldo/keto reductase family 19 328 3.5E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS19805 643d97ec333767e4c282dde3b463a9f6 355 SUPERFAMILY SSF51430 1 329 8.38E-99 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS19805 643d97ec333767e4c282dde3b463a9f6 355 PRINTS PR00069 Aldo-keto reductase signature 151 168 9.3E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS19805 643d97ec333767e4c282dde3b463a9f6 355 PRINTS PR00069 Aldo-keto reductase signature 120 138 9.3E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS23385 bdb50b47ac1a4e4cbe3cd7ca6c396202 406 Gene3D G3DSA:3.40.50.2000 1 249 3.7E-44 T 28-03-2018 SMD44_RS23385 bdb50b47ac1a4e4cbe3cd7ca6c396202 406 Gene3D G3DSA:3.40.50.2000 250 392 1.1E-29 T 28-03-2018 SMD44_RS23385 bdb50b47ac1a4e4cbe3cd7ca6c396202 406 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 123 3.6E-11 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS23385 bdb50b47ac1a4e4cbe3cd7ca6c396202 406 SUPERFAMILY SSF53756 1 402 1.05E-87 T 28-03-2018 SMD44_RS12375 129fa655430a4558537cacf8a9d7adce 77 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 9 62 4.9E-11 T 28-03-2018 SMD44_RS12375 129fa655430a4558537cacf8a9d7adce 77 SUPERFAMILY SSF54862 5 63 3.35E-11 T 28-03-2018 SMD44_RS12375 129fa655430a4558537cacf8a9d7adce 77 PRINTS PR00352 3Fe-4S ferredoxin signature 20 30 2.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS12375 129fa655430a4558537cacf8a9d7adce 77 PRINTS PR00352 3Fe-4S ferredoxin signature 9 20 2.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS12375 129fa655430a4558537cacf8a9d7adce 77 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 2.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS12375 129fa655430a4558537cacf8a9d7adce 77 Gene3D G3DSA:3.30.70.20 4 64 6.3E-8 T 28-03-2018 SMD44_RS10160 8ea76aaffebb253ca2af9c79b4a7cdb8 215 Pfam PF12385 Papain-like cysteine protease AvrRpt2 59 200 9.7E-18 T 28-03-2018 IPR022118 Peptidase C70, AvrRpt2 SMD44_RS10160 8ea76aaffebb253ca2af9c79b4a7cdb8 215 Gene3D G3DSA:3.90.70.10 48 213 8.9E-30 T 28-03-2018 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 Gene3D G3DSA:3.30.450.20 208 325 2.8E-9 T 28-03-2018 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 SUPERFAMILY SSF55890 327 374 5.49E-9 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 541 9.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 9.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 522 9.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 SUPERFAMILY SSF55874 396 542 1.01E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 542 9.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 Pfam PF00989 PAS fold 225 263 2.2E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 SUPERFAMILY SSF55785 227 269 3.81E-5 T 28-03-2018 IPR000014 PAS domain SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 SUPERFAMILY SSF103190 47 178 4.71E-30 T 28-03-2018 IPR029151 Periplasmic sensor domain-like SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 Gene3D G3DSA:3.30.450.20 42 175 9.2E-23 T 28-03-2018 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 327 372 1.7E-8 T 28-03-2018 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 Pfam PF17203 Single cache domain 3 47 179 3.2E-25 T 28-03-2018 IPR033463 Single cache domain 3 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 SMART SM00387 422 544 5.3E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 Gene3D G3DSA:1.10.287.130 326 379 3.5E-17 T 28-03-2018 SMD44_RS31580 93f571958fd4db86158cc2f5267812c2 556 Gene3D G3DSA:3.30.565.10 380 542 2.4E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS00325 0fa577a7fd4d3f8346c35c1b8b2a2c34 444 Gene3D G3DSA:1.20.1250.20 16 207 5.3E-16 T 28-03-2018 SMD44_RS00325 0fa577a7fd4d3f8346c35c1b8b2a2c34 444 PRINTS PR01988 Putative bacilysin exporter bacE signature 83 101 9.1E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 SMD44_RS00325 0fa577a7fd4d3f8346c35c1b8b2a2c34 444 PRINTS PR01988 Putative bacilysin exporter bacE signature 176 193 9.1E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 SMD44_RS00325 0fa577a7fd4d3f8346c35c1b8b2a2c34 444 PRINTS PR01988 Putative bacilysin exporter bacE signature 20 42 9.1E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 SMD44_RS00325 0fa577a7fd4d3f8346c35c1b8b2a2c34 444 Gene3D G3DSA:1.20.1250.20 220 422 4.9E-16 T 28-03-2018 SMD44_RS00325 0fa577a7fd4d3f8346c35c1b8b2a2c34 444 SUPERFAMILY SSF103473 16 413 4.97E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS00325 0fa577a7fd4d3f8346c35c1b8b2a2c34 444 Pfam PF07690 Major Facilitator Superfamily 24 314 3.5E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS10210 af03e02a57c4dd4c2b29db760b31858a 153 Pfam PF01220 Dehydroquinase class II 10 146 1.8E-59 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS10210 af03e02a57c4dd4c2b29db760b31858a 153 ProSitePatterns PS01029 Dehydroquinase class II signature. 13 30 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS10210 af03e02a57c4dd4c2b29db760b31858a 153 PIRSF PIRSF001399 6 152 1.7E-60 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS10210 af03e02a57c4dd4c2b29db760b31858a 153 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 153 68.316 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS10210 af03e02a57c4dd4c2b29db760b31858a 153 Gene3D G3DSA:3.40.50.9100 6 152 1.2E-63 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS10210 af03e02a57c4dd4c2b29db760b31858a 153 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 23 148 6.0E-56 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS10210 af03e02a57c4dd4c2b29db760b31858a 153 SUPERFAMILY SSF52304 7 149 1.96E-60 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS10210 af03e02a57c4dd4c2b29db760b31858a 153 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 10 147 1.6E-55 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD44_RS10585 4ce8edfc6423f980d1de5054682f61b6 484 SUPERFAMILY SSF51905 20 278 2.85E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10585 4ce8edfc6423f980d1de5054682f61b6 484 Gene3D G3DSA:3.40.50.720 201 423 6.8E-13 T 28-03-2018 SMD44_RS10585 4ce8edfc6423f980d1de5054682f61b6 484 SUPERFAMILY SSF51905 217 385 6.55E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10585 4ce8edfc6423f980d1de5054682f61b6 484 SUPERFAMILY SSF51905 467 480 6.55E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10585 4ce8edfc6423f980d1de5054682f61b6 484 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 22 365 7.7E-112 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD44_RS10585 4ce8edfc6423f980d1de5054682f61b6 484 Gene3D G3DSA:3.50.50.60 12 200 7.4E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS23785 1d98d0e0243f7e58a1f4bb65c4e134dd 395 Gene3D G3DSA:1.10.645.10 28 214 1.1E-50 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS23785 1d98d0e0243f7e58a1f4bb65c4e134dd 395 Gene3D G3DSA:1.10.645.10 226 388 2.0E-25 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS23785 1d98d0e0243f7e58a1f4bb65c4e134dd 395 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 26 395 40.584 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS23785 1d98d0e0243f7e58a1f4bb65c4e134dd 395 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 68 79 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS23785 1d98d0e0243f7e58a1f4bb65c4e134dd 395 SUPERFAMILY SSF56762 41 394 7.46E-101 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS23785 1d98d0e0243f7e58a1f4bb65c4e134dd 395 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 146 395 2.0E-67 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS43795 0d7cc8f7158d39c2d4bd5ad8af369758 265 Gene3D G3DSA:1.10.260.40 7 77 0.0057 T 28-03-2018 SMD44_RS43795 0d7cc8f7158d39c2d4bd5ad8af369758 265 Gene3D G3DSA:1.10.10.10 78 138 0.0035 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09110 70653ce952e7627127754d9a117e0c6d 377 SUPERFAMILY SSF52540 122 374 5.89E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09110 70653ce952e7627127754d9a117e0c6d 377 Pfam PF13614 AAA domain 123 298 8.6E-62 T 28-03-2018 IPR025669 AAA domain SMD44_RS09110 70653ce952e7627127754d9a117e0c6d 377 Gene3D G3DSA:3.40.50.300 121 376 3.4E-60 T 28-03-2018 SMD44_RS15370 16ca8204133eddcfd5c9db1c78c1417c 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 1.3E-26 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD44_RS15370 16ca8204133eddcfd5c9db1c78c1417c 259 SUPERFAMILY SSF56784 7 257 6.96E-68 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS15370 16ca8204133eddcfd5c9db1c78c1417c 259 PIRSF PIRSF000915 3 259 1.2E-53 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD44_RS15370 16ca8204133eddcfd5c9db1c78c1417c 259 Pfam PF13242 HAD-hyrolase-like 182 255 2.1E-20 T 28-03-2018 SMD44_RS15370 16ca8204133eddcfd5c9db1c78c1417c 259 Gene3D G3DSA:3.40.50.1000 1 259 4.2E-32 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS15370 16ca8204133eddcfd5c9db1c78c1417c 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 8.4E-46 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 Gene3D G3DSA:3.30.365.10 622 793 4.7E-43 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 173 736 1.7E-147 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 SUPERFAMILY SSF54665 16 163 6.02E-43 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 Gene3D G3DSA:3.90.1170.50 20 142 1.7E-35 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 SMART SM01008 36 142 2.1E-47 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 36 142 1.6E-33 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 SUPERFAMILY SSF56003 134 791 1.01E-152 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 Gene3D G3DSA:3.30.365.10 182 288 2.6E-30 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 Gene3D G3DSA:3.30.365.10 485 621 6.8E-22 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS33035 6b8cf8bd28d1ce9b17b6b5d4f5cca363 794 Gene3D G3DSA:3.30.365.10 289 448 2.6E-44 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 560 590 - T 28-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 126 423 3.1E-32 T 28-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 SUPERFAMILY SSF53474 477 720 2.03E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 654 676 5.2E-5 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 526 550 5.2E-5 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 583 603 5.2E-5 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 SUPERFAMILY SSF82171 33 78 3.4E-34 T 28-03-2018 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 SUPERFAMILY SSF82171 143 413 3.4E-34 T 28-03-2018 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 Gene3D G3DSA:3.40.50.1820 451 723 3.3E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 Gene3D G3DSA:2.140.10.30 21 450 1.5E-56 T 28-03-2018 SMD44_RS27740 151654042c0f5c8d0bc505527e8fc16d 723 Pfam PF00326 Prolyl oligopeptidase family 520 721 5.5E-41 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD44_RS31815 7e5ba581488721b3418521b7273e015b 261 PIRSF PIRSF006648 1 259 8.5E-68 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS31815 7e5ba581488721b3418521b7273e015b 261 Pfam PF01061 ABC-2 type transporter 12 223 1.3E-28 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 124 8.2E-6 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 SMART SM00922 143 236 9.7E-21 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 Pfam PF13378 Enolase C-terminal domain-like 147 351 5.1E-48 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 Gene3D G3DSA:3.20.20.120 134 349 9.2E-61 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 SUPERFAMILY SSF51604 124 359 3.28E-66 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 12 332 2.0E-95 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 Gene3D G3DSA:3.30.390.10 4 133 8.2E-32 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 SUPERFAMILY SSF54826 4 125 2.02E-26 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01800 3d330ccafadb3d19abd1afcddb403e17 369 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 3 360 41.096 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS30730 738a6f63e9094ae78b383d0c2e6b1177 270 SUPERFAMILY SSF161098 9 258 3.55E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30730 738a6f63e9094ae78b383d0c2e6b1177 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 256 2.9E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30730 738a6f63e9094ae78b383d0c2e6b1177 270 Gene3D G3DSA:1.10.3720.10 13 270 1.0E-35 T 28-03-2018 SMD44_RS22655 8ddff42f812c971df47416d11bb580d6 306 SUPERFAMILY SSF52540 4 218 5.74E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22655 8ddff42f812c971df47416d11bb580d6 306 SMART SM00382 29 208 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS22655 8ddff42f812c971df47416d11bb580d6 306 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS22655 8ddff42f812c971df47416d11bb580d6 306 Pfam PF13732 Domain of unknown function (DUF4162) 212 289 2.3E-6 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 SMD44_RS22655 8ddff42f812c971df47416d11bb580d6 306 Gene3D G3DSA:3.40.50.300 1 299 4.7E-59 T 28-03-2018 SMD44_RS22655 8ddff42f812c971df47416d11bb580d6 306 Pfam PF00005 ABC transporter 20 159 5.4E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 Pfam PF13646 HEAT repeats 178 263 3.6E-10 T 28-03-2018 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 Gene3D G3DSA:1.10.1660.10 1 56 1.5E-20 T 28-03-2018 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 SMART SM00567 E-Z type HEAT repeats 287 316 120.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 SMART SM00567 E-Z type HEAT repeats 189 218 0.1 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 SMART SM00567 E-Z type HEAT repeats 220 249 66.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 Gene3D G3DSA:1.25.40.70 146 234 5.8E-12 T 28-03-2018 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 Gene3D G3DSA:1.25.40.70 236 330 0.4 T 28-03-2018 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 9.4E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 9.4E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 9.4E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 SUPERFAMILY SSF48371 119 328 5.76E-17 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 Pfam PF13411 MerR HTH family regulatory protein 3 67 3.3E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 Gene3D G3DSA:1.10.1660.10 57 142 1.8E-5 T 28-03-2018 SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 SUPERFAMILY SSF46955 3 102 8.42E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS01400 f6463fbe08b6d9e825381f49cf11d743 334 SMART SM00422 1 70 2.9E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 4.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 SUPERFAMILY SSF46785 13 82 1.37E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 Gene3D G3DSA:3.40.1410.10 85 249 2.5E-30 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 SMART SM00866 101 241 1.8E-18 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 SMART SM00345 21 80 2.3E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 SUPERFAMILY SSF64288 68 247 1.04E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.3E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.3E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 Pfam PF07702 UTRA domain 105 240 9.5E-26 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS08635 1d1f7d68ad662eb2bc5d9b5d2f21e21b 249 Gene3D G3DSA:1.10.10.10 6 82 1.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14005 c1832ec6ca7a12c7e788fb2cb6809823 106 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS14005 c1832ec6ca7a12c7e788fb2cb6809823 106 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 4.5E-31 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14005 c1832ec6ca7a12c7e788fb2cb6809823 106 SUPERFAMILY SSF141091 1 101 6.54E-30 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14005 c1832ec6ca7a12c7e788fb2cb6809823 106 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 9.2E-26 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14005 c1832ec6ca7a12c7e788fb2cb6809823 106 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 21.98 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS01330 8f5e53adb89500145b22a1309cf15392 574 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 246 394 3.6E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS01330 8f5e53adb89500145b22a1309cf15392 574 SUPERFAMILY SSF47203 245 400 1.1E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS01330 8f5e53adb89500145b22a1309cf15392 574 Gene3D G3DSA:2.40.110.10 137 232 4.8E-11 T 28-03-2018 SMD44_RS01330 8f5e53adb89500145b22a1309cf15392 574 Gene3D G3DSA:1.20.140.10 233 402 1.9E-19 T 28-03-2018 SMD44_RS01330 8f5e53adb89500145b22a1309cf15392 574 SUPERFAMILY SSF56645 16 240 8.25E-24 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS01330 8f5e53adb89500145b22a1309cf15392 574 Gene3D G3DSA:1.10.540.10 14 136 3.4E-4 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS36270 7d27386968e3c9197acff752bce0a9e9 261 Gene3D G3DSA:1.10.10.10 1 98 2.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36270 7d27386968e3c9197acff752bce0a9e9 261 Gene3D G3DSA:1.25.40.10 100 261 8.1E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36270 7d27386968e3c9197acff752bce0a9e9 261 SUPERFAMILY SSF46894 2 95 2.21E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS36270 7d27386968e3c9197acff752bce0a9e9 261 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 93 1.7E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS36270 7d27386968e3c9197acff752bce0a9e9 261 Pfam PF03704 Bacterial transcriptional activator domain 102 246 1.8E-40 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS36270 7d27386968e3c9197acff752bce0a9e9 261 SMART SM01043 102 246 7.0E-46 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS36270 7d27386968e3c9197acff752bce0a9e9 261 SUPERFAMILY SSF48452 97 257 1.48E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36270 7d27386968e3c9197acff752bce0a9e9 261 SMART SM00862 14 95 0.0019 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS30700 a8e80e3cec9ae113c3a3dd907d6ce098 352 Pfam PF00962 Adenosine/AMP deaminase 20 338 6.8E-90 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMD44_RS30700 a8e80e3cec9ae113c3a3dd907d6ce098 352 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 20 341 4.9E-82 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMD44_RS30700 a8e80e3cec9ae113c3a3dd907d6ce098 352 Gene3D G3DSA:3.20.20.140 8 352 2.2E-78 T 28-03-2018 SMD44_RS30700 a8e80e3cec9ae113c3a3dd907d6ce098 352 SUPERFAMILY SSF51556 13 345 1.4E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.5E-38 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.5E-38 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.5E-38 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.884 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 2.0E-23 T 28-03-2018 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 Gene3D G3DSA:1.10.1900.20 56 116 1.2E-27 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 113 3.8E-44 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 Pfam PF00453 Ribosomal protein L20 3 109 3.4E-44 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07915 cef75bdb700d2b18a6e5ae415e66f573 127 SUPERFAMILY SSF74731 3 117 3.14E-45 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 SUPERFAMILY SSF55486 268 484 1.1E-46 T 28-03-2018 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 225 240 5.4E-12 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 332 347 5.4E-12 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 351 363 5.4E-12 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 5.4E-12 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 Gene3D G3DSA:2.60.40.1730 58 243 7.2E-48 T 28-03-2018 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 Pfam PF01433 Peptidase family M1 domain 328 477 8.5E-26 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 SUPERFAMILY SSF63737 49 241 3.27E-39 T 28-03-2018 SMD44_RS18890 2d2b5d97997385d8e7f04dbc4feeb0c7 487 Gene3D G3DSA:1.10.390.10 325 481 1.5E-34 T 28-03-2018 SMD44_RS32055 d88f145dc7d1a74c54000cac29ea954b 212 Pfam PF00005 ABC transporter 22 162 9.6E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS32055 d88f145dc7d1a74c54000cac29ea954b 212 Gene3D G3DSA:3.40.50.300 5 212 4.2E-48 T 28-03-2018 SMD44_RS32055 d88f145dc7d1a74c54000cac29ea954b 212 SUPERFAMILY SSF52540 4 209 6.49E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32055 d88f145dc7d1a74c54000cac29ea954b 212 SMART SM00382 30 206 8.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 SUPERFAMILY SSF63829 4 275 2.78E-50 T 28-03-2018 SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 252 2.4E-72 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 Gene3D G3DSA:2.120.10.30 1 282 1.2E-31 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 151 171 3.1E-40 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 191 208 3.1E-40 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 233 251 3.1E-40 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 128 150 3.1E-40 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 89 110 3.1E-40 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS19860 9c220c5edb88ddfc82447caa83815680 282 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 3.1E-40 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS00580 b6ae25f360e353289507d952ad8d2844 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 5.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00580 b6ae25f360e353289507d952ad8d2844 188 SUPERFAMILY SSF46689 5 73 6.16E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00580 b6ae25f360e353289507d952ad8d2844 188 Gene3D G3DSA:1.10.10.60 3 53 4.4E-12 T 28-03-2018 SMD44_RS00580 b6ae25f360e353289507d952ad8d2844 188 Gene3D G3DSA:1.10.357.10 54 184 2.1E-11 T 28-03-2018 SMD44_RS00580 b6ae25f360e353289507d952ad8d2844 188 SUPERFAMILY SSF48498 115 156 1.54E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 SMART SM00823 Phosphopantetheine attachment site 527 596 3.7E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 Gene3D G3DSA:3.40.50.980 4 133 3.1E-34 T 28-03-2018 SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 Gene3D G3DSA:2.30.38.10 315 399 2.2E-17 T 28-03-2018 SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 SUPERFAMILY SSF56801 3 504 2.62E-133 T 28-03-2018 SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 34 430 4.6E-116 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 Gene3D G3DSA:3.40.50.980 141 314 4.9E-38 T 28-03-2018 SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 Pfam PF00501 AMP-binding enzyme 13 407 2.2E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 Pfam PF00550 Phosphopantetheine attachment site 528 590 8.3E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 489 1.5E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 SUPERFAMILY SSF47336 525 593 2.49E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 Gene3D G3DSA:1.10.1200.10 521 598 3.1E-20 T 28-03-2018 SMD44_RS31855 817e38771137444a0255fd514a6c49f9 598 Gene3D G3DSA:3.30.300.30 401 506 6.9E-32 T 28-03-2018 SMD44_RS02850 c35de8dae03033848b884873459204b6 219 Gene3D G3DSA:3.40.50.720 1 177 5.8E-28 T 28-03-2018 SMD44_RS02850 c35de8dae03033848b884873459204b6 219 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 6.0E-20 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMD44_RS02850 c35de8dae03033848b884873459204b6 219 SUPERFAMILY SSF51735 1 197 1.36E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34660 b15bde918510e6f171af5af1bfad271b 326 Gene3D G3DSA:1.10.1040.10 196 325 2.1E-29 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS34660 b15bde918510e6f171af5af1bfad271b 326 Gene3D G3DSA:3.40.50.720 1 195 9.4E-34 T 28-03-2018 SMD44_RS34660 b15bde918510e6f171af5af1bfad271b 326 SUPERFAMILY SSF48179 196 313 2.72E-26 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS34660 b15bde918510e6f171af5af1bfad271b 326 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 104 9.0E-25 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS34660 b15bde918510e6f171af5af1bfad271b 326 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 196 314 9.1E-27 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS34660 b15bde918510e6f171af5af1bfad271b 326 SUPERFAMILY SSF51735 2 108 4.11E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS26965 731399eb432e3459968850d2609208e7 202 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 189 8.2E-46 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SMD44_RS26965 731399eb432e3459968850d2609208e7 202 SUPERFAMILY SSF52972 6 191 8.5E-53 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SMD44_RS26965 731399eb432e3459968850d2609208e7 202 PIRSF PIRSF006305 1 197 4.8E-43 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SMD44_RS26965 731399eb432e3459968850d2609208e7 202 Hamap MF_00528 Septum formation protein Maf [maf]. 7 196 28.454 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SMD44_RS26965 731399eb432e3459968850d2609208e7 202 Pfam PF02545 Maf-like protein 7 191 3.8E-46 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 SMD44_RS26965 731399eb432e3459968850d2609208e7 202 Gene3D G3DSA:3.90.950.10 6 199 9.0E-64 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 SUPERFAMILY SSF50494 219 432 1.99E-56 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 Gene3D G3DSA:2.30.42.10 432 536 5.8E-17 T 28-03-2018 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 Pfam PF13365 Trypsin-like peptidase domain 246 391 9.9E-35 T 28-03-2018 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 Gene3D G3DSA:2.40.10.10 215 321 1.1E-29 T 28-03-2018 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 SUPERFAMILY SSF50156 420 528 1.31E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 Gene3D G3DSA:2.40.10.10 322 431 1.6E-37 T 28-03-2018 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 Pfam PF13180 PDZ domain 439 529 2.7E-25 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 PRINTS PR00834 HtrA/DegQ protease family signature 384 401 9.0E-44 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 PRINTS PR00834 HtrA/DegQ protease family signature 255 267 9.0E-44 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 PRINTS PR00834 HtrA/DegQ protease family signature 279 299 9.0E-44 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 PRINTS PR00834 HtrA/DegQ protease family signature 321 345 9.0E-44 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 PRINTS PR00834 HtrA/DegQ protease family signature 362 379 9.0E-44 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 PRINTS PR00834 HtrA/DegQ protease family signature 478 490 9.0E-44 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS20595 4bf87b89369d279317bb735a2f2bab2c 536 SMART SM00228 450 520 1.1E-4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 SUPERFAMILY SSF55060 173 287 6.62E-23 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 SUPERFAMILY SSF54211 10 164 9.87E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 Pfam PF00288 GHMP kinases N terminal domain 95 153 1.7E-4 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 11 295 29.527 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 Pfam PF08544 GHMP kinases C terminal 209 285 4.0E-11 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 Gene3D G3DSA:3.30.70.890 169 297 1.1E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 11 279 2.2E-49 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 PIRSF PIRSF010376 9 302 1.5E-75 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMD44_RS17060 bcadcf6c432919e8c8fbc9c32e5051da 303 Gene3D G3DSA:3.30.230.10 11 168 3.5E-45 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS37725 9ee4c844779522fcdfe8ab6de49497a4 241 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 193 1.3E-18 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37725 9ee4c844779522fcdfe8ab6de49497a4 241 SUPERFAMILY SSF88659 132 194 1.9E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37725 9ee4c844779522fcdfe8ab6de49497a4 241 Pfam PF04542 Sigma-70 region 2 20 68 5.9E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37725 9ee4c844779522fcdfe8ab6de49497a4 241 Gene3D G3DSA:1.10.10.10 105 198 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37725 9ee4c844779522fcdfe8ab6de49497a4 241 Gene3D G3DSA:1.10.1740.10 1 104 5.7E-20 T 28-03-2018 SMD44_RS37725 9ee4c844779522fcdfe8ab6de49497a4 241 SUPERFAMILY SSF88946 4 111 7.06E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37725 9ee4c844779522fcdfe8ab6de49497a4 241 Pfam PF08281 Sigma-70, region 4 140 191 1.6E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS43045 0b15e54c81df70480758d1cf6a5632e4 414 Gene3D G3DSA:1.10.260.40 136 202 6.0E-10 T 28-03-2018 SMD44_RS43045 0b15e54c81df70480758d1cf6a5632e4 414 SMART SM00530 144 200 0.0019 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS43045 0b15e54c81df70480758d1cf6a5632e4 414 Pfam PF13560 Helix-turn-helix domain 141 199 5.6E-9 T 28-03-2018 SMD44_RS43045 0b15e54c81df70480758d1cf6a5632e4 414 SUPERFAMILY SSF47413 142 206 1.32E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS07335 3250b981f6e6b08d10113175793c11a2 604 Gene3D G3DSA:1.10.565.10 36 462 8.8E-5 T 28-03-2018 SMD44_RS07335 3250b981f6e6b08d10113175793c11a2 604 Pfam PF02618 YceG-like family 293 595 6.7E-65 T 28-03-2018 IPR003770 Endolytic murein transglycosylase SMD44_RS07335 3250b981f6e6b08d10113175793c11a2 604 Gene3D G3DSA:3.30.160.60 570 604 4.6E-7 T 28-03-2018 SMD44_RS07335 3250b981f6e6b08d10113175793c11a2 604 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 251 599 27.939 T 28-03-2018 IPR003770 Endolytic murein transglycosylase SMD44_RS07335 3250b981f6e6b08d10113175793c11a2 604 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 287 602 9.1E-53 T 28-03-2018 IPR003770 Endolytic murein transglycosylase SMD44_RS32860 ce4604ff3c4ed5e0f07cb8f74a314fa4 544 SUPERFAMILY SSF56645 59 280 6.62E-31 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS32860 ce4604ff3c4ed5e0f07cb8f74a314fa4 544 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 438 6.4E-33 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS32860 ce4604ff3c4ed5e0f07cb8f74a314fa4 544 Gene3D G3DSA:1.20.140.10 275 448 9.6E-38 T 28-03-2018 SMD44_RS32860 ce4604ff3c4ed5e0f07cb8f74a314fa4 544 Gene3D G3DSA:2.40.110.10 173 274 1.3E-19 T 28-03-2018 SMD44_RS32860 ce4604ff3c4ed5e0f07cb8f74a314fa4 544 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 397 416 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS32860 ce4604ff3c4ed5e0f07cb8f74a314fa4 544 SUPERFAMILY SSF47203 290 442 1.77E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS32860 ce4604ff3c4ed5e0f07cb8f74a314fa4 544 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 275 2.3E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS39800 78e5456063e09df973bca2415444effb 511 SUPERFAMILY SSF56801 39 118 2.15E-16 T 28-03-2018 SMD44_RS39800 78e5456063e09df973bca2415444effb 511 SUPERFAMILY SSF52777 280 380 4.22E-20 T 28-03-2018 SMD44_RS39800 78e5456063e09df973bca2415444effb 511 Gene3D G3DSA:3.30.300.30 3 110 4.7E-22 T 28-03-2018 SMD44_RS39800 78e5456063e09df973bca2415444effb 511 Gene3D G3DSA:1.10.1200.10 111 160 3.2E-15 T 28-03-2018 SMD44_RS39800 78e5456063e09df973bca2415444effb 511 Pfam PF00668 Condensation domain 295 494 9.8E-37 T 28-03-2018 IPR001242 Condensation domain SMD44_RS39800 78e5456063e09df973bca2415444effb 511 ProSitePatterns PS00012 Phosphopantetheine attachment site. 129 144 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS39800 78e5456063e09df973bca2415444effb 511 Pfam PF00550 Phosphopantetheine attachment site 107 146 2.4E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS39800 78e5456063e09df973bca2415444effb 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 32 81 2.2E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS39800 78e5456063e09df973bca2415444effb 511 SUPERFAMILY SSF52777 392 494 1.67E-25 T 28-03-2018 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 SMART SM00382 437 620 3.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 64 266 2.9E-63 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 263 9.7E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 SUPERFAMILY SSF161098 17 265 3.79E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 Gene3D G3DSA:1.10.3720.10 19 269 1.3E-37 T 28-03-2018 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 Pfam PF00005 ABC transporter 432 570 2.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 Gene3D G3DSA:2.40.50.100 678 756 1.5E-19 T 28-03-2018 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 41 263 1.2E-67 T 28-03-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 SUPERFAMILY SSF50331 645 759 2.98E-20 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 Pfam PF03459 TOBE domain 697 758 1.4E-13 T 28-03-2018 IPR005116 Transport-associated OB, type 1 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 Gene3D G3DSA:3.40.50.300 406 663 3.7E-59 T 28-03-2018 SMD44_RS13015 55356a1052e1ae089f531f877b060876 762 SUPERFAMILY SSF52540 433 646 3.68E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21705 ad08e39ef4236fa4ab91e2d9da9b2a1d 270 SUPERFAMILY SSF75217 118 262 2.09E-28 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SMD44_RS21705 ad08e39ef4236fa4ab91e2d9da9b2a1d 270 Pfam PF00588 SpoU rRNA Methylase family 128 257 5.2E-24 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMD44_RS21705 ad08e39ef4236fa4ab91e2d9da9b2a1d 270 Gene3D G3DSA:3.40.1280.10 105 269 1.0E-29 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 Pfam PF01078 Magnesium chelatase, subunit ChlI 113 182 3.0E-7 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 SMART SM00382 28 205 5.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 Gene3D G3DSA:3.40.50.300 2 202 1.6E-21 T 28-03-2018 SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 Pfam PF13519 von Willebrand factor type A domain 484 590 4.5E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 Gene3D G3DSA:1.10.8.80 247 335 3.3E-24 T 28-03-2018 SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 Gene3D G3DSA:3.40.50.410 453 623 2.0E-27 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 SUPERFAMILY SSF52540 4 331 1.32E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 SMART SM00327 481 658 4.5E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 5 646 5.0E-257 T 28-03-2018 IPR012804 Cobaltochelatase subunit, putative SMD44_RS09620 9b9bfbd4aa1b540e1099fbed8b2e18bc 671 SUPERFAMILY SSF53300 484 648 2.67E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS11245 ec938cae19824e61dd0b462bee042c5c 259 Gene3D G3DSA:3.40.50.1820 3 246 2.7E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS11245 ec938cae19824e61dd0b462bee042c5c 259 PIRSF PIRSF017388 1 248 1.2E-76 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 SMD44_RS11245 ec938cae19824e61dd0b462bee042c5c 259 SUPERFAMILY SSF53474 15 121 2.14E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS11245 ec938cae19824e61dd0b462bee042c5c 259 SUPERFAMILY SSF53474 174 245 2.14E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS11245 ec938cae19824e61dd0b462bee042c5c 259 Pfam PF12146 Serine aminopeptidase, S33 19 229 1.1E-22 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SMD44_RS12805 6baddd1fc84ff5f612c41022a8c0900e 325 Gene3D G3DSA:1.10.10.10 9 114 2.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12805 6baddd1fc84ff5f612c41022a8c0900e 325 SUPERFAMILY SSF46785 32 114 2.72E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12805 6baddd1fc84ff5f612c41022a8c0900e 325 SUPERFAMILY SSF53850 118 323 1.28E-35 T 28-03-2018 SMD44_RS12805 6baddd1fc84ff5f612c41022a8c0900e 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 32 90 1.5E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS12805 6baddd1fc84ff5f612c41022a8c0900e 325 Gene3D G3DSA:3.40.190.10 207 310 1.2E-22 T 28-03-2018 SMD44_RS12805 6baddd1fc84ff5f612c41022a8c0900e 325 Gene3D G3DSA:3.40.190.10 117 206 6.6E-22 T 28-03-2018 SMD44_RS12805 6baddd1fc84ff5f612c41022a8c0900e 325 Pfam PF03466 LysR substrate binding domain 117 321 3.1E-39 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS03480 cb670a91c52364c59e9228c99dca8342 443 SUPERFAMILY SSF54826 5 134 1.58E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS03480 cb670a91c52364c59e9228c99dca8342 443 SUPERFAMILY SSF51604 136 412 2.95E-77 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS03480 cb670a91c52364c59e9228c99dca8342 443 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 134 1.9E-4 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMD44_RS03480 cb670a91c52364c59e9228c99dca8342 443 SMART SM00922 182 282 1.9E-16 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMD44_RS03480 cb670a91c52364c59e9228c99dca8342 443 Pfam PF13378 Enolase C-terminal domain-like 185 402 3.9E-35 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS03480 cb670a91c52364c59e9228c99dca8342 443 Gene3D G3DSA:3.20.20.120 138 411 2.5E-50 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS03480 cb670a91c52364c59e9228c99dca8342 443 Gene3D G3DSA:3.30.390.10 1 137 1.8E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS41790 4d9418bb91a693a71893eb8efddcd200 279 Pfam PF01553 Acyltransferase 27 147 4.1E-20 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS41790 4d9418bb91a693a71893eb8efddcd200 279 SUPERFAMILY SSF69593 29 202 3.4E-26 T 28-03-2018 SMD44_RS41790 4d9418bb91a693a71893eb8efddcd200 279 SMART SM00563 30 151 2.7E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS41790 4d9418bb91a693a71893eb8efddcd200 279 Gene3D G3DSA:3.40.1130.10 8 230 4.3E-34 T 28-03-2018 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 Gene3D G3DSA:3.20.20.10 25 256 6.4E-51 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 26 267 2.5E-43 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 Gene3D G3DSA:2.40.37.10 257 395 1.6E-18 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 SUPERFAMILY SSF51419 22 269 4.65E-57 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 44 62 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 257 276 8.7E-12 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 44 62 8.7E-12 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 166 179 8.7E-12 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 76 8.7E-12 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01182 Ornithine decarboxylase signature 116 138 7.1E-11 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01182 Ornithine decarboxylase signature 327 337 7.1E-11 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01182 Ornithine decarboxylase signature 42 69 7.1E-11 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01182 Ornithine decarboxylase signature 86 110 7.1E-11 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 PRINTS PR01182 Ornithine decarboxylase signature 16 40 7.1E-11 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMD44_RS40720 540578b5020ae68e539e290b3d1e694f 404 SUPERFAMILY SSF50621 246 389 3.14E-20 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS11485 534e6f2b7d820f3beea52d2a53f4c0ab 399 SUPERFAMILY SSF52540 224 397 8.76E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11485 534e6f2b7d820f3beea52d2a53f4c0ab 399 SUPERFAMILY SSF56281 2 184 8.92E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS11485 534e6f2b7d820f3beea52d2a53f4c0ab 399 Gene3D G3DSA:3.60.15.10 1 217 1.2E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS11485 534e6f2b7d820f3beea52d2a53f4c0ab 399 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 224 397 6.7E-51 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS11485 534e6f2b7d820f3beea52d2a53f4c0ab 399 Gene3D G3DSA:3.40.50.300 224 398 9.7E-54 T 28-03-2018 SMD44_RS05930 07120db1a586bd7ea603e475c8874f49 197 Pfam PF09335 SNARE associated Golgi protein 22 149 3.2E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 Gene3D G3DSA:3.40.50.2300 2 128 1.4E-32 T 28-03-2018 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 Pfam PF00072 Response regulator receiver domain 5 118 9.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 7.9E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 Gene3D G3DSA:1.10.10.10 129 219 3.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 SMART SM00421 154 211 9.5E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 SMART SM00448 3 117 2.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 SUPERFAMILY SSF52172 1 126 5.41E-32 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 SUPERFAMILY SSF46894 149 217 3.33E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 9.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 9.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS06025 22e088d29e03198d706fac1ce3d1d94a 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 9.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26420 8e1234b58cbcbd212c6338185c4286f3 192 Pfam PF08281 Sigma-70, region 4 128 181 2.5E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26420 8e1234b58cbcbd212c6338185c4286f3 192 SUPERFAMILY SSF88946 9 103 7.46E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26420 8e1234b58cbcbd212c6338185c4286f3 192 Gene3D G3DSA:1.10.1740.10 7 97 4.2E-19 T 28-03-2018 SMD44_RS26420 8e1234b58cbcbd212c6338185c4286f3 192 Pfam PF04542 Sigma-70 region 2 29 94 1.3E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26420 8e1234b58cbcbd212c6338185c4286f3 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 184 1.4E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26420 8e1234b58cbcbd212c6338185c4286f3 192 Gene3D G3DSA:1.10.10.10 98 188 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26420 8e1234b58cbcbd212c6338185c4286f3 192 SUPERFAMILY SSF88659 112 185 6.17E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24525 80316d3d971c4cf8bf3b97b4746c967c 307 Gene3D G3DSA:1.10.10.10 20 145 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24525 80316d3d971c4cf8bf3b97b4746c967c 307 SUPERFAMILY SSF53697 119 277 3.34E-17 T 28-03-2018 SMD44_RS24525 80316d3d971c4cf8bf3b97b4746c967c 307 Pfam PF01418 Helix-turn-helix domain, rpiR family 26 97 8.7E-8 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMD44_RS24525 80316d3d971c4cf8bf3b97b4746c967c 307 SUPERFAMILY SSF46689 24 97 8.06E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS24525 80316d3d971c4cf8bf3b97b4746c967c 307 Gene3D G3DSA:3.40.50.10490 146 283 1.3E-16 T 28-03-2018 SMD44_RS24525 80316d3d971c4cf8bf3b97b4746c967c 307 Pfam PF01380 SIS domain 150 275 2.6E-8 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS00815 1da09c851dc10fafb92268e81fe9f6d0 134 Pfam PF01042 Endoribonuclease L-PSP 21 132 4.9E-20 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS00815 1da09c851dc10fafb92268e81fe9f6d0 134 Gene3D G3DSA:3.30.1330.40 7 134 2.0E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS00815 1da09c851dc10fafb92268e81fe9f6d0 134 SUPERFAMILY SSF55298 8 134 6.75E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS10565 2222385931126bf702da164681f38780 478 Gene3D G3DSA:3.40.1380.20 320 472 1.4E-48 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 471 1.4E-168 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 SUPERFAMILY SSF51621 166 338 1.43E-97 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS10565 2222385931126bf702da164681f38780 478 SUPERFAMILY SSF51621 1 75 1.43E-97 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS10565 2222385931126bf702da164681f38780 478 Gene3D G3DSA:3.20.20.60 159 319 5.6E-64 T 28-03-2018 SMD44_RS10565 2222385931126bf702da164681f38780 478 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 SUPERFAMILY SSF50800 70 165 1.59E-26 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMD44_RS10565 2222385931126bf702da164681f38780 478 PRINTS PR01050 Pyruvate kinase family signature 185 199 2.9E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 PRINTS PR01050 Pyruvate kinase family signature 311 327 2.9E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 PRINTS PR01050 Pyruvate kinase family signature 59 75 2.9E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 PRINTS PR01050 Pyruvate kinase family signature 292 310 2.9E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 PRINTS PR01050 Pyruvate kinase family signature 242 266 2.9E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 PRINTS PR01050 Pyruvate kinase family signature 215 241 2.9E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 PRINTS PR01050 Pyruvate kinase family signature 267 291 2.9E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 1.2E-126 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 Gene3D G3DSA:3.20.20.60 1 74 6.7E-17 T 28-03-2018 SMD44_RS10565 2222385931126bf702da164681f38780 478 Gene3D G3DSA:2.40.33.10 75 158 9.9E-28 T 28-03-2018 SMD44_RS10565 2222385931126bf702da164681f38780 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 469 3.1E-27 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS10565 2222385931126bf702da164681f38780 478 SUPERFAMILY SSF52935 321 472 6.54E-39 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 Pfam PF01037 Lrp/AsnC ligand binding domain 79 138 3.2E-14 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 Gene3D G3DSA:3.30.70.920 57 144 5.2E-21 T 28-03-2018 SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 SUPERFAMILY SSF54909 67 141 9.38E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 9.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 9.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 9.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 Gene3D G3DSA:1.10.10.10 7 56 1.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 2.9E-17 T 28-03-2018 SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 SUPERFAMILY SSF46785 6 65 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06090 66df0b7b9ac087024c481fe389d0b645 148 SMART SM00344 6 112 8.6E-36 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS00210 658f6695aec075bdea43304e143d53e9 380 Gene3D G3DSA:3.40.47.10 199 357 5.0E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS00210 658f6695aec075bdea43304e143d53e9 380 SUPERFAMILY SSF53901 41 357 1.55E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS00210 658f6695aec075bdea43304e143d53e9 380 Gene3D G3DSA:3.40.47.10 10 198 6.5E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS00210 658f6695aec075bdea43304e143d53e9 380 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 144 220 2.4E-26 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS00210 658f6695aec075bdea43304e143d53e9 380 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 41 356 5.6E-88 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS00210 658f6695aec075bdea43304e143d53e9 380 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 267 356 1.9E-25 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS26695 3244412aa2d3794f716e36657b8d7aa1 462 Pfam PF01839 FG-GAP repeat 49 90 2.1E-6 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS26695 3244412aa2d3794f716e36657b8d7aa1 462 SMART SM00191 120 177 17.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26695 3244412aa2d3794f716e36657b8d7aa1 462 SMART SM00191 182 234 42.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26695 3244412aa2d3794f716e36657b8d7aa1 462 SMART SM00191 45 109 1.2E-6 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26695 3244412aa2d3794f716e36657b8d7aa1 462 SMART SM00191 247 310 27.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26695 3244412aa2d3794f716e36657b8d7aa1 462 SUPERFAMILY SSF69318 16 191 6.8E-13 T 28-03-2018 SMD44_RS26695 3244412aa2d3794f716e36657b8d7aa1 462 Gene3D G3DSA:2.60.40.680 28 132 7.8E-14 T 28-03-2018 SMD44_RS32850 b26d82e21b2a2109974050b3afcc2d98 188 Pfam PF00583 Acetyltransferase (GNAT) family 61 164 1.7E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS32850 b26d82e21b2a2109974050b3afcc2d98 188 SUPERFAMILY SSF55729 42 170 1.11E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS32850 b26d82e21b2a2109974050b3afcc2d98 188 Gene3D G3DSA:3.40.630.30 28 177 6.1E-18 T 28-03-2018 SMD44_RS23310 0874fe15b30a7723a02e2a70ee356a28 800 Gene3D G3DSA:1.20.1250.20 326 785 0.025 T 28-03-2018 SMD44_RS23310 0874fe15b30a7723a02e2a70ee356a28 800 PIRSF PIRSF001265 21 756 4.1E-264 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SMD44_RS23310 0874fe15b30a7723a02e2a70ee356a28 800 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 30 744 7.1E-201 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SMD44_RS23310 0874fe15b30a7723a02e2a70ee356a28 800 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 26 743 24.387 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SMD44_RS23310 0874fe15b30a7723a02e2a70ee356a28 800 Pfam PF03030 Inorganic H+ pyrophosphatase 37 738 5.9E-238 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 229 4.9E-82 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 Gene3D G3DSA:3.30.930.10 223 356 8.1E-41 T 28-03-2018 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 Gene3D G3DSA:3.30.930.10 3 222 8.1E-52 T 28-03-2018 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 SUPERFAMILY SSF52954 352 456 2.42E-34 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 SUPERFAMILY SSF55681 5 368 2.24E-120 T 28-03-2018 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 Pfam PF03129 Anticodon binding domain 365 453 1.4E-23 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 Gene3D G3DSA:3.40.50.800 357 457 3.4E-26 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 156 332 2.5E-9 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 136 148 2.2E-50 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 2.2E-50 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 316 328 2.2E-50 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 157 174 2.2E-50 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 402 421 2.2E-50 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 206 216 2.2E-50 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 189 206 2.2E-50 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS13535 92c6cd7032899982593b60b66861bc99 459 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 457 49.213 T 28-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 SMD44_RS23905 eddf04308b7d6a49e32585498b0daaa7 194 Gene3D G3DSA:1.10.10.60 1 38 1.1E-21 T 28-03-2018 SMD44_RS23905 eddf04308b7d6a49e32585498b0daaa7 194 SUPERFAMILY SSF46689 4 77 1.18E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS23905 eddf04308b7d6a49e32585498b0daaa7 194 Gene3D G3DSA:1.10.260.40 39 186 7.6E-15 T 28-03-2018 SMD44_RS23905 eddf04308b7d6a49e32585498b0daaa7 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS23905 eddf04308b7d6a49e32585498b0daaa7 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 1.1E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS23905 eddf04308b7d6a49e32585498b0daaa7 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.2E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS23905 eddf04308b7d6a49e32585498b0daaa7 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.2E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS20180 d654542b4a9389e1114c1ea4f239336c 570 Gene3D G3DSA:3.40.50.300 46 518 2.6E-24 T 28-03-2018 SMD44_RS20180 d654542b4a9389e1114c1ea4f239336c 570 Pfam PF05872 Bacterial protein of unknown function (DUF853) 81 569 5.1E-178 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal SMD44_RS20180 d654542b4a9389e1114c1ea4f239336c 570 SUPERFAMILY SSF52540 76 457 1.18E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 Gene3D G3DSA:3.40.50.261 126 294 1.9E-48 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 PIRSF PIRSF001553 1 293 7.1E-113 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 SUPERFAMILY SSF51735 1 128 2.58E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 Gene3D G3DSA:3.40.50.720 1 125 4.1E-39 T 28-03-2018 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 39.009 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 292 8.5E-125 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 Pfam PF02629 CoA binding domain 6 103 6.1E-25 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 SUPERFAMILY SSF52210 129 291 1.13E-46 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 SMART SM00881 4 104 5.4E-29 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 6.3E-34 T 28-03-2018 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 6.3E-34 T 28-03-2018 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 6.3E-34 T 28-03-2018 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 6.3E-34 T 28-03-2018 SMD44_RS26015 ff4fac5639ed205112390ccbde997106 294 Pfam PF00549 CoA-ligase 158 275 1.1E-12 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS02730 699bf5c9ef5ad8080893cb4ee7fa4373 433 SUPERFAMILY SSF53067 83 401 3.75E-49 T 28-03-2018 SMD44_RS02730 699bf5c9ef5ad8080893cb4ee7fa4373 433 SUPERFAMILY SSF46785 13 75 3.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02730 699bf5c9ef5ad8080893cb4ee7fa4373 433 Gene3D G3DSA:3.30.420.40 76 216 1.3E-25 T 28-03-2018 SMD44_RS02730 699bf5c9ef5ad8080893cb4ee7fa4373 433 Gene3D G3DSA:3.30.420.40 217 412 1.0E-48 T 28-03-2018 SMD44_RS02730 699bf5c9ef5ad8080893cb4ee7fa4373 433 Gene3D G3DSA:1.10.10.10 17 75 1.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02730 699bf5c9ef5ad8080893cb4ee7fa4373 433 Pfam PF00480 ROK family 86 399 1.4E-42 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS20960 c07038b6238cee68a9031ac03529dea1 490 Pfam PF00772 DnaB-like helicase N terminal domain 55 156 1.0E-36 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SMD44_RS20960 c07038b6238cee68a9031ac03529dea1 490 SMART SM00382 247 446 2.8E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS20960 c07038b6238cee68a9031ac03529dea1 490 Gene3D G3DSA:3.40.50.300 212 490 7.9E-69 T 28-03-2018 SMD44_RS20960 c07038b6238cee68a9031ac03529dea1 490 Pfam PF03796 DnaB-like helicase C terminal domain 230 485 4.1E-107 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 SMD44_RS20960 c07038b6238cee68a9031ac03529dea1 490 Gene3D G3DSA:1.10.860.10 47 196 9.3E-54 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SMD44_RS20960 c07038b6238cee68a9031ac03529dea1 490 SUPERFAMILY SSF48024 53 164 9.02E-39 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SMD44_RS20960 c07038b6238cee68a9031ac03529dea1 490 SUPERFAMILY SSF52540 228 479 9.84E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20960 c07038b6238cee68a9031ac03529dea1 490 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 55 488 6.9E-166 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 SMD44_RS29475 b4928167e0adbfe72fae578c440e8cb7 158 Gene3D G3DSA:3.90.1200.10 59 141 4.6E-15 T 28-03-2018 SMD44_RS29475 b4928167e0adbfe72fae578c440e8cb7 158 SUPERFAMILY SSF56112 12 139 9.69E-23 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS29475 b4928167e0adbfe72fae578c440e8cb7 158 Pfam PF00069 Protein kinase domain 16 138 4.5E-10 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS29475 b4928167e0adbfe72fae578c440e8cb7 158 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 50 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS29475 b4928167e0adbfe72fae578c440e8cb7 158 Gene3D G3DSA:3.30.200.20 8 58 1.5E-7 T 28-03-2018 SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 SUPERFAMILY SSF48498 86 196 2.49E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 7.2E-23 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 SUPERFAMILY SSF46689 7 87 2.1E-22 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 Gene3D G3DSA:1.10.10.60 2 37 5.2E-17 T 28-03-2018 SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 Gene3D G3DSA:1.10.357.10 83 197 1.1E-14 T 28-03-2018 SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS08520 02985bad3dad4e3a857e5c39d9f81de9 197 Gene3D G3DSA:1.10.260.40 38 82 9.7E-16 T 28-03-2018 SMD44_RS38720 c88d71d87c258309c76550331188083e 350 ProSitePatterns PS00622 LuxR-type HTH domain signature. 302 329 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS38720 c88d71d87c258309c76550331188083e 350 SUPERFAMILY SSF55781 24 164 5.15E-5 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS38720 c88d71d87c258309c76550331188083e 350 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 318 330 4.4E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS38720 c88d71d87c258309c76550331188083e 350 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 288 302 4.4E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS38720 c88d71d87c258309c76550331188083e 350 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 302 318 4.4E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS38720 c88d71d87c258309c76550331188083e 350 Pfam PF00196 Bacterial regulatory proteins, luxR family 290 340 2.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS38720 c88d71d87c258309c76550331188083e 350 SUPERFAMILY SSF46894 290 343 7.82E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS38720 c88d71d87c258309c76550331188083e 350 Gene3D G3DSA:1.10.10.10 228 347 3.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38720 c88d71d87c258309c76550331188083e 350 Gene3D G3DSA:3.30.450.40 3 173 7.3E-9 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS38720 c88d71d87c258309c76550331188083e 350 SMART SM00421 285 342 3.3E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS03010 f15a869cf00bf9e252b4e91a43e708a5 163 Pfam PF00255 Glutathione peroxidase 9 110 1.5E-37 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD44_RS03010 f15a869cf00bf9e252b4e91a43e708a5 163 PIRSF PIRSF000303 1 163 2.2E-60 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD44_RS03010 f15a869cf00bf9e252b4e91a43e708a5 163 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 SMD44_RS03010 f15a869cf00bf9e252b4e91a43e708a5 163 Gene3D G3DSA:3.40.30.10 3 163 2.2E-42 T 28-03-2018 SMD44_RS03010 f15a869cf00bf9e252b4e91a43e708a5 163 PRINTS PR01011 Glutathione peroxidase family signature 22 39 9.3E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD44_RS03010 f15a869cf00bf9e252b4e91a43e708a5 163 PRINTS PR01011 Glutathione peroxidase family signature 123 132 9.3E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD44_RS03010 f15a869cf00bf9e252b4e91a43e708a5 163 PRINTS PR01011 Glutathione peroxidase family signature 57 73 9.3E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD44_RS03010 f15a869cf00bf9e252b4e91a43e708a5 163 SUPERFAMILY SSF52833 1 161 4.29E-53 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS25030 a0fcc5991c9384378175e3649a0efdb0 238 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 69 226 28.073 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25030 a0fcc5991c9384378175e3649a0efdb0 238 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 95 217 1.9E-44 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25030 a0fcc5991c9384378175e3649a0efdb0 238 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 97 218 3.2E-40 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25030 a0fcc5991c9384378175e3649a0efdb0 238 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 146 201 2.0E-26 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25030 a0fcc5991c9384378175e3649a0efdb0 238 SUPERFAMILY SSF143243 82 234 1.44E-45 T 28-03-2018 SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 Gene3D G3DSA:3.40.50.2300 53 180 4.6E-28 T 28-03-2018 SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 Pfam PF13377 Periplasmic binding protein-like domain 175 333 8.5E-32 T 28-03-2018 SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 28-03-2018 SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 SUPERFAMILY SSF53822 58 321 7.07E-47 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 Gene3D G3DSA:1.10.10.10 1 15 0.42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 3.0E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 Gene3D G3DSA:1.10.260.40 16 52 4.7E-21 T 28-03-2018 SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 SUPERFAMILY SSF47413 1 53 7.24E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 Gene3D G3DSA:3.40.50.2300 181 306 1.6E-31 T 28-03-2018 SMD44_RS37125 190e9c2fff8e678a649742b8fa93fb62 342 SMART SM00354 1 68 1.1E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 Gene3D G3DSA:3.40.640.10 171 290 2.5E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 Gene3D G3DSA:3.90.1150.10 7 163 2.2E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 Pfam PF00202 Aminotransferase class-III 30 392 8.0E-101 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 18 394 43.272 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 SUPERFAMILY SSF53383 20 395 3.94E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 PIRSF PIRSF000521 172 396 3.3E-30 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 PIRSF PIRSF000521 29 134 1.7E-5 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 PIRSF PIRSF000521 128 161 0.84 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 Gene3D G3DSA:3.90.1150.10 291 400 4.2E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS36135 34f1cb56245ca27d7e90744fbcd01649 402 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 21 393 1.7E-136 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMD44_RS22180 58f641567e33fb62796c918e1a7cf483 317 Gene3D G3DSA:3.40.50.1820 52 311 3.1E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS22180 58f641567e33fb62796c918e1a7cf483 317 Pfam PF01674 Lipase (class 2) 73 252 1.4E-13 T 28-03-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD44_RS22180 58f641567e33fb62796c918e1a7cf483 317 SUPERFAMILY SSF53474 68 251 2.84E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS03950 6ddfde6e75626ef5c11f1c0e11ca8595 278 Gene3D G3DSA:3.40.50.1860 109 248 1.1E-23 T 28-03-2018 SMD44_RS03950 6ddfde6e75626ef5c11f1c0e11ca8595 278 SUPERFAMILY SSF53681 105 219 6.76E-18 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS03950 6ddfde6e75626ef5c11f1c0e11ca8595 278 SUPERFAMILY SSF53681 2 102 1.83E-18 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS03950 6ddfde6e75626ef5c11f1c0e11ca8595 278 Pfam PF01177 Asp/Glu/Hydantoin racemase 44 210 9.7E-13 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS03950 6ddfde6e75626ef5c11f1c0e11ca8595 278 Gene3D G3DSA:3.40.50.1860 10 108 6.7E-15 T 28-03-2018 SMD44_RS03950 6ddfde6e75626ef5c11f1c0e11ca8595 278 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 66 74 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 SUPERFAMILY SSF55021 779 860 2.79E-15 T 28-03-2018 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 SUPERFAMILY SSF109604 138 312 1.51E-71 T 28-03-2018 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 150 856 1.7E-258 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 SUPERFAMILY SSF81271 510 582 3.49E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 Gene3D G3DSA:3.30.70.260 784 862 1.8E-13 T 28-03-2018 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 Pfam PF04607 Region found in RelA / SpoT proteins 357 466 4.9E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 SMART SM00954 357 467 2.5E-64 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 Gene3D G3DSA:3.10.20.30 517 588 8.9E-23 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 Pfam PF13328 HD domain 150 297 3.9E-51 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 Pfam PF02824 TGS domain 523 582 2.6E-20 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 SMART SM00471 165 275 1.1E-12 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 SUPERFAMILY SSF81301 302 527 1.8E-63 T 28-03-2018 SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 Pfam PF13291 ACT domain 780 856 8.1E-17 T 28-03-2018 IPR002912 ACT domain SMD44_RS07420 ccbd9a230d6dae9b122dfbbd05a06ff5 863 Gene3D G3DSA:3.30.460.10 314 447 1.7E-43 T 28-03-2018 SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 Gene3D G3DSA:1.20.1250.20 16 209 4.1E-36 T 28-03-2018 SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 Gene3D G3DSA:1.20.1250.20 264 551 6.3E-25 T 28-03-2018 SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 4.4E-5 T 28-03-2018 SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 4.4E-5 T 28-03-2018 SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 PRINTS PR01036 Tetracycline resistance protein TetB signature 407 426 4.4E-5 T 28-03-2018 SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 4.4E-5 T 28-03-2018 SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 SUPERFAMILY SSF103473 12 209 6.45E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 SUPERFAMILY SSF103473 256 426 6.45E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 SUPERFAMILY SSF103473 509 543 6.45E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 427 4.8E-69 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS29315 1f40fa493f0d3f4dc40e8d496a5f0b36 562 Pfam PF07690 Major Facilitator Superfamily 26 416 3.0E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS06450 d892cff4be9cf59c3663e33130c10bd7 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 9 213 2.4E-78 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD44_RS06450 d892cff4be9cf59c3663e33130c10bd7 227 Gene3D G3DSA:3.40.470.10 2 224 4.1E-95 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD44_RS06450 d892cff4be9cf59c3663e33130c10bd7 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 8 222 40.631 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD44_RS06450 d892cff4be9cf59c3663e33130c10bd7 227 SUPERFAMILY SSF52141 6 222 4.58E-89 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD44_RS06450 d892cff4be9cf59c3663e33130c10bd7 227 Pfam PF03167 Uracil DNA glycosylase superfamily 57 207 1.4E-22 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD44_RS06450 d892cff4be9cf59c3663e33130c10bd7 227 SMART SM00987 52 211 5.2E-33 T 28-03-2018 SMD44_RS06450 d892cff4be9cf59c3663e33130c10bd7 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD44_RS06450 d892cff4be9cf59c3663e33130c10bd7 227 SMART SM00986 52 211 5.2E-33 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD44_RS39210 f4260db57958921f2e8c50cf1f873cec 443 SUPERFAMILY SSF52540 244 371 2.03E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS39210 f4260db57958921f2e8c50cf1f873cec 443 Gene3D G3DSA:2.40.10.10 10 119 3.7E-5 T 28-03-2018 SMD44_RS39210 f4260db57958921f2e8c50cf1f873cec 443 Gene3D G3DSA:3.40.50.300 237 403 1.5E-6 T 28-03-2018 SMD44_RS39210 f4260db57958921f2e8c50cf1f873cec 443 SUPERFAMILY SSF50494 21 214 1.43E-8 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS39210 f4260db57958921f2e8c50cf1f873cec 443 Pfam PF13365 Trypsin-like peptidase domain 34 194 4.5E-8 T 28-03-2018 SMD44_RS07440 a1f1baa362876916fc6bf03854127882 160 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 4 82 1.0E-15 T 28-03-2018 IPR003849 Preprotein translocase YajC SMD44_RS07440 a1f1baa362876916fc6bf03854127882 160 SMART SM01323 1 82 1.9E-19 T 28-03-2018 IPR003849 Preprotein translocase YajC SMD44_RS07440 a1f1baa362876916fc6bf03854127882 160 Pfam PF02699 Preprotein translocase subunit 5 78 4.2E-15 T 28-03-2018 IPR003849 Preprotein translocase YajC SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 Gene3D G3DSA:3.50.50.60 22 163 5.8E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 Gene3D G3DSA:3.50.50.60 164 317 1.3E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 25 47 1.2E-14 T 28-03-2018 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 171 1.2E-14 T 28-03-2018 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 203 228 1.2E-14 T 28-03-2018 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 7.9E-20 T 28-03-2018 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 309 325 7.9E-20 T 28-03-2018 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 26 45 7.9E-20 T 28-03-2018 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 203 221 7.9E-20 T 28-03-2018 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 340 362 7.9E-20 T 28-03-2018 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 Pfam PF04324 BFD-like [2Fe-2S] binding domain 432 478 1.5E-9 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 24 372 2.2E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 SUPERFAMILY SSF51905 141 386 9.72E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 SUPERFAMILY SSF51905 24 111 9.72E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 Gene3D G3DSA:3.50.50.60 318 414 2.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS02805 1a474f520c03c27cf2014f07b6f35145 531 PIRSF PIRSF037495 18 515 1.9E-127 T 28-03-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 SMD44_RS24980 8d084750861e465dbe50b80fd7b89245 444 Pfam PF00145 C-5 cytosine-specific DNA methylase 23 205 3.5E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS24980 8d084750861e465dbe50b80fd7b89245 444 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 25 203 1.0E-30 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD44_RS24980 8d084750861e465dbe50b80fd7b89245 444 SUPERFAMILY SSF53335 372 438 1.3E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS24980 8d084750861e465dbe50b80fd7b89245 444 SUPERFAMILY SSF53335 16 216 1.3E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS24980 8d084750861e465dbe50b80fd7b89245 444 Gene3D G3DSA:3.40.50.150 22 253 9.2E-44 T 28-03-2018 SMD44_RS24980 8d084750861e465dbe50b80fd7b89245 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 124 138 6.8E-11 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD44_RS24980 8d084750861e465dbe50b80fd7b89245 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 189 202 6.8E-11 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD44_RS24980 8d084750861e465dbe50b80fd7b89245 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 22 38 6.8E-11 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD44_RS14510 071f6011c7032d424f699d168374c642 447 SMART SM00327 60 237 3.8E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS14510 071f6011c7032d424f699d168374c642 447 Pfam PF13768 von Willebrand factor type A domain 62 221 3.4E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS14510 071f6011c7032d424f699d168374c642 447 Gene3D G3DSA:3.40.50.410 59 242 4.0E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS14510 071f6011c7032d424f699d168374c642 447 SUPERFAMILY SSF53300 59 238 2.91E-20 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS43390 4ba0e9c417d39b006e67de7b9488b7a2 352 Gene3D G3DSA:3.90.1720.10 224 352 3.0E-32 T 28-03-2018 SMD44_RS43390 4ba0e9c417d39b006e67de7b9488b7a2 352 Gene3D G3DSA:1.10.530.10 44 213 1.0E-31 T 28-03-2018 SMD44_RS43390 4ba0e9c417d39b006e67de7b9488b7a2 352 Pfam PF01464 Transglycosylase SLT domain 75 191 1.4E-12 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SMD44_RS43390 4ba0e9c417d39b006e67de7b9488b7a2 352 Pfam PF00877 NlpC/P60 family 238 348 3.4E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS43390 4ba0e9c417d39b006e67de7b9488b7a2 352 SUPERFAMILY SSF54001 219 351 8.83E-33 T 28-03-2018 SMD44_RS43390 4ba0e9c417d39b006e67de7b9488b7a2 352 SUPERFAMILY SSF53955 56 206 1.53E-27 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS07435 6576fc91843bfa3f842d823fc0a75b3f 610 Pfam PF02355 Protein export membrane protein 391 567 8.7E-13 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMD44_RS07435 6576fc91843bfa3f842d823fc0a75b3f 610 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 44 562 1.4E-104 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMD44_RS07435 6576fc91843bfa3f842d823fc0a75b3f 610 Gene3D G3DSA:1.20.1640.10 350 569 2.8E-28 T 28-03-2018 SMD44_RS07435 6576fc91843bfa3f842d823fc0a75b3f 610 SUPERFAMILY SSF82866 368 569 1.96E-32 T 28-03-2018 SMD44_RS07435 6576fc91843bfa3f842d823fc0a75b3f 610 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 317 554 1.4E-62 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD44_RS07435 6576fc91843bfa3f842d823fc0a75b3f 610 Pfam PF07549 SecD/SecF GG Motif 39 59 2.6E-4 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMD44_RS07435 6576fc91843bfa3f842d823fc0a75b3f 610 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 8 577 38.002 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMD44_RS10830 94c2ccbaa112b9fedf20c954dd604e72 251 Gene3D G3DSA:3.20.20.70 5 247 1.3E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS10830 94c2ccbaa112b9fedf20c954dd604e72 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 251 47.902 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 SMD44_RS10830 94c2ccbaa112b9fedf20c954dd604e72 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 251 6.7E-111 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 SMD44_RS10830 94c2ccbaa112b9fedf20c954dd604e72 251 SUPERFAMILY SSF51366 3 251 6.36E-84 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD44_RS10830 94c2ccbaa112b9fedf20c954dd604e72 251 Pfam PF00977 Histidine biosynthesis protein 6 234 8.9E-88 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 SUPERFAMILY SSF55174 6 204 9.42E-56 T 28-03-2018 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 SMART SM00363 92 158 3.6E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 Gene3D G3DSA:1.10.1050.10 140 204 2.7E-11 T 28-03-2018 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 6 204 6.2E-62 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 Pfam PF01479 S4 domain 92 139 4.7E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 Gene3D G3DSA:1.10.1050.10 1 97 1.4E-29 T 28-03-2018 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 204 29.695 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 SMART SM01390 3 91 7.5E-32 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 91 2.4E-20 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMD44_RS07365 ae06875270da53f292260106dfb2dffe 204 Gene3D G3DSA:3.10.290.10 98 139 4.2E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS37475 1f9429bc6749c03f3f89f0097b37c8aa 254 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 249 41.705 T 28-03-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 SMD44_RS37475 1f9429bc6749c03f3f89f0097b37c8aa 254 Gene3D G3DSA:3.60.20.10 1 212 5.0E-27 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS37475 1f9429bc6749c03f3f89f0097b37c8aa 254 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 249 3.4E-94 T 28-03-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 SMD44_RS37475 1f9429bc6749c03f3f89f0097b37c8aa 254 SUPERFAMILY SSF56235 2 243 1.93E-13 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS37475 1f9429bc6749c03f3f89f0097b37c8aa 254 Pfam PF13522 Glutamine amidotransferase domain 71 220 1.0E-16 T 28-03-2018 SMD44_RS33265 3167d91cf1dcef770e0cc7f7ddc0e847 390 SUPERFAMILY SSF144083 325 387 1.09E-18 T 28-03-2018 SMD44_RS33265 3167d91cf1dcef770e0cc7f7ddc0e847 390 Pfam PF01544 CorA-like Mg2+ transporter protein 84 386 3.6E-65 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD44_RS33265 3167d91cf1dcef770e0cc7f7ddc0e847 390 SUPERFAMILY SSF143865 36 307 1.2E-66 T 28-03-2018 SMD44_RS33265 3167d91cf1dcef770e0cc7f7ddc0e847 390 Gene3D G3DSA:1.20.58.340 310 390 4.4E-16 T 28-03-2018 SMD44_RS33265 3167d91cf1dcef770e0cc7f7ddc0e847 390 Gene3D G3DSA:1.20.58.340 192 309 2.4E-31 T 28-03-2018 SMD44_RS33265 3167d91cf1dcef770e0cc7f7ddc0e847 390 Gene3D G3DSA:3.30.460.20 17 190 2.2E-37 T 28-03-2018 SMD44_RS30240 f75851828d8a8d0b052151fb09ed4b29 238 Pfam PF09339 IclR helix-turn-helix domain 10 57 1.5E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS30240 f75851828d8a8d0b052151fb09ed4b29 238 Gene3D G3DSA:1.10.10.10 1 73 2.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30240 f75851828d8a8d0b052151fb09ed4b29 238 SMART SM00346 7 93 9.5E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS30240 f75851828d8a8d0b052151fb09ed4b29 238 Pfam PF01614 Bacterial transcriptional regulator 125 232 7.1E-16 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS30240 f75851828d8a8d0b052151fb09ed4b29 238 SUPERFAMILY SSF55781 62 234 3.47E-34 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS30240 f75851828d8a8d0b052151fb09ed4b29 238 SUPERFAMILY SSF46785 7 75 8.95E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30240 f75851828d8a8d0b052151fb09ed4b29 238 Gene3D G3DSA:3.30.450.40 74 238 4.9E-34 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Gene3D G3DSA:2.60.40.1120 512 589 1.4E-6 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 410 1.4E-80 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Gene3D G3DSA:1.20.1250.20 1 188 1.5E-35 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Gene3D G3DSA:2.60.40.1120 675 758 2.2E-13 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Gene3D G3DSA:2.60.40.1120 590 674 1.2E-14 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Gene3D G3DSA:1.20.1250.20 240 489 1.9E-33 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 SUPERFAMILY SSF49464 513 590 1.26E-7 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 SUPERFAMILY SSF103473 237 408 2.62E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 SUPERFAMILY SSF103473 451 477 2.62E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 SUPERFAMILY SSF103473 3 190 2.62E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Pfam PF07690 Major Facilitator Superfamily 6 399 5.3E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 SUPERFAMILY SSF49478 680 748 5.49E-11 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Pfam PF13620 Carboxypeptidase regulatory-like domain 680 756 3.0E-12 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Pfam PF13620 Carboxypeptidase regulatory-like domain 515 590 1.4E-8 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 Pfam PF13620 Carboxypeptidase regulatory-like domain 596 674 5.0E-16 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 SUPERFAMILY SSF49452 590 674 1.86E-12 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 149 2.2E-5 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 2.2E-5 T 28-03-2018 SMD44_RS34245 b8aa13cafa70b70fbcf1a51ae3ce300d 760 PRINTS PR01036 Tetracycline resistance protein TetB signature 95 115 2.2E-5 T 28-03-2018 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Gene3D G3DSA:1.10.10.10 8 114 5.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SUPERFAMILY SSF48452 909 1070 1.48E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SUPERFAMILY SSF46894 24 92 1.16E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Pfam PF03704 Bacterial transcriptional activator domain 121 266 2.7E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 PRINTS PR00364 Disease resistance protein signature 489 503 4.6E-10 T 28-03-2018 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 PRINTS PR00364 Disease resistance protein signature 323 338 4.6E-10 T 28-03-2018 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 PRINTS PR00364 Disease resistance protein signature 401 415 4.6E-10 T 28-03-2018 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SMART SM00862 31 102 1.3E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Pfam PF00931 NB-ARC domain 322 551 1.7E-13 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Gene3D G3DSA:1.25.40.10 999 1088 3.1E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Pfam PF13424 Tetratricopeptide repeat 988 1060 1.4E-9 T 28-03-2018 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Gene3D G3DSA:1.10.10.10 540 736 0.051 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Gene3D G3DSA:1.10.150.200 938 998 2.4E-6 T 28-03-2018 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SUPERFAMILY SSF48452 739 898 7.59E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SMART SM01043 121 266 3.8E-52 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SUPERFAMILY SSF48452 116 288 4.49E-39 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 94 2.2E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Gene3D G3DSA:1.25.40.10 118 291 1.9E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SMART SM00028 1028 1061 18.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SMART SM00028 908 941 480.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SMART SM00028 948 981 32.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SMART SM00028 988 1021 0.03 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SMART SM00028 788 821 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SMART SM00028 868 901 320.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 SUPERFAMILY SSF52540 287 558 4.28E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Gene3D G3DSA:1.25.40.10 737 935 1.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36080 2fe0d74b260f576eed4b961e89b003b7 1092 Gene3D G3DSA:3.40.50.300 292 443 9.2E-18 T 28-03-2018 SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 SUPERFAMILY SSF103473 242 414 3.01E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 SUPERFAMILY SSF103473 8 187 3.01E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 SUPERFAMILY SSF103473 461 487 3.01E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 8 485 1.3E-84 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 Pfam PF07690 Major Facilitator Superfamily 12 404 5.9E-57 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 Gene3D G3DSA:1.20.1250.20 8 194 1.2E-38 T 28-03-2018 SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 Gene3D G3DSA:1.10.10.10 483 646 2.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 SUPERFAMILY SSF46785 540 640 4.91E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 2.9E-6 T 28-03-2018 SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 2.9E-6 T 28-03-2018 SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 2.9E-6 T 28-03-2018 SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 2.9E-6 T 28-03-2018 SMD44_RS12505 14082db56b43a98acf88043a22bb6fd8 659 Gene3D G3DSA:1.20.1250.20 246 482 3.0E-34 T 28-03-2018 SMD44_RS20495 78a6330106e001dd93e3ad6c1b661e9d 351 Gene3D G3DSA:1.25.40.10 58 349 3.7E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS20495 78a6330106e001dd93e3ad6c1b661e9d 351 SUPERFAMILY SSF48452 110 307 1.56E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS29570 e663094f7793034acea19b1b76131c5e 256 Gene3D G3DSA:1.10.12.10 217 255 8.6E-13 T 28-03-2018 IPR014748 Crontonase, C-terminal SMD44_RS29570 e663094f7793034acea19b1b76131c5e 256 SUPERFAMILY SSF52096 1 254 9.81E-86 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS29570 e663094f7793034acea19b1b76131c5e 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD44_RS29570 e663094f7793034acea19b1b76131c5e 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 249 3.7E-69 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS29570 e663094f7793034acea19b1b76131c5e 256 Gene3D G3DSA:3.90.226.10 1 216 8.1E-76 T 28-03-2018 SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.6E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 Pfam PF03466 LysR substrate binding domain 89 296 1.9E-43 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 SUPERFAMILY SSF53850 91 297 1.09E-36 T 28-03-2018 SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 Gene3D G3DSA:1.10.10.10 1 84 4.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 Gene3D G3DSA:3.40.190.10 182 270 2.8E-24 T 28-03-2018 SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 Gene3D G3DSA:3.40.190.10 90 181 8.0E-26 T 28-03-2018 SMD44_RS25795 e56401d9670f8f08dacd908ec8e65432 298 SUPERFAMILY SSF46785 2 112 4.93E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02845 ed966bffc86d12f6c40937559eef4df9 368 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS02845 ed966bffc86d12f6c40937559eef4df9 368 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 320 1.7E-13 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS02845 ed966bffc86d12f6c40937559eef4df9 368 SUPERFAMILY SSF52540 15 260 6.74E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS02845 ed966bffc86d12f6c40937559eef4df9 368 SMART SM00382 47 246 7.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS02845 ed966bffc86d12f6c40937559eef4df9 368 Pfam PF00005 ABC transporter 39 188 5.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS02845 ed966bffc86d12f6c40937559eef4df9 368 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 342 5.3E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS02845 ed966bffc86d12f6c40937559eef4df9 368 Gene3D G3DSA:3.40.50.300 12 355 3.8E-85 T 28-03-2018 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 PIRSF PIRSF000521 165 391 1.0E-29 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 PIRSF PIRSF000521 119 150 5.3 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 PIRSF PIRSF000521 23 128 1.2E-5 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 Gene3D G3DSA:3.90.1150.10 286 395 4.9E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 Gene3D G3DSA:3.90.1150.10 1 162 3.1E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 215 253 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 SUPERFAMILY SSF53383 15 389 2.5E-118 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 Pfam PF00202 Aminotransferase class-III 24 384 4.8E-106 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 15 388 9.5E-137 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 389 43.204 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMD44_RS07790 a2611ad15156e5d5821dea8242eb519d 408 Gene3D G3DSA:3.40.640.10 163 285 8.4E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS30115 4ece6abc76e003b788ff569d4915ee3d 301 Gene3D G3DSA:3.40.50.1820 6 296 2.7E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS30115 4ece6abc76e003b788ff569d4915ee3d 301 Pfam PF00561 alpha/beta hydrolase fold 29 274 2.4E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS30115 4ece6abc76e003b788ff569d4915ee3d 301 SUPERFAMILY SSF53474 6 290 6.89E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS03710 b40b561449eaccc1994fc739a334c857 361 SUPERFAMILY SSF52540 29 279 2.34E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS03710 b40b561449eaccc1994fc739a334c857 361 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 259 327 4.2E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS03710 b40b561449eaccc1994fc739a334c857 361 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS03710 b40b561449eaccc1994fc739a334c857 361 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 257 346 5.6E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS03710 b40b561449eaccc1994fc739a334c857 361 SMART SM00382 65 257 2.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS03710 b40b561449eaccc1994fc739a334c857 361 Gene3D G3DSA:3.40.50.300 26 356 1.6E-81 T 28-03-2018 SMD44_RS03710 b40b561449eaccc1994fc739a334c857 361 Pfam PF00005 ABC transporter 57 207 1.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 Gene3D G3DSA:3.40.50.980 277 442 6.8E-23 T 28-03-2018 SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 Pfam PF00501 AMP-binding enzyme 111 531 1.6E-48 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 41 97 5.5E-13 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 Pfam PF13193 AMP-binding enzyme C-terminal domain 544 619 5.1E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 ProSitePatterns PS00455 Putative AMP-binding domain signature. 271 282 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 Gene3D G3DSA:3.40.50.980 94 276 1.5E-32 T 28-03-2018 SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 Gene3D G3DSA:2.30.38.10 448 526 9.8E-5 T 28-03-2018 SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 SUPERFAMILY SSF56801 41 633 7.98E-126 T 28-03-2018 SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 5 660 0.0 T 28-03-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 SMD44_RS06685 840a87615fa0f3257a97aa9c2e5cbfed 660 Gene3D G3DSA:3.30.300.30 528 632 1.5E-12 T 28-03-2018 SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 SMART SM00052 349 609 6.3E-103 T 28-03-2018 IPR001633 EAL domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 41 164 1.6E-13 T 28-03-2018 IPR000014 PAS domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 SUPERFAMILY SSF55785 36 148 2.09E-16 T 28-03-2018 IPR000014 PAS domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 SMART SM00267 157 339 1.7E-40 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 SUPERFAMILY SSF141868 355 614 2.35E-80 T 28-03-2018 IPR001633 EAL domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 Gene3D G3DSA:3.30.450.20 31 166 5.3E-24 T 28-03-2018 SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 Pfam PF00563 EAL domain 356 604 1.5E-64 T 28-03-2018 IPR001633 EAL domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 SMART SM00091 40 106 8.9E-6 T 28-03-2018 IPR000014 PAS domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 Gene3D G3DSA:3.20.20.450 347 619 4.8E-105 T 28-03-2018 IPR001633 EAL domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 Pfam PF08448 PAS fold 47 158 3.2E-10 T 28-03-2018 IPR013656 PAS fold-4 SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 Gene3D G3DSA:3.30.70.270 167 346 1.6E-53 T 28-03-2018 SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 165 337 4.1E-31 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 Pfam PF00990 Diguanylate cyclase, GGDEF domain 169 334 6.1E-38 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS15150 489ac000d5c46191894c1ab8392ffd48 619 SUPERFAMILY SSF55073 174 341 1.02E-36 T 28-03-2018 IPR029787 Nucleotide cyclase SMD44_RS41700 b515ee9a5f7788d56218ca6ae8b1aa71 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 9.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS41700 b515ee9a5f7788d56218ca6ae8b1aa71 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 9.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS41700 b515ee9a5f7788d56218ca6ae8b1aa71 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 9.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS41700 b515ee9a5f7788d56218ca6ae8b1aa71 212 SUPERFAMILY SSF46894 141 206 1.8E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS41700 b515ee9a5f7788d56218ca6ae8b1aa71 212 Gene3D G3DSA:1.10.10.10 8 212 9.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS41700 b515ee9a5f7788d56218ca6ae8b1aa71 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 205 1.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS41700 b515ee9a5f7788d56218ca6ae8b1aa71 212 SMART SM00421 152 209 1.3E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS07465 0e7b826690490304be6947137d1f05e0 202 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07465 0e7b826690490304be6947137d1f05e0 202 Pfam PF01174 SNO glutamine amidotransferase family 9 193 8.3E-61 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07465 0e7b826690490304be6947137d1f05e0 202 Gene3D G3DSA:3.40.50.880 5 201 3.3E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS07465 0e7b826690490304be6947137d1f05e0 202 SUPERFAMILY SSF52317 6 194 1.65E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS07465 0e7b826690490304be6947137d1f05e0 202 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 7 191 3.4E-84 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07465 0e7b826690490304be6947137d1f05e0 202 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 7 192 37.781 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07465 0e7b826690490304be6947137d1f05e0 202 PIRSF PIRSF005639 1 197 1.4E-75 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS04815 165e28d56bdf26f8765cc2fbda18f0dc 282 Gene3D G3DSA:2.140.10.30 14 279 9.1E-4 T 28-03-2018 SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 Pfam PF07690 Major Facilitator Superfamily 10 413 4.0E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 77 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 SUPERFAMILY SSF103473 3 189 7.19E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 SUPERFAMILY SSF103473 252 423 7.19E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 SUPERFAMILY SSF103473 460 486 7.19E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 Gene3D G3DSA:1.20.1250.20 1 192 1.6E-28 T 28-03-2018 SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 100 120 8.9E-9 T 28-03-2018 SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 154 8.9E-9 T 28-03-2018 SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 9 33 8.9E-9 T 28-03-2018 SMD44_RS34600 aae607dea928e2e8ce9172171341c7fe 510 Gene3D G3DSA:1.20.1250.20 263 498 5.6E-29 T 28-03-2018 SMD44_RS29860 d7066b1bb4832d57d0a6bd11874d26f0 192 SUPERFAMILY SSF55729 6 174 1.19E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS29860 d7066b1bb4832d57d0a6bd11874d26f0 192 Gene3D G3DSA:3.40.630.30 4 192 1.7E-29 T 28-03-2018 SMD44_RS29860 d7066b1bb4832d57d0a6bd11874d26f0 192 Pfam PF13302 Acetyltransferase (GNAT) domain 11 149 2.4E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS19815 155641adbf3ee7578418e3ed3e500dca 412 SMART SM00825 Beta-ketoacyl synthase 12 405 1.7E-15 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS19815 155641adbf3ee7578418e3ed3e500dca 412 Gene3D G3DSA:3.40.47.10 2 259 4.1E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19815 155641adbf3ee7578418e3ed3e500dca 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 246 9.6E-35 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS19815 155641adbf3ee7578418e3ed3e500dca 412 SUPERFAMILY SSF53901 219 407 1.07E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19815 155641adbf3ee7578418e3ed3e500dca 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 162 178 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS19815 155641adbf3ee7578418e3ed3e500dca 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 364 2.0E-31 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS19815 155641adbf3ee7578418e3ed3e500dca 412 SUPERFAMILY SSF53901 10 254 5.26E-50 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19815 155641adbf3ee7578418e3ed3e500dca 412 Gene3D G3DSA:3.40.47.10 261 410 2.1E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 SUPERFAMILY SSF51998 183 706 2.78E-180 T 28-03-2018 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 Pfam PF08343 Ribonucleotide reductase N-terminal 24 105 3.0E-28 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 107 179 4.2E-10 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 Pfam PF02867 Ribonucleotide reductase, barrel domain 184 701 4.8E-139 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 585 612 1.1E-30 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 495 1.1E-30 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 501 524 1.1E-30 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 434 457 1.1E-30 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 390 401 1.1E-30 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 259 278 1.1E-30 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 23 722 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 SUPERFAMILY SSF48168 23 182 4.19E-51 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 574 596 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 Gene3D G3DSA:3.20.70.20 86 709 4.8E-155 T 28-03-2018 SMD44_RS01080 bf460bdb0b302d1c8fee6c53c595f3a1 722 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 112 704 2.3E-153 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS14255 ad8f3bf85ff31fc29d52301e49118458 218 Gene3D G3DSA:3.40.30.10 67 179 2.9E-9 T 28-03-2018 SMD44_RS14255 ad8f3bf85ff31fc29d52301e49118458 218 Pfam PF01323 DSBA-like thioredoxin domain 15 176 5.5E-6 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD44_RS14255 ad8f3bf85ff31fc29d52301e49118458 218 SUPERFAMILY SSF52833 15 178 1.63E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS14255 ad8f3bf85ff31fc29d52301e49118458 218 Gene3D G3DSA:3.40.30.10 11 66 2.8E-11 T 28-03-2018 SMD44_RS26175 e17133c2bb959f21ab978da494b1d414 655 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 161 324 1.4E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS26175 e17133c2bb959f21ab978da494b1d414 655 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 483 649 2.3E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS26175 e17133c2bb959f21ab978da494b1d414 655 Gene3D G3DSA:1.10.3720.10 427 655 5.2E-29 T 28-03-2018 SMD44_RS26175 e17133c2bb959f21ab978da494b1d414 655 Gene3D G3DSA:1.10.3720.10 23 337 2.5E-28 T 28-03-2018 SMD44_RS26175 e17133c2bb959f21ab978da494b1d414 655 SUPERFAMILY SSF161098 141 323 2.75E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS26175 e17133c2bb959f21ab978da494b1d414 655 SUPERFAMILY SSF161098 461 644 5.36E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS07925 9f7a59116ed9e93aec2ae9127a34e600 247 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 35 104 9.6E-29 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD44_RS07925 9f7a59116ed9e93aec2ae9127a34e600 247 SUPERFAMILY SSF54364 33 106 4.18E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD44_RS07925 9f7a59116ed9e93aec2ae9127a34e600 247 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 29 198 29.528 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD44_RS07925 9f7a59116ed9e93aec2ae9127a34e600 247 Gene3D G3DSA:3.10.20.80 30 106 1.0E-30 T 28-03-2018 SMD44_RS07925 9f7a59116ed9e93aec2ae9127a34e600 247 SUPERFAMILY SSF55200 113 197 2.62E-31 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SMD44_RS07925 9f7a59116ed9e93aec2ae9127a34e600 247 Gene3D G3DSA:3.30.110.10 107 206 1.0E-33 T 28-03-2018 SMD44_RS07925 9f7a59116ed9e93aec2ae9127a34e600 247 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 35 198 1.8E-60 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD44_RS07925 9f7a59116ed9e93aec2ae9127a34e600 247 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 112 195 1.8E-33 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SMD44_RS12015 77b501493a10ef7d3956735d4a8eeba8 422 SUPERFAMILY SSF103473 18 400 1.44E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12015 77b501493a10ef7d3956735d4a8eeba8 422 Pfam PF05977 Transmembrane secretion effector 17 381 4.3E-26 T 28-03-2018 IPR010290 Transmembrane secretion effector SMD44_RS12015 77b501493a10ef7d3956735d4a8eeba8 422 Gene3D G3DSA:1.20.1250.20 216 416 1.7E-15 T 28-03-2018 SMD44_RS12015 77b501493a10ef7d3956735d4a8eeba8 422 Gene3D G3DSA:1.20.1250.20 15 211 5.3E-19 T 28-03-2018 SMD44_RS12225 3bcdca10449e3e52d174fec3cf584bb5 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 11 209 7.0E-76 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD44_RS12225 3bcdca10449e3e52d174fec3cf584bb5 211 Pfam PF01081 KDPG and KHG aldolase 10 202 4.6E-70 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD44_RS12225 3bcdca10449e3e52d174fec3cf584bb5 211 Gene3D G3DSA:3.20.20.70 9 211 1.0E-28 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS12225 3bcdca10449e3e52d174fec3cf584bb5 211 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 128 141 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD44_RS12225 3bcdca10449e3e52d174fec3cf584bb5 211 SUPERFAMILY SSF51569 11 208 2.01E-66 T 28-03-2018 SMD44_RS12225 3bcdca10449e3e52d174fec3cf584bb5 211 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 40 49 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 197 261 2.4E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 Pfam PF00672 HAMP domain 143 192 2.8E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 414 6.3E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 Gene3D G3DSA:3.30.565.10 264 415 2.6E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 SUPERFAMILY SSF47384 180 261 3.14E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 SMART SM00304 142 195 1.7E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 SMART SM00388 196 262 1.8E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 SUPERFAMILY SSF158472 143 192 2.75E-8 T 28-03-2018 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 Gene3D G3DSA:1.10.287.130 186 258 3.2E-12 T 28-03-2018 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 SUPERFAMILY SSF55874 253 415 6.81E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 395 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 219 233 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 370 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 414 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS31715 b8da489cdfd626f61403a2d10ac61eb8 415 SMART SM00387 304 415 1.7E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS36405 b570235ff87dcb481b7a270230fc2a3f 506 Pfam PF01266 FAD dependent oxidoreductase 40 390 7.0E-61 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS36405 b570235ff87dcb481b7a270230fc2a3f 506 Gene3D G3DSA:3.30.9.10 199 352 1.4E-31 T 28-03-2018 SMD44_RS36405 b570235ff87dcb481b7a270230fc2a3f 506 Gene3D G3DSA:3.50.50.60 6 117 1.6E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36405 b570235ff87dcb481b7a270230fc2a3f 506 Gene3D G3DSA:3.30.9.10 121 198 1.0E-5 T 28-03-2018 SMD44_RS36405 b570235ff87dcb481b7a270230fc2a3f 506 Pfam PF04324 BFD-like [2Fe-2S] binding domain 437 490 1.6E-12 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SMD44_RS36405 b570235ff87dcb481b7a270230fc2a3f 506 SUPERFAMILY SSF51905 354 399 2.12E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36405 b570235ff87dcb481b7a270230fc2a3f 506 SUPERFAMILY SSF51905 39 257 2.12E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36405 b570235ff87dcb481b7a270230fc2a3f 506 SUPERFAMILY SSF54373 258 353 1.44E-9 T 28-03-2018 SMD44_RS15430 3c52f9e616fd83e2201db0cbf04423ea 170 PIRSF PIRSF008757 14 170 2.3E-63 T 28-03-2018 IPR010371 Uncharacterised protein family UPF0303 SMD44_RS15430 3c52f9e616fd83e2201db0cbf04423ea 170 Hamap MF_00761 UPF0303 protein . 15 170 34.522 T 28-03-2018 IPR010371 Uncharacterised protein family UPF0303 SMD44_RS15430 3c52f9e616fd83e2201db0cbf04423ea 170 Pfam PF03928 Haem-degrading 37 165 8.6E-36 T 28-03-2018 IPR005624 Haem-degrading SMD44_RS15430 3c52f9e616fd83e2201db0cbf04423ea 170 SUPERFAMILY SSF143744 28 167 1.07E-28 T 28-03-2018 SMD44_RS18590 6478c62dc238026267bbfc7f29c115ba 290 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 8 280 38.66 T 28-03-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 SMD44_RS18590 6478c62dc238026267bbfc7f29c115ba 290 Pfam PF02621 Menaquinone biosynthesis 9 274 2.0E-82 T 28-03-2018 IPR003773 Menaquinone biosynthesis enzyme SMD44_RS18590 6478c62dc238026267bbfc7f29c115ba 290 Gene3D G3DSA:3.40.190.10 183 285 4.2E-14 T 28-03-2018 SMD44_RS18590 6478c62dc238026267bbfc7f29c115ba 290 Gene3D G3DSA:3.40.190.10 6 182 3.8E-80 T 28-03-2018 SMD44_RS18590 6478c62dc238026267bbfc7f29c115ba 290 SUPERFAMILY SSF53850 9 279 4.78E-79 T 28-03-2018 SMD44_RS06375 69df9d281c33c84a6884cd30bdbd13f6 532 SMART SM00108 1 113 1.7E-13 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS06375 69df9d281c33c84a6884cd30bdbd13f6 532 Pfam PF01453 D-mannose binding lectin 21 83 6.1E-12 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS06375 69df9d281c33c84a6884cd30bdbd13f6 532 Pfam PF01453 D-mannose binding lectin 58 111 5.2E-11 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS06375 69df9d281c33c84a6884cd30bdbd13f6 532 Pfam PF16158 Ig-like domain from next to BRCA1 gene 362 451 1.8E-7 T 28-03-2018 IPR032350 Next to BRCA1, central domain SMD44_RS06375 69df9d281c33c84a6884cd30bdbd13f6 532 Gene3D G3DSA:2.90.10.10 67 117 1.2E-11 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS06375 69df9d281c33c84a6884cd30bdbd13f6 532 Gene3D G3DSA:2.90.10.10 1 66 1.1E-12 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS06375 69df9d281c33c84a6884cd30bdbd13f6 532 Gene3D G3DSA:2.60.40.10 341 444 3.2E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS06375 69df9d281c33c84a6884cd30bdbd13f6 532 SUPERFAMILY SSF51110 13 111 4.32E-24 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS43810 ebf396c52ae9b42b6dbf7695eddb94eb 527 Pfam PF09299 Mu transposase, C-terminal 374 433 1.0E-13 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal SMD44_RS43810 ebf396c52ae9b42b6dbf7695eddb94eb 527 Pfam PF00665 Integrase core domain 158 281 8.9E-13 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SMD44_RS43810 ebf396c52ae9b42b6dbf7695eddb94eb 527 SUPERFAMILY SSF53098 159 364 2.17E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS43810 ebf396c52ae9b42b6dbf7695eddb94eb 527 Gene3D G3DSA:3.30.420.10 147 373 2.1E-32 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS43810 ebf396c52ae9b42b6dbf7695eddb94eb 527 Gene3D G3DSA:2.30.30.130 374 435 1.1E-14 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal SMD44_RS43810 ebf396c52ae9b42b6dbf7695eddb94eb 527 SUPERFAMILY SSF50610 371 435 1.7E-8 T 28-03-2018 IPR009004 Transposase, Mu, C-terminal SMD44_RS43810 ebf396c52ae9b42b6dbf7695eddb94eb 527 Gene3D G3DSA:1.10.260.40 27 114 0.013 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:1.10.1200.10 1153 1248 2.8E-19 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF47336 2837 2916 1.57E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.50.720 2542 2785 1.8E-47 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:1.10.1200.10 2823 2916 2.1E-18 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF53901 1246 1623 2.77E-106 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF51735 888 1124 7.76E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.47.10 1249 1512 1.0E-91 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF00698 Acyl transferase domain 88 394 7.0E-59 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF00698 Acyl transferase domain 1777 2081 3.3E-56 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.366.10 1949 2071 2.2E-27 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF52151 87 203 1.26E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF52151 263 370 1.26E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.50.720 888 1152 3.3E-48 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF55048 1897 1959 1.1E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.10.129.10 2134 2251 4.8E-9 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.10.129.10 442 564 1.2E-10 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00823 Phosphopantetheine attachment site 2844 2916 5.5E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00823 Phosphopantetheine attachment site 1157 1229 2.0E-30 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF51735 715 876 2.68E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF52151 1775 1892 8.37E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF52151 1952 2059 8.37E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1184 1199 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2578 2750 2.0E-52 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 889 1065 3.7E-56 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.30.70.250 1906 1948 2.7E-16 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.30.70.250 219 258 1.2E-17 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.366.10 1774 1905 1.3E-42 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.366.10 85 218 8.1E-42 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM01294 1158 1225 1.7E-5 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM01294 2849 2912 9.7E-6 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF14765 Polyketide synthase dehydratase 2129 2395 1.8E-56 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF14765 Polyketide synthase dehydratase 443 709 1.1E-54 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.366.10 259 381 8.1E-31 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1250 1500 3.0E-95 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2871 2886 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1778 2062 2.1E-112 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 89 376 2.1E-115 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1508 1624 4.7E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00825 Beta-ketoacyl synthase 1252 1677 1.8E-234 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1413 1429 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF08659 KR domain 2578 2748 4.5E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF08659 KR domain 890 1064 5.5E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF55048 208 270 4.97E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF51735 2577 2798 4.57E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1627 1738 5.4E-18 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.50.300 2369 2541 0.035 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.50.300 683 852 0.15 T 28-03-2018 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Gene3D G3DSA:3.40.47.10 1515 1675 5.0E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF51735 2402 2564 2.76E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF00550 Phosphopantetheine attachment site 2846 2912 2.0E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 Pfam PF00550 Phosphopantetheine attachment site 1160 1225 1.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00826 443 603 7.5E-87 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SMART SM00826 2129 2289 6.3E-87 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02280 e370cd3135d4cfbb281d0e0ab225ddcf 2996 SUPERFAMILY SSF47336 1152 1265 5.5E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS21575 894dfb6354d4f510b85116b2b83afcf7 292 Gene3D G3DSA:3.10.129.10 181 291 4.0E-4 T 28-03-2018 SMD44_RS21575 894dfb6354d4f510b85116b2b83afcf7 292 Pfam PF03756 A-factor biosynthesis hotdog domain 1 135 2.6E-20 T 28-03-2018 IPR005509 A-factor biosynthesis hotdog domain SMD44_RS21575 894dfb6354d4f510b85116b2b83afcf7 292 Pfam PF03756 A-factor biosynthesis hotdog domain 187 289 1.2E-14 T 28-03-2018 IPR005509 A-factor biosynthesis hotdog domain SMD44_RS19875 f7da955580af2c9ee0202ccf8b0d23f5 250 Gene3D G3DSA:1.25.40.10 104 245 1.1E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19875 f7da955580af2c9ee0202ccf8b0d23f5 250 Gene3D G3DSA:1.10.10.10 1 103 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19875 f7da955580af2c9ee0202ccf8b0d23f5 250 SUPERFAMILY SSF46894 9 100 2.3E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS19875 f7da955580af2c9ee0202ccf8b0d23f5 250 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 100 1.9E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19875 f7da955580af2c9ee0202ccf8b0d23f5 250 SMART SM01043 107 246 2.1E-36 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS19875 f7da955580af2c9ee0202ccf8b0d23f5 250 Pfam PF03704 Bacterial transcriptional activator domain 107 242 4.9E-37 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS19875 f7da955580af2c9ee0202ccf8b0d23f5 250 SUPERFAMILY SSF48452 102 243 2.42E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19875 f7da955580af2c9ee0202ccf8b0d23f5 250 SMART SM00862 21 100 1.1E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS13025 d0840370382c25cdf7a4d795eb93e665 132 Gene3D G3DSA:1.10.1660.10 1 56 2.2E-10 T 28-03-2018 SMD44_RS13025 d0840370382c25cdf7a4d795eb93e665 132 SUPERFAMILY SSF50331 67 129 4.37E-17 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMD44_RS13025 d0840370382c25cdf7a4d795eb93e665 132 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 67 129 2.2E-16 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 SMD44_RS13025 d0840370382c25cdf7a4d795eb93e665 132 Gene3D G3DSA:2.40.50.100 65 131 6.7E-21 T 28-03-2018 SMD44_RS13025 d0840370382c25cdf7a4d795eb93e665 132 Pfam PF03459 TOBE domain 67 129 5.6E-18 T 28-03-2018 IPR005116 Transport-associated OB, type 1 SMD44_RS13025 d0840370382c25cdf7a4d795eb93e665 132 SUPERFAMILY SSF46955 3 52 1.01E-9 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS13025 d0840370382c25cdf7a4d795eb93e665 132 Pfam PF12728 Helix-turn-helix domain 4 49 2.2E-9 T 28-03-2018 SMD44_RS00255 1c7936611ced0a9c4df797eb0532e7ce 292 SUPERFAMILY SSF50494 7 165 3.85E-14 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS00255 1c7936611ced0a9c4df797eb0532e7ce 292 Gene3D G3DSA:2.40.10.10 37 185 6.0E-5 T 28-03-2018 SMD44_RS00255 1c7936611ced0a9c4df797eb0532e7ce 292 Pfam PF13365 Trypsin-like peptidase domain 19 148 2.0E-6 T 28-03-2018 SMD44_RS00255 1c7936611ced0a9c4df797eb0532e7ce 292 Gene3D G3DSA:2.40.10.10 5 36 1.8E-5 T 28-03-2018 SMD44_RS12395 dbfc357a2487497a0d9a2b206e5709d4 395 SUPERFAMILY SSF48452 223 341 3.35E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12395 dbfc357a2487497a0d9a2b206e5709d4 395 Gene3D G3DSA:1.25.40.10 275 381 6.2E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12395 dbfc357a2487497a0d9a2b206e5709d4 395 Gene3D G3DSA:1.10.357.10 3 274 1.5E-10 T 28-03-2018 SMD44_RS12395 dbfc357a2487497a0d9a2b206e5709d4 395 SUPERFAMILY SSF47413 5 55 2.89E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 2.2E-237 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 2.4E-66 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 SUPERFAMILY SSF50615 27 98 3.4E-21 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 Gene3D G3DSA:2.40.30.20 6 86 2.8E-28 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 5.5E-46 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 4.5E-13 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 Gene3D G3DSA:1.20.150.20 385 512 1.5E-49 T 28-03-2018 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 SUPERFAMILY SSF47917 384 512 4.97E-45 T 28-03-2018 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 SUPERFAMILY SSF52540 100 382 8.51E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 Gene3D G3DSA:3.40.50.300 87 376 6.0E-106 T 28-03-2018 SMD44_RS28885 beeac6f0f40d06b083f0592998390434 530 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 513 47.992 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS25645 dbf79bbbb2240ad67a5f41dbefb7902d 174 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.334 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25645 dbf79bbbb2240ad67a5f41dbefb7902d 174 Pfam PF01196 Ribosomal protein L17 20 116 7.6E-38 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25645 dbf79bbbb2240ad67a5f41dbefb7902d 174 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 2.6E-41 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25645 dbf79bbbb2240ad67a5f41dbefb7902d 174 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25645 dbf79bbbb2240ad67a5f41dbefb7902d 174 Gene3D G3DSA:3.90.1030.10 1 117 3.1E-47 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25645 dbf79bbbb2240ad67a5f41dbefb7902d 174 SUPERFAMILY SSF64263 1 117 6.54E-47 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS35335 084dc3b092c21f3087a272fab1dfd420 341 Gene3D G3DSA:3.20.20.30 1 338 5.7E-61 T 28-03-2018 SMD44_RS35335 084dc3b092c21f3087a272fab1dfd420 341 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 3 323 5.9E-143 T 28-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c SMD44_RS35335 084dc3b092c21f3087a272fab1dfd420 341 Pfam PF00296 Luciferase-like monooxygenase 10 319 8.6E-73 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS35335 084dc3b092c21f3087a272fab1dfd420 341 SUPERFAMILY SSF51679 1 336 1.47E-60 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:1.10.1200.10 4686 4779 1.8E-19 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF47336 4701 4787 1.44E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF14765 Polyketide synthase dehydratase 3958 4215 7.6E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.10.129.10 3950 4076 1.3E-10 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1491 1506 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1814 1930 7.5E-46 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 7.1E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3323 3439 5.2E-46 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:1.10.1200.10 1454 1557 9.2E-21 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF52151 756 849 2.25E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF52151 571 694 2.25E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF52151 2269 2357 3.14E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF52151 2084 2207 3.14E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.366.10 2255 2367 5.5E-32 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.50.720 973 1170 0.039 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00550 Phosphopantetheine attachment site 1471 1532 2.9E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00550 Phosphopantetheine attachment site 2979 3040 4.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00550 Phosphopantetheine attachment site 4710 4775 8.1E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF55048 3716 3779 5.62E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF51735 4424 4674 2.91E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 537 9.6E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3442 3557 1.6E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1933 2051 1.5E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF53901 1554 1927 1.74E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.366.10 570 703 2.1E-42 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF51735 1178 1443 3.11E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1719 1735 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00823 Phosphopantetheine attachment site 4707 4779 5.0E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00823 Phosphopantetheine attachment site 1464 1536 9.3E-28 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00823 Phosphopantetheine attachment site 2972 3044 7.1E-28 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.50.720 4419 4666 8.1E-49 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.50.720 1173 1435 1.1E-52 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.50.720 2686 2943 1.7E-58 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.366.10 3774 3895 1.1E-21 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1556 1806 1.1E-95 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3065 3315 1.2E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.4E-88 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM01294 4708 4775 2.2E-6 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM01294 1465 1532 1.4E-5 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM01294 2973 3040 6.4E-6 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2999 3014 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.50.720 2481 2638 0.042 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF51735 4223 4406 2.76E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF51735 2692 2917 1.07E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF55048 2206 2268 3.4E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.30.70.250 2212 2254 7.5E-15 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.47.10 299 460 2.2E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.47.10 3330 3490 1.8E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.47.10 1821 1981 2.6E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3228 3244 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF51735 972 1169 7.32E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 574 861 1.2E-114 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3596 3887 2.6E-109 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2087 2374 3.6E-114 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.30.70.250 704 744 1.8E-17 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.30.70.250 3730 3773 3.1E-16 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF52151 3782 3878 7.32E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF52151 3593 3718 7.32E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.366.10 745 861 2.8E-30 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF08659 KR domain 1181 1359 4.7E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF08659 KR domain 2694 2868 5.9E-60 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF08659 KR domain 4428 4602 1.0E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF47336 1459 1571 1.44E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF101173 3 34 7.45E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF47336 2967 3080 1.28E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF08990 Erythronolide synthase docking 3 27 3.7E-11 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:1.10.1200.10 2954 3052 1.2E-18 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.366.10 3590 3729 2.6E-43 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.366.10 2080 2211 5.0E-44 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4734 4749 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF53901 3063 3437 1.23E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.47.10 1558 1818 4.8E-88 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.47.10 26 296 7.5E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Gene3D G3DSA:3.40.47.10 3058 3327 1.1E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4427 4603 7.7E-54 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2694 2870 8.3E-55 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1181 1360 1.4E-50 T 28-03-2018 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF51735 2485 2682 8.66E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF53901 31 407 2.22E-96 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00825 Beta-ketoacyl synthase 36 462 2.6E-219 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00825 Beta-ketoacyl synthase 1558 1983 6.4E-231 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00825 Beta-ketoacyl synthase 3067 3492 4.1E-224 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SMART SM00826 3951 4111 1.1E-74 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00698 Acyl transferase domain 2086 2389 4.4E-60 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00698 Acyl transferase domain 3594 3903 3.5E-80 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 Pfam PF00698 Acyl transferase domain 573 880 1.8E-58 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02300 88996b5e66597a58da439c5449bf86df 4855 SUPERFAMILY SSF55048 693 755 1.83E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS17940 1eb301d1bc433f0cac73288234e3f41c 215 Gene3D G3DSA:1.10.357.10 5 211 1.5E-24 T 28-03-2018 SMD44_RS17940 1eb301d1bc433f0cac73288234e3f41c 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 62 7.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS17940 1eb301d1bc433f0cac73288234e3f41c 215 SUPERFAMILY SSF46689 15 77 1.47E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS17940 1eb301d1bc433f0cac73288234e3f41c 215 SUPERFAMILY SSF48498 100 200 1.58E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS30055 84726d5e30e725c356eed606dc86bdda 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 2.7E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30055 84726d5e30e725c356eed606dc86bdda 205 Gene3D G3DSA:1.10.10.60 1 60 1.4E-16 T 28-03-2018 SMD44_RS30055 84726d5e30e725c356eed606dc86bdda 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30055 84726d5e30e725c356eed606dc86bdda 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30055 84726d5e30e725c356eed606dc86bdda 205 SUPERFAMILY SSF48498 86 198 4.45E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS30055 84726d5e30e725c356eed606dc86bdda 205 SUPERFAMILY SSF46689 8 91 1.6E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS30055 84726d5e30e725c356eed606dc86bdda 205 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 88 201 4.9E-22 T 28-03-2018 SMD44_RS30055 84726d5e30e725c356eed606dc86bdda 205 Gene3D G3DSA:1.10.357.10 61 200 2.1E-22 T 28-03-2018 SMD44_RS00370 c27a066fb8eafcf45c7159c6f8ef4e1c 396 Gene3D G3DSA:3.30.565.10 246 387 1.2E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS00370 c27a066fb8eafcf45c7159c6f8ef4e1c 396 Pfam PF07730 Histidine kinase 180 242 9.5E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS00370 c27a066fb8eafcf45c7159c6f8ef4e1c 396 SUPERFAMILY SSF55874 281 381 1.51E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS32555 e54f46ef92cc1f772605a6871e6f6e93 450 Pfam PF00069 Protein kinase domain 119 224 2.1E-15 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS32555 e54f46ef92cc1f772605a6871e6f6e93 450 SMART SM00220 20 303 3.1E-7 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS32555 e54f46ef92cc1f772605a6871e6f6e93 450 Gene3D G3DSA:1.10.510.10 13 317 5.1E-20 T 28-03-2018 SMD44_RS32555 e54f46ef92cc1f772605a6871e6f6e93 450 SUPERFAMILY SSF56112 15 237 4.1E-22 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.9E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 Gene3D G3DSA:3.40.190.10 91 173 2.8E-12 T 28-03-2018 SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 Gene3D G3DSA:3.40.190.10 174 267 5.9E-5 T 28-03-2018 SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 SUPERFAMILY SSF46785 2 83 5.44E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 Pfam PF03466 LysR substrate binding domain 101 293 2.9E-14 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 SUPERFAMILY SSF53850 101 294 6.16E-18 T 28-03-2018 SMD44_RS26260 9aa009d707940fe9a0e8e55fce6197b2 310 Gene3D G3DSA:1.10.10.10 1 83 5.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10845 15667f0e258f87622532f3fa83c9eca3 218 SUPERFAMILY SSF52317 10 216 1.7E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS10845 15667f0e258f87622532f3fa83c9eca3 218 Pfam PF00117 Glutamine amidotransferase class-I 14 208 4.6E-17 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS10845 15667f0e258f87622532f3fa83c9eca3 218 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 12 215 2.8E-60 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMD44_RS10845 15667f0e258f87622532f3fa83c9eca3 218 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 11 217 30.548 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMD44_RS10845 15667f0e258f87622532f3fa83c9eca3 218 PIRSF PIRSF000495 10 218 9.9E-65 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMD44_RS10845 15667f0e258f87622532f3fa83c9eca3 218 Gene3D G3DSA:3.40.50.880 6 218 2.8E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 Gene3D G3DSA:3.40.50.300 1 290 1.9E-50 T 28-03-2018 SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 SUPERFAMILY SSF52540 2 79 4.07E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 SUPERFAMILY SSF52540 128 232 4.07E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 SUPERFAMILY SSF52540 330 517 1.1E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 Pfam PF00005 ABC transporter 342 471 4.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 Pfam PF00005 ABC transporter 18 187 5.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 SMART SM00382 350 515 3.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 SMART SM00382 26 232 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 Gene3D G3DSA:3.40.50.300 291 523 3.0E-49 T 28-03-2018 SMD44_RS09550 6ae538609eaa6e3c7ff32ae02a8edb7c 532 Pfam PF12848 ABC transporter 230 306 1.2E-6 T 28-03-2018 IPR032781 ABC-transporter extension domain SMD44_RS20965 ef99ee0701238bbf8629edcc9b4414cd 445 PIRSF PIRSF006603 4 445 4.8E-66 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD44_RS20965 ef99ee0701238bbf8629edcc9b4414cd 445 Pfam PF01554 MatE 25 184 3.4E-29 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD44_RS20965 ef99ee0701238bbf8629edcc9b4414cd 445 Pfam PF01554 MatE 246 397 2.9E-20 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD44_RS20965 ef99ee0701238bbf8629edcc9b4414cd 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 415 5.6E-105 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD44_RS16300 922509697703eccac56c6c71e05f0402 225 SUPERFAMILY SSF52172 4 177 3.13E-43 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS16300 922509697703eccac56c6c71e05f0402 225 Gene3D G3DSA:1.10.10.10 121 224 2.2E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16300 922509697703eccac56c6c71e05f0402 225 Gene3D G3DSA:3.40.50.2300 2 120 6.8E-37 T 28-03-2018 SMD44_RS16300 922509697703eccac56c6c71e05f0402 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 3.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS16300 922509697703eccac56c6c71e05f0402 225 SMART SM00448 3 113 2.3E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16300 922509697703eccac56c6c71e05f0402 225 Pfam PF00072 Response regulator receiver domain 5 114 7.0E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16300 922509697703eccac56c6c71e05f0402 225 SMART SM00862 146 222 5.9E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS13640 fa3636c67f3b907ad9ae1e43ee7a89fc 541 Gene3D G3DSA:3.90.76.10 72 179 3.5E-24 T 28-03-2018 SMD44_RS13640 fa3636c67f3b907ad9ae1e43ee7a89fc 541 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 12 34 2.8E-6 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SMD44_RS13640 fa3636c67f3b907ad9ae1e43ee7a89fc 541 Gene3D G3DSA:3.40.190.10 180 313 7.8E-30 T 28-03-2018 SMD44_RS13640 fa3636c67f3b907ad9ae1e43ee7a89fc 541 Gene3D G3DSA:3.10.105.10 314 512 6.3E-39 T 28-03-2018 SMD44_RS13640 fa3636c67f3b907ad9ae1e43ee7a89fc 541 PIRSF PIRSF002741 17 540 2.9E-73 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS13640 fa3636c67f3b907ad9ae1e43ee7a89fc 541 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 12 31 1.7E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SMD44_RS13640 fa3636c67f3b907ad9ae1e43ee7a89fc 541 SUPERFAMILY SSF53850 49 540 3.44E-98 T 28-03-2018 SMD44_RS13640 fa3636c67f3b907ad9ae1e43ee7a89fc 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 450 4.2E-70 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 283 2.6E-91 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.6E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.6E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 1.6E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.6E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 SUPERFAMILY SSF55920 6 284 4.71E-87 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 Pfam PF00557 Metallopeptidase family M24 48 276 7.5E-54 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 Gene3D G3DSA:3.90.230.10 39 285 2.2E-88 T 28-03-2018 SMD44_RS12025 1e26cad5c6df1038afe8c4f6a673aec5 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.33 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 SUPERFAMILY SSF52518 4 363 2.01E-69 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 SUPERFAMILY SSF52518 390 582 5.06E-22 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 Pfam PF09364 XFP N-terminal domain 3 378 3.4E-175 T 28-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 Gene3D G3DSA:3.40.50.920 600 784 2.0E-79 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 PIRSF PIRSF017245 1 784 0.0 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 ProSitePatterns PS60003 Phosphoketolase signature 2. 150 168 - T 28-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 393 567 2.4E-84 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 ProSitePatterns PS60002 Phosphoketolase signature 1. 137 143 - T 28-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 Gene3D G3DSA:3.40.50.970 1 372 1.6E-84 T 28-03-2018 SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 Pfam PF09363 XFP C-terminal domain 580 782 9.0E-87 T 28-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 Hamap MF_01403 Probable phosphoketolase. 1 784 39.674 T 28-03-2018 IPR023962 Probable phosphoketolase SMD44_RS03635 094526da51e9b5fa369c4de41a94d2a2 784 Gene3D G3DSA:3.40.50.970 381 594 1.6E-29 T 28-03-2018 SMD44_RS15515 0215925adc2023ad9286e4fca9525a3c 70 Pfam PF04149 Domain of unknown function (DUF397) 12 64 1.5E-17 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 Gene3D G3DSA:1.10.10.10 1 167 1.0E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 3.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 3.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 3.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 3.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 ProSitePatterns PS01117 MarR-type HTH domain signature. 86 120 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 SMART SM00347 47 147 5.3E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 Pfam PF01047 MarR family 56 112 4.7E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS09720 57ebfbe0458a5809421dfa19f71e2f18 180 SUPERFAMILY SSF46785 27 161 9.38E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2411 2426 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF47336 919 992 7.2E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:2.30.38.10 4326 4406 2.4E-20 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:2.30.38.10 1796 1877 1.7E-21 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF08242 Methyltransferase domain 523 622 6.6E-12 T 28-03-2018 IPR013217 Methyltransferase type 12 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF08242 Methyltransferase domain 1999 2098 2.7E-12 T 28-03-2018 IPR013217 Methyltransferase type 12 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF53335 483 628 8.82E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4149 4160 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF52777 1013 1191 1.33E-47 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00975 Thioesterase domain 4613 4829 1.4E-25 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF53335 1938 2108 9.28E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF56801 2324 2400 1.44E-149 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF56801 1450 1937 1.44E-149 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:1.10.1200.10 930 996 3.4E-23 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF56801 2902 3456 8.37E-148 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00668 Condensation domain 1012 1471 3.3E-98 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00668 Condensation domain 2473 2922 6.2E-94 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00668 Condensation domain 3547 3986 4.4E-79 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00501 AMP-binding enzyme 2944 3337 3.4E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00501 AMP-binding enzyme 1490 1883 1.2E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00501 AMP-binding enzyme 4007 4413 4.0E-80 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00501 AMP-binding enzyme 50 400 5.2E-76 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1635 1646 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:1.10.1200.10 2381 2453 3.4E-24 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:1.10.1200.10 4531 4596 3.6E-16 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF47336 4519 4591 4.45E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF52777 2474 2648 1.11E-49 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SMART SM00824 Thioesterase 4615 4836 9.0E-9 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.30.300.30 3332 3448 3.9E-38 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.30.300.30 4408 4530 8.2E-32 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.30.300.30 821 929 3.7E-18 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.30.300.30 1879 1987 3.6E-14 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SMART SM00823 Phosphopantetheine attachment site 926 995 7.0E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SMART SM00823 Phosphopantetheine attachment site 4523 4594 4.4E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SMART SM00823 Phosphopantetheine attachment site 2387 2456 1.9E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SMART SM00823 Phosphopantetheine attachment site 3443 3511 4.8E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF52777 3728 3969 2.11E-45 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF52777 3546 3743 3.78E-40 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF47336 2380 2453 3.53E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.30.300.30 394 515 2.2E-19 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 ProSitePatterns PS00012 Phosphopantetheine attachment site. 950 965 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF56801 3964 4536 1.24E-132 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF56801 50 454 1.01E-124 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF56801 863 939 1.01E-124 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00550 Phosphopantetheine attachment site 929 990 5.1E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00550 Phosphopantetheine attachment site 4528 4590 7.5E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00550 Phosphopantetheine attachment site 3445 3505 1.9E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF00550 Phosphopantetheine attachment site 2389 2451 9.4E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.150 1988 2283 6.7E-22 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.980 1641 1795 8.0E-37 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.980 4155 4304 7.8E-29 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.980 151 299 8.9E-33 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.980 3095 3244 1.8E-32 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.150 516 809 9.9E-24 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.30.559.10 3538 3745 2.7E-36 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.30.559.10 997 1222 4.9E-47 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.30.559.10 2454 2677 4.4E-43 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:2.30.38.10 3246 3327 4.0E-23 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 50 424 6.0E-118 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4026 4437 1.1E-115 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2964 3361 2.9E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1511 1908 6.4E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:1.10.1200.10 3449 3519 8.6E-21 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF52777 2661 2910 7.34E-56 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.980 2934 3094 1.0E-44 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.980 40 150 1.1E-25 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.980 1481 1640 3.5E-45 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.980 3997 4154 1.4E-44 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:2.30.38.10 300 392 2.6E-20 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF13193 AMP-binding enzyme C-terminal domain 4421 4497 1.7E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF13193 AMP-binding enzyme C-terminal domain 408 450 4.1E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Pfam PF13193 AMP-binding enzyme C-terminal domain 3345 3418 7.3E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 Gene3D G3DSA:3.40.50.1820 4597 4837 1.1E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF52777 1205 1458 2.45E-60 T 28-03-2018 SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF47336 3435 3505 1.06E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3088 3099 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3467 3482 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS38735 cf4830aa8796d51583b7bdad91435ee3 4867 SUPERFAMILY SSF53474 4592 4836 1.16E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS12425 262cee11b5cf219565783c6f59df53ed 411 SUPERFAMILY SSF48239 250 312 1.1E-22 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS12425 262cee11b5cf219565783c6f59df53ed 411 SUPERFAMILY SSF48239 57 172 1.1E-22 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS12425 262cee11b5cf219565783c6f59df53ed 411 Gene3D G3DSA:1.50.10.20 211 323 0.0083 T 28-03-2018 SMD44_RS12425 262cee11b5cf219565783c6f59df53ed 411 Gene3D G3DSA:1.50.10.20 117 199 2.1E-15 T 28-03-2018 SMD44_RS12425 262cee11b5cf219565783c6f59df53ed 411 Gene3D G3DSA:1.50.10.20 5 116 1.1E-10 T 28-03-2018 SMD44_RS12425 262cee11b5cf219565783c6f59df53ed 411 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 73 120 0.11 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 SMD44_RS12425 262cee11b5cf219565783c6f59df53ed 411 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 127 168 1.1E-6 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 PIRSF PIRSF000171 1 608 9.7E-38 T 28-03-2018 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 SUPERFAMILY SSF56425 243 389 6.58E-34 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 394 416 3.6E-7 T 28-03-2018 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.6E-7 T 28-03-2018 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 Gene3D G3DSA:1.20.58.100 456 577 2.8E-31 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 Pfam PF00890 FAD binding domain 10 430 6.8E-92 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 Gene3D G3DSA:3.50.50.60 1 342 1.4E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 Pfam PF02910 Fumarate reductase flavoprotein C-term 491 588 1.0E-23 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 Gene3D G3DSA:3.50.50.60 343 446 2.2E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 SUPERFAMILY SSF51905 3 270 1.24E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 SUPERFAMILY SSF51905 393 470 1.24E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS27660 32822b7b537738b75bf28154a50e37cd 642 SUPERFAMILY SSF46977 485 639 2.75E-39 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS07880 d8224cddade06fe4ef7c086a8511cc3b 180 Pfam PF00293 NUDIX domain 40 152 5.1E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS07880 d8224cddade06fe4ef7c086a8511cc3b 180 Gene3D G3DSA:3.90.79.10 1 179 1.3E-32 T 28-03-2018 SMD44_RS07880 d8224cddade06fe4ef7c086a8511cc3b 180 SUPERFAMILY SSF55811 3 174 1.76E-37 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS07880 d8224cddade06fe4ef7c086a8511cc3b 180 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS33350 ade9d9b46f2753dac771ac5a20defcc2 190 Gene3D G3DSA:1.10.3330.10 27 187 2.9E-45 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMD44_RS33350 ade9d9b46f2753dac771ac5a20defcc2 190 Pfam PF09349 OHCU decarboxylase 33 182 2.4E-36 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMD44_RS33350 ade9d9b46f2753dac771ac5a20defcc2 190 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 32 184 2.9E-58 T 28-03-2018 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 SMD44_RS33350 ade9d9b46f2753dac771ac5a20defcc2 190 SUPERFAMILY SSF158694 28 185 3.27E-40 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMD44_RS34330 3fa39ef3fa4be130951962c8c7fdc99f 367 SUPERFAMILY SSF51604 115 366 2.23E-49 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS34330 3fa39ef3fa4be130951962c8c7fdc99f 367 Gene3D G3DSA:3.30.390.10 9 133 1.3E-27 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS34330 3fa39ef3fa4be130951962c8c7fdc99f 367 Gene3D G3DSA:3.20.20.120 134 357 5.9E-48 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS34330 3fa39ef3fa4be130951962c8c7fdc99f 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 38 127 4.8E-10 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMD44_RS34330 3fa39ef3fa4be130951962c8c7fdc99f 367 SUPERFAMILY SSF54826 17 132 4.72E-23 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS34330 3fa39ef3fa4be130951962c8c7fdc99f 367 Pfam PF13378 Enolase C-terminal domain-like 149 357 3.3E-46 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS34330 3fa39ef3fa4be130951962c8c7fdc99f 367 SMART SM00922 146 247 2.6E-14 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMD44_RS34330 3fa39ef3fa4be130951962c8c7fdc99f 367 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 102 127 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMD44_RS36740 5ad462562ca0527c235845f8c6a81233 383 Pfam PF04138 GtrA-like protein 240 354 5.6E-14 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMD44_RS36740 5ad462562ca0527c235845f8c6a81233 383 Gene3D G3DSA:3.90.550.10 1 231 9.8E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS36740 5ad462562ca0527c235845f8c6a81233 383 SUPERFAMILY SSF53448 1 173 3.59E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS36740 5ad462562ca0527c235845f8c6a81233 383 Pfam PF00535 Glycosyl transferase family 2 1 168 4.7E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 Gene3D G3DSA:3.20.20.70 379 730 6.7E-117 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 Gene3D G3DSA:3.50.50.60 1 378 9.8E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 5.9E-5 T 28-03-2018 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 127 142 5.9E-5 T 28-03-2018 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 263 278 5.9E-5 T 28-03-2018 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 387 720 9.7E-62 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 Pfam PF13450 NAD(P)-binding Rossmann-like domain 3 32 6.6E-5 T 28-03-2018 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 SUPERFAMILY SSF51905 250 339 4.89E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 SUPERFAMILY SSF51905 1 148 4.89E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 SUPERFAMILY SSF51395 383 726 5.64E-116 T 28-03-2018 SMD44_RS32160 1784bf858f95984f9de4e8c50dcf511e 759 Pfam PF01494 FAD binding domain 129 323 2.2E-13 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 SUPERFAMILY SSF53623 92 310 1.44E-57 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 9 451 1.7E-138 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 Pfam PF01225 Mur ligase family, catalytic domain 9 104 4.7E-27 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 SUPERFAMILY SSF53244 312 455 4.12E-42 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 460 38.135 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 Gene3D G3DSA:3.90.190.20 314 460 6.0E-38 T 28-03-2018 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 Pfam PF08245 Mur ligase middle domain 111 292 1.6E-23 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 Gene3D G3DSA:3.40.50.720 4 94 3.8E-19 T 28-03-2018 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 Gene3D G3DSA:3.40.1190.10 95 313 9.9E-46 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 SUPERFAMILY SSF51984 6 94 4.58E-26 T 28-03-2018 SMD44_RS32510 5cd0555f5d064688a10455d94a54bf0e 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 399 1.5E-20 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 Pfam PF04055 Radical SAM superfamily 542 702 2.5E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 Pfam PF04055 Radical SAM superfamily 82 264 2.4E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 Hamap MF_01611 FO synthase subunit 1 [cofG]. 74 405 49.752 T 28-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 75 403 1.0E-141 T 28-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 Hamap MF_01612 FO synthase subunit 2 [cofH]. 485 845 48.488 T 28-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 SUPERFAMILY SSF102114 34 379 3.14E-35 T 28-03-2018 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 499 844 2.4E-160 T 28-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 SUPERFAMILY SSF102114 497 808 3.53E-49 T 28-03-2018 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 534 842 5.8E-108 T 28-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 SMART SM00729 78 315 2.4E-7 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 Gene3D G3DSA:3.20.20.70 13 388 7.5E-33 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS17800 6f17bc527a82cf626b6d0285c17b0c71 868 Gene3D G3DSA:3.20.20.70 479 846 3.8E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS40410 6c316955f479be26cc58df9f81c51d20 367 Pfam PF13407 Periplasmic binding protein domain 42 321 5.4E-66 T 28-03-2018 IPR025997 Periplasmic binding protein SMD44_RS40410 6c316955f479be26cc58df9f81c51d20 367 Gene3D G3DSA:3.40.50.2300 40 145 2.3E-19 T 28-03-2018 SMD44_RS40410 6c316955f479be26cc58df9f81c51d20 367 Gene3D G3DSA:3.40.50.2300 146 363 3.4E-33 T 28-03-2018 SMD44_RS40410 6c316955f479be26cc58df9f81c51d20 367 SUPERFAMILY SSF53822 38 353 2.16E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 Gene3D G3DSA:3.30.460.10 236 367 1.9E-22 T 28-03-2018 SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 Pfam PF13328 HD domain 72 219 8.2E-40 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 Pfam PF02824 TGS domain 436 494 1.7E-13 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 SUPERFAMILY SSF81301 236 381 9.48E-33 T 28-03-2018 SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 SUPERFAMILY SSF109604 54 235 5.34E-62 T 28-03-2018 SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 SMART SM00471 87 197 3.9E-11 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 SUPERFAMILY SSF81271 436 494 4.14E-8 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 Pfam PF13291 ACT domain 633 706 1.5E-11 T 28-03-2018 IPR002912 ACT domain SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 Gene3D G3DSA:3.30.70.260 627 714 1.3E-5 T 28-03-2018 SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 SUPERFAMILY SSF55021 632 707 2.14E-5 T 28-03-2018 SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 Gene3D G3DSA:3.10.20.30 429 501 4.4E-19 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 SMART SM00954 279 387 6.9E-25 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 SMD44_RS31375 3dff564ab3f5c8924d4f9f55133ddea0 715 Pfam PF04607 Region found in RelA / SpoT proteins 307 381 3.8E-13 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 Pfam PF06483 Chitinase C 534 705 2.1E-81 T 28-03-2018 IPR009470 Chitinase, C-terminal KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 SUPERFAMILY SSF54556 382 495 2.52E-12 T 28-03-2018 IPR029070 Chitinase insertion domain SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 Gene3D G3DSA:2.10.10.20 713 774 1.6E-14 T 28-03-2018 SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 SMART SM00495 726 771 7.9E-10 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 Pfam PF00704 Glycosyl hydrolases family 18 73 525 7.6E-85 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 ProSitePatterns PS01095 Chitinases family 18 active site. 224 232 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 SUPERFAMILY SSF51445 66 382 2.29E-79 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 SUPERFAMILY SSF51445 497 529 2.29E-79 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 SMART SM00636 72 525 1.5E-125 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 SUPERFAMILY SSF51055 722 774 7.26E-13 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD44_RS07040 bea657270d060d8642a10a1194d8efbf 774 Gene3D G3DSA:3.20.20.80 18 557 2.8E-88 T 28-03-2018 SMD44_RS16815 24ed8818ed5ac2d8a1898915e8cc133e 220 Pfam PF13624 SurA N-terminal domain 4 153 5.7E-12 T 28-03-2018 SMD44_RS16815 24ed8818ed5ac2d8a1898915e8cc133e 220 SUPERFAMILY SSF109998 32 160 1.96E-15 T 28-03-2018 IPR027304 Trigger factor/SurA domain SMD44_RS16815 24ed8818ed5ac2d8a1898915e8cc133e 220 Gene3D G3DSA:1.10.4030.10 27 158 2.1E-15 T 28-03-2018 SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 SUPERFAMILY SSF51735 19 259 2.38E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 Gene3D G3DSA:3.40.50.720 68 262 8.7E-50 T 28-03-2018 SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 Gene3D G3DSA:3.40.50.720 13 67 3.7E-9 T 28-03-2018 SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.7E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 1.7E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.7E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.7E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 1.7E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02180 02650282f7797536e2474ed09ea164d2 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 31 259 2.4E-54 T 28-03-2018 SMD44_RS22035 ad6b885897b82a704b50c4ac7c0e8126 251 Gene3D G3DSA:1.10.357.10 89 251 9.3E-31 T 28-03-2018 SMD44_RS22035 ad6b885897b82a704b50c4ac7c0e8126 251 SUPERFAMILY SSF46689 27 92 4.1E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS22035 ad6b885897b82a704b50c4ac7c0e8126 251 SUPERFAMILY SSF48498 102 250 1.22E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS22035 ad6b885897b82a704b50c4ac7c0e8126 251 Gene3D G3DSA:1.10.10.60 3 88 1.1E-16 T 28-03-2018 SMD44_RS22035 ad6b885897b82a704b50c4ac7c0e8126 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 82 2.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS22035 ad6b885897b82a704b50c4ac7c0e8126 251 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 100 248 2.2E-15 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS22035 ad6b885897b82a704b50c4ac7c0e8126 251 ProSitePatterns PS01081 TetR-type HTH domain signature. 50 81 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS12005 2a027abf405dc4cd3631bc2ea4b877aa 367 Gene3D G3DSA:2.120.10.10 6 367 1.2E-77 T 28-03-2018 SMD44_RS12005 2a027abf405dc4cd3631bc2ea4b877aa 367 SUPERFAMILY SSF50939 16 366 2.38E-89 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD44_RS12005 2a027abf405dc4cd3631bc2ea4b877aa 367 Pfam PF13088 BNR repeat-like domain 39 338 1.1E-34 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD44_RS31770 ce68f6b1d3d6d06c081fde08da816af4 180 SMART SM00862 99 172 9.3E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS31770 ce68f6b1d3d6d06c081fde08da816af4 180 Gene3D G3DSA:1.10.10.10 61 179 4.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31770 ce68f6b1d3d6d06c081fde08da816af4 180 SUPERFAMILY SSF46894 93 174 3.4E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS31770 ce68f6b1d3d6d06c081fde08da816af4 180 Pfam PF00486 Transcriptional regulatory protein, C terminal 100 172 1.2E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 Gene3D G3DSA:2.60.260.20 170 253 1.6E-17 T 28-03-2018 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 SUPERFAMILY SSF49493 116 149 2.22E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 SUPERFAMILY SSF49493 214 257 2.22E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 Gene3D G3DSA:2.60.260.20 111 169 8.9E-9 T 28-03-2018 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 SUPERFAMILY SSF57938 131 211 4.19E-18 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 Gene3D G3DSA:2.60.260.20 255 366 2.5E-28 T 28-03-2018 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 28-03-2018 IPR018253 DnaJ domain, conserved site SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 350 2.6E-119 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 Gene3D G3DSA:1.10.287.110 1 110 1.8E-34 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 PRINTS PR00625 DnaJ domain signature 6 24 2.1E-24 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 PRINTS PR00625 DnaJ domain signature 24 39 2.1E-24 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 PRINTS PR00625 DnaJ domain signature 60 79 2.1E-24 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 PRINTS PR00625 DnaJ domain signature 40 60 2.1E-24 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 Pfam PF00684 DnaJ central domain 144 208 1.9E-12 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 SUPERFAMILY SSF46565 3 100 2.22E-32 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 SUPERFAMILY SSF49493 259 345 1.44E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 Pfam PF00226 DnaJ domain 4 65 1.5E-25 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 SMART SM00271 3 60 1.3E-30 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 Pfam PF01556 DnaJ C terminal domain 119 334 1.9E-39 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal SMD44_RS13795 c603c00c3304c9330a7520e1811264d7 379 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 375 38.074 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMD44_RS19800 74849e8d7fcf2310b8519c6720e8db8f 399 SUPERFAMILY SSF103473 3 375 4.32E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS19800 74849e8d7fcf2310b8519c6720e8db8f 399 Gene3D G3DSA:1.20.1250.20 3 187 3.9E-29 T 28-03-2018 SMD44_RS19800 74849e8d7fcf2310b8519c6720e8db8f 399 Pfam PF07690 Major Facilitator Superfamily 9 315 8.0E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS19800 74849e8d7fcf2310b8519c6720e8db8f 399 Gene3D G3DSA:1.20.1250.20 190 377 9.2E-19 T 28-03-2018 SMD44_RS26805 59010b8344114d032b3b02d859f0d6d6 446 Pfam PF07690 Major Facilitator Superfamily 61 368 3.8E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS26805 59010b8344114d032b3b02d859f0d6d6 446 SUPERFAMILY SSF103473 40 430 7.72E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26805 59010b8344114d032b3b02d859f0d6d6 446 Gene3D G3DSA:1.20.1250.20 244 434 3.9E-13 T 28-03-2018 SMD44_RS26805 59010b8344114d032b3b02d859f0d6d6 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 111 127 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS26805 59010b8344114d032b3b02d859f0d6d6 446 Gene3D G3DSA:1.20.1250.20 43 239 2.3E-30 T 28-03-2018 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 372 43.317 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 260 5.1E-90 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 Gene3D G3DSA:3.30.1360.120 137 238 2.6E-28 T 28-03-2018 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 Gene3D G3DSA:3.30.1360.120 5 136 2.7E-31 T 28-03-2018 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 Gene3D G3DSA:2.40.30.110 290 374 5.1E-26 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 SUPERFAMILY SSF103025 6 283 7.22E-93 T 28-03-2018 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 272 366 1.5E-22 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 7 372 4.6E-104 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 Gene3D G3DSA:4.10.1250.10 239 285 6.9E-16 T 28-03-2018 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 PIRSF PIRSF006487 1 374 4.5E-96 T 28-03-2018 SMD44_RS29665 c5b48ead6eeb515638f1a5d7f9f20a41 374 SUPERFAMILY SSF101790 286 373 3.92E-24 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain SMD44_RS26890 317adb90106bdec44db2ab73a00d6c46 299 Pfam PF00171 Aldehyde dehydrogenase family 25 256 2.6E-39 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS26890 317adb90106bdec44db2ab73a00d6c46 299 Gene3D G3DSA:3.40.605.10 2 257 8.4E-56 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS26890 317adb90106bdec44db2ab73a00d6c46 299 SUPERFAMILY SSF53720 7 270 3.8E-45 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS00270 f1aa3a35dee8d4c8b3a0aac16dca1e50 354 PIRSF PIRSF000138 1 353 1.3E-122 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 SMD44_RS00270 f1aa3a35dee8d4c8b3a0aac16dca1e50 354 SUPERFAMILY SSF51395 2 350 3.42E-92 T 28-03-2018 SMD44_RS00270 f1aa3a35dee8d4c8b3a0aac16dca1e50 354 Gene3D G3DSA:3.20.20.70 1 352 8.0E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS00270 f1aa3a35dee8d4c8b3a0aac16dca1e50 354 Pfam PF01070 FMN-dependent dehydrogenase 10 351 9.4E-122 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 Gene3D G3DSA:3.40.50.300 723 963 1.2E-66 T 28-03-2018 SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 Pfam PF00005 ABC transporter 744 891 4.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 SUPERFAMILY SSF52540 721 960 1.41E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 SMART SM00382 753 929 9.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 TIGRFAM TIGR03797 NHLM_micro_ABC2: NHLM bacteriocin system ABC transporter, ATP-binding protein 279 961 8.3E-268 T 28-03-2018 IPR022515 NHPM bacteriocin system ABC transporter, ATP-binding protein SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 ProSitePatterns PS00211 ABC transporters family signature. 863 877 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 Pfam PF00664 ABC transporter transmembrane region 419 682 3.5E-19 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 Gene3D G3DSA:1.20.1560.10 397 717 5.7E-27 T 28-03-2018 SMD44_RS38245 e030ad7ade1057ca3c9b63187c694e56 964 SUPERFAMILY SSF90123 407 693 1.83E-37 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS10070 389153e3d6068e2d8f15d0ddb2403a4e 372 Gene3D G3DSA:3.20.20.70 1 361 4.2E-131 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS10070 389153e3d6068e2d8f15d0ddb2403a4e 372 SUPERFAMILY SSF51569 2 359 1.95E-76 T 28-03-2018 SMD44_RS10070 389153e3d6068e2d8f15d0ddb2403a4e 372 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 15 359 3.3E-82 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SMD44_RS10070 389153e3d6068e2d8f15d0ddb2403a4e 372 PIRSF PIRSF036915 1 372 1.5E-177 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD44_RS10070 389153e3d6068e2d8f15d0ddb2403a4e 372 Hamap MF_00493 Transaldolase [tal]. 1 370 160.815 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD44_RS10070 389153e3d6068e2d8f15d0ddb2403a4e 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 2.8E-132 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD44_RS10070 389153e3d6068e2d8f15d0ddb2403a4e 372 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.30.70.250 2200 2240 1.8E-16 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.30.70.250 3913 3953 1.8E-17 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.30.70.250 691 731 2.3E-16 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.366.10 732 841 4.3E-32 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1704 1720 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF08659 KR domain 1167 1345 4.2E-63 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF08659 KR domain 2879 3054 1.5E-57 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00825 Beta-ketoacyl synthase 1543 1969 1.6E-227 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00825 Beta-ketoacyl synthase 36 461 3.4E-231 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00825 Beta-ketoacyl synthase 3253 3678 2.1E-227 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00823 Phosphopantetheine attachment site 3160 3232 1.4E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00823 Phosphopantetheine attachment site 1450 1522 5.3E-28 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF00550 Phosphopantetheine attachment site 3163 3228 1.4E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF00550 Phosphopantetheine attachment site 1457 1518 6.1E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF55048 680 742 2.49E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.366.10 3779 3912 2.8E-42 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.366.10 557 690 9.2E-43 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.366.10 2066 2199 1.3E-44 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM01294 1451 1518 6.7E-6 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM01294 3169 3228 9.5E-5 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.10.129.10 2428 2545 6.8E-4 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF53901 32 405 3.11E-105 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF51735 957 1155 2.76E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF52151 2067 2184 1.54E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF52151 2244 2362 1.54E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2879 3055 6.0E-58 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1167 1346 7.0E-59 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3187 3202 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF53901 1537 1914 2.6E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00826 2424 2587 1.8E-75 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.366.10 3954 4079 2.8E-29 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.366.10 2241 2367 8.9E-29 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF51735 2703 2867 1.5E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF101173 3 34 7.85E-5 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF53901 3247 3623 5.51E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF47336 1445 1556 4.84E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 7.7E-96 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1541 1791 5.3E-95 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3251 3501 1.3E-92 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF52151 743 830 3.14E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF52151 559 681 3.14E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF00698 Acyl transferase domain 2069 2376 7.8E-59 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF00698 Acyl transferase domain 560 867 1.1E-56 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF00698 Acyl transferase domain 3782 4089 4.2E-57 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF14765 Polyketide synthase dehydratase 2424 2692 6.6E-49 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.47.10 1806 1967 1.2E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.47.10 299 459 7.9E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.47.10 3516 3676 2.2E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3628 3746 3.7E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 524 5.0E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1919 2033 7.7E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3783 4070 2.0E-111 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2070 2357 1.8E-115 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 561 848 1.3E-110 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF08990 Erythronolide synthase docking 2 27 2.2E-11 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF47336 3156 3266 2.09E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.50.720 2878 3128 1.7E-47 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.50.720 1159 1421 2.3E-57 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF55048 3902 3964 1.1E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF51735 1165 1382 2.98E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1477 1492 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:1.10.1200.10 1442 1539 8.1E-19 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3414 3430 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3509 3625 5.2E-46 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1799 1916 4.1E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 408 8.3E-46 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF55048 2189 2251 1.83E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.47.10 1540 1803 6.3E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.47.10 3243 3513 6.9E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:3.40.47.10 26 296 1.5E-90 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 Gene3D G3DSA:1.10.1200.10 3129 3237 1.7E-18 T 28-03-2018 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF51735 2879 3079 2.52E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF52151 3957 4069 1.6E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02295 0ebb42f5bca7e17d713f3a0c1b0f1f40 4153 SUPERFAMILY SSF52151 3780 3897 1.6E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS27820 f9a3e9eb3a7ddc06260bd330d5066f50 373 Pfam PF07687 Peptidase dimerisation domain 184 282 3.5E-15 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS27820 f9a3e9eb3a7ddc06260bd330d5066f50 373 SUPERFAMILY SSF55031 184 284 7.78E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS27820 f9a3e9eb3a7ddc06260bd330d5066f50 373 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 24 372 4.4E-155 T 28-03-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 SMD44_RS27820 f9a3e9eb3a7ddc06260bd330d5066f50 373 Gene3D G3DSA:3.30.70.360 188 293 2.6E-22 T 28-03-2018 SMD44_RS27820 f9a3e9eb3a7ddc06260bd330d5066f50 373 Gene3D G3DSA:3.40.630.10 23 187 5.6E-27 T 28-03-2018 SMD44_RS27820 f9a3e9eb3a7ddc06260bd330d5066f50 373 SUPERFAMILY SSF53187 293 372 4.37E-41 T 28-03-2018 SMD44_RS27820 f9a3e9eb3a7ddc06260bd330d5066f50 373 SUPERFAMILY SSF53187 30 196 4.37E-41 T 28-03-2018 SMD44_RS27820 f9a3e9eb3a7ddc06260bd330d5066f50 373 Pfam PF01546 Peptidase family M20/M25/M40 83 366 1.0E-20 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 Gene3D G3DSA:3.30.860.10 1 92 3.8E-40 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 Pfam PF00203 Ribosomal protein S19 3 83 1.2E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 SUPERFAMILY SSF54570 3 84 4.97E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.035 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 PIRSF PIRSF002144 1 93 3.1E-31 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.3E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.3E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.3E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25520 9487712655c4211a30ef48702ba57a40 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 1.4E-46 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD44_RS11355 be611c98dfa72159c6168f33f8f9e05e 407 Gene3D G3DSA:3.20.20.70 270 400 0.044 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS11355 be611c98dfa72159c6168f33f8f9e05e 407 Pfam PF02595 Glycerate kinase family 7 376 7.1E-131 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD44_RS11355 be611c98dfa72159c6168f33f8f9e05e 407 SUPERFAMILY SSF110738 5 378 4.71E-118 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD44_RS11355 be611c98dfa72159c6168f33f8f9e05e 407 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 6 377 2.0E-140 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD44_RS11355 be611c98dfa72159c6168f33f8f9e05e 407 PIRSF PIRSF006078 4 380 4.9E-107 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD44_RS11355 be611c98dfa72159c6168f33f8f9e05e 407 Gene3D G3DSA:3.90.1510.10 45 269 2.8E-82 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 SMD44_RS01680 d8ca2e8547710559ae05119d5acaa735 180 Gene3D G3DSA:1.10.260.40 2 75 2.5E-11 T 28-03-2018 SMD44_RS01680 d8ca2e8547710559ae05119d5acaa735 180 Pfam PF13560 Helix-turn-helix domain 9 70 2.0E-13 T 28-03-2018 SMD44_RS01680 d8ca2e8547710559ae05119d5acaa735 180 SMART SM00530 12 68 1.7E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS01680 d8ca2e8547710559ae05119d5acaa735 180 SUPERFAMILY SSF47413 5 70 1.63E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS11435 e4ea38dc88a72c45988a00bc5d257e85 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 14 115 1.1E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SMD44_RS11435 e4ea38dc88a72c45988a00bc5d257e85 118 SUPERFAMILY SSF89360 14 108 2.94E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SMD44_RS11435 e4ea38dc88a72c45988a00bc5d257e85 118 Gene3D G3DSA:2.60.300.12 14 118 8.9E-33 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SMD44_RS11435 e4ea38dc88a72c45988a00bc5d257e85 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 100 117 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 SMD44_RS11435 e4ea38dc88a72c45988a00bc5d257e85 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 6.1E-36 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 SMD44_RS23305 060f748bcfcfa60f1dabe525c2c05e0b 141 Pfam PF13581 Histidine kinase-like ATPase domain 8 137 1.5E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23305 060f748bcfcfa60f1dabe525c2c05e0b 141 Gene3D G3DSA:3.30.565.10 1 141 5.8E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19145 db845cc467b4eafe72916474f95f0ee7 315 SUPERFAMILY SSF52540 14 234 1.41E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19145 db845cc467b4eafe72916474f95f0ee7 315 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS19145 db845cc467b4eafe72916474f95f0ee7 315 Gene3D G3DSA:3.40.50.300 12 270 6.0E-65 T 28-03-2018 SMD44_RS19145 db845cc467b4eafe72916474f95f0ee7 315 SMART SM00382 38 220 1.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19145 db845cc467b4eafe72916474f95f0ee7 315 Pfam PF00005 ABC transporter 29 172 3.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19145 db845cc467b4eafe72916474f95f0ee7 315 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 21 314 1.7E-96 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD44_RS41525 230ca371658f8e5cd5478f8ffe946a71 83 SUPERFAMILY SSF53613 10 73 8.56E-10 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS41525 230ca371658f8e5cd5478f8ffe946a71 83 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 48 72 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD44_RS41525 230ca371658f8e5cd5478f8ffe946a71 83 Pfam PF00294 pfkB family carbohydrate kinase 10 72 8.1E-9 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS41525 230ca371658f8e5cd5478f8ffe946a71 83 Gene3D G3DSA:3.40.1190.20 2 82 7.6E-11 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 SUPERFAMILY SSF51905 4 303 2.59E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 Gene3D G3DSA:3.50.50.60 244 320 1.1E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 Gene3D G3DSA:3.50.50.60 94 241 9.2E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 2.3E-20 T 28-03-2018 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 2.3E-20 T 28-03-2018 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.3E-20 T 28-03-2018 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 2.3E-20 T 28-03-2018 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 2.3E-20 T 28-03-2018 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 Gene3D G3DSA:3.50.50.60 2 93 4.9E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13415 22dec48335c5e302218f7c5897028064 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 288 1.2E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 Gene3D G3DSA:1.10.630.10 2 408 3.7E-61 T 28-03-2018 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 SUPERFAMILY SSF48264 8 409 6.29E-82 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 99 110 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 349 358 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 358 369 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 145 161 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 325 340 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 297 324 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 197 219 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 162 177 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 PRINTS PR00359 B-class P450 signature 279 290 8.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31810 50f9a3ac5d52350db70a4645fa44f878 409 Pfam PF00067 Cytochrome P450 276 376 2.7E-13 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS01190 fcb1bcd948050e392fdf235ffc6eb297 260 SUPERFAMILY SSF54637 126 259 1.01E-7 T 28-03-2018 IPR029069 HotDog domain SMD44_RS01190 fcb1bcd948050e392fdf235ffc6eb297 260 Gene3D G3DSA:3.10.129.10 19 112 0.042 T 28-03-2018 SMD44_RS01190 fcb1bcd948050e392fdf235ffc6eb297 260 Pfam PF13622 Thioesterase-like superfamily 24 257 5.9E-29 T 28-03-2018 SMD44_RS26365 e88ef7f7160330c75bb17ad156868af0 239 Pfam PF13545 Crp-like helix-turn-helix domain 159 228 1.5E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD44_RS26365 e88ef7f7160330c75bb17ad156868af0 239 Pfam PF00027 Cyclic nucleotide-binding domain 40 126 1.8E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS26365 e88ef7f7160330c75bb17ad156868af0 239 Gene3D G3DSA:2.60.120.10 14 155 6.2E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS26365 e88ef7f7160330c75bb17ad156868af0 239 SMART SM00419 174 223 3.3E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD44_RS26365 e88ef7f7160330c75bb17ad156868af0 239 Gene3D G3DSA:1.10.10.10 156 237 4.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26365 e88ef7f7160330c75bb17ad156868af0 239 SMART SM00100 21 142 8.3E-7 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS26365 e88ef7f7160330c75bb17ad156868af0 239 SUPERFAMILY SSF51206 16 150 1.44E-22 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SMD44_RS26365 e88ef7f7160330c75bb17ad156868af0 239 SUPERFAMILY SSF46785 157 230 8.49E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 Gene3D G3DSA:1.10.287.130 190 256 3.8E-11 T 28-03-2018 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 Pfam PF00672 HAMP domain 147 195 3.8E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 302 408 5.3E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 259 3.8E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 9.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 364 9.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 350 9.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 SUPERFAMILY SSF158472 147 197 1.7E-6 T 28-03-2018 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 SUPERFAMILY SSF55874 250 411 9.69E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 Gene3D G3DSA:3.30.565.10 262 411 6.3E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 SMART SM00304 146 199 1.7E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 SUPERFAMILY SSF47384 183 260 5.49E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 SMART SM00388 200 260 7.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS01230 41f757cf61bd4cd3042366adecc73b5c 415 SMART SM00387 301 410 1.7E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:1.25.40.10 1061 1235 1.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Pfam PF00931 NB-ARC domain 344 599 1.2E-8 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SUPERFAMILY SSF48452 109 269 9.48E-35 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SUPERFAMILY SSF52540 307 595 2.21E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SUPERFAMILY SSF48452 1136 1229 5.06E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Pfam PF13424 Tetratricopeptide repeat 906 972 1.2E-10 T 28-03-2018 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM01043 114 261 3.0E-51 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:1.10.10.10 572 650 0.0012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:1.10.150.200 955 984 4.0E-6 T 28-03-2018 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:1.25.40.10 985 1060 2.0E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Pfam PF03704 Bacterial transcriptional activator domain 114 261 4.6E-45 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SUPERFAMILY SSF48452 885 1098 2.47E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM00028 1157 1190 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM00028 901 934 21.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM00028 941 974 0.088 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM00028 820 853 32.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM00028 780 813 31.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM00028 981 1014 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM00028 1021 1054 22.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SUPERFAMILY SSF46894 14 107 6.8E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SUPERFAMILY SSF48452 779 891 2.58E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:1.10.10.10 4 110 2.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:1.25.40.10 861 954 1.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 PRINTS PR00364 Disease resistance protein signature 346 361 7.8E-9 T 28-03-2018 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 PRINTS PR00364 Disease resistance protein signature 527 541 7.8E-9 T 28-03-2018 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 PRINTS PR00364 Disease resistance protein signature 427 441 7.8E-9 T 28-03-2018 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 SMART SM00862 27 107 1.8E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:1.25.40.10 111 276 1.6E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Pfam PF13374 Tetratricopeptide repeat 1158 1190 0.0055 T 28-03-2018 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 107 4.2E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:3.40.50.300 303 465 2.7E-12 T 28-03-2018 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:3.30.70.100 758 821 8.2E-8 T 28-03-2018 SMD44_RS13610 6b7116ba0799c3b31b0c54ba76a5030c 1254 Gene3D G3DSA:3.30.70.100 822 860 2.7E-6 T 28-03-2018 SMD44_RS24425 10ae1d1764a5927624ce4bf8a265591b 387 PIRSF PIRSF004762 1 380 3.5E-102 T 28-03-2018 SMD44_RS24425 10ae1d1764a5927624ce4bf8a265591b 387 Pfam PF04055 Radical SAM superfamily 61 229 4.8E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS24425 10ae1d1764a5927624ce4bf8a265591b 387 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 52 368 1.8E-91 T 28-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD44_RS24425 10ae1d1764a5927624ce4bf8a265591b 387 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 7 371 48.525 T 28-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD44_RS24425 10ae1d1764a5927624ce4bf8a265591b 387 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 10 367 3.4E-164 T 28-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD44_RS24425 10ae1d1764a5927624ce4bf8a265591b 387 SUPERFAMILY SSF102114 16 361 1.7E-43 T 28-03-2018 SMD44_RS24425 10ae1d1764a5927624ce4bf8a265591b 387 Gene3D G3DSA:3.20.20.70 3 370 1.2E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS20165 7fdb4147d53be8b15aa8d74306ae844b 181 SUPERFAMILY SSF55729 15 161 3.49E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS20165 7fdb4147d53be8b15aa8d74306ae844b 181 Gene3D G3DSA:3.40.630.30 8 158 1.3E-23 T 28-03-2018 SMD44_RS20165 7fdb4147d53be8b15aa8d74306ae844b 181 Pfam PF00583 Acetyltransferase (GNAT) family 55 154 2.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS23990 5f644c64f733040b5451483754b25a9a 310 SUPERFAMILY SSF53067 129 306 3.89E-38 T 28-03-2018 SMD44_RS23990 5f644c64f733040b5451483754b25a9a 310 Pfam PF02541 Ppx/GppA phosphatase family 26 305 1.4E-68 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SMD44_RS23990 5f644c64f733040b5451483754b25a9a 310 SUPERFAMILY SSF53067 2 125 9.5E-29 T 28-03-2018 SMD44_RS23990 5f644c64f733040b5451483754b25a9a 310 Gene3D G3DSA:3.30.420.40 1 124 1.7E-35 T 28-03-2018 SMD44_RS23990 5f644c64f733040b5451483754b25a9a 310 Gene3D G3DSA:3.30.420.150 127 308 1.4E-43 T 28-03-2018 SMD44_RS12945 729a51a1e5e4a172e82130f1a1962949 320 SUPERFAMILY SSF102114 7 259 3.27E-34 T 28-03-2018 SMD44_RS12945 729a51a1e5e4a172e82130f1a1962949 320 Pfam PF13186 Iron-sulfur cluster-binding domain 202 266 1.3E-5 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain SMD44_RS12945 729a51a1e5e4a172e82130f1a1962949 320 Pfam PF13353 4Fe-4S single cluster domain 16 103 4.5E-5 T 28-03-2018 SMD44_RS12945 729a51a1e5e4a172e82130f1a1962949 320 Pfam PF04055 Radical SAM superfamily 16 147 3.3E-11 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS12945 729a51a1e5e4a172e82130f1a1962949 320 Gene3D G3DSA:3.20.20.70 6 193 1.4E-19 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS29510 4c6dc30608ce884bf5cc7682d8d7429c 617 SMART SM00382 398 584 2.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29510 4c6dc30608ce884bf5cc7682d8d7429c 617 Pfam PF00664 ABC transporter transmembrane region 47 314 2.6E-30 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS29510 4c6dc30608ce884bf5cc7682d8d7429c 617 Gene3D G3DSA:1.20.1560.10 13 353 7.3E-55 T 28-03-2018 SMD44_RS29510 4c6dc30608ce884bf5cc7682d8d7429c 617 ProSitePatterns PS00211 ABC transporters family signature. 510 524 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS29510 4c6dc30608ce884bf5cc7682d8d7429c 617 SUPERFAMILY SSF90123 35 355 1.29E-63 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS29510 4c6dc30608ce884bf5cc7682d8d7429c 617 SUPERFAMILY SSF52540 368 607 2.56E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29510 4c6dc30608ce884bf5cc7682d8d7429c 617 Gene3D G3DSA:3.40.50.300 370 612 7.0E-67 T 28-03-2018 SMD44_RS29510 4c6dc30608ce884bf5cc7682d8d7429c 617 Pfam PF00005 ABC transporter 392 538 2.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS13930 71c843762cbedc9aad97f2b5904b8015 213 SMART SM00855 7 161 4.0E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS13930 71c843762cbedc9aad97f2b5904b8015 213 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMD44_RS13930 71c843762cbedc9aad97f2b5904b8015 213 Gene3D G3DSA:3.40.50.1240 6 206 2.5E-51 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS13930 71c843762cbedc9aad97f2b5904b8015 213 PIRSF PIRSF000709 3 172 3.2E-9 T 28-03-2018 SMD44_RS13930 71c843762cbedc9aad97f2b5904b8015 213 SUPERFAMILY SSF53254 7 204 4.17E-55 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS13930 71c843762cbedc9aad97f2b5904b8015 213 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 200 8.8E-55 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS39115 af12aecc7af7f49198d2c9b5aa39e3bb 170 SUPERFAMILY SSF52402 9 149 3.68E-18 T 28-03-2018 SMD44_RS39115 af12aecc7af7f49198d2c9b5aa39e3bb 170 Pfam PF00582 Universal stress protein family 10 146 2.5E-13 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS39115 af12aecc7af7f49198d2c9b5aa39e3bb 170 Gene3D G3DSA:3.40.50.620 8 150 2.6E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS35030 927514ce3cb2836445c8a5bb68017e41 327 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 12 185 2.0E-42 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS35030 927514ce3cb2836445c8a5bb68017e41 327 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 265 6.5E-14 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS35030 927514ce3cb2836445c8a5bb68017e41 327 SUPERFAMILY SSF51735 9 187 5.07E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35030 927514ce3cb2836445c8a5bb68017e41 327 Hamap MF_02129 L-carnitine dehydrogenase [lcdH]. 10 321 52.134 T 28-03-2018 IPR026578 L-carnitine dehydrogenase KEGG: 00040+1.1.1.10|MetaCyc: PWY-3602|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7472 SMD44_RS35030 927514ce3cb2836445c8a5bb68017e41 327 Gene3D G3DSA:3.40.50.720 1 191 1.7E-43 T 28-03-2018 SMD44_RS35030 927514ce3cb2836445c8a5bb68017e41 327 SUPERFAMILY SSF48179 190 275 1.19E-12 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS35030 927514ce3cb2836445c8a5bb68017e41 327 Gene3D G3DSA:1.10.1040.10 192 302 2.5E-16 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS30645 89aee52b744a5d66dadbf64fbd0e0c94 479 Pfam PF00171 Aldehyde dehydrogenase family 19 473 1.2E-160 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS30645 89aee52b744a5d66dadbf64fbd0e0c94 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS30645 89aee52b744a5d66dadbf64fbd0e0c94 479 SUPERFAMILY SSF53720 5 476 3.14E-157 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS30645 89aee52b744a5d66dadbf64fbd0e0c94 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS30645 89aee52b744a5d66dadbf64fbd0e0c94 479 Gene3D G3DSA:3.40.309.10 269 459 2.3E-67 T 28-03-2018 SMD44_RS30645 89aee52b744a5d66dadbf64fbd0e0c94 479 Gene3D G3DSA:3.40.605.10 2 268 8.1E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS40935 9cfd4c24e99ced636345505cfbff5124 351 Gene3D G3DSA:1.10.600.10 8 350 2.8E-80 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS40935 9cfd4c24e99ced636345505cfbff5124 351 Pfam PF00348 Polyprenyl synthetase 47 294 9.4E-42 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMD44_RS40935 9cfd4c24e99ced636345505cfbff5124 351 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 229 241 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMD44_RS40935 9cfd4c24e99ced636345505cfbff5124 351 SUPERFAMILY SSF48576 18 346 4.5E-65 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS14900 c72bcc63368336e78befc8c1eb68a020 340 PIRSF PIRSF036979 17 318 3.1E-109 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SMD44_RS14900 c72bcc63368336e78befc8c1eb68a020 340 ProSitePatterns PS01053 Arginase family signature. 242 263 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 SMD44_RS14900 c72bcc63368336e78befc8c1eb68a020 340 TIGRFAM TIGR01230 agmatinase: agmatinase 39 311 1.3E-70 T 28-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 SMD44_RS14900 c72bcc63368336e78befc8c1eb68a020 340 Pfam PF00491 Arginase family 40 310 1.9E-91 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SMD44_RS14900 c72bcc63368336e78befc8c1eb68a020 340 Gene3D G3DSA:3.40.800.10 4 322 9.8E-106 T 28-03-2018 SMD44_RS14900 c72bcc63368336e78befc8c1eb68a020 340 SUPERFAMILY SSF52768 19 314 3.6E-99 T 28-03-2018 SMD44_RS14900 c72bcc63368336e78befc8c1eb68a020 340 PRINTS PR00116 Arginase signature 239 268 1.8E-14 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SMD44_RS14900 c72bcc63368336e78befc8c1eb68a020 340 PRINTS PR00116 Arginase signature 126 141 1.8E-14 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 SMD44_RS04640 84c1ba13c2ff31fe0f54fa9de9446d05 451 Pfam PF03796 DnaB-like helicase C terminal domain 190 446 9.5E-91 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 SMD44_RS04640 84c1ba13c2ff31fe0f54fa9de9446d05 451 SUPERFAMILY SSF48024 13 123 2.22E-27 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SMD44_RS04640 84c1ba13c2ff31fe0f54fa9de9446d05 451 Pfam PF00772 DnaB-like helicase N terminal domain 15 116 3.7E-24 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SMD44_RS04640 84c1ba13c2ff31fe0f54fa9de9446d05 451 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 15 449 1.4E-126 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 SMD44_RS04640 84c1ba13c2ff31fe0f54fa9de9446d05 451 Gene3D G3DSA:3.40.50.300 173 451 3.9E-54 T 28-03-2018 SMD44_RS04640 84c1ba13c2ff31fe0f54fa9de9446d05 451 Gene3D G3DSA:1.10.860.10 7 156 9.4E-36 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SMD44_RS04640 84c1ba13c2ff31fe0f54fa9de9446d05 451 SUPERFAMILY SSF52540 190 440 1.81E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11145 cd683e9bb94ffdb43f034d11734a8c63 223 SUPERFAMILY SSF51391 14 218 1.44E-58 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD44_RS11145 cd683e9bb94ffdb43f034d11734a8c63 223 Pfam PF02581 Thiamine monophosphate synthase 19 203 5.6E-50 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD44_RS11145 cd683e9bb94ffdb43f034d11734a8c63 223 Gene3D G3DSA:3.20.20.70 8 221 5.6E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS11145 cd683e9bb94ffdb43f034d11734a8c63 223 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 19 214 9.6E-58 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD44_RS11145 cd683e9bb94ffdb43f034d11734a8c63 223 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 16 221 24.087 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD44_RS00695 274301ebde7cc477d5f3e61a4d1f45dd 220 Pfam PF13578 Methyltransferase domain 81 184 1.9E-18 T 28-03-2018 SMD44_RS00695 274301ebde7cc477d5f3e61a4d1f45dd 220 SUPERFAMILY SSF53335 55 218 5.79E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS00695 274301ebde7cc477d5f3e61a4d1f45dd 220 Gene3D G3DSA:3.40.50.150 45 212 1.3E-29 T 28-03-2018 SMD44_RS26715 96764fefa652841f35e76b8001ca3fe3 192 Pfam PF14081 Domain of unknown function (DUF4262) 57 176 2.0E-27 T 28-03-2018 IPR025358 Protein of unknown function DUF4262 SMD44_RS40700 e953c6262da96ff2433ac8293f35a94b 383 Gene3D G3DSA:3.40.50.300 1 119 2.9E-5 T 28-03-2018 SMD44_RS40700 e953c6262da96ff2433ac8293f35a94b 383 SUPERFAMILY SSF52540 1 250 1.17E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21105 159014dc9e32604642079eeaa0bb2827 119 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 3.0E-24 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMD44_RS21105 159014dc9e32604642079eeaa0bb2827 119 SMART SM01234 1 68 2.5E-39 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMD44_RS21105 159014dc9e32604642079eeaa0bb2827 119 Pfam PF01809 Haemolytic domain 5 68 3.7E-26 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMD44_RS21105 159014dc9e32604642079eeaa0bb2827 119 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 5.0E-25 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMD44_RS21105 159014dc9e32604642079eeaa0bb2827 119 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.466 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMD44_RS20210 80cedf0505185cdf07c068684fe33942 153 Gene3D G3DSA:3.40.140.10 1 149 2.1E-48 T 28-03-2018 SMD44_RS20210 80cedf0505185cdf07c068684fe33942 153 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 144 48.137 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SMD44_RS20210 80cedf0505185cdf07c068684fe33942 153 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 48 85 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMD44_RS20210 80cedf0505185cdf07c068684fe33942 153 SUPERFAMILY SSF53927 1 144 1.67E-52 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMD44_RS20210 80cedf0505185cdf07c068684fe33942 153 Pfam PF14437 MafB19-like deaminase 1 142 1.1E-29 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 SUPERFAMILY SSF53901 409 429 1.23E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 SUPERFAMILY SSF53901 154 378 1.23E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 SUPERFAMILY SSF53901 14 127 1.23E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 SUPERFAMILY SSF55048 681 744 5.75E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 Gene3D G3DSA:3.40.366.10 549 735 2.7E-50 T 28-03-2018 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 Pfam PF00698 Acyl transferase domain 556 873 2.9E-80 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 385 520 9.2E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 Gene3D G3DSA:3.40.366.10 736 859 9.2E-21 T 28-03-2018 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 Gene3D G3DSA:3.40.47.10 273 432 1.3E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 266 382 1.7E-37 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 15 258 1.6E-79 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 558 854 2.7E-88 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 SMART SM00825 Beta-ketoacyl synthase 17 434 2.6E-181 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 SUPERFAMILY SSF52151 554 683 1.12E-59 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 SUPERFAMILY SSF52151 747 842 1.12E-59 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS32005 d0c06006f931cd6657eac726b644f12a 920 Gene3D G3DSA:3.40.47.10 8 269 3.4E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS33050 14d444c71edf10d0bd1b9afa2f429e2d 344 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 198 226 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS33050 14d444c71edf10d0bd1b9afa2f429e2d 344 SUPERFAMILY SSF51735 48 291 4.1E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS33050 14d444c71edf10d0bd1b9afa2f429e2d 344 Pfam PF00106 short chain dehydrogenase 53 254 8.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33050 14d444c71edf10d0bd1b9afa2f429e2d 344 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 51 205 0.0032 T 28-03-2018 SMD44_RS33050 14d444c71edf10d0bd1b9afa2f429e2d 344 Gene3D G3DSA:3.40.50.720 35 340 4.1E-58 T 28-03-2018 SMD44_RS33050 14d444c71edf10d0bd1b9afa2f429e2d 344 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 139 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33050 14d444c71edf10d0bd1b9afa2f429e2d 344 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 52 69 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33050 14d444c71edf10d0bd1b9afa2f429e2d 344 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 189 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS18330 c64ae2faf07c7657b4ee555e14293d80 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 372 23.692 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SMD44_RS18330 c64ae2faf07c7657b4ee555e14293d80 372 Pfam PF00266 Aminotransferase class-V 18 331 1.6E-21 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS18330 c64ae2faf07c7657b4ee555e14293d80 372 Gene3D G3DSA:3.40.640.10 21 260 6.7E-28 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS18330 c64ae2faf07c7657b4ee555e14293d80 372 PIRSF PIRSF000525 1 372 2.0E-75 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SMD44_RS18330 c64ae2faf07c7657b4ee555e14293d80 372 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 11 372 9.2E-215 T 28-03-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 SMD44_RS18330 c64ae2faf07c7657b4ee555e14293d80 372 Gene3D G3DSA:3.90.1150.10 261 372 3.1E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS18330 c64ae2faf07c7657b4ee555e14293d80 372 SUPERFAMILY SSF53383 12 371 1.58E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS06165 b7a1b2801ed5b8ac2593914916a11458 138 SUPERFAMILY SSF51735 17 135 1.7E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS06165 b7a1b2801ed5b8ac2593914916a11458 138 SMART SM00881 12 105 2.9E-18 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS06165 b7a1b2801ed5b8ac2593914916a11458 138 Pfam PF13380 CoA binding domain 18 131 8.1E-37 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS06165 b7a1b2801ed5b8ac2593914916a11458 138 Gene3D G3DSA:3.40.50.720 16 134 4.3E-30 T 28-03-2018 SMD44_RS05575 fb9c8604b245048b6e7a2d7ec71d6463 382 Gene3D G3DSA:3.60.20.30 242 381 2.7E-42 T 28-03-2018 SMD44_RS05575 fb9c8604b245048b6e7a2d7ec71d6463 382 SUPERFAMILY SSF56235 239 373 1.75E-84 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS05575 fb9c8604b245048b6e7a2d7ec71d6463 382 SUPERFAMILY SSF56235 58 210 1.75E-84 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS05575 fb9c8604b245048b6e7a2d7ec71d6463 382 Pfam PF01112 Asparaginase 59 368 4.8E-101 T 28-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 Pfam PF01434 Peptidase family M41 432 631 9.9E-70 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 13 643 34.041 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 SUPERFAMILY SSF140990 451 633 1.96E-59 T 28-03-2018 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 Gene3D G3DSA:3.40.50.300 180 377 2.8E-59 T 28-03-2018 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 237 369 1.8E-42 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 Pfam PF06480 FtsH Extracellular 42 137 4.6E-9 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 SUPERFAMILY SSF52540 197 442 4.86E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 Gene3D G3DSA:1.10.8.60 378 443 4.3E-23 T 28-03-2018 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 146 631 5.3E-189 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 SMART SM00382 233 373 2.9E-23 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS30450 c05d2e25be2632ae1df7196ddb4cbff7 643 ProSitePatterns PS00674 AAA-protein family signature. 341 359 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMD44_RS27585 67ddfd8fd616ad31aad3e10b22c35141 893 Gene3D G3DSA:1.25.40.120 328 887 0.0044 T 28-03-2018 SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 SUPERFAMILY SSF52518 14 179 2.8E-46 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 173 5.0E-50 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 Gene3D G3DSA:3.40.50.1220 197 351 1.6E-41 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 Gene3D G3DSA:3.40.50.970 352 557 2.1E-41 T 28-03-2018 SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 Gene3D G3DSA:3.40.50.970 6 196 8.3E-49 T 28-03-2018 SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 334 3.7E-36 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 540 1.1E-40 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 SUPERFAMILY SSF52467 194 378 1.42E-43 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS22810 d57fadc02ae7d79bb919be871e77872b 561 SUPERFAMILY SSF52518 370 556 1.81E-57 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS26930 eaa852e95fe92e35475441f9efaf91b5 274 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 89 130 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 SMD44_RS26930 eaa852e95fe92e35475441f9efaf91b5 274 PIRSF PIRSF000477 9 274 5.3E-88 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SMD44_RS26930 eaa852e95fe92e35475441f9efaf91b5 274 Pfam PF01048 Phosphorylase superfamily 36 271 1.5E-42 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS26930 eaa852e95fe92e35475441f9efaf91b5 274 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 35 270 3.9E-104 T 28-03-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SMD44_RS26930 eaa852e95fe92e35475441f9efaf91b5 274 Gene3D G3DSA:3.40.50.1580 7 274 1.1E-62 T 28-03-2018 SMD44_RS26930 eaa852e95fe92e35475441f9efaf91b5 274 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 35 270 2.9E-76 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SMD44_RS26930 eaa852e95fe92e35475441f9efaf91b5 274 SUPERFAMILY SSF53167 17 273 5.7E-80 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS15540 79e00c949132d8060eb78a445455d811 443 SUPERFAMILY SSF103473 1 431 8.24E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS15540 79e00c949132d8060eb78a445455d811 443 Gene3D G3DSA:1.20.1250.20 11 217 6.8E-22 T 28-03-2018 SMD44_RS15540 79e00c949132d8060eb78a445455d811 443 Gene3D G3DSA:1.20.1250.20 236 434 6.1E-17 T 28-03-2018 SMD44_RS15540 79e00c949132d8060eb78a445455d811 443 Pfam PF07690 Major Facilitator Superfamily 38 324 6.7E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS40255 24402469c081af85d3e2c7ab67f06382 174 SUPERFAMILY SSF47413 44 113 6.82E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS40255 24402469c081af85d3e2c7ab67f06382 174 SMART SM00530 54 109 7.0E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS40255 24402469c081af85d3e2c7ab67f06382 174 Gene3D G3DSA:1.10.260.40 43 117 1.7E-14 T 28-03-2018 SMD44_RS40255 24402469c081af85d3e2c7ab67f06382 174 Pfam PF13560 Helix-turn-helix domain 52 111 5.9E-11 T 28-03-2018 SMD44_RS04530 294607d0e59a5c648e3d3851df7495c4 278 Pfam PF02945 Recombination endonuclease VII 67 145 2.2E-23 T 28-03-2018 IPR004211 Recombination endonuclease VII SMD44_RS04530 294607d0e59a5c648e3d3851df7495c4 278 Gene3D G3DSA:3.40.1800.10 69 142 1.0E-7 T 28-03-2018 SMD44_RS04530 294607d0e59a5c648e3d3851df7495c4 278 SUPERFAMILY SSF54060 72 148 9.06E-18 T 28-03-2018 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 6.7E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 6.7E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 6.7E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 6.7E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 6.7E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 6.7E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 Gene3D G3DSA:3.40.50.720 1 182 3.6E-48 T 28-03-2018 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 320 3.1E-48 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 Gene3D G3DSA:1.10.1040.10 183 333 8.6E-50 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 SUPERFAMILY SSF51735 5 183 7.18E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 SUPERFAMILY SSF48179 182 334 2.95E-54 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 325 37.496 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 PIRSF PIRSF000114 2 335 5.7E-98 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS30280 956eafe4e753367ef4305ddf3ebe11c7 336 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7 163 5.0E-51 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS38240 b5c0462d2105b55d9fe69958134432e8 344 Gene3D G3DSA:3.40.50.2300 170 333 8.4E-47 T 28-03-2018 SMD44_RS38240 b5c0462d2105b55d9fe69958134432e8 344 Gene3D G3DSA:3.40.50.2300 55 169 7.7E-23 T 28-03-2018 SMD44_RS38240 b5c0462d2105b55d9fe69958134432e8 344 Pfam PF13377 Periplasmic binding protein-like domain 172 330 2.4E-37 T 28-03-2018 SMD44_RS38240 b5c0462d2105b55d9fe69958134432e8 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 47 9.4E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS38240 b5c0462d2105b55d9fe69958134432e8 344 SUPERFAMILY SSF53822 59 332 8.83E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS38240 b5c0462d2105b55d9fe69958134432e8 344 SUPERFAMILY SSF47413 4 51 6.44E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS38240 b5c0462d2105b55d9fe69958134432e8 344 Gene3D G3DSA:1.10.260.40 1 54 2.0E-16 T 28-03-2018 SMD44_RS38240 b5c0462d2105b55d9fe69958134432e8 344 SMART SM00354 2 69 6.1E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 403 39.734 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 355 366 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 322 347 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 5.2E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 Gene3D G3DSA:3.40.50.1260 1 183 1.0E-62 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 SUPERFAMILY SSF53748 4 402 2.83E-138 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 Pfam PF00162 Phosphoglycerate kinase 12 393 8.2E-143 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 PIRSF PIRSF000724 1 403 4.0E-129 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10120 229500ef589bdd44b9c436e17f7c16f6 403 Gene3D G3DSA:3.40.50.1260 184 391 3.4E-79 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS16100 a78c7dda5d0d4afbdcbb93aec56202bc 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 288 2.4E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS16100 a78c7dda5d0d4afbdcbb93aec56202bc 304 Gene3D G3DSA:1.10.3720.10 25 292 4.7E-40 T 28-03-2018 SMD44_RS16100 a78c7dda5d0d4afbdcbb93aec56202bc 304 SUPERFAMILY SSF161098 37 304 5.51E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS22440 4bcc12dafb2aa28921857d4de74043ed 416 Pfam PF13560 Helix-turn-helix domain 16 75 5.7E-14 T 28-03-2018 SMD44_RS22440 4bcc12dafb2aa28921857d4de74043ed 416 SMART SM00530 19 75 1.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS22440 4bcc12dafb2aa28921857d4de74043ed 416 SUPERFAMILY SSF47413 10 72 2.82E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS22440 4bcc12dafb2aa28921857d4de74043ed 416 Gene3D G3DSA:1.10.260.40 15 87 8.2E-17 T 28-03-2018 SMD44_RS21850 fdfcc9c8d20e447a2bb8264b7dad886c 262 Pfam PF00795 Carbon-nitrogen hydrolase 17 250 1.4E-44 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS21850 fdfcc9c8d20e447a2bb8264b7dad886c 262 SUPERFAMILY SSF56317 1 259 2.62E-68 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS21850 fdfcc9c8d20e447a2bb8264b7dad886c 262 Gene3D G3DSA:3.60.110.10 1 262 5.9E-73 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS21850 fdfcc9c8d20e447a2bb8264b7dad886c 262 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 145 165 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site SMD44_RS10425 a5ea2a3118a1d11a4d71e7956e1e5169 167 Gene3D G3DSA:3.40.630.30 1 99 1.0E-16 T 28-03-2018 SMD44_RS10425 a5ea2a3118a1d11a4d71e7956e1e5169 167 Gene3D G3DSA:3.40.630.30 100 156 4.8E-12 T 28-03-2018 SMD44_RS10425 a5ea2a3118a1d11a4d71e7956e1e5169 167 SUPERFAMILY SSF55729 6 165 2.3E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS10425 a5ea2a3118a1d11a4d71e7956e1e5169 167 Pfam PF13508 Acetyltransferase (GNAT) domain 56 144 2.6E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 Gene3D G3DSA:3.30.470.20 186 381 2.3E-45 T 28-03-2018 SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 SUPERFAMILY SSF52440 6 99 1.58E-25 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 Gene3D G3DSA:3.30.1490.20 119 185 3.7E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 SUPERFAMILY SSF56059 104 306 4.77E-59 T 28-03-2018 SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 Pfam PF02222 ATP-grasp domain 113 286 2.0E-48 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 Gene3D G3DSA:3.40.50.20 5 90 3.1E-22 T 28-03-2018 SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 7 365 39.963 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 8 368 1.8E-114 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SMD44_RS16550 31ad29f648d48fe4db343a5698268c60 385 SUPERFAMILY SSF51246 312 380 7.69E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMD44_RS12125 15bdaf752dcc3e62652dfa1896bea328 294 SUPERFAMILY SSF54506 12 292 1.57E-59 T 28-03-2018 SMD44_RS12125 15bdaf752dcc3e62652dfa1896bea328 294 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 10 291 2.3E-53 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD44_RS12125 15bdaf752dcc3e62652dfa1896bea328 294 PIRSF PIRSF016184 10 294 2.7E-64 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD44_RS12125 15bdaf752dcc3e62652dfa1896bea328 294 Gene3D G3DSA:3.10.310.10 8 137 3.5E-31 T 28-03-2018 SMD44_RS12125 15bdaf752dcc3e62652dfa1896bea328 294 Gene3D G3DSA:3.10.310.10 138 286 3.6E-36 T 28-03-2018 SMD44_RS12125 15bdaf752dcc3e62652dfa1896bea328 294 Pfam PF02567 Phenazine biosynthesis-like protein 17 291 7.8E-69 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD44_RS39080 870dfcd7adb5a0ba8b3df2f0a045475f 152 Pfam PF02566 OsmC-like protein 54 149 1.2E-17 T 28-03-2018 IPR003718 OsmC/Ohr family SMD44_RS39080 870dfcd7adb5a0ba8b3df2f0a045475f 152 Gene3D G3DSA:3.30.300.20 21 152 1.1E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS39080 870dfcd7adb5a0ba8b3df2f0a045475f 152 SUPERFAMILY SSF82784 27 149 1.57E-30 T 28-03-2018 IPR003718 OsmC/Ohr family SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 SUPERFAMILY SSF52518 70 482 2.85E-123 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 SUPERFAMILY SSF52922 725 900 7.85E-53 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 Gene3D G3DSA:3.40.50.970 69 485 5.7E-77 T 28-03-2018 SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 150 307 4.0E-9 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 Gene3D G3DSA:3.40.50.970 487 727 3.2E-67 T 28-03-2018 SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 907 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 Gene3D G3DSA:3.40.50.920 729 909 4.8E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 SUPERFAMILY SSF52518 489 722 1.12E-84 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS12710 4b5b885991d5025a71a30a7cae3a6024 915 PIRSF PIRSF000156 10 910 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD44_RS42620 2e7f0c3de1f1cf6fd78496470c0abde6 607 SUPERFAMILY SSF56112 120 381 7.36E-64 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS42620 2e7f0c3de1f1cf6fd78496470c0abde6 607 Gene3D G3DSA:3.30.200.20 106 218 1.6E-19 T 28-03-2018 SMD44_RS42620 2e7f0c3de1f1cf6fd78496470c0abde6 607 Gene3D G3DSA:1.10.510.10 219 404 8.8E-44 T 28-03-2018 SMD44_RS42620 2e7f0c3de1f1cf6fd78496470c0abde6 607 Pfam PF00069 Protein kinase domain 128 376 5.1E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS42620 2e7f0c3de1f1cf6fd78496470c0abde6 607 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 134 157 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS42620 2e7f0c3de1f1cf6fd78496470c0abde6 607 SMART SM00220 128 382 3.7E-55 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS42620 2e7f0c3de1f1cf6fd78496470c0abde6 607 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 249 261 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS27130 1a8c30b4b36c9c40f4ee9028cfa05975 236 SMART SM00421 152 209 9.9E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27130 1a8c30b4b36c9c40f4ee9028cfa05975 236 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 9.1E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27130 1a8c30b4b36c9c40f4ee9028cfa05975 236 SUPERFAMILY SSF46894 145 215 2.14E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS27130 1a8c30b4b36c9c40f4ee9028cfa05975 236 Gene3D G3DSA:1.10.10.10 111 219 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27130 1a8c30b4b36c9c40f4ee9028cfa05975 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27130 1a8c30b4b36c9c40f4ee9028cfa05975 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27130 1a8c30b4b36c9c40f4ee9028cfa05975 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 110.115 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 Pfam PF13662 Toprim domain 79 170 1.7E-26 T 28-03-2018 IPR006171 TOPRIM domain SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 SUPERFAMILY SSF111304 3 197 5.36E-76 T 28-03-2018 IPR023627 Recombination protein RecR SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 Gene3D G3DSA:1.10.150.20 3 77 0.65 T 28-03-2018 SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 SMART SM00493 79 164 1.1E-18 T 28-03-2018 IPR006171 TOPRIM domain SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 Pfam PF02132 RecR protein 38 77 4.2E-17 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 1.4E-85 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 Gene3D G3DSA:3.40.1360.10 78 169 1.3E-40 T 28-03-2018 SMD44_RS22770 8338399d894976fc64692ca74c9e7bc0 199 Pfam PF00633 Helix-hairpin-helix motif 2 27 7.4E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 SUPERFAMILY SSF52540 390 650 1.96E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 SMART SM00382 421 625 3.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 Gene3D G3DSA:1.20.1560.10 13 383 1.6E-88 T 28-03-2018 SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 SUPERFAMILY SSF90123 110 383 6.28E-84 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 SUPERFAMILY SSF90123 25 69 6.28E-84 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 Pfam PF00005 ABC transporter 413 579 1.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 ProSitePatterns PS00211 ABC transporters family signature. 551 565 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 Pfam PF00664 ABC transporter transmembrane region 42 350 2.3E-56 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS13315 6dff9280fa81d9a0c1e64b911fdf5446 658 Gene3D G3DSA:3.40.50.300 384 655 2.1E-74 T 28-03-2018 SMD44_RS20765 0e0bdc370f5fc4cc06328cb7d36bd79e 291 SUPERFAMILY SSF55920 18 264 4.97E-27 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS20765 0e0bdc370f5fc4cc06328cb7d36bd79e 291 Pfam PF00557 Metallopeptidase family M24 23 263 1.6E-28 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS20765 0e0bdc370f5fc4cc06328cb7d36bd79e 291 Gene3D G3DSA:3.90.230.10 17 268 6.4E-32 T 28-03-2018 SMD44_RS03465 f2410d589407a66e84d6e0bef373fcfa 516 Gene3D G3DSA:3.40.50.980 168 320 1.4E-29 T 28-03-2018 SMD44_RS03465 f2410d589407a66e84d6e0bef373fcfa 516 Pfam PF00501 AMP-binding enzyme 8 411 4.6E-67 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS03465 f2410d589407a66e84d6e0bef373fcfa 516 SUPERFAMILY SSF56801 3 511 2.75E-118 T 28-03-2018 SMD44_RS03465 f2410d589407a66e84d6e0bef373fcfa 516 Gene3D G3DSA:3.40.50.980 1 167 1.5E-30 T 28-03-2018 SMD44_RS03465 f2410d589407a66e84d6e0bef373fcfa 516 Gene3D G3DSA:2.30.38.10 321 404 1.4E-13 T 28-03-2018 SMD44_RS03465 f2410d589407a66e84d6e0bef373fcfa 516 Gene3D G3DSA:3.30.300.30 406 516 6.6E-31 T 28-03-2018 SMD44_RS03465 f2410d589407a66e84d6e0bef373fcfa 516 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 498 1.0E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS19240 6f5bc2c4d9e511bab97535e6eed795c4 141 Gene3D G3DSA:3.50.80.10 1 141 6.5E-52 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain SMD44_RS19240 6f5bc2c4d9e511bab97535e6eed795c4 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 1.1E-50 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SMD44_RS19240 6f5bc2c4d9e511bab97535e6eed795c4 141 SUPERFAMILY SSF69500 1 140 2.35E-46 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain SMD44_RS19240 6f5bc2c4d9e511bab97535e6eed795c4 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 31.249 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SMD44_RS19240 6f5bc2c4d9e511bab97535e6eed795c4 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 140 9.0E-42 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SMD44_RS40105 b09dd6c369b7ea140e41c91759c37764 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 271 2.9E-43 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS40105 b09dd6c369b7ea140e41c91759c37764 272 Gene3D G3DSA:3.40.190.10 150 227 4.8E-10 T 28-03-2018 SMD44_RS40105 b09dd6c369b7ea140e41c91759c37764 272 SMART SM00062 48 272 1.1E-32 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS40105 b09dd6c369b7ea140e41c91759c37764 272 Gene3D G3DSA:3.40.190.10 38 149 3.6E-27 T 28-03-2018 SMD44_RS40105 b09dd6c369b7ea140e41c91759c37764 272 SUPERFAMILY SSF53850 1 271 2.33E-51 T 28-03-2018 SMD44_RS27300 e6fa0f0010d3763a6ce464e87c0fbcb4 420 SUPERFAMILY SSF52743 40 326 4.84E-70 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27300 e6fa0f0010d3763a6ce464e87c0fbcb4 420 Pfam PF00082 Subtilase family 57 313 4.2E-40 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27300 e6fa0f0010d3763a6ce464e87c0fbcb4 420 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 46 409 1.4E-95 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin SMD44_RS27300 e6fa0f0010d3763a6ce464e87c0fbcb4 420 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 62 73 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS27300 e6fa0f0010d3763a6ce464e87c0fbcb4 420 Gene3D G3DSA:3.40.50.200 25 326 9.1E-74 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27300 e6fa0f0010d3763a6ce464e87c0fbcb4 420 PRINTS PR00723 Subtilisin serine protease family (S8) signature 57 76 7.6E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS27300 e6fa0f0010d3763a6ce464e87c0fbcb4 420 PRINTS PR00723 Subtilisin serine protease family (S8) signature 98 111 7.6E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS27300 e6fa0f0010d3763a6ce464e87c0fbcb4 420 PRINTS PR00723 Subtilisin serine protease family (S8) signature 261 277 7.6E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS07675 ea15b289f82653d6f03ca46c2da0972e 275 Pfam PF03180 NLPA lipoprotein 33 272 2.2E-94 T 28-03-2018 IPR004872 Lipoprotein NlpA family SMD44_RS07675 ea15b289f82653d6f03ca46c2da0972e 275 Gene3D G3DSA:3.40.190.10 132 274 1.3E-54 T 28-03-2018 SMD44_RS07675 ea15b289f82653d6f03ca46c2da0972e 275 PIRSF PIRSF002854 1 273 2.6E-105 T 28-03-2018 IPR004872 Lipoprotein NlpA family SMD44_RS07675 ea15b289f82653d6f03ca46c2da0972e 275 Gene3D G3DSA:3.40.190.10 29 131 1.7E-21 T 28-03-2018 SMD44_RS07675 ea15b289f82653d6f03ca46c2da0972e 275 SUPERFAMILY SSF53850 32 273 1.21E-82 T 28-03-2018 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 SUPERFAMILY SSF46894 127 203 1.09E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 1.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 1.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 1.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 197 1.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 SMART SM00448 4 117 1.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 Gene3D G3DSA:1.10.10.10 128 203 3.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 SUPERFAMILY SSF52172 4 131 7.4E-32 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 Pfam PF00072 Response regulator receiver domain 6 117 2.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 Gene3D G3DSA:3.40.50.2300 3 127 2.0E-35 T 28-03-2018 SMD44_RS20020 0560535e53c45ece3d9e52b4e52ac8e3 203 SMART SM00421 140 197 1.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11330 b9a9085abd0f8f8b52b39f0bfb984eac 93 Gene3D G3DSA:3.30.70.920 1 83 4.0E-19 T 28-03-2018 SMD44_RS11330 b9a9085abd0f8f8b52b39f0bfb984eac 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 6.2E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS11330 b9a9085abd0f8f8b52b39f0bfb984eac 93 SUPERFAMILY SSF54909 2 78 2.15E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS29250 1f28fde0b4742405a9cd22300297de89 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 264 9.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS29250 1f28fde0b4742405a9cd22300297de89 268 SUPERFAMILY SSF161098 33 258 1.13E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS29250 1f28fde0b4742405a9cd22300297de89 268 Gene3D G3DSA:1.10.3720.10 1 267 4.1E-47 T 28-03-2018 SMD44_RS00525 41fede9704415562d2db28574f806367 670 SUPERFAMILY SSF117892 57 206 1.83E-12 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS00525 41fede9704415562d2db28574f806367 670 Pfam PF01145 SPFH domain / Band 7 family 32 182 4.3E-8 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS03090 a1ec52415f237628630afacb805ad6c2 506 Pfam PF07690 Major Facilitator Superfamily 33 422 1.9E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS03090 a1ec52415f237628630afacb805ad6c2 506 SUPERFAMILY SSF103473 261 480 2.09E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03090 a1ec52415f237628630afacb805ad6c2 506 SUPERFAMILY SSF103473 22 209 2.09E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03090 a1ec52415f237628630afacb805ad6c2 506 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 29 418 6.3E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS03090 a1ec52415f237628630afacb805ad6c2 506 Gene3D G3DSA:1.20.1250.20 17 214 1.5E-35 T 28-03-2018 SMD44_RS03090 a1ec52415f237628630afacb805ad6c2 506 Gene3D G3DSA:1.20.1250.20 265 486 7.9E-28 T 28-03-2018 SMD44_RS12475 94ed6b36c59f93a06e38b53515c01dc1 475 Pfam PF00083 Sugar (and other) transporter 47 259 2.6E-31 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD44_RS12475 94ed6b36c59f93a06e38b53515c01dc1 475 Gene3D G3DSA:1.20.1250.20 252 464 2.4E-25 T 28-03-2018 SMD44_RS12475 94ed6b36c59f93a06e38b53515c01dc1 475 ProSitePatterns PS00217 Sugar transport proteins signature 2. 154 179 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS12475 94ed6b36c59f93a06e38b53515c01dc1 475 Gene3D G3DSA:1.20.1250.20 38 251 8.3E-26 T 28-03-2018 SMD44_RS12475 94ed6b36c59f93a06e38b53515c01dc1 475 SUPERFAMILY SSF103473 42 454 2.09E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS09675 39f00721963842ee849f50d622c81510 332 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 298 332 4.3E-5 T 28-03-2018 SMD44_RS03395 39c1ec91a7445df91afd208a1c536e30 355 Gene3D G3DSA:3.40.47.10 217 343 3.1E-6 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS03395 39c1ec91a7445df91afd208a1c536e30 355 SUPERFAMILY SSF53901 8 124 3.33E-15 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS03395 39c1ec91a7445df91afd208a1c536e30 355 SUPERFAMILY SSF53901 182 335 3.33E-15 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS03395 39c1ec91a7445df91afd208a1c536e30 355 Gene3D G3DSA:3.40.47.10 8 216 1.8E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS03395 39c1ec91a7445df91afd208a1c536e30 355 PIRSF PIRSF000429 197 342 1.0E-11 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS03395 39c1ec91a7445df91afd208a1c536e30 355 PIRSF PIRSF000429 6 190 0.55 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS30695 f12770ed245202b06417db0d54d4ef5d 241 SUPERFAMILY SSF51695 6 221 5.86E-47 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS30695 f12770ed245202b06417db0d54d4ef5d 241 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 219 2.2E-31 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD44_RS30695 f12770ed245202b06417db0d54d4ef5d 241 Gene3D G3DSA:3.20.20.190 1 239 5.7E-50 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS38400 286ab344c02713a808ef394e8710eebd 554 SUPERFAMILY SSF53067 289 509 1.7E-23 T 28-03-2018 SMD44_RS38400 286ab344c02713a808ef394e8710eebd 554 Gene3D G3DSA:3.30.420.40 282 529 1.6E-31 T 28-03-2018 SMD44_RS38400 286ab344c02713a808ef394e8710eebd 554 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 43 284 5.0E-35 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD44_RS38400 286ab344c02713a808ef394e8710eebd 554 SUPERFAMILY SSF53067 44 287 9.07E-47 T 28-03-2018 SMD44_RS38400 286ab344c02713a808ef394e8710eebd 554 PIRSF PIRSF000538 41 521 9.3E-62 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD44_RS38400 286ab344c02713a808ef394e8710eebd 554 Gene3D G3DSA:3.30.420.40 40 281 6.7E-61 T 28-03-2018 SMD44_RS38400 286ab344c02713a808ef394e8710eebd 554 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 349 470 2.4E-13 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD44_RS32920 ba403da06411d650b76d2d97280b5735 267 Pfam PF01048 Phosphorylase superfamily 72 166 1.6E-7 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS32920 ba403da06411d650b76d2d97280b5735 267 Gene3D G3DSA:3.40.50.1580 37 252 2.4E-18 T 28-03-2018 SMD44_RS32920 ba403da06411d650b76d2d97280b5735 267 SUPERFAMILY SSF53167 99 171 1.31E-11 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 SUPERFAMILY SSF48264 21 254 1.44E-94 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 SUPERFAMILY SSF48264 283 489 1.44E-94 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 Pfam PF00067 Cytochrome P450 287 471 7.8E-53 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 Pfam PF00067 Cytochrome P450 47 247 1.4E-13 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00463 E-class P450 group I signature 392 416 1.8E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00463 E-class P450 group I signature 427 437 1.8E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00463 E-class P450 group I signature 437 460 1.8E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00463 E-class P450 group I signature 310 336 1.8E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00463 E-class P450 group I signature 290 307 1.8E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00463 E-class P450 group I signature 44 63 1.8E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00385 P450 superfamily signature 353 364 9.4E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00385 P450 superfamily signature 428 437 9.4E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00385 P450 superfamily signature 301 318 9.4E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 PRINTS PR00385 P450 superfamily signature 437 448 9.4E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 Gene3D G3DSA:1.10.630.10 17 494 2.5E-104 T 28-03-2018 SMD44_RS03295 6400bfdbb0d4ede21945fa7ec6e53c03 494 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 430 439 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 SUPERFAMILY SSF46689 232 277 1.34E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 Gene3D G3DSA:3.40.50.880 1 244 9.1E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 Pfam PF12833 Helix-turn-helix domain 249 327 5.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 SUPERFAMILY SSF52317 2 187 3.35E-33 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 SMART SM00342 243 326 3.4E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 Gene3D G3DSA:1.10.10.60 283 334 2.1E-9 T 28-03-2018 SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 SUPERFAMILY SSF46689 280 332 1.48E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 Pfam PF01965 DJ-1/PfpI family 54 171 5.1E-11 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS12590 3ac2b73feafe2d06077726b838b8257c 343 Gene3D G3DSA:1.10.10.60 245 282 9.1E-12 T 28-03-2018 SMD44_RS09270 7e699d5d5a043929a48bdd1963859836 168 SMART SM00507 71 120 2.0E-11 T 28-03-2018 IPR003615 HNH nuclease SMD44_RS09270 7e699d5d5a043929a48bdd1963859836 168 Gene3D G3DSA:3.40.1800.10 64 136 1.8E-16 T 28-03-2018 SMD44_RS09270 7e699d5d5a043929a48bdd1963859836 168 Pfam PF01844 HNH endonuclease 84 125 3.9E-9 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMD44_RS05325 5849fbf7d89a1e34bfb20ac2f082e000 584 Gene3D G3DSA:1.10.3720.10 295 583 9.1E-25 T 28-03-2018 SMD44_RS05325 5849fbf7d89a1e34bfb20ac2f082e000 584 SUPERFAMILY SSF161098 71 266 6.41E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS05325 5849fbf7d89a1e34bfb20ac2f082e000 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 267 1.1E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS05325 5849fbf7d89a1e34bfb20ac2f082e000 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 399 578 3.0E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS05325 5849fbf7d89a1e34bfb20ac2f082e000 584 SUPERFAMILY SSF161098 381 570 1.83E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS05325 5849fbf7d89a1e34bfb20ac2f082e000 584 Gene3D G3DSA:1.10.3720.10 67 277 8.2E-19 T 28-03-2018 SMD44_RS27225 3bc4ff3c58d46c8f1790eb8e89cae5c3 540 SUPERFAMILY SSF51556 348 476 2.27E-75 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS27225 3bc4ff3c58d46c8f1790eb8e89cae5c3 540 SUPERFAMILY SSF51556 61 303 2.27E-75 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS27225 3bc4ff3c58d46c8f1790eb8e89cae5c3 540 Gene3D G3DSA:2.30.40.10 457 525 7.7E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS27225 3bc4ff3c58d46c8f1790eb8e89cae5c3 540 Pfam PF07969 Amidohydrolase family 50 521 1.3E-66 T 28-03-2018 IPR013108 Amidohydrolase 3 SMD44_RS27225 3bc4ff3c58d46c8f1790eb8e89cae5c3 540 Gene3D G3DSA:2.30.40.10 1 69 2.4E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS27225 3bc4ff3c58d46c8f1790eb8e89cae5c3 540 SUPERFAMILY SSF51338 476 527 1.44E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS27225 3bc4ff3c58d46c8f1790eb8e89cae5c3 540 SUPERFAMILY SSF51338 1 61 1.44E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS27225 3bc4ff3c58d46c8f1790eb8e89cae5c3 540 Gene3D G3DSA:3.20.20.140 70 456 1.1E-87 T 28-03-2018 SMD44_RS37705 6a4d14fb8f84339707a8846c6cb602cf 283 PRINTS PR00412 Epoxide hydrolase signature 29 47 8.0E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS37705 6a4d14fb8f84339707a8846c6cb602cf 283 PRINTS PR00412 Epoxide hydrolase signature 58 73 8.0E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS37705 6a4d14fb8f84339707a8846c6cb602cf 283 PRINTS PR00412 Epoxide hydrolase signature 252 274 8.0E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS37705 6a4d14fb8f84339707a8846c6cb602cf 283 SUPERFAMILY SSF53474 3 276 1.72E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS37705 6a4d14fb8f84339707a8846c6cb602cf 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.9E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS37705 6a4d14fb8f84339707a8846c6cb602cf 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 2.9E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS37705 6a4d14fb8f84339707a8846c6cb602cf 283 Gene3D G3DSA:3.40.50.1820 3 276 8.9E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS37705 6a4d14fb8f84339707a8846c6cb602cf 283 Pfam PF00561 alpha/beta hydrolase fold 23 142 2.0E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 Pfam PF00072 Response regulator receiver domain 8 121 1.2E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 Gene3D G3DSA:3.40.50.2300 5 139 6.5E-39 T 28-03-2018 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 SMART SM00421 159 216 4.9E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 SUPERFAMILY SSF52172 5 193 3.02E-36 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS26075 5983dac7c887607522365706b5b26194 228 SMART SM00448 6 121 1.4E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 Gene3D G3DSA:1.10.10.10 140 221 1.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26075 5983dac7c887607522365706b5b26194 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 3.6E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 5.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 5.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26075 5983dac7c887607522365706b5b26194 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 5.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23445 8ca319dc76f15cd6984c863ab74ba082 320 SUPERFAMILY SSF50129 1 150 6.76E-30 T 28-03-2018 IPR011032 GroES-like SMD44_RS23445 8ca319dc76f15cd6984c863ab74ba082 320 Gene3D G3DSA:3.40.50.720 144 240 5.0E-22 T 28-03-2018 SMD44_RS23445 8ca319dc76f15cd6984c863ab74ba082 320 Gene3D G3DSA:3.90.180.10 1 143 1.8E-34 T 28-03-2018 SMD44_RS23445 8ca319dc76f15cd6984c863ab74ba082 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 3.5E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS23445 8ca319dc76f15cd6984c863ab74ba082 320 SUPERFAMILY SSF51735 114 256 4.51E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS23445 8ca319dc76f15cd6984c863ab74ba082 320 Gene3D G3DSA:3.90.180.10 241 319 8.6E-5 T 28-03-2018 SMD44_RS23445 8ca319dc76f15cd6984c863ab74ba082 320 Pfam PF13602 Zinc-binding dehydrogenase 185 318 1.4E-15 T 28-03-2018 SMD44_RS23445 8ca319dc76f15cd6984c863ab74ba082 320 SMART SM00829 10 318 1.0E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS10605 3eaa651d73e8151822f22e3ac4c8bd36 116 SMART SM00830 31 111 7.8E-23 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS10605 3eaa651d73e8151822f22e3ac4c8bd36 116 Gene3D G3DSA:1.20.59.10 18 116 3.8E-28 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS10605 3eaa651d73e8151822f22e3ac4c8bd36 116 SUPERFAMILY SSF48600 20 110 2.14E-25 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS10605 3eaa651d73e8151822f22e3ac4c8bd36 116 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 23 114 3.0E-50 T 28-03-2018 IPR010951 Chorismate mutase, bacteria SMD44_RS10605 3eaa651d73e8151822f22e3ac4c8bd36 116 Pfam PF01817 Chorismate mutase type II 31 106 6.5E-18 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS38800 b222c51c6b3b2605637c684042cc5be6 341 Gene3D G3DSA:3.90.25.10 175 317 2.8E-15 T 28-03-2018 SMD44_RS38800 b222c51c6b3b2605637c684042cc5be6 341 Gene3D G3DSA:3.40.50.720 1 174 2.5E-19 T 28-03-2018 SMD44_RS38800 b222c51c6b3b2605637c684042cc5be6 341 SUPERFAMILY SSF51735 1 310 5.92E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS38800 b222c51c6b3b2605637c684042cc5be6 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 236 4.8E-40 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS38110 c1ccc24c4fad1d099733570938e9f7cd 296 Gene3D G3DSA:1.10.530.10 91 296 2.7E-67 T 28-03-2018 SMD44_RS38110 c1ccc24c4fad1d099733570938e9f7cd 296 Gene3D G3DSA:2.10.10.20 23 80 3.1E-15 T 28-03-2018 SMD44_RS38110 c1ccc24c4fad1d099733570938e9f7cd 296 PIRSF PIRSF001060 1 296 6.8E-86 T 28-03-2018 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS38110 c1ccc24c4fad1d099733570938e9f7cd 296 Pfam PF00182 Chitinase class I 94 296 6.6E-43 T 28-03-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS38110 c1ccc24c4fad1d099733570938e9f7cd 296 SMART SM00495 34 76 7.5E-12 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD44_RS38110 c1ccc24c4fad1d099733570938e9f7cd 296 SUPERFAMILY SSF51055 25 79 8.24E-16 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD44_RS38110 c1ccc24c4fad1d099733570938e9f7cd 296 SUPERFAMILY SSF53955 93 296 5.62E-69 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS40850 e2e6716482f9f6853779501f40c5c835 264 SMART SM00382 31 224 6.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS40850 e2e6716482f9f6853779501f40c5c835 264 Pfam PF00005 ABC transporter 22 161 6.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS40850 e2e6716482f9f6853779501f40c5c835 264 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS40850 e2e6716482f9f6853779501f40c5c835 264 SUPERFAMILY SSF52540 1 229 2.1E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS40850 e2e6716482f9f6853779501f40c5c835 264 Gene3D G3DSA:3.40.50.300 1 261 9.3E-62 T 28-03-2018 SMD44_RS34025 607cbcbed10371cf8a56a06d9b5fa2a1 530 PIRSF PIRSF002744 29 530 2.6E-45 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMD44_RS34025 607cbcbed10371cf8a56a06d9b5fa2a1 530 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 57 478 7.2E-138 T 28-03-2018 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0005215|GO:0006810|GO:0016020 SMD44_RS34025 607cbcbed10371cf8a56a06d9b5fa2a1 530 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 62 510 2.7E-141 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMD44_RS37485 5dbe7b485f6e9536f62371d8f8e2f37a 455 Gene3D G3DSA:3.20.20.150 312 435 0.0048 T 28-03-2018 SMD44_RS37485 5dbe7b485f6e9536f62371d8f8e2f37a 455 SUPERFAMILY SSF55931 295 424 5.2E-36 T 28-03-2018 SMD44_RS37485 5dbe7b485f6e9536f62371d8f8e2f37a 455 SUPERFAMILY SSF55931 31 256 5.2E-36 T 28-03-2018 SMD44_RS37485 5dbe7b485f6e9536f62371d8f8e2f37a 455 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 26 419 7.2E-136 T 28-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD44_RS37485 5dbe7b485f6e9536f62371d8f8e2f37a 455 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 14 417 32.185 T 28-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD44_RS37485 5dbe7b485f6e9536f62371d8f8e2f37a 455 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 40 346 4.7E-75 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD44_RS37485 5dbe7b485f6e9536f62371d8f8e2f37a 455 PIRSF PIRSF017901 6 438 1.1E-114 T 28-03-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD44_RS19775 a192992b45dd88babfb0263bc763a404 340 PIRSF PIRSF005739 1 340 1.1E-35 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD44_RS19775 a192992b45dd88babfb0263bc763a404 340 Pfam PF00891 O-methyltransferase 105 321 2.7E-28 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD44_RS19775 a192992b45dd88babfb0263bc763a404 340 SUPERFAMILY SSF53335 95 338 4.62E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS19775 a192992b45dd88babfb0263bc763a404 340 Gene3D G3DSA:3.40.50.150 98 340 1.5E-38 T 28-03-2018 SMD44_RS19775 a192992b45dd88babfb0263bc763a404 340 Gene3D G3DSA:1.10.10.10 6 97 2.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19775 a192992b45dd88babfb0263bc763a404 340 SUPERFAMILY SSF46785 9 94 6.46E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22515 c33fad5ee4178c2d40ec43a562fe6e27 271 Gene3D G3DSA:1.10.260.40 1 87 4.2E-8 T 28-03-2018 SMD44_RS10805 3e453b20b7dec2e1224ff385a05c8f28 127 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 14 117 31.712 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMD44_RS10805 3e453b20b7dec2e1224ff385a05c8f28 127 SUPERFAMILY SSF141734 14 116 7.06E-47 T 28-03-2018 SMD44_RS10805 3e453b20b7dec2e1224ff385a05c8f28 127 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 40 112 8.1E-34 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMD44_RS10805 3e453b20b7dec2e1224ff385a05c8f28 127 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 63 112 3.0E-20 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMD44_RS23590 fb941f227b827f95379c614689a56bcb 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 9.6E-26 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23590 fb941f227b827f95379c614689a56bcb 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 19.995 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23590 fb941f227b827f95379c614689a56bcb 78 Pfam PF00830 Ribosomal L28 family 4 60 3.7E-23 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23590 fb941f227b827f95379c614689a56bcb 78 Gene3D G3DSA:2.30.170.40 2 75 1.8E-23 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23590 fb941f227b827f95379c614689a56bcb 78 SUPERFAMILY SSF143800 2 77 9.03E-26 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 PIRSF PIRSF036480 16 297 1.5E-115 T 28-03-2018 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 SUPERFAMILY SSF55021 17 98 2.42E-20 T 28-03-2018 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 Pfam PF00551 Formyl transferase 101 278 1.1E-37 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 SUPERFAMILY SSF53328 101 296 2.62E-64 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 Gene3D G3DSA:3.40.50.170 103 293 5.4E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 16 296 48.499 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 248 270 2.2E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 270 295 2.2E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 21 47 2.2E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 102 124 2.2E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 53 65 2.2E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 124 151 2.2E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 20 296 6.1E-104 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS18130 dc5fcbe248c091fc98bb40e41ac4a121 297 Gene3D G3DSA:3.30.70.260 14 102 2.1E-33 T 28-03-2018 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 PRINTS PR01217 Proline rich extensin signature 206 231 4.4E-10 T 28-03-2018 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 PRINTS PR01217 Proline rich extensin signature 183 200 4.4E-10 T 28-03-2018 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 PRINTS PR01217 Proline rich extensin signature 40 56 4.4E-10 T 28-03-2018 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 PRINTS PR01217 Proline rich extensin signature 155 171 4.4E-10 T 28-03-2018 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 SMART SM00332 263 521 9.1E-7 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 SMART SM00331 272 523 2.5E-4 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 Gene3D G3DSA:2.20.28.20 11 38 2.3E-4 T 28-03-2018 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 Gene3D G3DSA:3.60.40.10 266 523 2.8E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 Pfam PF13672 Protein phosphatase 2C 280 483 1.3E-15 T 28-03-2018 SMD44_RS14505 5f47dfd4531fff7f6776c9b7c3323575 533 SUPERFAMILY SSF81606 268 523 1.09E-38 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 Gene3D G3DSA:3.90.226.10 220 430 3.7E-39 T 28-03-2018 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 Gene3D G3DSA:3.90.226.10 1 219 7.4E-43 T 28-03-2018 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 Pfam PF01039 Carboxyl transferase domain 44 192 6.1E-15 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 Pfam PF01039 Carboxyl transferase domain 308 407 6.9E-10 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 142 159 4.7E-14 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 71 85 4.7E-14 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 182 4.7E-14 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 105 123 4.7E-14 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 SUPERFAMILY SSF52096 229 438 3.64E-46 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS03060 a32a518ddf4786eb797c7c7070ef8717 438 SUPERFAMILY SSF52096 1 218 8.42E-41 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS36155 f2f4583a6ed481769ef98504af433866 733 SUPERFAMILY SSF82866 121 311 5.75E-29 T 28-03-2018 SMD44_RS36155 f2f4583a6ed481769ef98504af433866 733 Gene3D G3DSA:1.20.1640.10 457 688 4.7E-29 T 28-03-2018 SMD44_RS36155 f2f4583a6ed481769ef98504af433866 733 Gene3D G3DSA:1.20.1640.10 74 327 9.3E-32 T 28-03-2018 SMD44_RS36155 f2f4583a6ed481769ef98504af433866 733 Pfam PF03176 MMPL family 27 365 1.1E-68 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS36155 f2f4583a6ed481769ef98504af433866 733 Pfam PF03176 MMPL family 457 691 1.9E-34 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS36155 f2f4583a6ed481769ef98504af433866 733 SUPERFAMILY SSF82866 460 691 4.45E-27 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 Gene3D G3DSA:3.50.50.60 150 186 3.7E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 Gene3D G3DSA:3.40.50.720 1 149 4.4E-13 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 Gene3D G3DSA:3.50.50.60 187 343 1.1E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 3.3E-14 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.3E-14 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 144 3.3E-14 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 3.3E-14 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 SUPERFAMILY SSF51905 4 89 4.15E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 SUPERFAMILY SSF51905 118 351 4.15E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.6E-7 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 1.6E-7 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 1.6E-7 T 28-03-2018 SMD44_RS20365 536ddedc688763fb6f513dd74da6eda4 424 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 327 5.4E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17080 d8d98d7908933c2dcef7441a806bfc04 290 SUPERFAMILY SSF51556 18 289 1.57E-71 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS17080 d8d98d7908933c2dcef7441a806bfc04 290 Pfam PF01026 TatD related DNase 21 288 7.3E-68 T 28-03-2018 IPR001130 TatD family GO:0016788 SMD44_RS17080 d8d98d7908933c2dcef7441a806bfc04 290 Gene3D G3DSA:3.20.20.140 17 290 2.5E-76 T 28-03-2018 SMD44_RS17080 d8d98d7908933c2dcef7441a806bfc04 290 PIRSF PIRSF005902 4 290 5.5E-67 T 28-03-2018 IPR001130 TatD family GO:0016788 SMD44_RS16810 6b8e2f21e81cb5bb8574beb0811d23b2 334 Gene3D G3DSA:3.40.1010.10 13 119 0.0013 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS16810 6b8e2f21e81cb5bb8574beb0811d23b2 334 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 147 222 2.9E-28 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SMD44_RS16810 6b8e2f21e81cb5bb8574beb0811d23b2 334 Gene3D G3DSA:1.10.287.1080 126 244 2.6E-45 T 28-03-2018 SMD44_RS16810 6b8e2f21e81cb5bb8574beb0811d23b2 334 SUPERFAMILY SSF101386 129 225 1.14E-23 T 28-03-2018 SMD44_RS06765 08be7a558992fdf18f6a11e2c186deea 247 Pfam PF01614 Bacterial transcriptional regulator 118 241 4.6E-31 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS06765 08be7a558992fdf18f6a11e2c186deea 247 SUPERFAMILY SSF55781 58 245 3.04E-47 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS06765 08be7a558992fdf18f6a11e2c186deea 247 SUPERFAMILY SSF46785 1 71 8.16E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06765 08be7a558992fdf18f6a11e2c186deea 247 Pfam PF09339 IclR helix-turn-helix domain 3 51 9.6E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS06765 08be7a558992fdf18f6a11e2c186deea 247 SMART SM00346 1 90 4.9E-26 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS06765 08be7a558992fdf18f6a11e2c186deea 247 Gene3D G3DSA:3.30.450.40 73 246 4.3E-47 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS06765 08be7a558992fdf18f6a11e2c186deea 247 Gene3D G3DSA:1.10.10.10 1 61 2.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 Hamap MF_00020 Acetate kinase [ackA]. 1 402 178.216 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 Gene3D G3DSA:3.30.420.40 5 199 5.1E-75 T 28-03-2018 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 TIGRFAM TIGR00016 ackA: acetate kinase 4 398 1.9E-145 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 SUPERFAMILY SSF53067 161 399 2.83E-85 T 28-03-2018 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 207 224 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 Gene3D G3DSA:3.30.420.40 200 402 3.9E-82 T 28-03-2018 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 SUPERFAMILY SSF53067 5 200 1.88E-63 T 28-03-2018 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 PIRSF PIRSF000722 2 402 6.5E-146 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 PRINTS PR00471 Acetate kinase family signature 207 228 9.1E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 PRINTS PR00471 Acetate kinase family signature 6 17 9.1E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 PRINTS PR00471 Acetate kinase family signature 177 190 9.1E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 PRINTS PR00471 Acetate kinase family signature 303 316 9.1E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 PRINTS PR00471 Acetate kinase family signature 380 392 9.1E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 PRINTS PR00471 Acetate kinase family signature 325 341 9.1E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS29225 1a0a6a8d9374f470ec3c9fb06c1755c3 403 Pfam PF00871 Acetokinase family 6 392 2.3E-150 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD44_RS34200 e3060accc401a5ceb06b0b46780c824e 301 Pfam PF00440 Bacterial regulatory proteins, tetR family 71 110 4.4E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS34200 e3060accc401a5ceb06b0b46780c824e 301 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 90 113 1.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS34200 e3060accc401a5ceb06b0b46780c824e 301 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 69 82 1.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS34200 e3060accc401a5ceb06b0b46780c824e 301 ProSitePatterns PS01081 TetR-type HTH domain signature. 81 112 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS34200 e3060accc401a5ceb06b0b46780c824e 301 SUPERFAMILY SSF46689 59 113 5.2E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS34200 e3060accc401a5ceb06b0b46780c824e 301 Gene3D G3DSA:1.10.10.60 35 118 6.0E-19 T 28-03-2018 SMD44_RS34200 e3060accc401a5ceb06b0b46780c824e 301 Gene3D G3DSA:1.10.357.10 119 253 6.0E-30 T 28-03-2018 SMD44_RS28905 1b0cac8f56fd63e9f7cede1826efada0 152 Pfam PF10739 Protein of unknown function (DUF2550) 14 146 7.2E-43 T 28-03-2018 IPR019675 Protein of unknown function DUF2550 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 Hamap MF_01228 Methionine--tRNA ligase [metG]. 6 529 46.312 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 Pfam PF09334 tRNA synthetases class I (M) 17 379 3.5E-105 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 SUPERFAMILY SSF52374 16 364 1.33E-103 T 28-03-2018 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 18 501 3.6E-149 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 Gene3D G3DSA:3.40.50.620 14 363 7.1E-93 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 SUPERFAMILY SSF47323 368 535 3.6E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 Gene3D G3DSA:1.10.730.10 364 535 4.5E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 PRINTS PR01041 Methionyl-tRNA synthetase signature 367 378 2.5E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 PRINTS PR01041 Methionyl-tRNA synthetase signature 243 254 2.5E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 PRINTS PR01041 Methionyl-tRNA synthetase signature 275 290 2.5E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 PRINTS PR01041 Methionyl-tRNA synthetase signature 51 65 2.5E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 PRINTS PR01041 Methionyl-tRNA synthetase signature 100 111 2.5E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS21970 35475150f1debf5bc7c11274504be950 542 PRINTS PR01041 Methionyl-tRNA synthetase signature 19 32 2.5E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 22 96 1.7E-18 T 28-03-2018 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 SMART SM00926 239 293 3.2E-7 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 169 179 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 52 69 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Gene3D G3DSA:3.40.50.740 298 461 3.0E-24 T 28-03-2018 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Gene3D G3DSA:2.40.40.20 743 825 9.3E-16 T 28-03-2018 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 SUPERFAMILY SSF54292 23 94 3.99E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 140 2.8E-16 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Pfam PF01568 Molydopterin dinucleotide binding domain 750 817 1.6E-6 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Gene3D G3DSA:3.40.50.740 462 703 2.6E-35 T 28-03-2018 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Pfam PF00384 Molybdopterin oxidoreductase 573 663 1.2E-7 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Pfam PF00384 Molybdopterin oxidoreductase 296 442 2.9E-13 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 SUPERFAMILY SSF54862 99 234 1.88E-31 T 28-03-2018 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Gene3D G3DSA:2.20.25.90 236 297 7.2E-11 T 28-03-2018 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 SUPERFAMILY SSF50692 726 807 4.59E-7 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 SUPERFAMILY SSF53706 230 699 1.21E-84 T 28-03-2018 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 121 133 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 SMART SM00929 106 146 3.7E-19 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 243 291 2.5E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 Gene3D G3DSA:3.10.20.30 15 184 1.2E-15 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS25050 6e16aad4b30ecffc0d4373a0143a2ded 837 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 25 676 1.0E-193 T 28-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS09815 3f18f5c30246f094bad3c3365e474ecb 451 Gene3D G3DSA:3.40.50.1820 62 449 5.4E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS09815 3f18f5c30246f094bad3c3365e474ecb 451 SUPERFAMILY SSF53474 84 221 5.53E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS09815 3f18f5c30246f094bad3c3365e474ecb 451 SUPERFAMILY SSF53474 370 444 5.53E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS09815 3f18f5c30246f094bad3c3365e474ecb 451 Pfam PF05576 PS-10 peptidase S37 41 450 9.6E-124 T 28-03-2018 IPR008761 Peptidase S37, tripeptidyl aminopeptidase SMD44_RS13560 e4f147d51de0b764b908367fbcea5869 275 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 SMD44_RS13560 e4f147d51de0b764b908367fbcea5869 275 SUPERFAMILY SSF64005 36 259 5.62E-85 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS13560 e4f147d51de0b764b908367fbcea5869 275 Gene3D G3DSA:3.40.1180.10 27 266 6.7E-86 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS13560 e4f147d51de0b764b908367fbcea5869 275 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 36 263 2.9E-79 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS13560 e4f147d51de0b764b908367fbcea5869 275 Pfam PF01255 Putative undecaprenyl diphosphate synthase 43 263 1.1E-74 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS13560 e4f147d51de0b764b908367fbcea5869 275 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 36 264 38.59 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 51 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 Gene3D G3DSA:1.10.730.10 318 486 0.0015 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 215 579 5.5E-52 T 28-03-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 Gene3D G3DSA:3.40.50.620 10 317 5.7E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 SUPERFAMILY SSF52374 213 363 1.66E-48 T 28-03-2018 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 SUPERFAMILY SSF52374 26 176 1.66E-48 T 28-03-2018 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 Pfam PF01921 tRNA synthetases class I (K) 12 401 2.7E-127 T 28-03-2018 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 11 582 31.055 T 28-03-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 SUPERFAMILY SSF48163 369 580 9.42E-22 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD44_RS24200 2d02b4e2b13bb5eda909e413869deb97 582 Gene3D G3DSA:1.10.10.350 487 582 5.3E-11 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD44_RS05125 f23f9562f204c69f7e6e9d566d4a92b1 388 Pfam PF00266 Aminotransferase class-V 9 333 5.8E-39 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS05125 f23f9562f204c69f7e6e9d566d4a92b1 388 Gene3D G3DSA:3.90.1150.10 273 387 3.0E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS05125 f23f9562f204c69f7e6e9d566d4a92b1 388 SUPERFAMILY SSF53383 6 370 3.25E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS05125 f23f9562f204c69f7e6e9d566d4a92b1 388 Gene3D G3DSA:3.40.640.10 16 272 1.7E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS05125 f23f9562f204c69f7e6e9d566d4a92b1 388 PIRSF PIRSF000524 1 386 1.5E-130 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 SMD44_RS36615 014102cd363c61fcc7e6af4db1d765f8 212 Pfam PF08281 Sigma-70, region 4 145 193 6.5E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS36615 014102cd363c61fcc7e6af4db1d765f8 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 199 1.0E-18 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS36615 014102cd363c61fcc7e6af4db1d765f8 212 Gene3D G3DSA:1.10.1740.10 29 116 3.2E-20 T 28-03-2018 SMD44_RS36615 014102cd363c61fcc7e6af4db1d765f8 212 Gene3D G3DSA:1.10.10.10 117 202 9.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36615 014102cd363c61fcc7e6af4db1d765f8 212 Pfam PF04542 Sigma-70 region 2 52 115 1.8E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS36615 014102cd363c61fcc7e6af4db1d765f8 212 SUPERFAMILY SSF88659 134 199 7.29E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS36615 014102cd363c61fcc7e6af4db1d765f8 212 SUPERFAMILY SSF88946 34 118 4.32E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 Pfam PF01839 FG-GAP repeat 101 138 5.1E-9 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 Pfam PF01839 FG-GAP repeat 38 66 2.0E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 Pfam PF01839 FG-GAP repeat 266 285 3.9E-6 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 Gene3D G3DSA:2.60.40.680 109 189 1.5E-14 T 28-03-2018 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 Gene3D G3DSA:2.60.40.680 14 108 8.2E-19 T 28-03-2018 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 Gene3D G3DSA:2.130.10.130 321 475 3.1E-14 T 28-03-2018 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 Gene3D G3DSA:2.130.10.130 198 320 1.2E-8 T 28-03-2018 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 SUPERFAMILY SSF69318 38 437 7.46E-48 T 28-03-2018 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 SMART SM00191 16 85 83.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 SMART SM00191 260 329 46.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 SMART SM00191 97 151 0.63 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 SMART SM00191 154 211 150.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 SMART SM00191 408 459 1.5 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22430 01df3472090d5efebd7726c1b45ac1d5 477 SMART SM00191 339 397 8.8 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS00295 39862fc12d4013269ab2f5da4f7925cc 345 Gene3D G3DSA:3.30.1370.60 75 301 6.3E-70 T 28-03-2018 SMD44_RS00295 39862fc12d4013269ab2f5da4f7925cc 345 Pfam PF02615 Malate/L-lactate dehydrogenase 3 328 1.2E-97 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 SMD44_RS00295 39862fc12d4013269ab2f5da4f7925cc 345 Gene3D G3DSA:1.10.1530.10 1 74 8.5E-22 T 28-03-2018 SMD44_RS00295 39862fc12d4013269ab2f5da4f7925cc 345 SUPERFAMILY SSF89733 2 337 5.49E-91 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 SMD44_RS02395 9dccf8169c367ef48e09cbd0e8dcc89d 428 SUPERFAMILY SSF52540 144 388 5.48E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS02395 9dccf8169c367ef48e09cbd0e8dcc89d 428 Gene3D G3DSA:1.25.40.10 5 113 6.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS02395 9dccf8169c367ef48e09cbd0e8dcc89d 428 ProSitePatterns PS00674 AAA-protein family signature. 286 304 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMD44_RS02395 9dccf8169c367ef48e09cbd0e8dcc89d 428 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 184 312 1.3E-39 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS02395 9dccf8169c367ef48e09cbd0e8dcc89d 428 Gene3D G3DSA:1.10.8.60 326 396 9.0E-17 T 28-03-2018 SMD44_RS02395 9dccf8169c367ef48e09cbd0e8dcc89d 428 SMART SM00382 180 318 1.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS02395 9dccf8169c367ef48e09cbd0e8dcc89d 428 SUPERFAMILY SSF48452 9 67 3.8E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS02395 9dccf8169c367ef48e09cbd0e8dcc89d 428 Gene3D G3DSA:3.40.50.300 131 325 4.2E-53 T 28-03-2018 SMD44_RS25125 b59db7635006f226000545079de6aff8 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 236 1.9E-19 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SMD44_RS25125 b59db7635006f226000545079de6aff8 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 9 263 6.1E-45 T 28-03-2018 IPR000150 Cof family GO:0016787 SMD44_RS25125 b59db7635006f226000545079de6aff8 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 10 263 2.1E-47 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS25125 b59db7635006f226000545079de6aff8 268 SUPERFAMILY SSF56784 7 267 3.9E-58 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS25125 b59db7635006f226000545079de6aff8 268 Gene3D G3DSA:3.40.50.1000 7 267 1.9E-35 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 Gene3D G3DSA:1.10.10.10 127 208 4.7E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 Pfam PF00072 Response regulator receiver domain 4 115 2.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 SMART SM00448 2 115 1.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 SMART SM00421 143 200 3.1E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 SUPERFAMILY SSF46894 128 206 3.37E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 1.5E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 Gene3D G3DSA:3.40.50.2300 1 126 4.6E-36 T 28-03-2018 SMD44_RS07395 f9222aebe9a92eeb97c38a0817b933f5 208 SUPERFAMILY SSF52172 2 133 2.13E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 Pfam PF02311 AraC-like ligand binding domain 17 146 1.5E-22 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 SUPERFAMILY SSF46689 172 221 2.87E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 SUPERFAMILY SSF51215 30 139 1.15E-19 T 28-03-2018 SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 Gene3D G3DSA:1.10.10.60 230 278 1.4E-12 T 28-03-2018 SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 Pfam PF12833 Helix-turn-helix domain 193 270 2.1E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 SUPERFAMILY SSF46689 224 273 5.38E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 Gene3D G3DSA:1.10.10.60 153 229 3.1E-12 T 28-03-2018 SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 Gene3D G3DSA:2.60.120.280 18 152 8.8E-12 T 28-03-2018 SMD44_RS31180 354c29e76b12e65e9134a8cc34e74138 338 SMART SM00342 187 269 4.9E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS19005 16f4e0396eb8d6dfacaef48308499fab 257 Gene3D G3DSA:3.90.550.10 7 255 1.2E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS19005 16f4e0396eb8d6dfacaef48308499fab 257 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 22 248 6.2E-70 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMD44_RS19005 16f4e0396eb8d6dfacaef48308499fab 257 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 21 249 1.6E-64 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMD44_RS19005 16f4e0396eb8d6dfacaef48308499fab 257 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 120 127 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMD44_RS19005 16f4e0396eb8d6dfacaef48308499fab 257 SUPERFAMILY SSF53448 20 248 1.62E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS19005 16f4e0396eb8d6dfacaef48308499fab 257 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 19 248 40.111 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 72 327 8.6E-69 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 52 462 39.361 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 228 241 4.1E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 419 432 4.1E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 111 4.1E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 113 125 4.1E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 317 336 4.1E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 333 419 1.8E-14 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 Gene3D G3DSA:2.40.37.10 313 462 1.2E-39 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 42 461 1.1E-143 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 SUPERFAMILY SSF50621 302 462 8.58E-48 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 111 128 8.3E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 346 364 8.3E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 429 451 8.3E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 200 209 8.3E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 267 280 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 SUPERFAMILY SSF51419 63 328 1.34E-78 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 93 111 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site SMD44_RS28795 00cfde7a18912a09539dd2486ea7e9a0 463 Gene3D G3DSA:3.20.20.10 71 312 9.6E-68 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS23255 e86d7ec91001678ea800dcd92a133520 274 SUPERFAMILY SSF56784 11 230 1.43E-32 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS23255 e86d7ec91001678ea800dcd92a133520 274 Gene3D G3DSA:3.40.50.1000 14 236 1.1E-19 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS23255 e86d7ec91001678ea800dcd92a133520 274 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 14 214 3.2E-61 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like SMD44_RS23255 e86d7ec91001678ea800dcd92a133520 274 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 14 203 1.0E-21 T 28-03-2018 SMD44_RS23255 e86d7ec91001678ea800dcd92a133520 274 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 201 4.2E-31 T 28-03-2018 SMD44_RS33220 40fe87d37a1eb2d864d59558dee39678 166 Gene3D G3DSA:1.10.10.10 1 162 4.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33220 40fe87d37a1eb2d864d59558dee39678 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 6.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS33220 40fe87d37a1eb2d864d59558dee39678 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 6.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS33220 40fe87d37a1eb2d864d59558dee39678 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 6.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS33220 40fe87d37a1eb2d864d59558dee39678 166 Pfam PF12802 MarR family 48 110 2.2E-10 T 28-03-2018 SMD44_RS33220 40fe87d37a1eb2d864d59558dee39678 166 SUPERFAMILY SSF46785 10 159 7.08E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33220 40fe87d37a1eb2d864d59558dee39678 166 SMART SM00347 43 146 1.3E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 Gene3D G3DSA:3.40.50.1360 72 246 7.8E-41 T 28-03-2018 SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 SUPERFAMILY SSF100950 74 241 1.44E-25 T 28-03-2018 SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 SMART SM01134 72 240 7.6E-61 T 28-03-2018 SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 Pfam PF00455 DeoR C terminal sensor domain 74 239 4.0E-50 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 SUPERFAMILY SSF46785 4 66 5.02E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 Gene3D G3DSA:1.10.10.10 1 69 8.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 SMART SM00420 6 58 2.1E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 9.0E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS02665 b26c30a6ec0ce7b9d4804a874296fd7d 259 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 82 92 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 PRINTS PR00985 Leucyl-tRNA synthetase signature 619 637 1.2E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 PRINTS PR00985 Leucyl-tRNA synthetase signature 667 689 1.2E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 PRINTS PR00985 Leucyl-tRNA synthetase signature 240 256 1.2E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 PRINTS PR00985 Leucyl-tRNA synthetase signature 700 710 1.2E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 PRINTS PR00985 Leucyl-tRNA synthetase signature 302 321 1.2E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 PRINTS PR00985 Leucyl-tRNA synthetase signature 273 286 1.2E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 PRINTS PR00985 Leucyl-tRNA synthetase signature 166 183 1.2E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 SUPERFAMILY SSF52374 37 186 2.1E-113 T 28-03-2018 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 SUPERFAMILY SSF52374 533 798 2.1E-113 T 28-03-2018 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 SUPERFAMILY SSF52374 235 313 2.1E-113 T 28-03-2018 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 235 977 9.9E-216 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 308 521 1.0E-56 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 Gene3D G3DSA:1.10.730.10 779 915 7.8E-26 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 Gene3D G3DSA:3.40.50.620 501 778 7.7E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 Pfam PF09334 tRNA synthetases class I (M) 79 181 1.3E-12 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 SUPERFAMILY SSF50677 310 536 1.26E-43 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 Gene3D G3DSA:3.40.50.620 31 416 2.5E-84 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 Pfam PF08264 Anticodon-binding domain of tRNA 826 939 1.9E-15 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 SUPERFAMILY SSF47323 794 977 9.72E-30 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS13885 aed94fe2e0d825788e679a2631278a6f 979 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 32 978 21.311 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 SUPERFAMILY SSF55545 45 172 7.98E-14 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 177 485 3.4E-35 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 SUPERFAMILY SSF51445 175 514 1.39E-69 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 Gene3D G3DSA:3.30.379.10 45 162 5.9E-15 T 28-03-2018 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 Gene3D G3DSA:3.20.20.80 163 529 2.7E-73 T 28-03-2018 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 51 170 4.7E-14 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 464 480 4.1E-19 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 309 322 4.1E-19 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 136 156 4.1E-19 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 245 262 4.1E-19 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS26600 3df977ae9fe1ad34f90891d47573176c 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 168 185 4.1E-19 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS28825 3a3970ad333d8fc219f98d59a6c9c613 74 SUPERFAMILY SSF143800 1 66 2.55E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS28825 3a3970ad333d8fc219f98d59a6c9c613 74 Pfam PF01197 Ribosomal protein L31 2 66 1.4E-29 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS28825 3a3970ad333d8fc219f98d59a6c9c613 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 2.2E-32 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS28825 3a3970ad333d8fc219f98d59a6c9c613 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 28.481 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS28825 3a3970ad333d8fc219f98d59a6c9c613 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS28825 3a3970ad333d8fc219f98d59a6c9c613 74 PRINTS PR01249 Ribosomal protein L31 signature 47 65 1.6E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS28825 3a3970ad333d8fc219f98d59a6c9c613 74 PRINTS PR01249 Ribosomal protein L31 signature 32 47 1.6E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS28825 3a3970ad333d8fc219f98d59a6c9c613 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.6E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS22065 2006855112c587d455c251d64d6a1c06 352 Gene3D G3DSA:3.40.50.300 15 304 1.3E-60 T 28-03-2018 SMD44_RS22065 2006855112c587d455c251d64d6a1c06 352 Pfam PF00005 ABC transporter 33 175 1.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS22065 2006855112c587d455c251d64d6a1c06 352 SMART SM00382 41 230 6.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS22065 2006855112c587d455c251d64d6a1c06 352 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS22065 2006855112c587d455c251d64d6a1c06 352 SUPERFAMILY SSF52540 16 238 6.16E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22065 2006855112c587d455c251d64d6a1c06 352 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 24 328 2.4E-110 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 SUPERFAMILY SSF53901 257 383 4.2E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 Gene3D G3DSA:3.40.47.10 148 389 1.2E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 Pfam PF00108 Thiolase, N-terminal domain 5 228 5.1E-22 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 Gene3D G3DSA:3.40.47.10 7 132 3.6E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 ProSitePatterns PS00737 Thiolases signature 2. 334 350 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 Pfam PF02803 Thiolase, C-terminal domain 272 369 9.0E-11 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 SUPERFAMILY SSF53901 4 236 4.32E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 77 95 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SMD44_RS12290 5c817313842ddb1d1caa014f097c376a 397 PIRSF PIRSF000429 2 393 3.7E-70 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS31270 d7b313a87711edbf15e6371ef0367543 258 Gene3D G3DSA:3.40.50.300 13 257 2.8E-76 T 28-03-2018 SMD44_RS31270 d7b313a87711edbf15e6371ef0367543 258 Pfam PF00005 ABC transporter 33 181 3.3E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS31270 d7b313a87711edbf15e6371ef0367543 258 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS31270 d7b313a87711edbf15e6371ef0367543 258 SUPERFAMILY SSF52540 18 251 1.03E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31270 d7b313a87711edbf15e6371ef0367543 258 PIRSF PIRSF039085 14 257 1.8E-112 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMD44_RS31270 d7b313a87711edbf15e6371ef0367543 258 SMART SM00382 42 229 1.5E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 SUPERFAMILY SSF102114 18 321 4.71E-77 T 28-03-2018 SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 Pfam PF04055 Radical SAM superfamily 65 220 2.9E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 Gene3D G3DSA:3.20.20.70 14 325 6.6E-53 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 6.4E-14 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 SMART SM00876 232 322 6.2E-32 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 SMART SM00729 55 261 2.5E-38 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 PIRSF PIRSF001619 3 329 1.1E-104 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 Hamap MF_01694 Biotin synthase [bioB]. 15 323 39.214 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD44_RS05825 740675c63209b1c60ab417f74577f4f9 396 TIGRFAM TIGR00433 bioB: biotin synthase 28 321 3.4E-112 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD44_RS33375 c8eea02629c9ff4e3727495cc097a0e1 455 TIGRFAM TIGR03173 pbuX: xanthine permease 5 416 3.7E-158 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 SMD44_RS33375 c8eea02629c9ff4e3727495cc097a0e1 455 Pfam PF00860 Permease family 3 383 1.5E-91 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS33375 c8eea02629c9ff4e3727495cc097a0e1 455 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 331 351 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SMD44_RS33375 c8eea02629c9ff4e3727495cc097a0e1 455 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 3 414 5.2E-106 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SMD44_RS29805 db4b83ec5541590631e148db6bc92bd3 335 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 7 328 1.4E-10 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD44_RS29805 db4b83ec5541590631e148db6bc92bd3 335 Gene3D G3DSA:3.20.20.210 41 335 9.8E-56 T 28-03-2018 SMD44_RS29805 db4b83ec5541590631e148db6bc92bd3 335 SUPERFAMILY SSF51726 59 331 5.23E-31 T 28-03-2018 SMD44_RS25220 9b10401af3f353bb67b8f0963c057fcf 345 SUPERFAMILY SSF103481 55 150 1.01E-11 T 28-03-2018 SMD44_RS25220 9b10401af3f353bb67b8f0963c057fcf 345 SUPERFAMILY SSF103481 194 292 4.71E-12 T 28-03-2018 SMD44_RS25220 9b10401af3f353bb67b8f0963c057fcf 345 TIGRFAM TIGR00688 rarD: protein RarD 15 263 5.1E-62 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 SMD44_RS25220 9b10401af3f353bb67b8f0963c057fcf 345 Pfam PF00892 EamA-like transporter family 13 147 1.5E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS25220 9b10401af3f353bb67b8f0963c057fcf 345 Pfam PF00892 EamA-like transporter family 158 288 1.9E-6 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS12545 a2f50d366c0533826aed3ce2dfd654fe 180 SUPERFAMILY SSF49329 58 171 1.83E-12 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD44_RS12545 a2f50d366c0533826aed3ce2dfd654fe 180 Gene3D G3DSA:2.60.40.200 53 177 1.8E-14 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD44_RS12545 a2f50d366c0533826aed3ce2dfd654fe 180 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 57 171 7.0E-9 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD44_RS12545 a2f50d366c0533826aed3ce2dfd654fe 180 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 163 174 - T 28-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD44_RS10555 d1fd9d09abaa192a80ceb2dacaa6ab96 217 SMART SM01012 151 206 8.6E-24 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS10555 d1fd9d09abaa192a80ceb2dacaa6ab96 217 Gene3D G3DSA:1.10.10.10 165 208 7.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10555 d1fd9d09abaa192a80ceb2dacaa6ab96 217 PIRSF PIRSF036382 15 213 1.5E-70 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator SMD44_RS10555 d1fd9d09abaa192a80ceb2dacaa6ab96 217 Gene3D G3DSA:3.40.50.2300 22 164 7.8E-37 T 28-03-2018 SMD44_RS10555 d1fd9d09abaa192a80ceb2dacaa6ab96 217 Pfam PF03861 ANTAR domain 154 206 1.6E-20 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS10555 d1fd9d09abaa192a80ceb2dacaa6ab96 217 Pfam PF00072 Response regulator receiver domain 26 135 3.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS10555 d1fd9d09abaa192a80ceb2dacaa6ab96 217 SUPERFAMILY SSF52172 23 206 6.69E-56 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS10555 d1fd9d09abaa192a80ceb2dacaa6ab96 217 SMART SM00448 24 135 1.0E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS15610 9b99bd00b27ab2635b2f412f1c357e75 200 Gene3D G3DSA:3.90.950.10 1 198 5.1E-77 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SMD44_RS15610 9b99bd00b27ab2635b2f412f1c357e75 200 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 45.434 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 SMD44_RS15610 9b99bd00b27ab2635b2f412f1c357e75 200 SUPERFAMILY SSF52972 1 196 2.88E-64 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SMD44_RS15610 9b99bd00b27ab2635b2f412f1c357e75 200 Pfam PF01725 Ham1 family 4 192 2.4E-54 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 SMD44_RS15610 9b99bd00b27ab2635b2f412f1c357e75 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 2.2E-50 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 SMD44_RS26460 ca83fbe7f0b16f3d4704d21d7823b7ca 155 Pfam PF04138 GtrA-like protein 11 132 3.9E-21 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMD44_RS10500 618155101675353e69e09f67d29a0319 929 SUPERFAMILY SSF52540 20 180 4.12E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10500 618155101675353e69e09f67d29a0319 929 SUPERFAMILY SSF52540 207 361 4.12E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10500 618155101675353e69e09f67d29a0319 929 Pfam PF00271 Helicase conserved C-terminal domain 235 350 5.9E-10 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS10500 618155101675353e69e09f67d29a0319 929 Pfam PF08482 ATP-dependent helicase C-terminal 778 910 6.8E-49 T 28-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal SMD44_RS10500 618155101675353e69e09f67d29a0319 929 Pfam PF04408 Helicase associated domain (HA2) 413 473 1.0E-6 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 SMD44_RS10500 618155101675353e69e09f67d29a0319 929 Gene3D G3DSA:3.40.50.300 8 180 9.0E-19 T 28-03-2018 SMD44_RS10500 618155101675353e69e09f67d29a0319 929 SMART SM00487 3 204 9.7E-16 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS10500 618155101675353e69e09f67d29a0319 929 SMART SM00847 412 506 3.0E-5 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 SMD44_RS10500 618155101675353e69e09f67d29a0319 929 Gene3D G3DSA:3.40.50.300 198 369 3.1E-33 T 28-03-2018 SMD44_RS10500 618155101675353e69e09f67d29a0319 929 SMART SM00490 254 352 1.1E-9 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS13520 ec095b087eb28e21bbf6cfef772a1980 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS13520 ec095b087eb28e21bbf6cfef772a1980 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS13520 ec095b087eb28e21bbf6cfef772a1980 194 Gene3D G3DSA:1.10.260.40 41 64 1.0E-8 T 28-03-2018 SMD44_RS13520 ec095b087eb28e21bbf6cfef772a1980 194 SUPERFAMILY SSF48498 81 193 6.15E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS13520 ec095b087eb28e21bbf6cfef772a1980 194 Gene3D G3DSA:1.10.10.60 2 40 1.9E-14 T 28-03-2018 SMD44_RS13520 ec095b087eb28e21bbf6cfef772a1980 194 SUPERFAMILY SSF46689 6 84 4.84E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS13520 ec095b087eb28e21bbf6cfef772a1980 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 4.1E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS13520 ec095b087eb28e21bbf6cfef772a1980 194 Gene3D G3DSA:1.10.357.10 65 194 1.1E-18 T 28-03-2018 SMD44_RS33515 e786d72ef92a495d553ac643e5c00836 100 Pfam PF10262 Rdx family 15 87 2.8E-28 T 28-03-2018 IPR011893 Selenoprotein, Rdx type SMD44_RS33515 e786d72ef92a495d553ac643e5c00836 100 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 16 86 1.2E-20 T 28-03-2018 IPR011893 Selenoprotein, Rdx type SMD44_RS33515 e786d72ef92a495d553ac643e5c00836 100 Gene3D G3DSA:3.40.30.10 4 100 5.6E-36 T 28-03-2018 SMD44_RS33515 e786d72ef92a495d553ac643e5c00836 100 SUPERFAMILY SSF52833 14 96 3.58E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS20460 8e54339033f2b5cee44435314a3e8ccb 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 384 3.1E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS20460 8e54339033f2b5cee44435314a3e8ccb 395 Gene3D G3DSA:1.20.140.10 215 395 1.0E-33 T 28-03-2018 SMD44_RS20460 8e54339033f2b5cee44435314a3e8ccb 395 SUPERFAMILY SSF56645 5 239 3.53E-60 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS20460 8e54339033f2b5cee44435314a3e8ccb 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 114 5.9E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS20460 8e54339033f2b5cee44435314a3e8ccb 395 Gene3D G3DSA:2.40.110.10 119 214 3.9E-34 T 28-03-2018 SMD44_RS20460 8e54339033f2b5cee44435314a3e8ccb 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 209 2.7E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS20460 8e54339033f2b5cee44435314a3e8ccb 395 SUPERFAMILY SSF47203 227 391 7.57E-23 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS20460 8e54339033f2b5cee44435314a3e8ccb 395 Gene3D G3DSA:1.10.540.10 1 118 7.7E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS02920 f8b9809f95070c7ebcce3b2d1ce05111 202 Gene3D G3DSA:1.10.10.60 2 43 3.7E-13 T 28-03-2018 SMD44_RS02920 f8b9809f95070c7ebcce3b2d1ce05111 202 SUPERFAMILY SSF46689 9 79 4.99E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS02920 f8b9809f95070c7ebcce3b2d1ce05111 202 Gene3D G3DSA:1.10.357.10 73 202 3.3E-14 T 28-03-2018 SMD44_RS02920 f8b9809f95070c7ebcce3b2d1ce05111 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 1.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02920 f8b9809f95070c7ebcce3b2d1ce05111 202 Gene3D G3DSA:1.10.260.40 44 72 1.8E-11 T 28-03-2018 SMD44_RS02920 f8b9809f95070c7ebcce3b2d1ce05111 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02920 f8b9809f95070c7ebcce3b2d1ce05111 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 4.8E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.8E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 4.8E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 4.8E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 4.8E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 Pfam PF00106 short chain dehydrogenase 8 185 9.8E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 SUPERFAMILY SSF51735 3 244 3.84E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS08525 1a6471b615e27e32c38cb47309d27d5c 254 Gene3D G3DSA:3.40.50.720 1 253 3.2E-43 T 28-03-2018 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 SUPERFAMILY SSF54292 202 304 2.88E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 231 295 6.6E-11 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 SUPERFAMILY SSF63380 4 97 4.54E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 Gene3D G3DSA:2.40.30.10 2 97 3.2E-16 T 28-03-2018 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 PRINTS PR00409 Phthalate dioxygenase reductase family signature 108 127 4.0E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 PRINTS PR00409 Phthalate dioxygenase reductase family signature 49 63 4.0E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 PRINTS PR00409 Phthalate dioxygenase reductase family signature 27 37 4.0E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 PRINTS PR00409 Phthalate dioxygenase reductase family signature 37 49 4.0E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 PRINTS PR00409 Phthalate dioxygenase reductase family signature 184 192 4.0E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 PRINTS PR00409 Phthalate dioxygenase reductase family signature 73 87 4.0E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 Gene3D G3DSA:3.40.50.80 98 210 3.7E-18 T 28-03-2018 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 Pfam PF00175 Oxidoreductase NAD-binding domain 109 198 9.8E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 SUPERFAMILY SSF52343 95 216 1.83E-24 T 28-03-2018 SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 Gene3D G3DSA:3.10.20.30 211 304 3.6E-17 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS01845 0474fe01ea34dc2a9728037a3c05e007 304 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 258 266 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD44_RS36670 f0e9757885bcfaf125905d5370408b08 659 Gene3D G3DSA:1.20.1560.10 11 328 9.1E-14 T 28-03-2018 SMD44_RS36670 f0e9757885bcfaf125905d5370408b08 659 SMART SM00382 379 577 7.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS36670 f0e9757885bcfaf125905d5370408b08 659 SUPERFAMILY SSF52540 346 584 3.52E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS36670 f0e9757885bcfaf125905d5370408b08 659 Pfam PF00005 ABC transporter 370 524 1.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS36670 f0e9757885bcfaf125905d5370408b08 659 SUPERFAMILY SSF90123 24 317 4.19E-15 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS36670 f0e9757885bcfaf125905d5370408b08 659 SUPERFAMILY SSF90123 500 508 4.19E-15 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS36670 f0e9757885bcfaf125905d5370408b08 659 Gene3D G3DSA:3.40.50.300 350 652 2.3E-62 T 28-03-2018 SMD44_RS36670 f0e9757885bcfaf125905d5370408b08 659 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 532 6.3E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 6.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 486 6.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 6.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 530 6.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 Pfam PF00672 HAMP domain 249 297 1.8E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 Gene3D G3DSA:1.10.287.130 299 372 1.5E-14 T 28-03-2018 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 SUPERFAMILY SSF55874 366 535 1.44E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 Gene3D G3DSA:3.30.565.10 380 538 1.2E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 SMART SM00388 309 376 2.4E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 SMART SM00387 422 533 5.0E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 SUPERFAMILY SSF158472 249 297 2.75E-7 T 28-03-2018 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 SUPERFAMILY SSF47384 294 376 2.94E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 SMART SM00304 249 301 1.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS16295 7558568ec49caaa8ddc4f3423dc2a4c0 715 Pfam PF00512 His Kinase A (phospho-acceptor) domain 309 376 5.8E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS08230 fbd0fdccf665f91b91da58dc883bdff5 254 Gene3D G3DSA:3.30.450.40 75 254 2.8E-48 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS08230 fbd0fdccf665f91b91da58dc883bdff5 254 Pfam PF01614 Bacterial transcriptional regulator 123 247 6.5E-32 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS08230 fbd0fdccf665f91b91da58dc883bdff5 254 Pfam PF09339 IclR helix-turn-helix domain 7 57 4.2E-17 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS08230 fbd0fdccf665f91b91da58dc883bdff5 254 SMART SM00346 5 95 4.7E-35 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS08230 fbd0fdccf665f91b91da58dc883bdff5 254 SUPERFAMILY SSF55781 71 250 1.44E-36 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS08230 fbd0fdccf665f91b91da58dc883bdff5 254 SUPERFAMILY SSF46785 5 77 3.68E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08230 fbd0fdccf665f91b91da58dc883bdff5 254 Gene3D G3DSA:1.10.10.10 1 74 3.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21530 dab0a0dd59e3cf45dc6e347e8c8daaee 300 SUPERFAMILY SSF52540 126 264 2.03E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21530 dab0a0dd59e3cf45dc6e347e8c8daaee 300 SUPERFAMILY SSF52540 1 52 2.03E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21530 dab0a0dd59e3cf45dc6e347e8c8daaee 300 Gene3D G3DSA:3.40.50.300 1 279 9.9E-13 T 28-03-2018 SMD44_RS39475 c76ee6326243fb80a02808a77db2ecc3 147 SMART SM00347 27 128 9.9E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS39475 c76ee6326243fb80a02808a77db2ecc3 147 Gene3D G3DSA:1.10.10.10 1 141 1.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39475 c76ee6326243fb80a02808a77db2ecc3 147 Pfam PF12802 MarR family 33 91 9.0E-12 T 28-03-2018 SMD44_RS39475 c76ee6326243fb80a02808a77db2ecc3 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 3.1E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS39475 c76ee6326243fb80a02808a77db2ecc3 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.1E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS39475 c76ee6326243fb80a02808a77db2ecc3 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.1E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS39475 c76ee6326243fb80a02808a77db2ecc3 147 SUPERFAMILY SSF46785 7 140 1.88E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05700 54dd629b3a1e5474c2e8105d0aea01fd 106 SUPERFAMILY SSF54909 1 97 1.38E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS05700 54dd629b3a1e5474c2e8105d0aea01fd 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 80 8.6E-9 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD44_RS05700 54dd629b3a1e5474c2e8105d0aea01fd 106 Gene3D G3DSA:3.30.70.100 1 106 3.5E-16 T 28-03-2018 SMD44_RS21840 8d3d6b917006ab99f87541f1aaeabbb0 440 SUPERFAMILY SSF103473 15 426 1.16E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS21840 8d3d6b917006ab99f87541f1aaeabbb0 440 Gene3D G3DSA:1.20.1250.20 221 431 6.8E-15 T 28-03-2018 SMD44_RS21840 8d3d6b917006ab99f87541f1aaeabbb0 440 Gene3D G3DSA:1.20.1250.20 19 209 6.7E-27 T 28-03-2018 SMD44_RS21840 8d3d6b917006ab99f87541f1aaeabbb0 440 Pfam PF07690 Major Facilitator Superfamily 32 268 1.4E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 SUPERFAMILY SSF103473 20 208 4.97E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 SUPERFAMILY SSF103473 262 434 4.97E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 SUPERFAMILY SSF103473 480 506 4.97E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 28 502 2.9E-82 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 Gene3D G3DSA:1.20.1250.20 25 215 2.4E-38 T 28-03-2018 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 Pfam PF07690 Major Facilitator Superfamily 33 424 2.5E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 31 55 4.6E-12 T 28-03-2018 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 4.6E-12 T 28-03-2018 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 415 434 4.6E-12 T 28-03-2018 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 121 141 4.6E-12 T 28-03-2018 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 216 234 4.6E-12 T 28-03-2018 SMD44_RS23910 628fc0f7ace552d3b7debdc2a99e6460 539 Gene3D G3DSA:1.20.1250.20 266 517 4.6E-34 T 28-03-2018 SMD44_RS08850 d746ba7138679e82cfeb4c80c25c0107 342 Gene3D G3DSA:1.20.1250.20 11 240 5.2E-4 T 28-03-2018 SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 211 4.3E-42 T 28-03-2018 SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 31 42 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 106 125 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 94 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 Gene3D G3DSA:3.40.50.720 2 215 9.8E-49 T 28-03-2018 SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 SUPERFAMILY SSF51735 4 212 1.93E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 144 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 96 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 31 42 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 106 125 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20345 3c567c8b49b8c58020b62bcdf7e13cc5 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 196 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SUPERFAMILY SSF58104 99 285 3.66E-8 T 28-03-2018 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SUPERFAMILY SSF58104 288 469 2.49E-12 T 28-03-2018 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SUPERFAMILY SSF58104 564 687 2.62E-9 T 28-03-2018 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00065 709 871 0.0034 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1139 1152 1.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1080 1094 1.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1098 1108 1.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1115 1133 1.4E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1034 1153 3.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:1.10.287.130 917 982 5.1E-16 T 28-03-2018 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SUPERFAMILY SSF55874 975 1156 4.85E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:3.30.565.10 990 1163 1.4E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00387 1033 1155 6.7E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Pfam PF13185 GAF domain 708 861 9.0E-17 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Pfam PF00672 HAMP domain 550 591 3.1E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SUPERFAMILY SSF52172 1213 1334 1.29E-37 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00448 1215 1329 4.1E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:3.40.50.2300 1212 1367 1.1E-36 T 28-03-2018 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Pfam PF00072 Response regulator receiver domain 1217 1329 1.3E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 919 986 3.2E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:2.60.120.260 188 279 5.1E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:2.60.120.260 372 463 8.9E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:2.60.120.260 556 648 1.4E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:2.60.120.260 88 187 4.3E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:2.60.120.260 7 87 0.23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:2.60.120.260 280 371 1.8E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:2.60.120.260 464 555 1.1E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00388 918 986 8.7E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SUPERFAMILY SSF55781 682 862 3.05E-20 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00304 176 228 1.3E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00304 544 596 1.7E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00304 452 504 9.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00304 360 412 9.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00304 636 688 6.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00304 79 136 2.3E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SMART SM00304 268 320 4.9E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 SUPERFAMILY SSF47384 905 987 6.28E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS13825 2d6ecaa6078dc435bb3e14981a4285bc 1409 Gene3D G3DSA:3.30.450.40 679 916 9.5E-26 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS16460 7e76bcdeef24c22da42238b3e9296909 475 SUPERFAMILY SSF55846 280 468 3.6E-49 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS16460 7e76bcdeef24c22da42238b3e9296909 475 Gene3D G3DSA:3.40.80.10 271 475 1.5E-46 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS16460 7e76bcdeef24c22da42238b3e9296909 475 SMART SM00701 280 428 1.5E-58 T 28-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS16460 7e76bcdeef24c22da42238b3e9296909 475 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 303 455 1.5E-17 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS05895 d461f6c420095bee0113ba6f118e0078 241 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 40 127 3.2E-11 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS05895 d461f6c420095bee0113ba6f118e0078 241 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 39 219 2.3E-23 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS05895 d461f6c420095bee0113ba6f118e0078 241 SUPERFAMILY SSF109854 34 157 5.04E-15 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS05895 d461f6c420095bee0113ba6f118e0078 241 Gene3D G3DSA:1.20.120.450 25 217 8.2E-21 T 28-03-2018 SMD44_RS40730 6a0047b6f14552816b5ed2d6082980fd 343 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 51 266 8.4E-12 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMD44_RS40730 6a0047b6f14552816b5ed2d6082980fd 343 SUPERFAMILY SSF51197 40 333 4.12E-56 T 28-03-2018 SMD44_RS40730 6a0047b6f14552816b5ed2d6082980fd 343 Gene3D G3DSA:2.60.120.330 181 335 2.2E-26 T 28-03-2018 IPR027443 Isopenicillin N synthase-like SMD44_RS40730 6a0047b6f14552816b5ed2d6082980fd 343 Gene3D G3DSA:2.60.120.330 5 179 7.3E-21 T 28-03-2018 IPR027443 Isopenicillin N synthase-like SMD44_RS03120 d8c99028ef5c024eff850f01856d0ff0 364 PIRSF PIRSF026760 10 354 9.7E-75 T 28-03-2018 IPR011669 Uncharacterised conserved protein UCP026760 SMD44_RS03120 d8c99028ef5c024eff850f01856d0ff0 364 Gene3D G3DSA:3.40.50.300 145 336 5.0E-28 T 28-03-2018 SMD44_RS03120 d8c99028ef5c024eff850f01856d0ff0 364 Gene3D G3DSA:3.40.50.720 10 142 2.1E-30 T 28-03-2018 SMD44_RS03120 d8c99028ef5c024eff850f01856d0ff0 364 Pfam PF07755 Domain of unknown function (DUF1611_C) P-loop domain 153 345 9.7E-55 T 28-03-2018 IPR035086 Domain of unknown function DUF1611, P-loop SMD44_RS03120 d8c99028ef5c024eff850f01856d0ff0 364 SUPERFAMILY SSF52540 10 349 2.47E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS03120 d8c99028ef5c024eff850f01856d0ff0 364 Pfam PF17396 Domain of unknown function (DUF1611_N) Rossmann-like domain 48 139 1.1E-18 T 28-03-2018 IPR035402 Domain of unknown function DUF1611_N, Rossmann-like domain SMD44_RS02905 988d898840f713c85ae44c6885819a91 216 SUPERFAMILY SSF160904 20 196 2.22E-28 T 28-03-2018 SMD44_RS02905 988d898840f713c85ae44c6885819a91 216 Gene3D G3DSA:1.10.3300.10 13 200 3.7E-28 T 28-03-2018 IPR023286 ABATE domain SMD44_RS02905 988d898840f713c85ae44c6885819a91 216 Pfam PF11706 CGNR zinc finger 159 196 8.1E-8 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS06975 e324e1537873eac6f1774940786bff7c 200 Gene3D G3DSA:3.40.50.300 10 171 2.3E-14 T 28-03-2018 SMD44_RS06975 e324e1537873eac6f1774940786bff7c 200 SUPERFAMILY SSF52540 4 153 5.88E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS06330 428e2c00e70b1ffce8af41a2455c9d67 434 SUPERFAMILY SSF103473 13 399 1.26E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS06330 428e2c00e70b1ffce8af41a2455c9d67 434 Pfam PF05977 Transmembrane secretion effector 19 339 2.1E-24 T 28-03-2018 IPR010290 Transmembrane secretion effector SMD44_RS06330 428e2c00e70b1ffce8af41a2455c9d67 434 Gene3D G3DSA:1.20.1250.20 10 199 6.4E-18 T 28-03-2018 SMD44_RS06330 428e2c00e70b1ffce8af41a2455c9d67 434 Gene3D G3DSA:1.20.1250.20 221 412 1.5E-9 T 28-03-2018 SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 SUPERFAMILY SSF64288 63 236 1.88E-29 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 6.7E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 6.7E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 SMART SM00345 17 75 5.1E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 Gene3D G3DSA:3.40.1410.10 99 237 8.0E-40 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 Gene3D G3DSA:1.10.10.10 5 77 2.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 SMART SM00866 94 233 1.3E-15 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 75 2.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 Pfam PF07702 UTRA domain 104 231 2.4E-18 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS06035 1d6ad074c33220c3f006d606c137a188 253 SUPERFAMILY SSF46785 12 84 8.62E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10270 36685da97b04e9c557645a09f18df266 122 Pfam PF05899 Protein of unknown function (DUF861) 45 116 6.1E-18 T 28-03-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 SMD44_RS10270 36685da97b04e9c557645a09f18df266 122 SUPERFAMILY SSF51182 20 118 7.8E-14 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS10270 36685da97b04e9c557645a09f18df266 122 Gene3D G3DSA:2.60.120.10 3 119 5.1E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 10 420 1.6E-202 T 28-03-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 PIRSF PIRSF000521 189 422 1.9E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 PIRSF PIRSF000521 128 166 0.11 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 PIRSF PIRSF000521 9 135 2.1E-5 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 SUPERFAMILY SSF53383 12 420 6.4E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 Gene3D G3DSA:3.90.1150.10 4 166 2.0E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 Gene3D G3DSA:3.90.1150.10 310 423 3.0E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 Pfam PF00202 Aminotransferase class-III 27 419 8.1E-78 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 Gene3D G3DSA:3.40.640.10 182 309 1.2E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS09700 7f99f0eb6bd294bcf76a67b7870efbd5 423 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 6 422 6.0E-140 T 28-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 79 84 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 Pfam PF00089 Trypsin 36 269 1.2E-52 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 Gene3D G3DSA:2.40.10.10 141 274 1.4E-38 T 28-03-2018 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 SUPERFAMILY SSF50494 9 268 9.18E-60 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 Gene3D G3DSA:2.40.10.10 36 73 1.9E-13 T 28-03-2018 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 Gene3D G3DSA:2.40.10.10 74 140 2.2E-14 T 28-03-2018 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 227 238 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 226 238 4.6E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 132 146 4.6E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 69 84 4.6E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS31535 3a6e0180f4460bd1d04dc17c62fe7587 276 SMART SM00020 35 272 5.8E-60 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 997 1011 - T 28-03-2018 IPR019775 WD40 repeat, conserved site SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:3.30.460.10 1280 1448 1.1E-50 T 28-03-2018 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF04229 GrpB protein 1278 1441 4.0E-48 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SUPERFAMILY SSF81301 1279 1444 1.99E-43 T 28-03-2018 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SUPERFAMILY SSF52540 115 324 5.0E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 PRINTS PR00320 G protein beta WD-40 repeat signature 704 718 4.8E-7 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 PRINTS PR00320 G protein beta WD-40 repeat signature 997 1011 4.8E-7 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 PRINTS PR00320 G protein beta WD-40 repeat signature 620 634 4.8E-7 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:2.130.10.10 710 771 3.9E-26 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 598 633 9.0E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 859 884 0.014 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 806 842 4.4E-9 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 681 717 5.7E-9 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 986 1010 4.9E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 765 801 6.4E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 1070 1093 7.7E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 726 759 8.3E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 639 675 1.2E-9 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Pfam PF00400 WD domain, G-beta repeat 1099 1135 9.1E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:2.130.10.10 916 1080 7.0E-38 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00530 21 77 2.9E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 704 718 - T 28-03-2018 IPR019775 WD40 repeat, conserved site SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SUPERFAMILY SSF50978 941 1169 1.01E-64 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SUPERFAMILY SSF50978 857 898 1.01E-64 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:2.130.10.10 847 915 2.7E-16 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:2.130.10.10 1081 1279 3.7E-33 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SUPERFAMILY SSF50978 600 928 9.16E-96 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 762 801 9.3E-10 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 594 633 2.1E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 846 884 1.7E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 1096 1135 3.9E-11 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 636 675 7.4E-14 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 1054 1093 1.2E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 933 968 0.54 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 971 1010 5.7E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 804 843 2.2E-12 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 720 759 1.7E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 1016 1051 1.3 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 SMART SM00320 678 717 4.9E-12 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:2.40.50.140 637 672 1.9E-21 T 28-03-2018 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 662 676 - T 28-03-2018 IPR019775 WD40 repeat, conserved site SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:1.10.10.670 798 846 5.1E-23 T 28-03-2018 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:1.10.10.670 673 709 8.9E-21 T 28-03-2018 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:2.40.10.120 772 797 2.0E-14 T 28-03-2018 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:2.80.10.50 596 636 2.3E-16 T 28-03-2018 SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 620 634 - T 28-03-2018 IPR019775 WD40 repeat, conserved site SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 788 802 - T 28-03-2018 IPR019775 WD40 repeat, conserved site SMD44_RS02525 a355f8793af3e7c1e2e71db2e99fc060 1458 Gene3D G3DSA:3.40.50.300 105 568 4.0E-7 T 28-03-2018 SMD44_RS12715 9cf16c1f4acbcbd2bbf4526bb815d40c 269 Gene3D G3DSA:1.20.5.110 169 205 4.6E-12 T 28-03-2018 SMD44_RS12715 9cf16c1f4acbcbd2bbf4526bb815d40c 269 Pfam PF07885 Ion channel 128 204 9.2E-17 T 28-03-2018 IPR013099 Potassium channel domain SMD44_RS12715 9cf16c1f4acbcbd2bbf4526bb815d40c 269 Gene3D G3DSA:1.10.287.70 15 91 0.0017 T 28-03-2018 SMD44_RS12715 9cf16c1f4acbcbd2bbf4526bb815d40c 269 Gene3D G3DSA:1.10.287.70 110 167 8.1E-14 T 28-03-2018 SMD44_RS12715 9cf16c1f4acbcbd2bbf4526bb815d40c 269 SUPERFAMILY SSF81324 22 204 9.22E-38 T 28-03-2018 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 SUPERFAMILY SSF48179 202 295 1.09E-19 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 5 32 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 SMART SM00984 316 411 7.7E-18 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 SUPERFAMILY SSF51735 6 196 8.75E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 Gene3D G3DSA:3.40.50.720 226 417 1.6E-43 T 28-03-2018 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 408 1.3E-13 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 PIRSF PIRSF500136 1 417 1.8E-119 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 SUPERFAMILY SSF52413 303 410 3.53E-20 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 184 3.7E-22 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 PIRSF PIRSF000124 3 416 9.9E-39 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 406 1.4E-92 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 269 3.3E-17 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 Gene3D G3DSA:1.20.5.170 203 225 3.0E-7 T 28-03-2018 SMD44_RS25830 5eef7f69f6d75014f06719c2f50adbb8 417 Gene3D G3DSA:3.40.50.720 1 202 2.1E-32 T 28-03-2018 SMD44_RS02055 a8bfbaa5b4d3f83ad1893675ecf8e38e 295 SUPERFAMILY SSF161098 23 295 3.92E-72 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02055 a8bfbaa5b4d3f83ad1893675ecf8e38e 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 288 3.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02055 a8bfbaa5b4d3f83ad1893675ecf8e38e 295 Gene3D G3DSA:1.10.3720.10 18 282 5.9E-41 T 28-03-2018 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 PIRSF PIRSF001134 1 361 1.2E-135 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 Gene3D G3DSA:2.40.10.10 259 348 9.8E-22 T 28-03-2018 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 Gene3D G3DSA:2.40.10.10 174 258 6.6E-22 T 28-03-2018 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 Gene3D G3DSA:3.30.300.50 99 168 2.4E-19 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 Gene3D G3DSA:3.30.300.50 41 98 1.3E-18 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 Pfam PF00089 Trypsin 201 352 4.3E-9 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 Pfam PF02983 Alpha-lytic protease prodomain 102 156 3.2E-14 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 SUPERFAMILY SSF50494 180 354 1.16E-38 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 261 281 5.7E-46 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 326 340 5.7E-46 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 200 214 5.7E-46 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 282 299 5.7E-46 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 302 325 5.7E-46 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08900 23fef228b7eff2b1c0d634206f1871e5 361 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 311 322 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS37465 d94d5400f45d1fe9011d1f7b68f1d8ce 411 Pfam PF01547 Bacterial extracellular solute-binding protein 36 325 1.8E-40 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS37465 d94d5400f45d1fe9011d1f7b68f1d8ce 411 SUPERFAMILY SSF53850 24 395 2.72E-64 T 28-03-2018 SMD44_RS37465 d94d5400f45d1fe9011d1f7b68f1d8ce 411 Gene3D G3DSA:3.40.190.10 22 152 3.7E-27 T 28-03-2018 SMD44_RS37465 d94d5400f45d1fe9011d1f7b68f1d8ce 411 Gene3D G3DSA:3.40.190.10 153 409 2.1E-34 T 28-03-2018 SMD44_RS04140 987a4973f169dd871484c7f215aebca1 451 SUPERFAMILY SSF53187 361 450 1.06E-53 T 28-03-2018 SMD44_RS04140 987a4973f169dd871484c7f215aebca1 451 SUPERFAMILY SSF53187 6 199 1.06E-53 T 28-03-2018 SMD44_RS04140 987a4973f169dd871484c7f215aebca1 451 Gene3D G3DSA:3.30.70.360 203 357 1.3E-36 T 28-03-2018 SMD44_RS04140 987a4973f169dd871484c7f215aebca1 451 Pfam PF07687 Peptidase dimerisation domain 204 347 3.4E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS04140 987a4973f169dd871484c7f215aebca1 451 Gene3D G3DSA:3.40.630.10 6 202 1.4E-37 T 28-03-2018 SMD44_RS04140 987a4973f169dd871484c7f215aebca1 451 Pfam PF01546 Peptidase family M20/M25/M40 86 438 8.6E-35 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS16235 5c03849d29dea638b4248975927a2a22 1675 SUPERFAMILY SSF51735 1010 1112 6.43E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS16235 5c03849d29dea638b4248975927a2a22 1675 SUPERFAMILY SSF51735 1150 1351 6.43E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS16235 5c03849d29dea638b4248975927a2a22 1675 Gene3D G3DSA:3.40.50.720 1003 1353 5.4E-53 T 28-03-2018 SMD44_RS16235 5c03849d29dea638b4248975927a2a22 1675 SUPERFAMILY SSF53223 819 1005 7.19E-23 T 28-03-2018 SMD44_RS16235 5c03849d29dea638b4248975927a2a22 1675 PIRSF PIRSF036761 52 1675 0.0 T 28-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 SMD44_RS16235 5c03849d29dea638b4248975927a2a22 1675 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 117 1668 0.0 T 28-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 324 344 2.1E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 381 392 2.1E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 448 464 2.1E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 360 376 2.1E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 Gene3D G3DSA:3.10.170.10 220 372 3.0E-46 T 28-03-2018 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 Gene3D G3DSA:1.10.390.10 374 547 1.2E-49 T 28-03-2018 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 83 130 1.7E-18 T 28-03-2018 IPR011096 FTP domain SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 SUPERFAMILY SSF55486 221 546 2.93E-79 T 28-03-2018 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 224 369 1.3E-45 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMD44_RS29485 85daaf7a30d29ed12217fda701bdb559 547 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 373 546 9.0E-55 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD44_RS39060 eb9826b0bd67efb0e88d6696e86f145b 166 Pfam PF01750 Hydrogenase maturation protease 52 152 7.6E-9 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 SMD44_RS39060 eb9826b0bd67efb0e88d6696e86f145b 166 Gene3D G3DSA:3.40.50.1450 3 165 7.5E-37 T 28-03-2018 IPR023430 Peptidase HybD-like domain SMD44_RS39060 eb9826b0bd67efb0e88d6696e86f145b 166 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 9 153 8.7E-32 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 SMD44_RS39060 eb9826b0bd67efb0e88d6696e86f145b 166 SUPERFAMILY SSF53163 7 153 3.4E-31 T 28-03-2018 IPR023430 Peptidase HybD-like domain SMD44_RS32745 8c51b1a95f156a116ffe952125ed983a 163 Gene3D G3DSA:1.10.10.10 6 153 2.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32745 8c51b1a95f156a116ffe952125ed983a 163 Pfam PF01047 MarR family 50 106 1.6E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS32745 8c51b1a95f156a116ffe952125ed983a 163 SMART SM00347 43 143 4.0E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS32745 8c51b1a95f156a116ffe952125ed983a 163 SUPERFAMILY SSF46785 33 155 3.81E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19245 d1134c2704682bc1ceb5400162eb83bc 321 SUPERFAMILY SSF103025 22 240 3.61E-53 T 28-03-2018 SMD44_RS19245 d1134c2704682bc1ceb5400162eb83bc 321 Pfam PF01571 Aminomethyltransferase folate-binding domain 22 141 1.3E-18 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal SMD44_RS19245 d1134c2704682bc1ceb5400162eb83bc 321 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 224 303 7.6E-7 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD44_RS19245 d1134c2704682bc1ceb5400162eb83bc 321 PIRSF PIRSF006487 169 319 8.9E-9 T 28-03-2018 SMD44_RS19245 d1134c2704682bc1ceb5400162eb83bc 321 PIRSF PIRSF006487 13 147 2.2E-10 T 28-03-2018 SMD44_RS19245 d1134c2704682bc1ceb5400162eb83bc 321 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 187 250 5.3E-20 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site SMD44_RS19245 d1134c2704682bc1ceb5400162eb83bc 321 Gene3D G3DSA:3.30.70.1400 47 237 1.7E-30 T 28-03-2018 SMD44_RS19245 d1134c2704682bc1ceb5400162eb83bc 321 Gene3D G3DSA:2.40.30.110 239 318 3.1E-10 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD44_RS30050 18c94b8738defeaea63707859969ae0d 340 Gene3D G3DSA:3.75.10.10 1 340 3.3E-117 T 28-03-2018 SMD44_RS30050 18c94b8738defeaea63707859969ae0d 340 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 4 338 4.3E-106 T 28-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 SMD44_RS30050 18c94b8738defeaea63707859969ae0d 340 Hamap MF_01841 Agmatine deiminase [aguA]. 1 339 46.366 T 28-03-2018 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 SMD44_RS30050 18c94b8738defeaea63707859969ae0d 340 SUPERFAMILY SSF55909 1 339 5.53E-117 T 28-03-2018 SMD44_RS25370 526bf0ad1ef6600203a4be16617c5608 142 Pfam PF01575 MaoC like domain 14 108 1.2E-25 T 28-03-2018 IPR002539 MaoC-like domain SMD44_RS25370 526bf0ad1ef6600203a4be16617c5608 142 SUPERFAMILY SSF54637 4 136 7.46E-28 T 28-03-2018 IPR029069 HotDog domain SMD44_RS25370 526bf0ad1ef6600203a4be16617c5608 142 PRINTS PR01483 Fatty acid synthase signature 25 47 1.1E-7 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 SMD44_RS25370 526bf0ad1ef6600203a4be16617c5608 142 PRINTS PR01483 Fatty acid synthase signature 47 68 1.1E-7 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 SMD44_RS25370 526bf0ad1ef6600203a4be16617c5608 142 Gene3D G3DSA:3.10.129.10 2 142 1.8E-35 T 28-03-2018 SMD44_RS32825 01ef7a53f1dcccc792112ecaeac3e64d 302 Gene3D G3DSA:3.40.50.620 6 268 6.6E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS32825 01ef7a53f1dcccc792112ecaeac3e64d 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 11 302 4.0E-137 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD44_RS32825 01ef7a53f1dcccc792112ecaeac3e64d 302 SUPERFAMILY SSF52402 7 210 4.42E-62 T 28-03-2018 SMD44_RS32825 01ef7a53f1dcccc792112ecaeac3e64d 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 32 256 3.5E-48 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMD44_RS32825 01ef7a53f1dcccc792112ecaeac3e64d 302 PIRSF PIRSF002936 2 302 7.6E-136 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 253 2.5E-58 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 SMART SM00825 Beta-ketoacyl synthase 8 411 7.0E-13 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 Gene3D G3DSA:3.40.47.10 1 264 1.6E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 SUPERFAMILY SSF53901 220 419 1.57E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 6 418 5.8E-156 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 PIRSF PIRSF000447 3 420 4.3E-148 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 SUPERFAMILY SSF53901 6 258 5.26E-71 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 Gene3D G3DSA:3.40.47.10 269 420 2.3E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12780 14a49249a237a1c298af7a76d8a3d8ff 420 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 1.0E-33 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 Pfam PF01327 Polypeptide deformylase 14 162 6.6E-41 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 20 167 4.0E-35 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 PRINTS PR01576 Peptide deformylase signature 43 72 6.2E-29 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 PRINTS PR01576 Peptide deformylase signature 114 132 6.2E-29 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 PRINTS PR01576 Peptide deformylase signature 102 113 6.2E-29 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 PRINTS PR01576 Peptide deformylase signature 133 162 6.2E-29 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 PIRSF PIRSF004749 5 185 3.5E-41 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 Hamap MF_00163 Peptide deformylase [def]. 12 175 26.928 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 Gene3D G3DSA:3.90.45.10 5 186 5.9E-56 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS05590 f7ef88d9ce3bfe4776ec4c46264cf885 188 SUPERFAMILY SSF56420 13 172 2.49E-52 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28835 b8f0e50e5fddd3177ea3b958021b6b61 281 SUPERFAMILY SSF53335 17 250 1.91E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS28835 b8f0e50e5fddd3177ea3b958021b6b61 281 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 274 8.5E-71 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SMD44_RS28835 b8f0e50e5fddd3177ea3b958021b6b61 281 Pfam PF05175 Methyltransferase small domain 114 187 3.1E-12 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMD44_RS28835 b8f0e50e5fddd3177ea3b958021b6b61 281 Gene3D G3DSA:3.40.50.150 79 281 2.4E-44 T 28-03-2018 SMD44_RS28835 b8f0e50e5fddd3177ea3b958021b6b61 281 Gene3D G3DSA:1.10.8.10 5 78 2.8E-16 T 28-03-2018 SMD44_RS28835 b8f0e50e5fddd3177ea3b958021b6b61 281 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 181 187 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD44_RS28835 b8f0e50e5fddd3177ea3b958021b6b61 281 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 17 278 6.5E-49 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SMD44_RS28835 b8f0e50e5fddd3177ea3b958021b6b61 281 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 278 41.728 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 Hamap MF_00163 Peptide deformylase [def]. 40 206 27.868 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 PRINTS PR01576 Peptide deformylase signature 164 193 5.8E-32 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 PRINTS PR01576 Peptide deformylase signature 133 144 5.8E-32 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 PRINTS PR01576 Peptide deformylase signature 145 163 5.8E-32 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 PRINTS PR01576 Peptide deformylase signature 71 100 5.8E-32 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 SUPERFAMILY SSF56420 39 203 7.2E-53 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 Gene3D G3DSA:3.90.45.10 24 211 1.4E-58 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 Pfam PF01327 Polypeptide deformylase 42 196 8.1E-45 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 PIRSF PIRSF004749 16 214 2.8E-45 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28290 9bbc69b72dcfaaa966de1b28b9835c23 216 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 47 203 1.3E-39 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 Pfam PF07731 Multicopper oxidase 379 493 8.0E-22 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 SUPERFAMILY SSF49503 196 312 7.72E-21 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 Pfam PF00394 Multicopper oxidase 252 309 5.5E-5 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 ProSitePatterns PS00080 Multicopper oxidases signature 2. 474 485 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 SUPERFAMILY SSF49503 61 190 1.16E-35 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 Gene3D G3DSA:2.60.40.420 48 193 1.3E-33 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 SUPERFAMILY SSF49503 383 491 5.2E-27 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 Gene3D G3DSA:2.60.40.420 194 351 4.8E-19 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 Gene3D G3DSA:2.60.40.420 352 492 4.3E-29 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS25785 4a0f708edac320bc4a263dec85e2bc87 508 Pfam PF07732 Multicopper oxidase 77 190 1.1E-30 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD44_RS17755 0d90fff9b1b24a5d6d6dfd537eaec8b6 361 Pfam PF12840 Helix-turn-helix domain 280 337 8.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17755 0d90fff9b1b24a5d6d6dfd537eaec8b6 361 Gene3D G3DSA:1.10.10.10 111 211 0.024 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17755 0d90fff9b1b24a5d6d6dfd537eaec8b6 361 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 281 296 1.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS17755 0d90fff9b1b24a5d6d6dfd537eaec8b6 361 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 328 343 1.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS17755 0d90fff9b1b24a5d6d6dfd537eaec8b6 361 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 313 328 1.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS17755 0d90fff9b1b24a5d6d6dfd537eaec8b6 361 SMART SM00418 279 357 2.0E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS17755 0d90fff9b1b24a5d6d6dfd537eaec8b6 361 Gene3D G3DSA:1.10.10.10 270 361 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17755 0d90fff9b1b24a5d6d6dfd537eaec8b6 361 SUPERFAMILY SSF46785 271 353 1.98E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35180 cb260f638a684754b1e75f2e80277a9b 186 Gene3D G3DSA:2.60.130.10 2 185 8.5E-46 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD44_RS35180 cb260f638a684754b1e75f2e80277a9b 186 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 8 184 5.2E-42 T 28-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 SMD44_RS35180 cb260f638a684754b1e75f2e80277a9b 186 SUPERFAMILY SSF49482 4 184 3.92E-36 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 Gene3D G3DSA:3.30.160.20 211 318 3.3E-32 T 28-03-2018 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 Pfam PF00472 RF-1 domain 214 323 1.7E-39 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 SUPERFAMILY SSF75620 8 355 8.37E-127 T 28-03-2018 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 356 1.7E-149 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 SMART SM00937 63 181 4.5E-53 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 Gene3D G3DSA:1.20.58.410 3 92 3.0E-21 T 28-03-2018 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 Pfam PF03462 PCRF domain 11 206 4.8E-67 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 SMD44_RS28830 61b3100939a94bb4db60746d74bf509e 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 358 37.564 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SMD44_RS15090 a7a3328319dd69b6d8bd7f7db390552c 286 SUPERFAMILY SSF53335 17 241 5.11E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS15090 a7a3328319dd69b6d8bd7f7db390552c 286 Gene3D G3DSA:3.40.50.150 10 277 1.9E-40 T 28-03-2018 SMD44_RS15090 a7a3328319dd69b6d8bd7f7db390552c 286 Pfam PF01564 Spermine/spermidine synthase domain 57 182 2.2E-5 T 28-03-2018 SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 Pfam PF00271 Helicase conserved C-terminal domain 335 446 9.5E-12 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 SMART SM00487 96 305 1.4E-31 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 SMART SM00490 365 446 1.6E-17 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 Gene3D G3DSA:3.40.50.300 322 481 1.7E-20 T 28-03-2018 SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 Pfam PF00270 DEAD/DEAH box helicase 102 277 1.1E-24 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 Gene3D G3DSA:3.40.50.300 73 300 9.6E-34 T 28-03-2018 SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 SUPERFAMILY SSF52540 328 463 8.48E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 SUPERFAMILY SSF52540 149 291 8.48E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 64 813 0.0 T 28-03-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria SMD44_RS23295 ae89df101522be7540e62a61f371afed 817 Pfam PF09369 Domain of unknown function (DUF1998) 707 786 3.8E-20 T 28-03-2018 IPR018973 DEAD/DEAH-box helicase, putative SMD44_RS25205 1181d6a3f382835fe7d81318565ebffb 518 Gene3D G3DSA:1.20.1250.20 1 191 5.3E-28 T 28-03-2018 SMD44_RS25205 1181d6a3f382835fe7d81318565ebffb 518 Pfam PF07690 Major Facilitator Superfamily 14 407 2.5E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS25205 1181d6a3f382835fe7d81318565ebffb 518 SUPERFAMILY SSF103473 246 463 4.05E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS25205 1181d6a3f382835fe7d81318565ebffb 518 SUPERFAMILY SSF103473 4 189 4.05E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS25205 1181d6a3f382835fe7d81318565ebffb 518 Gene3D G3DSA:1.20.1250.20 257 469 3.9E-22 T 28-03-2018 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 34.093 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 374 1.4E-139 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 Pfam PF01264 Chorismate synthase 4 368 1.1E-116 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 PIRSF PIRSF001456 1 387 3.2E-126 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 SUPERFAMILY SSF103263 3 391 6.54E-137 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 Gene3D G3DSA:3.60.150.10 3 394 7.1E-140 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS07325 7e3e658a7574c5f6a1fd921b348f408d 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 Gene3D G3DSA:3.50.50.60 405 482 6.2E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 SUPERFAMILY SSF51971 144 400 1.88E-67 T 28-03-2018 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 5.8E-25 T 28-03-2018 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 5.8E-25 T 28-03-2018 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 5.8E-25 T 28-03-2018 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 5.8E-25 T 28-03-2018 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 474 3.1E-208 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 Gene3D G3DSA:3.40.50.720 145 241 9.8E-23 T 28-03-2018 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 456 1.2E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 SUPERFAMILY SSF46548 10 155 7.85E-34 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 Gene3D G3DSA:3.50.50.60 242 327 2.7E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 40 131 2.4E-20 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 SMD44_RS10705 842b5f9e76012f94785ae8626aab2e92 486 Gene3D G3DSA:1.10.1060.10 6 144 5.6E-37 T 28-03-2018 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Pfam PF00582 Universal stress protein family 240 355 1.8E-8 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 SMART SM00388 609 677 1.2E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Gene3D G3DSA:3.40.50.620 236 371 5.3E-14 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Pfam PF00512 His Kinase A (phospho-acceptor) domain 610 677 1.2E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 SUPERFAMILY SSF52402 241 347 3.17E-10 T 28-03-2018 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 SUPERFAMILY SSF55874 666 826 3.67E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 7 220 1.7E-88 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 PRINTS PR00344 Bacterial sensor protein C-terminal signature 788 806 9.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 PRINTS PR00344 Bacterial sensor protein C-terminal signature 773 783 9.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 PRINTS PR00344 Bacterial sensor protein C-terminal signature 812 825 9.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 PRINTS PR00344 Bacterial sensor protein C-terminal signature 755 769 9.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Gene3D G3DSA:3.40.50.300 5 149 7.9E-18 T 28-03-2018 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Gene3D G3DSA:1.20.120.620 391 492 6.8E-20 T 28-03-2018 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Gene3D G3DSA:1.10.287.130 600 663 4.7E-14 T 28-03-2018 SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 719 826 8.1E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Pfam PF13493 Domain of unknown function (DUF4118) 396 499 1.1E-19 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 SMART SM00387 718 828 1.0E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 Gene3D G3DSA:3.30.565.10 664 828 1.8E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05410 ff42ab97d135df56052d9b9766d94f78 847 SUPERFAMILY SSF47384 600 677 6.08E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS17760 35c8a12dfaac56f687dc047e3df32ed7 576 Pfam PF00239 Resolvase, N terminal domain 22 175 6.6E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS17760 35c8a12dfaac56f687dc047e3df32ed7 576 SUPERFAMILY SSF53041 23 175 4.45E-13 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS17760 35c8a12dfaac56f687dc047e3df32ed7 576 SMART SM00857 18 179 1.5E-7 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS17760 35c8a12dfaac56f687dc047e3df32ed7 576 Pfam PF07508 Recombinase 212 327 5.5E-18 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 SMD44_RS17760 35c8a12dfaac56f687dc047e3df32ed7 576 Gene3D G3DSA:3.40.50.1390 12 189 1.8E-19 T 28-03-2018 SMD44_RS10780 1e2a8a9c97155b510144a988a1d9d9c9 269 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 34 253 30.04 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMD44_RS10780 1e2a8a9c97155b510144a988a1d9d9c9 269 SUPERFAMILY SSF51366 12 257 4.24E-78 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD44_RS10780 1e2a8a9c97155b510144a988a1d9d9c9 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 SMD44_RS10780 1e2a8a9c97155b510144a988a1d9d9c9 269 Gene3D G3DSA:3.20.20.70 1 264 9.5E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS10780 1e2a8a9c97155b510144a988a1d9d9c9 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 254 8.9E-80 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMD44_RS10780 1e2a8a9c97155b510144a988a1d9d9c9 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 33.975 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMD44_RS33595 af52bb265daefbcc3d72c486abfc7b8d 160 Gene3D G3DSA:3.10.129.10 27 160 3.8E-25 T 28-03-2018 SMD44_RS33595 af52bb265daefbcc3d72c486abfc7b8d 160 Pfam PF03061 Thioesterase superfamily 70 138 6.3E-11 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMD44_RS33595 af52bb265daefbcc3d72c486abfc7b8d 160 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 46 155 2.3E-15 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 SMD44_RS33595 af52bb265daefbcc3d72c486abfc7b8d 160 SUPERFAMILY SSF54637 31 154 5.05E-26 T 28-03-2018 IPR029069 HotDog domain SMD44_RS19180 1a0100f076bfc4158090e6f17bf7b404 267 SUPERFAMILY SSF48498 108 259 5.34E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS19180 1a0100f076bfc4158090e6f17bf7b404 267 SUPERFAMILY SSF46689 35 93 5.34E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS19180 1a0100f076bfc4158090e6f17bf7b404 267 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 88 2.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19180 1a0100f076bfc4158090e6f17bf7b404 267 Gene3D G3DSA:1.10.357.10 106 261 1.6E-37 T 28-03-2018 SMD44_RS19180 1a0100f076bfc4158090e6f17bf7b404 267 Gene3D G3DSA:1.10.10.60 20 95 1.3E-14 T 28-03-2018 SMD44_RS19180 1a0100f076bfc4158090e6f17bf7b404 267 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 256 4.7E-21 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS15590 c170c344334783eaeccc04d6e766d3a5 108 Pfam PF12277 Protein of unknown function (DUF3618) 6 51 9.5E-17 T 28-03-2018 IPR022062 Protein of unknown function DUF3618 SMD44_RS24440 a79ebc7dffa1c5d0bde4830adf0b8e78 240 Gene3D G3DSA:1.10.260.40 67 94 3.1E-14 T 28-03-2018 SMD44_RS24440 a79ebc7dffa1c5d0bde4830adf0b8e78 240 SUPERFAMILY SSF48498 118 228 1.74E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS24440 a79ebc7dffa1c5d0bde4830adf0b8e78 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 91 2.4E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS24440 a79ebc7dffa1c5d0bde4830adf0b8e78 240 Gene3D G3DSA:1.10.10.60 29 66 4.6E-14 T 28-03-2018 SMD44_RS24440 a79ebc7dffa1c5d0bde4830adf0b8e78 240 SUPERFAMILY SSF46689 32 112 3.23E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS24440 a79ebc7dffa1c5d0bde4830adf0b8e78 240 Gene3D G3DSA:1.10.357.10 95 233 6.2E-30 T 28-03-2018 SMD44_RS24440 a79ebc7dffa1c5d0bde4830adf0b8e78 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 58 7.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS24440 a79ebc7dffa1c5d0bde4830adf0b8e78 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 66 89 7.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 7 185 4.5E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 185 7.4E-25 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 Gene3D G3DSA:3.40.50.1000 3 31 0.043 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 1.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 1.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 1.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 1.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 179 1.2E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 SUPERFAMILY SSF56784 6 212 3.75E-41 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS42825 050e7b1361b43c912523d33d2dbbf0b0 224 Gene3D G3DSA:3.40.50.1000 43 217 4.9E-31 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS15400 da69966266c34781d0a4d591d7347652 245 Pfam PF13419 Haloacid dehalogenase-like hydrolase 25 208 1.8E-11 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS15400 da69966266c34781d0a4d591d7347652 245 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 21 240 1.1E-69 T 28-03-2018 IPR022468 Phosphonatase-like hydrolase SMD44_RS15400 da69966266c34781d0a4d591d7347652 245 SUPERFAMILY SSF56784 18 240 3.1E-36 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS15400 da69966266c34781d0a4d591d7347652 245 Gene3D G3DSA:3.40.50.1000 18 245 1.3E-24 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 SMART SM00729 21 223 4.9E-13 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 27 38 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 Pfam PF04055 Radical SAM superfamily 26 187 2.1E-35 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 Pfam PF06463 Molybdenum Cofactor Synthesis C 193 320 5.6E-37 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 SUPERFAMILY SSF102114 13 287 1.22E-73 T 28-03-2018 SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 12 340 41.481 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 Pfam PF13353 4Fe-4S single cluster domain 28 132 2.2E-7 T 28-03-2018 SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 12 340 7.9E-113 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 SMD44_RS09405 e0a35534e15c0caa44612e5eb28d9aa7 340 Gene3D G3DSA:3.20.20.70 8 340 2.0E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 Gene3D G3DSA:3.40.50.300 827 991 2.2E-23 T 28-03-2018 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SMART SM00487 635 825 4.1E-30 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 Gene3D G3DSA:3.40.50.300 352 821 1.5E-36 T 28-03-2018 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SUPERFAMILY SSF52540 817 1025 5.97E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 170 1115 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 Pfam PF00271 Helicase conserved C-terminal domain 845 944 6.8E-14 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SUPERFAMILY SSF141259 504 583 2.09E-18 T 28-03-2018 IPR003711 CarD-like/TRCF domain SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SUPERFAMILY SSF52540 560 818 9.83E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SUPERFAMILY SSF143517 1030 1152 4.97E-32 T 28-03-2018 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SMART SM01058 510 611 8.2E-48 T 28-03-2018 IPR003711 CarD-like/TRCF domain SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 Pfam PF00270 DEAD/DEAH box helicase 642 802 1.7E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SUPERFAMILY SSF52540 400 492 1.38E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SUPERFAMILY SSF52540 17 370 8.32E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 Pfam PF02559 CarD-like/TRCF domain 511 610 4.9E-32 T 28-03-2018 IPR003711 CarD-like/TRCF domain SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SMART SM00982 1043 1141 7.1E-36 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 Pfam PF03461 TRCF domain 1044 1126 4.6E-24 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1136 28.625 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SMD44_RS16870 9821a82a2eab8dd1dfc6e1af689ddc6c 1187 SMART SM00490 861 945 2.6E-15 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS29700 65c8294ea30654d16c90dffafb909f01 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 331 4.6E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS29700 65c8294ea30654d16c90dffafb909f01 333 SUPERFAMILY SSF161098 107 314 2.83E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS29700 65c8294ea30654d16c90dffafb909f01 333 Gene3D G3DSA:1.10.3720.10 3 320 2.5E-38 T 28-03-2018 SMD44_RS19410 c6c7d92d3e11d851b3d9a9e2964da0f4 122 Pfam PF02583 Metal-sensitive transcriptional repressor 37 117 3.6E-30 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SMD44_RS18670 2790220e1b71276a40a05e5c9cf799b1 686 SUPERFAMILY SSF52540 166 245 5.82E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18670 2790220e1b71276a40a05e5c9cf799b1 686 SUPERFAMILY SSF52540 422 666 5.82E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18670 2790220e1b71276a40a05e5c9cf799b1 686 Gene3D G3DSA:3.40.50.300 172 500 2.1E-29 T 28-03-2018 SMD44_RS18670 2790220e1b71276a40a05e5c9cf799b1 686 Pfam PF13538 UvrD-like helicase C-terminal domain 618 661 9.9E-7 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain SMD44_RS18670 2790220e1b71276a40a05e5c9cf799b1 686 Pfam PF13245 AAA domain 179 483 3.5E-8 T 28-03-2018 SMD44_RS18670 2790220e1b71276a40a05e5c9cf799b1 686 Gene3D G3DSA:3.40.50.300 510 679 6.5E-15 T 28-03-2018 SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 SUPERFAMILY SSF50129 1 152 7.15E-35 T 28-03-2018 IPR011032 GroES-like SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 SMART SM00829 10 305 1.1E-31 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 Gene3D G3DSA:3.40.50.720 159 237 3.7E-15 T 28-03-2018 SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 Gene3D G3DSA:3.90.180.10 1 158 1.0E-47 T 28-03-2018 SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 Pfam PF00107 Zinc-binding dehydrogenase 158 241 4.9E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 Gene3D G3DSA:3.90.180.10 238 307 0.053 T 28-03-2018 SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 1.4E-4 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 SUPERFAMILY SSF51735 119 249 4.86E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS08500 a9d6f1176d0c94091ad168e3dc5efb31 315 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 147 168 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS22790 aa2807f13320d8a69bab94a2e6795315 220 Gene3D G3DSA:3.30.1380.10 80 207 1.5E-17 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS22790 aa2807f13320d8a69bab94a2e6795315 220 SUPERFAMILY SSF55166 78 199 6.8E-22 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS22790 aa2807f13320d8a69bab94a2e6795315 220 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 93 194 5.7E-12 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 SMART SM00823 Phosphopantetheine attachment site 44 113 6.3E-12 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 ProSitePatterns PS00012 Phosphopantetheine attachment site. 68 83 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 Gene3D G3DSA:3.40.50.980 739 758 0.0018 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 SUPERFAMILY SSF52777 131 304 3.0E-48 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 SUPERFAMILY SSF47336 37 109 4.45E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 Pfam PF00668 Condensation domain 128 573 3.3E-97 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 Pfam PF00501 AMP-binding enzyme 594 749 2.0E-36 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 Gene3D G3DSA:3.30.559.10 135 321 9.4E-36 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 SUPERFAMILY SSF56801 553 750 1.06E-49 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 SUPERFAMILY SSF52777 318 582 1.67E-66 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 ProSitePatterns PS00455 Putative AMP-binding domain signature. 738 749 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 Pfam PF00550 Phosphopantetheine attachment site 46 109 9.7E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 Gene3D G3DSA:1.10.1200.10 50 134 3.1E-26 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 PRINTS PR01217 Proline rich extensin signature 829 845 2.7E-11 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 PRINTS PR01217 Proline rich extensin signature 761 777 2.7E-11 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 PRINTS PR01217 Proline rich extensin signature 742 754 2.7E-11 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 PRINTS PR01217 Proline rich extensin signature 805 826 2.7E-11 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 PRINTS PR01217 Proline rich extensin signature 847 864 2.7E-11 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 PRINTS PR01217 Proline rich extensin signature 784 796 2.7E-11 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 Gene3D G3DSA:3.30.300.30 1 49 3.4E-11 T 28-03-2018 SMD44_RS38890 7d7082b05c0f33ea2c7ae646abe67f77 906 Gene3D G3DSA:3.40.50.980 586 738 9.0E-43 T 28-03-2018 SMD44_RS15685 58c7660c4ccd0607cc67c9ab9f9ede2c 498 Pfam PF01235 Sodium:alanine symporter family 59 465 1.1E-126 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SMD44_RS15685 58c7660c4ccd0607cc67c9ab9f9ede2c 498 TIGRFAM TIGR00835 agcS: amino acid carrier protein 23 462 3.6E-112 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SMD44_RS15685 58c7660c4ccd0607cc67c9ab9f9ede2c 498 PRINTS PR00175 Sodium/alanine symporter signature 95 117 1.6E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SMD44_RS15685 58c7660c4ccd0607cc67c9ab9f9ede2c 498 PRINTS PR00175 Sodium/alanine symporter signature 231 250 1.6E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SMD44_RS15685 58c7660c4ccd0607cc67c9ab9f9ede2c 498 PRINTS PR00175 Sodium/alanine symporter signature 432 452 1.6E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SMD44_RS15685 58c7660c4ccd0607cc67c9ab9f9ede2c 498 PRINTS PR00175 Sodium/alanine symporter signature 203 221 1.6E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SMD44_RS15685 58c7660c4ccd0607cc67c9ab9f9ede2c 498 PRINTS PR00175 Sodium/alanine symporter signature 371 393 1.6E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SMD44_RS15685 58c7660c4ccd0607cc67c9ab9f9ede2c 498 PRINTS PR00175 Sodium/alanine symporter signature 321 339 1.6E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SMD44_RS37525 0fcbdd948ef9c7e213de8c2d435a52b5 145 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 15 133 17.617 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMD44_RS37525 0fcbdd948ef9c7e213de8c2d435a52b5 145 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 17 127 1.5E-20 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMD44_RS19155 dbb56b418edabc5cdb2a3dcb64cafc7a 303 Gene3D G3DSA:3.40.190.10 92 183 5.7E-13 T 28-03-2018 SMD44_RS19155 dbb56b418edabc5cdb2a3dcb64cafc7a 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.8E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS19155 dbb56b418edabc5cdb2a3dcb64cafc7a 303 SUPERFAMILY SSF46785 1 112 3.22E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19155 dbb56b418edabc5cdb2a3dcb64cafc7a 303 Gene3D G3DSA:1.10.10.10 1 84 8.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19155 dbb56b418edabc5cdb2a3dcb64cafc7a 303 Pfam PF03466 LysR substrate binding domain 89 300 2.1E-29 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS19155 dbb56b418edabc5cdb2a3dcb64cafc7a 303 Gene3D G3DSA:3.40.190.10 184 274 1.2E-14 T 28-03-2018 SMD44_RS19155 dbb56b418edabc5cdb2a3dcb64cafc7a 303 SUPERFAMILY SSF53850 89 301 1.54E-26 T 28-03-2018 SMD44_RS22220 f4c6f8dee32d5c85da7cc8d3ba5bdea1 121 Pfam PF08000 Bacterial PH domain 3 118 8.5E-46 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain SMD44_RS22220 f4c6f8dee32d5c85da7cc8d3ba5bdea1 121 SUPERFAMILY SSF50729 3 120 1.64E-43 T 28-03-2018 IPR011993 PH domain-like SMD44_RS22220 f4c6f8dee32d5c85da7cc8d3ba5bdea1 121 Gene3D G3DSA:2.30.29.50 9 98 5.2E-37 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 68 3.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 SUPERFAMILY SSF46689 17 77 8.98E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 Gene3D G3DSA:1.10.260.40 46 85 2.2E-6 T 28-03-2018 SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 SUPERFAMILY SSF48498 85 135 1.33E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 SUPERFAMILY SSF48498 163 232 8.23E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 PRINTS PR00400 Tetracycline repressor protein signature 87 106 6.3E-10 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 PRINTS PR00400 Tetracycline repressor protein signature 107 130 6.3E-10 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 PRINTS PR00400 Tetracycline repressor protein signature 36 59 6.3E-10 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 133 4.3E-9 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 Gene3D G3DSA:1.10.357.10 86 237 5.2E-22 T 28-03-2018 SMD44_RS03575 6ccb507fdd5e37265274145554361e75 245 Gene3D G3DSA:1.10.10.60 1 45 2.7E-7 T 28-03-2018 SMD44_RS13395 799b003b3f8230f07d4fb9bfe8d8593a 284 Gene3D G3DSA:3.20.10.10 133 280 7.1E-29 T 28-03-2018 SMD44_RS13395 799b003b3f8230f07d4fb9bfe8d8593a 284 SUPERFAMILY SSF56752 37 264 7.33E-36 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS13395 799b003b3f8230f07d4fb9bfe8d8593a 284 Pfam PF01063 Amino-transferase class IV 41 257 6.5E-29 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS13395 799b003b3f8230f07d4fb9bfe8d8593a 284 Gene3D G3DSA:3.30.470.10 25 127 7.7E-10 T 28-03-2018 SMD44_RS30545 583cfbf03f94a2889ff2a9d2f128a4db 345 Gene3D G3DSA:3.40.50.450 79 228 4.3E-39 T 28-03-2018 SMD44_RS30545 583cfbf03f94a2889ff2a9d2f128a4db 345 Gene3D G3DSA:1.10.10.10 257 330 6.6E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30545 583cfbf03f94a2889ff2a9d2f128a4db 345 SUPERFAMILY SSF102405 46 255 1.68E-36 T 28-03-2018 SMD44_RS30545 583cfbf03f94a2889ff2a9d2f128a4db 345 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 36 253 2.2E-62 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 SMD44_RS30545 583cfbf03f94a2889ff2a9d2f128a4db 345 Pfam PF02481 DNA recombination-mediator protein A 38 245 2.8E-68 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 SMD44_RS23690 369a502fbf645e177a3f9f0d0888eb56 352 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 53 234 2.5E-45 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMD44_RS23690 369a502fbf645e177a3f9f0d0888eb56 352 Pfam PF01171 PP-loop family 53 231 7.5E-40 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 SMD44_RS23690 369a502fbf645e177a3f9f0d0888eb56 352 SUPERFAMILY SSF52402 52 263 4.71E-47 T 28-03-2018 SMD44_RS23690 369a502fbf645e177a3f9f0d0888eb56 352 Gene3D G3DSA:3.40.50.620 52 271 9.8E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS23690 369a502fbf645e177a3f9f0d0888eb56 352 SUPERFAMILY SSF82829 243 347 1.49E-15 T 28-03-2018 SMD44_RS23690 369a502fbf645e177a3f9f0d0888eb56 352 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 27 341 20.508 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMD44_RS23690 369a502fbf645e177a3f9f0d0888eb56 352 Pfam PF09179 TilS substrate binding domain 280 347 6.3E-10 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMD44_RS29045 cd98864592d24dc10faffe493a301c51 226 SUPERFAMILY SSF46894 119 224 2.83E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS29045 cd98864592d24dc10faffe493a301c51 226 Gene3D G3DSA:1.10.10.10 119 226 9.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29045 cd98864592d24dc10faffe493a301c51 226 SMART SM00448 1 112 1.1E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS29045 cd98864592d24dc10faffe493a301c51 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 222 6.5E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS29045 cd98864592d24dc10faffe493a301c51 226 SUPERFAMILY SSF52172 1 133 1.04E-39 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS29045 cd98864592d24dc10faffe493a301c51 226 Gene3D G3DSA:3.40.50.2300 1 118 1.5E-34 T 28-03-2018 SMD44_RS29045 cd98864592d24dc10faffe493a301c51 226 SMART SM00862 151 222 4.5E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS29045 cd98864592d24dc10faffe493a301c51 226 Pfam PF00072 Response regulator receiver domain 4 112 5.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 Gene3D G3DSA:3.40.50.880 15 230 2.6E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 SUPERFAMILY SSF52317 19 214 5.34E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 SMART SM00342 248 331 2.1E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 Gene3D G3DSA:1.10.10.60 284 340 1.1E-13 T 28-03-2018 SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 Gene3D G3DSA:1.10.10.60 231 283 1.4E-12 T 28-03-2018 SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 SUPERFAMILY SSF46689 285 335 3.48E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 SUPERFAMILY SSF46689 235 282 2.58E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 Pfam PF01965 DJ-1/PfpI family 19 193 3.9E-11 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS18045 1782e94cdeaf5f17742821e60b3441b4 341 Pfam PF12833 Helix-turn-helix domain 255 332 7.1E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS14235 07b396cc9e8457be733e72768acb8c13 193 Pfam PF02632 BioY family 48 186 1.8E-31 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SMD44_RS14235 07b396cc9e8457be733e72768acb8c13 193 PIRSF PIRSF016661 11 193 4.1E-37 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SMD44_RS42875 a071b1a9b974703da0dad205c20983ad 296 Gene3D G3DSA:3.40.140.10 2 153 8.0E-26 T 28-03-2018 SMD44_RS42875 a071b1a9b974703da0dad205c20983ad 296 SUPERFAMILY SSF53927 8 145 1.0E-35 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMD44_RS42875 a071b1a9b974703da0dad205c20983ad 296 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 92 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMD44_RS42875 a071b1a9b974703da0dad205c20983ad 296 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 16 103 3.7E-14 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SMD44_RS20630 25b540bb9cdf74f9b0801f55f53a0f30 490 Pfam PF00557 Metallopeptidase family M24 230 464 5.5E-49 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS20630 25b540bb9cdf74f9b0801f55f53a0f30 490 SMART SM01011 55 196 6.9E-35 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SMD44_RS20630 25b540bb9cdf74f9b0801f55f53a0f30 490 SUPERFAMILY SSF53092 55 222 8.37E-26 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMD44_RS20630 25b540bb9cdf74f9b0801f55f53a0f30 490 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 398 410 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site SMD44_RS20630 25b540bb9cdf74f9b0801f55f53a0f30 490 Gene3D G3DSA:3.40.350.10 56 229 2.5E-33 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMD44_RS20630 25b540bb9cdf74f9b0801f55f53a0f30 490 Pfam PF05195 Aminopeptidase P, N-terminal domain 62 181 1.3E-18 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SMD44_RS20630 25b540bb9cdf74f9b0801f55f53a0f30 490 SUPERFAMILY SSF55920 223 485 1.7E-66 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS20630 25b540bb9cdf74f9b0801f55f53a0f30 490 Gene3D G3DSA:3.90.230.10 230 490 2.2E-66 T 28-03-2018 SMD44_RS09645 22e3a7382740b42d59180bf241483d51 273 Gene3D G3DSA:3.30.950.10 129 249 1.8E-23 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09645 22e3a7382740b42d59180bf241483d51 273 Gene3D G3DSA:3.40.1010.10 7 128 1.1E-31 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09645 22e3a7382740b42d59180bf241483d51 273 SUPERFAMILY SSF53790 6 256 1.44E-65 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09645 22e3a7382740b42d59180bf241483d51 273 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 10 256 5.6E-94 T 28-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 SMD44_RS09645 22e3a7382740b42d59180bf241483d51 273 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 216 5.8E-43 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS18865 d07da50fa58aa1010433b2df5291afec 147 SUPERFAMILY SSF75620 16 114 1.45E-12 T 28-03-2018 SMD44_RS18865 d07da50fa58aa1010433b2df5291afec 147 Pfam PF00472 RF-1 domain 16 141 2.3E-22 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD44_RS18865 d07da50fa58aa1010433b2df5291afec 147 Gene3D G3DSA:3.30.160.20 10 146 2.7E-35 T 28-03-2018 SMD44_RS31380 240207fa420b7e0720440272e97ac80b 500 Pfam PF01433 Peptidase family M1 domain 260 471 1.3E-25 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS31380 240207fa420b7e0720440272e97ac80b 500 Gene3D G3DSA:2.60.40.1730 54 235 4.6E-34 T 28-03-2018 SMD44_RS31380 240207fa420b7e0720440272e97ac80b 500 Gene3D G3DSA:1.10.390.10 321 475 1.1E-37 T 28-03-2018 SMD44_RS31380 240207fa420b7e0720440272e97ac80b 500 SUPERFAMILY SSF55486 244 479 4.64E-53 T 28-03-2018 SMD44_RS31380 240207fa420b7e0720440272e97ac80b 500 SUPERFAMILY SSF63737 45 234 6.8E-32 T 28-03-2018 SMD44_RS31380 240207fa420b7e0720440272e97ac80b 500 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 326 341 7.1E-12 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS31380 240207fa420b7e0720440272e97ac80b 500 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 171 186 7.1E-12 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS31380 240207fa420b7e0720440272e97ac80b 500 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 345 357 7.1E-12 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS21905 7ae27cf9afee87d0a4c30ab1aafccf54 130 SUPERFAMILY SSF54593 14 127 4.3E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS21905 7ae27cf9afee87d0a4c30ab1aafccf54 130 Gene3D G3DSA:3.10.180.10 10 129 2.8E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS15385 d9e8dca07f4b1544a93a55a082c9e56c 275 Gene3D G3DSA:1.10.3720.10 9 275 5.4E-33 T 28-03-2018 SMD44_RS15385 d9e8dca07f4b1544a93a55a082c9e56c 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 263 5.7E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15385 d9e8dca07f4b1544a93a55a082c9e56c 275 SUPERFAMILY SSF161098 5 271 4.32E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS04655 beb3f890b0288544ab07d46570f5a324 159 SUPERFAMILY SSF46894 103 156 6.8E-5 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS04655 beb3f890b0288544ab07d46570f5a324 159 Gene3D G3DSA:1.10.10.60 2 32 2.1E-7 T 28-03-2018 SMD44_RS04655 beb3f890b0288544ab07d46570f5a324 159 Gene3D G3DSA:1.10.10.10 33 117 0.17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04655 beb3f890b0288544ab07d46570f5a324 159 Pfam PF13384 Homeodomain-like domain 7 43 4.4E-6 T 28-03-2018 SMD44_RS04655 beb3f890b0288544ab07d46570f5a324 159 Gene3D G3DSA:1.10.10.60 118 158 4.9E-9 T 28-03-2018 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 311 326 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 151 166 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 332 341 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 188 210 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 341 352 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 134 150 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 283 310 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 87 98 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00359 B-class P450 signature 265 276 8.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 Pfam PF00067 Cytochrome P450 151 364 3.5E-27 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00385 P450 superfamily signature 332 341 2.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00385 P450 superfamily signature 265 276 2.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00385 P450 superfamily signature 230 247 2.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 PRINTS PR00385 P450 superfamily signature 341 352 2.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 Gene3D G3DSA:1.10.630.10 3 394 2.1E-68 T 28-03-2018 SMD44_RS31805 aeead823a308b0372e38b7993b2ba470 394 SUPERFAMILY SSF48264 12 394 3.27E-90 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS23175 efc655b972aa667be24b9b1053aab9a6 276 Pfam PF00753 Metallo-beta-lactamase superfamily 36 204 9.9E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS23175 efc655b972aa667be24b9b1053aab9a6 276 Gene3D G3DSA:3.60.15.10 36 267 8.0E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS23175 efc655b972aa667be24b9b1053aab9a6 276 SMART SM00849 39 204 1.8E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS23175 efc655b972aa667be24b9b1053aab9a6 276 SUPERFAMILY SSF56281 29 275 1.96E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 SUPERFAMILY SSF49303 559 668 4.17E-20 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Pfam PF02929 Beta galactosidase small chain 692 953 7.3E-56 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 SUPERFAMILY SSF49785 17 198 7.51E-55 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Gene3D G3DSA:2.60.120.260 6 198 1.4E-51 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 PRINTS PR00132 Glycosyl hydrolase family 2 signature 473 488 1.2E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 PRINTS PR00132 Glycosyl hydrolase family 2 signature 395 410 1.2E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 PRINTS PR00132 Glycosyl hydrolase family 2 signature 320 338 1.2E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 PRINTS PR00132 Glycosyl hydrolase family 2 signature 289 303 1.2E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 PRINTS PR00132 Glycosyl hydrolase family 2 signature 126 141 1.2E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Gene3D G3DSA:2.60.40.10 201 278 4.8E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Gene3D G3DSA:2.70.98.10 675 954 8.8E-79 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 SMART SM01038 686 954 2.0E-87 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 280 566 2.5E-103 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 SUPERFAMILY SSF49303 203 279 2.16E-11 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Gene3D G3DSA:2.60.40.10 563 670 4.6E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Pfam PF16353 Domain of unknown function(DUF4981) 576 665 1.1E-14 T 28-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 31 198 1.6E-37 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 330 355 - T 28-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 Gene3D G3DSA:3.20.20.80 279 562 2.5E-73 T 28-03-2018 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 395 409 - T 28-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 SUPERFAMILY SSF74650 691 953 1.73E-68 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD44_RS32905 5c0f09398070c869749d5fe9c4549181 960 SUPERFAMILY SSF51445 281 561 7.33E-89 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS35145 1aa7afd8d9684dfecf779e6909fb1cb2 288 SMART SM00882 5 227 2.7E-29 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMD44_RS35145 1aa7afd8d9684dfecf779e6909fb1cb2 288 Pfam PF01144 Coenzyme A transferase 8 206 3.2E-35 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMD44_RS35145 1aa7afd8d9684dfecf779e6909fb1cb2 288 SUPERFAMILY SSF100950 3 276 5.92E-70 T 28-03-2018 SMD44_RS35145 1aa7afd8d9684dfecf779e6909fb1cb2 288 Gene3D G3DSA:3.40.1080.10 1 250 7.3E-61 T 28-03-2018 SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 Pfam PF08281 Sigma-70, region 4 113 163 3.8E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 Gene3D G3DSA:1.10.1740.10 4 70 2.7E-13 T 28-03-2018 SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 Gene3D G3DSA:1.10.10.10 71 159 8.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 165 4.3E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 SUPERFAMILY SSF88659 111 166 8.72E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 Gene3D G3DSA:3.10.450.50 160 307 2.3E-16 T 28-03-2018 SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 SUPERFAMILY SSF54427 176 299 2.29E-12 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 Pfam PF04542 Sigma-70 region 2 14 77 3.3E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00540 03d05ab6077da6176981c58fb96a3aa7 317 SUPERFAMILY SSF88946 14 91 2.31E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS29520 6c852165947a36fe8ee399fa41ee295f 353 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS29520 6c852165947a36fe8ee399fa41ee295f 353 SMART SM00382 42 220 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29520 6c852165947a36fe8ee399fa41ee295f 353 Pfam PF00005 ABC transporter 34 171 4.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS29520 6c852165947a36fe8ee399fa41ee295f 353 SUPERFAMILY SSF52540 13 245 3.55E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29520 6c852165947a36fe8ee399fa41ee295f 353 Gene3D G3DSA:3.40.50.300 14 282 7.2E-64 T 28-03-2018 SMD44_RS24590 449140d7eb0db90d69c0e0513624e9ae 88 Pfam PF06013 Proteins of 100 residues with WXG 7 81 4.8E-10 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMD44_RS24590 449140d7eb0db90d69c0e0513624e9ae 88 Gene3D G3DSA:1.10.287.850 1 88 1.2E-13 T 28-03-2018 SMD44_RS24590 449140d7eb0db90d69c0e0513624e9ae 88 SUPERFAMILY SSF140453 7 82 1.96E-8 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 Gene3D G3DSA:3.40.50.2300 1 125 3.9E-38 T 28-03-2018 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 SMART SM00448 1 114 6.9E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 SUPERFAMILY SSF52172 1 130 1.85E-37 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 3.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 3.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 3.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 SMART SM00421 145 202 2.1E-28 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 Gene3D G3DSA:1.10.10.10 126 209 1.3E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 1.6E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 Pfam PF00072 Response regulator receiver domain 3 114 1.9E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS09305 df7218130a413c8b753df900991a34c8 209 SUPERFAMILY SSF46894 142 207 4.76E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS13550 43ee6c37251691c8c6b6b0f0040b8c49 297 SUPERFAMILY SSF81345 3 260 2.22E-34 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS13550 43ee6c37251691c8c6b6b0f0040b8c49 297 Gene3D G3DSA:1.10.3470.10 2 271 3.3E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS13550 43ee6c37251691c8c6b6b0f0040b8c49 297 Pfam PF00950 ABC 3 transport family 6 260 6.6E-66 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 SMD44_RS11220 f3113e94a769393146546f4ff0bb7a95 334 SUPERFAMILY SSF51735 101 297 6.88E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS11220 f3113e94a769393146546f4ff0bb7a95 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD44_RS11220 f3113e94a769393146546f4ff0bb7a95 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 327 7.5E-25 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMD44_RS11220 f3113e94a769393146546f4ff0bb7a95 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 296 1.4E-50 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD44_RS11220 f3113e94a769393146546f4ff0bb7a95 334 SUPERFAMILY SSF52283 2 134 1.74E-30 T 28-03-2018 SMD44_RS11220 f3113e94a769393146546f4ff0bb7a95 334 Gene3D G3DSA:3.40.50.720 3 115 5.3E-18 T 28-03-2018 SMD44_RS11220 f3113e94a769393146546f4ff0bb7a95 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMD44_RS11220 f3113e94a769393146546f4ff0bb7a95 334 Gene3D G3DSA:3.40.50.720 116 299 8.9E-48 T 28-03-2018 SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 Gene3D G3DSA:1.10.10.10 1 52 9.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 8.9E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 SUPERFAMILY SSF46785 1 60 1.32E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 SUPERFAMILY SSF54909 62 143 9.79E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 1.5E-18 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 SMART SM00344 1 108 3.1E-38 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.1E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.1E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.1E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS24420 c79f399dd93b805466101005eb4cd579 151 Gene3D G3DSA:3.30.70.920 54 135 7.0E-20 T 28-03-2018 SMD44_RS15235 a068bd93839e9b7c4b77b6ddd3690bc7 507 SUPERFAMILY SSF56322 18 500 1.3E-117 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS15235 a068bd93839e9b7c4b77b6ddd3690bc7 507 Pfam PF04715 Anthranilate synthase component I, N terminal region 19 179 4.2E-8 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS15235 a068bd93839e9b7c4b77b6ddd3690bc7 507 Gene3D G3DSA:3.60.120.10 94 505 8.4E-125 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS15235 a068bd93839e9b7c4b77b6ddd3690bc7 507 PRINTS PR00095 Anthranilate synthase component I signature 340 353 4.4E-14 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS15235 a068bd93839e9b7c4b77b6ddd3690bc7 507 PRINTS PR00095 Anthranilate synthase component I signature 434 448 4.4E-14 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS15235 a068bd93839e9b7c4b77b6ddd3690bc7 507 PRINTS PR00095 Anthranilate synthase component I signature 354 367 4.4E-14 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS15235 a068bd93839e9b7c4b77b6ddd3690bc7 507 PRINTS PR00095 Anthranilate synthase component I signature 449 463 4.4E-14 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS15235 a068bd93839e9b7c4b77b6ddd3690bc7 507 Pfam PF00425 chorismate binding enzyme 239 492 4.8E-84 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMD44_RS42770 2a73a261f19f1eec818786052483883a 139 Gene3D G3DSA:3.30.479.10 13 135 1.6E-31 T 28-03-2018 SMD44_RS42770 2a73a261f19f1eec818786052483883a 139 SUPERFAMILY SSF55620 15 133 6.12E-31 T 28-03-2018 SMD44_RS42770 2a73a261f19f1eec818786052483883a 139 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 134 1.8E-26 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 SMD44_RS42770 2a73a261f19f1eec818786052483883a 139 PIRSF PIRSF006113 13 136 1.3E-22 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 SMD44_RS21110 c53c7105bfa69c096e3e4f8cd96ca407 123 Pfam PF00825 Ribonuclease P 2 117 7.8E-27 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMD44_RS21110 c53c7105bfa69c096e3e4f8cd96ca407 123 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 112 2.8E-15 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMD44_RS21110 c53c7105bfa69c096e3e4f8cd96ca407 123 Gene3D G3DSA:3.30.230.10 1 119 1.6E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS21110 c53c7105bfa69c096e3e4f8cd96ca407 123 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 46 92 2.0E-4 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMD44_RS21110 c53c7105bfa69c096e3e4f8cd96ca407 123 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 120 16.153 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMD44_RS21110 c53c7105bfa69c096e3e4f8cd96ca407 123 SUPERFAMILY SSF54211 2 117 5.06E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS05720 ba3134c6e06f8629841e1fe4c9132091 176 Gene3D G3DSA:3.10.180.10 3 174 2.7E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS05720 ba3134c6e06f8629841e1fe4c9132091 176 SUPERFAMILY SSF54593 7 145 5.92E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS05720 ba3134c6e06f8629841e1fe4c9132091 176 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 139 7.8E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS33415 7a5bc86e82367678f2d9d2ed95b6db2e 192 Gene3D G3DSA:1.10.357.10 59 192 4.5E-26 T 28-03-2018 SMD44_RS33415 7a5bc86e82367678f2d9d2ed95b6db2e 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 7.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS33415 7a5bc86e82367678f2d9d2ed95b6db2e 192 Gene3D G3DSA:1.10.10.60 1 58 5.2E-18 T 28-03-2018 SMD44_RS33415 7a5bc86e82367678f2d9d2ed95b6db2e 192 SUPERFAMILY SSF46689 2 84 2.29E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS33415 7a5bc86e82367678f2d9d2ed95b6db2e 192 SUPERFAMILY SSF48498 78 192 5.69E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS20815 3742f1dab54652ca0ef71aeb295080f5 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 217 4.7E-80 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMD44_RS20815 3742f1dab54652ca0ef71aeb295080f5 339 PIRSF PIRSF000267 1 332 1.9E-121 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMD44_RS20815 3742f1dab54652ca0ef71aeb295080f5 339 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 1.6E-115 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMD44_RS05345 8df2075602ed2047df0a64acf2a0ab80 303 SUPERFAMILY SSF55729 6 293 4.13E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS05345 8df2075602ed2047df0a64acf2a0ab80 303 Gene3D G3DSA:3.40.630.30 1 176 9.5E-11 T 28-03-2018 SMD44_RS05345 8df2075602ed2047df0a64acf2a0ab80 303 Gene3D G3DSA:3.40.630.30 177 296 1.5E-6 T 28-03-2018 SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 SUPERFAMILY SSF52540 17 237 1.11E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 SUPERFAMILY SSF52540 285 501 3.86E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 SMART SM00382 295 489 0.0012 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 SMART SM00382 42 230 5.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 Gene3D G3DSA:3.40.50.300 275 510 1.3E-35 T 28-03-2018 SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 Gene3D G3DSA:3.40.50.300 14 267 1.3E-47 T 28-03-2018 SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 Pfam PF00005 ABC transporter 33 182 4.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS14775 07bcacd9bd549e541956ee8665891ced 559 Pfam PF00005 ABC transporter 287 440 2.0E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 Gene3D G3DSA:3.30.300.50 29 106 7.3E-23 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 Gene3D G3DSA:3.30.300.50 107 176 1.6E-13 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 318 329 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 SUPERFAMILY SSF50494 192 361 5.31E-33 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 Gene3D G3DSA:2.40.10.10 265 355 1.1E-17 T 28-03-2018 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 289 306 6.2E-40 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 268 288 6.2E-40 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 208 222 6.2E-40 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 309 332 6.2E-40 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 333 347 6.2E-40 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 PIRSF PIRSF001134 2 370 1.6E-121 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 Pfam PF00089 Trypsin 205 359 5.1E-11 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 Pfam PF02983 Alpha-lytic protease prodomain 110 167 8.5E-10 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD44_RS41060 5b14669e0f8a357d8f0becfa1c2358c6 370 Gene3D G3DSA:2.40.10.10 186 264 8.6E-17 T 28-03-2018 SMD44_RS02510 0e0213e2af7bae9a3aabdd693a8264d1 334 SMART SM00354 3 73 3.7E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS02510 0e0213e2af7bae9a3aabdd693a8264d1 334 SUPERFAMILY SSF53822 61 314 3.37E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS02510 0e0213e2af7bae9a3aabdd693a8264d1 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 1.0E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS02510 0e0213e2af7bae9a3aabdd693a8264d1 334 Gene3D G3DSA:3.40.50.2300 170 333 1.0E-41 T 28-03-2018 SMD44_RS02510 0e0213e2af7bae9a3aabdd693a8264d1 334 SUPERFAMILY SSF47413 4 61 3.52E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS02510 0e0213e2af7bae9a3aabdd693a8264d1 334 Gene3D G3DSA:3.40.50.2300 60 169 9.1E-30 T 28-03-2018 SMD44_RS02510 0e0213e2af7bae9a3aabdd693a8264d1 334 Gene3D G3DSA:1.10.260.40 4 59 5.1E-25 T 28-03-2018 SMD44_RS02510 0e0213e2af7bae9a3aabdd693a8264d1 334 Pfam PF13377 Periplasmic binding protein-like domain 172 330 1.3E-32 T 28-03-2018 SMD44_RS36330 eca47b9c4395cdefd73b0f5a2c2671fe 403 SUPERFAMILY SSF53850 3 401 4.25E-74 T 28-03-2018 SMD44_RS36330 eca47b9c4395cdefd73b0f5a2c2671fe 403 Pfam PF01547 Bacterial extracellular solute-binding protein 32 311 3.8E-34 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS36330 eca47b9c4395cdefd73b0f5a2c2671fe 403 Gene3D G3DSA:3.40.190.10 148 403 9.0E-34 T 28-03-2018 SMD44_RS36330 eca47b9c4395cdefd73b0f5a2c2671fe 403 Gene3D G3DSA:3.40.190.10 17 147 1.2E-25 T 28-03-2018 SMD44_RS14925 25370eb70a6c69ca724111cbe921e859 237 Gene3D G3DSA:3.40.50.880 3 231 2.6E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS14925 25370eb70a6c69ca724111cbe921e859 237 Pfam PF01965 DJ-1/PfpI family 10 168 3.3E-14 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS14925 25370eb70a6c69ca724111cbe921e859 237 SUPERFAMILY SSF52317 7 188 1.46E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 Gene3D G3DSA:3.40.630.30 357 490 9.2E-4 T 28-03-2018 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 616 1096 7.1E-138 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 20 227 5.6E-62 T 28-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 SUPERFAMILY SSF50249 613 746 7.83E-33 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 Gene3D G3DSA:2.40.50.140 614 746 6.6E-29 T 28-03-2018 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 620 1098 35.622 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 Gene3D G3DSA:3.30.930.10 747 1095 1.5E-81 T 28-03-2018 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 245 544 2.9E-106 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 PRINTS PR00982 Lysyl-tRNA synthetase signature 853 870 4.9E-30 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 PRINTS PR00982 Lysyl-tRNA synthetase signature 835 848 4.9E-30 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 PRINTS PR00982 Lysyl-tRNA synthetase signature 806 822 4.9E-30 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 PRINTS PR00982 Lysyl-tRNA synthetase signature 790 800 4.9E-30 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 PRINTS PR00982 Lysyl-tRNA synthetase signature 981 997 4.9E-30 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 SUPERFAMILY SSF55681 753 1096 2.79E-99 T 28-03-2018 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 Pfam PF01336 OB-fold nucleic acid binding domain 659 736 4.5E-11 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SMD44_RS37305 9d28547e1095c7e54a09d22dccbfbef6 1098 Pfam PF00152 tRNA synthetases class II (D, K and N) 755 1095 5.7E-68 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS23125 9b5d43816969545a4249ef300bb18750 311 SUPERFAMILY SSF56300 41 304 6.21E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS23125 9b5d43816969545a4249ef300bb18750 311 Gene3D G3DSA:3.60.21.10 44 308 2.1E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS23125 9b5d43816969545a4249ef300bb18750 311 Pfam PF00149 Calcineurin-like phosphoesterase 47 239 3.6E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 PRINTS PR00127 Clp protease catalytic subunit P signature 61 81 2.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 PRINTS PR00127 Clp protease catalytic subunit P signature 92 109 2.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 PRINTS PR00127 Clp protease catalytic subunit P signature 113 132 2.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 PRINTS PR00127 Clp protease catalytic subunit P signature 171 190 2.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 PRINTS PR00127 Clp protease catalytic subunit P signature 21 36 2.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 Pfam PF00574 Clp protease 15 195 3.0E-70 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 SUPERFAMILY SSF52096 13 198 9.17E-59 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 196 36.76 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40245 d239a5f404f7cf8cb6af0e00770433d5 201 Gene3D G3DSA:3.90.226.10 4 197 1.5E-37 T 28-03-2018 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 PRINTS PR00142 RecA protein signature 211 239 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 PRINTS PR00142 RecA protein signature 128 157 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 PRINTS PR00142 RecA protein signature 94 123 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 PRINTS PR00142 RecA protein signature 166 195 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 PRINTS PR00142 RecA protein signature 298 315 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 PRINTS PR00142 RecA protein signature 244 273 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 Gene3D G3DSA:3.40.50.300 27 269 2.2E-50 T 28-03-2018 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 SMART SM00382 58 229 7.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 SUPERFAMILY SSF54752 269 327 2.09E-21 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 Pfam PF00154 recA bacterial DNA recombination protein 8 269 4.2E-143 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 SUPERFAMILY SSF52540 5 268 5.01E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 3.0E-176 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 Gene3D G3DSA:3.30.250.10 271 327 3.7E-27 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 ProSitePatterns PS00321 recA signature. 214 222 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 SMD44_RS31220 8efad38eacfcd10fd0bf576f8d06069c 375 Hamap MF_00268 Protein RecA [recA]. 6 330 53.176 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD44_RS07340 a2450b12d6aaa087f09795ba0c600878 154 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 137 2.0E-31 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMD44_RS07340 a2450b12d6aaa087f09795ba0c600878 154 Pfam PF03652 Holliday junction resolvase 5 137 4.4E-43 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMD44_RS07340 a2450b12d6aaa087f09795ba0c600878 154 SMART SM00732 4 105 4.7E-34 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SMD44_RS07340 a2450b12d6aaa087f09795ba0c600878 154 SUPERFAMILY SSF53098 4 138 7.89E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS07340 a2450b12d6aaa087f09795ba0c600878 154 Gene3D G3DSA:3.30.420.140 2 148 4.7E-45 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SMD44_RS07340 a2450b12d6aaa087f09795ba0c600878 154 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 140 22.912 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMD44_RS11585 9960c4996edd9b0bbd68fe962b7e82bf 306 Gene3D G3DSA:3.40.50.720 11 306 1.8E-36 T 28-03-2018 SMD44_RS11585 9960c4996edd9b0bbd68fe962b7e82bf 306 SUPERFAMILY SSF51735 10 305 8.71E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS11585 9960c4996edd9b0bbd68fe962b7e82bf 306 Pfam PF08338 Domain of unknown function (DUF1731) 258 303 5.5E-18 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 SMD44_RS11585 9960c4996edd9b0bbd68fe962b7e82bf 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 14 222 2.0E-13 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS11585 9960c4996edd9b0bbd68fe962b7e82bf 306 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 13 301 1.7E-101 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 SMD44_RS16845 31b80dc2f9f7bbed6c3d867e2d91ada6 247 Gene3D G3DSA:3.40.630.30 5 213 8.4E-21 T 28-03-2018 SMD44_RS16845 31b80dc2f9f7bbed6c3d867e2d91ada6 247 SUPERFAMILY SSF55729 100 147 4.22E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS16845 31b80dc2f9f7bbed6c3d867e2d91ada6 247 SUPERFAMILY SSF55729 13 69 4.22E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS01160 21b7c51a2444d980b4184b0fdb6c377d 238 SUPERFAMILY SSF55166 20 206 3.73E-45 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS01160 21b7c51a2444d980b4184b0fdb6c377d 238 Pfam PF01427 D-ala-D-ala dipeptidase 56 203 1.9E-18 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD44_RS01160 21b7c51a2444d980b4184b0fdb6c377d 238 Gene3D G3DSA:3.30.1380.10 25 207 4.8E-38 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS01160 21b7c51a2444d980b4184b0fdb6c377d 238 PIRSF PIRSF026671 1 214 1.6E-45 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD44_RS01160 21b7c51a2444d980b4184b0fdb6c377d 238 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 6 208 23.778 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD44_RS34900 f7af76635108b27dd038e2e768c79a12 277 Gene3D G3DSA:1.10.260.40 2 85 4.7E-15 T 28-03-2018 SMD44_RS34900 f7af76635108b27dd038e2e768c79a12 277 SMART SM00530 18 73 1.0E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS34900 f7af76635108b27dd038e2e768c79a12 277 Pfam PF13560 Helix-turn-helix domain 14 75 5.2E-15 T 28-03-2018 SMD44_RS34900 f7af76635108b27dd038e2e768c79a12 277 SUPERFAMILY SSF47413 14 70 7.6E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 Pfam PF13305 WHG domain 90 166 3.3E-14 T 28-03-2018 IPR025996 WHG domain SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 Gene3D G3DSA:1.10.260.40 37 65 3.5E-13 T 28-03-2018 SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 1.2E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 SUPERFAMILY SSF46689 4 77 4.04E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 Gene3D G3DSA:1.10.10.60 2 36 5.3E-13 T 28-03-2018 SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 Gene3D G3DSA:1.10.357.10 66 198 2.4E-17 T 28-03-2018 SMD44_RS00775 afc58b43236f94b4d0b704c5f47fc160 210 SUPERFAMILY SSF48498 89 168 9.04E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 Gene3D G3DSA:3.20.20.80 165 607 5.2E-114 T 28-03-2018 SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 SMART SM00642 184 595 7.8E-9 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 Pfam PF00128 Alpha amylase, catalytic domain 215 319 2.0E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 SUPERFAMILY SSF51011 616 727 2.81E-19 T 28-03-2018 SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 SUPERFAMILY SSF81296 3 161 5.0E-35 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 8 108 3.0E-16 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 4 726 5.2E-299 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 Gene3D G3DSA:2.60.40.10 4 159 1.3E-42 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 SUPERFAMILY SSF51445 161 496 4.7E-131 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 SUPERFAMILY SSF51445 525 603 4.7E-131 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS29555 e30a14e1a63f4f9c6770544cb56d2711 750 Gene3D G3DSA:2.60.40.1180 608 730 2.9E-31 T 28-03-2018 SMD44_RS14535 47aeb9a7083a0db2c18a7cb3391b4f11 157 Pfam PF03061 Thioesterase superfamily 18 96 2.0E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMD44_RS14535 47aeb9a7083a0db2c18a7cb3391b4f11 157 SUPERFAMILY SSF54637 4 137 5.4E-34 T 28-03-2018 IPR029069 HotDog domain SMD44_RS14535 47aeb9a7083a0db2c18a7cb3391b4f11 157 Gene3D G3DSA:3.10.129.10 1 139 3.8E-34 T 28-03-2018 SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 Gene3D G3DSA:3.40.50.720 54 160 0.0034 T 28-03-2018 SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 234 413 1.2E-5 T 28-03-2018 SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 Gene3D G3DSA:3.40.50.720 406 465 3.7E-8 T 28-03-2018 SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 SUPERFAMILY SSF51735 230 464 5.0E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 240 461 5.5E-44 T 28-03-2018 SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 376 395 6.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 303 314 6.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 356 364 6.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 431 451 2.7E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 398 415 2.7E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 235 252 2.7E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 303 314 2.7E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 376 395 2.7E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 350 366 2.7E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 363 391 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 Gene3D G3DSA:3.40.50.720 215 405 1.0E-49 T 28-03-2018 SMD44_RS24450 295256e26abeecb856727fd2657b198d 468 Gene3D G3DSA:3.40.50.720 161 189 0.29 T 28-03-2018 SMD44_RS41405 34e895c86e847f1cb2bfa23a1837bf58 102 Pfam PF13616 PPIC-type PPIASE domain 8 100 2.8E-24 T 28-03-2018 SMD44_RS41405 34e895c86e847f1cb2bfa23a1837bf58 102 SUPERFAMILY SSF54534 4 98 4.91E-31 T 28-03-2018 SMD44_RS41405 34e895c86e847f1cb2bfa23a1837bf58 102 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 39 59 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 SMD44_RS41405 34e895c86e847f1cb2bfa23a1837bf58 102 Gene3D G3DSA:3.10.50.40 4 99 2.0E-33 T 28-03-2018 SMD44_RS23870 e90a923a974b26eb58f0dd3c2f5cd451 112 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 111 4.0E-38 T 28-03-2018 IPR024412 Lsr2 SMD44_RS23870 e90a923a974b26eb58f0dd3c2f5cd451 112 Pfam PF11774 Lsr2 2 110 1.6E-40 T 28-03-2018 IPR024412 Lsr2 SMD44_RS36485 0415512c6e2e2482d968e843520e73bf 433 SUPERFAMILY SSF51735 7 126 8.27E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36485 0415512c6e2e2482d968e843520e73bf 433 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 139 319 1.2E-49 T 28-03-2018 SMD44_RS36485 0415512c6e2e2482d968e843520e73bf 433 Pfam PF08659 KR domain 139 318 8.8E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36485 0415512c6e2e2482d968e843520e73bf 433 Gene3D G3DSA:3.40.50.720 129 417 6.9E-46 T 28-03-2018 SMD44_RS36485 0415512c6e2e2482d968e843520e73bf 433 SUPERFAMILY SSF51735 136 342 1.3E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 111 723 1.3E-233 T 28-03-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 PIRSF PIRSF000460 1 806 5.5E-254 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 Gene3D G3DSA:3.40.50.2000 119 430 9.7E-89 T 28-03-2018 SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 SUPERFAMILY SSF53756 4 751 4.31E-200 T 28-03-2018 SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 Pfam PF11897 Protein of unknown function (DUF3417) 13 124 9.3E-34 T 28-03-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 611 623 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 Pfam PF00343 Carbohydrate phosphorylase 303 633 2.8E-13 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 Pfam PF00343 Carbohydrate phosphorylase 129 174 2.9E-6 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMD44_RS29480 7eb1a2688bd720d26e560fedd86d9c40 876 Gene3D G3DSA:3.40.50.2000 431 748 6.4E-80 T 28-03-2018 SMD44_RS17820 8c4e89b0d15f82c43f995397472cf9e6 286 Pfam PF07690 Major Facilitator Superfamily 5 246 3.1E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS17820 8c4e89b0d15f82c43f995397472cf9e6 286 SUPERFAMILY SSF103473 3 168 3.53E-18 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17820 8c4e89b0d15f82c43f995397472cf9e6 286 SUPERFAMILY SSF103473 201 264 3.53E-18 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17820 8c4e89b0d15f82c43f995397472cf9e6 286 Gene3D G3DSA:1.20.1250.20 1 161 4.3E-15 T 28-03-2018 SMD44_RS43665 4e54667c71051b0bc4f466c745c1b3a2 314 Gene3D G3DSA:1.10.530.10 16 180 8.3E-38 T 28-03-2018 SMD44_RS43665 4e54667c71051b0bc4f466c745c1b3a2 314 Pfam PF00877 NlpC/P60 family 202 310 5.4E-19 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS43665 4e54667c71051b0bc4f466c745c1b3a2 314 SUPERFAMILY SSF53955 54 176 8.66E-34 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS43665 4e54667c71051b0bc4f466c745c1b3a2 314 Gene3D G3DSA:3.90.1720.10 181 314 1.0E-32 T 28-03-2018 SMD44_RS43665 4e54667c71051b0bc4f466c745c1b3a2 314 SUPERFAMILY SSF54001 185 309 4.25E-31 T 28-03-2018 SMD44_RS43665 4e54667c71051b0bc4f466c745c1b3a2 314 Pfam PF01464 Transglycosylase SLT domain 52 156 7.1E-16 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SMD44_RS42160 bacb3b3633a38648e42334e9433e7b90 366 Gene3D G3DSA:2.30.38.10 1 82 7.2E-26 T 28-03-2018 SMD44_RS42160 bacb3b3633a38648e42334e9433e7b90 366 Pfam PF00501 AMP-binding enzyme 3 92 9.0E-26 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS42160 bacb3b3633a38648e42334e9433e7b90 366 Gene3D G3DSA:3.30.300.30 86 188 5.9E-32 T 28-03-2018 SMD44_RS42160 bacb3b3633a38648e42334e9433e7b90 366 Pfam PF13193 AMP-binding enzyme C-terminal domain 100 172 2.6E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS42160 bacb3b3633a38648e42334e9433e7b90 366 SUPERFAMILY SSF56801 2 182 1.83E-59 T 28-03-2018 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 209 224 6.4E-11 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 330 6.4E-11 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 162 177 6.4E-11 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 334 346 6.4E-11 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 SUPERFAMILY SSF55486 246 462 4.69E-50 T 28-03-2018 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 Gene3D G3DSA:1.10.390.10 309 459 3.6E-36 T 28-03-2018 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 SUPERFAMILY SSF63737 35 225 5.62E-35 T 28-03-2018 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 Pfam PF01433 Peptidase family M1 domain 309 455 2.7E-27 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS35375 87a7f87e7394a536d781ef83c4f7c42d 504 Gene3D G3DSA:2.60.40.1730 44 227 6.6E-42 T 28-03-2018 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 492 5.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 SUPERFAMILY SSF47384 262 344 8.63E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 279 344 1.5E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 Gene3D G3DSA:3.30.565.10 332 501 3.5E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 SMART SM00388 277 344 6.3E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 SUPERFAMILY SSF158472 219 265 2.75E-8 T 28-03-2018 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 Gene3D G3DSA:1.10.287.130 267 331 9.6E-17 T 28-03-2018 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 SUPERFAMILY SSF55874 333 495 1.23E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 Pfam PF00672 HAMP domain 218 265 8.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 435 5.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 449 5.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 473 5.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 492 5.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 SMART SM00304 217 269 8.9E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS18715 8c199b6c62ee25177215f8449519be42 501 SMART SM00387 384 495 2.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 PIRSF PIRSF001400 3 424 3.3E-188 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 142 422 4.7E-134 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 PRINTS PR00148 Enolase signature 334 348 5.8E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 PRINTS PR00148 Enolase signature 39 53 5.8E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 PRINTS PR00148 Enolase signature 163 176 5.8E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 PRINTS PR00148 Enolase signature 311 322 5.8E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 PRINTS PR00148 Enolase signature 363 380 5.8E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 PRINTS PR00148 Enolase signature 109 125 5.8E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 SUPERFAMILY SSF51604 140 424 9.96E-133 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 SUPERFAMILY SSF54826 6 140 1.49E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 SMART SM01192 141 425 4.3E-230 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 ProSitePatterns PS00164 Enolase signature. 334 347 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 6 425 9.8E-205 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 SMART SM01193 6 136 1.2E-85 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 Pfam PF03952 Enolase, N-terminal domain 6 136 5.4E-55 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 Gene3D G3DSA:3.20.20.120 130 427 3.5E-106 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 Gene3D G3DSA:3.30.390.10 5 129 3.4E-49 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS16790 e90e7028838d824429e97255bb1ebb06 428 Hamap MF_00318 Enolase [eno]. 4 411 45.12 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 216 1.1E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 200 1.1E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 228 1.1E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 Pfam PF00072 Response regulator receiver domain 32 149 1.2E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 Pfam PF00196 Bacterial regulatory proteins, luxR family 185 240 8.2E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 Gene3D G3DSA:1.10.10.10 161 246 4.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 SUPERFAMILY SSF46894 176 245 3.74E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 SMART SM00448 30 149 1.0E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 SUPERFAMILY SSF52172 29 167 1.38E-21 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 SMART SM00421 183 240 2.1E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 Gene3D G3DSA:3.40.50.2300 29 160 2.2E-22 T 28-03-2018 SMD44_RS25940 dff29c03beb174d4bc8ac30db2938ea6 246 ProSitePatterns PS00622 LuxR-type HTH domain signature. 200 227 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17370 9f76f7a006ef26d70dd7e064dc07deef 385 Pfam PF03576 Peptidase family S58 16 373 3.7E-66 T 28-03-2018 IPR005321 Peptidase S58, DmpA SMD44_RS17370 9f76f7a006ef26d70dd7e064dc07deef 385 Gene3D G3DSA:3.60.70.12 7 385 1.9E-118 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS17370 9f76f7a006ef26d70dd7e064dc07deef 385 SUPERFAMILY SSF56266 223 371 8.76E-23 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS17370 9f76f7a006ef26d70dd7e064dc07deef 385 SUPERFAMILY SSF56266 10 219 3.66E-40 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 8.9E-35 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 8.9E-35 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 328 8.9E-35 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 293 8.9E-35 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 8.9E-35 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 Gene3D G3DSA:1.10.287.990 50 109 1.4E-14 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 Gene3D G3DSA:3.30.390.30 354 475 1.4E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 193 218 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 328 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 292 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 2.9E-53 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 Gene3D G3DSA:3.40.50.20 4 49 3.5E-4 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 PIRSF PIRSF000350 2 477 1.1E-75 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 SUPERFAMILY SSF55424 360 474 7.9E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 SUPERFAMILY SSF51905 142 350 5.54E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 SUPERFAMILY SSF51905 4 93 5.54E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 Gene3D G3DSA:3.40.50.720 182 350 1.5E-31 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 Gene3D G3DSA:3.30.9.10 110 175 0.045 T 28-03-2018 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 341 2.8E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26940 6013779cd990a007250ed367b49afdd1 482 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 362 468 8.9E-25 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 Pfam PF00041 Fibronectin type III domain 136 206 1.3E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 Pfam PF00041 Fibronectin type III domain 231 301 1.1E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 Gene3D G3DSA:3.20.20.80 316 749 2.5E-86 T 28-03-2018 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SMART SM00637 26 126 8.7E-20 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 Pfam PF00704 Glycosyl hydrolases family 18 327 734 1.6E-79 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SUPERFAMILY SSF49384 22 127 8.37E-18 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 ProSitePatterns PS01095 Chitinases family 18 active site. 494 502 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SUPERFAMILY SSF51445 321 633 4.04E-85 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SUPERFAMILY SSF51445 704 740 4.04E-85 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SMART SM00060 229 305 2.4E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SMART SM00060 134 209 1.0E-10 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 Pfam PF00553 Cellulose binding domain 36 126 1.2E-13 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SUPERFAMILY SSF49265 133 317 7.79E-26 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 Gene3D G3DSA:2.60.40.10 227 315 1.2E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 Gene3D G3DSA:2.60.40.10 130 226 8.3E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SMART SM00636 324 734 5.5E-114 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 Gene3D G3DSA:2.60.40.290 17 126 2.0E-20 T 28-03-2018 SMD44_RS26905 266b6d93fa78f89d9078aac7eca7afd0 749 SUPERFAMILY SSF54556 635 706 6.54E-11 T 28-03-2018 IPR029070 Chitinase insertion domain SMD44_RS23130 c0c47b011e9332a53241b59419cd1fe1 155 SUPERFAMILY SSF89095 3 152 3.4E-36 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SMD44_RS23130 c0c47b011e9332a53241b59419cd1fe1 155 Pfam PF09424 Yqey-like protein 5 152 2.2E-46 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial SMD44_RS23130 c0c47b011e9332a53241b59419cd1fe1 155 Gene3D G3DSA:1.10.1510.10 1 93 3.8E-26 T 28-03-2018 SMD44_RS23130 c0c47b011e9332a53241b59419cd1fe1 155 Gene3D G3DSA:1.10.10.410 94 153 8.2E-17 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal SMD44_RS26330 c63d5a176accf59dea5c117e4c44099d 337 Gene3D G3DSA:1.10.10.10 91 168 0.44 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26330 c63d5a176accf59dea5c117e4c44099d 337 Pfam PF13280 WYL domain 146 317 5.6E-27 T 28-03-2018 IPR026881 WYL domain SMD44_RS26330 c63d5a176accf59dea5c117e4c44099d 337 SUPERFAMILY SSF46785 2 57 3.96E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26330 c63d5a176accf59dea5c117e4c44099d 337 PIRSF PIRSF016838 1 53 3.4E-4 T 28-03-2018 IPR028349 Protein PafC SMD44_RS26330 c63d5a176accf59dea5c117e4c44099d 337 PIRSF PIRSF016838 69 325 5.9E-12 T 28-03-2018 IPR028349 Protein PafC SMD44_RS26330 c63d5a176accf59dea5c117e4c44099d 337 Pfam PF08279 HTH domain 10 57 2.9E-15 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SMD44_RS26330 c63d5a176accf59dea5c117e4c44099d 337 Gene3D G3DSA:1.10.10.10 1 64 2.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18815 5dac3c627717736bfc0ea357cb01e8bb 464 Gene3D G3DSA:3.40.50.2000 7 256 3.1E-65 T 28-03-2018 SMD44_RS18815 5dac3c627717736bfc0ea357cb01e8bb 464 SUPERFAMILY SSF53756 11 461 1.0E-110 T 28-03-2018 SMD44_RS18815 5dac3c627717736bfc0ea357cb01e8bb 464 Pfam PF00982 Glycosyltransferase family 20 11 462 5.2E-102 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 SMD44_RS18815 5dac3c627717736bfc0ea357cb01e8bb 464 Gene3D G3DSA:3.40.50.2000 257 445 5.2E-37 T 28-03-2018 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SMART SM00862 16 87 1.9E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SMART SM00028 829 862 25.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SMART SM00028 869 902 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SMART SM00028 910 943 25.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SUPERFAMILY SSF48452 769 945 8.73E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 Gene3D G3DSA:1.25.40.10 813 966 1.3E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 Gene3D G3DSA:1.10.10.10 1 90 2.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SMART SM01043 94 236 1.4E-50 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 Gene3D G3DSA:3.40.50.300 250 395 6.3E-14 T 28-03-2018 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 Gene3D G3DSA:1.25.40.10 91 249 9.5E-28 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 Pfam PF03704 Bacterial transcriptional activator domain 94 236 6.3E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SUPERFAMILY SSF48452 89 255 2.09E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SUPERFAMILY SSF52540 245 515 3.8E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 Gene3D G3DSA:1.25.40.10 734 812 0.0014 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 76 2.7E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 SUPERFAMILY SSF46894 3 87 1.9E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 PRINTS PR00364 Disease resistance protein signature 450 464 6.3E-7 T 28-03-2018 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 PRINTS PR00364 Disease resistance protein signature 273 288 6.3E-7 T 28-03-2018 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 PRINTS PR00364 Disease resistance protein signature 352 366 6.3E-7 T 28-03-2018 SMD44_RS30315 e9d55508b990597971c0401f4c7a4482 1021 Pfam PF13424 Tetratricopeptide repeat 830 899 2.3E-9 T 28-03-2018 SMD44_RS01865 e25a71638661ca98f4a1bd44369f1621 448 SMART SM00829 48 412 7.1E-10 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS01865 e25a71638661ca98f4a1bd44369f1621 448 SUPERFAMILY SSF50129 50 227 1.45E-28 T 28-03-2018 IPR011032 GroES-like SMD44_RS01865 e25a71638661ca98f4a1bd44369f1621 448 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 64 187 9.5E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS01865 e25a71638661ca98f4a1bd44369f1621 448 Gene3D G3DSA:3.90.180.10 18 413 1.6E-64 T 28-03-2018 SMD44_RS01865 e25a71638661ca98f4a1bd44369f1621 448 SUPERFAMILY SSF51735 192 382 1.67E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01865 e25a71638661ca98f4a1bd44369f1621 448 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 32 425 2.8E-169 T 28-03-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 SMD44_RS01865 e25a71638661ca98f4a1bd44369f1621 448 Pfam PF00107 Zinc-binding dehydrogenase 233 375 1.6E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS01865 e25a71638661ca98f4a1bd44369f1621 448 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 222 243 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 Pfam PF00958 GMP synthase C terminal domain 433 525 1.3E-38 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 207 526 3.3E-146 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 12 194 8.2E-73 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 SUPERFAMILY SSF52317 12 200 2.6E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 9 526 53.466 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 83 94 9.3E-8 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 172 185 9.3E-8 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 56 65 9.3E-8 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 Pfam PF02540 NAD synthase 218 287 4.2E-7 T 28-03-2018 IPR022310 NAD/GMP synthase SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 Gene3D G3DSA:3.40.50.880 9 196 2.6E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 SUPERFAMILY SSF52402 188 446 1.83E-56 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 Gene3D G3DSA:3.40.50.620 204 400 2.1E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 Pfam PF00117 Glutamine amidotransferase class-I 14 194 7.6E-41 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 SUPERFAMILY SSF54810 405 526 9.15E-47 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 Gene3D G3DSA:3.30.300.10 401 526 2.8E-51 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00097 Anthranilate synthase component II signature 56 65 1.1E-5 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00097 Anthranilate synthase component II signature 83 94 1.1E-5 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00097 Anthranilate synthase component II signature 172 185 1.1E-5 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 53 67 7.8E-6 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 83 99 7.8E-6 T 28-03-2018 SMD44_RS25900 4df6d7e8652ca20465bb8115be8519e8 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 12 26 7.8E-6 T 28-03-2018 SMD44_RS25040 eda34f2771231b43c1ae405c32f41159 285 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 35 176 2.0E-45 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25040 eda34f2771231b43c1ae405c32f41159 285 Gene3D G3DSA:3.40.30.10 95 186 1.0E-15 T 28-03-2018 SMD44_RS25040 eda34f2771231b43c1ae405c32f41159 285 SUPERFAMILY SSF52833 29 186 1.57E-49 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS25040 eda34f2771231b43c1ae405c32f41159 285 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 134 152 - T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25040 eda34f2771231b43c1ae405c32f41159 285 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 34 176 4.9E-51 T 28-03-2018 SMD44_RS23475 54499b7de2c980ae74dec9c7f442fb3b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 119 132 2.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23475 54499b7de2c980ae74dec9c7f442fb3b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 2.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23475 54499b7de2c980ae74dec9c7f442fb3b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 2.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23475 54499b7de2c980ae74dec9c7f442fb3b 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 2.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23475 54499b7de2c980ae74dec9c7f442fb3b 276 Gene3D G3DSA:3.40.50.1820 3 275 3.8E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23475 54499b7de2c980ae74dec9c7f442fb3b 276 SUPERFAMILY SSF53474 8 273 8.71E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23475 54499b7de2c980ae74dec9c7f442fb3b 276 Pfam PF12697 Alpha/beta hydrolase family 33 267 1.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 Gene3D G3DSA:1.10.579.10 280 454 7.8E-63 T 28-03-2018 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 SUPERFAMILY SSF48173 188 450 2.35E-90 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 Pfam PF00875 DNA photolyase 4 160 1.3E-37 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 Gene3D G3DSA:1.25.40.80 130 278 5.3E-32 T 28-03-2018 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 Gene3D G3DSA:3.40.50.620 1 128 2.0E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 312 324 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 Pfam PF03441 FAD binding domain of DNA photolyase 262 449 1.7E-71 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 PRINTS PR00147 DNA photolyase signature 332 350 4.2E-25 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 PRINTS PR00147 DNA photolyase signature 141 157 4.2E-25 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 PRINTS PR00147 DNA photolyase signature 312 328 4.2E-25 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 PRINTS PR00147 DNA photolyase signature 371 385 4.2E-25 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 332 351 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal SMD44_RS02225 ec708de345393a4e568bbd4f5956c8fb 457 SUPERFAMILY SSF52425 4 183 1.96E-37 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMD44_RS15890 d3f3416c75561162c2a98f73901773bd 750 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 603 611 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD44_RS15890 d3f3416c75561162c2a98f73901773bd 750 SUPERFAMILY SSF54292 565 641 1.52E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS15890 d3f3416c75561162c2a98f73901773bd 750 Pfam PF01799 [2Fe-2S] binding domain 637 709 2.5E-23 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS15890 d3f3416c75561162c2a98f73901773bd 750 SUPERFAMILY SSF47741 648 718 1.83E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS15890 d3f3416c75561162c2a98f73901773bd 750 Gene3D G3DSA:3.10.20.30 563 638 3.2E-19 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS15890 d3f3416c75561162c2a98f73901773bd 750 Gene3D G3DSA:1.10.150.120 639 743 5.4E-31 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS13305 a2c955d087d9d8369899ae813d781619 480 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 246 430 1.8E-16 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD44_RS13305 a2c955d087d9d8369899ae813d781619 480 PIRSF PIRSF000538 1 471 6.0E-60 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD44_RS13305 a2c955d087d9d8369899ae813d781619 480 SUPERFAMILY SSF53067 241 453 6.74E-33 T 28-03-2018 SMD44_RS13305 a2c955d087d9d8369899ae813d781619 480 SUPERFAMILY SSF53067 4 241 8.2E-34 T 28-03-2018 SMD44_RS13305 a2c955d087d9d8369899ae813d781619 480 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 237 1.0E-33 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD44_RS13305 a2c955d087d9d8369899ae813d781619 480 Gene3D G3DSA:3.30.420.40 1 242 4.4E-50 T 28-03-2018 SMD44_RS13305 a2c955d087d9d8369899ae813d781619 480 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 342 363 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD44_RS13305 a2c955d087d9d8369899ae813d781619 480 Gene3D G3DSA:3.30.420.40 243 471 6.1E-40 T 28-03-2018 SMD44_RS03580 dcfcc42401527329b41a6e4c657d6f8c 158 SUPERFAMILY SSF54593 3 155 3.87E-50 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS03580 dcfcc42401527329b41a6e4c657d6f8c 158 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 117 4.0E-50 T 28-03-2018 IPR028973 PhnB-like SMD44_RS03580 dcfcc42401527329b41a6e4c657d6f8c 158 PIRSF PIRSF021700 1 157 1.2E-66 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase SMD44_RS03580 dcfcc42401527329b41a6e4c657d6f8c 158 Gene3D G3DSA:3.10.180.10 1 127 3.0E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS25870 65cd9b9fbb514cb660d8a9e5c2f90461 538 SUPERFAMILY SSF53720 44 505 8.12E-137 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS25870 65cd9b9fbb514cb660d8a9e5c2f90461 538 Pfam PF00171 Aldehyde dehydrogenase family 47 502 2.0E-139 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS25870 65cd9b9fbb514cb660d8a9e5c2f90461 538 Gene3D G3DSA:3.40.605.10 35 290 8.9E-74 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS25870 65cd9b9fbb514cb660d8a9e5c2f90461 538 Gene3D G3DSA:3.40.309.10 291 487 2.4E-62 T 28-03-2018 SMD44_RS25870 65cd9b9fbb514cb660d8a9e5c2f90461 538 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 274 281 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS34560 bb5a30bd9bb5e544e639554d11addce9 273 SUPERFAMILY SSF48613 18 241 3.11E-59 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS34560 bb5a30bd9bb5e544e639554d11addce9 273 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 273 99.41 T 28-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 SMD44_RS34560 bb5a30bd9bb5e544e639554d11addce9 273 Pfam PF03070 TENA/THI-4/PQQC family 28 237 3.2E-44 T 28-03-2018 IPR004305 Thiaminase-2/PQQC SMD44_RS34560 bb5a30bd9bb5e544e639554d11addce9 273 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 21 240 4.6E-84 T 28-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 SMD44_RS34560 bb5a30bd9bb5e544e639554d11addce9 273 Gene3D G3DSA:1.20.910.10 14 248 1.2E-35 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS06805 f0c38404fbd2b289d70dc821283d7134 234 Gene3D G3DSA:1.10.10.10 7 83 9.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06805 f0c38404fbd2b289d70dc821283d7134 234 SUPERFAMILY SSF48008 86 220 1.6E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS06805 f0c38404fbd2b289d70dc821283d7134 234 Gene3D G3DSA:1.20.120.530 84 229 1.4E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS06805 f0c38404fbd2b289d70dc821283d7134 234 SMART SM00345 23 81 2.0E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06805 f0c38404fbd2b289d70dc821283d7134 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 81 7.6E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06805 f0c38404fbd2b289d70dc821283d7134 234 SUPERFAMILY SSF46785 15 85 1.16E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06805 f0c38404fbd2b289d70dc821283d7134 234 SMART SM00895 91 213 1.4E-12 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS06805 f0c38404fbd2b289d70dc821283d7134 234 Pfam PF07729 FCD domain 91 207 5.5E-12 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS41050 bd9b95c697fa5534a2423985d7b67a0e 294 Pfam PF12833 Helix-turn-helix domain 191 268 7.3E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS41050 bd9b95c697fa5534a2423985d7b67a0e 294 Gene3D G3DSA:1.10.10.60 226 276 3.1E-6 T 28-03-2018 SMD44_RS41050 bd9b95c697fa5534a2423985d7b67a0e 294 Gene3D G3DSA:1.10.10.60 35 225 1.8E-8 T 28-03-2018 SMD44_RS41050 bd9b95c697fa5534a2423985d7b67a0e 294 SMART SM00342 185 267 3.3E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS36465 b48e504ecb71032f66affc01851c473c 262 Gene3D G3DSA:3.30.470.10 4 95 1.1E-12 T 28-03-2018 SMD44_RS36465 b48e504ecb71032f66affc01851c473c 262 SUPERFAMILY SSF56752 9 243 4.32E-46 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS36465 b48e504ecb71032f66affc01851c473c 262 Gene3D G3DSA:3.20.10.10 108 260 1.5E-34 T 28-03-2018 SMD44_RS36465 b48e504ecb71032f66affc01851c473c 262 Pfam PF01063 Amino-transferase class IV 23 234 5.5E-34 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS02260 8a5973df16f124da6e39a70ce761996c 730 Pfam PF01204 Trehalase 482 705 6.4E-14 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 SMD44_RS02260 8a5973df16f124da6e39a70ce761996c 730 Gene3D G3DSA:1.50.10.10 311 729 4.7E-90 T 28-03-2018 SMD44_RS02260 8a5973df16f124da6e39a70ce761996c 730 Gene3D G3DSA:1.10.287.100 274 309 4.3E-4 T 28-03-2018 SMD44_RS02260 8a5973df16f124da6e39a70ce761996c 730 SUPERFAMILY SSF48208 306 727 3.97E-93 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS02260 8a5973df16f124da6e39a70ce761996c 730 Gene3D G3DSA:2.70.98.50 45 272 5.6E-68 T 28-03-2018 SMD44_RS31800 07bd056eb05c86adc310e2f6a50bb679 64 SUPERFAMILY SSF54862 3 63 7.12E-12 T 28-03-2018 SMD44_RS31800 07bd056eb05c86adc310e2f6a50bb679 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 4.1E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS31800 07bd056eb05c86adc310e2f6a50bb679 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 4.1E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS31800 07bd056eb05c86adc310e2f6a50bb679 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 4.1E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS31800 07bd056eb05c86adc310e2f6a50bb679 64 Gene3D G3DSA:3.30.70.20 1 64 1.0E-7 T 28-03-2018 SMD44_RS31800 07bd056eb05c86adc310e2f6a50bb679 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 61 7.6E-13 T 28-03-2018 SMD44_RS18585 9e5c476775633419c56251e7567f7769 276 Pfam PF01048 Phosphorylase superfamily 78 242 6.5E-16 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS18585 9e5c476775633419c56251e7567f7769 276 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 26 257 3.6E-66 T 28-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 SMD44_RS18585 9e5c476775633419c56251e7567f7769 276 Gene3D G3DSA:3.40.50.1580 12 256 1.1E-52 T 28-03-2018 SMD44_RS18585 9e5c476775633419c56251e7567f7769 276 SUPERFAMILY SSF53167 77 243 1.83E-28 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS18585 9e5c476775633419c56251e7567f7769 276 Hamap MF_00991 Futalosine hydrolase [mqnB]. 39 260 25.751 T 28-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 SMD44_RS08710 ade0e195d7276bb51e5b7329e1cb7657 367 Pfam PF13480 Acetyltransferase (GNAT) domain 161 301 3.5E-38 T 28-03-2018 SMD44_RS08710 ade0e195d7276bb51e5b7329e1cb7657 367 Gene3D G3DSA:3.40.630.30 108 315 1.7E-24 T 28-03-2018 SMD44_RS08710 ade0e195d7276bb51e5b7329e1cb7657 367 SUPERFAMILY SSF55729 156 323 3.26E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS28950 139cbbff96b050384edc5391e9f0d98e 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 1.5E-69 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS28950 139cbbff96b050384edc5391e9f0d98e 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 3.8E-30 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS28950 139cbbff96b050384edc5391e9f0d98e 282 PIRSF PIRSF000105 1 282 1.8E-92 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMD44_RS28950 139cbbff96b050384edc5391e9f0d98e 282 Gene3D G3DSA:3.40.50.720 1 183 1.9E-60 T 28-03-2018 SMD44_RS28950 139cbbff96b050384edc5391e9f0d98e 282 SUPERFAMILY SSF48179 186 281 1.87E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS28950 139cbbff96b050384edc5391e9f0d98e 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS28950 139cbbff96b050384edc5391e9f0d98e 282 SUPERFAMILY SSF51735 3 182 2.07E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS28950 139cbbff96b050384edc5391e9f0d98e 282 Gene3D G3DSA:1.10.1040.10 184 282 4.2E-30 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS39765 997955d62277b92298ff2e570b0036bc 583 SUPERFAMILY SSF55961 429 561 1.76E-5 T 28-03-2018 SMD44_RS39765 997955d62277b92298ff2e570b0036bc 583 Gene3D G3DSA:3.30.530.20 428 577 7.7E-7 T 28-03-2018 IPR023393 START-like domain SMD44_RS39765 997955d62277b92298ff2e570b0036bc 583 Pfam PF00202 Aminotransferase class-III 34 405 1.3E-88 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS39765 997955d62277b92298ff2e570b0036bc 583 SUPERFAMILY SSF53383 34 408 1.08E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS39765 997955d62277b92298ff2e570b0036bc 583 Gene3D G3DSA:3.90.1150.10 298 420 9.6E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS39765 997955d62277b92298ff2e570b0036bc 583 Gene3D G3DSA:3.40.640.10 173 297 4.1E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS39765 997955d62277b92298ff2e570b0036bc 583 Gene3D G3DSA:3.90.1150.10 1 172 5.7E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS25375 7857a6613a91f3d51aa58b6cb56b5573 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.4E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS25375 7857a6613a91f3d51aa58b6cb56b5573 190 Gene3D G3DSA:1.10.10.60 5 60 5.5E-17 T 28-03-2018 SMD44_RS25375 7857a6613a91f3d51aa58b6cb56b5573 190 Gene3D G3DSA:1.10.357.10 61 182 3.2E-7 T 28-03-2018 SMD44_RS25375 7857a6613a91f3d51aa58b6cb56b5573 190 SUPERFAMILY SSF46689 3 74 9.23E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS25375 7857a6613a91f3d51aa58b6cb56b5573 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS25375 7857a6613a91f3d51aa58b6cb56b5573 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 SUPERFAMILY SSF47336 156 224 4.32E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 Gene3D G3DSA:3.30.300.30 46 165 2.7E-43 T 28-03-2018 SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 Pfam PF00550 Phosphopantetheine attachment site 164 224 1.6E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 Pfam PF00501 AMP-binding enzyme 2 51 3.3E-11 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 SMART SM00823 Phosphopantetheine attachment site 162 231 3.4E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 ProSitePatterns PS00012 Phosphopantetheine attachment site. 186 201 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 Gene3D G3DSA:2.30.38.10 1 44 7.5E-10 T 28-03-2018 SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 Pfam PF13193 AMP-binding enzyme C-terminal domain 59 136 4.5E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 SUPERFAMILY SSF56801 1 175 3.14E-56 T 28-03-2018 SMD44_RS39815 f3c845059ed831839abe1373d7f9e646 235 Gene3D G3DSA:1.10.1200.10 166 234 1.9E-25 T 28-03-2018 SMD44_RS40005 2e91698d4108190b8c548e11562a41d0 308 SUPERFAMILY SSF53850 26 237 1.68E-35 T 28-03-2018 SMD44_RS40005 2e91698d4108190b8c548e11562a41d0 308 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 236 6.1E-26 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS40005 2e91698d4108190b8c548e11562a41d0 308 Gene3D G3DSA:3.40.190.10 174 269 2.2E-13 T 28-03-2018 SMD44_RS40005 2e91698d4108190b8c548e11562a41d0 308 Gene3D G3DSA:3.90.76.10 48 173 7.0E-20 T 28-03-2018 SMD44_RS15125 bca76489425abc9c90ac37f6a9767c1b 442 Pfam PF13604 AAA domain 16 171 1.9E-8 T 28-03-2018 SMD44_RS15125 bca76489425abc9c90ac37f6a9767c1b 442 Gene3D G3DSA:3.40.50.300 255 398 3.0E-9 T 28-03-2018 SMD44_RS15125 bca76489425abc9c90ac37f6a9767c1b 442 Gene3D G3DSA:3.40.50.300 7 200 2.3E-18 T 28-03-2018 SMD44_RS15125 bca76489425abc9c90ac37f6a9767c1b 442 SUPERFAMILY SSF52540 282 398 1.54E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15125 bca76489425abc9c90ac37f6a9767c1b 442 SUPERFAMILY SSF52540 25 234 1.54E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 1.2E-228 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 SUPERFAMILY SSF53732 1 465 3.14E-164 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 Gene3D G3DSA:3.40.1060.10 155 288 1.4E-45 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 59.414 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 Gene3D G3DSA:3.30.499.10 325 473 1.5E-50 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 108 116 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 195 208 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 399 412 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 119 132 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 343 354 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 82 95 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 133 148 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 209 222 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 PRINTS PR00415 Aconitase family signature 286 300 5.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 3.2E-155 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30245 79c0d1dd2d6d0659d7c583f511b39348 474 Gene3D G3DSA:3.30.499.10 1 154 1.4E-40 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 SUPERFAMILY SSF55257 14 48 2.35E-24 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 SUPERFAMILY SSF55257 170 220 2.35E-24 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 Gene3D G3DSA:1.10.150.20 239 322 3.8E-25 T 28-03-2018 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.187 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 SMART SM00662 18 225 1.3E-94 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 6.0E-24 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.4E-19 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 5.4E-115 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 311 4.0E-23 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 SUPERFAMILY SSF56553 48 169 4.97E-42 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 SUPERFAMILY SSF47789 247 318 3.4E-23 T 28-03-2018 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 Gene3D G3DSA:3.30.1360.10 106 221 2.0E-27 T 28-03-2018 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 Gene3D G3DSA:3.30.1360.10 3 83 3.4E-17 T 28-03-2018 SMD44_RS25640 2a8c902dd7b34eda6323416da5b1f929 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 1.8E-25 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 Pfam PF00344 SecY translocase 73 420 1.3E-116 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 436 29.353 T 28-03-2018 IPR026593 Protein translocase subunit SecY SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 432 1.9E-150 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 405 423 2.6E-107 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 Gene3D G3DSA:1.10.3370.10 1 437 4.4E-162 T 28-03-2018 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 PIRSF PIRSF004557 1 437 2.2E-125 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 SUPERFAMILY SSF103491 2 427 6.93E-126 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS25605 06e65330857c797dba0fdc92125533e6 437 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS32800 94e1c733ee871d9572eea3e60d081d48 268 Gene3D G3DSA:3.40.50.1400 117 227 1.1E-20 T 28-03-2018 SMD44_RS32800 94e1c733ee871d9572eea3e60d081d48 268 SUPERFAMILY SSF53800 9 239 2.62E-41 T 28-03-2018 SMD44_RS32800 94e1c733ee871d9572eea3e60d081d48 268 Pfam PF01903 CbiX 139 233 1.5E-10 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMD44_RS32800 94e1c733ee871d9572eea3e60d081d48 268 Pfam PF01903 CbiX 14 115 8.7E-23 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMD44_RS32800 94e1c733ee871d9572eea3e60d081d48 268 Gene3D G3DSA:3.40.50.1400 1 116 1.6E-29 T 28-03-2018 SMD44_RS22915 2cad6bd48b566c529b4e3f9ca2105c6d 96 Gene3D G3DSA:1.10.357.10 2 96 1.2E-11 T 28-03-2018 SMD44_RS22915 2cad6bd48b566c529b4e3f9ca2105c6d 96 Pfam PF13305 WHG domain 20 73 5.6E-7 T 28-03-2018 IPR025996 WHG domain SMD44_RS22915 2cad6bd48b566c529b4e3f9ca2105c6d 96 SUPERFAMILY SSF48498 5 79 1.81E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS08890 fe121b2fdc4d7e4ed04e3d78d174deb4 590 Gene3D G3DSA:3.10.105.10 359 558 1.9E-29 T 28-03-2018 SMD44_RS08890 fe121b2fdc4d7e4ed04e3d78d174deb4 590 Gene3D G3DSA:3.90.76.10 101 220 2.2E-21 T 28-03-2018 SMD44_RS08890 fe121b2fdc4d7e4ed04e3d78d174deb4 590 SUPERFAMILY SSF53850 64 588 6.7E-74 T 28-03-2018 SMD44_RS08890 fe121b2fdc4d7e4ed04e3d78d174deb4 590 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 113 496 1.8E-53 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS08890 fe121b2fdc4d7e4ed04e3d78d174deb4 590 Gene3D G3DSA:3.40.190.10 221 358 2.1E-17 T 28-03-2018 SMD44_RS08890 fe121b2fdc4d7e4ed04e3d78d174deb4 590 PIRSF PIRSF002741 41 590 1.3E-43 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS08005 f2b9d9da8b2b7b0d65ffa3dd5feb5b42 377 Pfam PF03595 Voltage-dependent anion channel 29 364 8.4E-66 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 SUPERFAMILY SSF55781 322 453 1.2E-12 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 Gene3D G3DSA:3.30.450.20 18 236 6.2E-11 T 28-03-2018 SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 SUPERFAMILY SSF81606 489 693 1.57E-12 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 SUPERFAMILY SSF55874 734 817 3.47E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 Gene3D G3DSA:3.60.40.10 452 695 1.8E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 501 692 2.6E-52 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 SUPERFAMILY SSF55785 20 64 4.19E-9 T 28-03-2018 IPR000014 PAS domain SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 Gene3D G3DSA:3.30.450.40 258 451 7.3E-24 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 Gene3D G3DSA:3.30.565.10 696 822 3.7E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 SMART SM00331 472 692 5.3E-54 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS34250 fb1219c54516fbc2e9b820dbfd66a7ce 822 Pfam PF00989 PAS fold 23 61 1.6E-5 T 28-03-2018 IPR013767 PAS fold GO:0006355 SMD44_RS00265 22fdd5972e67821e2d3b0c5baef222ba 241 Pfam PF00805 Pentapeptide repeats (8 copies) 133 166 9.3E-12 T 28-03-2018 IPR001646 Pentapeptide repeat SMD44_RS00265 22fdd5972e67821e2d3b0c5baef222ba 241 Pfam PF00805 Pentapeptide repeats (8 copies) 192 227 2.9E-7 T 28-03-2018 IPR001646 Pentapeptide repeat SMD44_RS00265 22fdd5972e67821e2d3b0c5baef222ba 241 Gene3D G3DSA:2.160.10.20 90 173 4.6E-16 T 28-03-2018 SMD44_RS00265 22fdd5972e67821e2d3b0c5baef222ba 241 Gene3D G3DSA:2.160.10.20 174 240 1.7E-14 T 28-03-2018 SMD44_RS00265 22fdd5972e67821e2d3b0c5baef222ba 241 SUPERFAMILY SSF141571 111 227 6.67E-29 T 28-03-2018 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 SUPERFAMILY SSF52374 2 328 7.5E-81 T 28-03-2018 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 328 2.0E-94 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 329 36.901 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 8.0E-22 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 197 207 8.0E-22 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 144 165 8.0E-22 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 8.0E-22 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 Gene3D G3DSA:1.10.240.10 193 311 5.1E-30 T 28-03-2018 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 Pfam PF00579 tRNA synthetases class I (W and Y) 3 283 1.2E-68 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS24055 8a6f515cfa0666d1d7a3c4c20784a128 345 Gene3D G3DSA:3.40.50.620 1 192 4.6E-63 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 Gene3D G3DSA:1.10.10.10 138 222 2.8E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 Gene3D G3DSA:3.40.50.2300 4 137 4.1E-38 T 28-03-2018 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 Pfam PF00072 Response regulator receiver domain 7 117 4.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 SMART SM00421 160 217 2.9E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 4.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 4.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 4.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 SUPERFAMILY SSF46894 152 223 1.36E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 SUPERFAMILY SSF52172 4 137 3.27E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 217 1.6E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22640 8a4339414ed0c53543ea2fc7d6bf23d3 226 SMART SM00448 5 119 3.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS40525 f8878e5abd2f421adfe276ba30606d09 253 Gene3D G3DSA:2.60.40.10 143 250 0.0041 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 4.1E-154 T 28-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 Gene3D G3DSA:3.30.160.20 225 307 1.7E-32 T 28-03-2018 SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 SUPERFAMILY SSF75620 29 366 7.46E-121 T 28-03-2018 SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 Gene3D G3DSA:1.20.58.410 2 115 5.3E-31 T 28-03-2018 SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 SMART SM00937 84 194 3.8E-45 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 Pfam PF03462 PCRF domain 30 219 9.5E-57 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 37.959 T 28-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 SMD44_RS16070 e13824e39c01a8d8771ac79627f42946 368 Pfam PF00472 RF-1 domain 229 336 6.4E-38 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD44_RS17285 b38ee767e75b2e66284e1527a52bf590 207 Gene3D G3DSA:3.40.630.30 1 207 2.0E-35 T 28-03-2018 SMD44_RS17285 b38ee767e75b2e66284e1527a52bf590 207 SUPERFAMILY SSF55729 9 185 8.77E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS17285 b38ee767e75b2e66284e1527a52bf590 207 Pfam PF13302 Acetyltransferase (GNAT) domain 15 162 3.4E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS08325 cff557d2ea1a6f2aad5e7eb0d1c028c0 353 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 326 2.6E-114 T 28-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c SMD44_RS08325 cff557d2ea1a6f2aad5e7eb0d1c028c0 353 Gene3D G3DSA:3.20.20.30 1 347 3.8E-69 T 28-03-2018 SMD44_RS08325 cff557d2ea1a6f2aad5e7eb0d1c028c0 353 Pfam PF00296 Luciferase-like monooxygenase 17 322 3.5E-77 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS08325 cff557d2ea1a6f2aad5e7eb0d1c028c0 353 SUPERFAMILY SSF51679 1 342 1.02E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS33660 bde4b4c8f5a205ebb6c5d6cee1cc7770 508 Pfam PF13520 Amino acid permease 41 475 1.3E-60 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS33660 bde4b4c8f5a205ebb6c5d6cee1cc7770 508 ProSitePatterns PS00218 Amino acid permeases signature. 67 98 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD44_RS33660 bde4b4c8f5a205ebb6c5d6cee1cc7770 508 PIRSF PIRSF006060 22 505 4.6E-61 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS01945 54adb6c6a99accdb48d04c9763815202 344 Gene3D G3DSA:3.40.47.10 165 338 8.8E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01945 54adb6c6a99accdb48d04c9763815202 344 Gene3D G3DSA:3.40.47.10 1 164 2.4E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01945 54adb6c6a99accdb48d04c9763815202 344 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 190 3.5E-26 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01945 54adb6c6a99accdb48d04c9763815202 344 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 331 7.6E-32 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01945 54adb6c6a99accdb48d04c9763815202 344 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 7 331 59.841 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01945 54adb6c6a99accdb48d04c9763815202 344 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 9 330 1.7E-95 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01945 54adb6c6a99accdb48d04c9763815202 344 SUPERFAMILY SSF53901 10 332 1.14E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS25840 fb49f2edf43d7a8665a2e37c43bb3a3f 789 Pfam PF00069 Protein kinase domain 23 270 4.2E-44 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25840 fb49f2edf43d7a8665a2e37c43bb3a3f 789 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 146 158 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS25840 fb49f2edf43d7a8665a2e37c43bb3a3f 789 Gene3D G3DSA:3.40.1000.10 656 788 2.5E-18 T 28-03-2018 SMD44_RS25840 fb49f2edf43d7a8665a2e37c43bb3a3f 789 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 29 52 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS25840 fb49f2edf43d7a8665a2e37c43bb3a3f 789 SMART SM00220 23 282 3.9E-50 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25840 fb49f2edf43d7a8665a2e37c43bb3a3f 789 Gene3D G3DSA:1.10.510.10 109 341 3.1E-41 T 28-03-2018 SMD44_RS25840 fb49f2edf43d7a8665a2e37c43bb3a3f 789 Gene3D G3DSA:3.30.200.20 1 108 6.2E-22 T 28-03-2018 SMD44_RS25840 fb49f2edf43d7a8665a2e37c43bb3a3f 789 SUPERFAMILY SSF56112 18 278 3.1E-64 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS21505 a775394da9ce22910c5617b1cb938c7a 274 SUPERFAMILY SSF51621 2 273 3.54E-72 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS21505 a775394da9ce22910c5617b1cb938c7a 274 Gene3D G3DSA:3.20.20.60 1 274 3.3E-67 T 28-03-2018 SMD44_RS21505 a775394da9ce22910c5617b1cb938c7a 274 Pfam PF13714 Phosphoenolpyruvate phosphomutase 3 241 6.3E-65 T 28-03-2018 SMD44_RS10945 3d12c51c73ea778135a62af791d0b930 363 SUPERFAMILY SSF50182 177 242 1.01E-15 T 28-03-2018 IPR010920 LSM domain SMD44_RS10945 3d12c51c73ea778135a62af791d0b930 363 Pfam PF00924 Mechanosensitive ion channel 136 329 1.8E-30 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMD44_RS10945 3d12c51c73ea778135a62af791d0b930 363 Gene3D G3DSA:2.30.30.60 193 243 2.3E-13 T 28-03-2018 SMD44_RS27600 3fc89bd0caf900264c19cb79d6905964 168 SMART SM00347 45 148 5.6E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27600 3fc89bd0caf900264c19cb79d6905964 168 SUPERFAMILY SSF46785 21 160 9.52E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27600 3fc89bd0caf900264c19cb79d6905964 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS27600 3fc89bd0caf900264c19cb79d6905964 168 Gene3D G3DSA:1.10.10.10 1 166 6.3E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27600 3fc89bd0caf900264c19cb79d6905964 168 Pfam PF12802 MarR family 51 111 1.6E-11 T 28-03-2018 SMD44_RS27600 3fc89bd0caf900264c19cb79d6905964 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 2.7E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27600 3fc89bd0caf900264c19cb79d6905964 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 2.7E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27600 3fc89bd0caf900264c19cb79d6905964 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 2.7E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27955 8137543c7e1daf63ed22c1b5a4cb14ce 529 SMART SM00490 240 321 2.1E-32 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS27955 8137543c7e1daf63ed22c1b5a4cb14ce 529 Pfam PF00270 DEAD/DEAH box helicase 2 169 4.0E-48 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS27955 8137543c7e1daf63ed22c1b5a4cb14ce 529 Gene3D G3DSA:3.40.50.300 204 528 9.1E-50 T 28-03-2018 SMD44_RS27955 8137543c7e1daf63ed22c1b5a4cb14ce 529 Pfam PF00271 Helicase conserved C-terminal domain 212 321 4.5E-29 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS27955 8137543c7e1daf63ed22c1b5a4cb14ce 529 SUPERFAMILY SSF52540 54 341 1.0E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27955 8137543c7e1daf63ed22c1b5a4cb14ce 529 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 132 140 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site SMD44_RS27955 8137543c7e1daf63ed22c1b5a4cb14ce 529 Gene3D G3DSA:3.40.50.300 1 203 6.2E-52 T 28-03-2018 SMD44_RS27955 8137543c7e1daf63ed22c1b5a4cb14ce 529 SMART SM00487 1 204 1.1E-42 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS36110 1db66606d137719cf102d260d807b9cd 214 SUPERFAMILY SSF50475 13 192 1.61E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS36110 1db66606d137719cf102d260d807b9cd 214 Gene3D G3DSA:2.30.110.10 1 213 5.4E-50 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS36110 1db66606d137719cf102d260d807b9cd 214 Pfam PF04299 Putative FMN-binding domain 1 171 3.9E-38 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type SMD44_RS36110 1db66606d137719cf102d260d807b9cd 214 PIRSF PIRSF010372 1 214 9.3E-40 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type SMD44_RS10550 76c2f3160d1565a71b479c87e2abfd6f 238 SUPERFAMILY SSF52540 3 236 3.11E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10550 76c2f3160d1565a71b479c87e2abfd6f 238 Pfam PF00005 ABC transporter 21 165 6.0E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS10550 76c2f3160d1565a71b479c87e2abfd6f 238 PIRSF PIRSF039137 1 238 2.1E-112 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 SMD44_RS10550 76c2f3160d1565a71b479c87e2abfd6f 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS10550 76c2f3160d1565a71b479c87e2abfd6f 238 SMART SM00382 29 216 4.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS10550 76c2f3160d1565a71b479c87e2abfd6f 238 Gene3D G3DSA:3.40.50.300 1 237 4.9E-58 T 28-03-2018 SMD44_RS05735 0e57d31b1d692dc377739d5297d78636 229 Gene3D G3DSA:3.40.50.300 28 225 1.3E-17 T 28-03-2018 SMD44_RS05735 0e57d31b1d692dc377739d5297d78636 229 SUPERFAMILY SSF52540 21 225 1.03E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS05735 0e57d31b1d692dc377739d5297d78636 229 Hamap MF_01389 Urease accessory protein UreG [ureG]. 25 223 43.269 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 SMD44_RS05735 0e57d31b1d692dc377739d5297d78636 229 PIRSF PIRSF005624 8 229 4.8E-47 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 SMD44_RS05735 0e57d31b1d692dc377739d5297d78636 229 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 27 219 1.3E-82 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 SMD44_RS05735 0e57d31b1d692dc377739d5297d78636 229 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 29 199 3.4E-35 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 483 6.8E-144 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 Gene3D G3DSA:3.40.50.620 5 124 4.1E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 Gene3D G3DSA:1.10.1160.10 251 334 3.3E-28 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 SUPERFAMILY SSF48163 319 485 1.06E-34 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 Gene3D G3DSA:3.40.50.620 125 250 3.8E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 322 2.6E-89 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 3.0E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 209 217 3.0E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 3.0E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 3.0E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 193 203 3.0E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 485 31.683 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 Gene3D G3DSA:1.10.8.70 338 384 0.0022 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 Gene3D G3DSA:1.10.10.350 390 490 3.4E-24 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD44_RS30205 b8d96ddf7226dc9d05b18147d62d8811 490 SUPERFAMILY SSF52374 5 318 1.02E-103 T 28-03-2018 SMD44_RS09970 140c075aabe96f0f019c3f93fcee123a 296 Pfam PF01638 HxlR-like helix-turn-helix 20 105 6.8E-25 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS09970 140c075aabe96f0f019c3f93fcee123a 296 SUPERFAMILY SSF52833 129 291 3.16E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS09970 140c075aabe96f0f019c3f93fcee123a 296 SUPERFAMILY SSF46785 6 112 2.56E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09970 140c075aabe96f0f019c3f93fcee123a 296 Pfam PF08534 Redoxin 180 278 1.3E-13 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SMD44_RS09970 140c075aabe96f0f019c3f93fcee123a 296 Gene3D G3DSA:3.40.30.10 113 293 3.4E-22 T 28-03-2018 SMD44_RS09970 140c075aabe96f0f019c3f93fcee123a 296 Gene3D G3DSA:1.10.10.10 2 112 9.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14390 d99df6178cd79b52d6df23b65162625b 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 262 3.5E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS14390 d99df6178cd79b52d6df23b65162625b 283 SUPERFAMILY SSF161098 82 259 1.83E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS14390 d99df6178cd79b52d6df23b65162625b 283 Gene3D G3DSA:1.10.3720.10 77 272 4.2E-22 T 28-03-2018 SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1057 1311 1.3E-36 T 28-03-2018 SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 SUPERFAMILY SSF52980 1086 1228 1.34E-6 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 Gene3D G3DSA:3.40.50.300 356 499 2.7E-11 T 28-03-2018 SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 Gene3D G3DSA:3.40.50.300 709 976 1.2E-37 T 28-03-2018 SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 Gene3D G3DSA:3.40.50.300 37 332 1.2E-53 T 28-03-2018 SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 Pfam PF00580 UvrD/REP helicase N-terminal domain 42 321 1.0E-51 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 SUPERFAMILY SSF52540 701 971 9.75E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 SUPERFAMILY SSF52540 39 464 4.35E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 Pfam PF13361 UvrD-like helicase C-terminal domain 822 952 5.7E-20 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD44_RS28065 f4d7ec3a8788b73cd8d1637224b04da3 1322 Gene3D G3DSA:3.90.320.10 977 1261 7.3E-17 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMD44_RS07050 bbca6efec8d178fbba8691cb3e0006a5 412 Gene3D G3DSA:1.20.1250.20 206 387 2.8E-14 T 28-03-2018 SMD44_RS07050 bbca6efec8d178fbba8691cb3e0006a5 412 SUPERFAMILY SSF103473 7 385 7.19E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS07050 bbca6efec8d178fbba8691cb3e0006a5 412 Gene3D G3DSA:1.20.1250.20 11 202 3.9E-21 T 28-03-2018 SMD44_RS07050 bbca6efec8d178fbba8691cb3e0006a5 412 Pfam PF07690 Major Facilitator Superfamily 23 247 5.1E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 374 7.4E-33 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 2.6E-171 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 447 2.5E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Gene3D G3DSA:3.40.120.10 2 148 1.7E-43 T 28-03-2018 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 SUPERFAMILY SSF53738 163 260 1.41E-25 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 SUPERFAMILY SSF53738 263 370 1.22E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 44.001 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 8.7E-38 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Gene3D G3DSA:3.40.120.10 276 379 1.5E-32 T 28-03-2018 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 SUPERFAMILY SSF53738 4 185 5.49E-44 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Gene3D G3DSA:3.30.310.50 380 452 1.2E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 4.6E-10 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 4.6E-10 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 4.6E-10 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 SUPERFAMILY SSF55957 364 452 8.11E-23 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 259 1.1E-16 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS25675 d6a41d16dd9e2e518b82860e84939047 452 Gene3D G3DSA:3.40.120.10 162 275 1.5E-28 T 28-03-2018 SMD44_RS28500 27d95a9f59ed1409061fd0993fd63b11 153 Gene3D G3DSA:2.10.109.10 4 111 2.6E-19 T 28-03-2018 SMD44_RS28500 27d95a9f59ed1409061fd0993fd63b11 153 SUPERFAMILY SSF51306 15 114 1.23E-21 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS28500 27d95a9f59ed1409061fd0993fd63b11 153 Pfam PF00717 Peptidase S24-like 19 81 5.1E-12 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS28500 27d95a9f59ed1409061fd0993fd63b11 153 TIGRFAM TIGR02754 sod_Ni_protease: nickel-type superoxide dismutase maturation protease 19 103 1.1E-22 T 28-03-2018 IPR014124 Peptidase S26A, superoxide dismutase maturation protease, nickel-type SMD44_RS35510 87cc10224ab021989a0fa41f259b72ac 316 SUPERFAMILY SSF48576 18 302 1.04E-73 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS35510 87cc10224ab021989a0fa41f259b72ac 316 Pfam PF00494 Squalene/phytoene synthase 28 289 1.0E-71 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMD44_RS35510 87cc10224ab021989a0fa41f259b72ac 316 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 176 201 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SMD44_RS35510 87cc10224ab021989a0fa41f259b72ac 316 Gene3D G3DSA:1.10.600.10 6 304 3.2E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS35510 87cc10224ab021989a0fa41f259b72ac 316 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 141 156 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SMD44_RS35510 87cc10224ab021989a0fa41f259b72ac 316 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 26 298 3.5E-94 T 28-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 SMD44_RS17160 a854d910f2807ce3b3b2b3f0f02797a7 262 Pfam PF01381 Helix-turn-helix 21 54 1.4E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS17160 a854d910f2807ce3b3b2b3f0f02797a7 262 Gene3D G3DSA:1.10.260.40 8 91 2.7E-10 T 28-03-2018 SMD44_RS17160 a854d910f2807ce3b3b2b3f0f02797a7 262 SMART SM00530 20 74 1.1E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS17160 a854d910f2807ce3b3b2b3f0f02797a7 262 SUPERFAMILY SSF47413 14 68 1.41E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS39595 b4c83e5c22eb05bd409655e52c5af831 424 TIGRFAM TIGR04516 glycosyl_450act: glycosyltransferase, activator-dependent family 1 422 5.8E-137 T 28-03-2018 IPR030953 Glycosyltransferase, activator-dependent family GO:0016757 SMD44_RS39595 b4c83e5c22eb05bd409655e52c5af831 424 Pfam PF06722 Protein of unknown function (DUF1205) 209 306 2.0E-18 T 28-03-2018 IPR010610 Domain of unknown function DUF1205 SMD44_RS39595 b4c83e5c22eb05bd409655e52c5af831 424 Gene3D G3DSA:3.40.50.2000 1 237 8.6E-30 T 28-03-2018 SMD44_RS39595 b4c83e5c22eb05bd409655e52c5af831 424 SUPERFAMILY SSF53756 97 422 8.57E-68 T 28-03-2018 SMD44_RS39595 b4c83e5c22eb05bd409655e52c5af831 424 SUPERFAMILY SSF53756 1 67 8.57E-68 T 28-03-2018 SMD44_RS39595 b4c83e5c22eb05bd409655e52c5af831 424 Gene3D G3DSA:3.40.50.2000 238 403 2.6E-28 T 28-03-2018 SMD44_RS04105 8768291a41db37103fb5391ae88c0e80 242 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 129 1.1E-21 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS04105 8768291a41db37103fb5391ae88c0e80 242 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 220 7.5E-27 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS04105 8768291a41db37103fb5391ae88c0e80 242 Pfam PF07398 MDMPI C-terminal domain 144 234 2.0E-13 T 28-03-2018 IPR010872 MDMPI C-terminal SMD44_RS04105 8768291a41db37103fb5391ae88c0e80 242 SUPERFAMILY SSF109854 8 130 2.52E-11 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS04105 8768291a41db37103fb5391ae88c0e80 242 Gene3D G3DSA:1.20.120.450 1 128 1.4E-19 T 28-03-2018 SMD44_RS04105 8768291a41db37103fb5391ae88c0e80 242 Gene3D G3DSA:3.30.1050.10 129 226 8.0E-6 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS10220 28fac23015377c31cc3ad179f94a7bd5 422 Gene3D G3DSA:1.20.1250.20 3 211 8.7E-24 T 28-03-2018 SMD44_RS10220 28fac23015377c31cc3ad179f94a7bd5 422 Pfam PF07690 Major Facilitator Superfamily 272 414 1.1E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS10220 28fac23015377c31cc3ad179f94a7bd5 422 Pfam PF00083 Sugar (and other) transporter 7 211 1.2E-24 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD44_RS10220 28fac23015377c31cc3ad179f94a7bd5 422 Gene3D G3DSA:1.20.1250.20 212 418 1.8E-21 T 28-03-2018 SMD44_RS10220 28fac23015377c31cc3ad179f94a7bd5 422 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS10220 28fac23015377c31cc3ad179f94a7bd5 422 SUPERFAMILY SSF103473 3 415 1.7E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17535 4f1a63719974cf08db1f33e13ef36f82 198 Pfam PF01323 DSBA-like thioredoxin domain 4 182 9.6E-32 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD44_RS17535 4f1a63719974cf08db1f33e13ef36f82 198 SUPERFAMILY SSF52833 4 196 2.93E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS17535 4f1a63719974cf08db1f33e13ef36f82 198 Gene3D G3DSA:3.40.30.10 1 198 4.0E-40 T 28-03-2018 SMD44_RS05830 bd0f6d75d77c9237e1617bd7da3f8054 439 Gene3D G3DSA:3.90.1150.10 327 437 2.6E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS05830 bd0f6d75d77c9237e1617bd7da3f8054 439 Gene3D G3DSA:3.40.640.10 62 326 6.7E-75 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS05830 bd0f6d75d77c9237e1617bd7da3f8054 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS05830 bd0f6d75d77c9237e1617bd7da3f8054 439 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 23 431 7.2E-165 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SMD44_RS05830 bd0f6d75d77c9237e1617bd7da3f8054 439 SUPERFAMILY SSF53383 15 430 3.73E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS05830 bd0f6d75d77c9237e1617bd7da3f8054 439 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 11 434 48.662 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SMD44_RS05830 bd0f6d75d77c9237e1617bd7da3f8054 439 Pfam PF00202 Aminotransferase class-III 34 422 1.7E-116 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS16670 f482f137bf545a097f8bddcd8154601f 138 SUPERFAMILY SSF103196 9 121 8.02E-21 T 28-03-2018 SMD44_RS16670 f482f137bf545a097f8bddcd8154601f 138 Gene3D G3DSA:3.30.450.30 4 125 1.6E-20 T 28-03-2018 SMD44_RS16670 f482f137bf545a097f8bddcd8154601f 138 Pfam PF03259 Roadblock/LC7 domain 10 96 8.1E-16 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS16670 f482f137bf545a097f8bddcd8154601f 138 SMART SM00960 8 96 4.3E-16 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS22680 1562a24c58c6ba6a3e84558dfdd067ed 647 SMART SM00220 17 277 6.1E-40 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS22680 1562a24c58c6ba6a3e84558dfdd067ed 647 Gene3D G3DSA:3.30.200.20 12 98 9.7E-11 T 28-03-2018 SMD44_RS22680 1562a24c58c6ba6a3e84558dfdd067ed 647 Gene3D G3DSA:1.10.510.10 99 294 7.8E-41 T 28-03-2018 SMD44_RS22680 1562a24c58c6ba6a3e84558dfdd067ed 647 SUPERFAMILY SSF56112 369 430 1.04E-58 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS22680 1562a24c58c6ba6a3e84558dfdd067ed 647 SUPERFAMILY SSF56112 15 274 1.04E-58 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS22680 1562a24c58c6ba6a3e84558dfdd067ed 647 Pfam PF00069 Protein kinase domain 17 269 7.8E-39 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS22680 1562a24c58c6ba6a3e84558dfdd067ed 647 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 45 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS22680 1562a24c58c6ba6a3e84558dfdd067ed 647 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS23480 2d1cb75b1790c78c0a42f68954e4b328 304 Gene3D G3DSA:3.40.50.1820 6 304 1.6E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23480 2d1cb75b1790c78c0a42f68954e4b328 304 PRINTS PR00412 Epoxide hydrolase signature 47 65 3.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23480 2d1cb75b1790c78c0a42f68954e4b328 304 PRINTS PR00412 Epoxide hydrolase signature 279 301 3.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23480 2d1cb75b1790c78c0a42f68954e4b328 304 PRINTS PR00412 Epoxide hydrolase signature 115 128 3.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23480 2d1cb75b1790c78c0a42f68954e4b328 304 PRINTS PR00412 Epoxide hydrolase signature 129 142 3.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23480 2d1cb75b1790c78c0a42f68954e4b328 304 SUPERFAMILY SSF53474 10 304 1.02E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23480 2d1cb75b1790c78c0a42f68954e4b328 304 Pfam PF00561 alpha/beta hydrolase fold 41 152 1.9E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS01700 88c5737fcb0d1615dca043093a34b29c 624 Gene3D G3DSA:3.40.50.300 351 612 7.4E-65 T 28-03-2018 SMD44_RS01700 88c5737fcb0d1615dca043093a34b29c 624 Pfam PF00005 ABC transporter 371 534 1.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS01700 88c5737fcb0d1615dca043093a34b29c 624 Gene3D G3DSA:1.20.1560.10 144 327 3.8E-13 T 28-03-2018 SMD44_RS01700 88c5737fcb0d1615dca043093a34b29c 624 SUPERFAMILY SSF90123 31 315 8.37E-20 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS01700 88c5737fcb0d1615dca043093a34b29c 624 Gene3D G3DSA:1.20.1560.10 8 117 0.0016 T 28-03-2018 SMD44_RS01700 88c5737fcb0d1615dca043093a34b29c 624 SUPERFAMILY SSF52540 346 605 1.36E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS01700 88c5737fcb0d1615dca043093a34b29c 624 ProSitePatterns PS00211 ABC transporters family signature. 506 520 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS01700 88c5737fcb0d1615dca043093a34b29c 624 SMART SM00382 380 587 1.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Gene3D G3DSA:1.10.510.10 95 302 1.4E-50 T 28-03-2018 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Gene3D G3DSA:2.40.10.120 454 472 4.5E-9 T 28-03-2018 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Gene3D G3DSA:2.40.10.120 374 392 0.0029 T 28-03-2018 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 PRINTS PR00320 G protein beta WD-40 repeat signature 333 347 4.2E-6 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 PRINTS PR00320 G protein beta WD-40 repeat signature 586 600 4.2E-6 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 PRINTS PR00320 G protein beta WD-40 repeat signature 418 432 4.2E-6 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SUPERFAMILY SSF50998 307 602 2.24E-75 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Gene3D G3DSA:2.130.10.10 537 604 3.9E-26 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Gene3D G3DSA:2.130.10.10 310 373 5.2E-18 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SUPERFAMILY SSF56112 6 287 1.97E-75 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 42 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Gene3D G3DSA:2.140.10.10 473 536 2.9E-16 T 28-03-2018 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Gene3D G3DSA:2.140.10.10 393 453 1.5E-16 T 28-03-2018 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Pfam PF00400 WD domain, G-beta repeat 522 557 2.0E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Pfam PF00400 WD domain, G-beta repeat 566 599 9.1E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Pfam PF00400 WD domain, G-beta repeat 447 473 0.13 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Pfam PF00400 WD domain, G-beta repeat 399 431 6.3E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Pfam PF00400 WD domain, G-beta repeat 366 386 0.12 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Pfam PF00400 WD domain, G-beta repeat 312 346 1.9E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Pfam PF00069 Protein kinase domain 12 265 3.8E-47 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 586 600 - T 28-03-2018 IPR019775 WD40 repeat, conserved site SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SMART SM00220 12 270 9.9E-68 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SMART SM00320 518 557 4.6E-9 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SMART SM00320 434 473 0.0032 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SMART SM00320 352 387 1.8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SMART SM00320 560 599 6.4E-10 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SMART SM00320 307 346 1.1E-10 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 SMART SM00320 392 431 2.5E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS29345 fc2af51f31976e67e1bb638fbf57012d 604 Gene3D G3DSA:3.30.200.20 3 94 3.3E-21 T 28-03-2018 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 SMART SM01016 9 89 3.8E-23 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 SUPERFAMILY SSF52374 113 464 5.63E-79 T 28-03-2018 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 Gene3D G3DSA:1.10.730.10 453 587 3.1E-39 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 Pfam PF00750 tRNA synthetases class I (R) 117 457 2.1E-97 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 587 25.616 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 SUPERFAMILY SSF47323 466 587 1.11E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 313 334 4.4E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 118 133 4.4E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 133 149 4.4E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 157 170 4.4E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 Pfam PF05746 DALR anticodon binding domain 472 587 1.0E-31 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 SMART SM00836 472 587 9.3E-36 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 12 587 2.6E-127 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 Gene3D G3DSA:3.40.50.620 111 452 1.3E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 126 137 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 88 7.2E-17 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 SUPERFAMILY SSF55190 6 109 6.93E-17 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS24195 01df72be1b96d8c48ebf945478c68c32 587 Gene3D G3DSA:3.30.1360.70 2 109 2.1E-23 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 195 206 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 449 459 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 Pfam PF00082 Subtilase family 192 487 2.1E-46 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 Gene3D G3DSA:3.40.50.200 150 528 2.0E-69 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 242 252 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 PRINTS PR00723 Subtilisin serine protease family (S8) signature 448 464 3.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 PRINTS PR00723 Subtilisin serine protease family (S8) signature 190 209 3.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 PRINTS PR00723 Subtilisin serine protease family (S8) signature 238 251 3.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 SUPERFAMILY SSF52743 377 527 1.44E-69 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS09425 d8f0ccdd5fc96b61a937dab3eeddb1f4 528 SUPERFAMILY SSF52743 170 350 1.44E-69 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS39925 ff6a2dac9ef146102d6793d5f8e81c34 406 SUPERFAMILY SSF51905 271 346 1.4E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS39925 ff6a2dac9ef146102d6793d5f8e81c34 406 SUPERFAMILY SSF51905 2 169 1.4E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS39925 ff6a2dac9ef146102d6793d5f8e81c34 406 Pfam PF01494 FAD binding domain 3 319 1.8E-21 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS39925 ff6a2dac9ef146102d6793d5f8e81c34 406 Gene3D G3DSA:3.50.50.60 2 355 6.5E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS39925 ff6a2dac9ef146102d6793d5f8e81c34 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 2.8E-17 T 28-03-2018 SMD44_RS39925 ff6a2dac9ef146102d6793d5f8e81c34 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 2.8E-17 T 28-03-2018 SMD44_RS39925 ff6a2dac9ef146102d6793d5f8e81c34 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 2.8E-17 T 28-03-2018 SMD44_RS39925 ff6a2dac9ef146102d6793d5f8e81c34 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.8E-17 T 28-03-2018 SMD44_RS42445 cecace18f33b056072119dc419a046bd 375 Pfam PF00534 Glycosyl transferases group 1 173 334 2.9E-24 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS42445 cecace18f33b056072119dc419a046bd 375 SUPERFAMILY SSF53756 15 355 7.85E-50 T 28-03-2018 SMD44_RS42445 cecace18f33b056072119dc419a046bd 375 Gene3D G3DSA:3.40.50.2000 167 344 1.4E-33 T 28-03-2018 SMD44_RS31970 2539874f6e37d7d0876b91cca7f2d366 254 Pfam PF13359 DDE superfamily endonuclease 102 247 4.7E-29 T 28-03-2018 IPR027806 Harbinger transposase-derived nuclease domain SMD44_RS31970 2539874f6e37d7d0876b91cca7f2d366 254 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 81 2.6E-14 T 28-03-2018 IPR027805 Transposase, Helix-turn-helix domain SMD44_RS00030 2539874f6e37d7d0876b91cca7f2d366 254 Pfam PF13359 DDE superfamily endonuclease 102 247 4.7E-29 T 28-03-2018 IPR027806 Harbinger transposase-derived nuclease domain SMD44_RS00030 2539874f6e37d7d0876b91cca7f2d366 254 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 81 2.6E-14 T 28-03-2018 IPR027805 Transposase, Helix-turn-helix domain SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 SMART SM00636 276 546 2.0E-7 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 ProSitePatterns PS01095 Chitinases family 18 active site. 383 391 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 Gene3D G3DSA:2.60.120.260 32 176 3.6E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 SMART SM00060 182 252 4.6E-13 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 Pfam PF00041 Fibronectin type III domain 185 255 1.8E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 PRINTS PR00014 Fibronectin type III repeat signature 196 205 8.2E-5 T 28-03-2018 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 PRINTS PR00014 Fibronectin type III repeat signature 221 239 8.2E-5 T 28-03-2018 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 PRINTS PR00014 Fibronectin type III repeat signature 239 253 8.2E-5 T 28-03-2018 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 SUPERFAMILY SSF49265 179 264 7.22E-18 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 SUPERFAMILY SSF51445 273 552 1.81E-54 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 SUPERFAMILY SSF49785 37 170 2.76E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 Pfam PF00704 Glycosyl hydrolases family 18 278 553 1.6E-30 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 Gene3D G3DSA:3.20.20.80 272 564 7.6E-48 T 28-03-2018 SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 Gene3D G3DSA:2.60.40.10 180 270 1.2E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS41935 9b95a6a7fe2c500be312c8163ac2e9cd 565 Pfam PF02018 Carbohydrate binding domain 39 154 4.6E-14 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 SMD44_RS35760 c06dbc792d45ae6226bdbb6e3261050b 456 Gene3D G3DSA:1.10.530.10 245 400 1.1E-13 T 28-03-2018 SMD44_RS35760 c06dbc792d45ae6226bdbb6e3261050b 456 Gene3D G3DSA:1.10.287.700 147 244 2.2E-4 T 28-03-2018 SMD44_RS35760 c06dbc792d45ae6226bdbb6e3261050b 456 SUPERFAMILY SSF53955 267 375 1.95E-12 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS35760 c06dbc792d45ae6226bdbb6e3261050b 456 Pfam PF01464 Transglycosylase SLT domain 296 379 2.9E-7 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SMD44_RS42540 7e8e87e3eff941c39e9e3d61f5acc746 410 Gene3D G3DSA:3.30.470.20 120 394 3.1E-4 T 28-03-2018 SMD44_RS42540 7e8e87e3eff941c39e9e3d61f5acc746 410 Gene3D G3DSA:3.40.50.20 27 119 2.1E-5 T 28-03-2018 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 Gene3D G3DSA:3.50.50.60 39 169 2.6E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 28 220 8.8E-27 T 28-03-2018 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 SUPERFAMILY SSF51905 181 222 3.37E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 SUPERFAMILY SSF51905 279 394 3.37E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 Gene3D G3DSA:3.50.50.60 170 329 3.7E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 Gene3D G3DSA:3.90.180.10 2 38 0.077 T 28-03-2018 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 SUPERFAMILY SSF51905 26 228 4.53E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 187 205 6.2E-7 T 28-03-2018 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 26 45 6.2E-7 T 28-03-2018 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 183 207 8.9E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 25 47 8.9E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 152 8.9E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS17990 d53109b0bf45a917c284e62c350a0227 398 PIRSF PIRSF000332 22 345 3.8E-27 T 28-03-2018 SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 SUPERFAMILY SSF52440 90 135 1.15E-20 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 SUPERFAMILY SSF52440 1 48 1.15E-20 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 Pfam PF01820 D-ala D-ala ligase N-terminus 2 124 2.9E-17 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 Gene3D G3DSA:3.30.470.20 203 350 2.3E-29 T 28-03-2018 SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 Gene3D G3DSA:3.30.1490.20 117 202 4.2E-8 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 284 312 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 Gene3D G3DSA:3.40.50.20 1 116 2.8E-22 T 28-03-2018 SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 Pfam PF07478 D-ala D-ala ligase C-terminus 143 338 8.2E-25 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS04085 04db4183dc6c3bfed91e8e506119e929 350 SUPERFAMILY SSF56059 136 338 4.71E-33 T 28-03-2018 SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 243 300 1.5E-15 T 28-03-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 Gene3D G3DSA:3.30.2350.10 7 235 1.6E-79 T 28-03-2018 SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 187 1.1E-46 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 Gene3D G3DSA:2.30.130.10 236 300 3.4E-14 T 28-03-2018 IPR002478 PUA domain GO:0003723 SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 188 230 4.9E-13 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 8 300 16.8 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 SUPERFAMILY SSF55120 8 230 3.2E-69 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 SUPERFAMILY SSF88697 243 300 1.44E-8 T 28-03-2018 IPR015947 PUA-like domain SMD44_RS30880 65f9cbc4076cc0c16f9884db7ff9e5cf 301 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 9 226 1.5E-64 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS24770 2eb611307e629c22a6784d2a7bd5f50b 325 Gene3D G3DSA:3.40.50.20 1 132 5.6E-4 T 28-03-2018 SMD44_RS24770 2eb611307e629c22a6784d2a7bd5f50b 325 Gene3D G3DSA:3.30.470.20 133 325 1.0E-14 T 28-03-2018 SMD44_RS24770 2eb611307e629c22a6784d2a7bd5f50b 325 Pfam PF08443 RimK-like ATP-grasp domain 137 318 4.5E-6 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 SMD44_RS24770 2eb611307e629c22a6784d2a7bd5f50b 325 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 320 2.2E-115 T 28-03-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family SMD44_RS24770 2eb611307e629c22a6784d2a7bd5f50b 325 SUPERFAMILY SSF56059 136 321 1.14E-21 T 28-03-2018 SMD44_RS19295 78b7292a143952f0460ef05cbb8b9b5d 281 Gene3D G3DSA:3.40.50.1820 7 277 1.2E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS19295 78b7292a143952f0460ef05cbb8b9b5d 281 Pfam PF12697 Alpha/beta hydrolase family 54 260 3.0E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS19295 78b7292a143952f0460ef05cbb8b9b5d 281 SUPERFAMILY SSF53474 24 270 3.0E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 SMART SM00421 154 211 2.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 SMART SM00448 3 117 2.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 Pfam PF00072 Response regulator receiver domain 5 117 3.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 SUPERFAMILY SSF46894 147 217 7.14E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 SUPERFAMILY SSF52172 2 135 5.41E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 Gene3D G3DSA:3.40.50.2300 2 135 2.8E-37 T 28-03-2018 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 1.3E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 1.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 1.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 1.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS26875 13c494efd6d708bb442b595960201c91 230 Gene3D G3DSA:1.10.10.10 136 216 1.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10200 5c8cea77646e0427f5c7065516646137 232 SUPERFAMILY SSF55718 148 230 2.35E-16 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS10200 5c8cea77646e0427f5c7065516646137 232 Pfam PF07398 MDMPI C-terminal domain 147 224 8.0E-7 T 28-03-2018 IPR010872 MDMPI C-terminal SMD44_RS10200 5c8cea77646e0427f5c7065516646137 232 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 209 4.9E-36 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS10200 5c8cea77646e0427f5c7065516646137 232 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 140 2.7E-21 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS10200 5c8cea77646e0427f5c7065516646137 232 SUPERFAMILY SSF109854 2 146 1.26E-35 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS10200 5c8cea77646e0427f5c7065516646137 232 Gene3D G3DSA:1.20.120.450 3 144 1.5E-15 T 28-03-2018 SMD44_RS02840 7b1da874cd8d46d2c24647e0fb9cb81f 346 Gene3D G3DSA:3.40.50.300 16 341 2.0E-73 T 28-03-2018 SMD44_RS02840 7b1da874cd8d46d2c24647e0fb9cb81f 346 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS02840 7b1da874cd8d46d2c24647e0fb9cb81f 346 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 309 2.1E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS02840 7b1da874cd8d46d2c24647e0fb9cb81f 346 Pfam PF00005 ABC transporter 40 195 1.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS02840 7b1da874cd8d46d2c24647e0fb9cb81f 346 SMART SM00382 48 245 6.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS02840 7b1da874cd8d46d2c24647e0fb9cb81f 346 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 246 338 4.8E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS02840 7b1da874cd8d46d2c24647e0fb9cb81f 346 SUPERFAMILY SSF52540 19 266 1.94E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 Pfam PF14579 Helix-hairpin-helix motif 776 865 6.5E-21 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 21 1032 11.895 T 28-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 Gene3D G3DSA:3.20.20.140 21 229 2.5E-35 T 28-03-2018 SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 Pfam PF02811 PHP domain 23 147 5.1E-16 T 28-03-2018 IPR004013 PHP domain GO:0003824 SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 SMART SM00481 22 89 1.3E-15 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 Gene3D G3DSA:2.40.50.140 883 1025 7.2E-5 T 28-03-2018 SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 21 867 4.5E-170 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 SUPERFAMILY SSF89550 22 216 7.26E-14 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD44_RS08820 ed8b7857e011c8f3ff4cb4cba3d87877 1034 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 290 702 3.1E-134 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS05545 02b9999ad1f17c5c0c940a2b2f2d0b95 314 SUPERFAMILY SSF55347 144 247 7.19E-12 T 28-03-2018 SMD44_RS05545 02b9999ad1f17c5c0c940a2b2f2d0b95 314 Gene3D G3DSA:3.30.360.10 132 306 1.1E-20 T 28-03-2018 SMD44_RS05545 02b9999ad1f17c5c0c940a2b2f2d0b95 314 SUPERFAMILY SSF51735 3 134 3.79E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS05545 02b9999ad1f17c5c0c940a2b2f2d0b95 314 Gene3D G3DSA:3.40.50.720 1 131 2.6E-31 T 28-03-2018 SMD44_RS05545 02b9999ad1f17c5c0c940a2b2f2d0b95 314 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 118 7.1E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS01810 721c5cfc00b6c174ddd26f0a484ce21c 360 PIRSF PIRSF037238 1 360 5.2E-115 T 28-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase SMD44_RS01810 721c5cfc00b6c174ddd26f0a484ce21c 360 Pfam PF07687 Peptidase dimerisation domain 158 254 9.8E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS01810 721c5cfc00b6c174ddd26f0a484ce21c 360 Gene3D G3DSA:3.40.630.10 1 359 3.3E-42 T 28-03-2018 SMD44_RS01810 721c5cfc00b6c174ddd26f0a484ce21c 360 SUPERFAMILY SSF55031 161 257 1.23E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS01810 721c5cfc00b6c174ddd26f0a484ce21c 360 SUPERFAMILY SSF53187 1 170 4.29E-37 T 28-03-2018 SMD44_RS01810 721c5cfc00b6c174ddd26f0a484ce21c 360 SUPERFAMILY SSF53187 284 356 4.29E-37 T 28-03-2018 SMD44_RS01810 721c5cfc00b6c174ddd26f0a484ce21c 360 Pfam PF01546 Peptidase family M20/M25/M40 61 356 3.0E-21 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS06535 3a924c157b937e1958d751ee498b9045 183 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 36 61 0.0011 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS06535 3a924c157b937e1958d751ee498b9045 183 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 141 173 0.0029 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS06535 3a924c157b937e1958d751ee498b9045 183 Gene3D G3DSA:1.10.1780.10 23 181 8.9E-24 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS06535 3a924c157b937e1958d751ee498b9045 183 SUPERFAMILY SSF81923 114 177 4.84E-6 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS38170 67058ac4d5c5d1e95264c4b511624116 277 SUPERFAMILY SSF55781 140 273 3.27E-17 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS38170 67058ac4d5c5d1e95264c4b511624116 277 Pfam PF13466 STAS domain 34 110 1.5E-13 T 28-03-2018 IPR002645 STAS domain SMD44_RS38170 67058ac4d5c5d1e95264c4b511624116 277 Gene3D G3DSA:3.30.450.40 122 276 4.0E-18 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS38170 67058ac4d5c5d1e95264c4b511624116 277 Gene3D G3DSA:3.30.750.24 18 121 7.9E-16 T 28-03-2018 IPR002645 STAS domain SMD44_RS38170 67058ac4d5c5d1e95264c4b511624116 277 Pfam PF01590 GAF domain 188 273 2.2E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS38170 67058ac4d5c5d1e95264c4b511624116 277 SUPERFAMILY SSF52091 23 126 1.33E-14 T 28-03-2018 IPR002645 STAS domain SMD44_RS31865 cf059005d6957378c87be60ba3d90576 304 SUPERFAMILY SSF53474 56 287 1.02E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS31865 cf059005d6957378c87be60ba3d90576 304 Gene3D G3DSA:3.40.50.1820 52 299 1.4E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS31865 cf059005d6957378c87be60ba3d90576 304 Pfam PF00975 Thioesterase domain 72 290 3.2E-42 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS37040 79d0a6be7507c45f21f3c0f46fe68af1 341 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 328 9.1E-45 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS37040 79d0a6be7507c45f21f3c0f46fe68af1 341 Gene3D G3DSA:1.10.3470.10 55 334 2.6E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 TIGRFAM TIGR00232 tktlase_bact: transketolase 18 695 6.0E-242 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 SMART SM00861 371 555 3.2E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 ProSitePatterns PS00801 Transketolase signature 1. 24 44 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 355 4.4E-140 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 Gene3D G3DSA:3.40.50.920 566 696 1.4E-29 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 Pfam PF02779 Transketolase, pyrimidine binding domain 370 533 1.6E-42 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 Gene3D G3DSA:3.40.50.970 368 565 1.9E-45 T 28-03-2018 SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 SUPERFAMILY SSF52922 562 698 1.96E-38 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 Gene3D G3DSA:3.40.50.970 4 367 3.5E-93 T 28-03-2018 SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 Pfam PF02780 Transketolase, C-terminal domain 581 689 3.3E-10 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 SUPERFAMILY SSF52518 5 337 6.92E-106 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS10065 672ca9bd84631e2374a12d45710c4a87 702 SUPERFAMILY SSF52518 358 557 4.21E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 Pfam PF01926 50S ribosome-binding GTPase 161 284 1.2E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 Gene3D G3DSA:2.70.210.12 3 156 2.1E-49 T 28-03-2018 IPR006169 GTP1/OBG domain SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 Gene3D G3DSA:3.40.50.300 159 342 1.3E-29 T 28-03-2018 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 330 2.9E-125 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 SUPERFAMILY SSF52540 153 338 2.45E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 Hamap MF_01454 GTPase Obg [obg]. 3 331 43.735 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 SUPERFAMILY SSF102741 355 434 1.44E-19 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 Pfam PF09269 Domain of unknown function (DUF1967) 357 432 1.6E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 357 433 7.2E-28 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 Pfam PF01018 GTP1/OBG 5 158 3.6E-50 T 28-03-2018 IPR006169 GTP1/OBG domain SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 SUPERFAMILY SSF82051 4 157 1.44E-45 T 28-03-2018 IPR006169 GTP1/OBG domain SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 4.7E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 4.7E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 4.7E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS13995 2ad5b6b073a965154588383de9330fe1 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 4.7E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS06745 559798992329209fd10e737af9e92c36 1045 SUPERFAMILY SSF55874 503 624 8.77E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06745 559798992329209fd10e737af9e92c36 1045 Gene3D G3DSA:3.30.565.10 421 624 4.2E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06745 559798992329209fd10e737af9e92c36 1045 SMART SM00387 516 626 0.0095 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06745 559798992329209fd10e737af9e92c36 1045 Pfam PF08376 Nitrate and nitrite sensing 58 300 1.3E-29 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein SMD44_RS05640 cf91364de384831b40ee88ca4eda1efc 393 Gene3D G3DSA:1.10.443.10 174 373 8.5E-27 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS05640 cf91364de384831b40ee88ca4eda1efc 393 Pfam PF00589 Phage integrase family 186 370 4.3E-15 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS05640 cf91364de384831b40ee88ca4eda1efc 393 Gene3D G3DSA:1.10.150.130 70 154 1.7E-13 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS05640 cf91364de384831b40ee88ca4eda1efc 393 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 71 127 9.8E-6 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMD44_RS05640 cf91364de384831b40ee88ca4eda1efc 393 SUPERFAMILY SSF56349 71 370 1.71E-46 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Gene3D G3DSA:3.50.50.60 2 76 7.6E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Gene3D G3DSA:4.10.1250.10 682 721 1.5E-15 T 28-03-2018 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Gene3D G3DSA:3.30.9.10 165 335 1.6E-38 T 28-03-2018 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 SUPERFAMILY SSF54373 217 335 1.49E-29 T 28-03-2018 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Gene3D G3DSA:2.40.30.110 724 814 4.7E-18 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Pfam PF01266 FAD dependent oxidoreductase 3 372 8.7E-53 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 SUPERFAMILY SSF51905 336 419 3.89E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 SUPERFAMILY SSF51905 2 217 3.89E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 SUPERFAMILY SSF103025 425 719 6.59E-95 T 28-03-2018 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Pfam PF16350 FAD dependent oxidoreductase central domain 375 430 1.7E-19 T 28-03-2018 IPR032503 FAD dependent oxidoreductase, central domain SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Gene3D G3DSA:3.30.1360.120 427 573 2.6E-26 T 28-03-2018 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Gene3D G3DSA:3.30.1360.120 574 680 2.2E-19 T 28-03-2018 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 710 801 1.5E-11 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Pfam PF01571 Aminomethyltransferase folate-binding domain 432 704 6.7E-75 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 SUPERFAMILY SSF101790 726 813 1.1E-16 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain SMD44_RS06775 6f0fd81d4b2571bbad85e129ac9bf4fc 814 Gene3D G3DSA:3.30.9.10 84 164 9.0E-10 T 28-03-2018 SMD44_RS11210 48d6ca82db53a3d403fb60cf8c332a56 203 SUPERFAMILY SSF46689 19 85 3.08E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS11210 48d6ca82db53a3d403fb60cf8c332a56 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 6.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11210 48d6ca82db53a3d403fb60cf8c332a56 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 6.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11210 48d6ca82db53a3d403fb60cf8c332a56 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 1.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11210 48d6ca82db53a3d403fb60cf8c332a56 203 Gene3D G3DSA:1.10.357.10 3 203 4.9E-27 T 28-03-2018 SMD44_RS03870 5700e98f6deb817e4ec890c3dc30ba5b 378 SUPERFAMILY SSF51735 4 151 8.78E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS03870 5700e98f6deb817e4ec890c3dc30ba5b 378 SUPERFAMILY SSF55347 133 294 2.78E-26 T 28-03-2018 SMD44_RS03870 5700e98f6deb817e4ec890c3dc30ba5b 378 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 120 8.7E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS03870 5700e98f6deb817e4ec890c3dc30ba5b 378 Gene3D G3DSA:3.30.360.10 144 358 5.5E-36 T 28-03-2018 SMD44_RS03870 5700e98f6deb817e4ec890c3dc30ba5b 378 Gene3D G3DSA:3.40.50.720 1 143 4.0E-30 T 28-03-2018 SMD44_RS21605 64819844412907248e367d067f48405e 1001 Gene3D G3DSA:1.25.40.10 424 746 1.0E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS21605 64819844412907248e367d067f48405e 1001 SUPERFAMILY SSF46894 927 996 1.33E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS21605 64819844412907248e367d067f48405e 1001 Gene3D G3DSA:1.25.40.10 749 927 1.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS21605 64819844412907248e367d067f48405e 1001 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 971 983 3.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21605 64819844412907248e367d067f48405e 1001 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 941 955 3.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21605 64819844412907248e367d067f48405e 1001 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 955 971 3.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21605 64819844412907248e367d067f48405e 1001 Gene3D G3DSA:1.10.10.10 930 999 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21605 64819844412907248e367d067f48405e 1001 SMART SM00382 82 239 5.1E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS21605 64819844412907248e367d067f48405e 1001 Pfam PF13191 AAA ATPase domain 61 206 3.7E-17 T 28-03-2018 SMD44_RS21605 64819844412907248e367d067f48405e 1001 SMART SM00421 938 995 2.1E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21605 64819844412907248e367d067f48405e 1001 Gene3D G3DSA:3.40.50.300 61 231 2.1E-11 T 28-03-2018 SMD44_RS21605 64819844412907248e367d067f48405e 1001 SUPERFAMILY SSF52540 59 139 1.19E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21605 64819844412907248e367d067f48405e 1001 SUPERFAMILY SSF52540 167 280 1.19E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21605 64819844412907248e367d067f48405e 1001 SUPERFAMILY SSF48452 688 719 9.25E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS21605 64819844412907248e367d067f48405e 1001 SUPERFAMILY SSF48452 877 906 9.25E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS21605 64819844412907248e367d067f48405e 1001 SUPERFAMILY SSF48452 762 834 9.25E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS21605 64819844412907248e367d067f48405e 1001 Pfam PF00196 Bacterial regulatory proteins, luxR family 941 993 5.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21605 64819844412907248e367d067f48405e 1001 ProSitePatterns PS00622 LuxR-type HTH domain signature. 955 982 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS21605 64819844412907248e367d067f48405e 1001 Gene3D G3DSA:1.10.10.10 288 382 6.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22410 5ade435f58ad536c8c8513b8f4371d55 165 SUPERFAMILY SSF53271 9 151 6.42E-25 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS22410 5ade435f58ad536c8c8513b8f4371d55 165 Gene3D G3DSA:3.40.50.2020 3 159 1.4E-25 T 28-03-2018 SMD44_RS22410 5ade435f58ad536c8c8513b8f4371d55 165 Pfam PF00156 Phosphoribosyl transferase domain 13 152 2.8E-23 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD44_RS33045 245035530eef0da5e0b26f4239d28f3f 406 Pfam PF13478 XdhC Rossmann domain 229 371 3.0E-41 T 28-03-2018 IPR027051 XdhC Rossmann domain SMD44_RS33045 245035530eef0da5e0b26f4239d28f3f 406 Pfam PF02625 XdhC and CoxI family 11 78 1.6E-23 T 28-03-2018 IPR003777 XdhC- CoxI SMD44_RS04000 1373ebed12d32f25184e464b939eb09e 368 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 38 324 3.2E-45 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS04000 1373ebed12d32f25184e464b939eb09e 368 Gene3D G3DSA:3.40.50.1100 152 339 3.5E-37 T 28-03-2018 SMD44_RS04000 1373ebed12d32f25184e464b939eb09e 368 Gene3D G3DSA:3.40.50.1100 40 151 6.8E-23 T 28-03-2018 SMD44_RS04000 1373ebed12d32f25184e464b939eb09e 368 SUPERFAMILY SSF53686 33 345 1.57E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS02240 69dcd3121c628ec69a8383d3ebeb003f 356 Gene3D G3DSA:3.20.20.70 1 356 8.9E-118 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS02240 69dcd3121c628ec69a8383d3ebeb003f 356 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 332 1.4E-74 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD44_RS02240 69dcd3121c628ec69a8383d3ebeb003f 356 SUPERFAMILY SSF51395 2 354 4.12E-110 T 28-03-2018 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 298 2.8E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 SUPERFAMILY SSF55874 290 449 3.01E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 SUPERFAMILY SSF47384 220 300 1.22E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 SMART SM00304 184 236 4.4E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 SMART SM00388 237 300 1.8E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 SUPERFAMILY SSF158472 185 233 4.84E-9 T 28-03-2018 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 2.8E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 2.8E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 2.8E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 2.8E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 Gene3D G3DSA:3.30.565.10 303 452 1.9E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 Gene3D G3DSA:1.10.287.130 227 296 5.6E-18 T 28-03-2018 SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 SMART SM00387 341 453 1.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 451 6.5E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11340 fc04582571bd1ddd6a9b985cbbe9ae85 453 Pfam PF00672 HAMP domain 185 233 6.6E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 Pfam PF16499 Alpha galactosidase A 56 327 3.3E-83 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 Gene3D G3DSA:2.60.40.10 426 534 7.5E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 SMART SM00776 536 681 5.5E-74 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 SUPERFAMILY SSF49785 539 680 2.04E-42 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 PRINTS PR00740 Glycosyl hydrolase family 27 signature 130 151 1.9E-57 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 PRINTS PR00740 Glycosyl hydrolase family 27 signature 89 104 1.9E-57 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 PRINTS PR00740 Glycosyl hydrolase family 27 signature 166 183 1.9E-57 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 PRINTS PR00740 Glycosyl hydrolase family 27 signature 51 70 1.9E-57 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 PRINTS PR00740 Glycosyl hydrolase family 27 signature 262 281 1.9E-57 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 PRINTS PR00740 Glycosyl hydrolase family 27 signature 283 304 1.9E-57 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 PRINTS PR00740 Glycosyl hydrolase family 27 signature 197 215 1.9E-57 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 Gene3D G3DSA:3.20.20.70 197 324 8.0E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 Gene3D G3DSA:3.20.20.70 38 196 3.5E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 Pfam PF08305 NPCBM/NEW2 domain 539 679 1.9E-48 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 SUPERFAMILY SSF51011 329 414 2.28E-20 T 28-03-2018 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 SUPERFAMILY SSF51445 48 328 3.19E-99 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 ProSitePatterns PS00512 Alpha-galactosidase signature. 94 110 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 Gene3D G3DSA:2.60.40.1180 325 420 1.6E-20 T 28-03-2018 SMD44_RS04785 44d5ac3f3668a4576519b08a01f87826 681 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 437 513 2.9E-18 T 28-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 Gene3D G3DSA:3.50.50.60 2 182 2.3E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 1.4E-23 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 220 1.4E-23 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 331 353 1.4E-23 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 322 1.4E-23 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.4E-23 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 Pfam PF14759 Reductase C-terminal 391 459 7.7E-13 T 28-03-2018 IPR028202 Reductase, C-terminal SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 SUPERFAMILY SSF51905 200 380 1.2E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 368 1.0E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 Gene3D G3DSA:3.50.50.60 183 236 2.9E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 Gene3D G3DSA:3.30.390.30 386 462 1.3E-21 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 SUPERFAMILY SSF55424 387 459 6.59E-19 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 Gene3D G3DSA:3.50.50.60 237 380 4.5E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 346 353 4.5E-20 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 202 227 4.5E-20 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 321 4.5E-20 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.5E-20 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 170 4.5E-20 T 28-03-2018 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 SUPERFAMILY SSF51905 4 69 8.83E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06755 928e4a35c46f38a8adb5666633f58064 462 SUPERFAMILY SSF51905 113 244 8.83E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS29585 a1a22a09a3c64dce01af573d9c2c2397 391 Gene3D G3DSA:2.130.10.10 179 254 2.0E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS29585 a1a22a09a3c64dce01af573d9c2c2397 391 Gene3D G3DSA:2.130.10.10 60 178 7.3E-19 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS29585 a1a22a09a3c64dce01af573d9c2c2397 391 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 82 117 2.8E-11 T 28-03-2018 IPR011964 YVTN beta-propeller repeat SMD44_RS29585 a1a22a09a3c64dce01af573d9c2c2397 391 Gene3D G3DSA:2.130.10.10 255 390 1.8E-28 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS29585 a1a22a09a3c64dce01af573d9c2c2397 391 SUPERFAMILY SSF51004 78 372 6.28E-64 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain SMD44_RS03935 104a9d4301658e4998cef0998ad18dfa 530 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 84 473 6.4E-80 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMD44_RS03935 104a9d4301658e4998cef0998ad18dfa 530 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 30 510 16.19 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMD44_RS03935 104a9d4301658e4998cef0998ad18dfa 530 SUPERFAMILY SSF56317 236 505 3.01E-44 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS03935 104a9d4301658e4998cef0998ad18dfa 530 Gene3D G3DSA:3.60.110.10 223 504 6.7E-43 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS03935 104a9d4301658e4998cef0998ad18dfa 530 Pfam PF00795 Carbon-nitrogen hydrolase 241 491 6.3E-21 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS31555 7b70a050fb8ee0401ab922ac0beecbee 399 Gene3D G3DSA:3.30.565.10 278 399 5.5E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31555 7b70a050fb8ee0401ab922ac0beecbee 399 SUPERFAMILY SSF55874 302 398 1.15E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31555 7b70a050fb8ee0401ab922ac0beecbee 399 Pfam PF07730 Histidine kinase 211 276 3.1E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS24720 966ca733d5eed72cf4637c30ffdaf082 399 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 360 5.9E-104 T 28-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD44_RS24720 966ca733d5eed72cf4637c30ffdaf082 399 SUPERFAMILY SSF102114 18 341 5.76E-50 T 28-03-2018 SMD44_RS24720 966ca733d5eed72cf4637c30ffdaf082 399 PIRSF PIRSF004762 1 373 2.1E-107 T 28-03-2018 SMD44_RS24720 966ca733d5eed72cf4637c30ffdaf082 399 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 360 6.8E-139 T 28-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD44_RS24720 966ca733d5eed72cf4637c30ffdaf082 399 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 363 50.401 T 28-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD44_RS24720 966ca733d5eed72cf4637c30ffdaf082 399 Gene3D G3DSA:3.20.20.70 1 362 5.2E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS24720 966ca733d5eed72cf4637c30ffdaf082 399 Pfam PF04055 Radical SAM superfamily 65 238 1.8E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS09435 2f3b28bd5b0a81f8c111f5ff6a693fc7 457 Gene3D G3DSA:3.40.50.10540 204 442 6.1E-67 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS09435 2f3b28bd5b0a81f8c111f5ff6a693fc7 457 Gene3D G3DSA:3.30.1540.10 89 183 9.8E-17 T 28-03-2018 SMD44_RS09435 2f3b28bd5b0a81f8c111f5ff6a693fc7 457 SUPERFAMILY SSF89796 26 200 2.62E-23 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS09435 2f3b28bd5b0a81f8c111f5ff6a693fc7 457 SUPERFAMILY SSF89796 209 411 1.12E-54 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS09435 2f3b28bd5b0a81f8c111f5ff6a693fc7 457 Pfam PF02515 CoA-transferase family III 211 412 3.6E-47 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMD44_RS30385 9e23339ba2e4e67eca8718170091ce44 93 Pfam PF00708 Acylphosphatase 8 92 5.6E-22 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD44_RS30385 9e23339ba2e4e67eca8718170091ce44 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD44_RS30385 9e23339ba2e4e67eca8718170091ce44 93 Gene3D G3DSA:3.30.70.100 1 93 8.6E-27 T 28-03-2018 SMD44_RS30385 9e23339ba2e4e67eca8718170091ce44 93 SUPERFAMILY SSF54975 3 93 5.01E-24 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD44_RS22100 92ea614886c33cbec8901951e53065a6 319 Gene3D G3DSA:3.30.470.20 116 297 3.7E-12 T 28-03-2018 SMD44_RS22100 92ea614886c33cbec8901951e53065a6 319 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 5 312 5.8E-118 T 28-03-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family SMD44_RS22100 92ea614886c33cbec8901951e53065a6 319 SUPERFAMILY SSF56059 117 313 2.05E-17 T 28-03-2018 SMD44_RS13830 5ba76303bb30c21e789b102187ef9c35 194 Gene3D G3DSA:3.40.50.2300 5 193 1.1E-38 T 28-03-2018 SMD44_RS13830 5ba76303bb30c21e789b102187ef9c35 194 Pfam PF00072 Response regulator receiver domain 13 125 6.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS13830 5ba76303bb30c21e789b102187ef9c35 194 SMART SM00448 11 125 8.7E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS13830 5ba76303bb30c21e789b102187ef9c35 194 SUPERFAMILY SSF52172 10 169 3.27E-37 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 SUPERFAMILY SSF47413 2 60 2.59E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 Gene3D G3DSA:3.40.50.2300 191 325 2.3E-47 T 28-03-2018 SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 SMART SM00354 2 72 6.3E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 SUPERFAMILY SSF53822 62 347 5.89E-63 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 Pfam PF13377 Periplasmic binding protein-like domain 185 344 3.0E-34 T 28-03-2018 SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 5.7E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 Gene3D G3DSA:3.40.50.2300 59 190 3.8E-32 T 28-03-2018 SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 SMD44_RS14815 ec62c326ee8d5f9e59e91bfd8faa3ea6 350 Gene3D G3DSA:1.10.260.40 3 58 1.2E-19 T 28-03-2018 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 Pfam PF02811 PHP domain 8 194 5.1E-45 T 28-03-2018 IPR004013 PHP domain GO:0003824 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 SMART SM00481 7 74 2.1E-28 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMD44_RS10910 423442bea952320c901bd3524a449156 1179 SUPERFAMILY SSF89550 7 268 7.75E-30 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 Pfam PF01336 OB-fold nucleic acid binding domain 1020 1096 1.0E-6 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 Pfam PF14579 Helix-hairpin-helix motif 829 917 3.1E-23 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 Gene3D G3DSA:2.40.50.140 1004 1096 3.2E-12 T 28-03-2018 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 Gene3D G3DSA:1.10.150.280 807 915 8.4E-8 T 28-03-2018 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 Gene3D G3DSA:3.20.20.140 5 275 3.9E-45 T 28-03-2018 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1057 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10910 423442bea952320c901bd3524a449156 1179 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 316 755 2.5E-164 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS35535 caafb272a42be3d3c1adf80e73e62a6d 340 Pfam PF13394 4Fe-4S single cluster domain 37 112 4.3E-5 T 28-03-2018 SMD44_RS35535 caafb272a42be3d3c1adf80e73e62a6d 340 Pfam PF11946 Domain of unknown function (DUF3463) 196 328 7.2E-56 T 28-03-2018 IPR022563 Domain of unknown function DUF3463 SMD44_RS35535 caafb272a42be3d3c1adf80e73e62a6d 340 Pfam PF04055 Radical SAM superfamily 34 187 4.9E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS35535 caafb272a42be3d3c1adf80e73e62a6d 340 SUPERFAMILY SSF102114 24 308 7.46E-48 T 28-03-2018 SMD44_RS35535 caafb272a42be3d3c1adf80e73e62a6d 340 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 318 7.0E-161 T 28-03-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH SMD44_RS35535 caafb272a42be3d3c1adf80e73e62a6d 340 Gene3D G3DSA:3.20.20.70 15 338 2.5E-29 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS19920 188ed25c7a92e6d4ba082823037fd3ee 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 1.2E-8 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD44_RS19920 188ed25c7a92e6d4ba082823037fd3ee 68 Gene3D G3DSA:1.10.1660.10 1 67 7.8E-13 T 28-03-2018 SMD44_RS19920 188ed25c7a92e6d4ba082823037fd3ee 68 Pfam PF12728 Helix-turn-helix domain 11 59 9.5E-12 T 28-03-2018 SMD44_RS19920 188ed25c7a92e6d4ba082823037fd3ee 68 SUPERFAMILY SSF46955 11 59 2.61E-11 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS02040 9e7f203b02fb98fb2b26bb0033dc083c 307 Gene3D G3DSA:3.40.710.10 4 307 4.1E-121 T 28-03-2018 SMD44_RS02040 9e7f203b02fb98fb2b26bb0033dc083c 307 Hamap MF_00313 Glutaminase [glsA]. 7 307 44.286 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD44_RS02040 9e7f203b02fb98fb2b26bb0033dc083c 307 TIGRFAM TIGR03814 Gln_ase: glutaminase A 11 307 1.2E-116 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD44_RS02040 9e7f203b02fb98fb2b26bb0033dc083c 307 SUPERFAMILY SSF56601 6 307 2.82E-102 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS02040 9e7f203b02fb98fb2b26bb0033dc083c 307 Pfam PF04960 Glutaminase 25 307 6.5E-105 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD44_RS13860 9da4640aa42c3e1397c46aa69336133a 293 Pfam PF13620 Carboxypeptidase regulatory-like domain 32 110 4.6E-10 T 28-03-2018 SMD44_RS13860 9da4640aa42c3e1397c46aa69336133a 293 SUPERFAMILY SSF49464 34 114 2.28E-8 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMD44_RS13860 9da4640aa42c3e1397c46aa69336133a 293 SMART SM00867 122 290 2.0E-53 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS13860 9da4640aa42c3e1397c46aa69336133a 293 Pfam PF04264 YceI-like domain 123 288 2.8E-36 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS13860 9da4640aa42c3e1397c46aa69336133a 293 Gene3D G3DSA:2.60.40.1120 30 115 1.5E-8 T 28-03-2018 SMD44_RS13860 9da4640aa42c3e1397c46aa69336133a 293 SUPERFAMILY SSF101874 121 291 6.8E-46 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS13860 9da4640aa42c3e1397c46aa69336133a 293 Gene3D G3DSA:2.40.128.110 118 293 5.1E-47 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 9.9E-35 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 SUPERFAMILY SSF53223 1 121 1.73E-36 T 28-03-2018 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 Gene3D G3DSA:3.40.50.10860 11 139 1.3E-42 T 28-03-2018 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 7.2E-61 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 7.2E-61 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 7.2E-61 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 7.2E-61 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 7.2E-61 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 7.2E-61 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 282 4.7E-61 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 SUPERFAMILY SSF51735 122 281 2.76E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 Gene3D G3DSA:3.40.50.720 140 264 1.9E-29 T 28-03-2018 SMD44_RS26060 a73d33ff1b66ca637c83327c9847a625 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 36.178 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD44_RS18205 639751c14dd4a90b6406d2ec19844c7c 258 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS18205 639751c14dd4a90b6406d2ec19844c7c 258 SUPERFAMILY SSF52540 26 247 1.5E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18205 639751c14dd4a90b6406d2ec19844c7c 258 SMART SM00382 51 238 2.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS18205 639751c14dd4a90b6406d2ec19844c7c 258 Pfam PF00005 ABC transporter 42 190 8.0E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS18205 639751c14dd4a90b6406d2ec19844c7c 258 Gene3D G3DSA:3.40.50.300 22 254 1.5E-67 T 28-03-2018 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 Gene3D G3DSA:3.90.1150.10 4 161 2.9E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 PIRSF PIRSF000521 2 161 2.6E-8 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 PIRSF PIRSF000521 175 400 1.3E-28 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 Pfam PF00202 Aminotransferase class-III 16 399 3.6E-115 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 Gene3D G3DSA:3.90.1150.10 295 400 1.8E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 5 398 2.0E-148 T 28-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 Gene3D G3DSA:3.40.640.10 171 294 1.2E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS26400 c8c80de7140da58fa9a7c4b9dbbb5fa0 400 SUPERFAMILY SSF53383 4 399 3.67E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS27690 4e0eb69ad196240638c8c6ff8cb7de7a 309 SUPERFAMILY SSF161098 91 290 3.66E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS27690 4e0eb69ad196240638c8c6ff8cb7de7a 309 Gene3D G3DSA:1.10.3720.10 2 300 3.8E-44 T 28-03-2018 SMD44_RS27690 4e0eb69ad196240638c8c6ff8cb7de7a 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 308 1.9E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15650 0a03c947d6da3ece2b69bd82a6a36408 316 Gene3D G3DSA:3.40.50.1100 22 134 7.8E-38 T 28-03-2018 SMD44_RS15650 0a03c947d6da3ece2b69bd82a6a36408 316 Gene3D G3DSA:3.40.50.1100 135 309 5.0E-41 T 28-03-2018 SMD44_RS15650 0a03c947d6da3ece2b69bd82a6a36408 316 SUPERFAMILY SSF53686 5 295 1.83E-88 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS15650 0a03c947d6da3ece2b69bd82a6a36408 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SMD44_RS15650 0a03c947d6da3ece2b69bd82a6a36408 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 298 4.9E-111 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 SMD44_RS15650 0a03c947d6da3ece2b69bd82a6a36408 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 1.6E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS16775 e15040fa65fd761f59158ca0bc07d62a 314 Gene3D G3DSA:3.30.420.40 1 118 2.3E-50 T 28-03-2018 SMD44_RS16775 e15040fa65fd761f59158ca0bc07d62a 314 Gene3D G3DSA:3.30.420.150 119 313 1.2E-56 T 28-03-2018 SMD44_RS16775 e15040fa65fd761f59158ca0bc07d62a 314 SUPERFAMILY SSF53067 134 313 6.2E-39 T 28-03-2018 SMD44_RS16775 e15040fa65fd761f59158ca0bc07d62a 314 Pfam PF02541 Ppx/GppA phosphatase family 26 305 3.3E-56 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SMD44_RS16775 e15040fa65fd761f59158ca0bc07d62a 314 SUPERFAMILY SSF53067 3 124 6.29E-34 T 28-03-2018 SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 Gene3D G3DSA:1.25.60.10 160 272 5.7E-27 T 28-03-2018 SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 SUPERFAMILY SSF54631 280 412 6.06E-23 T 28-03-2018 SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 Gene3D G3DSA:3.10.580.10 273 422 5.6E-18 T 28-03-2018 SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 SUPERFAMILY SSF50346 11 74 6.75E-7 T 28-03-2018 IPR011033 PRC-barrel-like SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 Gene3D G3DSA:2.30.30.240 8 77 1.3E-10 T 28-03-2018 SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 Pfam PF00571 CBS domain 350 404 6.8E-4 T 28-03-2018 IPR000644 CBS domain SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 Pfam PF00571 CBS domain 282 342 0.0028 T 28-03-2018 IPR000644 CBS domain SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 Pfam PF03448 MgtE intracellular N domain 178 278 1.5E-27 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 SUPERFAMILY SSF158791 166 278 2.88E-32 T 28-03-2018 SMD44_RS27895 e385ee181602cbc2e8a2e728387d3574 425 SMART SM00924 178 281 4.2E-36 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain SMD44_RS09725 81001a6ab5d9548ca77ab460bcc37688 382 Pfam PF00266 Aminotransferase class-V 39 375 1.8E-15 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS09725 81001a6ab5d9548ca77ab460bcc37688 382 Gene3D G3DSA:3.90.1150.10 302 381 1.0E-12 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS09725 81001a6ab5d9548ca77ab460bcc37688 382 Gene3D G3DSA:3.40.640.10 49 301 1.5E-25 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS09725 81001a6ab5d9548ca77ab460bcc37688 382 SUPERFAMILY SSF53383 34 380 1.03E-48 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 Pfam PF01037 Lrp/AsnC ligand binding domain 89 158 5.1E-16 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 SUPERFAMILY SSF54909 85 166 1.34E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 Gene3D G3DSA:3.30.70.920 76 166 3.3E-18 T 28-03-2018 SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 ProSitePatterns PS00519 AsnC-type HTH domain signature. 42 68 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 Gene3D G3DSA:1.10.10.10 22 75 1.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 Pfam PF13404 AsnC-type helix-turn-helix domain 24 64 5.6E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 SMART SM00344 24 128 4.1E-36 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 SUPERFAMILY SSF46785 24 78 9.09E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 51 3.6E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 40 3.6E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS30640 38e204c1638ba8b3e92ded4af2d771e4 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 51 70 3.6E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS00610 aca0decd8a6ac15f50084a483156a632 392 Gene3D G3DSA:3.40.50.1460 7 291 1.4E-22 T 28-03-2018 SMD44_RS00610 aca0decd8a6ac15f50084a483156a632 392 SUPERFAMILY SSF52129 99 281 1.05E-9 T 28-03-2018 IPR029030 Caspase-like domain SMD44_RS00610 aca0decd8a6ac15f50084a483156a632 392 Pfam PF00656 Caspase domain 82 253 1.2E-5 T 28-03-2018 SMD44_RS19000 d481bce07fda985f7943358328a96d3a 157 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4 154 2.5E-41 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD44_RS19000 d481bce07fda985f7943358328a96d3a 157 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 37 52 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD44_RS19000 d481bce07fda985f7943358328a96d3a 157 SUPERFAMILY SSF69765 3 155 9.29E-48 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD44_RS19000 d481bce07fda985f7943358328a96d3a 157 Gene3D G3DSA:3.30.1330.50 1 157 1.4E-55 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD44_RS19000 d481bce07fda985f7943358328a96d3a 157 Pfam PF02542 YgbB family 4 153 4.8E-44 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD44_RS19000 d481bce07fda985f7943358328a96d3a 157 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 155 30.085 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 Pfam PF00550 Phosphopantetheine attachment site 288 353 7.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 SUPERFAMILY SSF47336 280 363 1.01E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 SMART SM01294 286 353 3.7E-5 T 28-03-2018 SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 ProSitePatterns PS00012 Phosphopantetheine attachment site. 312 327 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 Gene3D G3DSA:1.10.1200.10 255 360 1.3E-21 T 28-03-2018 SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 1.9E-57 T 28-03-2018 SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 SMART SM00823 Phosphopantetheine attachment site 285 357 1.3E-30 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 SUPERFAMILY SSF51735 3 234 5.67E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 Gene3D G3DSA:3.40.50.720 3 254 9.3E-51 T 28-03-2018 SMD44_RS36535 312b3e194897b805f3f10ad16a955a59 446 Pfam PF08659 KR domain 9 188 5.9E-60 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS14480 76fde8230b09f063501e1ef99516dd94 338 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 20 315 3.9E-14 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 SMD44_RS14480 76fde8230b09f063501e1ef99516dd94 338 SUPERFAMILY SSF53067 17 122 9.5E-14 T 28-03-2018 SMD44_RS14480 76fde8230b09f063501e1ef99516dd94 338 Gene3D G3DSA:3.30.420.40 11 139 1.1E-15 T 28-03-2018 SMD44_RS14480 76fde8230b09f063501e1ef99516dd94 338 SUPERFAMILY SSF53067 131 321 1.11E-30 T 28-03-2018 SMD44_RS14480 76fde8230b09f063501e1ef99516dd94 338 Gene3D G3DSA:3.30.420.40 140 294 1.2E-32 T 28-03-2018 SMD44_RS36215 73eaa955c98880534193c33a18593ef2 93 Gene3D G3DSA:1.10.1200.10 1 92 1.6E-14 T 28-03-2018 SMD44_RS36215 73eaa955c98880534193c33a18593ef2 93 Pfam PF00550 Phosphopantetheine attachment site 6 72 4.9E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36215 73eaa955c98880534193c33a18593ef2 93 SUPERFAMILY SSF47336 2 88 1.3E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS34925 435448667e30817c82de833b41733b61 351 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 94 6.1E-11 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS34925 435448667e30817c82de833b41733b61 351 Gene3D G3DSA:3.40.50.720 1 127 1.7E-19 T 28-03-2018 SMD44_RS34925 435448667e30817c82de833b41733b61 351 SUPERFAMILY SSF51735 1 128 3.18E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34925 435448667e30817c82de833b41733b61 351 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 153 225 2.7E-8 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS34925 435448667e30817c82de833b41733b61 351 Gene3D G3DSA:3.30.360.10 128 317 2.1E-33 T 28-03-2018 SMD44_RS34925 435448667e30817c82de833b41733b61 351 SUPERFAMILY SSF55347 139 292 4.91E-22 T 28-03-2018 SMD44_RS21965 3c526304c3bd02721713892ea086f8b8 194 SUPERFAMILY SSF48498 82 188 7.91E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS21965 3c526304c3bd02721713892ea086f8b8 194 Gene3D G3DSA:1.10.357.10 81 194 1.4E-13 T 28-03-2018 SMD44_RS21965 3c526304c3bd02721713892ea086f8b8 194 Gene3D G3DSA:1.10.260.40 36 80 2.7E-7 T 28-03-2018 SMD44_RS21965 3c526304c3bd02721713892ea086f8b8 194 Gene3D G3DSA:1.10.10.60 1 35 1.9E-10 T 28-03-2018 SMD44_RS21965 3c526304c3bd02721713892ea086f8b8 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21965 3c526304c3bd02721713892ea086f8b8 194 SUPERFAMILY SSF46689 9 77 5.99E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 SUPERFAMILY SSF55781 26 188 5.02E-16 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 SMART SM01012 188 243 7.9E-10 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 SUPERFAMILY SSF52172 168 243 5.47E-6 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 Pfam PF03861 ANTAR domain 191 243 1.2E-11 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 Gene3D G3DSA:1.10.10.10 201 244 3.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 Pfam PF13185 GAF domain 30 173 1.2E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 SMART SM00065 25 186 0.0087 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 PIRSF PIRSF036625 1 251 3.9E-37 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS15345 5b202163aed4c804ff8c6f199a7e5476 257 Gene3D G3DSA:3.30.450.40 1 200 3.1E-23 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS19345 96e0eca59e88588e2f6199727dff606b 147 Gene3D G3DSA:1.10.10.10 1 79 2.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19345 96e0eca59e88588e2f6199727dff606b 147 SUPERFAMILY SSF46785 7 80 1.32E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19345 96e0eca59e88588e2f6199727dff606b 147 SMART SM00345 18 77 5.4E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19345 96e0eca59e88588e2f6199727dff606b 147 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 6.9E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS31620 81341f1a7d9182334d8064d9d9649d26 448 Gene3D G3DSA:3.30.830.10 16 239 6.1E-66 T 28-03-2018 SMD44_RS31620 81341f1a7d9182334d8064d9d9649d26 448 Gene3D G3DSA:3.30.830.10 244 446 1.1E-28 T 28-03-2018 SMD44_RS31620 81341f1a7d9182334d8064d9d9649d26 448 SUPERFAMILY SSF63411 19 231 7.15E-60 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD44_RS31620 81341f1a7d9182334d8064d9d9649d26 448 Pfam PF00675 Insulinase (Peptidase family M16) 28 147 1.5E-21 T 28-03-2018 IPR011765 Peptidase M16, N-terminal SMD44_RS31620 81341f1a7d9182334d8064d9d9649d26 448 Pfam PF05193 Peptidase M16 inactive domain 187 366 4.6E-31 T 28-03-2018 IPR007863 Peptidase M16, C-terminal SMD44_RS31620 81341f1a7d9182334d8064d9d9649d26 448 SUPERFAMILY SSF63411 248 440 2.33E-26 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 SUPERFAMILY SSF53067 265 508 1.94E-81 T 28-03-2018 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 Hamap MF_00186 Glycerol kinase [glpK]. 8 508 55.819 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 9 507 9.1E-227 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 11 262 8.6E-82 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 271 461 9.2E-63 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 Gene3D G3DSA:3.30.420.40 259 513 2.4E-79 T 28-03-2018 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 Gene3D G3DSA:3.30.420.40 6 258 5.3E-93 T 28-03-2018 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 SUPERFAMILY SSF53067 10 265 9.5E-92 T 28-03-2018 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 373 393 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD44_RS08240 fa24fb62be3027e1717dadeaf654b5e1 513 PIRSF PIRSF000538 8 513 1.2E-165 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD44_RS23035 4d2294bcce7041feedccd5617d1762b7 405 SUPERFAMILY SSF63411 229 392 6.0E-29 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD44_RS23035 4d2294bcce7041feedccd5617d1762b7 405 Pfam PF05193 Peptidase M16 inactive domain 217 339 1.1E-17 T 28-03-2018 IPR007863 Peptidase M16, C-terminal SMD44_RS23035 4d2294bcce7041feedccd5617d1762b7 405 Pfam PF00675 Insulinase (Peptidase family M16) 21 158 1.7E-16 T 28-03-2018 IPR011765 Peptidase M16, N-terminal SMD44_RS23035 4d2294bcce7041feedccd5617d1762b7 405 Gene3D G3DSA:3.30.830.10 238 396 9.1E-28 T 28-03-2018 SMD44_RS23035 4d2294bcce7041feedccd5617d1762b7 405 Gene3D G3DSA:3.30.830.10 11 227 5.4E-32 T 28-03-2018 SMD44_RS23035 4d2294bcce7041feedccd5617d1762b7 405 SUPERFAMILY SSF63411 11 191 1.33E-31 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD44_RS09010 bced975d3bb42b2f60dcbc8fb1423d01 229 SMART SM00382 29 207 3.8E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS09010 bced975d3bb42b2f60dcbc8fb1423d01 229 SUPERFAMILY SSF52540 4 222 1.66E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09010 bced975d3bb42b2f60dcbc8fb1423d01 229 Pfam PF00005 ABC transporter 21 161 4.2E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS09010 bced975d3bb42b2f60dcbc8fb1423d01 229 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS09010 bced975d3bb42b2f60dcbc8fb1423d01 229 Gene3D G3DSA:3.40.50.300 1 228 6.3E-37 T 28-03-2018 SMD44_RS22955 6e8ad5b7672a7be1b14b1d455c28748a 295 Pfam PF13460 NAD(P)H-binding 6 182 8.9E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS22955 6e8ad5b7672a7be1b14b1d455c28748a 295 SUPERFAMILY SSF51735 2 183 1.92E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS22955 6e8ad5b7672a7be1b14b1d455c28748a 295 Gene3D G3DSA:3.40.50.720 1 255 2.1E-25 T 28-03-2018 SMD44_RS22955 6e8ad5b7672a7be1b14b1d455c28748a 295 SUPERFAMILY SSF51735 183 287 7.0E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 SUPERFAMILY SSF48295 555 650 3.14E-34 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 649 33.367 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 307 648 1.6E-149 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 SMART SM00760 558 627 1.1E-36 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 Gene3D G3DSA:3.40.50.300 309 476 2.5E-23 T 28-03-2018 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 Pfam PF00308 Bacterial dnaA protein 312 529 1.1E-103 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 Gene3D G3DSA:1.10.8.60 478 549 2.0E-26 T 28-03-2018 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 Gene3D G3DSA:1.10.1750.10 555 651 2.1E-36 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 561 627 6.8E-30 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 409 423 6.9E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 345 365 6.9E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 377 391 6.9E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 608 627 6.9E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 443 470 6.9E-52 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 ProSitePatterns PS01008 DnaA protein signature. 608 627 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 SUPERFAMILY SSF52540 311 523 7.71E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21120 0407849cd2ae48ec6f49f37999c71c1c 651 SMART SM00382 344 472 2.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 SUPERFAMILY SSF47413 3 49 1.25E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 2.8E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 SUPERFAMILY SSF53822 60 336 4.52E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 Gene3D G3DSA:3.40.50.2300 56 170 6.5E-25 T 28-03-2018 SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 Pfam PF13377 Periplasmic binding protein-like domain 172 334 1.6E-37 T 28-03-2018 SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 SMART SM00354 2 70 2.8E-23 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 Gene3D G3DSA:1.10.260.40 1 55 3.3E-17 T 28-03-2018 SMD44_RS05310 8efcb1e6be55db8a591fbd93e8993b63 345 Gene3D G3DSA:3.40.50.2300 171 337 1.2E-47 T 28-03-2018 SMD44_RS17440 970d3aac294c5a6fda7a9a613e177bdf 238 Gene3D G3DSA:1.10.357.10 13 228 3.0E-35 T 28-03-2018 SMD44_RS17440 970d3aac294c5a6fda7a9a613e177bdf 238 SUPERFAMILY SSF46689 15 86 5.99E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS17440 970d3aac294c5a6fda7a9a613e177bdf 238 SUPERFAMILY SSF48498 96 202 3.81E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS17440 970d3aac294c5a6fda7a9a613e177bdf 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 1.9E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS17440 970d3aac294c5a6fda7a9a613e177bdf 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS17440 970d3aac294c5a6fda7a9a613e177bdf 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 4.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS14375 bc426a5ffdfdad9402b4c8fcbba4a72b 284 SUPERFAMILY SSF47413 15 68 1.41E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS14375 bc426a5ffdfdad9402b4c8fcbba4a72b 284 Pfam PF13560 Helix-turn-helix domain 16 73 1.3E-11 T 28-03-2018 SMD44_RS14375 bc426a5ffdfdad9402b4c8fcbba4a72b 284 Gene3D G3DSA:1.10.3100.10 10 162 7.3E-13 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS14375 bc426a5ffdfdad9402b4c8fcbba4a72b 284 SMART SM00530 20 75 1.0E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS02320 5b230fe7d41e9def066cf94fecf83b33 191 SUPERFAMILY SSF48498 80 181 1.36E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS02320 5b230fe7d41e9def066cf94fecf83b33 191 Gene3D G3DSA:1.10.357.10 68 186 4.5E-19 T 28-03-2018 SMD44_RS02320 5b230fe7d41e9def066cf94fecf83b33 191 Gene3D G3DSA:1.10.10.60 1 67 5.0E-15 T 28-03-2018 SMD44_RS02320 5b230fe7d41e9def066cf94fecf83b33 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 64 1.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02320 5b230fe7d41e9def066cf94fecf83b33 191 SUPERFAMILY SSF46689 15 72 1.7E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS02320 5b230fe7d41e9def066cf94fecf83b33 191 Pfam PF16859 Bacterial transcriptional repressor C-terminal 89 180 3.4E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 SUPERFAMILY SSF50249 32 133 9.7E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 SUPERFAMILY SSF50249 210 292 3.29E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 SMART SM00316 37 108 1.9E-16 T 28-03-2018 IPR022967 RNA-binding domain, S1 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 SMART SM00316 210 280 1.3E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 SMART SM00316 124 191 6.5E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 SMART SM00316 295 366 1.1E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 Pfam PF00575 S1 RNA binding domain 36 108 5.1E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 Pfam PF00575 S1 RNA binding domain 209 280 9.8E-26 T 28-03-2018 IPR003029 S1 domain GO:0003676 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 Pfam PF00575 S1 RNA binding domain 124 191 1.1E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 Pfam PF00575 S1 RNA binding domain 294 366 3.6E-23 T 28-03-2018 IPR003029 S1 domain GO:0003676 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 Gene3D G3DSA:2.40.50.140 291 372 2.4E-25 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 Gene3D G3DSA:2.40.50.140 201 286 9.4E-27 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 Gene3D G3DSA:2.40.50.140 118 197 8.9E-12 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 SUPERFAMILY SSF50249 113 191 1.34E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 Gene3D G3DSA:2.40.50.140 16 113 1.3E-17 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 175 195 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 146 163 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 310 329 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 232 253 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 105 124 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 349 367 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 57 71 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 39 57 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 PRINTS PR00681 Ribosomal protein S1 signature 129 145 4.1E-86 T 28-03-2018 SMD44_RS10490 1306b88ade865dcbf1595632907d4972 501 SUPERFAMILY SSF50249 280 368 4.08E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS06570 3028da4301d9dd5c191648ce71a02570 591 Pfam PF00092 von Willebrand factor type A domain 388 579 6.9E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS06570 3028da4301d9dd5c191648ce71a02570 591 SUPERFAMILY SSF53850 59 339 2.17E-7 T 28-03-2018 SMD44_RS06570 3028da4301d9dd5c191648ce71a02570 591 Gene3D G3DSA:3.40.190.10 56 347 0.0034 T 28-03-2018 SMD44_RS06570 3028da4301d9dd5c191648ce71a02570 591 Pfam PF13531 Bacterial extracellular solute-binding protein 62 336 1.4E-28 T 28-03-2018 SMD44_RS06570 3028da4301d9dd5c191648ce71a02570 591 Gene3D G3DSA:3.40.50.410 384 587 6.2E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS06570 3028da4301d9dd5c191648ce71a02570 591 SMART SM00327 385 581 2.2E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS06570 3028da4301d9dd5c191648ce71a02570 591 SUPERFAMILY SSF53300 387 580 1.02E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS15295 928f5fa130c32104b64354c4d17ae0f4 560 Gene3D G3DSA:3.40.50.980 166 313 1.9E-34 T 28-03-2018 SMD44_RS15295 928f5fa130c32104b64354c4d17ae0f4 560 Pfam PF00501 AMP-binding enzyme 18 414 1.5E-63 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS15295 928f5fa130c32104b64354c4d17ae0f4 560 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS15295 928f5fa130c32104b64354c4d17ae0f4 560 Gene3D G3DSA:3.30.300.30 409 511 3.8E-13 T 28-03-2018 SMD44_RS15295 928f5fa130c32104b64354c4d17ae0f4 560 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 501 8.4E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS15295 928f5fa130c32104b64354c4d17ae0f4 560 Gene3D G3DSA:3.40.50.980 5 165 7.7E-24 T 28-03-2018 SMD44_RS15295 928f5fa130c32104b64354c4d17ae0f4 560 Gene3D G3DSA:2.30.38.10 314 408 6.6E-19 T 28-03-2018 SMD44_RS15295 928f5fa130c32104b64354c4d17ae0f4 560 SUPERFAMILY SSF56801 14 510 2.22E-98 T 28-03-2018 SMD44_RS17935 d99f8c5bb0586871144b42debdbf4700 260 SUPERFAMILY SSF54593 147 255 5.36E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS17935 d99f8c5bb0586871144b42debdbf4700 260 Gene3D G3DSA:3.10.180.10 8 129 8.6E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS17935 d99f8c5bb0586871144b42debdbf4700 260 SUPERFAMILY SSF54593 11 125 1.65E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS17935 d99f8c5bb0586871144b42debdbf4700 260 Gene3D G3DSA:3.10.180.10 136 257 1.2E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Pfam PF02310 B12 binding domain 748 864 7.0E-21 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Gene3D G3DSA:3.10.196.10 1072 1182 1.7E-39 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Gene3D G3DSA:3.10.196.10 963 1071 8.8E-30 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Pfam PF02574 Homocysteine S-methyltransferase 33 323 8.3E-60 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 SUPERFAMILY SSF82282 24 398 2.35E-102 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Pfam PF00809 Pterin binding enzyme 359 595 3.9E-45 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Gene3D G3DSA:3.40.50.280 736 885 3.8E-45 T 28-03-2018 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 SUPERFAMILY SSF52242 742 877 2.88E-38 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 TIGRFAM TIGR02082 metH: methionine synthase 29 1180 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 979 1180 5.6E-42 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Gene3D G3DSA:3.20.20.330 18 336 2.9E-85 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Pfam PF02607 B12 binding domain 663 735 3.1E-25 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 SMART SM01018 660 742 4.2E-40 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Gene3D G3DSA:1.10.1240.10 649 735 3.9E-31 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 Gene3D G3DSA:3.20.20.20 344 648 3.0E-46 T 28-03-2018 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 PIRSF PIRSF000381 18 1182 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 SUPERFAMILY SSF56507 908 1181 6.54E-94 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 SUPERFAMILY SSF51717 356 622 4.19E-72 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS08225 529a2d4cf2a43a1c60c33bb1eaf26ed8 1182 SUPERFAMILY SSF47644 660 741 2.35E-23 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS01255 5ba4bdb5100d2793b0340a9a982bd6da 508 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 224 493 3.1E-77 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 SMD44_RS01255 5ba4bdb5100d2793b0340a9a982bd6da 508 SUPERFAMILY SSF56322 210 494 8.9E-80 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS01255 5ba4bdb5100d2793b0340a9a982bd6da 508 Gene3D G3DSA:3.60.120.10 187 496 2.5E-84 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS01255 5ba4bdb5100d2793b0340a9a982bd6da 508 Pfam PF00425 chorismate binding enzyme 224 485 2.0E-66 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMD44_RS20015 db994c56f452d46943df956de7e1d658 403 Pfam PF07730 Histidine kinase 193 260 9.3E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS20015 db994c56f452d46943df956de7e1d658 403 Gene3D G3DSA:3.30.565.10 229 386 1.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20015 db994c56f452d46943df956de7e1d658 403 SUPERFAMILY SSF55874 280 378 1.48E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17125 4a42809fa954adb3ca97780c49b86d86 218 Gene3D G3DSA:3.40.50.150 4 210 2.0E-32 T 28-03-2018 SMD44_RS17125 4a42809fa954adb3ca97780c49b86d86 218 Pfam PF13649 Methyltransferase domain 54 142 7.7E-17 T 28-03-2018 SMD44_RS17125 4a42809fa954adb3ca97780c49b86d86 218 SUPERFAMILY SSF53335 3 184 5.68E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS39810 64c85d9caf05683613d26066064e7012 326 SUPERFAMILY SSF56801 2 312 1.83E-60 T 28-03-2018 SMD44_RS39810 64c85d9caf05683613d26066064e7012 326 Gene3D G3DSA:3.40.50.980 1 157 5.3E-44 T 28-03-2018 SMD44_RS39810 64c85d9caf05683613d26066064e7012 326 ProSitePatterns PS00455 Putative AMP-binding domain signature. 141 152 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS39810 64c85d9caf05683613d26066064e7012 326 Pfam PF00501 AMP-binding enzyme 2 159 7.5E-39 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS39810 64c85d9caf05683613d26066064e7012 326 Pfam PF00501 AMP-binding enzyme 222 311 3.2E-11 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS39810 64c85d9caf05683613d26066064e7012 326 Gene3D G3DSA:3.40.50.980 173 309 9.5E-17 T 28-03-2018 SMD44_RS41780 dc02b82803e29e90fa3b9d0a703a8c56 313 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 308 2.2E-115 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 SMD44_RS41780 dc02b82803e29e90fa3b9d0a703a8c56 313 Pfam PF03741 Integral membrane protein TerC family 70 272 3.3E-52 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 SMD44_RS16710 584ae0dca07172a3d530ce9b2e9e0e9e 337 Gene3D G3DSA:3.40.50.1110 66 280 6.3E-26 T 28-03-2018 SMD44_RS16710 584ae0dca07172a3d530ce9b2e9e0e9e 337 SUPERFAMILY SSF52266 71 271 2.83E-27 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS16710 584ae0dca07172a3d530ce9b2e9e0e9e 337 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 77 256 1.6E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 Gene3D G3DSA:3.40.50.720 8 152 3.8E-40 T 28-03-2018 SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.2E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.2E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.2E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 2.2E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.2E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.2E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 Gene3D G3DSA:3.40.50.720 153 239 9.2E-28 T 28-03-2018 SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 185 9.9E-6 T 28-03-2018 SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 SUPERFAMILY SSF51735 11 240 4.81E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS00190 a7cb2cd2c6b677ab0a3314dff0267ce4 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 239 3.0E-57 T 28-03-2018 SMD44_RS14875 113fcebed71e723693e312ebf4f21b5e 478 SUPERFAMILY SSF53474 368 428 1.36E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS14875 113fcebed71e723693e312ebf4f21b5e 478 SUPERFAMILY SSF53474 93 218 1.36E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS14875 113fcebed71e723693e312ebf4f21b5e 478 Gene3D G3DSA:3.40.50.1820 56 446 1.7E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS14875 113fcebed71e723693e312ebf4f21b5e 478 Pfam PF05576 PS-10 peptidase S37 40 478 7.1E-220 T 28-03-2018 IPR008761 Peptidase S37, tripeptidyl aminopeptidase SMD44_RS20750 e6bfc51f96b9296a4b6821569ab798d5 303 SMART SM00382 27 213 8.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS20750 e6bfc51f96b9296a4b6821569ab798d5 303 Gene3D G3DSA:3.40.50.300 1 243 7.9E-57 T 28-03-2018 SMD44_RS20750 e6bfc51f96b9296a4b6821569ab798d5 303 Pfam PF00005 ABC transporter 20 157 7.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS20750 e6bfc51f96b9296a4b6821569ab798d5 303 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS20750 e6bfc51f96b9296a4b6821569ab798d5 303 SUPERFAMILY SSF52540 4 216 1.33E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15315 1be8f5883afeec8f0a55152935a9f320 452 SUPERFAMILY SSF47090 280 351 1.1E-5 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS15315 1be8f5883afeec8f0a55152935a9f320 452 SUPERFAMILY SSF47090 377 451 1.96E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS15315 1be8f5883afeec8f0a55152935a9f320 452 Gene3D G3DSA:1.10.101.10 274 353 9.3E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS15315 1be8f5883afeec8f0a55152935a9f320 452 Gene3D G3DSA:1.10.101.10 375 452 2.5E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS15315 1be8f5883afeec8f0a55152935a9f320 452 SUPERFAMILY SSF54001 130 221 5.56E-9 T 28-03-2018 SMD44_RS15315 1be8f5883afeec8f0a55152935a9f320 452 Pfam PF00877 NlpC/P60 family 161 220 1.1E-4 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS15315 1be8f5883afeec8f0a55152935a9f320 452 Gene3D G3DSA:3.90.1720.10 123 266 7.2E-17 T 28-03-2018 SMD44_RS28485 0770a9706390724d68a7170172df8830 340 Pfam PF04542 Sigma-70 region 2 11 74 5.2E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28485 0770a9706390724d68a7170172df8830 340 SUPERFAMILY SSF54427 184 295 6.98E-15 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS28485 0770a9706390724d68a7170172df8830 340 Gene3D G3DSA:1.10.1740.10 3 73 1.6E-17 T 28-03-2018 SMD44_RS28485 0770a9706390724d68a7170172df8830 340 SUPERFAMILY SSF88659 112 173 4.49E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28485 0770a9706390724d68a7170172df8830 340 Gene3D G3DSA:1.10.10.10 74 163 1.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28485 0770a9706390724d68a7170172df8830 340 Gene3D G3DSA:3.10.450.50 164 299 4.0E-20 T 28-03-2018 SMD44_RS28485 0770a9706390724d68a7170172df8830 340 SUPERFAMILY SSF88946 4 90 4.32E-17 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28485 0770a9706390724d68a7170172df8830 340 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 173 6.9E-16 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 Pfam PF01839 FG-GAP repeat 408 446 1.1E-10 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 181 247 3.0E-7 T 28-03-2018 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 Gene3D G3DSA:2.130.10.130 80 258 7.3E-21 T 28-03-2018 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 PRINTS PR01185 Integrin alpha subunit signature 225 245 4.4E-6 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 PRINTS PR01185 Integrin alpha subunit signature 189 200 4.4E-6 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 PRINTS PR01185 Integrin alpha subunit signature 342 363 4.4E-6 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 Gene3D G3DSA:2.60.40.680 424 505 6.4E-18 T 28-03-2018 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 Gene3D G3DSA:2.60.40.680 306 423 8.1E-14 T 28-03-2018 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 SUPERFAMILY SSF69318 104 503 1.66E-56 T 28-03-2018 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 SMART SM00191 98 157 44.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 SMART SM00191 404 462 1.5E-6 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 SMART SM00191 169 223 0.012 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26975 fe7ac31c8c85a08ee8d0f2a410308c19 553 SMART SM00191 474 534 1.5 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 101 201 2.2E-32 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 SUPERFAMILY SSF46609 2 84 4.84E-29 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 Gene3D G3DSA:1.10.287.990 21 84 1.1E-16 T 28-03-2018 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 SUPERFAMILY SSF54719 91 206 1.22E-37 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 3.6E-29 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 168 175 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.1E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 PRINTS PR01703 Manganese superoxide dismutase signature 128 136 1.1E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 1.1E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 PRINTS PR01703 Manganese superoxide dismutase signature 166 178 1.1E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.1E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS14250 d4f6e36cf0379f09331bcc65e416cd7d 216 PIRSF PIRSF000349 1 211 3.8E-69 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMD44_RS08610 8b0535617d88b1e06e39cbcb82c16333 445 Gene3D G3DSA:1.20.1250.20 220 416 1.4E-22 T 28-03-2018 SMD44_RS08610 8b0535617d88b1e06e39cbcb82c16333 445 SUPERFAMILY SSF103473 26 414 1.26E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08610 8b0535617d88b1e06e39cbcb82c16333 445 Gene3D G3DSA:1.20.1250.20 24 205 9.4E-15 T 28-03-2018 SMD44_RS08610 8b0535617d88b1e06e39cbcb82c16333 445 Pfam PF07690 Major Facilitator Superfamily 31 274 4.1E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 Pfam PF07690 Major Facilitator Superfamily 29 421 5.0E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 SUPERFAMILY SSF103473 466 495 7.06E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 SUPERFAMILY SSF103473 18 211 7.06E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 SUPERFAMILY SSF103473 259 431 7.06E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 88 110 5.4E-11 T 28-03-2018 SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 412 431 5.4E-11 T 28-03-2018 SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 5.4E-11 T 28-03-2018 SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 5.4E-11 T 28-03-2018 SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 Gene3D G3DSA:1.20.1250.20 270 507 5.2E-21 T 28-03-2018 SMD44_RS20300 eecc19cbbb9d2344b8556f1ad0c9eedd 514 Gene3D G3DSA:1.20.1250.20 19 209 3.3E-37 T 28-03-2018 SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 Pfam PF00155 Aminotransferase class I and II 129 457 1.3E-22 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 4.0E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 4.0E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 Gene3D G3DSA:3.40.640.10 132 379 4.1E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 SUPERFAMILY SSF46785 19 74 2.82E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 SUPERFAMILY SSF53383 110 476 3.36E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 Gene3D G3DSA:1.10.10.10 8 70 9.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 Gene3D G3DSA:3.90.1150.10 380 478 1.2E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 66 7.5E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS07850 e022face6a81a551f9e40ef09465f98e 479 SMART SM00345 10 67 9.5E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 Pfam PF13365 Trypsin-like peptidase domain 75 221 3.4E-33 T 28-03-2018 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 Gene3D G3DSA:2.40.10.10 150 270 4.7E-38 T 28-03-2018 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 Pfam PF13180 PDZ domain 269 356 5.6E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 Gene3D G3DSA:2.40.10.10 45 149 1.5E-29 T 28-03-2018 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 Gene3D G3DSA:2.30.42.10 271 361 2.3E-17 T 28-03-2018 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 PRINTS PR00834 HtrA/DegQ protease family signature 84 96 9.7E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 PRINTS PR00834 HtrA/DegQ protease family signature 192 209 9.7E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 PRINTS PR00834 HtrA/DegQ protease family signature 149 173 9.7E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 PRINTS PR00834 HtrA/DegQ protease family signature 108 128 9.7E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 PRINTS PR00834 HtrA/DegQ protease family signature 214 231 9.7E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 PRINTS PR00834 HtrA/DegQ protease family signature 307 319 9.7E-43 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 SMART SM00228 269 349 1.0E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 SUPERFAMILY SSF50156 250 357 6.44E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS27870 4b3356f5e59f588a50f086ce469780e7 364 SUPERFAMILY SSF50494 49 275 2.11E-54 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS17090 e9c11d1b109741f35219afdd80494868 304 SUPERFAMILY SSF53790 22 242 6.41E-74 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS17090 e9c11d1b109741f35219afdd80494868 304 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 23 226 1.8E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS17090 e9c11d1b109741f35219afdd80494868 304 PIRSF PIRSF005917 13 300 1.6E-89 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS17090 e9c11d1b109741f35219afdd80494868 304 Gene3D G3DSA:3.40.1010.10 21 133 9.7E-32 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS17090 e9c11d1b109741f35219afdd80494868 304 Gene3D G3DSA:3.30.950.10 134 247 1.2E-42 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS17090 e9c11d1b109741f35219afdd80494868 304 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 25 292 2.1E-58 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS17090 e9c11d1b109741f35219afdd80494868 304 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 23 244 33.021 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS07485 148cf13dd47509dc2b9fb114a60b5401 388 Gene3D G3DSA:3.40.50.2000 175 358 3.5E-44 T 28-03-2018 SMD44_RS07485 148cf13dd47509dc2b9fb114a60b5401 388 Pfam PF13439 Glycosyltransferase Family 4 14 173 7.7E-34 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS07485 148cf13dd47509dc2b9fb114a60b5401 388 SUPERFAMILY SSF53756 2 363 3.14E-86 T 28-03-2018 SMD44_RS07485 148cf13dd47509dc2b9fb114a60b5401 388 Gene3D G3DSA:3.40.50.2000 3 174 2.8E-18 T 28-03-2018 SMD44_RS07485 148cf13dd47509dc2b9fb114a60b5401 388 Pfam PF13692 Glycosyl transferases group 1 187 328 1.1E-30 T 28-03-2018 SMD44_RS43490 9ba3195827e71cd0ce6401c7f02501e3 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 24 121 1.0E-26 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD44_RS00590 607483b2ae490f36e87d08907a062770 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 8.7E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00590 607483b2ae490f36e87d08907a062770 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 8.7E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00590 607483b2ae490f36e87d08907a062770 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 8.7E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00590 607483b2ae490f36e87d08907a062770 280 SUPERFAMILY SSF46955 12 113 1.94E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS00590 607483b2ae490f36e87d08907a062770 280 SMART SM00422 11 80 4.9E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00590 607483b2ae490f36e87d08907a062770 280 Gene3D G3DSA:1.10.1660.10 8 66 4.6E-17 T 28-03-2018 SMD44_RS00590 607483b2ae490f36e87d08907a062770 280 Gene3D G3DSA:1.10.1660.10 67 131 5.8E-9 T 28-03-2018 SMD44_RS00590 607483b2ae490f36e87d08907a062770 280 Pfam PF00376 MerR family regulatory protein 12 49 9.6E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00415 fe4f2d69cfb1d9e7e566a95319f8acb3 106 Gene3D G3DSA:2.60.20.10 12 104 1.4E-4 T 28-03-2018 SMD44_RS00415 fe4f2d69cfb1d9e7e566a95319f8acb3 106 Pfam PF03995 Peptidase inhibitor family I36 14 87 8.7E-16 T 28-03-2018 SMD44_RS19965 682703f57c98f2fa3ae9c1150db64157 286 Pfam PF01551 Peptidase family M23 135 243 1.7E-16 T 28-03-2018 IPR016047 Peptidase M23 SMD44_RS19965 682703f57c98f2fa3ae9c1150db64157 286 Gene3D G3DSA:2.70.70.10 66 283 2.2E-33 T 28-03-2018 SMD44_RS19965 682703f57c98f2fa3ae9c1150db64157 286 SUPERFAMILY SSF51261 180 244 1.46E-21 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS19965 682703f57c98f2fa3ae9c1150db64157 286 SUPERFAMILY SSF51261 133 149 1.46E-21 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS18340 5303400e3fa2f8094477b59b9b29db9d 382 Pfam PF00005 ABC transporter 63 206 1.6E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS18340 5303400e3fa2f8094477b59b9b29db9d 382 SMART SM00382 72 255 1.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS18340 5303400e3fa2f8094477b59b9b29db9d 382 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 55 352 6.4E-102 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD44_RS18340 5303400e3fa2f8094477b59b9b29db9d 382 ProSitePatterns PS00211 ABC transporters family signature. 179 193 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS18340 5303400e3fa2f8094477b59b9b29db9d 382 Gene3D G3DSA:3.40.50.300 45 290 1.1E-55 T 28-03-2018 SMD44_RS18340 5303400e3fa2f8094477b59b9b29db9d 382 SUPERFAMILY SSF52540 43 267 5.84E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18340 5303400e3fa2f8094477b59b9b29db9d 382 Gene3D G3DSA:3.30.70.260 301 376 0.0012 T 28-03-2018 SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 Gene3D G3DSA:1.10.1740.10 17 85 8.7E-15 T 28-03-2018 SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 SUPERFAMILY SSF88946 20 101 1.8E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 SUPERFAMILY SSF54427 197 310 7.75E-12 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 Gene3D G3DSA:3.10.450.50 177 310 2.5E-18 T 28-03-2018 SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 Pfam PF04542 Sigma-70 region 2 20 85 1.8E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 Pfam PF08281 Sigma-70, region 4 133 183 4.2E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 SUPERFAMILY SSF88659 127 186 5.61E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 Gene3D G3DSA:1.10.10.10 86 176 2.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS41110 9676ebcb8d2e7e353e1d2ca84222260e 325 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 186 8.4E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Gene3D G3DSA:1.10.150.20 510 581 1.0E-14 T 28-03-2018 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 SUPERFAMILY SSF56091 13 326 2.56E-71 T 28-03-2018 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Gene3D G3DSA:3.30.1490.70 226 330 8.2E-18 T 28-03-2018 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 SMART SM00292 601 686 7.7E-6 T 28-03-2018 IPR001357 BRCT domain SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 13 326 5.2E-67 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 SUPERFAMILY SSF52113 603 683 3.05E-8 T 28-03-2018 IPR001357 BRCT domain SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 601 682 1.5E-4 T 28-03-2018 IPR001357 BRCT domain SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Gene3D G3DSA:3.40.50.10190 582 685 6.4E-12 T 28-03-2018 IPR001357 BRCT domain SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Gene3D G3DSA:2.40.50.140 331 399 2.6E-29 T 28-03-2018 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 PIRSF PIRSF001604 7 686 3.1E-169 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Pfam PF12826 Helix-hairpin-helix motif 514 566 6.4E-9 T 28-03-2018 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 23 679 2.7E-155 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Gene3D G3DSA:3.30.1490.70 88 171 2.0E-8 T 28-03-2018 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Hamap MF_01588 DNA ligase [ligA]. 13 683 41.14 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 SMART SM00532 11 453 2.6E-123 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Gene3D G3DSA:1.10.287.610 6 75 6.7E-16 T 28-03-2018 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 SUPERFAMILY SSF50249 328 408 2.23E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 331 407 7.5E-31 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 SUPERFAMILY SSF47781 413 585 3.52E-31 T 28-03-2018 IPR010994 RuvA domain 2-like SMD44_RS42330 817f61fd058d16b3baf4187956750025 688 Gene3D G3DSA:1.10.150.20 440 509 5.5E-11 T 28-03-2018 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 PIRSF PIRSF000171 1 579 3.2E-50 T 28-03-2018 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 SUPERFAMILY SSF51905 2 259 6.89E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 SUPERFAMILY SSF51905 358 431 6.89E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 SUPERFAMILY SSF56425 236 354 1.03E-42 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 Gene3D G3DSA:1.20.58.100 425 535 1.0E-37 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 Pfam PF00890 FAD binding domain 7 400 6.2E-112 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 6.8E-278 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 Gene3D G3DSA:3.50.50.60 3 293 7.6E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 584 1.1E-46 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 Gene3D G3DSA:4.10.80.40 536 584 1.6E-19 T 28-03-2018 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 Gene3D G3DSA:3.50.50.60 303 416 1.3E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 1.4E-247 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 2.4E-5 T 28-03-2018 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.4E-5 T 28-03-2018 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 7.2E-6 T 28-03-2018 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 7.2E-6 T 28-03-2018 SMD44_RS26575 d74ee534209f56c0f619da714f616b5b 584 SUPERFAMILY SSF46977 446 584 1.96E-52 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS01385 bedfc5023a8fcadd574cd63dd1697dec 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 94 1.4E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS01385 bedfc5023a8fcadd574cd63dd1697dec 314 SUPERFAMILY SSF51735 122 245 3.24E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01385 bedfc5023a8fcadd574cd63dd1697dec 314 Gene3D G3DSA:3.90.180.10 196 314 4.3E-5 T 28-03-2018 SMD44_RS01385 bedfc5023a8fcadd574cd63dd1697dec 314 Pfam PF13602 Zinc-binding dehydrogenase 191 311 3.7E-10 T 28-03-2018 SMD44_RS01385 bedfc5023a8fcadd574cd63dd1697dec 314 Gene3D G3DSA:3.90.180.10 1 195 6.1E-48 T 28-03-2018 SMD44_RS01385 bedfc5023a8fcadd574cd63dd1697dec 314 SMART SM00829 10 311 3.5E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS01385 bedfc5023a8fcadd574cd63dd1697dec 314 SUPERFAMILY SSF50129 1 155 1.34E-35 T 28-03-2018 IPR011032 GroES-like SMD44_RS29695 ea1553f9afc587b5973a56f144651459 591 Gene3D G3DSA:3.90.76.10 70 236 2.8E-30 T 28-03-2018 SMD44_RS29695 ea1553f9afc587b5973a56f144651459 591 PIRSF PIRSF002741 7 584 1.9E-64 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS29695 ea1553f9afc587b5973a56f144651459 591 Gene3D G3DSA:3.10.105.10 339 558 3.8E-42 T 28-03-2018 SMD44_RS29695 ea1553f9afc587b5973a56f144651459 591 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 106 498 6.5E-71 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS29695 ea1553f9afc587b5973a56f144651459 591 SUPERFAMILY SSF53850 58 583 1.5E-93 T 28-03-2018 SMD44_RS29695 ea1553f9afc587b5973a56f144651459 591 Gene3D G3DSA:3.40.190.10 237 338 4.1E-14 T 28-03-2018 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 Gene3D G3DSA:1.25.40.10 1018 1118 1.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 Gene3D G3DSA:1.10.10.10 3 92 5.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 SMART SM00862 12 84 1.3E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 Gene3D G3DSA:3.40.50.300 327 489 3.1E-13 T 28-03-2018 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 SUPERFAMILY SSF52540 331 617 1.6E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 SMART SM01043 91 235 7.9E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 Gene3D G3DSA:1.25.40.10 93 286 1.0E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 PRINTS PR00364 Disease resistance protein signature 362 377 6.3E-5 T 28-03-2018 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 PRINTS PR00364 Disease resistance protein signature 445 459 6.3E-5 T 28-03-2018 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 PRINTS PR00364 Disease resistance protein signature 551 565 6.3E-5 T 28-03-2018 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 Pfam PF00486 Transcriptional regulatory protein, C terminal 21 72 2.3E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 SUPERFAMILY SSF46894 2 84 1.33E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 SUPERFAMILY SSF48452 86 240 4.17E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 Pfam PF03704 Bacterial transcriptional activator domain 91 235 2.0E-37 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 Gene3D G3DSA:1.25.40.10 894 1017 3.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS33650 1be4d552b50df14cd3be121c8a6ea045 1136 SUPERFAMILY SSF48452 885 1010 1.73E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS42530 4c8f689087b7844cecaf1ce62a978569 285 Gene3D G3DSA:3.40.640.10 1 151 5.5E-19 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS42530 4c8f689087b7844cecaf1ce62a978569 285 SUPERFAMILY SSF53383 3 236 1.53E-33 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS42530 4c8f689087b7844cecaf1ce62a978569 285 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 117 130 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMD44_RS42530 4c8f689087b7844cecaf1ce62a978569 285 Gene3D G3DSA:3.90.1150.10 152 262 8.4E-7 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS42530 4c8f689087b7844cecaf1ce62a978569 285 Pfam PF00155 Aminotransferase class I and II 42 243 7.7E-18 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 Gene3D G3DSA:1.10.8.50 1 67 5.4E-22 T 28-03-2018 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.1E-50 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 Gene3D G3DSA:4.10.910.10 87 122 7.2E-25 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 SUPERFAMILY SSF46946 2 122 3.83E-43 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.703 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 Gene3D G3DSA:4.10.910.10 68 86 5.3E-15 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.4E-31 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25630 e6e4f1da261adf4f73441a1289d6d981 126 PIRSF PIRSF002134 1 125 4.6E-42 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS09210 37c92135dd4586710ff8bfcf72d80a16 276 Pfam PF08021 Siderophore-interacting FAD-binding domain 12 136 4.8E-36 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SMD44_RS09210 37c92135dd4586710ff8bfcf72d80a16 276 Pfam PF04954 Siderophore-interacting protein 152 263 3.4E-38 T 28-03-2018 IPR007037 Siderophore-interacting protein SMD44_RS09210 37c92135dd4586710ff8bfcf72d80a16 276 Gene3D G3DSA:3.40.50.80 146 276 3.1E-46 T 28-03-2018 SMD44_RS09210 37c92135dd4586710ff8bfcf72d80a16 276 Gene3D G3DSA:2.40.30.10 1 138 4.2E-33 T 28-03-2018 SMD44_RS09210 37c92135dd4586710ff8bfcf72d80a16 276 SUPERFAMILY SSF63380 5 138 1.54E-9 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS13405 551964b97890f2ba128f6ed1c55df9a6 213 Pfam PF04203 Sortase family 70 209 3.7E-17 T 28-03-2018 IPR005754 Sortase family SMD44_RS13405 551964b97890f2ba128f6ed1c55df9a6 213 SUPERFAMILY SSF63817 62 210 4.51E-15 T 28-03-2018 IPR023365 Sortase domain SMD44_RS13405 551964b97890f2ba128f6ed1c55df9a6 213 Gene3D G3DSA:2.40.260.10 30 213 6.2E-29 T 28-03-2018 IPR023365 Sortase domain SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PIRSF PIRSF000532 1 339 4.2E-117 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.285 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 Pfam PF00365 Phosphofructokinase 2 297 2.7E-104 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 SUPERFAMILY SSF53784 1 332 7.32E-121 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 3.6E-74 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 Gene3D G3DSA:3.40.50.450 1 219 2.4E-78 T 28-03-2018 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 4.3E-148 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS05605 2eaa207d424acd497c6a3d7b460c9e69 341 Gene3D G3DSA:3.40.50.450 220 332 6.7E-10 T 28-03-2018 SMD44_RS28875 ea09d84dd3317b180efc100ab8e2f060 182 Pfam PF00430 ATP synthase B/B' CF(0) 25 153 2.3E-27 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMD44_RS28875 ea09d84dd3317b180efc100ab8e2f060 182 SUPERFAMILY SSF81573 80 138 9.81E-10 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD44_RS28875 ea09d84dd3317b180efc100ab8e2f060 182 Hamap MF_01398 ATP synthase subunit b [atpF]. 17 155 12.106 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMD44_RS28875 ea09d84dd3317b180efc100ab8e2f060 182 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 28 174 3.7E-26 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 SMD44_RS28875 ea09d84dd3317b180efc100ab8e2f060 182 Gene3D G3DSA:1.20.5.620 79 139 2.6E-9 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 Gene3D G3DSA:3.40.190.10 91 172 7.1E-16 T 28-03-2018 SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 Gene3D G3DSA:3.40.190.10 173 265 4.6E-19 T 28-03-2018 SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 SUPERFAMILY SSF46785 2 86 9.16E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 SUPERFAMILY SSF53850 102 290 1.38E-29 T 28-03-2018 SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 Gene3D G3DSA:1.10.10.10 1 90 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 Pfam PF03466 LysR substrate binding domain 100 289 1.0E-34 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS38580 a0255c3fddf88e31cadd47cf4c8c8ea0 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS11660 976cb7caeaa9b8a916e64f7b4338ae25 167 SUPERFAMILY SSF53927 5 155 1.2E-36 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMD44_RS11660 976cb7caeaa9b8a916e64f7b4338ae25 167 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 106 5.4E-20 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SMD44_RS11660 976cb7caeaa9b8a916e64f7b4338ae25 167 Gene3D G3DSA:3.40.140.10 2 161 2.9E-32 T 28-03-2018 SMD44_RS36325 b8770ab6de3400ab05a9e0d60599a6cf 375 Gene3D G3DSA:3.30.420.40 204 368 8.7E-34 T 28-03-2018 SMD44_RS36325 b8770ab6de3400ab05a9e0d60599a6cf 375 Gene3D G3DSA:3.30.420.40 76 203 1.8E-21 T 28-03-2018 SMD44_RS36325 b8770ab6de3400ab05a9e0d60599a6cf 375 SUPERFAMILY SSF46785 14 78 9.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36325 b8770ab6de3400ab05a9e0d60599a6cf 375 Pfam PF00480 ROK family 87 357 1.6E-19 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS36325 b8770ab6de3400ab05a9e0d60599a6cf 375 Pfam PF12802 MarR family 21 65 9.7E-8 T 28-03-2018 SMD44_RS36325 b8770ab6de3400ab05a9e0d60599a6cf 375 Gene3D G3DSA:1.10.10.10 19 75 4.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36325 b8770ab6de3400ab05a9e0d60599a6cf 375 SUPERFAMILY SSF53067 84 367 1.14E-36 T 28-03-2018 SMD44_RS17405 105237c50798617940517da460f91c6b 253 SMART SM01134 73 234 1.4E-63 T 28-03-2018 SMD44_RS17405 105237c50798617940517da460f91c6b 253 Gene3D G3DSA:1.10.10.10 1 63 4.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17405 105237c50798617940517da460f91c6b 253 Pfam PF00455 DeoR C terminal sensor domain 76 233 1.4E-47 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain SMD44_RS17405 105237c50798617940517da460f91c6b 253 SUPERFAMILY SSF46785 5 58 1.08E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17405 105237c50798617940517da460f91c6b 253 SUPERFAMILY SSF100950 76 236 4.92E-25 T 28-03-2018 SMD44_RS17405 105237c50798617940517da460f91c6b 253 Gene3D G3DSA:3.40.50.1360 73 239 3.4E-38 T 28-03-2018 SMD44_RS17405 105237c50798617940517da460f91c6b 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.1E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS17405 105237c50798617940517da460f91c6b 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.1E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS17405 105237c50798617940517da460f91c6b 253 SMART SM00420 6 58 7.5E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS17405 105237c50798617940517da460f91c6b 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 5.7E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS26480 a5a86ab1b9c99290e6266f070b3c5277 428 Gene3D G3DSA:3.60.21.10 206 425 1.0E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS26480 a5a86ab1b9c99290e6266f070b3c5277 428 Pfam PF00149 Calcineurin-like phosphoesterase 208 368 5.0E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS26480 a5a86ab1b9c99290e6266f070b3c5277 428 SUPERFAMILY SSF56300 205 425 9.56E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS41710 9b4a17f357512c22e3fe3fe8001e2906 327 SMART SM00382 20 222 2.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS41710 9b4a17f357512c22e3fe3fe8001e2906 327 Gene3D G3DSA:3.40.50.300 1 141 9.6E-12 T 28-03-2018 SMD44_RS41710 9b4a17f357512c22e3fe3fe8001e2906 327 SUPERFAMILY SSF52540 4 217 4.73E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS41710 9b4a17f357512c22e3fe3fe8001e2906 327 Pfam PF13191 AAA ATPase domain 4 122 6.2E-9 T 28-03-2018 SMD44_RS06885 d9534a9701a8903cefda053a10f7c1d7 124 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 120 26.567 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMD44_RS06885 d9534a9701a8903cefda053a10f7c1d7 124 Pfam PF13397 RNA polymerase-binding protein 4 107 7.4E-42 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMD44_RS11035 89677c6e712e94dca4fb71122c812c90 437 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 364 388 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SMD44_RS11035 89677c6e712e94dca4fb71122c812c90 437 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 49 405 4.8E-116 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 SMD44_RS11035 89677c6e712e94dca4fb71122c812c90 437 Pfam PF01098 Cell cycle protein 50 405 2.7E-95 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 Gene3D G3DSA:3.40.1190.20 2 301 2.2E-78 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 241 254 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 Pfam PF00294 pfkB family carbohydrate kinase 5 289 4.1E-68 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 Hamap MF_01987 Ribokinase [rbsK]. 4 296 27.271 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 PRINTS PR00990 Ribokinase signature 211 222 5.6E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 PRINTS PR00990 Ribokinase signature 106 119 5.6E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 PRINTS PR00990 Ribokinase signature 173 188 5.6E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 PRINTS PR00990 Ribokinase signature 8 29 5.6E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 PRINTS PR00990 Ribokinase signature 35 54 5.6E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 SUPERFAMILY SSF53613 1 292 5.77E-81 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS10740 8b1b4a071618bb8fcf60457e424a7891 301 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 6 294 3.6E-98 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 SMD44_RS35970 8b0568f5a6834f1e262fced176024ef0 299 Gene3D G3DSA:3.40.190.10 89 181 1.2E-19 T 28-03-2018 SMD44_RS35970 8b0568f5a6834f1e262fced176024ef0 299 SUPERFAMILY SSF46785 2 111 3.19E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35970 8b0568f5a6834f1e262fced176024ef0 299 Pfam PF03466 LysR substrate binding domain 88 297 5.3E-37 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS35970 8b0568f5a6834f1e262fced176024ef0 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS35970 8b0568f5a6834f1e262fced176024ef0 299 Gene3D G3DSA:1.10.10.10 1 87 7.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35970 8b0568f5a6834f1e262fced176024ef0 299 SUPERFAMILY SSF53850 89 296 5.97E-34 T 28-03-2018 SMD44_RS35970 8b0568f5a6834f1e262fced176024ef0 299 Gene3D G3DSA:3.40.190.10 182 272 1.2E-24 T 28-03-2018 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 220 237 8.4E-48 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 141 155 8.4E-48 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 240 263 8.4E-48 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 264 278 8.4E-48 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 199 219 8.4E-48 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 Gene3D G3DSA:2.40.10.10 199 286 4.2E-21 T 28-03-2018 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 Gene3D G3DSA:2.40.10.10 115 198 8.7E-22 T 28-03-2018 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 PIRSF PIRSF001134 10 299 6.7E-96 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 Pfam PF02983 Alpha-lytic protease prodomain 44 98 3.5E-11 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 SUPERFAMILY SSF50494 122 293 3.81E-38 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 Pfam PF00089 Trypsin 115 290 5.1E-11 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 143 148 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 249 260 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS08905 9b6a5c2efd777293f72b7b9d7d670378 299 Gene3D G3DSA:3.30.300.50 20 109 4.7E-18 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS28900 76f51b5e387a7a7d61657358bfd363a9 124 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 1.4E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28900 76f51b5e387a7a7d61657358bfd363a9 124 Gene3D G3DSA:2.60.15.10 1 90 2.9E-25 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28900 76f51b5e387a7a7d61657358bfd363a9 124 SUPERFAMILY SSF51344 5 85 5.62E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28900 76f51b5e387a7a7d61657358bfd363a9 124 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 18 90 1.0E-33 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28900 76f51b5e387a7a7d61657358bfd363a9 124 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 115 1.9E-26 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28900 76f51b5e387a7a7d61657358bfd363a9 124 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 123 18.801 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 Gene3D G3DSA:2.30.130.10 282 374 4.2E-27 T 28-03-2018 IPR002478 PUA domain GO:0003723 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 Pfam PF01472 PUA domain 284 358 1.0E-17 T 28-03-2018 IPR002478 PUA domain GO:0003723 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 Gene3D G3DSA:3.40.1160.10 2 272 6.3E-59 T 28-03-2018 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 Hamap MF_00456 Glutamate 5-kinase [proB]. 14 266 34.962 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 PRINTS PR00474 Glutamate 5-kinase family signature 86 114 4.6E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 4.6E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 4.6E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 PRINTS PR00474 Glutamate 5-kinase family signature 52 66 4.6E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 PRINTS PR00474 Glutamate 5-kinase family signature 219 239 4.6E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 SUPERFAMILY SSF53633 15 264 4.06E-61 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 TIGRFAM TIGR01027 proB: glutamate 5-kinase 15 373 1.1E-123 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 ProSitePatterns PS00902 Glutamate 5-kinase signature. 217 234 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 SMART SM00359 284 363 1.4E-16 T 28-03-2018 IPR002478 PUA domain GO:0003723 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 PIRSF PIRSF000729 9 376 3.2E-120 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 Pfam PF00696 Amino acid kinase family 15 245 1.8E-39 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMD44_RS13985 1e9febc74015fe9092436e0c292b7999 377 SUPERFAMILY SSF88697 284 374 7.73E-21 T 28-03-2018 IPR015947 PUA-like domain SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 SMART SM00191 348 408 1.5E-8 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 SMART SM00191 48 104 25.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 Gene3D G3DSA:2.130.10.130 148 258 2.3E-7 T 28-03-2018 SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 58 139 3.0E-6 T 28-03-2018 SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 Gene3D G3DSA:2.60.40.680 14 147 6.1E-14 T 28-03-2018 SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 Gene3D G3DSA:2.60.40.680 283 368 8.0E-18 T 28-03-2018 SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 Gene3D G3DSA:2.60.40.680 369 451 1.7E-8 T 28-03-2018 SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 SUPERFAMILY SSF69318 57 449 1.83E-49 T 28-03-2018 SMD44_RS18460 7351d4266e9c5858782324cae478d0c5 493 Pfam PF01839 FG-GAP repeat 352 392 5.4E-9 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS14525 0a3e732d9b85e5213388937f5ad2f7fd 134 Pfam PF01152 Bacterial-like globin 13 129 1.0E-34 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 SMD44_RS14525 0a3e732d9b85e5213388937f5ad2f7fd 134 Gene3D G3DSA:1.10.490.10 9 134 8.5E-36 T 28-03-2018 SMD44_RS14525 0a3e732d9b85e5213388937f5ad2f7fd 134 SUPERFAMILY SSF46458 12 133 1.19E-37 T 28-03-2018 IPR009050 Globin-like SMD44_RS14230 5e49d832b820cbf45fab3892550aec59 445 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 23 56 - T 28-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 SMD44_RS14230 5e49d832b820cbf45fab3892550aec59 445 Gene3D G3DSA:3.30.465.10 73 211 5.7E-33 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS14230 5e49d832b820cbf45fab3892550aec59 445 Gene3D G3DSA:3.30.43.10 1 72 2.2E-13 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD44_RS14230 5e49d832b820cbf45fab3892550aec59 445 SUPERFAMILY SSF56176 15 187 6.54E-43 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS14230 5e49d832b820cbf45fab3892550aec59 445 Pfam PF01565 FAD binding domain 23 155 1.4E-26 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD44_RS30560 4d8d406f94bc810f777adaf758e8d7c7 223 SUPERFAMILY SSF51261 57 181 1.31E-11 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS30560 4d8d406f94bc810f777adaf758e8d7c7 223 Gene3D G3DSA:2.70.70.10 47 191 2.0E-18 T 28-03-2018 SMD44_RS30560 4d8d406f94bc810f777adaf758e8d7c7 223 Pfam PF01551 Peptidase family M23 79 177 1.1E-11 T 28-03-2018 IPR016047 Peptidase M23 SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 Gene3D G3DSA:2.40.50.140 1 66 1.4E-28 T 28-03-2018 SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 SUPERFAMILY SSF50249 1 64 1.04E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 PIRSF PIRSF002599 1 67 9.2E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 6.3E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS18795 1fa556da29ec41ebd632ba56ac93bf54 67 SMART SM00357 3 66 1.4E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SMD44_RS31240 aa41fabe3461e2685fb323ba3afdc913 143 Pfam PF00581 Rhodanese-like domain 39 138 3.2E-9 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31240 aa41fabe3461e2685fb323ba3afdc913 143 SMART SM00450 36 141 1.1E-15 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31240 aa41fabe3461e2685fb323ba3afdc913 143 SUPERFAMILY SSF52821 27 143 1.44E-20 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31240 aa41fabe3461e2685fb323ba3afdc913 143 Gene3D G3DSA:3.40.250.10 15 143 8.0E-20 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 Gene3D G3DSA:1.20.1250.20 11 213 1.7E-33 T 28-03-2018 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 Gene3D G3DSA:1.20.1250.20 271 525 8.0E-33 T 28-03-2018 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 Pfam PF07690 Major Facilitator Superfamily 27 423 5.1E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 433 6.9E-77 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 SUPERFAMILY SSF103473 485 514 5.1E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 SUPERFAMILY SSF103473 8 210 5.1E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 SUPERFAMILY SSF103473 262 433 5.1E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 414 433 1.9E-10 T 28-03-2018 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 1.9E-10 T 28-03-2018 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 372 392 1.9E-10 T 28-03-2018 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 176 200 1.9E-10 T 28-03-2018 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 31 55 1.9E-10 T 28-03-2018 SMD44_RS11965 b00879c7992712fd936f81b3a1e2ebe1 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 90 112 1.9E-10 T 28-03-2018 SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 88 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 1.8E-6 T 28-03-2018 SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 209 227 1.8E-6 T 28-03-2018 SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 1.8E-6 T 28-03-2018 SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 Pfam PF07690 Major Facilitator Superfamily 22 417 7.4E-57 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 SUPERFAMILY SSF103473 457 480 7.06E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 SUPERFAMILY SSF103473 254 428 7.06E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 SUPERFAMILY SSF103473 10 202 7.06E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 Gene3D G3DSA:1.20.1250.20 265 494 2.1E-24 T 28-03-2018 SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 454 4.1E-80 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS17435 c477b27c837566d953bc6e698543e43c 509 Gene3D G3DSA:1.20.1250.20 12 204 2.2E-36 T 28-03-2018 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 Pfam PF00210 Ferritin-like domain 8 143 4.3E-32 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 Gene3D G3DSA:1.20.1260.10 1 75 9.0E-17 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 7.4E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 SUPERFAMILY SSF47240 1 155 5.88E-46 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 Gene3D G3DSA:1.20.5.420 85 138 6.9E-16 T 28-03-2018 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 PRINTS PR00601 Bacterioferritin signature 23 43 1.6E-55 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 PRINTS PR00601 Bacterioferritin signature 3 22 1.6E-55 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 PRINTS PR00601 Bacterioferritin signature 86 106 1.6E-55 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 PRINTS PR00601 Bacterioferritin signature 107 127 1.6E-55 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 PRINTS PR00601 Bacterioferritin signature 128 149 1.6E-55 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 PRINTS PR00601 Bacterioferritin signature 44 64 1.6E-55 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 PRINTS PR00601 Bacterioferritin signature 65 85 1.6E-55 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS11190 225778cd1ed755e3605fe770b3dcb4d6 159 PIRSF PIRSF002560 1 157 1.2E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 SUPERFAMILY SSF48179 210 308 5.95E-26 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 303 3.7E-30 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 425 6.5E-126 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 PIRSF PIRSF000124 3 444 2.0E-116 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 192 2.9E-59 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 Gene3D G3DSA:1.20.5.100 210 232 1.0E-12 T 28-03-2018 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 SUPERFAMILY SSF51735 4 196 6.04E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 SMART SM00984 328 429 1.6E-43 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 SUPERFAMILY SSF52413 320 439 1.44E-34 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 PIRSF PIRSF500134 3 447 4.9E-156 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 Gene3D G3DSA:3.40.50.720 233 441 7.0E-64 T 28-03-2018 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 Gene3D G3DSA:3.40.50.720 1 206 4.2E-55 T 28-03-2018 SMD44_RS16525 76f12d1a4b94c9d1e57d781fe349e0d1 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 328 429 2.4E-25 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD44_RS15480 df9cc21bbcfffc2f7706b5473a142fab 365 SUPERFAMILY SSF48452 25 133 2.74E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS15480 df9cc21bbcfffc2f7706b5473a142fab 365 Gene3D G3DSA:1.25.40.10 11 339 2.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS09215 827c4d84cea3ca39daeecea00ca05109 350 SUPERFAMILY SSF56784 27 279 5.03E-53 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS09215 827c4d84cea3ca39daeecea00ca05109 350 Pfam PF13242 HAD-hyrolase-like 208 278 6.5E-16 T 28-03-2018 SMD44_RS09215 827c4d84cea3ca39daeecea00ca05109 350 Gene3D G3DSA:3.40.50.1000 26 110 1.6E-4 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS09215 827c4d84cea3ca39daeecea00ca05109 350 PIRSF PIRSF000915 9 284 1.6E-54 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD44_RS09215 827c4d84cea3ca39daeecea00ca05109 350 Gene3D G3DSA:3.40.50.1000 111 208 3.6E-26 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS09215 827c4d84cea3ca39daeecea00ca05109 350 Pfam PF13344 Haloacid dehalogenase-like hydrolase 32 132 6.9E-22 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD44_RS06020 9109c75801f2530a15c67979f04a27af 412 Gene3D G3DSA:3.30.565.10 204 412 3.7E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06020 9109c75801f2530a15c67979f04a27af 412 SUPERFAMILY SSF55874 297 411 4.17E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06020 9109c75801f2530a15c67979f04a27af 412 Pfam PF07730 Histidine kinase 218 281 2.3E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS10175 458a0ee397289311b85209842c1e70c8 308 Pfam PF00294 pfkB family carbohydrate kinase 2 296 3.1E-43 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS10175 458a0ee397289311b85209842c1e70c8 308 Gene3D G3DSA:3.40.1190.20 1 303 7.9E-60 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS10175 458a0ee397289311b85209842c1e70c8 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 239 252 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD44_RS10175 458a0ee397289311b85209842c1e70c8 308 SUPERFAMILY SSF53613 2 299 4.37E-62 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 SUPERFAMILY SSF52172 2 118 6.97E-27 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 SMART SM00448 1 104 2.3E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 SUPERFAMILY SSF46894 113 190 5.1E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 SMART SM00421 127 184 8.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 Pfam PF00196 Bacterial regulatory proteins, luxR family 129 183 5.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 Gene3D G3DSA:3.40.50.2300 1 115 4.3E-29 T 28-03-2018 SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 Gene3D G3DSA:1.10.10.10 116 190 4.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 160 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 130 144 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 172 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27780 79b31d0215bd3076c2d5049e8986df13 190 Pfam PF00072 Response regulator receiver domain 2 104 1.1E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18510 f155c4be1afab88e404f937531fa3582 196 Pfam PF02834 LigT like Phosphoesterase 98 170 2.5E-8 T 28-03-2018 IPR014051 Phosphoesterase, HXTX SMD44_RS18510 f155c4be1afab88e404f937531fa3582 196 Pfam PF02834 LigT like Phosphoesterase 9 86 1.4E-16 T 28-03-2018 IPR014051 Phosphoesterase, HXTX SMD44_RS18510 f155c4be1afab88e404f937531fa3582 196 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 183 1.6E-32 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 SMD44_RS18510 f155c4be1afab88e404f937531fa3582 196 Gene3D G3DSA:3.90.1140.10 1 195 1.0E-43 T 28-03-2018 SMD44_RS18510 f155c4be1afab88e404f937531fa3582 196 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 185 22.918 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 SMD44_RS18510 f155c4be1afab88e404f937531fa3582 196 SUPERFAMILY SSF55144 1 187 2.44E-39 T 28-03-2018 IPR009097 Cyclic phosphodiesterase SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 SUPERFAMILY SSF53649 37 458 6.67E-120 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 Gene3D G3DSA:3.40.720.10 13 459 3.9E-112 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 SMART SM00098 50 459 1.6E-164 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 Pfam PF00245 Alkaline phosphatase 49 412 1.6E-109 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 PRINTS PR00113 Alkaline phosphatase signature 307 336 1.3E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 PRINTS PR00113 Alkaline phosphatase signature 104 119 1.3E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 PRINTS PR00113 Alkaline phosphatase signature 204 214 1.3E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 PRINTS PR00113 Alkaline phosphatase signature 49 69 1.3E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD44_RS22320 42eba8dd2a818574fd16ac68f74eaf04 459 PRINTS PR00113 Alkaline phosphatase signature 142 162 1.3E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD44_RS05050 5162e01e9a355d78f0fdc910be489899 538 Gene3D G3DSA:3.40.50.2300 185 310 2.6E-33 T 28-03-2018 SMD44_RS05050 5162e01e9a355d78f0fdc910be489899 538 Pfam PF00486 Transcriptional regulatory protein, C terminal 339 413 2.6E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS05050 5162e01e9a355d78f0fdc910be489899 538 SUPERFAMILY SSF46894 318 414 1.62E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS05050 5162e01e9a355d78f0fdc910be489899 538 SMART SM00448 193 303 1.7E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS05050 5162e01e9a355d78f0fdc910be489899 538 Pfam PF00072 Response regulator receiver domain 195 303 2.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS05050 5162e01e9a355d78f0fdc910be489899 538 SMART SM00862 338 414 3.9E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS05050 5162e01e9a355d78f0fdc910be489899 538 Gene3D G3DSA:1.10.10.10 311 420 7.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05050 5162e01e9a355d78f0fdc910be489899 538 SUPERFAMILY SSF52172 184 314 8.68E-37 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SUPERFAMILY SSF48452 93 262 4.11E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 PRINTS PR00364 Disease resistance protein signature 375 389 2.4E-9 T 28-03-2018 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 PRINTS PR00364 Disease resistance protein signature 460 474 2.4E-9 T 28-03-2018 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 PRINTS PR00364 Disease resistance protein signature 298 313 2.4E-9 T 28-03-2018 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 Gene3D G3DSA:3.40.50.300 259 415 1.2E-17 T 28-03-2018 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SUPERFAMILY SSF48452 744 869 1.66E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SMART SM01043 97 241 3.5E-47 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 Gene3D G3DSA:1.10.10.10 1 93 1.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 Pfam PF00931 NB-ARC domain 298 479 1.6E-13 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 Gene3D G3DSA:1.25.40.10 94 258 1.4E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 Gene3D G3DSA:1.25.40.10 758 954 2.0E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 Gene3D G3DSA:1.10.150.200 691 757 0.35 T 28-03-2018 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SMART SM00862 17 90 4.4E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SMART SM00028 832 865 0.12 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SMART SM00028 872 905 52.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SMART SM00028 912 945 91.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SMART SM00028 102 135 420.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SMART SM00028 752 785 27.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SMART SM00028 792 825 59.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 Pfam PF03704 Bacterial transcriptional activator domain 97 241 3.1E-41 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SUPERFAMILY SSF48452 831 945 2.12E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SUPERFAMILY SSF46894 5 90 2.69E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 SUPERFAMILY SSF52540 256 525 7.06E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00260 8873eca2837f796f5d25b466b4b47e40 976 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 90 6.7E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS30320 71dd9ae3ecb8a7c0921247160d5e275c 61 Gene3D G3DSA:2.30.170.40 2 61 7.7E-24 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30320 71dd9ae3ecb8a7c0921247160d5e275c 61 SUPERFAMILY SSF143800 2 59 7.26E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30320 71dd9ae3ecb8a7c0921247160d5e275c 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 56 1.7E-23 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30320 71dd9ae3ecb8a7c0921247160d5e275c 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 17.052 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30320 71dd9ae3ecb8a7c0921247160d5e275c 61 Pfam PF00830 Ribosomal L28 family 4 58 5.7E-25 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS18690 79f1254a5d80bd39a2385e488c837e60 226 SUPERFAMILY SSF109854 19 139 1.28E-14 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS18690 79f1254a5d80bd39a2385e488c837e60 226 Gene3D G3DSA:1.20.120.450 8 124 2.8E-14 T 28-03-2018 SMD44_RS18690 79f1254a5d80bd39a2385e488c837e60 226 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 113 1.3E-9 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS18690 79f1254a5d80bd39a2385e488c837e60 226 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 22 205 3.7E-27 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS38905 d379586400106b661c848a77714d26e5 662 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38905 d379586400106b661c848a77714d26e5 662 Gene3D G3DSA:3.40.50.980 170 323 2.5E-35 T 28-03-2018 SMD44_RS38905 d379586400106b661c848a77714d26e5 662 Gene3D G3DSA:3.40.50.980 11 169 4.2E-46 T 28-03-2018 SMD44_RS38905 d379586400106b661c848a77714d26e5 662 Gene3D G3DSA:3.30.300.30 407 568 2.2E-29 T 28-03-2018 SMD44_RS38905 d379586400106b661c848a77714d26e5 662 Pfam PF00501 AMP-binding enzyme 19 412 4.1E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38905 d379586400106b661c848a77714d26e5 662 SUPERFAMILY SSF56801 8 528 2.22E-141 T 28-03-2018 SMD44_RS38905 d379586400106b661c848a77714d26e5 662 Gene3D G3DSA:2.30.38.10 324 405 1.4E-22 T 28-03-2018 SMD44_RS38905 d379586400106b661c848a77714d26e5 662 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 518 3.7E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS38905 d379586400106b661c848a77714d26e5 662 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 40 436 1.8E-130 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 SUPERFAMILY SSF46785 5 88 3.12E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 Gene3D G3DSA:1.10.10.10 3 84 6.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 Gene3D G3DSA:3.40.190.10 177 273 9.6E-10 T 28-03-2018 SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.2E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 Pfam PF03466 LysR substrate binding domain 88 296 3.2E-30 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 SUPERFAMILY SSF53850 88 300 9.23E-26 T 28-03-2018 SMD44_RS24310 b95df3ba368eb552d86b9fadd02c8971 322 Gene3D G3DSA:3.40.190.10 89 176 3.2E-18 T 28-03-2018 SMD44_RS32280 b8ec020dc905a306409d28d280b1de8c 309 SUPERFAMILY SSF161098 51 296 9.42E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS32280 b8ec020dc905a306409d28d280b1de8c 309 Gene3D G3DSA:1.10.3720.10 57 306 2.1E-45 T 28-03-2018 SMD44_RS32280 b8ec020dc905a306409d28d280b1de8c 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 304 2.9E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS05785 53fe8de2da1cf3bbbb0dd9b5b1f98611 157 Pfam PF00877 NlpC/P60 family 56 142 1.3E-24 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS05785 53fe8de2da1cf3bbbb0dd9b5b1f98611 157 Gene3D G3DSA:3.90.1720.10 34 157 5.5E-33 T 28-03-2018 SMD44_RS05785 53fe8de2da1cf3bbbb0dd9b5b1f98611 157 SUPERFAMILY SSF54001 42 155 4.76E-35 T 28-03-2018 SMD44_RS25850 2a9b42f9d9426939cc94dd1212900bff 584 Gene3D G3DSA:3.40.1000.10 447 583 3.3E-24 T 28-03-2018 SMD44_RS25850 2a9b42f9d9426939cc94dd1212900bff 584 SMART SM00220 10 264 8.9E-58 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25850 2a9b42f9d9426939cc94dd1212900bff 584 SUPERFAMILY SSF56112 7 316 7.82E-68 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS25850 2a9b42f9d9426939cc94dd1212900bff 584 Gene3D G3DSA:3.30.200.20 5 97 9.1E-20 T 28-03-2018 SMD44_RS25850 2a9b42f9d9426939cc94dd1212900bff 584 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS25850 2a9b42f9d9426939cc94dd1212900bff 584 Pfam PF00069 Protein kinase domain 10 261 2.8E-46 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25850 2a9b42f9d9426939cc94dd1212900bff 584 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS25850 2a9b42f9d9426939cc94dd1212900bff 584 Gene3D G3DSA:1.10.510.10 98 326 3.0E-48 T 28-03-2018 SMD44_RS07685 35b53fa6e3f23430a222b34660b10444 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 213 5.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS07685 35b53fa6e3f23430a222b34660b10444 265 SUPERFAMILY SSF161098 8 202 2.35E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS07685 35b53fa6e3f23430a222b34660b10444 265 Gene3D G3DSA:1.10.3720.10 4 218 1.1E-34 T 28-03-2018 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 112 331 7.7E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 110 331 1.0E-93 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 PRINTS PR00046 Major sigma-70 factor signature 302 317 8.0E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 PRINTS PR00046 Major sigma-70 factor signature 317 328 8.0E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 PRINTS PR00046 Major sigma-70 factor signature 139 152 8.0E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 PRINTS PR00046 Major sigma-70 factor signature 285 297 8.0E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 Pfam PF04545 Sigma-70, region 4 282 330 1.4E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 139 152 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 Gene3D G3DSA:1.10.601.10 73 183 6.2E-26 T 28-03-2018 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 SUPERFAMILY SSF88946 81 184 3.61E-31 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 SUPERFAMILY SSF88659 251 332 4.11E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 Pfam PF04542 Sigma-70 region 2 115 184 6.5E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 SUPERFAMILY SSF88659 188 263 6.1E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 Pfam PF04539 Sigma-70 region 3 195 261 1.8E-15 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 Gene3D G3DSA:1.10.10.10 239 336 8.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16610 59c1375591f805f86ef12eabc4890aef 336 Gene3D G3DSA:1.10.10.10 185 237 5.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10840 0bbaadf763c947e778aa2f4abd6194ba 242 SUPERFAMILY SSF51366 4 237 3.22E-64 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD44_RS10840 0bbaadf763c947e778aa2f4abd6194ba 242 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 238 31.896 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 SMD44_RS10840 0bbaadf763c947e778aa2f4abd6194ba 242 Gene3D G3DSA:3.20.20.70 4 242 1.1E-53 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS10840 0bbaadf763c947e778aa2f4abd6194ba 242 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 4 239 1.3E-117 T 28-03-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 SMD44_RS10840 0bbaadf763c947e778aa2f4abd6194ba 242 Pfam PF00977 Histidine biosynthesis protein 6 231 1.5E-63 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 SUPERFAMILY SSF55048 576 640 3.14E-13 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Gene3D G3DSA:3.40.47.10 1 180 4.2E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Gene3D G3DSA:3.40.366.10 446 588 3.3E-51 T 28-03-2018 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Gene3D G3DSA:3.40.366.10 633 724 1.0E-20 T 28-03-2018 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 167 3.5E-61 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 SMART SM00825 Beta-ketoacyl synthase 1 345 5.0E-152 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 453 724 2.5E-109 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Gene3D G3DSA:3.30.70.250 589 632 1.4E-19 T 28-03-2018 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Pfam PF00698 Acyl transferase domain 453 718 1.4E-48 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 295 414 5.4E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 SUPERFAMILY SSF52151 450 577 4.45E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 SUPERFAMILY SSF52151 641 723 4.45E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Gene3D G3DSA:3.40.47.10 182 343 3.2E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 SUPERFAMILY SSF53901 2 290 2.1E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 175 292 4.4E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36875 601cad78c114c75341e2d80af8672a8d 724 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 80 96 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 SUPERFAMILY SSF50249 112 179 4.23E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 Pfam PF08529 NusA N-terminal domain 6 103 1.2E-17 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 Gene3D G3DSA:3.30.300.20 258 329 6.9E-16 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 335 25.827 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 Gene3D G3DSA:2.40.50.140 115 178 1.6E-13 T 28-03-2018 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 SUPERFAMILY SSF54814 261 324 1.83E-14 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 SMART SM00316 113 178 2.0E-4 T 28-03-2018 IPR022967 RNA-binding domain, S1 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 78 322 8.7E-97 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 Gene3D G3DSA:3.30.300.20 179 256 2.4E-33 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 Pfam PF13184 NusA-like KH domain 210 278 2.7E-25 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 Gene3D G3DSA:3.30.1480.10 1 102 4.8E-30 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 SUPERFAMILY SSF54814 180 258 2.62E-28 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD44_RS30855 ff5206cd013a618c098c6096a16e0ae7 335 SUPERFAMILY SSF69705 3 102 9.81E-28 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMD44_RS41605 46fe620bf1c9a43ce9a494f1ec6cfc1e 167 Gene3D G3DSA:3.40.190.10 11 143 5.3E-4 T 28-03-2018 SMD44_RS36570 cd291102247629bfb0f87d259bacdf4e 237 PIRSF PIRSF011491 17 237 8.9E-78 T 28-03-2018 IPR016584 Methyltransferase VrtF-like SMD44_RS36570 cd291102247629bfb0f87d259bacdf4e 237 Pfam PF08242 Methyltransferase domain 72 169 9.2E-10 T 28-03-2018 IPR013217 Methyltransferase type 12 SMD44_RS36570 cd291102247629bfb0f87d259bacdf4e 237 Gene3D G3DSA:3.40.50.150 5 237 2.1E-18 T 28-03-2018 SMD44_RS36570 cd291102247629bfb0f87d259bacdf4e 237 SUPERFAMILY SSF53335 67 191 4.56E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS06130 d279fa90dfe12e80bdbf0f1db79614ba 208 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 9.2E-16 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal SMD44_RS06130 d279fa90dfe12e80bdbf0f1db79614ba 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site SMD44_RS06130 d279fa90dfe12e80bdbf0f1db79614ba 208 SUPERFAMILY SSF54980 138 199 1.44E-14 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS06130 d279fa90dfe12e80bdbf0f1db79614ba 208 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 6.1E-29 T 28-03-2018 IPR001498 Impact, N-terminal SMD44_RS06130 d279fa90dfe12e80bdbf0f1db79614ba 208 SUPERFAMILY SSF54211 3 130 3.79E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS06130 d279fa90dfe12e80bdbf0f1db79614ba 208 Gene3D G3DSA:3.30.70.240 135 198 1.7E-21 T 28-03-2018 SMD44_RS06130 d279fa90dfe12e80bdbf0f1db79614ba 208 Gene3D G3DSA:3.30.230.30 4 132 1.2E-42 T 28-03-2018 IPR001498 Impact, N-terminal SMD44_RS06130 d279fa90dfe12e80bdbf0f1db79614ba 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 198 3.7E-56 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal SMD44_RS27695 d8a0cff54e799a71bfc4173ecb980daf 318 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 35 78 2.0E-8 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS27695 d8a0cff54e799a71bfc4173ecb980daf 318 Gene3D G3DSA:1.10.3720.10 40 307 3.5E-43 T 28-03-2018 SMD44_RS27695 d8a0cff54e799a71bfc4173ecb980daf 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 318 6.6E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS27695 d8a0cff54e799a71bfc4173ecb980daf 318 SUPERFAMILY SSF161098 113 303 2.22E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS10445 a48745722c0d90dc440a181505ade012 460 Pfam PF01546 Peptidase family M20/M25/M40 86 446 8.4E-21 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS10445 a48745722c0d90dc440a181505ade012 460 Pfam PF07687 Peptidase dimerisation domain 198 344 1.8E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS10445 a48745722c0d90dc440a181505ade012 460 Gene3D G3DSA:3.40.630.10 7 204 2.3E-26 T 28-03-2018 SMD44_RS10445 a48745722c0d90dc440a181505ade012 460 Gene3D G3DSA:3.30.70.360 205 359 3.0E-30 T 28-03-2018 SMD44_RS10445 a48745722c0d90dc440a181505ade012 460 SUPERFAMILY SSF53187 5 201 8.86E-46 T 28-03-2018 SMD44_RS10445 a48745722c0d90dc440a181505ade012 460 SUPERFAMILY SSF53187 362 449 8.86E-46 T 28-03-2018 SMD44_RS09730 eb447cc1c4e0d7f229683a234ad0b54f 245 SUPERFAMILY SSF52833 1 214 1.64E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS09730 eb447cc1c4e0d7f229683a234ad0b54f 245 Gene3D G3DSA:3.40.30.10 1 211 1.3E-52 T 28-03-2018 SMD44_RS09730 eb447cc1c4e0d7f229683a234ad0b54f 245 Pfam PF01323 DSBA-like thioredoxin domain 2 209 1.2E-40 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 SUPERFAMILY SSF56784 9 234 1.11E-43 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 207 1.5E-19 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 Gene3D G3DSA:3.40.50.1000 99 240 3.2E-31 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 Gene3D G3DSA:1.10.150.240 32 98 0.0043 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 116 202 1.0E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 167 2.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 2.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 44 57 2.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 120 133 2.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 197 210 2.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS30210 f6e0c0705e64ea8a22698e5e790979e4 247 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 92 207 2.8E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS03415 ad861996db1102c19343dda0c18bef66 193 Gene3D G3DSA:1.20.59.10 39 116 8.0E-18 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS03415 ad861996db1102c19343dda0c18bef66 193 SMART SM00830 39 111 2.3E-14 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS03415 ad861996db1102c19343dda0c18bef66 193 Pfam PF01817 Chorismate mutase type II 41 108 1.5E-9 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS03415 ad861996db1102c19343dda0c18bef66 193 SUPERFAMILY SSF48600 39 192 1.44E-34 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS03415 ad861996db1102c19343dda0c18bef66 193 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 36 147 1.1E-29 T 28-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS03415 ad861996db1102c19343dda0c18bef66 193 Gene3D G3DSA:1.20.59.10 117 150 0.023 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS28575 6fea38f8b63582ae6db659f2328cfade 311 Pfam PF00296 Luciferase-like monooxygenase 30 284 5.0E-13 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS28575 6fea38f8b63582ae6db659f2328cfade 311 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 18 309 4.5E-89 T 28-03-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted SMD44_RS28575 6fea38f8b63582ae6db659f2328cfade 311 SUPERFAMILY SSF51679 21 304 4.21E-37 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS28575 6fea38f8b63582ae6db659f2328cfade 311 Gene3D G3DSA:3.20.20.30 14 309 5.0E-29 T 28-03-2018 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 SUPERFAMILY SSF51905 1 305 3.46E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 7.1E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 7.1E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 7.1E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 7.1E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.9E-12 T 28-03-2018 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.9E-12 T 28-03-2018 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.9E-12 T 28-03-2018 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.9E-12 T 28-03-2018 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 Gene3D G3DSA:3.50.50.60 242 323 2.5E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 294 3.9E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 Gene3D G3DSA:3.50.50.60 107 240 8.5E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00545 a45b0ee15771c4af72431a2fc7edb4ed 399 Gene3D G3DSA:3.50.50.60 1 106 2.4E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS15200 f49d64adad86ea5489a73613d4a2e27a 248 SUPERFAMILY SSF161098 9 196 3.79E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15200 f49d64adad86ea5489a73613d4a2e27a 248 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 10 213 6.9E-73 T 28-03-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC SMD44_RS15200 f49d64adad86ea5489a73613d4a2e27a 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 211 9.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15200 f49d64adad86ea5489a73613d4a2e27a 248 Gene3D G3DSA:1.10.3720.10 3 213 3.7E-37 T 28-03-2018 SMD44_RS15200 f49d64adad86ea5489a73613d4a2e27a 248 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 105 1.2E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD44_RS13150 b94fd78ecedeaa9f76bc54bcf987cd81 219 Gene3D G3DSA:2.60.120.10 8 216 1.6E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS13150 b94fd78ecedeaa9f76bc54bcf987cd81 219 SUPERFAMILY SSF51182 10 138 2.31E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 SUPERFAMILY SSF48452 134 358 1.21E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 Gene3D G3DSA:1.25.40.10 244 317 5.8E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 Gene3D G3DSA:1.25.40.10 127 243 3.0E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 SUPERFAMILY SSF48452 404 511 1.39E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 SMART SM00028 288 321 0.0051 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 SMART SM00028 460 493 0.11 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 SMART SM00028 322 355 17.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 SMART SM00028 183 216 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 Gene3D G3DSA:1.25.20.10 396 509 1.4E-10 T 28-03-2018 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 Gene3D G3DSA:1.25.40.10 318 381 2.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 Pfam PF13432 Tetratricopeptide repeat 327 381 0.0014 T 28-03-2018 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 Pfam PF13432 Tetratricopeptide repeat 440 491 1.2E-4 T 28-03-2018 SMD44_RS15745 3782d3ae60b0d7757bae12a002e6ec59 541 Pfam PF13432 Tetratricopeptide repeat 261 321 3.3E-4 T 28-03-2018 SMD44_RS32415 a2f0a830458e74ab702859655b5a1ee4 556 Pfam PF08386 TAP-like protein 436 535 2.8E-27 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD44_RS32415 a2f0a830458e74ab702859655b5a1ee4 556 SUPERFAMILY SSF53474 364 523 2.36E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS32415 a2f0a830458e74ab702859655b5a1ee4 556 SUPERFAMILY SSF53474 225 279 2.36E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS32415 a2f0a830458e74ab702859655b5a1ee4 556 SUPERFAMILY SSF53474 128 180 2.36E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS32415 a2f0a830458e74ab702859655b5a1ee4 556 Gene3D G3DSA:3.40.50.1820 73 526 1.2E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Pfam PF01839 FG-GAP repeat 92 128 8.1E-11 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Pfam PF01839 FG-GAP repeat 392 430 7.8E-7 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Pfam PF01839 FG-GAP repeat 38 62 1.3E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Pfam PF01839 FG-GAP repeat 264 292 1.5E-6 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Pfam PF01839 FG-GAP repeat 323 359 5.2E-8 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 SUPERFAMILY SSF69318 37 416 5.17E-50 T 28-03-2018 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 SMART SM00191 264 306 54.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 SMART SM00191 319 380 6.1E-5 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 SMART SM00191 388 446 3.7E-7 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 SMART SM00191 88 144 2.4E-6 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 SMART SM00191 21 75 3.3 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Gene3D G3DSA:2.60.40.680 338 418 2.6E-15 T 28-03-2018 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Gene3D G3DSA:2.60.40.680 103 180 1.9E-13 T 28-03-2018 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Gene3D G3DSA:2.60.40.680 17 102 3.3E-17 T 28-03-2018 SMD44_RS22435 b9dd3ed11c153b3fffad0fd735f17296 464 Gene3D G3DSA:2.60.40.680 186 337 3.6E-17 T 28-03-2018 SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 Pfam PF07691 PA14 domain 62 199 5.7E-25 T 28-03-2018 IPR011658 PA14 domain SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 SUPERFAMILY SSF56988 120 227 1.57E-13 T 28-03-2018 SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 Gene3D G3DSA:2.60.120.560 829 1017 2.2E-33 T 28-03-2018 SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 Gene3D G3DSA:2.60.120.260 45 199 1.7E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 Gene3D G3DSA:2.120.10.30 236 482 2.3E-13 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 Gene3D G3DSA:2.120.10.30 483 572 1.4E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 SUPERFAMILY SSF49785 693 821 7.97E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 SUPERFAMILY SSF50952 251 549 9.81E-18 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 Pfam PF16990 Carbohydrate binding module (family 35) 695 823 1.5E-16 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 Gene3D G3DSA:2.60.120.260 694 828 2.2E-31 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 Pfam PF06439 Domain of Unknown Function (DUF1080) 828 1014 4.5E-34 T 28-03-2018 IPR010496 Domain of unknown function DUF1080 SMD44_RS40750 b12392328d61aca497cdbbfe6542b3bd 1017 SMART SM00758 61 202 3.8E-35 T 28-03-2018 IPR011658 PA14 domain SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 Pfam PF00149 Calcineurin-like phosphoesterase 59 320 4.4E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 Gene3D G3DSA:3.60.21.10 43 399 4.5E-73 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 SUPERFAMILY SSF56300 49 395 1.39E-64 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 Gene3D G3DSA:3.90.780.10 400 607 3.0E-48 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 PRINTS PR01607 Apyrase family signature 541 560 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 PRINTS PR01607 Apyrase family signature 303 326 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 PRINTS PR01607 Apyrase family signature 465 488 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 PRINTS PR01607 Apyrase family signature 52 70 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 SUPERFAMILY SSF55816 398 607 2.22E-46 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS19335 4891e5405f1c31eb5d3b509207af07e3 608 Pfam PF02872 5'-nucleotidase, C-terminal domain 401 564 3.8E-37 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS39195 fb71f7ab2e7d4795af1a1c30d0720bcb 327 Gene3D G3DSA:3.40.109.10 110 327 8.3E-28 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS39195 fb71f7ab2e7d4795af1a1c30d0720bcb 327 Gene3D G3DSA:3.40.109.30 1 77 6.7E-13 T 28-03-2018 SMD44_RS39195 fb71f7ab2e7d4795af1a1c30d0720bcb 327 SUPERFAMILY SSF55469 219 323 1.68E-5 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS39195 fb71f7ab2e7d4795af1a1c30d0720bcb 327 SUPERFAMILY SSF55469 113 156 1.68E-5 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS39195 fb71f7ab2e7d4795af1a1c30d0720bcb 327 SUPERFAMILY SSF55469 2 76 1.31E-9 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS27445 c2920c5b0665b9257bbf5699c8c1e425 184 Pfam PF00578 AhpC/TSA family 4 136 1.8E-33 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD44_RS27445 c2920c5b0665b9257bbf5699c8c1e425 184 PIRSF PIRSF000239 1 184 2.5E-50 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD44_RS27445 c2920c5b0665b9257bbf5699c8c1e425 184 SUPERFAMILY SSF52833 2 177 3.88E-54 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS27445 c2920c5b0665b9257bbf5699c8c1e425 184 Gene3D G3DSA:3.30.1020.10 153 183 5.5E-6 T 28-03-2018 SMD44_RS27445 c2920c5b0665b9257bbf5699c8c1e425 184 Gene3D G3DSA:3.40.30.10 1 152 1.6E-37 T 28-03-2018 SMD44_RS01690 b65bac7706107650fcb7624a79f2c709 322 Gene3D G3DSA:1.10.260.40 10 103 1.2E-6 T 28-03-2018 SMD44_RS01690 b65bac7706107650fcb7624a79f2c709 322 SUPERFAMILY SSF50370 176 320 1.81E-7 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS01690 b65bac7706107650fcb7624a79f2c709 322 Gene3D G3DSA:2.80.10.50 139 322 1.2E-10 T 28-03-2018 SMD44_RS18985 88b2fcfceb2ad8e3ad7c8e83758473d6 313 Pfam PF00588 SpoU rRNA Methylase family 165 306 3.0E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMD44_RS18985 88b2fcfceb2ad8e3ad7c8e83758473d6 313 SMART SM00967 71 148 2.2E-18 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SMD44_RS18985 88b2fcfceb2ad8e3ad7c8e83758473d6 313 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 71 148 5.0E-19 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SMD44_RS18985 88b2fcfceb2ad8e3ad7c8e83758473d6 313 Gene3D G3DSA:3.40.1280.10 145 313 9.0E-43 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD44_RS18985 88b2fcfceb2ad8e3ad7c8e83758473d6 313 SUPERFAMILY SSF55315 66 145 9.77E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SMD44_RS18985 88b2fcfceb2ad8e3ad7c8e83758473d6 313 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 69 312 5.9E-59 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 SMD44_RS18985 88b2fcfceb2ad8e3ad7c8e83758473d6 313 Gene3D G3DSA:3.30.1330.30 58 144 2.7E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SMD44_RS18985 88b2fcfceb2ad8e3ad7c8e83758473d6 313 SUPERFAMILY SSF75217 136 312 5.56E-42 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SMD44_RS00230 3453c166d6a9b3a48cc0c92553567aeb 379 SUPERFAMILY SSF51717 47 218 3.61E-9 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS00230 3453c166d6a9b3a48cc0c92553567aeb 379 Pfam PF04551 GcpE protein 21 361 4.3E-127 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS00230 3453c166d6a9b3a48cc0c92553567aeb 379 PIRSF PIRSF004640 11 372 6.1E-138 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS00230 3453c166d6a9b3a48cc0c92553567aeb 379 SUPERFAMILY SSF56014 276 358 1.74E-13 T 28-03-2018 SMD44_RS00230 3453c166d6a9b3a48cc0c92553567aeb 379 Gene3D G3DSA:3.20.20.120 25 179 1.5E-18 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS00230 3453c166d6a9b3a48cc0c92553567aeb 379 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 2.9E-124 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS00230 3453c166d6a9b3a48cc0c92553567aeb 379 Gene3D G3DSA:3.30.413.10 275 375 0.003 T 28-03-2018 SMD44_RS00230 3453c166d6a9b3a48cc0c92553567aeb 379 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.647 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 4.9E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 4.9E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 4.9E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 4.9E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 4.9E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 4.9E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 4.9E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 Gene3D G3DSA:3.90.1820.10 1 286 2.7E-71 T 28-03-2018 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 Gene3D G3DSA:3.90.1820.10 287 431 5.1E-33 T 28-03-2018 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 SUPERFAMILY SSF51735 4 167 3.2E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 Pfam PF02056 Family 4 glycosyl hydrolase 5 186 7.2E-56 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 SUPERFAMILY SSF56327 170 426 6.69E-65 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD44_RS02045 146ebab8eb1a9d509a26e1a134c1ba6c 432 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 402 2.7E-59 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 167 181 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 SUPERFAMILY SSF55931 21 323 7.85E-110 T 28-03-2018 SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 SUPERFAMILY SSF89095 368 501 6.28E-25 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 Pfam PF02934 GatB/GatE catalytic domain 22 316 8.4E-103 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 SMART SM00845 354 501 4.9E-55 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 18 501 2.0E-142 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 Gene3D G3DSA:1.10.10.410 441 502 5.0E-16 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 Pfam PF02637 GatB domain 359 501 6.7E-41 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 SMD44_RS29840 98627f68033c4326080b34b60e97f9ce 505 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 18 502 35.848 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SMD44_RS17570 08033a88eb940518e64aab95c146b00f 278 SUPERFAMILY SSF47413 7 60 2.04E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS17570 08033a88eb940518e64aab95c146b00f 278 Gene3D G3DSA:1.10.260.40 2 67 1.3E-11 T 28-03-2018 SMD44_RS17570 08033a88eb940518e64aab95c146b00f 278 SMART SM00530 15 67 2.7E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS17570 08033a88eb940518e64aab95c146b00f 278 Pfam PF13560 Helix-turn-helix domain 11 62 3.6E-8 T 28-03-2018 SMD44_RS18820 7e34459b25d9b912f865a77eb7e35c92 282 Gene3D G3DSA:3.40.50.1000 29 281 1.6E-20 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18820 7e34459b25d9b912f865a77eb7e35c92 282 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 29 278 2.7E-29 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 SMD44_RS18820 7e34459b25d9b912f865a77eb7e35c92 282 SUPERFAMILY SSF56784 31 278 7.74E-33 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18820 7e34459b25d9b912f865a77eb7e35c92 282 Pfam PF02358 Trehalose-phosphatase 34 236 7.4E-25 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 SMD44_RS35685 15f7f0083d497bcb6346eeae333152bc 331 Gene3D G3DSA:1.10.10.10 34 331 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 Gene3D G3DSA:3.40.50.720 1 257 5.7E-61 T 28-03-2018 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 4.8E-51 T 28-03-2018 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 169 192 6.5E-44 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 13 30 6.5E-44 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 104 124 6.5E-44 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 207 226 6.5E-44 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 84 101 6.5E-44 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 233 252 6.5E-44 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 SUPERFAMILY SSF51735 6 253 3.58E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 7.4E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 7.4E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01260 2f6aabc264db78208a0ebb0b499a4c47 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 7.4E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS26570 cca7b9e6907ab94f711e768879f5ee5a 253 Gene3D G3DSA:3.10.20.30 11 123 2.0E-35 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS26570 cca7b9e6907ab94f711e768879f5ee5a 253 Pfam PF13183 4Fe-4S dicluster domain 163 235 6.2E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS26570 cca7b9e6907ab94f711e768879f5ee5a 253 SUPERFAMILY SSF46548 124 249 1.92E-33 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD44_RS26570 cca7b9e6907ab94f711e768879f5ee5a 253 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 26 245 9.0E-79 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26570 cca7b9e6907ab94f711e768879f5ee5a 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 165 176 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS26570 cca7b9e6907ab94f711e768879f5ee5a 253 SUPERFAMILY SSF54292 20 123 3.13E-29 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS26570 cca7b9e6907ab94f711e768879f5ee5a 253 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 23 128 8.6E-35 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26570 cca7b9e6907ab94f711e768879f5ee5a 253 Gene3D G3DSA:1.10.1060.10 124 252 3.1E-28 T 28-03-2018 SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 Gene3D G3DSA:1.10.10.10 185 229 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 SUPERFAMILY SSF55781 22 170 5.45E-22 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 SMART SM01012 172 227 3.3E-21 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 SUPERFAMILY SSF52172 155 227 4.87E-10 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 PIRSF PIRSF036625 1 238 5.8E-83 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 Pfam PF03861 ANTAR domain 174 227 5.2E-18 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 Gene3D G3DSA:3.30.450.40 2 184 2.2E-27 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 SMART SM00065 22 170 7.3E-4 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS33770 3d04541e7e1363876ab6be0e90a38b79 238 Pfam PF13185 GAF domain 23 158 8.2E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS11725 5bfc167ab15014efe781b5875f7a3c1b 135 SUPERFAMILY SSF54593 8 126 3.44E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS11725 5bfc167ab15014efe781b5875f7a3c1b 135 Gene3D G3DSA:3.10.180.10 5 135 1.7E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS11725 5bfc167ab15014efe781b5875f7a3c1b 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 123 8.5E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 Gene3D G3DSA:1.20.1250.20 19 210 2.9E-35 T 28-03-2018 SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 SUPERFAMILY SSF103473 15 212 4.19E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 SUPERFAMILY SSF103473 261 432 4.19E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 SUPERFAMILY SSF103473 484 509 4.19E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 1.9E-8 T 28-03-2018 SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 1.9E-8 T 28-03-2018 SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 1.9E-8 T 28-03-2018 SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 88 110 1.9E-8 T 28-03-2018 SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 Gene3D G3DSA:1.20.1250.20 272 511 4.4E-21 T 28-03-2018 SMD44_RS08955 f33ae99f771199a69bb8cdb1c797c5ba 539 Pfam PF07690 Major Facilitator Superfamily 30 422 8.8E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS37155 f3cef6179ea71fdbafb536a137953fef 799 SUPERFAMILY SSF52540 499 770 4.71E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37155 f3cef6179ea71fdbafb536a137953fef 799 Gene3D G3DSA:3.40.50.300 20 122 2.7E-4 T 28-03-2018 SMD44_RS37155 f3cef6179ea71fdbafb536a137953fef 799 Gene3D G3DSA:1.20.1580.10 123 376 2.0E-54 T 28-03-2018 SMD44_RS37155 f3cef6179ea71fdbafb536a137953fef 799 SUPERFAMILY SSF52540 318 458 1.61E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37155 f3cef6179ea71fdbafb536a137953fef 799 SUPERFAMILY SSF52540 21 69 1.61E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37155 f3cef6179ea71fdbafb536a137953fef 799 Pfam PF00005 ABC transporter 507 718 3.3E-10 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS37155 f3cef6179ea71fdbafb536a137953fef 799 Gene3D G3DSA:3.40.50.300 492 797 4.4E-54 T 28-03-2018 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 SUPERFAMILY SSF55021 2 71 4.58E-8 T 28-03-2018 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 157 374 6.1E-78 T 28-03-2018 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 Pfam PF13740 ACT domain 1 71 2.8E-14 T 28-03-2018 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 Gene3D G3DSA:3.30.70.260 1 77 8.4E-12 T 28-03-2018 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 Gene3D G3DSA:3.30.70.260 86 167 7.8E-13 T 28-03-2018 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 Gene3D G3DSA:3.40.50.1000 229 374 1.2E-27 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 171 341 1.1E-28 T 28-03-2018 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 Pfam PF12710 haloacid dehalogenase-like hydrolase 172 339 5.7E-23 T 28-03-2018 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 Gene3D G3DSA:1.10.150.210 182 228 4.4E-22 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 SMD44_RS09330 6c763f69f098f8cd72ed6bf38add3e06 391 SUPERFAMILY SSF56784 170 377 3.07E-48 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS20075 527c7f51f4a75befc2ec469834743e7d 135 PRINTS PR00502 NUDIX hydrolase family signature 25 39 2.5E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS20075 527c7f51f4a75befc2ec469834743e7d 135 PRINTS PR00502 NUDIX hydrolase family signature 39 54 2.5E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS20075 527c7f51f4a75befc2ec469834743e7d 135 SUPERFAMILY SSF55811 1 119 2.71E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS20075 527c7f51f4a75befc2ec469834743e7d 135 ProSitePatterns PS00893 Nudix box signature. 30 51 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS20075 527c7f51f4a75befc2ec469834743e7d 135 Gene3D G3DSA:3.90.79.10 1 129 8.0E-25 T 28-03-2018 SMD44_RS20075 527c7f51f4a75befc2ec469834743e7d 135 Pfam PF00293 NUDIX domain 2 108 1.1E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS15055 a9967b0fda8a39d13ce48173f6f060be 342 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 336 5.2E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15055 a9967b0fda8a39d13ce48173f6f060be 342 SUPERFAMILY SSF161098 97 328 6.8E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15055 a9967b0fda8a39d13ce48173f6f060be 342 Gene3D G3DSA:1.10.3720.10 53 342 2.8E-52 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 484 5.8E-186 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 SMD44_RS10315 b187236573ef642e95578692d2246795 496 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 40 130 4.3E-21 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 SMD44_RS10315 b187236573ef642e95578692d2246795 496 Gene3D G3DSA:3.40.50.720 145 240 1.7E-20 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 Gene3D G3DSA:1.10.1060.10 5 144 3.8E-37 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 391 466 1.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10315 b187236573ef642e95578692d2246795 496 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 314 2.7E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10315 b187236573ef642e95578692d2246795 496 Gene3D G3DSA:3.50.50.60 241 328 1.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10315 b187236573ef642e95578692d2246795 496 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 8.8E-24 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 8.8E-24 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 8.8E-24 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 8.8E-24 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 SUPERFAMILY SSF51971 394 479 1.15E-9 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 SUPERFAMILY SSF51971 143 409 6.47E-56 T 28-03-2018 SMD44_RS10315 b187236573ef642e95578692d2246795 496 Gene3D G3DSA:3.50.50.60 414 490 1.4E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS10315 b187236573ef642e95578692d2246795 496 SUPERFAMILY SSF46548 5 155 1.2E-35 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 SUPERFAMILY SSF49503 134 157 2.48E-40 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 SUPERFAMILY SSF49503 203 299 2.48E-40 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 Gene3D G3DSA:2.60.40.420 126 320 1.1E-45 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 SUPERFAMILY SSF81464 26 124 1.24E-18 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 210 280 1.1E-17 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 52 290 5.7E-47 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 263 280 3.3E-14 T 28-03-2018 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 111 3.3E-14 T 28-03-2018 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 245 262 3.3E-14 T 28-03-2018 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 245 3.3E-14 T 28-03-2018 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 134 153 3.3E-14 T 28-03-2018 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 Gene3D G3DSA:1.10.287.90 41 125 1.5E-17 T 28-03-2018 SMD44_RS11410 6760f57078d88038bd5c5f0895679098 320 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 226 274 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS25595 ddbf5184dabe84125157735ba88e19aa 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.0 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25595 ddbf5184dabe84125157735ba88e19aa 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site SMD44_RS25595 ddbf5184dabe84125157735ba88e19aa 60 SUPERFAMILY SSF55129 1 60 8.76E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMD44_RS25595 ddbf5184dabe84125157735ba88e19aa 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.5E-16 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMD44_RS25595 ddbf5184dabe84125157735ba88e19aa 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 3.7E-27 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25595 ddbf5184dabe84125157735ba88e19aa 60 PIRSF PIRSF002211 1 60 4.2E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25595 ddbf5184dabe84125157735ba88e19aa 60 Gene3D G3DSA:3.30.1390.20 4 58 1.8E-22 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMD44_RS38010 6e4bf4422d2de0cd6e527136dda8ee7a 225 SMART SM00953 41 186 9.6E-8 T 28-03-2018 IPR014914 RES domain SMD44_RS38010 6e4bf4422d2de0cd6e527136dda8ee7a 225 Pfam PF08808 RES domain 25 183 1.3E-21 T 28-03-2018 IPR014914 RES domain SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 Pfam PF12419 SNF2 Helicase protein 308 447 5.1E-42 T 28-03-2018 IPR022138 Helicase SWF/SNF-related SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 Gene3D G3DSA:3.40.50.10810 493 702 1.2E-48 T 28-03-2018 SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 SUPERFAMILY SSF52540 464 701 2.45E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 SMART SM00490 815 897 1.7E-25 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 Pfam PF00271 Helicase conserved C-terminal domain 786 897 1.5E-18 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 SMART SM00487 488 673 2.6E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 Gene3D G3DSA:3.40.50.300 773 935 5.3E-40 T 28-03-2018 SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 SUPERFAMILY SSF52540 708 953 2.42E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS39310 a94b47c2e1494ab1dff33d9f9ae21b25 959 Pfam PF00176 SNF2 family N-terminal domain 511 769 4.4E-51 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 SMD44_RS22085 41eae853f1240acbcc62091cc30d5e95 308 SUPERFAMILY SSF47413 11 65 1.01E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS22085 41eae853f1240acbcc62091cc30d5e95 308 Gene3D G3DSA:1.10.260.40 9 108 1.1E-11 T 28-03-2018 SMD44_RS22085 41eae853f1240acbcc62091cc30d5e95 308 SMART SM00530 15 70 1.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS22085 41eae853f1240acbcc62091cc30d5e95 308 Pfam PF13560 Helix-turn-helix domain 12 71 1.0E-11 T 28-03-2018 SMD44_RS16770 4e243ad179d5945d46ef831b12784624 465 SUPERFAMILY SSF51905 168 350 2.41E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16770 4e243ad179d5945d46ef831b12784624 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.3E-7 T 28-03-2018 SMD44_RS16770 4e243ad179d5945d46ef831b12784624 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 3.3E-7 T 28-03-2018 SMD44_RS16770 4e243ad179d5945d46ef831b12784624 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 3.3E-7 T 28-03-2018 SMD44_RS16770 4e243ad179d5945d46ef831b12784624 465 SUPERFAMILY SSF51905 7 192 5.13E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16770 4e243ad179d5945d46ef831b12784624 465 Gene3D G3DSA:3.50.50.60 130 347 1.3E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16770 4e243ad179d5945d46ef831b12784624 465 Gene3D G3DSA:3.50.50.60 2 129 5.5E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16770 4e243ad179d5945d46ef831b12784624 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 337 2.1E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08855 1bbad42017ae021a9babc12c30645619 381 Pfam PF13175 AAA ATPase domain 1 48 2.1E-10 T 28-03-2018 SMD44_RS08855 1bbad42017ae021a9babc12c30645619 381 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 201 332 1.3E-18 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS08855 1bbad42017ae021a9babc12c30645619 381 SUPERFAMILY SSF52540 168 199 6.35E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08855 1bbad42017ae021a9babc12c30645619 381 SUPERFAMILY SSF52540 245 340 6.35E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08855 1bbad42017ae021a9babc12c30645619 381 SUPERFAMILY SSF52540 1 127 6.35E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08855 1bbad42017ae021a9babc12c30645619 381 Gene3D G3DSA:3.40.50.300 1 227 4.4E-10 T 28-03-2018 SMD44_RS08855 1bbad42017ae021a9babc12c30645619 381 Gene3D G3DSA:3.40.50.300 228 365 8.5E-14 T 28-03-2018 SMD44_RS08855 1bbad42017ae021a9babc12c30645619 381 PIRSF PIRSF029347 1 381 3.1E-136 T 28-03-2018 IPR014555 RecF-like SMD44_RS01165 2bcc986240eaac068fdc4254f0e7563b 408 SUPERFAMILY SSF53756 2 406 2.37E-78 T 28-03-2018 SMD44_RS01165 2bcc986240eaac068fdc4254f0e7563b 408 Gene3D G3DSA:3.40.50.2000 1 249 4.2E-36 T 28-03-2018 SMD44_RS01165 2bcc986240eaac068fdc4254f0e7563b 408 Gene3D G3DSA:3.40.50.2000 250 394 2.9E-29 T 28-03-2018 SMD44_RS01165 2bcc986240eaac068fdc4254f0e7563b 408 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 2 93 2.7E-9 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 136 220 8.0E-21 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 SUPERFAMILY SSF46946 135 218 3.4E-24 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 Pfam PF06827 Zinc finger found in FPG and IleRS 243 270 2.6E-8 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 Gene3D G3DSA:3.20.190.10 1 131 2.1E-24 T 28-03-2018 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 SMART SM01232 136 228 1.6E-30 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 SMART SM00898 2 122 1.5E-24 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 SUPERFAMILY SSF57716 232 271 2.11E-11 T 28-03-2018 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 Gene3D G3DSA:1.10.8.50 132 271 2.1E-40 T 28-03-2018 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 85 2.1E-14 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS37265 9acee9d6b4640bc33cdab3bf00aad9b4 286 SUPERFAMILY SSF81624 2 141 1.96E-24 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS09930 c10e90f08974e3034323d8189076a77b 232 Gene3D G3DSA:3.30.70.100 122 232 1.7E-13 T 28-03-2018 SMD44_RS09930 c10e90f08974e3034323d8189076a77b 232 Gene3D G3DSA:3.30.70.100 10 119 8.5E-17 T 28-03-2018 SMD44_RS09930 c10e90f08974e3034323d8189076a77b 232 SUPERFAMILY SSF54909 127 211 4.47E-9 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS09930 c10e90f08974e3034323d8189076a77b 232 Pfam PF03992 Antibiotic biosynthesis monooxygenase 29 85 3.6E-5 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD44_RS09930 c10e90f08974e3034323d8189076a77b 232 Pfam PF03992 Antibiotic biosynthesis monooxygenase 128 194 2.1E-11 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD44_RS09930 c10e90f08974e3034323d8189076a77b 232 SUPERFAMILY SSF54909 23 86 1.48E-8 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 SMART SM00838 416 500 5.4E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 SUPERFAMILY SSF50447 184 304 1.63E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Pfam PF00009 Elongation factor Tu GTP binding domain 19 200 1.0E-51 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Pfam PF06421 GTP-binding protein LepA C-terminus 507 612 4.5E-48 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 SUPERFAMILY SSF52540 13 220 2.65E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 195 1.4E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Gene3D G3DSA:3.30.70.870 307 386 2.7E-27 T 28-03-2018 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Gene3D G3DSA:3.30.70.240 411 567 3.2E-28 T 28-03-2018 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 PRINTS PR00315 GTP-binding elongation factor signature 93 103 5.6E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 PRINTS PR00315 GTP-binding elongation factor signature 109 120 5.6E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 PRINTS PR00315 GTP-binding elongation factor signature 145 154 5.6E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 PRINTS PR00315 GTP-binding elongation factor signature 64 72 5.6E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 PRINTS PR00315 GTP-binding elongation factor signature 21 34 5.6E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 SUPERFAMILY SSF54980 310 389 1.51E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 TIGRFAM TIGR01393 lepA: elongation factor 4 19 614 8.4E-291 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Pfam PF03144 Elongation factor Tu domain 2 224 294 1.5E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Pfam PF00679 Elongation factor G C-terminus 417 503 1.2E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Hamap MF_00071 Elongation factor 4 [lepA]. 1 616 283.4 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 SUPERFAMILY SSF54980 417 512 1.06E-23 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Gene3D G3DSA:2.40.30.10 207 306 1.2E-20 T 28-03-2018 SMD44_RS13840 c3459d4084d4d9d67b3ac51d21da1fd2 621 Gene3D G3DSA:3.40.50.300 17 204 7.4E-35 T 28-03-2018 SMD44_RS15105 4ea6f7187e2bcc5dbb662558db496633 198 Gene3D G3DSA:3.40.50.1240 1 198 1.0E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS15105 4ea6f7187e2bcc5dbb662558db496633 198 SMART SM00855 4 153 2.9E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS15105 4ea6f7187e2bcc5dbb662558db496633 198 SUPERFAMILY SSF53254 1 196 4.12E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS15105 4ea6f7187e2bcc5dbb662558db496633 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 193 5.5E-49 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS15105 4ea6f7187e2bcc5dbb662558db496633 198 PIRSF PIRSF000709 1 171 3.0E-10 T 28-03-2018 SMD44_RS27555 c1e6595e38de98ad996221b035fa9d40 250 Pfam PF00480 ROK family 4 160 5.8E-16 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS27555 c1e6595e38de98ad996221b035fa9d40 250 SUPERFAMILY SSF53067 1 246 2.81E-37 T 28-03-2018 SMD44_RS27555 c1e6595e38de98ad996221b035fa9d40 250 Gene3D G3DSA:3.30.420.40 117 250 2.8E-29 T 28-03-2018 SMD44_RS27555 c1e6595e38de98ad996221b035fa9d40 250 Gene3D G3DSA:3.30.420.40 1 116 2.5E-21 T 28-03-2018 SMD44_RS34255 e7aaf557e7f7c62e684f0b2648223e58 244 SUPERFAMILY SSF53335 7 158 3.73E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS34255 e7aaf557e7f7c62e684f0b2648223e58 244 Gene3D G3DSA:3.40.50.150 3 224 1.0E-16 T 28-03-2018 SMD44_RS34255 e7aaf557e7f7c62e684f0b2648223e58 244 Pfam PF13649 Methyltransferase domain 54 148 6.9E-10 T 28-03-2018 SMD44_RS31285 e1a7fb18b750fd6aafb77abaa5f96a33 330 SUPERFAMILY SSF53850 38 326 1.37E-54 T 28-03-2018 SMD44_RS31285 e1a7fb18b750fd6aafb77abaa5f96a33 330 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 9 328 1.2E-81 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family SMD44_RS31285 e1a7fb18b750fd6aafb77abaa5f96a33 330 Pfam PF16868 NMT1-like family 45 326 5.2E-46 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family SMD44_RS31285 e1a7fb18b750fd6aafb77abaa5f96a33 330 Gene3D G3DSA:3.40.190.10 176 328 1.7E-33 T 28-03-2018 SMD44_RS31285 e1a7fb18b750fd6aafb77abaa5f96a33 330 Gene3D G3DSA:3.40.190.10 37 157 3.9E-11 T 28-03-2018 SMD44_RS41465 8f7c9f8e37b9776eb1fb51d8443d5549 795 SUPERFAMILY SSF56112 251 423 1.02E-8 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS41465 8f7c9f8e37b9776eb1fb51d8443d5549 795 Gene3D G3DSA:3.30.2430.10 33 169 7.4E-9 T 28-03-2018 SMD44_RS41465 8f7c9f8e37b9776eb1fb51d8443d5549 795 Gene3D G3DSA:1.10.510.10 247 515 2.4E-10 T 28-03-2018 SMD44_RS41465 8f7c9f8e37b9776eb1fb51d8443d5549 795 SUPERFAMILY SSF158745 538 720 1.57E-14 T 28-03-2018 SMD44_RS41465 8f7c9f8e37b9776eb1fb51d8443d5549 795 Gene3D G3DSA:1.50.10.20 516 741 2.7E-6 T 28-03-2018 SMD44_RS08760 2a32ea95f0292f524fdca7960af43633 349 SUPERFAMILY SSF53335 18 207 1.05E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS08760 2a32ea95f0292f524fdca7960af43633 349 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 221 328 1.3E-12 T 28-03-2018 SMD44_RS08760 2a32ea95f0292f524fdca7960af43633 349 Gene3D G3DSA:3.40.50.150 14 208 2.0E-36 T 28-03-2018 SMD44_RS08760 2a32ea95f0292f524fdca7960af43633 349 Gene3D G3DSA:3.10.180.10 209 348 5.2E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS08760 2a32ea95f0292f524fdca7960af43633 349 Pfam PF08241 Methyltransferase domain 58 151 1.1E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS08760 2a32ea95f0292f524fdca7960af43633 349 SUPERFAMILY SSF54593 218 346 5.38E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 5.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 5.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 5.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 SUPERFAMILY SSF51735 3 230 2.09E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 5.5E-52 T 28-03-2018 SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 4.2E-6 T 28-03-2018 SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 Gene3D G3DSA:3.40.50.720 1 39 1.2E-5 T 28-03-2018 SMD44_RS19830 a34dc095e29c82e972c509ee012252f2 234 Gene3D G3DSA:3.40.50.720 40 234 1.8E-63 T 28-03-2018 SMD44_RS39600 0ca0e9c25636bc2513a3bc1086c2d3c8 526 Gene3D G3DSA:1.50.10.10 242 489 7.0E-8 T 28-03-2018 SMD44_RS39600 0ca0e9c25636bc2513a3bc1086c2d3c8 526 SUPERFAMILY SSF158745 190 489 2.62E-19 T 28-03-2018 SMD44_RS39600 0ca0e9c25636bc2513a3bc1086c2d3c8 526 SMART SM01260 158 493 2.8E-5 T 28-03-2018 IPR007822 Lanthionine synthetase C-like SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 198 354 1.0E-13 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 SUPERFAMILY SSF54197 183 357 1.14E-29 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 103 356 4.8E-38 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 SUPERFAMILY SSF54197 37 179 9.45E-48 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 103 178 5.7E-26 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 Gene3D G3DSA:3.30.428.10 75 168 2.3E-35 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 Gene3D G3DSA:3.30.428.10 38 74 3.3E-4 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 Gene3D G3DSA:3.30.428.10 169 358 1.1E-25 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 154 171 - T 28-03-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMD44_RS17015 adb514de02bce3759a03f01de58fcfe3 358 PIRSF PIRSF000808 34 358 2.9E-107 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMD44_RS22350 fc1e4c82dc75231261375fffe3450a5b 566 Pfam PF00891 O-methyltransferase 321 541 3.2E-42 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD44_RS22350 fc1e4c82dc75231261375fffe3450a5b 566 Gene3D G3DSA:1.10.10.10 220 309 5.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22350 fc1e4c82dc75231261375fffe3450a5b 566 SUPERFAMILY SSF53335 317 549 6.91E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS22350 fc1e4c82dc75231261375fffe3450a5b 566 Gene3D G3DSA:3.40.50.150 310 559 2.2E-44 T 28-03-2018 SMD44_RS22350 fc1e4c82dc75231261375fffe3450a5b 566 SUPERFAMILY SSF46785 225 311 1.01E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15255 a7fbf6c25822232a448c479976d7b1ff 277 Gene3D G3DSA:3.20.20.70 49 261 3.9E-33 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS15255 a7fbf6c25822232a448c479976d7b1ff 277 SUPERFAMILY SSF51445 53 248 4.21E-20 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS15255 a7fbf6c25822232a448c479976d7b1ff 277 Pfam PF03537 Glycoside-hydrolase family GH114 49 264 1.6E-49 T 28-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain SMD44_RS17860 4ebd565c839ac8c0b41f4446c0ea6111 577 Gene3D G3DSA:2.30.40.10 1 69 4.8E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS17860 4ebd565c839ac8c0b41f4446c0ea6111 577 SUPERFAMILY SSF51338 1 55 1.64E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS17860 4ebd565c839ac8c0b41f4446c0ea6111 577 SUPERFAMILY SSF51338 497 560 1.64E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS17860 4ebd565c839ac8c0b41f4446c0ea6111 577 Pfam PF07969 Amidohydrolase family 48 550 1.1E-71 T 28-03-2018 IPR013108 Amidohydrolase 3 SMD44_RS17860 4ebd565c839ac8c0b41f4446c0ea6111 577 Gene3D G3DSA:2.30.40.10 480 556 9.2E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS17860 4ebd565c839ac8c0b41f4446c0ea6111 577 SUPERFAMILY SSF51556 363 497 2.89E-54 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS17860 4ebd565c839ac8c0b41f4446c0ea6111 577 SUPERFAMILY SSF51556 56 313 2.89E-54 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS17860 4ebd565c839ac8c0b41f4446c0ea6111 577 Gene3D G3DSA:3.20.20.140 70 479 5.7E-57 T 28-03-2018 SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 Gene3D G3DSA:3.40.630.30 1 127 3.4E-14 T 28-03-2018 SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 Pfam PF13527 Acetyltransferase (GNAT) domain 1 124 7.7E-31 T 28-03-2018 SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 Pfam PF13530 Sterol carrier protein domain 254 452 4.6E-39 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 Gene3D G3DSA:3.40.630.30 128 338 4.3E-48 T 28-03-2018 SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 SUPERFAMILY SSF55729 255 337 6.07E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 Gene3D G3DSA:3.30.1050.10 339 451 1.2E-30 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 SUPERFAMILY SSF55718 338 460 3.65E-17 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 SUPERFAMILY SSF55729 1 188 2.37E-42 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS18925 040f757337ed0843e48eae0560af9bbc 460 Hamap MF_01812 UPF0256 protein . 6 460 30.027 T 28-03-2018 IPR022902 N-acetyltransferase Eis SMD44_RS18595 f3457fe766a5080aecbc2fb49e4ddeb4 127 Gene3D G3DSA:2.40.50.140 2 74 4.0E-22 T 28-03-2018 SMD44_RS18595 f3457fe766a5080aecbc2fb49e4ddeb4 127 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site SMD44_RS18595 f3457fe766a5080aecbc2fb49e4ddeb4 127 SUPERFAMILY SSF50249 2 68 2.94E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS18595 f3457fe766a5080aecbc2fb49e4ddeb4 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 1.4E-21 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS18595 f3457fe766a5080aecbc2fb49e4ddeb4 127 SMART SM00357 3 65 4.7E-22 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SMD44_RS18595 f3457fe766a5080aecbc2fb49e4ddeb4 127 PRINTS PR00050 Cold shock protein signature 24 33 4.0E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS18595 f3457fe766a5080aecbc2fb49e4ddeb4 127 PRINTS PR00050 Cold shock protein signature 38 56 4.0E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS18595 f3457fe766a5080aecbc2fb49e4ddeb4 127 PRINTS PR00050 Cold shock protein signature 4 19 4.0E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS42705 069ba90f2954d37d0500668c31d1a969 276 SUPERFAMILY SSF53335 27 214 2.01E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS42705 069ba90f2954d37d0500668c31d1a969 276 Pfam PF13649 Methyltransferase domain 47 141 1.4E-13 T 28-03-2018 SMD44_RS42705 069ba90f2954d37d0500668c31d1a969 276 Gene3D G3DSA:3.40.50.150 10 275 4.7E-27 T 28-03-2018 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 SUPERFAMILY SSF55681 422 583 8.76E-92 T 28-03-2018 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 SUPERFAMILY SSF55681 118 298 8.76E-92 T 28-03-2018 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 555 4.0E-92 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 582 30.116 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 SUPERFAMILY SSF50249 4 107 1.64E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 Gene3D G3DSA:3.30.930.10 135 584 2.1E-90 T 28-03-2018 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 2.2E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 Pfam PF02938 GAD domain 316 403 1.1E-20 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 1.2E-20 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 1.2E-20 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 1.2E-20 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 1.2E-20 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 SUPERFAMILY SSF55261 297 414 2.45E-34 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 582 1.9E-183 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 SMD44_RS21895 dda8687a379e79c3cae3400c9f094dab 602 Gene3D G3DSA:2.40.50.140 1 110 3.7E-24 T 28-03-2018 SMD44_RS06280 161c4f5494eae223d842adf771c94513 540 SUPERFAMILY SSF53474 218 360 6.35E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06280 161c4f5494eae223d842adf771c94513 540 SUPERFAMILY SSF53474 127 177 6.35E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06280 161c4f5494eae223d842adf771c94513 540 Gene3D G3DSA:3.40.50.1820 101 367 4.1E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06280 161c4f5494eae223d842adf771c94513 540 Gene3D G3DSA:3.40.50.1820 371 527 2.2E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06280 161c4f5494eae223d842adf771c94513 540 SUPERFAMILY SSF53474 403 505 3.29E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06280 161c4f5494eae223d842adf771c94513 540 Pfam PF00561 alpha/beta hydrolase fold 127 501 9.6E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS26790 23b49ddefa220a8a85f01c146ef915d0 132 SUPERFAMILY SSF53927 8 131 2.11E-41 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMD44_RS26790 23b49ddefa220a8a85f01c146ef915d0 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 14 103 1.2E-10 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SMD44_RS26790 23b49ddefa220a8a85f01c146ef915d0 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 11 130 2.5E-34 T 28-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 SMD44_RS26790 23b49ddefa220a8a85f01c146ef915d0 132 Gene3D G3DSA:3.40.140.10 2 132 2.5E-39 T 28-03-2018 SMD44_RS26790 23b49ddefa220a8a85f01c146ef915d0 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 59 99 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMD44_RS23055 449eac7915c428f7ea055c68cff8ea80 250 Gene3D G3DSA:1.10.10.10 186 234 1.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23055 449eac7915c428f7ea055c68cff8ea80 250 SUPERFAMILY SSF55781 27 158 1.3E-12 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS23055 449eac7915c428f7ea055c68cff8ea80 250 PIRSF PIRSF036625 15 243 5.6E-34 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS23055 449eac7915c428f7ea055c68cff8ea80 250 SMART SM01012 174 232 1.7E-9 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS23055 449eac7915c428f7ea055c68cff8ea80 250 Pfam PF03861 ANTAR domain 188 232 1.9E-9 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS23055 449eac7915c428f7ea055c68cff8ea80 250 Gene3D G3DSA:3.30.450.40 11 161 1.2E-10 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 Gene3D G3DSA:3.40.50.920 635 773 6.4E-30 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 SUPERFAMILY SSF52922 629 774 3.14E-26 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 PIRSF PIRSF000156 4 774 1.3E-72 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 76 234 4.1E-12 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 Gene3D G3DSA:3.40.50.970 393 623 1.8E-39 T 28-03-2018 SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 Pfam PF02780 Transketolase, C-terminal domain 641 686 3.0E-7 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 SMART SM00861 410 614 2.0E-8 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 SUPERFAMILY SSF52518 405 614 3.83E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 Gene3D G3DSA:3.40.50.970 13 383 3.4E-47 T 28-03-2018 SMD44_RS01060 078645ddcd3ed40f08f043c6adbd560d 775 SUPERFAMILY SSF52518 14 363 1.53E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS08770 c5b3ccd7fcfee15a04c2762d5d9a406c 160 SUPERFAMILY SSF55729 16 157 1.42E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS08770 c5b3ccd7fcfee15a04c2762d5d9a406c 160 Gene3D G3DSA:3.40.630.30 10 149 3.2E-22 T 28-03-2018 SMD44_RS08770 c5b3ccd7fcfee15a04c2762d5d9a406c 160 Pfam PF13673 Acetyltransferase (GNAT) domain 62 145 1.4E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS23025 6d6b1ee908ec4a9ceef8d25184fceea2 376 Pfam PF14907 Uncharacterised nucleotidyltransferase 66 250 6.9E-9 T 28-03-2018 SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 Gene3D G3DSA:3.40.190.10 183 265 3.0E-15 T 28-03-2018 SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 Gene3D G3DSA:1.10.10.10 1 83 5.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 Gene3D G3DSA:3.40.190.10 89 182 1.5E-15 T 28-03-2018 SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 SUPERFAMILY SSF53850 90 294 4.71E-29 T 28-03-2018 SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 SUPERFAMILY SSF46785 1 84 3.71E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39440 cabc04c5d8f176cc14dc961dfcaa6959 302 Pfam PF03466 LysR substrate binding domain 88 291 2.0E-32 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS23825 bc08182847d70f4796472db46edb8156 349 SUPERFAMILY SSF52374 21 244 7.11E-85 T 28-03-2018 SMD44_RS23825 bc08182847d70f4796472db46edb8156 349 Hamap MF_00158 Pantothenate synthetase [panC]. 20 343 39.143 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMD44_RS23825 bc08182847d70f4796472db46edb8156 349 Pfam PF02569 Pantoate-beta-alanine ligase 25 341 2.4E-91 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMD44_RS23825 bc08182847d70f4796472db46edb8156 349 Gene3D G3DSA:3.30.1300.10 192 349 1.1E-38 T 28-03-2018 SMD44_RS23825 bc08182847d70f4796472db46edb8156 349 Gene3D G3DSA:3.40.50.620 11 191 1.3E-69 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS23825 bc08182847d70f4796472db46edb8156 349 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 33 232 1.1E-75 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMD44_RS23825 bc08182847d70f4796472db46edb8156 349 SUPERFAMILY SSF52374 289 345 1.65E-5 T 28-03-2018 SMD44_RS32495 11efad886039729da25c7b9bbb66e412 364 Pfam PF03969 AFG1-like ATPase 59 248 1.7E-40 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 SMD44_RS32495 11efad886039729da25c7b9bbb66e412 364 Pfam PF03969 AFG1-like ATPase 251 355 9.3E-16 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 SMD44_RS32495 11efad886039729da25c7b9bbb66e412 364 SUPERFAMILY SSF52540 98 207 1.95E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32495 11efad886039729da25c7b9bbb66e412 364 Gene3D G3DSA:3.40.50.300 31 224 8.4E-6 T 28-03-2018 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 Gene3D G3DSA:3.40.1390.20 206 343 2.4E-26 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 Pfam PF01515 Phosphate acetyl/butaryl transferase 366 683 1.8E-124 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 Gene3D G3DSA:3.40.718.10 384 672 6.7E-64 T 28-03-2018 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 683 1.9E-119 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 Pfam PF13500 AAA domain 3 202 2.9E-18 T 28-03-2018 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 PIRSF PIRSF006107 1 691 3.1E-177 T 28-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 SUPERFAMILY SSF53659 365 686 3.08E-93 T 28-03-2018 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 Gene3D G3DSA:3.40.50.300 1 205 2.8E-29 T 28-03-2018 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 SUPERFAMILY SSF75138 204 321 2.28E-19 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 Pfam PF07085 DRTGG domain 210 319 1.0E-21 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMD44_RS29230 96f21f49f3ea7188c8a8e0c3b5a51fdb 701 SUPERFAMILY SSF52540 4 213 1.59E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 Pfam PF00005 ABC transporter 30 169 4.7E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 Gene3D G3DSA:3.40.50.300 1 249 1.6E-70 T 28-03-2018 SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 SMART SM00382 38 266 2.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 Gene3D G3DSA:2.40.50.100 250 307 1.6E-9 T 28-03-2018 SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 44 366 8.9E-110 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 SUPERFAMILY SSF52540 14 250 1.24E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 SUPERFAMILY SSF50331 245 368 3.13E-18 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMD44_RS30720 8ee4b7f25f72ce8238dd348bc11e4615 387 Pfam PF08402 TOBE domain 288 368 1.0E-14 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMD44_RS05920 ca685b766862d3bd522ae4308fffd045 188 Gene3D G3DSA:1.10.357.10 73 186 2.8E-11 T 28-03-2018 SMD44_RS05920 ca685b766862d3bd522ae4308fffd045 188 Gene3D G3DSA:1.10.10.60 52 72 5.5E-9 T 28-03-2018 SMD44_RS05920 ca685b766862d3bd522ae4308fffd045 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05920 ca685b766862d3bd522ae4308fffd045 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05920 ca685b766862d3bd522ae4308fffd045 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 8.5E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05920 ca685b766862d3bd522ae4308fffd045 188 Gene3D G3DSA:1.10.10.60 2 51 2.7E-16 T 28-03-2018 SMD44_RS05920 ca685b766862d3bd522ae4308fffd045 188 SUPERFAMILY SSF46689 10 85 2.46E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS03565 019317e4a5c048fd21a61610e0806f9e 328 Pfam PF03640 Secreted repeat of unknown function 111 146 3.2E-12 T 28-03-2018 IPR005297 Lipoprotein repeat SMD44_RS03565 019317e4a5c048fd21a61610e0806f9e 328 Pfam PF03640 Secreted repeat of unknown function 166 205 5.3E-17 T 28-03-2018 IPR005297 Lipoprotein repeat SMD44_RS03565 019317e4a5c048fd21a61610e0806f9e 328 Gene3D G3DSA:3.40.190.10 1 291 3.7E-6 T 28-03-2018 SMD44_RS03565 019317e4a5c048fd21a61610e0806f9e 328 Gene3D G3DSA:2.60.20.10 292 327 4.7E-5 T 28-03-2018 SMD44_RS16240 22d68553458678312757eb67b4d3c7be 188 Gene3D G3DSA:3.40.50.880 1 186 1.8E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS16240 22d68553458678312757eb67b4d3c7be 188 SUPERFAMILY SSF52317 1 181 4.08E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS16240 22d68553458678312757eb67b4d3c7be 188 Pfam PF01965 DJ-1/PfpI family 4 178 3.9E-46 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS16240 22d68553458678312757eb67b4d3c7be 188 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 181 2.2E-49 T 28-03-2018 IPR006286 Peptidase C56, PfpI SMD44_RS26020 cd37c4d3dbe27738e5948383809f9d41 426 SUPERFAMILY SSF47413 16 63 2.08E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS26020 cd37c4d3dbe27738e5948383809f9d41 426 SUPERFAMILY SSF88659 247 309 6.17E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26020 cd37c4d3dbe27738e5948383809f9d41 426 SUPERFAMILY SSF88946 165 231 1.65E-6 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26020 cd37c4d3dbe27738e5948383809f9d41 426 SMART SM00530 14 69 4.7E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS26020 cd37c4d3dbe27738e5948383809f9d41 426 Gene3D G3DSA:1.10.260.40 16 104 9.8E-15 T 28-03-2018 SMD44_RS26020 cd37c4d3dbe27738e5948383809f9d41 426 Gene3D G3DSA:1.10.1740.10 155 231 1.1E-8 T 28-03-2018 SMD44_RS26020 cd37c4d3dbe27738e5948383809f9d41 426 Pfam PF01381 Helix-turn-helix 16 62 3.7E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS26020 cd37c4d3dbe27738e5948383809f9d41 426 Gene3D G3DSA:1.10.10.10 232 316 1.9E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09255 163830744aaafabab93cfba76afdfd01 213 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 10 201 2.5E-48 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD44_RS09255 163830744aaafabab93cfba76afdfd01 213 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 13 198 1.5E-62 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD44_RS09255 163830744aaafabab93cfba76afdfd01 213 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 12 201 33.719 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD44_RS09255 163830744aaafabab93cfba76afdfd01 213 SUPERFAMILY SSF50486 8 206 4.55E-58 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMD44_RS09255 163830744aaafabab93cfba76afdfd01 213 Gene3D G3DSA:3.10.300.10 6 209 1.3E-72 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 44 60 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 11 574 6.0E-252 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 SUPERFAMILY SSF51569 26 337 1.61E-89 T 28-03-2018 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 250 263 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 SUPERFAMILY SSF110921 472 572 1.44E-35 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 9 574 54.638 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 Pfam PF08502 LeuA allosteric (dimerisation) domain 439 572 5.3E-37 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 Pfam PF00682 HMGL-like 37 318 4.7E-71 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 Gene3D G3DSA:3.20.20.70 14 393 1.5E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 SMART SM00917 439 573 3.8E-40 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS13690 14f39848aeb2aede24b4cd24971937c0 574 SUPERFAMILY SSF89000 405 454 1.14E-15 T 28-03-2018 SMD44_RS12735 58ea01d4f36848271c7760055b95deff 335 Pfam PF00248 Aldo/keto reductase family 19 314 4.2E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS12735 58ea01d4f36848271c7760055b95deff 335 Gene3D G3DSA:3.20.20.100 3 333 2.1E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS12735 58ea01d4f36848271c7760055b95deff 335 SUPERFAMILY SSF51430 5 315 2.23E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 383 1.5E-125 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 Pfam PF00108 Thiolase, N-terminal domain 5 254 1.7E-58 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 ProSitePatterns PS00737 Thiolases signature 2. 331 347 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 SUPERFAMILY SSF53901 3 262 2.76E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 SUPERFAMILY SSF53901 263 384 2.98E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 PIRSF PIRSF000429 1 385 4.1E-121 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 Gene3D G3DSA:3.40.47.10 265 382 5.5E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 Gene3D G3DSA:3.40.47.10 157 264 2.8E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 Gene3D G3DSA:3.40.47.10 1 153 1.6E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35125 91cea6d8c2bb82739df0753efef9eabb 385 Pfam PF02803 Thiolase, C-terminal domain 263 384 8.9E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD44_RS41390 fcf615358ec4bc3d8f2bb690f88c0e84 185 Pfam PF13787 Protein of unknown function with HXXEE motif 21 140 1.8E-17 T 28-03-2018 IPR025671 Protein of unknown function with HXXEE motif SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Pfam PF08335 GlnD PII-uridylyltransferase 852 992 4.6E-19 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Pfam PF08335 GlnD PII-uridylyltransferase 338 478 3.7E-37 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 86 985 17.083 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 SUPERFAMILY SSF81593 844 994 7.38E-35 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Gene3D G3DSA:3.30.460.10 678 837 1.9E-50 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Gene3D G3DSA:3.30.460.10 164 324 5.8E-59 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 SUPERFAMILY SSF81301 61 324 3.92E-68 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 SUPERFAMILY SSF81301 555 838 3.27E-59 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 583 828 2.0E-42 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 90 315 4.4E-48 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Gene3D G3DSA:1.20.120.330 327 482 2.5E-51 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Gene3D G3DSA:1.20.120.330 840 997 3.8E-46 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 SUPERFAMILY SSF81593 330 479 1.49E-40 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Gene3D G3DSA:1.10.4050.10 558 663 1.1E-17 T 28-03-2018 SMD44_RS11855 39358891cb87d19a32428107f49555e2 997 Gene3D G3DSA:1.10.4050.10 61 163 1.3E-17 T 28-03-2018 SMD44_RS06255 24b23db7830dd4ed5f85b8b2b7d9319b 184 Gene3D G3DSA:3.90.960.10 23 181 5.0E-23 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS06255 24b23db7830dd4ed5f85b8b2b7d9319b 184 SUPERFAMILY SSF55826 37 179 6.02E-21 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS06255 24b23db7830dd4ed5f85b8b2b7d9319b 184 Pfam PF04073 Aminoacyl-tRNA editing domain 66 166 7.1E-13 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS07230 dd74acc45f6f1567967c38d19883d383 90 SMART SM01409 18 82 2.2E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMD44_RS07230 dd74acc45f6f1567967c38d19883d383 90 SUPERFAMILY SSF63562 11 87 7.5E-25 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMD44_RS07230 dd74acc45f6f1567967c38d19883d383 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 12 80 8.5E-22 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS07230 dd74acc45f6f1567967c38d19883d383 90 Gene3D G3DSA:3.90.940.10 11 89 2.5E-21 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMD44_RS07230 dd74acc45f6f1567967c38d19883d383 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.945 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS07230 dd74acc45f6f1567967c38d19883d383 90 Pfam PF01192 RNA polymerase Rpb6 18 80 1.0E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMD44_RS06085 09812e05836c73fee8261acff58bed9c 149 SUPERFAMILY SSF52821 24 126 3.4E-24 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS06085 09812e05836c73fee8261acff58bed9c 149 SMART SM00450 26 123 5.7E-15 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS06085 09812e05836c73fee8261acff58bed9c 149 Gene3D G3DSA:3.40.250.10 7 126 8.0E-23 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS06085 09812e05836c73fee8261acff58bed9c 149 Pfam PF00581 Rhodanese-like domain 35 119 1.3E-12 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS15230 a675ecb9d9dbf5faa14b007aa116d523 457 SUPERFAMILY SSF51569 15 455 2.78E-187 T 28-03-2018 SMD44_RS15230 a675ecb9d9dbf5faa14b007aa116d523 457 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 19 455 1.3E-208 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD44_RS15230 a675ecb9d9dbf5faa14b007aa116d523 457 Pfam PF01474 Class-II DAHP synthetase family 19 451 1.4E-189 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD44_RS01140 399f26e283fd5d1845a2abbf7750ba33 200 Gene3D G3DSA:1.20.120.450 25 200 2.6E-33 T 28-03-2018 SMD44_RS01140 399f26e283fd5d1845a2abbf7750ba33 200 Pfam PF04978 Protein of unknown function (DUF664) 49 196 1.4E-45 T 28-03-2018 IPR007061 Protein of unknown function DUF664 SMD44_RS01140 399f26e283fd5d1845a2abbf7750ba33 200 SUPERFAMILY SSF109854 33 195 2.44E-39 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS06820 b5c6d1500e3fc203376fe1fb43acdb3b 254 Pfam PF03746 LamB/YcsF family 6 244 1.3E-96 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF SMD44_RS06820 b5c6d1500e3fc203376fe1fb43acdb3b 254 SUPERFAMILY SSF88713 5 253 2.3E-92 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS06820 b5c6d1500e3fc203376fe1fb43acdb3b 254 Gene3D G3DSA:3.20.20.370 5 252 2.6E-103 T 28-03-2018 SMD44_RS06820 b5c6d1500e3fc203376fe1fb43acdb3b 254 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 4 248 43.306 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF SMD44_RS09485 910c78f3ccecfa8ba8b4d566b476ae7a 372 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 48 204 2.2E-26 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS09485 910c78f3ccecfa8ba8b4d566b476ae7a 372 Gene3D G3DSA:3.40.50.10190 236 359 8.1E-10 T 28-03-2018 IPR001357 BRCT domain SMD44_RS09485 910c78f3ccecfa8ba8b4d566b476ae7a 372 Pfam PF00929 Exonuclease 50 202 4.8E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS09485 910c78f3ccecfa8ba8b4d566b476ae7a 372 SMART SM00479 47 211 6.1E-33 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS09485 910c78f3ccecfa8ba8b4d566b476ae7a 372 SUPERFAMILY SSF52113 279 357 2.26E-10 T 28-03-2018 IPR001357 BRCT domain SMD44_RS09485 910c78f3ccecfa8ba8b4d566b476ae7a 372 SUPERFAMILY SSF53098 45 208 4.18E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS09485 910c78f3ccecfa8ba8b4d566b476ae7a 372 Gene3D G3DSA:3.30.420.10 33 211 1.5E-32 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.3E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 Gene3D G3DSA:3.40.50.2300 1 125 1.4E-32 T 28-03-2018 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 7.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 7.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 7.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 Pfam PF00072 Response regulator receiver domain 4 116 6.1E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 SUPERFAMILY SSF52172 1 129 1.71E-29 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 SUPERFAMILY SSF46894 124 201 3.33E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 SMART SM00421 138 195 1.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 Gene3D G3DSA:1.10.10.10 126 201 3.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS12280 27c4e0e3b86b7051ba2a51bf5dec51f9 201 SMART SM00448 2 115 1.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26490 288147739dd86492a7c53cb00adfaee3 235 SMART SM00448 13 123 1.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26490 288147739dd86492a7c53cb00adfaee3 235 Gene3D G3DSA:1.10.10.10 133 235 1.8E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26490 288147739dd86492a7c53cb00adfaee3 235 SMART SM00862 160 234 7.0E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS26490 288147739dd86492a7c53cb00adfaee3 235 Pfam PF00072 Response regulator receiver domain 15 123 7.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26490 288147739dd86492a7c53cb00adfaee3 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 233 3.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS26490 288147739dd86492a7c53cb00adfaee3 235 SUPERFAMILY SSF52172 12 181 3.58E-33 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS26490 288147739dd86492a7c53cb00adfaee3 235 Gene3D G3DSA:3.40.50.2300 2 132 1.2E-31 T 28-03-2018 SMD44_RS22750 2c0374f5c6049588613615765791ed4a 815 Pfam PF00535 Glycosyl transferase family 2 6 141 4.1E-29 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS22750 2c0374f5c6049588613615765791ed4a 815 Gene3D G3DSA:3.90.550.10 2 304 5.3E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS22750 2c0374f5c6049588613615765791ed4a 815 SUPERFAMILY SSF53448 4 223 9.96E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS18810 2dbc4118a8af5596b67be597dd523c86 327 Pfam PF00535 Glycosyl transferase family 2 36 158 2.4E-8 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS18810 2dbc4118a8af5596b67be597dd523c86 327 Gene3D G3DSA:3.90.550.10 1 327 3.2E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS18810 2dbc4118a8af5596b67be597dd523c86 327 SUPERFAMILY SSF53448 35 295 4.02E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS17430 b605d2d2deb5a5abb210ef72b70bbfed 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS17430 b605d2d2deb5a5abb210ef72b70bbfed 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS17430 b605d2d2deb5a5abb210ef72b70bbfed 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS17430 b605d2d2deb5a5abb210ef72b70bbfed 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS17430 b605d2d2deb5a5abb210ef72b70bbfed 175 Pfam PF12802 MarR family 51 111 3.3E-12 T 28-03-2018 SMD44_RS17430 b605d2d2deb5a5abb210ef72b70bbfed 175 SMART SM00347 45 148 1.2E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS17430 b605d2d2deb5a5abb210ef72b70bbfed 175 Gene3D G3DSA:1.10.10.10 1 165 5.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17430 b605d2d2deb5a5abb210ef72b70bbfed 175 SUPERFAMILY SSF46785 15 162 1.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12105 1003351175c129955ab6da649e3dd7a0 334 Gene3D G3DSA:3.40.50.150 21 310 7.9E-9 T 28-03-2018 SMD44_RS12105 1003351175c129955ab6da649e3dd7a0 334 SUPERFAMILY SSF53335 54 217 4.42E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS12105 1003351175c129955ab6da649e3dd7a0 334 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 53 330 3.0E-100 T 28-03-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Pfam PF00512 His Kinase A (phospho-acceptor) domain 617 683 4.7E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Gene3D G3DSA:3.30.450.40 480 570 0.027 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 SUPERFAMILY SSF55874 674 834 1.7E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Gene3D G3DSA:3.40.50.620 208 355 7.2E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Pfam PF13493 Domain of unknown function (DUF4118) 384 489 4.5E-23 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 SMART SM00388 616 684 1.3E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Gene3D G3DSA:1.10.287.130 606 679 1.6E-16 T 28-03-2018 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 SUPERFAMILY SSF52402 231 348 1.57E-8 T 28-03-2018 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 SMART SM00387 726 836 1.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 727 834 6.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Gene3D G3DSA:3.40.50.300 2 128 5.3E-23 T 28-03-2018 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 7.5E-100 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Gene3D G3DSA:3.30.450.40 571 605 8.0E-4 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 796 814 3.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 820 833 3.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 781 791 3.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 763 777 3.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Gene3D G3DSA:1.20.120.620 383 479 6.2E-24 T 28-03-2018 SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 Gene3D G3DSA:3.30.565.10 680 836 4.6E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05405 948bd48b30bd2bd23a2f17e57c0e2d7b 851 SUPERFAMILY SSF47384 605 684 1.08E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 SMART SM00487 17 300 0.0017 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 SMART SM00491 488 617 2.7E-42 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 Pfam PF13307 Helicase C-terminal domain 471 630 2.7E-28 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 Gene3D G3DSA:3.40.50.300 460 652 2.0E-9 T 28-03-2018 SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 SUPERFAMILY SSF52540 189 260 4.1E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 SUPERFAMILY SSF52540 392 406 4.1E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 SUPERFAMILY SSF52540 445 600 4.1E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 SUPERFAMILY SSF52540 35 85 4.1E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31420 2bf2e26c1c75f1ed79ffaa1d79a5c8c4 671 Gene3D G3DSA:3.40.50.300 20 417 7.1E-26 T 28-03-2018 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 Gene3D G3DSA:3.40.50.300 75 190 1.5E-24 T 28-03-2018 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 SUPERFAMILY SSF52540 8 225 2.39E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 390 9.7E-172 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.5E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.5E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 Gene3D G3DSA:2.40.30.10 299 390 3.5E-25 T 28-03-2018 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 Gene3D G3DSA:2.40.30.10 191 297 7.9E-27 T 28-03-2018 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 SUPERFAMILY SSF50465 302 390 1.92E-25 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 Gene3D G3DSA:3.40.50.300 3 74 2.3E-11 T 28-03-2018 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 Pfam PF00009 Elongation factor Tu GTP binding domain 10 200 8.6E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 Pfam PF03144 Elongation factor Tu domain 2 224 292 1.3E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 SUPERFAMILY SSF50447 204 300 1.49E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 391 52.491 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 145 1.4E-12 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SMD44_RS06340 dfe9f00a2a44195f9157ee5a8c6be38a 391 Pfam PF03143 Elongation factor Tu C-terminal domain 299 390 9.2E-22 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SMD44_RS15265 ad9d75d82206966d1d67cb11d5fe4bd1 481 Gene3D G3DSA:3.30.565.10 281 457 9.3E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15265 ad9d75d82206966d1d67cb11d5fe4bd1 481 SUPERFAMILY SSF55874 290 384 2.39E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15265 ad9d75d82206966d1d67cb11d5fe4bd1 481 SUPERFAMILY SSF55874 420 455 2.39E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15265 ad9d75d82206966d1d67cb11d5fe4bd1 481 Pfam PF07730 Histidine kinase 195 260 1.1E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS10280 5a2d72a87110d731ba45543acaa51865 347 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 286 299 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD44_RS10280 5a2d72a87110d731ba45543acaa51865 347 Gene3D G3DSA:3.40.1190.20 18 335 7.0E-59 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS10280 5a2d72a87110d731ba45543acaa51865 347 SUPERFAMILY SSF53613 20 331 3.12E-58 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS10280 5a2d72a87110d731ba45543acaa51865 347 Pfam PF00294 pfkB family carbohydrate kinase 20 330 6.7E-42 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS07330 58a802f62119ea662db55e2577a29201 276 Gene3D G3DSA:3.40.50.10860 1 116 8.5E-43 T 28-03-2018 SMD44_RS07330 58a802f62119ea662db55e2577a29201 276 SUPERFAMILY SSF53223 6 105 3.22E-27 T 28-03-2018 SMD44_RS07330 58a802f62119ea662db55e2577a29201 276 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 92 5.4E-25 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SMD44_RS07330 58a802f62119ea662db55e2577a29201 276 Gene3D G3DSA:3.40.50.720 117 275 9.8E-24 T 28-03-2018 SMD44_RS07330 58a802f62119ea662db55e2577a29201 276 SUPERFAMILY SSF51735 106 268 9.67E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 Pfam PF11941 Domain of unknown function (DUF3459) 479 570 1.0E-10 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 Gene3D G3DSA:2.60.40.1180 505 571 1.3E-7 T 28-03-2018 SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 Gene3D G3DSA:3.20.20.470 1 116 8.4E-35 T 28-03-2018 SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 Gene3D G3DSA:3.20.20.80 362 496 5.2E-29 T 28-03-2018 SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 Gene3D G3DSA:3.90.400.10 126 198 8.3E-27 T 28-03-2018 SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 SMART SM00642 34 431 8.9E-127 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 Pfam PF00128 Alpha amylase, catalytic domain 49 396 7.9E-78 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 Gene3D G3DSA:3.20.20.470 199 361 1.5E-37 T 28-03-2018 SMD44_RS11840 ec8ce690e53471ff83d66c284394478e 572 SUPERFAMILY SSF51445 26 493 1.8E-130 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS25865 060cce4e4248e7e5e632aba2a3cf6f66 564 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS25865 060cce4e4248e7e5e632aba2a3cf6f66 564 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS25865 060cce4e4248e7e5e632aba2a3cf6f66 564 SMART SM00220 13 269 3.1E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25865 060cce4e4248e7e5e632aba2a3cf6f66 564 SUPERFAMILY SSF56112 7 265 1.62E-64 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS25865 060cce4e4248e7e5e632aba2a3cf6f66 564 Gene3D G3DSA:3.30.200.20 2 100 2.1E-20 T 28-03-2018 SMD44_RS25865 060cce4e4248e7e5e632aba2a3cf6f66 564 Gene3D G3DSA:1.10.510.10 101 304 7.4E-44 T 28-03-2018 SMD44_RS25865 060cce4e4248e7e5e632aba2a3cf6f66 564 Pfam PF00069 Protein kinase domain 13 262 2.9E-44 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS27240 0febc88778b5cb82aed0d307a0e4a14f 250 SMART SM00346 2 89 2.2E-24 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS27240 0febc88778b5cb82aed0d307a0e4a14f 250 Gene3D G3DSA:1.10.10.10 1 73 2.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27240 0febc88778b5cb82aed0d307a0e4a14f 250 SUPERFAMILY SSF55781 57 243 8.83E-49 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS27240 0febc88778b5cb82aed0d307a0e4a14f 250 SUPERFAMILY SSF46785 3 72 1.41E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27240 0febc88778b5cb82aed0d307a0e4a14f 250 Pfam PF09339 IclR helix-turn-helix domain 4 49 6.3E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS27240 0febc88778b5cb82aed0d307a0e4a14f 250 Gene3D G3DSA:3.30.450.40 74 250 8.1E-51 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS27240 0febc88778b5cb82aed0d307a0e4a14f 250 Pfam PF01614 Bacterial transcriptional regulator 117 241 4.3E-30 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS06780 af464f3331bc87a20a68d32bfd30243e 395 Hamap MF_00516 Monomeric sarcosine oxidase [soxA]. 4 392 63.903 T 28-03-2018 IPR006281 Sarcosine oxidase, monomeric GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722|Reactome: R-HSA-71064 SMD44_RS06780 af464f3331bc87a20a68d32bfd30243e 395 SUPERFAMILY SSF54373 220 324 1.65E-23 T 28-03-2018 SMD44_RS06780 af464f3331bc87a20a68d32bfd30243e 395 Gene3D G3DSA:3.40.50.720 2 43 2.8E-5 T 28-03-2018 SMD44_RS06780 af464f3331bc87a20a68d32bfd30243e 395 Pfam PF01266 FAD dependent oxidoreductase 9 364 1.5E-46 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS06780 af464f3331bc87a20a68d32bfd30243e 395 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 12 25 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS06780 af464f3331bc87a20a68d32bfd30243e 395 SUPERFAMILY SSF51905 7 221 2.55E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06780 af464f3331bc87a20a68d32bfd30243e 395 SUPERFAMILY SSF51905 324 382 2.55E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06780 af464f3331bc87a20a68d32bfd30243e 395 Gene3D G3DSA:3.30.9.10 64 324 3.3E-41 T 28-03-2018 SMD44_RS26700 30aa49cf65267036484f2ccbb9fe9cde 1222 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 71 249 5.0E-5 T 28-03-2018 SMD44_RS26700 30aa49cf65267036484f2ccbb9fe9cde 1222 SUPERFAMILY SSF49899 798 997 8.45E-23 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS26700 30aa49cf65267036484f2ccbb9fe9cde 1222 SUPERFAMILY SSF49899 983 1208 3.96E-15 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS26700 30aa49cf65267036484f2ccbb9fe9cde 1222 SMART SM00560 822 969 9.3E-9 T 28-03-2018 IPR006558 LamG-like jellyroll fold SMD44_RS26700 30aa49cf65267036484f2ccbb9fe9cde 1222 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 806 970 1.3E-27 T 28-03-2018 SMD44_RS26700 30aa49cf65267036484f2ccbb9fe9cde 1222 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1042 1203 1.4E-13 T 28-03-2018 SMD44_RS26700 30aa49cf65267036484f2ccbb9fe9cde 1222 Gene3D G3DSA:2.60.120.200 981 1218 1.2E-23 T 28-03-2018 SMD44_RS26700 30aa49cf65267036484f2ccbb9fe9cde 1222 Gene3D G3DSA:2.60.120.200 751 975 1.2E-31 T 28-03-2018 SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 Gene3D G3DSA:3.40.50.720 8 247 3.3E-69 T 28-03-2018 SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 SUPERFAMILY SSF51735 1 243 2.64E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37195 e18f42f3abe5e976eb52c4ebd673dbbf 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 2.3E-58 T 28-03-2018 SMD44_RS08375 bf39af736bd825ad766c054c6b079e5c 412 SUPERFAMILY SSF56349 65 398 5.21E-41 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS08375 bf39af736bd825ad766c054c6b079e5c 412 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 66 116 3.1E-6 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMD44_RS08375 bf39af736bd825ad766c054c6b079e5c 412 Pfam PF00589 Phage integrase family 214 388 6.4E-10 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS08375 bf39af736bd825ad766c054c6b079e5c 412 Gene3D G3DSA:1.10.443.10 181 400 2.9E-27 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS08375 bf39af736bd825ad766c054c6b079e5c 412 Gene3D G3DSA:1.10.150.130 58 180 1.0E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 Gene3D G3DSA:3.60.40.10 632 890 1.3E-43 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 Pfam PF13185 GAF domain 464 626 1.3E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SUPERFAMILY SSF55781 537 638 1.26E-13 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 Gene3D G3DSA:3.30.450.20 320 440 1.9E-19 T 28-03-2018 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SUPERFAMILY SSF55874 925 1012 7.11E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SUPERFAMILY SSF81606 669 889 9.42E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SMART SM00065 501 635 2.9E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 Gene3D G3DSA:3.30.450.20 176 316 3.7E-15 T 28-03-2018 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 682 889 1.6E-50 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 Pfam PF08448 PAS fold 327 437 7.1E-24 T 28-03-2018 IPR013656 PAS fold-4 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SMART SM00331 656 888 6.9E-46 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 Gene3D G3DSA:3.30.565.10 893 1027 1.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SUPERFAMILY SSF55785 177 251 1.18E-8 T 28-03-2018 IPR000014 PAS domain SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 Gene3D G3DSA:3.30.450.40 441 631 4.7E-37 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SUPERFAMILY SSF55785 312 434 4.64E-14 T 28-03-2018 IPR000014 PAS domain SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 177 248 6.0E-6 T 28-03-2018 IPR000014 PAS domain SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 324 442 1.8E-7 T 28-03-2018 IPR000014 PAS domain SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SMART SM00091 320 386 0.0097 T 28-03-2018 IPR000014 PAS domain SMD44_RS27640 3fcf3dd29ddd43ab2c4d5a13f3073adf 1032 SMART SM00091 173 240 3.4E-4 T 28-03-2018 IPR000014 PAS domain SMD44_RS07245 1fc3a9bb320197c1e27a2417f2d1ba47 281 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 7 266 2.4E-82 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07245 1fc3a9bb320197c1e27a2417f2d1ba47 281 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 5 280 33.858 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07245 1fc3a9bb320197c1e27a2417f2d1ba47 281 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 20 264 1.4E-35 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07245 1fc3a9bb320197c1e27a2417f2d1ba47 281 Gene3D G3DSA:3.20.20.70 6 281 7.1E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS07245 1fc3a9bb320197c1e27a2417f2d1ba47 281 SMART SM00934 20 266 4.5E-33 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07245 1fc3a9bb320197c1e27a2417f2d1ba47 281 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 94 107 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07245 1fc3a9bb320197c1e27a2417f2d1ba47 281 SUPERFAMILY SSF51366 7 270 1.32E-60 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD44_RS35880 62ad537d0098ab3c9b3db15f958a2fe6 131 Pfam PF01807 CHC2 zinc finger 11 86 1.9E-11 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD44_RS35880 62ad537d0098ab3c9b3db15f958a2fe6 131 Gene3D G3DSA:3.90.580.10 3 92 8.9E-19 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD44_RS35880 62ad537d0098ab3c9b3db15f958a2fe6 131 SUPERFAMILY SSF57783 10 89 3.06E-17 T 28-03-2018 SMD44_RS35880 62ad537d0098ab3c9b3db15f958a2fe6 131 SMART SM00400 30 84 9.4E-8 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD44_RS00465 9c192d25251b6d6be1986dfb9f59277c 256 SMART SM00849 23 200 0.0062 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS00465 9c192d25251b6d6be1986dfb9f59277c 256 Gene3D G3DSA:3.60.15.10 6 256 8.2E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS00465 9c192d25251b6d6be1986dfb9f59277c 256 SUPERFAMILY SSF56281 7 254 3.93E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS00465 9c192d25251b6d6be1986dfb9f59277c 256 Pfam PF12706 Beta-lactamase superfamily domain 34 222 2.5E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 Pfam PF00067 Cytochrome P450 23 427 4.2E-75 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00385 P450 superfamily signature 252 269 1.8E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00385 P450 superfamily signature 389 400 1.8E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00385 P450 superfamily signature 380 389 1.8E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00385 P450 superfamily signature 305 316 1.8E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 Gene3D G3DSA:1.10.630.10 19 440 4.6E-103 T 28-03-2018 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00463 E-class P450 group I signature 389 412 2.5E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00463 E-class P450 group I signature 34 53 2.5E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00463 E-class P450 group I signature 261 287 2.5E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00463 E-class P450 group I signature 344 368 2.5E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00463 E-class P450 group I signature 304 322 2.5E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 PRINTS PR00463 E-class P450 group I signature 379 389 2.5E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02210 459a0869d943f40a9f257fc71c11c131 444 SUPERFAMILY SSF48264 5 441 8.64E-94 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS24140 6c8b36c6e242739cd6e6c83e3b01eec3 254 Gene3D G3DSA:1.10.10.10 14 84 8.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24140 6c8b36c6e242739cd6e6c83e3b01eec3 254 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 11 219 36.611 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 SMD44_RS24140 6c8b36c6e242739cd6e6c83e3b01eec3 254 Pfam PF02629 CoA binding domain 91 188 2.0E-21 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS24140 6c8b36c6e242739cd6e6c83e3b01eec3 254 Pfam PF06971 Putative DNA-binding protein N-terminus 16 63 3.8E-19 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 SMD44_RS24140 6c8b36c6e242739cd6e6c83e3b01eec3 254 SUPERFAMILY SSF51735 93 214 2.07E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24140 6c8b36c6e242739cd6e6c83e3b01eec3 254 SUPERFAMILY SSF46785 17 89 1.25E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24140 6c8b36c6e242739cd6e6c83e3b01eec3 254 SMART SM00881 89 190 3.5E-17 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS24140 6c8b36c6e242739cd6e6c83e3b01eec3 254 Gene3D G3DSA:3.40.50.720 87 229 6.1E-20 T 28-03-2018 SMD44_RS34920 8af0314610d400215fbf3323615a1641 340 SMART SM00829 8 317 5.7E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS34920 8af0314610d400215fbf3323615a1641 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 97 3.1E-12 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS34920 8af0314610d400215fbf3323615a1641 340 SUPERFAMILY SSF51735 112 266 4.15E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34920 8af0314610d400215fbf3323615a1641 340 SUPERFAMILY SSF50129 14 145 3.96E-30 T 28-03-2018 IPR011032 GroES-like SMD44_RS34920 8af0314610d400215fbf3323615a1641 340 Gene3D G3DSA:3.40.50.720 149 265 1.1E-16 T 28-03-2018 SMD44_RS34920 8af0314610d400215fbf3323615a1641 340 Gene3D G3DSA:3.90.180.10 6 148 5.3E-33 T 28-03-2018 SMD44_RS34920 8af0314610d400215fbf3323615a1641 340 Pfam PF00107 Zinc-binding dehydrogenase 146 259 1.2E-12 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS34920 8af0314610d400215fbf3323615a1641 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS10530 58bc3d3811e4a8c934b8e7a1cda268d6 410 Gene3D G3DSA:3.40.50.2300 33 212 4.5E-34 T 28-03-2018 SMD44_RS10530 58bc3d3811e4a8c934b8e7a1cda268d6 410 Gene3D G3DSA:3.40.50.2300 214 390 4.8E-25 T 28-03-2018 SMD44_RS10530 58bc3d3811e4a8c934b8e7a1cda268d6 410 Pfam PF13458 Periplasmic binding protein 41 396 3.4E-55 T 28-03-2018 IPR028081 Leucine-binding protein domain SMD44_RS10530 58bc3d3811e4a8c934b8e7a1cda268d6 410 SUPERFAMILY SSF53822 41 400 5.72E-80 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS29130 58fd87b0114ab2eaf34f1e0318a203a2 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS29130 58fd87b0114ab2eaf34f1e0318a203a2 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 3.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS29130 58fd87b0114ab2eaf34f1e0318a203a2 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 3.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS29130 58fd87b0114ab2eaf34f1e0318a203a2 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 3.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS29130 58fd87b0114ab2eaf34f1e0318a203a2 168 SMART SM00347 48 149 5.8E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS29130 58fd87b0114ab2eaf34f1e0318a203a2 168 Pfam PF12802 MarR family 53 114 4.1E-12 T 28-03-2018 SMD44_RS29130 58fd87b0114ab2eaf34f1e0318a203a2 168 SUPERFAMILY SSF46785 27 159 5.15E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29130 58fd87b0114ab2eaf34f1e0318a203a2 168 Gene3D G3DSA:1.10.10.10 12 165 3.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03140 e8691f3d625e431b2c8a35e5e949f19b 362 Gene3D G3DSA:3.40.640.10 50 255 6.5E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS03140 e8691f3d625e431b2c8a35e5e949f19b 362 SUPERFAMILY SSF53383 27 359 1.22E-73 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS03140 e8691f3d625e431b2c8a35e5e949f19b 362 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 17 357 4.1E-86 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD44_RS03140 e8691f3d625e431b2c8a35e5e949f19b 362 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 15 361 49.652 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD44_RS03140 e8691f3d625e431b2c8a35e5e949f19b 362 Pfam PF00155 Aminotransferase class I and II 39 355 1.3E-48 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS03140 e8691f3d625e431b2c8a35e5e949f19b 362 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 16 362 45.215 T 28-03-2018 IPR024892 Putative phenylalanine aminotransferase SMD44_RS03140 e8691f3d625e431b2c8a35e5e949f19b 362 Gene3D G3DSA:3.90.1150.10 256 361 2.0E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 156 183 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 1.7E-121 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 Gene3D G3DSA:3.40.50.261 124 295 3.7E-48 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 SMART SM00881 4 104 3.2E-24 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 Pfam PF00549 CoA-ligase 156 272 1.3E-13 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 4.8E-33 T 28-03-2018 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 PRINTS PR01798 Succinyl-CoA synthase signature 179 197 4.8E-33 T 28-03-2018 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 PRINTS PR01798 Succinyl-CoA synthase signature 242 259 4.8E-33 T 28-03-2018 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 PRINTS PR01798 Succinyl-CoA synthase signature 210 223 4.8E-33 T 28-03-2018 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 SUPERFAMILY SSF51735 1 126 4.22E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 SUPERFAMILY SSF52210 127 286 1.44E-45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 290 38.507 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 Pfam PF02629 CoA binding domain 6 103 1.8E-23 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 PIRSF PIRSF001553 1 293 2.1E-113 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 238 251 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site SMD44_RS34815 e0a4d4c1b2176904e728b629cf067691 295 Gene3D G3DSA:3.40.50.720 1 123 4.1E-39 T 28-03-2018 SMD44_RS29365 012e1160798cd3ff8663b8f11641a214 406 SUPERFAMILY SSF53383 22 387 3.71E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS29365 012e1160798cd3ff8663b8f11641a214 406 Pfam PF00155 Aminotransferase class I and II 51 386 1.5E-58 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS29365 012e1160798cd3ff8663b8f11641a214 406 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 244 253 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD44_RS29365 012e1160798cd3ff8663b8f11641a214 406 Gene3D G3DSA:3.40.640.10 64 289 3.7E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS29365 012e1160798cd3ff8663b8f11641a214 406 Gene3D G3DSA:3.90.1150.10 290 389 1.3E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 2.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 2.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 2.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 SMART SM00448 3 118 1.1E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 Pfam PF00072 Response regulator receiver domain 5 118 6.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 Gene3D G3DSA:1.10.10.10 130 225 9.9E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 Gene3D G3DSA:3.40.50.2300 2 129 5.8E-32 T 28-03-2018 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 SUPERFAMILY SSF46894 154 221 2.52E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 SMART SM00421 158 215 3.4E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 SUPERFAMILY SSF52172 3 129 1.42E-31 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS11445 803904c6c3e11ba99e3dab52f4cc6f75 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 5.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS03135 0cbb8b021723bec615b46ca0242d591f 449 SUPERFAMILY SSF55205 4 433 3.53E-87 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD44_RS03135 0cbb8b021723bec615b46ca0242d591f 449 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 427 4.4E-78 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS03135 0cbb8b021723bec615b46ca0242d591f 449 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 13 430 4.1E-94 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD44_RS03135 0cbb8b021723bec615b46ca0242d591f 449 Gene3D G3DSA:3.65.10.10 224 441 1.1E-35 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS03135 0cbb8b021723bec615b46ca0242d591f 449 PIRSF PIRSF000505 1 437 6.0E-102 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD44_RS03135 0cbb8b021723bec615b46ca0242d591f 449 Gene3D G3DSA:3.65.10.10 21 223 1.7E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS03135 0cbb8b021723bec615b46ca0242d591f 449 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 9 434 26.071 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 SUPERFAMILY SSF56645 4 242 2.62E-83 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 SUPERFAMILY SSF47203 228 380 1.59E-44 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 Gene3D G3DSA:2.40.110.10 122 221 2.8E-39 T 28-03-2018 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 Gene3D G3DSA:1.20.140.10 222 380 9.6E-52 T 28-03-2018 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 1.5E-32 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 Gene3D G3DSA:1.10.540.10 1 121 7.7E-35 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 4.2E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS35340 fae4ea23fd94d112a64950ca9dcda793 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 379 1.2E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS17155 25e1bfc77f8d784562e8fe33318a6b4f 64 Pfam PF04149 Domain of unknown function (DUF397) 10 61 2.0E-17 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS25760 4f3ba3666351cdfff040ba76f94cf9e1 404 Gene3D G3DSA:3.40.50.150 52 261 3.0E-25 T 28-03-2018 SMD44_RS25760 4f3ba3666351cdfff040ba76f94cf9e1 404 Pfam PF09445 RNA cap guanine-N2 methyltransferase 111 168 2.7E-7 T 28-03-2018 IPR019012 RNA cap guanine-N2 methyltransferase GO:0001510|GO:0008168|GO:0009452 Reactome: R-HSA-1368082|Reactome: R-HSA-1368108|Reactome: R-HSA-191859|Reactome: R-HSA-1989781|Reactome: R-HSA-2032785|Reactome: R-HSA-2151201|Reactome: R-HSA-2426168|Reactome: R-HSA-381340|Reactome: R-HSA-400206|Reactome: R-HSA-400253|Reactome: R-HSA-8951671 SMD44_RS25760 4f3ba3666351cdfff040ba76f94cf9e1 404 SUPERFAMILY SSF53335 72 238 2.91E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS14195 b21ded398d81a9ceeaa2db4962c8e011 278 Pfam PF00005 ABC transporter 50 196 6.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS14195 b21ded398d81a9ceeaa2db4962c8e011 278 SUPERFAMILY SSF52540 31 249 8.28E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14195 b21ded398d81a9ceeaa2db4962c8e011 278 SMART SM00382 59 245 2.8E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14195 b21ded398d81a9ceeaa2db4962c8e011 278 Gene3D G3DSA:3.40.50.300 28 269 8.4E-66 T 28-03-2018 SMD44_RS14195 b21ded398d81a9ceeaa2db4962c8e011 278 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS25380 8114dbeab181de8322016102ef638034 477 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 418 7.8E-93 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS25380 8114dbeab181de8322016102ef638034 477 SUPERFAMILY SSF103473 7 197 1.2E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS25380 8114dbeab181de8322016102ef638034 477 SUPERFAMILY SSF103473 247 457 1.2E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS25380 8114dbeab181de8322016102ef638034 477 Pfam PF07690 Major Facilitator Superfamily 20 409 1.1E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS25380 8114dbeab181de8322016102ef638034 477 Gene3D G3DSA:1.20.1250.20 251 459 1.0E-33 T 28-03-2018 SMD44_RS25380 8114dbeab181de8322016102ef638034 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 1.8E-8 T 28-03-2018 SMD44_RS25380 8114dbeab181de8322016102ef638034 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 1.8E-8 T 28-03-2018 SMD44_RS25380 8114dbeab181de8322016102ef638034 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 1.8E-8 T 28-03-2018 SMD44_RS25380 8114dbeab181de8322016102ef638034 477 Gene3D G3DSA:1.20.1250.20 8 196 3.5E-34 T 28-03-2018 SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 Gene3D G3DSA:1.20.120.530 89 217 1.1E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 SMART SM00895 95 218 4.2E-18 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 5.4E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 SUPERFAMILY SSF48008 94 214 4.45E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 Gene3D G3DSA:1.10.10.10 3 76 1.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 SMART SM00345 15 74 6.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 SUPERFAMILY SSF46785 7 78 3.78E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.2E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.2E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS09355 f70e10dd21f9fe6911bb5dcddee43350 228 Pfam PF07729 FCD domain 96 212 1.2E-23 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS12315 dde44b9b1ecad15190f2d3cec80ffae2 337 Gene3D G3DSA:3.20.20.30 10 336 8.3E-60 T 28-03-2018 SMD44_RS12315 dde44b9b1ecad15190f2d3cec80ffae2 337 Pfam PF00296 Luciferase-like monooxygenase 16 316 1.5E-60 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS12315 dde44b9b1ecad15190f2d3cec80ffae2 337 SUPERFAMILY SSF51679 1 327 2.62E-55 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS12315 dde44b9b1ecad15190f2d3cec80ffae2 337 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 321 9.1E-133 T 28-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 SMART SM00448 3 118 5.9E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 Gene3D G3DSA:1.10.10.10 130 222 2.6E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 Pfam PF00072 Response regulator receiver domain 5 119 1.7E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 SUPERFAMILY SSF46894 147 218 2.82E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 4.7E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 4.7E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 4.7E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 SMART SM00421 155 212 1.7E-28 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 SUPERFAMILY SSF52172 3 137 1.17E-35 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS08200 e1de5617dd2e777a51932ce8263a01bb 223 Gene3D G3DSA:3.40.50.2300 2 129 6.3E-41 T 28-03-2018 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 75 97 4.4E-10 T 28-03-2018 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 4.4E-10 T 28-03-2018 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 337 357 4.4E-10 T 28-03-2018 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 4.4E-10 T 28-03-2018 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 4.4E-10 T 28-03-2018 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 427 5.5E-87 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 SUPERFAMILY SSF103473 4 199 1.22E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 SUPERFAMILY SSF103473 247 471 1.22E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 Gene3D G3DSA:1.20.1250.20 1 199 1.6E-37 T 28-03-2018 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 Pfam PF07690 Major Facilitator Superfamily 17 408 7.7E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS13510 4a5e521b8727e7675eaea038c4f8b6b8 486 Gene3D G3DSA:1.20.1250.20 251 473 4.1E-24 T 28-03-2018 SMD44_RS21670 39377956deec9f93540762445905040f 355 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 271 345 4.4E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS21670 39377956deec9f93540762445905040f 355 Gene3D G3DSA:2.40.30.10 1 101 3.3E-20 T 28-03-2018 SMD44_RS21670 39377956deec9f93540762445905040f 355 Pfam PF00175 Oxidoreductase NAD-binding domain 123 229 1.9E-10 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD44_RS21670 39377956deec9f93540762445905040f 355 Gene3D G3DSA:3.40.50.80 102 241 4.9E-25 T 28-03-2018 SMD44_RS21670 39377956deec9f93540762445905040f 355 Gene3D G3DSA:3.10.20.30 242 355 4.4E-31 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS21670 39377956deec9f93540762445905040f 355 SUPERFAMILY SSF54292 240 349 1.97E-28 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS21670 39377956deec9f93540762445905040f 355 SUPERFAMILY SSF63380 2 114 2.15E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS21670 39377956deec9f93540762445905040f 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 55 62 1.5E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD44_RS21670 39377956deec9f93540762445905040f 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 216 224 1.5E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD44_RS21670 39377956deec9f93540762445905040f 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 120 139 1.5E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD44_RS21670 39377956deec9f93540762445905040f 355 SUPERFAMILY SSF52343 99 246 7.2E-31 T 28-03-2018 SMD44_RS21670 39377956deec9f93540762445905040f 355 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 302 310 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD44_RS21670 39377956deec9f93540762445905040f 355 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 4 354 4.8E-129 T 28-03-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 SMD44_RS21670 39377956deec9f93540762445905040f 355 Pfam PF00970 Oxidoreductase FAD-binding domain 7 110 2.1E-11 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMD44_RS29035 dc350dcd6de39dda64abc86c4f7a5237 318 Gene3D G3DSA:3.40.50.300 45 253 7.2E-38 T 28-03-2018 SMD44_RS29035 dc350dcd6de39dda64abc86c4f7a5237 318 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 15 313 4.3E-105 T 28-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS29035 dc350dcd6de39dda64abc86c4f7a5237 318 Gene3D G3DSA:1.20.5.170 3 42 4.5E-5 T 28-03-2018 SMD44_RS29035 dc350dcd6de39dda64abc86c4f7a5237 318 SMART SM00382 46 296 0.0073 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29035 dc350dcd6de39dda64abc86c4f7a5237 318 Pfam PF03308 ArgK protein 20 281 5.6E-98 T 28-03-2018 SMD44_RS29035 dc350dcd6de39dda64abc86c4f7a5237 318 SUPERFAMILY SSF52540 3 311 2.03E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS33380 2fc3b35ed967123f585c996e715a7fa5 273 ProSitePatterns PS60000 Chitosanases families 46 and 80 active sites signature. 57 95 - T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMD44_RS33380 2fc3b35ed967123f585c996e715a7fa5 273 PIRSF PIRSF036551 3 273 2.1E-116 T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMD44_RS33380 2fc3b35ed967123f585c996e715a7fa5 273 Gene3D G3DSA:3.30.386.10 34 139 6.0E-54 T 28-03-2018 SMD44_RS33380 2fc3b35ed967123f585c996e715a7fa5 273 Gene3D G3DSA:1.20.141.10 140 267 3.5E-58 T 28-03-2018 SMD44_RS33380 2fc3b35ed967123f585c996e715a7fa5 273 Pfam PF01374 Glycosyl hydrolase family 46 51 260 6.2E-104 T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMD44_RS33380 2fc3b35ed967123f585c996e715a7fa5 273 SUPERFAMILY SSF53955 37 272 1.69E-96 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 SMART SM00116 165 213 4.6E-7 T 28-03-2018 IPR000644 CBS domain SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 SMART SM00116 104 152 4.7E-9 T 28-03-2018 IPR000644 CBS domain SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 SMART SM01240 15 487 0.0 T 28-03-2018 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 SUPERFAMILY SSF54631 76 211 5.18E-30 T 28-03-2018 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 500 82.765 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 Pfam PF00571 CBS domain 157 212 1.3E-5 T 28-03-2018 IPR000644 CBS domain SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 Pfam PF00571 CBS domain 101 148 1.2E-8 T 28-03-2018 IPR000644 CBS domain SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 Gene3D G3DSA:3.20.20.70 9 499 7.4E-108 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 468 5.2E-180 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 302 314 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 SUPERFAMILY SSF51412 11 98 5.89E-118 T 28-03-2018 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 SUPERFAMILY SSF51412 224 491 5.89E-118 T 28-03-2018 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 PIRSF PIRSF000130 7 502 1.8E-200 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMD44_RS25815 e998e0a4b65a226ee127e16ba9154a11 502 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 487 5.2E-156 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMD44_RS15210 607a3b069658261aede1c23b48eae09e 271 Pfam PF00005 ABC transporter 37 195 7.8E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS15210 607a3b069658261aede1c23b48eae09e 271 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS15210 607a3b069658261aede1c23b48eae09e 271 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 22 271 1.0E-115 T 28-03-2018 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein SMD44_RS15210 607a3b069658261aede1c23b48eae09e 271 PIRSF PIRSF039085 18 271 2.7E-100 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMD44_RS15210 607a3b069658261aede1c23b48eae09e 271 Gene3D G3DSA:3.40.50.300 18 270 1.3E-74 T 28-03-2018 SMD44_RS15210 607a3b069658261aede1c23b48eae09e 271 SMART SM00382 46 244 4.2E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS15210 607a3b069658261aede1c23b48eae09e 271 SUPERFAMILY SSF52540 21 266 3.24E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10195 7fede686a100c940308bf05146358572 1028 Gene3D G3DSA:3.40.50.300 39 76 0.0061 T 28-03-2018 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 SUPERFAMILY SSF52540 619 913 5.56E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10195 7fede686a100c940308bf05146358572 1028 Gene3D G3DSA:3.40.50.300 617 952 7.5E-55 T 28-03-2018 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 Pfam PF00005 ABC transporter 628 864 1.4E-10 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 Gene3D G3DSA:3.40.50.300 4 38 0.0025 T 28-03-2018 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 Gene3D G3DSA:3.40.50.300 425 616 9.6E-23 T 28-03-2018 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 Gene3D G3DSA:1.10.8.280 289 410 3.9E-35 T 28-03-2018 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.788 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 SUPERFAMILY SSF52540 435 574 2.45E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10195 7fede686a100c940308bf05146358572 1028 SUPERFAMILY SSF52540 10 205 2.45E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10195 7fede686a100c940308bf05146358572 1028 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 Gene3D G3DSA:3.30.190.20 128 251 4.5E-40 T 28-03-2018 SMD44_RS10195 7fede686a100c940308bf05146358572 1028 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SMD44_RS31610 c49f88a9d865000ae84be31ec141246f 394 Gene3D G3DSA:3.40.50.300 3 200 6.3E-37 T 28-03-2018 SMD44_RS31610 c49f88a9d865000ae84be31ec141246f 394 Gene3D G3DSA:3.30.1220.10 234 347 1.4E-21 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS31610 c49f88a9d865000ae84be31ec141246f 394 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 183 5.2E-44 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMD44_RS31610 c49f88a9d865000ae84be31ec141246f 394 SUPERFAMILY SSF90002 256 343 2.48E-16 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS31610 c49f88a9d865000ae84be31ec141246f 394 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 256 345 1.9E-19 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS31610 c49f88a9d865000ae84be31ec141246f 394 SUPERFAMILY SSF52540 5 192 9.15E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31610 c49f88a9d865000ae84be31ec141246f 394 SMART SM00833 255 346 2.1E-10 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 Pfam PF00232 Glycosyl hydrolase family 1 10 446 4.3E-130 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 TIGRFAM TIGR03356 BGL: beta-galactosidase 11 443 3.5E-160 T 28-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 Gene3D G3DSA:3.20.20.80 8 455 4.8E-144 T 28-03-2018 SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 286 300 1.6E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 377 388 1.6E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 422 434 1.6E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 398 415 1.6E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 363 371 1.6E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 15 29 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SMD44_RS13705 824c4f50d53f1da2ee792ff31dbf407c 469 SUPERFAMILY SSF51445 10 448 1.96E-143 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS07940 ad6fa145223a5cb12ebc1918c918bd8e 391 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 44 385 1.1E-97 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin SMD44_RS07940 ad6fa145223a5cb12ebc1918c918bd8e 391 SUPERFAMILY SSF52743 36 329 1.83E-81 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS07940 ad6fa145223a5cb12ebc1918c918bd8e 391 Gene3D G3DSA:3.40.50.200 36 345 7.8E-82 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS07940 ad6fa145223a5cb12ebc1918c918bd8e 391 Pfam PF00082 Subtilase family 54 317 2.5E-46 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS07940 ad6fa145223a5cb12ebc1918c918bd8e 391 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 59 70 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS07940 ad6fa145223a5cb12ebc1918c918bd8e 391 PRINTS PR00723 Subtilisin serine protease family (S8) signature 54 73 1.8E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS07940 ad6fa145223a5cb12ebc1918c918bd8e 391 PRINTS PR00723 Subtilisin serine protease family (S8) signature 266 282 1.8E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS07940 ad6fa145223a5cb12ebc1918c918bd8e 391 PRINTS PR00723 Subtilisin serine protease family (S8) signature 94 107 1.8E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS06100 14f99b047e5c9f64dc5dd153df3f2479 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 244 1.2E-53 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 SMD44_RS06100 14f99b047e5c9f64dc5dd153df3f2479 387 Pfam PF00149 Calcineurin-like phosphoesterase 1 217 1.2E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS06100 14f99b047e5c9f64dc5dd153df3f2479 387 SUPERFAMILY SSF56300 1 306 1.19E-53 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS06100 14f99b047e5c9f64dc5dd153df3f2479 387 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 267 354 6.5E-10 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain SMD44_RS06100 14f99b047e5c9f64dc5dd153df3f2479 387 Gene3D G3DSA:3.60.21.10 69 268 2.9E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS06100 14f99b047e5c9f64dc5dd153df3f2479 387 Gene3D G3DSA:3.60.21.10 1 68 2.0E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS12775 269bc9fc2d7a34cc603b609584a45100 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 80 8.0E-17 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SMD44_RS12775 269bc9fc2d7a34cc603b609584a45100 82 Gene3D G3DSA:1.10.1200.10 2 82 3.4E-23 T 28-03-2018 SMD44_RS12775 269bc9fc2d7a34cc603b609584a45100 82 Pfam PF00550 Phosphopantetheine attachment site 11 77 9.5E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS12775 269bc9fc2d7a34cc603b609584a45100 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 17.261 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SMD44_RS12775 269bc9fc2d7a34cc603b609584a45100 82 SUPERFAMILY SSF47336 2 81 9.29E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 1.7E-74 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 Pfam PF02785 Biotin carboxylase C-terminal domain 333 431 2.0E-34 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 SUPERFAMILY SSF51230 517 588 7.72E-19 T 28-03-2018 IPR011053 Single hybrid motif SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 Gene3D G3DSA:3.30.470.20 209 450 2.0E-91 T 28-03-2018 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 Gene3D G3DSA:3.40.50.20 1 122 5.8E-50 T 28-03-2018 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 Gene3D G3DSA:2.40.50.100 520 590 7.5E-19 T 28-03-2018 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 SMART SM00878 333 447 1.3E-50 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 SUPERFAMILY SSF51246 328 431 4.24E-35 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 SUPERFAMILY SSF52440 2 112 2.3E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 Gene3D G3DSA:3.30.1490.20 123 208 4.6E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 SUPERFAMILY SSF56059 114 321 2.12E-58 T 28-03-2018 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 Pfam PF00364 Biotin-requiring enzyme 522 588 2.2E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 3.8E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS26955 8b2d395304f5384c2e95a8c73a09bb14 590 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 545 562 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS11535 154921a65947ac38fbacc54d6b81f77a 207 Gene3D G3DSA:1.20.120.530 74 204 2.3E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS11535 154921a65947ac38fbacc54d6b81f77a 207 SMART SM00345 13 71 2.4E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS11535 154921a65947ac38fbacc54d6b81f77a 207 Gene3D G3DSA:1.10.10.10 3 73 4.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11535 154921a65947ac38fbacc54d6b81f77a 207 SUPERFAMILY SSF46785 8 99 3.18E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11535 154921a65947ac38fbacc54d6b81f77a 207 SUPERFAMILY SSF48008 78 196 5.49E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS11535 154921a65947ac38fbacc54d6b81f77a 207 SMART SM00895 81 202 6.5E-11 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS11535 154921a65947ac38fbacc54d6b81f77a 207 Pfam PF07729 FCD domain 82 199 6.2E-18 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS11535 154921a65947ac38fbacc54d6b81f77a 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 9.8E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06700 d81449ce6f7583c1619dd5d6a2539652 270 PIRSF PIRSF026671 10 264 2.7E-73 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD44_RS06700 d81449ce6f7583c1619dd5d6a2539652 270 Gene3D G3DSA:3.30.1380.10 36 261 2.2E-71 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS06700 d81449ce6f7583c1619dd5d6a2539652 270 SUPERFAMILY SSF55166 37 260 1.96E-61 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS06700 d81449ce6f7583c1619dd5d6a2539652 270 Pfam PF01427 D-ala-D-ala dipeptidase 192 260 6.4E-14 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD44_RS06700 d81449ce6f7583c1619dd5d6a2539652 270 Pfam PF01427 D-ala-D-ala dipeptidase 39 162 1.9E-15 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD44_RS06700 d81449ce6f7583c1619dd5d6a2539652 270 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 39 259 31.684 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD44_RS15930 32026e5a2d93f4aa2d83b1b02ec12dd4 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SMD44_RS15930 32026e5a2d93f4aa2d83b1b02ec12dd4 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.9E-8 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS15930 32026e5a2d93f4aa2d83b1b02ec12dd4 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.9E-8 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS15930 32026e5a2d93f4aa2d83b1b02ec12dd4 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.9E-8 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS15930 32026e5a2d93f4aa2d83b1b02ec12dd4 93 Gene3D G3DSA:4.10.520.10 1 93 8.1E-30 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD44_RS15930 32026e5a2d93f4aa2d83b1b02ec12dd4 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.2E-28 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS15930 32026e5a2d93f4aa2d83b1b02ec12dd4 93 SMART SM00411 1 91 3.9E-39 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS15930 32026e5a2d93f4aa2d83b1b02ec12dd4 93 SUPERFAMILY SSF47729 1 91 1.21E-26 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD44_RS18370 94db0b2539f778ac3e8f91bc5fab0761 229 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS18370 94db0b2539f778ac3e8f91bc5fab0761 229 SUPERFAMILY SSF52540 4 225 1.08E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18370 94db0b2539f778ac3e8f91bc5fab0761 229 SMART SM00382 32 219 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS18370 94db0b2539f778ac3e8f91bc5fab0761 229 Pfam PF00005 ABC transporter 23 171 1.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS18370 94db0b2539f778ac3e8f91bc5fab0761 229 Gene3D G3DSA:3.40.50.300 1 227 1.3E-62 T 28-03-2018 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 122 138 7.0E-25 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 105 121 7.0E-25 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 42 68 7.0E-25 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 Gene3D G3DSA:3.30.350.10 41 149 2.1E-27 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 Hamap MF_00778 Probable subtilase-type protease inhibitor [sti]. 40 149 29.328 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 Pfam PF00720 Subtilisin inhibitor-like 41 133 2.5E-34 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 SUPERFAMILY SSF55399 40 140 6.02E-34 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 45 137 3.0E-26 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS05435 3aabfb77daecf585da9af210d1f97575 149 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 68 86 - T 28-03-2018 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 Gene3D G3DSA:1.10.3860.10 13 416 1.6E-104 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 1.4E-21 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 PRINTS PR00173 Glutamate-aspartate symporter signature 335 354 1.4E-21 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 PRINTS PR00173 Glutamate-aspartate symporter signature 14 34 1.4E-21 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 PRINTS PR00173 Glutamate-aspartate symporter signature 300 326 1.4E-21 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 PRINTS PR00173 Glutamate-aspartate symporter signature 153 175 1.4E-21 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 SUPERFAMILY SSF118215 16 410 1.44E-106 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 303 326 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site SMD44_RS39430 04b70a0c9b9cc9de40d2ea5549194ab8 454 Pfam PF00375 Sodium:dicarboxylate symporter family 16 409 1.5E-98 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS21175 d69f5748eb130d990a05b55375656d92 102 Gene3D G3DSA:1.10.10.10 4 99 7.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21175 d69f5748eb130d990a05b55375656d92 102 SUPERFAMILY SSF46785 6 96 7.34E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21175 d69f5748eb130d990a05b55375656d92 102 SMART SM00418 9 91 0.003 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS21175 d69f5748eb130d990a05b55375656d92 102 Pfam PF13601 Winged helix DNA-binding domain 18 97 4.4E-18 T 28-03-2018 IPR027395 Winged helix DNA-binding domain SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 6.8E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 SUPERFAMILY SSF53822 63 345 1.85E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 28-03-2018 SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 Gene3D G3DSA:3.40.50.2300 182 347 8.6E-46 T 28-03-2018 SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 SUPERFAMILY SSF47413 4 58 8.34E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 Gene3D G3DSA:3.40.50.2300 61 181 6.1E-27 T 28-03-2018 SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 Gene3D G3DSA:1.10.10.60 2 19 0.0028 T 28-03-2018 SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 Gene3D G3DSA:1.10.260.40 20 60 2.4E-18 T 28-03-2018 SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 SMART SM00354 4 74 3.8E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS11910 429e0e74db0ec56fd7ddbacb21ffa75e 354 Pfam PF13377 Periplasmic binding protein-like domain 182 344 9.7E-36 T 28-03-2018 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 Pfam PF00174 Oxidoreductase molybdopterin binding domain 105 285 7.0E-52 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 343 355 1.5E-25 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 175 190 1.5E-25 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 264 277 1.5E-25 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 93 109 1.5E-25 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 231 247 1.5E-25 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 248 261 1.5E-25 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 388 400 1.5E-25 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 SUPERFAMILY SSF56524 74 299 2.35E-62 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 327 415 2.3E-8 T 28-03-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 Gene3D G3DSA:3.90.420.10 71 301 6.2E-62 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 SUPERFAMILY SSF81296 309 420 7.7E-25 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS33640 01b2baac01d03ffea21b81da17d07c15 421 Gene3D G3DSA:2.60.40.650 308 421 4.5E-24 T 28-03-2018 SMD44_RS18720 dff69ab0ac27f534b24486835bedfc07 229 SMART SM00448 2 116 2.0E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18720 dff69ab0ac27f534b24486835bedfc07 229 Gene3D G3DSA:1.10.10.10 126 228 1.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18720 dff69ab0ac27f534b24486835bedfc07 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 2.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS18720 dff69ab0ac27f534b24486835bedfc07 229 SUPERFAMILY SSF52172 1 152 5.41E-40 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS18720 dff69ab0ac27f534b24486835bedfc07 229 SMART SM00862 150 226 6.0E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS18720 dff69ab0ac27f534b24486835bedfc07 229 Pfam PF00072 Response regulator receiver domain 4 116 1.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18720 dff69ab0ac27f534b24486835bedfc07 229 SUPERFAMILY SSF46894 135 226 4.25E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS18720 dff69ab0ac27f534b24486835bedfc07 229 Gene3D G3DSA:3.40.50.2300 1 125 1.1E-38 T 28-03-2018 SMD44_RS35060 aa50d525b7e91c56074d74fd8c1ea568 685 Gene3D G3DSA:3.40.720.10 127 433 7.6E-27 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD44_RS35060 aa50d525b7e91c56074d74fd8c1ea568 685 Pfam PF04185 Phosphoesterase family 44 428 5.8E-114 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 SMD44_RS35060 aa50d525b7e91c56074d74fd8c1ea568 685 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 683 3.9E-261 T 28-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMD44_RS35060 aa50d525b7e91c56074d74fd8c1ea568 685 Pfam PF05506 Domain of unknown function (DUF756) 589 669 2.5E-17 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMD44_RS35060 aa50d525b7e91c56074d74fd8c1ea568 685 Pfam PF05506 Domain of unknown function (DUF756) 496 582 4.8E-19 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMD44_RS26825 ebdc2230f250c649071b9ef8612395d1 397 Hamap MF_00540 Adenosine deaminase [add]. 27 372 55.906 T 28-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 SMD44_RS26825 ebdc2230f250c649071b9ef8612395d1 397 Gene3D G3DSA:3.20.20.140 22 371 6.5E-81 T 28-03-2018 SMD44_RS26825 ebdc2230f250c649071b9ef8612395d1 397 Pfam PF00962 Adenosine/AMP deaminase 32 369 3.0E-88 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMD44_RS26825 ebdc2230f250c649071b9ef8612395d1 397 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 33 369 1.6E-72 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMD44_RS26825 ebdc2230f250c649071b9ef8612395d1 397 SUPERFAMILY SSF51556 28 365 1.45E-70 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS41945 75b910755d6e03976f07bf5dfa911949 462 Pfam PF07786 Protein of unknown function (DUF1624) 31 236 2.6E-7 T 28-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 SMD44_RS41945 75b910755d6e03976f07bf5dfa911949 462 Pfam PF04235 Protein of unknown function (DUF418) 292 406 2.6E-10 T 28-03-2018 IPR007349 Domain of unknown function DUF418 SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 0.0086 T 28-03-2018 SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 Gene3D G3DSA:3.40.50.720 42 246 5.4E-57 T 28-03-2018 SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 Gene3D G3DSA:3.40.50.720 1 41 1.3E-10 T 28-03-2018 SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 243 2.3E-58 T 28-03-2018 SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 SUPERFAMILY SSF51735 1 244 4.11E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33550 635a7af795abcf995ccbb5d72021afab 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS33020 575ae405edd9e97f1f7978f4f827b907 564 Gene3D G3DSA:1.10.10.60 491 542 2.4E-8 T 28-03-2018 SMD44_RS33020 575ae405edd9e97f1f7978f4f827b907 564 Pfam PF07905 Purine catabolism regulatory protein-like family 6 120 4.0E-27 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain SMD44_RS33020 575ae405edd9e97f1f7978f4f827b907 564 Pfam PF13556 PucR C-terminal helix-turn-helix domain 505 562 1.4E-21 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS01455 26d194212a0869a7d44d9de96ef8c800 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS01455 26d194212a0869a7d44d9de96ef8c800 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS01455 26d194212a0869a7d44d9de96ef8c800 189 Gene3D G3DSA:1.10.10.60 1 60 2.6E-20 T 28-03-2018 SMD44_RS01455 26d194212a0869a7d44d9de96ef8c800 189 SUPERFAMILY SSF46689 6 79 2.89E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01455 26d194212a0869a7d44d9de96ef8c800 189 Gene3D G3DSA:1.10.357.10 61 188 1.5E-17 T 28-03-2018 SMD44_RS01455 26d194212a0869a7d44d9de96ef8c800 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18420 77034190e50b61d1ad40796ca52e1d2e 221 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 192 2.1E-12 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS18420 77034190e50b61d1ad40796ca52e1d2e 221 Gene3D G3DSA:1.10.10.60 1 72 1.6E-16 T 28-03-2018 SMD44_RS18420 77034190e50b61d1ad40796ca52e1d2e 221 SUPERFAMILY SSF48498 82 217 1.45E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS18420 77034190e50b61d1ad40796ca52e1d2e 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 6.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18420 77034190e50b61d1ad40796ca52e1d2e 221 Gene3D G3DSA:1.10.357.10 80 221 3.1E-22 T 28-03-2018 SMD44_RS18420 77034190e50b61d1ad40796ca52e1d2e 221 SUPERFAMILY SSF46689 11 75 9.75E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 Gene3D G3DSA:3.30.565.10 575 706 8.2E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 SUPERFAMILY SSF55781 197 334 4.58E-14 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 SUPERFAMILY SSF81606 364 564 2.09E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 SMART SM00331 349 565 3.9E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 Pfam PF08447 PAS fold 54 140 2.3E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 SMART SM00065 178 331 0.0019 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 SUPERFAMILY SSF55785 40 144 2.44E-12 T 28-03-2018 IPR000014 PAS domain SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 SUPERFAMILY SSF55874 604 697 2.22E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 Gene3D G3DSA:3.30.450.40 156 330 2.2E-21 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 Pfam PF13185 GAF domain 196 321 3.3E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 Gene3D G3DSA:3.30.450.20 36 155 2.1E-12 T 28-03-2018 SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 Pfam PF13581 Histidine kinase-like ATPase domain 583 694 1.7E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 378 565 5.5E-46 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS37260 4bf4d710bb90ca279273ca81aa5f9826 708 Gene3D G3DSA:3.60.40.10 331 568 1.0E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 Gene3D G3DSA:1.10.40.30 384 441 1.7E-25 T 28-03-2018 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 SUPERFAMILY SSF48557 13 462 2.67E-137 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 Pfam PF00206 Lyase 20 309 1.7E-64 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 3.3E-26 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 3.3E-26 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 3.3E-26 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 3.3E-26 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 Pfam PF14698 Argininosuccinate lyase C-terminal 372 439 9.6E-23 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 Gene3D G3DSA:1.20.200.10 115 383 1.3E-91 T 28-03-2018 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 462 40.688 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 2.5E-54 T 28-03-2018 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 2.5E-54 T 28-03-2018 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 2.5E-54 T 28-03-2018 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 2.5E-54 T 28-03-2018 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 2.5E-54 T 28-03-2018 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 2.5E-54 T 28-03-2018 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 464 7.8E-182 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS07745 f9a10c9bc38f6e3c9ff03791a54afb5f 476 Gene3D G3DSA:1.10.275.10 9 114 7.7E-34 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SMD44_RS20350 1d592fdb982ecca12d0552532569decc 276 SUPERFAMILY SSF141673 4 132 1.44E-33 T 28-03-2018 SMD44_RS20350 1d592fdb982ecca12d0552532569decc 276 Pfam PF03473 MOSC domain 141 265 9.1E-29 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 SMD44_RS20350 1d592fdb982ecca12d0552532569decc 276 Pfam PF03476 MOSC N-terminal beta barrel domain 1 117 4.7E-33 T 28-03-2018 IPR005303 MOSC, N-terminal beta barrel SMD44_RS20350 1d592fdb982ecca12d0552532569decc 276 Gene3D G3DSA:2.40.33.20 1 276 2.6E-47 T 28-03-2018 SMD44_RS20350 1d592fdb982ecca12d0552532569decc 276 SUPERFAMILY SSF50800 148 267 1.2E-19 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMD44_RS20350 1d592fdb982ecca12d0552532569decc 276 SUPERFAMILY SSF50800 1 51 1.2E-19 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 452 2.5E-16 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 Gene3D G3DSA:2.40.110.10 160 286 1.7E-24 T 28-03-2018 SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 Gene3D G3DSA:1.20.140.10 287 470 2.1E-33 T 28-03-2018 SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 471 604 6.9E-27 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 5.0E-11 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 1.4E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 SUPERFAMILY SSF56645 38 282 1.44E-41 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 Gene3D G3DSA:1.10.540.10 35 149 3.0E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS21865 48b3ca0ac1b20553f9eb70ced71b0593 608 SUPERFAMILY SSF47203 290 473 1.39E-32 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS22005 bd7dff26e9cdffec9e09ab547ec292a2 213 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 172 1.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS22005 bd7dff26e9cdffec9e09ab547ec292a2 213 Gene3D G3DSA:3.40.50.1000 2 212 2.3E-26 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS22005 bd7dff26e9cdffec9e09ab547ec292a2 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 78 176 4.5E-11 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS22005 bd7dff26e9cdffec9e09ab547ec292a2 213 SUPERFAMILY SSF56784 1 189 1.16E-33 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS36380 ba09c088d67ce27007f776a05872f520 470 Gene3D G3DSA:1.10.260.40 11 82 3.3E-10 T 28-03-2018 SMD44_RS36380 ba09c088d67ce27007f776a05872f520 470 SMART SM00530 19 74 3.6E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS36380 ba09c088d67ce27007f776a05872f520 470 Pfam PF13560 Helix-turn-helix domain 15 77 2.7E-11 T 28-03-2018 SMD44_RS36380 ba09c088d67ce27007f776a05872f520 470 SUPERFAMILY SSF47413 15 68 3.22E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 260 367 6.2E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 SUPERFAMILY SSF55874 204 367 1.45E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 SMART SM00387 259 369 8.9E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 Pfam PF00512 His Kinase A (phospho-acceptor) domain 150 214 8.6E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 Gene3D G3DSA:3.30.565.10 209 369 8.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 SUPERFAMILY SSF47384 137 214 6.08E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 Gene3D G3DSA:1.10.287.130 137 208 3.3E-16 T 28-03-2018 SMD44_RS06190 b45a49d55e277a98a2989ef497ce0f3d 371 SMART SM00388 150 214 7.9E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS38760 670bcf96ae131f210597159254d394f9 144 Gene3D G3DSA:3.10.180.10 1 143 1.8E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS38760 670bcf96ae131f210597159254d394f9 144 SUPERFAMILY SSF54593 4 143 5.32E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS21250 4d75ec47d158485c65b6ceb808dae084 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 3.6E-29 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 Pfam PF00425 chorismate binding enzyme 106 387 3.0E-38 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 SUPERFAMILY SSF56322 39 396 1.19E-55 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 PRINTS PR00097 Anthranilate synthase component II signature 525 536 1.2E-10 T 28-03-2018 SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 PRINTS PR00097 Anthranilate synthase component II signature 611 624 1.2E-10 T 28-03-2018 SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 PRINTS PR00097 Anthranilate synthase component II signature 446 460 1.2E-10 T 28-03-2018 SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 PRINTS PR00096 Glutamine amidotransferase superfamily signature 491 500 7.7E-12 T 28-03-2018 SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 PRINTS PR00096 Glutamine amidotransferase superfamily signature 611 624 7.7E-12 T 28-03-2018 SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 PRINTS PR00096 Glutamine amidotransferase superfamily signature 525 536 7.7E-12 T 28-03-2018 SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 Gene3D G3DSA:3.60.120.10 4 398 3.6E-71 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 Pfam PF00117 Glutamine amidotransferase class-I 448 630 3.7E-27 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 SUPERFAMILY SSF52317 446 634 2.92E-24 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS11215 3a460d833ed2a00e5a5ec4bda78e86b2 650 Gene3D G3DSA:3.40.50.880 445 645 9.4E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS17375 03439703224f11b9adb30ba1aefbad58 415 Gene3D G3DSA:2.60.40.1220 45 149 0.0045 T 28-03-2018 SMD44_RS17375 03439703224f11b9adb30ba1aefbad58 415 Pfam PF13205 Bacterial Ig-like domain 155 251 9.2E-7 T 28-03-2018 IPR032812 SbsA, Ig-like domain SMD44_RS17375 03439703224f11b9adb30ba1aefbad58 415 Gene3D G3DSA:2.40.440.10 249 387 1.1E-27 T 28-03-2018 SMD44_RS17375 03439703224f11b9adb30ba1aefbad58 415 Gene3D G3DSA:1.20.5.510 13 40 0.0023 T 28-03-2018 SMD44_RS17375 03439703224f11b9adb30ba1aefbad58 415 Pfam PF03734 L,D-transpeptidase catalytic domain 257 385 5.5E-15 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD44_RS17375 03439703224f11b9adb30ba1aefbad58 415 SUPERFAMILY SSF141523 259 385 5.75E-24 T 28-03-2018 SMD44_RS35205 baccbfe1c7a0476cb893092d7d039c72 320 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 50 180 7.7E-32 T 28-03-2018 IPR021416 Protein of unknown function DUF3048, N-terminal SMD44_RS35205 baccbfe1c7a0476cb893092d7d039c72 320 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 202 315 6.1E-16 T 28-03-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain SMD44_RS35205 baccbfe1c7a0476cb893092d7d039c72 320 SUPERFAMILY SSF159774 49 318 1.18E-70 T 28-03-2018 IPR023158 YerB-like SMD44_RS35205 baccbfe1c7a0476cb893092d7d039c72 320 Gene3D G3DSA:3.50.90.10 40 320 7.2E-69 T 28-03-2018 IPR023158 YerB-like SMD44_RS10055 828c7a62bfc0dd023b13f2a68ff73338 440 Pfam PF00501 AMP-binding enzyme 50 437 1.7E-43 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS10055 828c7a62bfc0dd023b13f2a68ff73338 440 Gene3D G3DSA:2.30.38.10 365 439 8.5E-15 T 28-03-2018 SMD44_RS10055 828c7a62bfc0dd023b13f2a68ff73338 440 Gene3D G3DSA:3.40.50.980 228 364 1.2E-9 T 28-03-2018 SMD44_RS10055 828c7a62bfc0dd023b13f2a68ff73338 440 Gene3D G3DSA:3.40.50.980 43 227 2.0E-29 T 28-03-2018 SMD44_RS10055 828c7a62bfc0dd023b13f2a68ff73338 440 SUPERFAMILY SSF56801 39 437 8.11E-58 T 28-03-2018 SMD44_RS23080 0024ee5821898835b5a9e43c54bf8e9f 247 PIRSF PIRSF036625 3 244 7.5E-57 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS23080 0024ee5821898835b5a9e43c54bf8e9f 247 SMART SM01012 178 233 6.9E-18 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS23080 0024ee5821898835b5a9e43c54bf8e9f 247 Gene3D G3DSA:3.30.450.40 4 189 7.5E-26 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS23080 0024ee5821898835b5a9e43c54bf8e9f 247 Pfam PF13185 GAF domain 30 164 1.8E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS23080 0024ee5821898835b5a9e43c54bf8e9f 247 Pfam PF03861 ANTAR domain 180 233 1.5E-16 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS23080 0024ee5821898835b5a9e43c54bf8e9f 247 Gene3D G3DSA:1.10.10.10 190 234 6.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23080 0024ee5821898835b5a9e43c54bf8e9f 247 SMART SM00065 26 176 1.3E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS23080 0024ee5821898835b5a9e43c54bf8e9f 247 SUPERFAMILY SSF55781 30 175 3.53E-19 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS26100 f75351e705f852cea69f675217438a3a 420 Pfam PF10901 Protein of unknown function (DUF2690) 315 407 3.7E-22 T 28-03-2018 IPR021224 Protein of unknown function DUF2690 SMD44_RS26100 f75351e705f852cea69f675217438a3a 420 Gene3D G3DSA:1.10.260.40 14 84 7.1E-10 T 28-03-2018 SMD44_RS26100 f75351e705f852cea69f675217438a3a 420 Pfam PF13560 Helix-turn-helix domain 17 74 8.3E-11 T 28-03-2018 SMD44_RS26100 f75351e705f852cea69f675217438a3a 420 SUPERFAMILY SSF47413 16 79 1.9E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS26100 f75351e705f852cea69f675217438a3a 420 SMART SM00530 21 76 1.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 372 381 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 PRINTS PR00359 B-class P450 signature 227 249 6.1E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 PRINTS PR00359 B-class P450 signature 323 350 6.1E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 PRINTS PR00359 B-class P450 signature 176 192 6.1E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 PRINTS PR00359 B-class P450 signature 130 141 6.1E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 PRINTS PR00359 B-class P450 signature 370 379 6.1E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 PRINTS PR00359 B-class P450 signature 193 208 6.1E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 SUPERFAMILY SSF48264 40 433 3.93E-57 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS08050 36239c9f829af1a2bec5d06806a0678c 501 Gene3D G3DSA:1.10.630.10 36 434 8.5E-37 T 28-03-2018 SMD44_RS28845 722ec103158577ad8b005f1df4415923 234 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 37 167 2.9E-16 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS28845 722ec103158577ad8b005f1df4415923 234 SMART SM00226 35 189 7.7E-8 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS28845 722ec103158577ad8b005f1df4415923 234 Gene3D G3DSA:3.40.50.2300 35 231 8.6E-34 T 28-03-2018 SMD44_RS28845 722ec103158577ad8b005f1df4415923 234 SUPERFAMILY SSF52788 196 224 1.57E-22 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS28845 722ec103158577ad8b005f1df4415923 234 SUPERFAMILY SSF52788 35 157 1.57E-22 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS34390 841c7581f1964bf09a789abbf4254062 275 Gene3D G3DSA:3.40.50.150 2 268 8.2E-44 T 28-03-2018 SMD44_RS34390 841c7581f1964bf09a789abbf4254062 275 Pfam PF13847 Methyltransferase domain 44 154 5.8E-28 T 28-03-2018 IPR025714 Methyltransferase domain SMD44_RS34390 841c7581f1964bf09a789abbf4254062 275 SUPERFAMILY SSF53335 14 259 2.17E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 Gene3D G3DSA:2.40.50.140 1 67 5.4E-27 T 28-03-2018 SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 SMART SM00357 3 67 2.8E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 5.3E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 PIRSF PIRSF002599 1 67 4.7E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 SUPERFAMILY SSF50249 1 66 6.86E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 PRINTS PR00050 Cold shock protein signature 25 34 3.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 PRINTS PR00050 Cold shock protein signature 40 58 3.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS22280 678d5aa214651e6b56fda902c3ea0b11 67 PRINTS PR00050 Cold shock protein signature 4 19 3.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS16305 f0ddb401d3c9d1f6d70dce4b84436e46 375 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 9 366 35.407 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMD44_RS16305 f0ddb401d3c9d1f6d70dce4b84436e46 375 Gene3D G3DSA:1.20.120.420 10 148 4.2E-35 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 SMD44_RS16305 f0ddb401d3c9d1f6d70dce4b84436e46 375 Gene3D G3DSA:3.40.50.10470 149 374 7.1E-60 T 28-03-2018 SMD44_RS16305 f0ddb401d3c9d1f6d70dce4b84436e46 375 SUPERFAMILY SSF100950 12 357 3.77E-94 T 28-03-2018 SMD44_RS16305 f0ddb401d3c9d1f6d70dce4b84436e46 375 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 46 356 2.1E-81 T 28-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMD44_RS16305 f0ddb401d3c9d1f6d70dce4b84436e46 375 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 13 355 5.0E-104 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMD44_RS16305 f0ddb401d3c9d1f6d70dce4b84436e46 375 Pfam PF01008 Initiation factor 2 subunit family 58 356 8.4E-60 T 28-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 SMD44_RS04165 7939e45480360c9a208573317ba114a6 238 Pfam PF00753 Metallo-beta-lactamase superfamily 19 216 2.9E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS04165 7939e45480360c9a208573317ba114a6 238 Gene3D G3DSA:3.60.15.10 1 238 1.4E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS04165 7939e45480360c9a208573317ba114a6 238 SMART SM00849 17 216 7.7E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS04165 7939e45480360c9a208573317ba114a6 238 SUPERFAMILY SSF56281 2 230 3.01E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS00965 294ac7af4feb0809a81e76f77845406e 370 Pfam PF13458 Periplasmic binding protein 18 338 6.1E-32 T 28-03-2018 IPR028081 Leucine-binding protein domain SMD44_RS00965 294ac7af4feb0809a81e76f77845406e 370 SUPERFAMILY SSF53822 18 340 1.48E-43 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS00965 294ac7af4feb0809a81e76f77845406e 370 Gene3D G3DSA:3.40.50.2300 2 201 5.7E-29 T 28-03-2018 SMD44_RS00965 294ac7af4feb0809a81e76f77845406e 370 Gene3D G3DSA:3.40.50.2300 202 339 1.7E-5 T 28-03-2018 SMD44_RS29575 d12a3d4516c293139b669b8352fc0d7c 167 Pfam PF13581 Histidine kinase-like ATPase domain 48 157 7.0E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29575 d12a3d4516c293139b669b8352fc0d7c 167 SUPERFAMILY SSF55874 71 158 2.54E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29575 d12a3d4516c293139b669b8352fc0d7c 167 Gene3D G3DSA:3.30.565.10 38 167 7.7E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS12330 32a5d95aa1e9b8a1771e44b8c51fe449 525 Gene3D G3DSA:3.40.50.410 336 523 5.2E-23 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS12330 32a5d95aa1e9b8a1771e44b8c51fe449 525 Gene3D G3DSA:3.40.190.10 129 297 1.8E-7 T 28-03-2018 SMD44_RS12330 32a5d95aa1e9b8a1771e44b8c51fe449 525 SMART SM00327 334 518 1.5E-5 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS12330 32a5d95aa1e9b8a1771e44b8c51fe449 525 SUPERFAMILY SSF53300 337 521 6.38E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS12330 32a5d95aa1e9b8a1771e44b8c51fe449 525 Pfam PF13531 Bacterial extracellular solute-binding protein 36 287 1.2E-20 T 28-03-2018 SMD44_RS12330 32a5d95aa1e9b8a1771e44b8c51fe449 525 SUPERFAMILY SSF53850 35 309 9.42E-16 T 28-03-2018 SMD44_RS12330 32a5d95aa1e9b8a1771e44b8c51fe449 525 Pfam PF00092 von Willebrand factor type A domain 338 513 6.3E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS42495 09ed81edeb3d3435345b19d7b066e5d7 265 Pfam PF00535 Glycosyl transferase family 2 9 103 3.8E-11 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS42495 09ed81edeb3d3435345b19d7b066e5d7 265 Gene3D G3DSA:3.90.550.10 1 252 2.0E-16 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS42495 09ed81edeb3d3435345b19d7b066e5d7 265 SUPERFAMILY SSF53448 9 217 2.16E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 Gene3D G3DSA:4.10.1090.10 326 392 2.3E-15 T 28-03-2018 SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 SUPERFAMILY SSF75005 50 332 6.57E-52 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 Gene3D G3DSA:2.115.10.20 29 325 4.9E-60 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 SUPERFAMILY SSF50370 344 479 2.49E-44 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 Pfam PF04616 Glycosyl hydrolases family 43 57 263 2.9E-25 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 Gene3D G3DSA:2.80.10.50 393 430 4.5E-17 T 28-03-2018 SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 SMART SM00458 345 481 2.5E-18 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 Gene3D G3DSA:2.80.10.50 431 483 5.0E-17 T 28-03-2018 SMD44_RS01540 60be181ff7bd863fe277834c6fe16de4 483 Pfam PF00652 Ricin-type beta-trefoil lectin domain 349 477 4.0E-24 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS14920 4fdca19ee3e6c83f6487da12a3b5bad6 314 Pfam PF01545 Cation efflux family 22 225 5.5E-33 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD44_RS14920 4fdca19ee3e6c83f6487da12a3b5bad6 314 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 313 2.0E-44 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD44_RS14920 4fdca19ee3e6c83f6487da12a3b5bad6 314 Gene3D G3DSA:3.30.70.1350 233 314 2.5E-4 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMD44_RS14920 4fdca19ee3e6c83f6487da12a3b5bad6 314 SUPERFAMILY SSF161111 19 232 2.88E-37 T 28-03-2018 SMD44_RS14920 4fdca19ee3e6c83f6487da12a3b5bad6 314 Gene3D G3DSA:1.20.1510.10 19 231 3.4E-31 T 28-03-2018 SMD44_RS14920 4fdca19ee3e6c83f6487da12a3b5bad6 314 SUPERFAMILY SSF160240 236 313 2.88E-5 T 28-03-2018 SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 PRINTS PR01438 Universal stress protein signature 2 20 6.4E-12 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 PRINTS PR01438 Universal stress protein signature 96 108 6.4E-12 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 PRINTS PR01438 Universal stress protein signature 114 136 6.4E-12 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 SUPERFAMILY SSF52402 4 141 3.35E-26 T 28-03-2018 SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 SUPERFAMILY SSF52402 163 294 1.76E-18 T 28-03-2018 SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 Gene3D G3DSA:3.40.50.620 149 295 7.0E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 Gene3D G3DSA:3.40.50.620 1 148 4.9E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 Pfam PF00582 Universal stress protein family 1 136 6.5E-22 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS39255 40e15032b0f6a2d49e0911cda9b856c2 295 Pfam PF00582 Universal stress protein family 154 293 1.8E-13 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 212 1.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 196 1.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 212 224 1.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 ProSitePatterns PS00622 LuxR-type HTH domain signature. 196 223 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 Pfam PF00196 Bacterial regulatory proteins, luxR family 181 236 3.4E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 SMART SM00421 179 236 6.3E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 SMART SM00448 11 153 1.8E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 Pfam PF00072 Response regulator receiver domain 14 81 6.8E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 Pfam PF00072 Response regulator receiver domain 114 153 4.7E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 SUPERFAMILY SSF46894 170 242 1.43E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 Gene3D G3DSA:3.40.50.2300 10 164 4.3E-32 T 28-03-2018 SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 SUPERFAMILY SSF52172 10 84 9.4E-28 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 SUPERFAMILY SSF52172 112 186 9.4E-28 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS18905 708bf7d85b50a3f8c872789f8f0c62c3 243 Gene3D G3DSA:1.10.10.10 165 243 5.7E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 SUPERFAMILY SSF81923 3 144 3.43E-33 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 SUPERFAMILY SSF52540 167 445 1.4E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Gene3D G3DSA:1.10.8.60 348 491 1.6E-39 T 28-03-2018 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 329 1.6E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 712 1.5E-54 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 SMART SM00382 541 720 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 SMART SM00382 204 348 5.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Gene3D G3DSA:1.10.8.60 719 821 3.5E-24 T 28-03-2018 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 798 3.9E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Pfam PF02151 UvrB/uvrC motif 421 453 6.0E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Gene3D G3DSA:3.40.50.300 197 346 2.3E-18 T 28-03-2018 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Gene3D G3DSA:3.40.50.300 496 718 2.1E-57 T 28-03-2018 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.2E-19 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.6E-17 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 SMART SM01086 719 810 6.5E-37 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Gene3D G3DSA:1.10.1780.10 79 196 3.1E-30 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 SUPERFAMILY SSF52540 490 801 2.8E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 Gene3D G3DSA:1.10.1780.10 1 78 1.3E-29 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 2.4E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 2.4E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 2.4E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SMD44_RS23885 aa0f2fb6c7cbf1d3a6a9f706ca33b3db 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 2.4E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 Pfam PF07732 Multicopper oxidase 286 402 6.5E-36 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 SUPERFAMILY SSF49503 264 402 1.46E-36 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 Gene3D G3DSA:2.60.40.420 251 403 5.3E-37 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 ProSitePatterns PS00080 Multicopper oxidases signature 2. 664 675 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 Gene3D G3DSA:2.60.40.420 538 690 5.1E-35 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 Pfam PF07731 Multicopper oxidase 578 681 4.8E-28 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 Gene3D G3DSA:2.60.40.420 423 518 2.5E-12 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 SUPERFAMILY SSF49503 570 678 2.21E-34 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS33250 72601c681728facf7ac686b45b93f448 699 SUPERFAMILY SSF49503 407 504 1.51E-8 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 266 339 1.5E-28 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 265 340 1.0E-23 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 SMART SM00382 64 195 1.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 Gene3D G3DSA:1.10.10.10 270 340 1.5E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 Gene3D G3DSA:1.10.8.60 197 267 6.6E-32 T 28-03-2018 SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 37 339 2.3E-134 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 SUPERFAMILY SSF46785 270 343 2.65E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 Gene3D G3DSA:3.40.50.300 31 194 5.7E-26 T 28-03-2018 SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 SUPERFAMILY SSF52540 33 264 1.59E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 357 159.966 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMD44_RS07445 37e8ed0f8fd1665f7b917867014f55b0 357 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 17 248 8.2E-110 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PIRSF PIRSF000532 1 342 2.1E-125 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 Gene3D G3DSA:3.40.50.450 205 323 2.5E-15 T 28-03-2018 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 2.1E-69 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 Pfam PF00365 Phosphofructokinase 2 297 2.5E-104 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 SUPERFAMILY SSF53784 1 332 1.83E-122 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 322 2.6E-155 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 Gene3D G3DSA:3.40.50.450 1 204 4.1E-77 T 28-03-2018 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 342 44.012 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS11225 0ded8f385bafaf2c4cabb243e7c155d7 342 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 Pfam PF00005 ABC transporter 279 433 3.5E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 Pfam PF00005 ABC transporter 17 173 9.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 SUPERFAMILY SSF52540 266 495 2.62E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 Gene3D G3DSA:3.40.50.300 1 239 4.7E-51 T 28-03-2018 SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 SUPERFAMILY SSF52540 2 231 5.63E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 SMART SM00382 26 244 5.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 SMART SM00382 288 482 5.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS37050 ba40e9974559419f4a82407a1b5a7fd9 519 Gene3D G3DSA:3.40.50.300 249 512 6.9E-47 T 28-03-2018 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 422 1.9E-118 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 Hamap MF_00318 Enolase [eno]. 2 411 43.129 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 Pfam PF03952 Enolase, N-terminal domain 4 134 7.1E-58 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 ProSitePatterns PS00164 Enolase signature. 334 347 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 1.4E-196 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 Gene3D G3DSA:3.20.20.120 128 424 7.0E-98 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 Gene3D G3DSA:3.30.390.10 3 127 3.3E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 SMART SM01192 139 425 5.9E-200 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 PRINTS PR00148 Enolase signature 363 380 2.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 PRINTS PR00148 Enolase signature 37 51 2.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 PRINTS PR00148 Enolase signature 107 123 2.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 PRINTS PR00148 Enolase signature 161 174 2.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 PRINTS PR00148 Enolase signature 311 322 2.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 PRINTS PR00148 Enolase signature 334 348 2.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 PIRSF PIRSF001400 1 424 7.0E-179 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 SUPERFAMILY SSF54826 4 136 2.47E-53 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 SMART SM01193 4 134 6.0E-88 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS01555 4d8be369cfa57d02baef4736892cb546 427 SUPERFAMILY SSF51604 139 422 2.49E-118 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 ProSitePatterns PS00177 DNA topoisomerase II signature. 484 492 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 326 339 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 566 583 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 548 564 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 52 67 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 482 496 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 586 598 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 87 100 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 130 144 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR00418 DNA topoisomerase II family signature 637 653 3.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 SUPERFAMILY SSF55874 23 241 2.23E-58 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 Pfam PF01751 Toprim domain 481 588 3.9E-15 T 28-03-2018 IPR006171 TOPRIM domain SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 259 281 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 658 670 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 23 33 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 214 229 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 674 690 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 436 456 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 532 541 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 229 242 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 PRINTS PR01159 DNA gyrase subunit B signature 370 386 1.4E-34 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 Gene3D G3DSA:3.30.565.10 35 253 2.0E-65 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 48 153 1.0E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 Gene3D G3DSA:3.40.50.670 462 703 6.1E-82 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 SMART SM00433 52 698 2.6E-282 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 SUPERFAMILY SSF54211 260 452 5.88E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 SMART SM00387 48 208 1.7E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 636 693 7.2E-25 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 Gene3D G3DSA:3.30.230.10 259 454 4.9E-49 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 Pfam PF00204 DNA gyrase B 260 452 5.9E-55 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31545 1c94fdab5d95059b22de875da483a32b 707 SUPERFAMILY SSF56719 456 697 1.07E-74 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMD44_RS43805 0584d9af483089d635fe4e96320b08c8 254 Gene3D G3DSA:3.40.50.300 19 155 1.2E-10 T 28-03-2018 SMD44_RS43805 0584d9af483089d635fe4e96320b08c8 254 Pfam PF13401 AAA domain 32 159 2.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS43805 0584d9af483089d635fe4e96320b08c8 254 SUPERFAMILY SSF52540 36 238 5.5E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 Pfam PF04542 Sigma-70 region 2 10 74 6.9E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 9 292 2.4E-103 T 28-03-2018 IPR014303 RNA polymerase sigma-70, ECF type SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 Gene3D G3DSA:1.10.1740.10 3 77 2.5E-16 T 28-03-2018 SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 Gene3D G3DSA:3.10.450.50 155 295 5.3E-22 T 28-03-2018 SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 SUPERFAMILY SSF88946 8 86 1.69E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 164 5.2E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 SUPERFAMILY SSF88659 105 163 2.8E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 Pfam PF08281 Sigma-70, region 4 112 162 7.0E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 Gene3D G3DSA:1.10.10.10 93 154 8.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06040 4ad93d37a7ed75b0fedbb7ca825aad26 340 SUPERFAMILY SSF54427 173 291 1.32E-12 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Gene3D G3DSA:1.10.10.60 81 136 0.026 T 28-03-2018 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Pfam PF06029 AlkA N-terminal domain 201 329 2.6E-28 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 SUPERFAMILY SSF48150 319 452 6.67E-11 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 SUPERFAMILY SSF46689 136 183 3.14E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 SMART SM01009 200 329 8.8E-38 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Gene3D G3DSA:3.30.310.20 200 314 2.2E-33 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 SUPERFAMILY SSF57884 3 83 1.18E-31 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 SMART SM00342 99 182 5.2E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 136 178 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Pfam PF02805 Metal binding domain of Ada 7 70 1.9E-29 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Gene3D G3DSA:1.10.340.30 315 375 0.02 T 28-03-2018 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Gene3D G3DSA:1.10.340.30 376 441 9.2E-5 T 28-03-2018 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 SUPERFAMILY SSF55945 201 310 1.73E-15 T 28-03-2018 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Pfam PF12833 Helix-turn-helix domain 105 183 6.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Gene3D G3DSA:1.10.10.60 137 188 1.5E-9 T 28-03-2018 SMD44_RS32935 8b3fc6affe453c436eebe4910c9f5766 465 Gene3D G3DSA:3.40.10.10 1 72 6.1E-26 T 28-03-2018 IPR035451 Ada-like domain SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 Gene3D G3DSA:3.40.190.80 155 266 3.3E-23 T 28-03-2018 SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 262 1.5E-91 T 28-03-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 Gene3D G3DSA:3.30.540.10 1 154 8.4E-44 T 28-03-2018 SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 1.7E-14 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 1.7E-14 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.7E-14 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 1.7E-14 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 Pfam PF00459 Inositol monophosphatase family 10 263 2.7E-45 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS28225 15cc90ff1c62074a059e4d0996403def 266 SUPERFAMILY SSF56655 3 264 1.2E-74 T 28-03-2018 SMD44_RS32000 9066c800ed6b17903ee1c2decb181cb7 131 SUPERFAMILY SSF50331 12 128 3.64E-16 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMD44_RS32000 9066c800ed6b17903ee1c2decb181cb7 131 Pfam PF12728 Helix-turn-helix domain 4 53 1.4E-6 T 28-03-2018 SMD44_RS32000 9066c800ed6b17903ee1c2decb181cb7 131 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 39 1.6E-7 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD44_RS32000 9066c800ed6b17903ee1c2decb181cb7 131 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 66 129 3.3E-16 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 SMD44_RS32000 9066c800ed6b17903ee1c2decb181cb7 131 Gene3D G3DSA:2.40.50.100 78 129 7.4E-17 T 28-03-2018 SMD44_RS32000 9066c800ed6b17903ee1c2decb181cb7 131 Gene3D G3DSA:1.10.1660.10 1 77 1.1E-7 T 28-03-2018 SMD44_RS32000 9066c800ed6b17903ee1c2decb181cb7 131 Pfam PF03459 TOBE domain 66 128 1.6E-14 T 28-03-2018 IPR005116 Transport-associated OB, type 1 SMD44_RS15700 dd352a9f2da36475006066ce76a30c02 434 SUPERFAMILY SSF51690 137 428 1.62E-78 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMD44_RS15700 dd352a9f2da36475006066ce76a30c02 434 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 154 321 1.8E-5 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMD44_RS15700 dd352a9f2da36475006066ce76a30c02 434 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 7 376 1.6E-127 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 SMD44_RS15700 dd352a9f2da36475006066ce76a30c02 434 SUPERFAMILY SSF54675 4 135 3.09E-44 T 28-03-2018 SMD44_RS15700 dd352a9f2da36475006066ce76a30c02 434 Gene3D G3DSA:3.20.140.10 2 374 1.6E-99 T 28-03-2018 SMD44_RS15700 dd352a9f2da36475006066ce76a30c02 434 PIRSF PIRSF000484 3 432 3.1E-104 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMD44_RS30910 a74c366d2e4b1a4bda18ce8a217c3149 350 Pfam PF00005 ABC transporter 37 191 2.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS30910 a74c366d2e4b1a4bda18ce8a217c3149 350 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 309 1.7E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS30910 a74c366d2e4b1a4bda18ce8a217c3149 350 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS30910 a74c366d2e4b1a4bda18ce8a217c3149 350 SMART SM00382 45 249 3.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS30910 a74c366d2e4b1a4bda18ce8a217c3149 350 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 328 9.6E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS30910 a74c366d2e4b1a4bda18ce8a217c3149 350 SUPERFAMILY SSF52540 19 262 3.77E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30910 a74c366d2e4b1a4bda18ce8a217c3149 350 Gene3D G3DSA:3.40.50.300 16 344 1.6E-72 T 28-03-2018 SMD44_RS04885 b8f7129e8a02ac3963ba863e4afa4e6f 356 Gene3D G3DSA:3.90.1150.10 261 356 1.9E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS04885 b8f7129e8a02ac3963ba863e4afa4e6f 356 Pfam PF01212 Beta-eliminating lyase 19 304 1.1E-56 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 SMD44_RS04885 b8f7129e8a02ac3963ba863e4afa4e6f 356 SUPERFAMILY SSF53383 17 353 7.98E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS04885 b8f7129e8a02ac3963ba863e4afa4e6f 356 Gene3D G3DSA:3.40.640.10 28 260 1.4E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS29675 0db0f86c330fd9fd734cacd2365a9031 273 Pfam PF14581 SseB protein C-terminal domain 162 271 1.6E-25 T 28-03-2018 IPR027945 SseB protein, C-terminal SMD44_RS29675 0db0f86c330fd9fd734cacd2365a9031 273 Pfam PF07179 SseB protein N-terminal domain 36 149 2.4E-17 T 28-03-2018 IPR009839 SseB protein N-terminal domain SMD44_RS33390 d5e4b57a8c72127c01c3ae8d71e476eb 745 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 53 131 2.4E-19 T 28-03-2018 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMD44_RS33390 d5e4b57a8c72127c01c3ae8d71e476eb 745 Gene3D G3DSA:1.20.120.670 468 744 2.1E-75 T 28-03-2018 SMD44_RS33390 d5e4b57a8c72127c01c3ae8d71e476eb 745 Gene3D G3DSA:3.20.20.80 141 467 5.8E-102 T 28-03-2018 SMD44_RS33390 d5e4b57a8c72127c01c3ae8d71e476eb 745 Gene3D G3DSA:3.30.379.10 42 140 7.5E-24 T 28-03-2018 SMD44_RS33390 d5e4b57a8c72127c01c3ae8d71e476eb 745 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 145 465 4.6E-97 T 28-03-2018 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMD44_RS33390 d5e4b57a8c72127c01c3ae8d71e476eb 745 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 474 737 3.5E-67 T 28-03-2018 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMD44_RS11030 9a16d4b7809336589c36dfbdf0e81444 364 SUPERFAMILY SSF53756 2 358 2.92E-98 T 28-03-2018 SMD44_RS11030 9a16d4b7809336589c36dfbdf0e81444 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 3.0E-43 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS11030 9a16d4b7809336589c36dfbdf0e81444 364 Gene3D G3DSA:3.40.50.2000 1 171 2.1E-36 T 28-03-2018 SMD44_RS11030 9a16d4b7809336589c36dfbdf0e81444 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 347 6.1E-40 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SMD44_RS11030 9a16d4b7809336589c36dfbdf0e81444 364 Gene3D G3DSA:3.40.50.2000 172 352 5.3E-36 T 28-03-2018 SMD44_RS11030 9a16d4b7809336589c36dfbdf0e81444 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 358 31.579 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS11030 9a16d4b7809336589c36dfbdf0e81444 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 352 4.7E-86 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS11620 cd0bc668e47eca1d301a29349fd22af0 235 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 1 229 1.0E-85 T 28-03-2018 SMD44_RS11620 cd0bc668e47eca1d301a29349fd22af0 235 Pfam PF13829 Domain of unknown function (DUF4191) 13 229 2.5E-82 T 28-03-2018 IPR025445 Protein of unknown function DUF4191 SMD44_RS23195 63ade847e623cd048fbd8e8b4347c878 261 Pfam PF00293 NUDIX domain 82 201 6.7E-10 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS23195 63ade847e623cd048fbd8e8b4347c878 261 Gene3D G3DSA:3.90.79.10 4 244 1.2E-31 T 28-03-2018 SMD44_RS23195 63ade847e623cd048fbd8e8b4347c878 261 SUPERFAMILY SSF55811 71 240 1.6E-24 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS33760 3191812be483ea171a70401eefb22ed2 447 SUPERFAMILY SSF111331 158 445 1.05E-43 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD44_RS33760 3191812be483ea171a70401eefb22ed2 447 Pfam PF00781 Diacylglycerol kinase catalytic domain 159 275 5.6E-14 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD44_RS33760 3191812be483ea171a70401eefb22ed2 447 Gene3D G3DSA:1.20.144.10 10 145 7.9E-7 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS33760 3191812be483ea171a70401eefb22ed2 447 Gene3D G3DSA:3.40.50.10330 154 285 8.8E-16 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMD44_RS33760 3191812be483ea171a70401eefb22ed2 447 SUPERFAMILY SSF48317 21 139 2.75E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS33760 3191812be483ea171a70401eefb22ed2 447 SMART SM00046 158 276 4.0E-4 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD44_RS32505 a5489515ce285c74bba32b712aa2e23d 156 SUPERFAMILY SSF52402 5 153 1.12E-21 T 28-03-2018 SMD44_RS32505 a5489515ce285c74bba32b712aa2e23d 156 Gene3D G3DSA:3.40.50.620 17 154 9.5E-6 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS07810 b6ca840c85614eb7be233f4b7e867077 739 SUPERFAMILY SSF53659 4 738 0.0 T 28-03-2018 SMD44_RS07810 b6ca840c85614eb7be233f4b7e867077 739 PIRSF PIRSF009407 1 739 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMD44_RS07810 b6ca840c85614eb7be233f4b7e867077 739 Gene3D G3DSA:3.40.718.10 435 711 1.9E-40 T 28-03-2018 SMD44_RS07810 b6ca840c85614eb7be233f4b7e867077 739 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 738 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMD44_RS07810 b6ca840c85614eb7be233f4b7e867077 739 Gene3D G3DSA:3.40.718.10 7 363 2.0E-44 T 28-03-2018 SMD44_RS07810 b6ca840c85614eb7be233f4b7e867077 739 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 735 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMD44_RS04155 a0220237e54e3c328357dd4c87554772 420 SMART SM00387 320 416 3.5E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04155 a0220237e54e3c328357dd4c87554772 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 413 6.6E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS04155 a0220237e54e3c328357dd4c87554772 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 394 6.6E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS04155 a0220237e54e3c328357dd4c87554772 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 6.6E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS04155 a0220237e54e3c328357dd4c87554772 420 Gene3D G3DSA:3.30.565.10 280 418 1.6E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04155 a0220237e54e3c328357dd4c87554772 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 415 1.7E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04155 a0220237e54e3c328357dd4c87554772 420 Pfam PF07730 Histidine kinase 217 282 3.5E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS04155 a0220237e54e3c328357dd4c87554772 420 SUPERFAMILY SSF55874 308 414 1.15E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS02600 3db9c60865d31afd2eb789f3d6bca518 292 SUPERFAMILY SSF53474 7 280 1.06E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02600 3db9c60865d31afd2eb789f3d6bca518 292 Gene3D G3DSA:3.40.50.1820 3 285 8.6E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02600 3db9c60865d31afd2eb789f3d6bca518 292 Pfam PF12697 Alpha/beta hydrolase family 9 275 6.1E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS01115 68a1b34063397e3d962f0b9e54a6207f 544 Gene3D G3DSA:1.10.510.10 74 277 3.0E-44 T 28-03-2018 SMD44_RS01115 68a1b34063397e3d962f0b9e54a6207f 544 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS01115 68a1b34063397e3d962f0b9e54a6207f 544 Gene3D G3DSA:3.30.200.20 13 73 2.1E-10 T 28-03-2018 SMD44_RS01115 68a1b34063397e3d962f0b9e54a6207f 544 Pfam PF00069 Protein kinase domain 23 268 1.1E-35 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS01115 68a1b34063397e3d962f0b9e54a6207f 544 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 28 50 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS01115 68a1b34063397e3d962f0b9e54a6207f 544 SUPERFAMILY SSF56112 19 271 1.35E-61 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS01115 68a1b34063397e3d962f0b9e54a6207f 544 SMART SM00220 22 270 3.2E-37 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 SUPERFAMILY SSF53244 317 458 2.2E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 Gene3D G3DSA:3.90.190.20 314 474 2.5E-48 T 28-03-2018 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 SUPERFAMILY SSF53623 102 310 6.54E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 Gene3D G3DSA:3.40.1190.10 92 310 3.1E-59 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 402 6.8E-19 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 462 32.362 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 Gene3D G3DSA:3.40.1390.10 2 91 1.7E-28 T 28-03-2018 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 Pfam PF01225 Mur ligase family, catalytic domain 31 95 5.1E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 Pfam PF08245 Mur ligase middle domain 108 294 6.7E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 SUPERFAMILY SSF63418 4 97 6.28E-21 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD44_RS11050 82f1b68cd37c1780e4ab2e76ddfb40b0 476 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 458 4.4E-130 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS13725 12b2e21a35a0c195520ad0cfcb762c57 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 46 70 2.9E-5 T 28-03-2018 SMD44_RS13725 12b2e21a35a0c195520ad0cfcb762c57 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 168 192 2.9E-5 T 28-03-2018 SMD44_RS13725 12b2e21a35a0c195520ad0cfcb762c57 486 Gene3D G3DSA:1.20.1250.20 34 228 7.3E-36 T 28-03-2018 SMD44_RS13725 12b2e21a35a0c195520ad0cfcb762c57 486 Gene3D G3DSA:1.20.1250.20 287 486 2.0E-23 T 28-03-2018 SMD44_RS13725 12b2e21a35a0c195520ad0cfcb762c57 486 SUPERFAMILY SSF103473 278 483 5.62E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS13725 12b2e21a35a0c195520ad0cfcb762c57 486 SUPERFAMILY SSF103473 30 230 5.62E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS13725 12b2e21a35a0c195520ad0cfcb762c57 486 Pfam PF07690 Major Facilitator Superfamily 48 440 2.6E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS06430 13ea1deffa3766f08adec777c336e0d8 412 Gene3D G3DSA:3.50.50.60 6 373 2.5E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06430 13ea1deffa3766f08adec777c336e0d8 412 Pfam PF01494 FAD binding domain 11 345 2.8E-23 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS06430 13ea1deffa3766f08adec777c336e0d8 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 7.8E-20 T 28-03-2018 SMD44_RS06430 13ea1deffa3766f08adec777c336e0d8 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 7.8E-20 T 28-03-2018 SMD44_RS06430 13ea1deffa3766f08adec777c336e0d8 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 7.8E-20 T 28-03-2018 SMD44_RS06430 13ea1deffa3766f08adec777c336e0d8 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 7.8E-20 T 28-03-2018 SMD44_RS06430 13ea1deffa3766f08adec777c336e0d8 412 SUPERFAMILY SSF51905 10 176 8.15E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS06430 13ea1deffa3766f08adec777c336e0d8 412 SUPERFAMILY SSF51905 270 376 8.15E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS01460 bf66992254d898d0fd0919a89884a71e 297 SMART SM00829 10 295 2.9E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS01460 bf66992254d898d0fd0919a89884a71e 297 SUPERFAMILY SSF50129 1 147 4.26E-29 T 28-03-2018 IPR011032 GroES-like SMD44_RS01460 bf66992254d898d0fd0919a89884a71e 297 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 4.6E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS01460 bf66992254d898d0fd0919a89884a71e 297 Gene3D G3DSA:3.90.180.10 143 296 1.1E-13 T 28-03-2018 SMD44_RS01460 bf66992254d898d0fd0919a89884a71e 297 Gene3D G3DSA:3.90.180.10 1 142 4.3E-39 T 28-03-2018 SMD44_RS01460 bf66992254d898d0fd0919a89884a71e 297 SUPERFAMILY SSF51735 111 293 9.56E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01460 bf66992254d898d0fd0919a89884a71e 297 Pfam PF13602 Zinc-binding dehydrogenase 195 295 4.4E-12 T 28-03-2018 SMD44_RS01460 bf66992254d898d0fd0919a89884a71e 297 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS20195 233d9e31decefb6480d7b05509bd8770 211 Gene3D G3DSA:3.40.50.2020 1 208 2.8E-65 T 28-03-2018 SMD44_RS20195 233d9e31decefb6480d7b05509bd8770 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 210 43.952 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SMD44_RS20195 233d9e31decefb6480d7b05509bd8770 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 1.1E-76 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SMD44_RS20195 233d9e31decefb6480d7b05509bd8770 211 Pfam PF14681 Uracil phosphoribosyltransferase 5 209 1.1E-64 T 28-03-2018 SMD44_RS20195 233d9e31decefb6480d7b05509bd8770 211 SUPERFAMILY SSF53271 3 208 9.05E-65 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS09500 01c72aa59143e63b5d0054843751354a 656 Pfam PF00723 Glycosyl hydrolases family 15 221 644 1.7E-61 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMD44_RS09500 01c72aa59143e63b5d0054843751354a 656 SUPERFAMILY SSF48208 196 514 1.51E-94 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS09500 01c72aa59143e63b5d0054843751354a 656 SUPERFAMILY SSF48208 573 649 1.51E-94 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS09500 01c72aa59143e63b5d0054843751354a 656 Gene3D G3DSA:1.50.10.10 192 606 4.2E-96 T 28-03-2018 SMD44_RS39650 fae248ae8e60c7a58038bafc549e9d74 83 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 13.945 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SMD44_RS39650 fae248ae8e60c7a58038bafc549e9d74 83 SUPERFAMILY SSF47336 1 79 3.4E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS39650 fae248ae8e60c7a58038bafc549e9d74 83 ProSitePatterns PS00012 Phosphopantetheine attachment site. 34 49 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS39650 fae248ae8e60c7a58038bafc549e9d74 83 Pfam PF00550 Phosphopantetheine attachment site 9 75 5.6E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS39650 fae248ae8e60c7a58038bafc549e9d74 83 SMART SM00823 Phosphopantetheine attachment site 7 79 8.2E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS39650 fae248ae8e60c7a58038bafc549e9d74 83 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 37 77 7.0E-5 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SMD44_RS39650 fae248ae8e60c7a58038bafc549e9d74 83 Gene3D G3DSA:1.10.1200.10 1 82 1.4E-21 T 28-03-2018 SMD44_RS40320 1afacdf7fcd747a92f80ec1e8dda4540 342 SUPERFAMILY SSF160240 233 304 1.83E-7 T 28-03-2018 SMD44_RS40320 1afacdf7fcd747a92f80ec1e8dda4540 342 Gene3D G3DSA:3.30.70.1350 228 306 3.4E-9 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMD44_RS40320 1afacdf7fcd747a92f80ec1e8dda4540 342 Pfam PF01545 Cation efflux family 36 225 3.4E-40 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD44_RS40320 1afacdf7fcd747a92f80ec1e8dda4540 342 SUPERFAMILY SSF161111 30 226 1.57E-47 T 28-03-2018 SMD44_RS40320 1afacdf7fcd747a92f80ec1e8dda4540 342 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 31 305 1.9E-70 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD44_RS40320 1afacdf7fcd747a92f80ec1e8dda4540 342 Gene3D G3DSA:1.20.1510.10 30 225 6.7E-44 T 28-03-2018 SMD44_RS36125 c6d737f60b4805793b804fa053b241ef 384 Pfam PF01960 ArgJ family 11 384 6.5E-124 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS36125 c6d737f60b4805793b804fa053b241ef 384 Gene3D G3DSA:3.60.70.12 1 260 4.9E-94 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS36125 c6d737f60b4805793b804fa053b241ef 384 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 384 131.506 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS36125 c6d737f60b4805793b804fa053b241ef 384 SUPERFAMILY SSF56266 7 380 9.02E-124 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS36125 c6d737f60b4805793b804fa053b241ef 384 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 18 382 5.0E-174 T 28-03-2018 SMD44_RS36125 c6d737f60b4805793b804fa053b241ef 384 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 383 3.6E-101 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS15850 2a6e7f3f6b62003c917599dd560f5a36 139 Gene3D G3DSA:3.30.565.10 10 138 6.6E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15850 2a6e7f3f6b62003c917599dd560f5a36 139 SUPERFAMILY SSF55874 43 135 1.19E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15850 2a6e7f3f6b62003c917599dd560f5a36 139 Pfam PF13581 Histidine kinase-like ATPase domain 20 120 3.9E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 Pfam PF00561 alpha/beta hydrolase fold 32 312 1.2E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 SUPERFAMILY SSF53474 8 190 1.32E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 SUPERFAMILY SSF53474 220 327 1.32E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 PRINTS PR00412 Epoxide hydrolase signature 104 117 1.0E-27 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 PRINTS PR00412 Epoxide hydrolase signature 302 324 1.0E-27 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 PRINTS PR00412 Epoxide hydrolase signature 58 73 1.0E-27 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 PRINTS PR00412 Epoxide hydrolase signature 266 282 1.0E-27 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 PRINTS PR00412 Epoxide hydrolase signature 38 56 1.0E-27 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 PRINTS PR00412 Epoxide hydrolase signature 118 131 1.0E-27 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS23405 40f17a63982b7ce7dcab34110de6f094 329 Gene3D G3DSA:3.40.50.1820 8 329 5.6E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 Gene3D G3DSA:1.10.630.10 5 396 2.2E-77 T 28-03-2018 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 87 98 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 287 314 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 133 149 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 345 356 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 315 330 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 150 165 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 269 280 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 336 345 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 PRINTS PR00359 B-class P450 signature 188 210 8.7E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 Pfam PF00067 Cytochrome P450 197 366 5.3E-19 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS10355 8cd010a7b94128bae14399ea31c9e14c 396 SUPERFAMILY SSF48264 12 396 9.56E-100 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 Gene3D G3DSA:3.50.50.60 272 359 1.0E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 7.7E-7 T 28-03-2018 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 7.7E-7 T 28-03-2018 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 7.7E-7 T 28-03-2018 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 Gene3D G3DSA:3.50.50.60 2 99 2.8E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 SUPERFAMILY SSF51905 225 342 2.19E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 SUPERFAMILY SSF51905 10 136 2.19E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 SUPERFAMILY SSF51905 165 183 2.19E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 Gene3D G3DSA:3.50.50.60 100 254 1.8E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 2.0E-11 T 28-03-2018 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.0E-11 T 28-03-2018 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.0E-11 T 28-03-2018 SMD44_RS34335 23e5908558691f7876736c5387edfa40 454 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 331 1.1E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS15765 d9283f27513c64e9b5e3cbbbced3e162 402 Gene3D G3DSA:3.40.50.300 1 246 4.9E-74 T 28-03-2018 SMD44_RS15765 d9283f27513c64e9b5e3cbbbced3e162 402 SUPERFAMILY SSF54631 250 363 5.27E-12 T 28-03-2018 SMD44_RS15765 d9283f27513c64e9b5e3cbbbced3e162 402 SMART SM00382 27 223 2.2E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS15765 d9283f27513c64e9b5e3cbbbced3e162 402 SUPERFAMILY SSF52540 1 240 3.31E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15765 d9283f27513c64e9b5e3cbbbced3e162 402 Pfam PF00005 ABC transporter 19 164 8.0E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS15765 d9283f27513c64e9b5e3cbbbced3e162 402 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS15765 d9283f27513c64e9b5e3cbbbced3e162 402 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 15 366 2.2E-104 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMD44_RS15765 d9283f27513c64e9b5e3cbbbced3e162 402 Gene3D G3DSA:3.10.580.10 247 402 1.1E-12 T 28-03-2018 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 Gene3D G3DSA:3.40.50.2300 2 133 4.0E-37 T 28-03-2018 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 SMART SM00421 155 212 4.0E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 Pfam PF00072 Response regulator receiver domain 5 116 6.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 SUPERFAMILY SSF52172 1 132 1.2E-32 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 Gene3D G3DSA:1.10.10.10 134 217 8.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 SMART SM00448 3 115 3.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.2E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15270 ad5a9fd56c92a612762aadc7c223b4c7 242 SUPERFAMILY SSF46894 149 218 2.75E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 SUPERFAMILY SSF51735 266 468 1.46E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 SUPERFAMILY SSF50129 1 88 2.1E-19 T 28-03-2018 IPR011032 GroES-like SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 Gene3D G3DSA:3.40.50.720 262 493 2.0E-51 T 28-03-2018 SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 SMART SM00829 2 257 1.1E-134 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 79 100 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 Pfam PF08659 KR domain 267 444 3.6E-60 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 Pfam PF13602 Zinc-binding dehydrogenase 130 257 8.8E-21 T 28-03-2018 SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 SUPERFAMILY SSF51735 51 228 9.63E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 Gene3D G3DSA:3.90.180.10 1 260 5.0E-56 T 28-03-2018 SMD44_RS36860 dfc8eea4e920ae83266a897d34fcc940 538 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 267 445 4.2E-58 T 28-03-2018 SMD44_RS31155 cf7fc517122bbf53c6e6b78757ed7e26 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 1.1E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMD44_RS31155 cf7fc517122bbf53c6e6b78757ed7e26 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 1.1E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMD44_RS31155 cf7fc517122bbf53c6e6b78757ed7e26 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 1.1E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMD44_RS31155 cf7fc517122bbf53c6e6b78757ed7e26 156 SUPERFAMILY SSF47240 2 153 1.89E-47 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS31155 cf7fc517122bbf53c6e6b78757ed7e26 156 Gene3D G3DSA:1.20.1260.10 4 156 2.1E-39 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS31155 cf7fc517122bbf53c6e6b78757ed7e26 156 Pfam PF00210 Ferritin-like domain 18 153 3.1E-21 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SMD44_RS31155 cf7fc517122bbf53c6e6b78757ed7e26 156 PIRSF PIRSF005900 1 156 2.3E-44 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMD44_RS31155 cf7fc517122bbf53c6e6b78757ed7e26 156 ProSitePatterns PS00818 Dps protein family signature 1. 38 54 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 SMD44_RS16985 50be7faa4f3c1cd4cdc7062a93bc2eb2 279 Gene3D G3DSA:1.10.150.290 187 256 7.2E-27 T 28-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD44_RS16985 50be7faa4f3c1cd4cdc7062a93bc2eb2 279 SUPERFAMILY SSF53335 12 211 1.09E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS16985 50be7faa4f3c1cd4cdc7062a93bc2eb2 279 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 7 276 45.084 T 28-03-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD44_RS16985 50be7faa4f3c1cd4cdc7062a93bc2eb2 279 Pfam PF13649 Methyltransferase domain 46 142 3.6E-16 T 28-03-2018 SMD44_RS16985 50be7faa4f3c1cd4cdc7062a93bc2eb2 279 Gene3D G3DSA:3.40.50.150 4 170 3.6E-29 T 28-03-2018 SMD44_RS14465 b0ebbebe9d7a01e034f2ce81ac3645e9 311 Gene3D G3DSA:1.20.58.370 1 46 2.9E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMD44_RS14465 b0ebbebe9d7a01e034f2ce81ac3645e9 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 295 6.1E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS14465 b0ebbebe9d7a01e034f2ce81ac3645e9 311 SUPERFAMILY SSF161098 56 297 1.19E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS14465 b0ebbebe9d7a01e034f2ce81ac3645e9 311 Gene3D G3DSA:1.10.3720.10 64 304 5.0E-41 T 28-03-2018 SMD44_RS15960 0763ec721ed1184589c29664fc537c69 167 Pfam PF08592 Domain of unknown function (DUF1772) 6 138 5.5E-18 T 28-03-2018 IPR013901 Anthrone oxygenase SMD44_RS17680 8b69db6d7899935fc109b09f5bfdd49a 135 Gene3D G3DSA:3.10.180.10 22 135 5.6E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS17680 8b69db6d7899935fc109b09f5bfdd49a 135 SUPERFAMILY SSF54593 26 131 2.68E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS27500 3c1831c169ee28b7dcc88059502ec0cd 515 Pfam PF00652 Ricin-type beta-trefoil lectin domain 394 514 2.1E-20 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS27500 3c1831c169ee28b7dcc88059502ec0cd 515 SUPERFAMILY SSF50370 394 514 2.7E-26 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS27500 3c1831c169ee28b7dcc88059502ec0cd 515 Gene3D G3DSA:3.40.50.1110 78 365 1.2E-25 T 28-03-2018 SMD44_RS27500 3c1831c169ee28b7dcc88059502ec0cd 515 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 87 352 1.6E-13 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS27500 3c1831c169ee28b7dcc88059502ec0cd 515 Gene3D G3DSA:2.80.10.50 446 515 1.7E-16 T 28-03-2018 SMD44_RS27500 3c1831c169ee28b7dcc88059502ec0cd 515 Gene3D G3DSA:2.80.10.50 389 445 2.8E-10 T 28-03-2018 SMD44_RS27500 3c1831c169ee28b7dcc88059502ec0cd 515 SMART SM00458 390 514 1.7E-14 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS27500 3c1831c169ee28b7dcc88059502ec0cd 515 SUPERFAMILY SSF52266 83 364 3.66E-52 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS41190 bb111d604f9141e8404f232a72dbb074 428 SUPERFAMILY SSF53901 202 393 5.11E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41190 bb111d604f9141e8404f232a72dbb074 428 Gene3D G3DSA:3.40.47.10 1 242 7.4E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41190 bb111d604f9141e8404f232a72dbb074 428 SMART SM00825 Beta-ketoacyl synthase 10 396 5.9E-13 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS41190 bb111d604f9141e8404f232a72dbb074 428 Gene3D G3DSA:3.40.47.10 246 396 2.9E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41190 bb111d604f9141e8404f232a72dbb074 428 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 238 351 2.9E-31 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS41190 bb111d604f9141e8404f232a72dbb074 428 SUPERFAMILY SSF53901 7 237 6.55E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41190 bb111d604f9141e8404f232a72dbb074 428 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 227 9.9E-26 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 194 37.365 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 PRINTS PR00127 Clp protease catalytic subunit P signature 112 131 3.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 PRINTS PR00127 Clp protease catalytic subunit P signature 20 35 3.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 PRINTS PR00127 Clp protease catalytic subunit P signature 169 188 3.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 PRINTS PR00127 Clp protease catalytic subunit P signature 91 108 3.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 PRINTS PR00127 Clp protease catalytic subunit P signature 60 80 3.3E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 SUPERFAMILY SSF52096 22 194 2.84E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 Gene3D G3DSA:3.90.226.10 22 194 4.1E-37 T 28-03-2018 SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 113 126 - T 28-03-2018 IPR033135 ClpP, histidine active site SMD44_RS40240 25515610af90c55993c1d3d3b064d7ad 208 Pfam PF00574 Clp protease 20 192 6.0E-71 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD44_RS13185 87b45cad65b7becf7c371f0d8cf7bf1e 305 Pfam PF00520 Ion transport protein 26 243 2.4E-41 T 28-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 SMD44_RS13185 87b45cad65b7becf7c371f0d8cf7bf1e 305 Gene3D G3DSA:1.10.287.70 24 242 7.9E-41 T 28-03-2018 SMD44_RS13185 87b45cad65b7becf7c371f0d8cf7bf1e 305 SUPERFAMILY SSF81324 25 241 2.67E-30 T 28-03-2018 SMD44_RS13185 87b45cad65b7becf7c371f0d8cf7bf1e 305 PRINTS PR00169 Potassium channel signature 19 47 1.3E-8 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SMD44_RS13185 87b45cad65b7becf7c371f0d8cf7bf1e 305 PRINTS PR00169 Potassium channel signature 61 84 1.3E-8 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SMD44_RS13185 87b45cad65b7becf7c371f0d8cf7bf1e 305 PRINTS PR00169 Potassium channel signature 88 108 1.3E-8 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SMD44_RS13185 87b45cad65b7becf7c371f0d8cf7bf1e 305 PRINTS PR00169 Potassium channel signature 178 200 1.3E-8 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 SMD44_RS21775 9d00b69f6f074771f04be5704fb676e2 153 Gene3D G3DSA:1.20.1290.10 1 153 2.7E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS21775 9d00b69f6f074771f04be5704fb676e2 153 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 79 1.4E-15 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS21775 9d00b69f6f074771f04be5704fb676e2 153 SUPERFAMILY SSF69118 12 147 1.02E-37 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS21775 9d00b69f6f074771f04be5704fb676e2 153 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 94 6.2E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS22765 9b4ffe10f3b7b02cfcd77da9579a7f27 113 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 8 102 21.786 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD44_RS22765 9b4ffe10f3b7b02cfcd77da9579a7f27 113 Gene3D G3DSA:3.30.1310.10 2 113 3.5E-39 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD44_RS22765 9b4ffe10f3b7b02cfcd77da9579a7f27 113 PIRSF PIRSF004555 6 113 2.1E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD44_RS22765 9b4ffe10f3b7b02cfcd77da9579a7f27 113 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 6 95 8.2E-25 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD44_RS22765 9b4ffe10f3b7b02cfcd77da9579a7f27 113 SUPERFAMILY SSF82607 14 107 8.24E-28 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD44_RS22765 9b4ffe10f3b7b02cfcd77da9579a7f27 113 Pfam PF02575 YbaB/EbfC DNA-binding family 15 103 2.6E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD44_RS17475 73bdf6f9961a9ad42ce47bd6d99b6ea0 312 Gene3D G3DSA:1.10.10.10 2 85 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17475 73bdf6f9961a9ad42ce47bd6d99b6ea0 312 Gene3D G3DSA:3.40.190.10 91 195 6.1E-17 T 28-03-2018 SMD44_RS17475 73bdf6f9961a9ad42ce47bd6d99b6ea0 312 Pfam PF03466 LysR substrate binding domain 90 307 2.9E-36 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS17475 73bdf6f9961a9ad42ce47bd6d99b6ea0 312 SUPERFAMILY SSF53850 90 310 7.74E-33 T 28-03-2018 SMD44_RS17475 73bdf6f9961a9ad42ce47bd6d99b6ea0 312 SUPERFAMILY SSF46785 6 113 4.06E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17475 73bdf6f9961a9ad42ce47bd6d99b6ea0 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 4.5E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS17475 73bdf6f9961a9ad42ce47bd6d99b6ea0 312 Gene3D G3DSA:3.40.190.10 196 282 6.3E-19 T 28-03-2018 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 SUPERFAMILY SSF51621 549 901 1.77E-113 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 SUPERFAMILY SSF56059 16 389 2.0E-131 T 28-03-2018 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Gene3D G3DSA:1.10.189.10 354 402 2.1E-17 T 28-03-2018 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 SUPERFAMILY SSF52009 401 522 1.06E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Gene3D G3DSA:3.30.470.20 256 353 2.0E-19 T 28-03-2018 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Gene3D G3DSA:3.50.30.10 403 547 1.0E-36 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Gene3D G3DSA:3.30.1490.20 16 129 1.4E-34 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 547 899 4.6E-85 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 17 902 0.0 T 28-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Pfam PF00391 PEP-utilising enzyme, mobile domain 432 513 2.0E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 PIRSF PIRSF000853 15 911 0.0 T 28-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 308 363 1.5E-9 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 73 299 4.8E-32 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Gene3D G3DSA:3.20.20.60 560 906 6.3E-110 T 28-03-2018 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 Gene3D G3DSA:1.20.80.30 130 210 1.7E-34 T 28-03-2018 SMD44_RS13475 7712181d1da05afafbd250d39ecf5981 911 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 460 471 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SMD44_RS05020 e4a896c28298bd0a8597077bfaea66b6 188 Gene3D G3DSA:1.10.357.10 4 186 3.2E-22 T 28-03-2018 SMD44_RS05020 e4a896c28298bd0a8597077bfaea66b6 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05020 e4a896c28298bd0a8597077bfaea66b6 188 SUPERFAMILY SSF46689 7 74 4.31E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05035 39baf137024c6af87b0c6c63dab4ac25 284 SUPERFAMILY SSF49899 31 282 7.33E-74 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS05035 39baf137024c6af87b0c6c63dab4ac25 284 Pfam PF00722 Glycosyl hydrolases family 16 73 280 2.4E-44 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 SMD44_RS05035 39baf137024c6af87b0c6c63dab4ac25 284 Gene3D G3DSA:2.60.120.200 34 282 1.6E-74 T 28-03-2018 SMD44_RS17140 38b5be83c8d5b061da71f9612e3bbb0d 224 Gene3D G3DSA:3.40.50.150 10 210 6.2E-27 T 28-03-2018 SMD44_RS17140 38b5be83c8d5b061da71f9612e3bbb0d 224 SUPERFAMILY SSF53335 47 209 2.39E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS17140 38b5be83c8d5b061da71f9612e3bbb0d 224 Pfam PF13489 Methyltransferase domain 48 198 5.1E-12 T 28-03-2018 SMD44_RS18485 c291382a7eb230f08881a2adb7f3cdfd 137 Gene3D G3DSA:3.10.180.10 3 137 1.2E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS18485 c291382a7eb230f08881a2adb7f3cdfd 137 SUPERFAMILY SSF54593 2 134 5.64E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS18485 c291382a7eb230f08881a2adb7f3cdfd 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 2.7E-16 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 SUPERFAMILY SSF47831 30 140 2.22E-19 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 431 449 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 123 1.5E-19 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 547 2.1E-128 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 SUPERFAMILY SSF51621 249 533 1.86E-85 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 431 446 7.9E-18 T 28-03-2018 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 7.9E-18 T 28-03-2018 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 7.9E-18 T 28-03-2018 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 484 496 7.9E-18 T 28-03-2018 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 Gene3D G3DSA:3.50.30.10 145 240 1.6E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 SUPERFAMILY SSF52009 123 237 3.53E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 Gene3D G3DSA:1.10.274.10 27 142 1.8E-21 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 251 524 3.6E-79 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 221 9.3E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 PIRSF PIRSF000732 1 556 7.7E-169 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 SMD44_RS06675 e96feea018abc83059c9445d03459cca 556 Gene3D G3DSA:3.20.20.60 241 555 6.9E-94 T 28-03-2018 SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 40 325 3.6E-121 T 28-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 Gene3D G3DSA:1.50.10.20 322 657 4.4E-115 T 28-03-2018 SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 336 651 2.1E-140 T 28-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 Gene3D G3DSA:1.50.10.20 28 66 0.19 T 28-03-2018 SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 39 651 5.4E-186 T 28-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 SUPERFAMILY SSF48239 323 652 1.65E-103 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 36 652 2.9E-242 T 28-03-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 SUPERFAMILY SSF48239 64 330 1.05E-73 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS35525 d285286b49ca61bbbbf7b17eb9b2e24d 664 Gene3D G3DSA:1.50.10.20 67 321 3.9E-81 T 28-03-2018 SMD44_RS41115 9e203967ced3cff9e2d10ec51cd66ca2 182 SUPERFAMILY SSF54909 1 88 2.01E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS41115 9e203967ced3cff9e2d10ec51cd66ca2 182 Pfam PF03795 YCII-related domain 1 88 1.1E-17 T 28-03-2018 IPR005545 YCII-related SMD44_RS41115 9e203967ced3cff9e2d10ec51cd66ca2 182 Gene3D G3DSA:3.30.70.1060 1 96 8.5E-18 T 28-03-2018 SMD44_RS41115 9e203967ced3cff9e2d10ec51cd66ca2 182 Gene3D G3DSA:3.30.70.1060 114 179 3.8E-5 T 28-03-2018 SMD44_RS04920 e9b535c893a682c58321333d6e145f35 227 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 218 1.9E-28 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD44_RS04920 e9b535c893a682c58321333d6e145f35 227 SUPERFAMILY SSF51695 3 219 2.88E-60 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS04920 e9b535c893a682c58321333d6e145f35 227 Gene3D G3DSA:3.20.20.190 2 224 5.2E-55 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS13225 230bfbeed1aa459b4062db45d24e6f3b 457 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 369 453 7.0E-16 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD44_RS13225 230bfbeed1aa459b4062db45d24e6f3b 457 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 97 260 1.7E-45 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS13225 230bfbeed1aa459b4062db45d24e6f3b 457 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 98 260 9.7E-48 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS06705 88619885f0a1abfdfc45217b62f3c0f8 144 SUPERFAMILY SSF50249 3 117 4.63E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS06705 88619885f0a1abfdfc45217b62f3c0f8 144 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 11 45 5.2E-8 T 28-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMD44_RS06705 88619885f0a1abfdfc45217b62f3c0f8 144 Gene3D G3DSA:2.40.50.140 51 117 1.6E-5 T 28-03-2018 SMD44_RS10045 d27eead2df5a1368982d4f3649edc055 360 Pfam PF04909 Amidohydrolase 194 359 2.7E-7 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS10045 d27eead2df5a1368982d4f3649edc055 360 SUPERFAMILY SSF51556 195 360 1.86E-10 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS10045 d27eead2df5a1368982d4f3649edc055 360 SUPERFAMILY SSF51556 7 166 1.86E-10 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS10045 d27eead2df5a1368982d4f3649edc055 360 Gene3D G3DSA:3.20.20.140 110 359 1.3E-59 T 28-03-2018 SMD44_RS15645 76834105d75a576b9dbc58793b2ebde0 152 Gene3D G3DSA:2.30.30.110 50 150 9.5E-16 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMD44_RS15645 76834105d75a576b9dbc58793b2ebde0 152 SUPERFAMILY SSF50118 52 149 7.63E-10 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMD44_RS15645 76834105d75a576b9dbc58793b2ebde0 152 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 54 148 5.9E-6 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 Gene3D G3DSA:3.40.50.300 15 208 2.0E-8 T 28-03-2018 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 SUPERFAMILY SSF48452 401 439 5.06E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 SUPERFAMILY SSF48452 604 676 5.06E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 SUPERFAMILY SSF48452 724 748 5.06E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 Pfam PF13191 AAA ATPase domain 15 184 2.5E-21 T 28-03-2018 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 Gene3D G3DSA:1.25.40.10 550 882 1.3E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 SUPERFAMILY SSF52540 37 104 1.3E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 SUPERFAMILY SSF52540 149 215 1.3E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 Gene3D G3DSA:1.25.40.10 397 545 2.7E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 SMART SM00028 643 676 0.098 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 SMART SM00028 602 635 250.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS35130 a8c6f1a347f27ef2931283aac99db36a 882 SMART SM00028 404 437 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS26645 ceb07e28a7d2ea3cab303088fd93b581 166 Gene3D G3DSA:1.10.10.10 3 163 2.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26645 ceb07e28a7d2ea3cab303088fd93b581 166 SUPERFAMILY SSF46785 21 160 1.73E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 SUPERFAMILY SSF53649 310 509 4.06E-58 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 SUPERFAMILY SSF53649 24 97 4.06E-58 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 25 508 2.6E-136 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 Gene3D G3DSA:3.40.720.10 310 470 1.1E-18 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 Gene3D G3DSA:3.40.1450.10 97 309 1.4E-48 T 28-03-2018 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 PIRSF PIRSF001492 19 509 2.8E-144 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 24 509 35.784 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 Pfam PF01676 Metalloenzyme superfamily 25 499 1.8E-54 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 102 297 4.1E-44 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS21495 dd6f5ba0240c0d1946e2e265c157d2e6 509 SUPERFAMILY SSF64158 98 308 1.09E-47 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS12435 8841381021a9c41f7ee2eb7273416a32 391 Pfam PF02361 Cobalt transport protein 53 237 8.2E-7 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component SMD44_RS04125 56e039921d7361346785fac81a075dec 221 Gene3D G3DSA:3.40.50.2300 1 135 1.0E-39 T 28-03-2018 SMD44_RS04125 56e039921d7361346785fac81a075dec 221 SMART SM00421 152 209 1.6E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04125 56e039921d7361346785fac81a075dec 221 SUPERFAMILY SSF52172 2 135 2.28E-33 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS04125 56e039921d7361346785fac81a075dec 221 SUPERFAMILY SSF46894 148 215 1.97E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS04125 56e039921d7361346785fac81a075dec 221 SMART SM00448 2 117 2.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS04125 56e039921d7361346785fac81a075dec 221 Pfam PF00072 Response regulator receiver domain 4 117 3.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS04125 56e039921d7361346785fac81a075dec 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04125 56e039921d7361346785fac81a075dec 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04125 56e039921d7361346785fac81a075dec 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04125 56e039921d7361346785fac81a075dec 221 Gene3D G3DSA:1.10.10.10 136 214 7.6E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04125 56e039921d7361346785fac81a075dec 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.3E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.10.129.10 934 1060 1.2E-8 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.10.129.10 2651 2778 5.7E-8 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 406 2.8E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2024 2140 1.1E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF47336 3409 3496 6.67E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF53474 3535 3772 5.91E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF53474 3446 3483 5.91E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.30.70.250 705 750 1.5E-19 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.30.70.250 2425 2465 1.9E-15 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1702 1717 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF00975 Thioesterase domain 3558 3689 3.2E-14 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:1.10.1200.10 3409 3506 1.7E-19 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF52151 2293 2409 5.49E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF52151 2469 2581 5.49E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF00550 Phosphopantetheine attachment site 1677 1742 7.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF00550 Phosphopantetheine attachment site 3418 3483 1.5E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.47.10 26 294 5.7E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.47.10 1758 2028 4.9E-88 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF08659 KR domain 3136 3314 1.2E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF08659 KR domain 1404 1575 1.3E-55 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00823 Phosphopantetheine attachment site 3416 3487 9.7E-24 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00823 Phosphopantetheine attachment site 1675 1747 8.0E-33 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:1.10.1200.10 1647 1753 5.7E-21 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF08990 Erythronolide synthase docking 3 27 3.2E-11 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF47336 1670 1781 1.83E-26 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2145 2258 9.1E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 530 3.9E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3442 3457 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00824 Thioesterase 3560 3771 1.9E-88 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00825 Beta-ketoacyl synthase 1768 2193 1.4E-228 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00825 Beta-ketoacyl synthase 36 459 1.8E-220 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF51735 3133 3333 1.43E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF51735 2937 3122 1.54E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.47.10 2031 2191 1.9E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.47.10 297 457 3.0E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00826 932 1103 5.1E-86 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00826 2652 2821 1.2E-75 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2295 2582 7.4E-112 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 567 865 4.1E-119 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.50.1820 3507 3780 2.2E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF53901 1762 2131 9.73E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.366.10 2291 2424 1.3E-40 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.366.10 563 704 2.1E-42 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF51735 1219 1389 7.09E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF101173 3 33 3.01E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF53901 32 406 7.79E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.366.10 2466 2591 1.1E-29 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM01294 1676 1743 5.7E-6 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF00698 Acyl transferase domain 566 853 4.6E-47 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF00698 Acyl transferase domain 2294 2565 3.4E-55 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.50.720 3129 3371 3.0E-52 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.50.720 1401 1636 3.4E-47 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Gene3D G3DSA:3.40.366.10 751 875 1.2E-25 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF52151 564 689 5.49E-69 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF52151 751 864 5.49E-69 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF14765 Polyketide synthase dehydratase 2652 2931 1.1E-56 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF14765 Polyketide synthase dehydratase 932 1211 3.9E-56 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF55048 694 758 9.42E-13 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1929 1945 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1766 2016 3.8E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 282 8.8E-87 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF55048 2414 2476 1.31E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3136 3316 3.3E-60 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1404 1576 2.3E-57 T 28-03-2018 SMD44_RS02275 051d60e974cf7fa1ec9219ae9b8eb303 3780 SUPERFAMILY SSF51735 1404 1649 2.96E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS11275 b5595a20f2d10427a5ba377544964e9c 145 SUPERFAMILY SSF55961 1 142 3.83E-31 T 28-03-2018 SMD44_RS11275 b5595a20f2d10427a5ba377544964e9c 145 Gene3D G3DSA:3.30.530.20 5 145 6.0E-28 T 28-03-2018 IPR023393 START-like domain SMD44_RS11275 b5595a20f2d10427a5ba377544964e9c 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 142 7.9E-17 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS33010 bb4401f30ae32be6583a7268b00d85fa 207 Gene3D G3DSA:1.20.120.530 65 205 1.3E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS33010 bb4401f30ae32be6583a7268b00d85fa 207 SMART SM00895 78 204 5.6E-14 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS33010 bb4401f30ae32be6583a7268b00d85fa 207 SMART SM00345 10 68 2.4E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS33010 bb4401f30ae32be6583a7268b00d85fa 207 Pfam PF07729 FCD domain 78 202 6.5E-19 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS33010 bb4401f30ae32be6583a7268b00d85fa 207 SUPERFAMILY SSF46785 3 72 7.71E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33010 bb4401f30ae32be6583a7268b00d85fa 207 Gene3D G3DSA:1.10.10.10 1 64 6.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33010 bb4401f30ae32be6583a7268b00d85fa 207 SUPERFAMILY SSF48008 75 203 9.94E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS33010 bb4401f30ae32be6583a7268b00d85fa 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 68 1.7E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 Pfam PF13416 Bacterial extracellular solute-binding protein 84 359 5.1E-26 T 28-03-2018 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 SUPERFAMILY SSF53850 58 398 4.13E-58 T 28-03-2018 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 251 270 1.1E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 137 150 1.1E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 169 185 1.1E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 295 314 1.1E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 121 135 1.1E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 Gene3D G3DSA:3.40.190.10 59 184 2.1E-14 T 28-03-2018 SMD44_RS30655 9fa6d203e59689310ef1f34667966af1 402 Gene3D G3DSA:3.40.190.10 185 346 7.6E-27 T 28-03-2018 SMD44_RS05900 ece4c50c5ea2763290fedece2bf887a2 281 Gene3D G3DSA:3.40.50.1110 2 195 2.0E-28 T 28-03-2018 SMD44_RS05900 ece4c50c5ea2763290fedece2bf887a2 281 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 183 2.7E-20 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS05900 ece4c50c5ea2763290fedece2bf887a2 281 SUPERFAMILY SSF52266 6 192 8.09E-34 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS03875 2c3a692974ac115189ced198e65ac11f 181 Gene3D G3DSA:1.10.10.10 1 88 3.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03875 2c3a692974ac115189ced198e65ac11f 181 Pfam PF10400 Virulence activator alpha C-term 92 174 4.6E-22 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal SMD44_RS03875 2c3a692974ac115189ced198e65ac11f 181 SUPERFAMILY SSF46785 2 176 4.08E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03875 2c3a692974ac115189ced198e65ac11f 181 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 6.6E-10 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 560 644 9.2E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 SUPERFAMILY SSF52540 370 634 1.55E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 279 7.8E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 562 626 9.9E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 Pfam PF00005 ABC transporter 362 510 3.8E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 Gene3D G3DSA:1.10.3720.10 18 281 3.9E-34 T 28-03-2018 SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 SUPERFAMILY SSF161098 85 272 7.06E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 Gene3D G3DSA:3.40.50.300 338 654 3.0E-70 T 28-03-2018 SMD44_RS13650 7a7adcaecc9fd01aaf3bbe595359717a 667 SMART SM00382 370 560 3.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16760 9e32fd69236f654657784c456d1dd842 838 Pfam PF02687 FtsX-like permease family 297 392 1.2E-14 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS16760 9e32fd69236f654657784c456d1dd842 838 Pfam PF02687 FtsX-like permease family 738 831 1.3E-14 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS16760 9e32fd69236f654657784c456d1dd842 838 Pfam PF12704 MacB-like periplasmic core domain 17 236 2.7E-16 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS16760 9e32fd69236f654657784c456d1dd842 838 Pfam PF12704 MacB-like periplasmic core domain 485 680 1.3E-15 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 Gene3D G3DSA:3.20.190.10 1 118 1.0E-25 T 28-03-2018 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 84 6.0E-10 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 SMART SM00898 2 110 1.0E-19 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 124 204 7.6E-10 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 Gene3D G3DSA:1.10.8.50 119 262 8.6E-50 T 28-03-2018 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 ProSitePatterns PS01242 Zinc finger FPG-type signature. 233 261 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 SUPERFAMILY SSF57716 216 262 1.43E-9 T 28-03-2018 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 SUPERFAMILY SSF81624 2 125 1.06E-25 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 SMART SM01232 124 214 1.6E-25 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD44_RS31170 0ec566e37ede54897a68c30ba49a0812 266 SUPERFAMILY SSF46946 123 203 1.7E-20 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 Hamap MF_01987 Ribokinase [rbsK]. 4 302 25.604 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 PRINTS PR00990 Ribokinase signature 173 188 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 PRINTS PR00990 Ribokinase signature 8 29 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 PRINTS PR00990 Ribokinase signature 35 54 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 PRINTS PR00990 Ribokinase signature 106 119 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 PRINTS PR00990 Ribokinase signature 218 229 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 Pfam PF00294 pfkB family carbohydrate kinase 6 294 3.4E-63 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 Gene3D G3DSA:3.40.1190.20 1 302 1.5E-78 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS14785 e4ecad6bf042735cc356696d1ac3298d 302 SUPERFAMILY SSF53613 4 301 2.18E-75 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 Gene3D G3DSA:1.10.10.10 16 91 3.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 SMART SM00345 30 89 4.5E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 SUPERFAMILY SSF46785 22 93 1.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 Pfam PF00155 Aminotransferase class I and II 115 434 4.3E-14 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 Gene3D G3DSA:3.40.640.10 129 394 2.0E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 Gene3D G3DSA:3.90.1150.10 395 491 8.9E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 SUPERFAMILY SSF53383 84 490 1.56E-73 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 2.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 2.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS20645 23ab4002c6232655ac1cf9318b4a6b90 497 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 89 1.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 SUPERFAMILY SSF52540 365 635 2.13E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 SMART SM00028 998 1031 0.018 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 SMART SM00028 957 991 350.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 SUPERFAMILY SSF46894 13 79 5.39E-9 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 Gene3D G3DSA:1.10.10.10 2 96 7.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 SUPERFAMILY SSF48452 950 1098 7.21E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 Pfam PF03704 Bacterial transcriptional activator domain 95 237 8.0E-41 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 SMART SM00862 16 88 4.4E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 Gene3D G3DSA:3.40.50.300 357 519 2.2E-13 T 28-03-2018 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 Gene3D G3DSA:1.25.40.10 97 247 2.8E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 SUPERFAMILY SSF48452 90 241 8.28E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 SMART SM01043 95 237 5.7E-47 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 Gene3D G3DSA:1.10.150.200 947 1002 0.0014 T 28-03-2018 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 78 5.6E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS11985 04af0862855a884bbf7e9b678a1cf217 1244 Gene3D G3DSA:1.25.40.10 1003 1189 3.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34195 047a59aff273d567552946b3916cf4b3 445 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 31 428 3.9E-192 T 28-03-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 SMD44_RS34195 047a59aff273d567552946b3916cf4b3 445 Gene3D G3DSA:3.40.50.720 234 362 1.4E-20 T 28-03-2018 SMD44_RS34195 047a59aff273d567552946b3916cf4b3 445 Pfam PF00107 Zinc-binding dehydrogenase 236 380 5.3E-38 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS34195 047a59aff273d567552946b3916cf4b3 445 Gene3D G3DSA:3.90.180.10 6 233 9.1E-40 T 28-03-2018 SMD44_RS34195 047a59aff273d567552946b3916cf4b3 445 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 113 189 5.9E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS34195 047a59aff273d567552946b3916cf4b3 445 SUPERFAMILY SSF51735 198 391 1.48E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34195 047a59aff273d567552946b3916cf4b3 445 SUPERFAMILY SSF50129 47 230 4.86E-29 T 28-03-2018 IPR011032 GroES-like SMD44_RS34195 047a59aff273d567552946b3916cf4b3 445 SMART SM00829 49 415 3.7E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 PRINTS PR00598 Bacterial regulatory protein MarR family signature 32 48 2.7E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 64 2.7E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 84 2.7E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 117 2.7E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 Gene3D G3DSA:1.10.10.10 2 22 0.052 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 SMART SM00347 9 110 1.1E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 Gene3D G3DSA:1.10.10.10 23 118 1.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 SUPERFAMILY SSF46785 7 118 7.68E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33965 bd34acfae08dcfba934acd201c0f79ca 119 Pfam PF12802 MarR family 14 72 1.5E-12 T 28-03-2018 SMD44_RS15300 60f84db355c90765534d775b76d7987f 199 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 28 197 2.4E-39 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMD44_RS15300 60f84db355c90765534d775b76d7987f 199 SUPERFAMILY SSF81296 28 199 2.1E-57 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS15300 60f84db355c90765534d775b76d7987f 199 Gene3D G3DSA:2.70.50.50 28 199 2.0E-53 T 28-03-2018 SMD44_RS17905 93013bad119850bf561ec3026bd0e1d9 207 Pfam PF05685 Putative restriction endonuclease 38 164 2.8E-17 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS17905 93013bad119850bf561ec3026bd0e1d9 207 Gene3D G3DSA:3.90.1570.10 20 198 8.4E-23 T 28-03-2018 SMD44_RS17905 93013bad119850bf561ec3026bd0e1d9 207 SUPERFAMILY SSF52980 22 162 5.31E-17 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 Pfam PF00571 CBS domain 218 272 0.0064 T 28-03-2018 IPR000644 CBS domain SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 Pfam PF00571 CBS domain 283 335 6.7E-5 T 28-03-2018 IPR000644 CBS domain SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 SUPERFAMILY SSF56176 362 443 6.54E-16 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 Pfam PF01595 Domain of unknown function DUF21 8 201 5.3E-33 T 28-03-2018 IPR002550 Domain of unknown function DUF21 SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 Gene3D G3DSA:3.10.580.10 196 342 1.3E-28 T 28-03-2018 SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 SMART SM01091 357 434 7.3E-18 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 SUPERFAMILY SSF54631 213 347 3.16E-26 T 28-03-2018 SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 Pfam PF03471 Transporter associated domain 364 431 4.6E-15 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS05875 fd713ffb7b217d02c939f8664cc213a8 445 Gene3D G3DSA:3.30.465.10 343 433 3.4E-22 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 SUPERFAMILY SSF48179 189 296 6.8E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 SUPERFAMILY SSF48179 417 501 4.42E-11 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 Gene3D G3DSA:3.40.50.720 4 188 3.8E-52 T 28-03-2018 SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 Gene3D G3DSA:1.10.1040.10 418 504 8.7E-11 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 SUPERFAMILY SSF51735 9 189 2.24E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 Gene3D G3DSA:1.10.1040.10 189 292 1.3E-25 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 188 1.3E-61 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 418 499 2.1E-10 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS21715 5d2233c24d137aaed4862bee96325ee7 504 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 287 1.6E-28 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 1.5E-54 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 SMART SM01382 125 253 6.8E-88 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 Gene3D G3DSA:4.10.950.10 198 273 3.8E-31 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 SUPERFAMILY SSF50249 3 126 6.85E-49 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 SMART SM01383 42 119 1.8E-39 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 PIRSF PIRSF002158 4 275 6.5E-94 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 Gene3D G3DSA:2.30.30.30 120 196 1.8E-28 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 1.5E-127 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 Gene3D G3DSA:2.40.50.140 1 115 4.7E-46 T 28-03-2018 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 2.7E-32 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 SUPERFAMILY SSF50104 127 271 1.32E-56 T 28-03-2018 IPR008991 Translation protein SH3-like domain SMD44_RS25515 2a3505758039592a2e9b788c7de2b11d 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.852 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SMD44_RS11080 d345449c6aa4626dd9b3d8011a2a5314 338 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 47 176 5.5E-65 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SMD44_RS11080 d345449c6aa4626dd9b3d8011a2a5314 338 Gene3D G3DSA:3.40.50.300 21 194 1.3E-25 T 28-03-2018 SMD44_RS11080 d345449c6aa4626dd9b3d8011a2a5314 338 SUPERFAMILY SSF52540 18 291 1.57E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11080 d345449c6aa4626dd9b3d8011a2a5314 338 Gene3D G3DSA:1.10.8.300 208 316 2.0E-32 T 28-03-2018 SMD44_RS11080 d345449c6aa4626dd9b3d8011a2a5314 338 PIRSF PIRSF002849 2 321 2.3E-129 T 28-03-2018 SMD44_RS28545 7940cf24838b8a16f674283a8580e1f1 69 Gene3D G3DSA:1.10.10.60 14 65 1.8E-8 T 28-03-2018 SMD44_RS28545 7940cf24838b8a16f674283a8580e1f1 69 Pfam PF13384 Homeodomain-like domain 40 63 3.9E-6 T 28-03-2018 SMD44_RS28545 7940cf24838b8a16f674283a8580e1f1 69 SUPERFAMILY SSF88659 42 65 7.06E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18095 3143cc70d3e86ab2099fd073cb06e11d 380 Gene3D G3DSA:1.20.140.10 217 380 5.5E-33 T 28-03-2018 SMD44_RS18095 3143cc70d3e86ab2099fd073cb06e11d 380 SUPERFAMILY SSF56645 2 240 9.29E-63 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS18095 3143cc70d3e86ab2099fd073cb06e11d 380 SUPERFAMILY SSF47203 229 378 1.19E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS18095 3143cc70d3e86ab2099fd073cb06e11d 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 216 1.2E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS18095 3143cc70d3e86ab2099fd073cb06e11d 380 Gene3D G3DSA:2.40.110.10 117 216 2.9E-29 T 28-03-2018 SMD44_RS18095 3143cc70d3e86ab2099fd073cb06e11d 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 1.5E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS18095 3143cc70d3e86ab2099fd073cb06e11d 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 374 5.5E-28 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS18095 3143cc70d3e86ab2099fd073cb06e11d 380 Gene3D G3DSA:1.10.540.10 1 116 9.0E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 Gene3D G3DSA:2.60.40.1180 481 572 2.0E-24 T 28-03-2018 SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 SUPERFAMILY SSF51011 486 567 5.31E-16 T 28-03-2018 SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 564 4.8E-23 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 Pfam PF00128 Alpha amylase, catalytic domain 46 402 6.4E-75 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 SMART SM00642 31 433 2.3E-120 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 SUPERFAMILY SSF51445 371 478 1.91E-134 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 SUPERFAMILY SSF51445 20 344 1.91E-134 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 567 1.6E-302 T 28-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 SMD44_RS29440 a43b9add3acc1c718a1f0a5fbb6d35e6 572 Gene3D G3DSA:3.20.20.80 28 480 2.5E-123 T 28-03-2018 SMD44_RS11400 bc86db9317f8a5ee4f18c8c3bfa4b38e 132 Pfam PF12270 Cytochrome c oxidase subunit IV 2 130 3.9E-53 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD44_RS11400 bc86db9317f8a5ee4f18c8c3bfa4b38e 132 PIRSF PIRSF017385 1 131 6.6E-50 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD44_RS29790 47415c8a7f152c4026638cdcfc688095 110 Pfam PF04248 Domain of unknown function (DUF427) 16 103 3.4E-35 T 28-03-2018 IPR007361 Domain of unknown function DUF427 SMD44_RS25470 dcf634d90b6c90dcc6385a2631b2cf80 150 Pfam PF13828 Domain of unknown function (DUF4190) 80 140 6.8E-21 T 28-03-2018 IPR025241 Domain of unknown function DUF4190 SMD44_RS25470 dcf634d90b6c90dcc6385a2631b2cf80 150 Pfam PF08044 Domain of unknown function (DUF1707) 2 53 3.0E-19 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 SMD44_RS09990 8a8629f27fb0c37158559fa011ad741e 154 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 2.3E-47 T 28-03-2018 SMD44_RS09990 8a8629f27fb0c37158559fa011ad741e 154 Gene3D G3DSA:3.90.1010.10 3 154 1.8E-50 T 28-03-2018 SMD44_RS09990 8a8629f27fb0c37158559fa011ad741e 154 Pfam PF01592 NifU-like N terminal domain 6 129 5.1E-27 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 SMD44_RS09990 8a8629f27fb0c37158559fa011ad741e 154 SUPERFAMILY SSF82649 2 143 1.62E-43 T 28-03-2018 SMD44_RS32790 b3ac0b9e5aa2721584c42d7f211e7651 333 SUPERFAMILY SSF48179 187 309 4.76E-9 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS32790 b3ac0b9e5aa2721584c42d7f211e7651 333 Gene3D G3DSA:3.40.50.720 1 186 2.5E-25 T 28-03-2018 SMD44_RS32790 b3ac0b9e5aa2721584c42d7f211e7651 333 SUPERFAMILY SSF51735 1 159 2.81E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS32790 b3ac0b9e5aa2721584c42d7f211e7651 333 Gene3D G3DSA:1.10.1040.10 187 324 1.7E-17 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS32790 b3ac0b9e5aa2721584c42d7f211e7651 333 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 153 2.2E-23 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS32790 b3ac0b9e5aa2721584c42d7f211e7651 333 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 187 310 9.2E-10 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS21090 ad2d51571695a046050a3f93d2d202c2 238 Pfam PF02527 rRNA small subunit methyltransferase G 23 198 4.7E-55 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMD44_RS21090 ad2d51571695a046050a3f93d2d202c2 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 197 4.4E-37 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMD44_RS21090 ad2d51571695a046050a3f93d2d202c2 238 SUPERFAMILY SSF53335 22 208 8.6E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS21090 ad2d51571695a046050a3f93d2d202c2 238 Gene3D G3DSA:3.40.50.150 3 236 4.5E-26 T 28-03-2018 SMD44_RS21090 ad2d51571695a046050a3f93d2d202c2 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 194 23.937 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMD44_RS32100 ae4a0b2eba9778466fc29cc975a568ba 307 SUPERFAMILY SSF51679 4 304 6.41E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS32100 ae4a0b2eba9778466fc29cc975a568ba 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 228 2.0E-92 T 28-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c SMD44_RS32100 ae4a0b2eba9778466fc29cc975a568ba 307 Pfam PF00296 Luciferase-like monooxygenase 8 245 5.7E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS32100 ae4a0b2eba9778466fc29cc975a568ba 307 Gene3D G3DSA:3.20.20.30 2 307 2.8E-72 T 28-03-2018 SMD44_RS32830 58e7d4204c1f7480309692624bc8c396 194 Pfam PF01583 Adenylylsulphate kinase 20 176 7.8E-60 T 28-03-2018 SMD44_RS32830 58e7d4204c1f7480309692624bc8c396 194 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 16 187 7.3E-60 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMD44_RS32830 58e7d4204c1f7480309692624bc8c396 194 Gene3D G3DSA:3.40.50.300 15 194 5.5E-40 T 28-03-2018 SMD44_RS32830 58e7d4204c1f7480309692624bc8c396 194 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 18 192 34.382 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMD44_RS32830 58e7d4204c1f7480309692624bc8c396 194 SUPERFAMILY SSF52540 20 191 5.14E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 Gene3D G3DSA:1.10.10.10 1 79 1.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 Gene3D G3DSA:3.40.190.10 180 301 2.5E-23 T 28-03-2018 SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 Gene3D G3DSA:3.40.190.10 80 179 1.3E-21 T 28-03-2018 SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 Pfam PF03466 LysR substrate binding domain 88 189 1.6E-17 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 Pfam PF03466 LysR substrate binding domain 216 327 5.5E-21 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 SUPERFAMILY SSF46785 1 85 3.15E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 SUPERFAMILY SSF53850 89 180 2.63E-35 T 28-03-2018 SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 SUPERFAMILY SSF53850 212 328 2.63E-35 T 28-03-2018 SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS05890 9eff8ae751b7f832f1e483f7b4ffb749 361 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03445 aac848afb0000bb52da3e34f4e41dce9 307 Gene3D G3DSA:3.90.180.10 229 303 3.2E-4 T 28-03-2018 SMD44_RS03445 aac848afb0000bb52da3e34f4e41dce9 307 Gene3D G3DSA:3.90.180.10 2 135 4.6E-31 T 28-03-2018 SMD44_RS03445 aac848afb0000bb52da3e34f4e41dce9 307 SUPERFAMILY SSF50129 11 146 6.76E-23 T 28-03-2018 IPR011032 GroES-like SMD44_RS03445 aac848afb0000bb52da3e34f4e41dce9 307 Gene3D G3DSA:3.40.50.720 136 228 1.7E-17 T 28-03-2018 SMD44_RS03445 aac848afb0000bb52da3e34f4e41dce9 307 SMART SM00829 10 301 1.3E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS03445 aac848afb0000bb52da3e34f4e41dce9 307 SUPERFAMILY SSF51735 107 275 1.0E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS03445 aac848afb0000bb52da3e34f4e41dce9 307 Pfam PF00107 Zinc-binding dehydrogenase 144 251 8.2E-11 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS43430 18a15e5658cc8bdb74cc0141dc81f173 535 Gene3D G3DSA:1.10.10.10 4 44 0.012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS43430 18a15e5658cc8bdb74cc0141dc81f173 535 Gene3D G3DSA:1.10.10.10 83 424 1.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS43430 18a15e5658cc8bdb74cc0141dc81f173 535 Gene3D G3DSA:1.10.10.10 45 82 0.02 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29260 96b241a037a804ed9ff505ae0613a56a 229 SUPERFAMILY SSF52172 5 145 1.42E-32 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS29260 96b241a037a804ed9ff505ae0613a56a 229 Gene3D G3DSA:1.10.10.10 142 228 4.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29260 96b241a037a804ed9ff505ae0613a56a 229 SMART SM00448 7 120 6.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS29260 96b241a037a804ed9ff505ae0613a56a 229 Pfam PF00072 Response regulator receiver domain 9 120 6.2E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS29260 96b241a037a804ed9ff505ae0613a56a 229 PIRSF PIRSF006171 5 228 1.0E-69 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMD44_RS29260 96b241a037a804ed9ff505ae0613a56a 229 Gene3D G3DSA:3.40.50.2300 6 141 1.2E-29 T 28-03-2018 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 ProSitePatterns PS00455 Putative AMP-binding domain signature. 275 286 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 Gene3D G3DSA:2.30.38.10 445 530 1.0E-9 T 28-03-2018 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 Gene3D G3DSA:3.40.50.980 90 280 9.4E-53 T 28-03-2018 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 40 657 9.4E-294 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 Pfam PF00501 AMP-binding enzyme 104 537 4.0E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 45 97 1.5E-20 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 SUPERFAMILY SSF56801 46 659 4.06E-174 T 28-03-2018 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 Gene3D G3DSA:3.40.50.980 281 444 1.9E-37 T 28-03-2018 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 Pfam PF13193 AMP-binding enzyme C-terminal domain 546 625 1.0E-25 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 25 659 50.718 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 SMD44_RS23225 79e0ef8bc5530f26705d979aeafec2ec 666 Gene3D G3DSA:3.30.300.30 531 644 2.2E-29 T 28-03-2018 SMD44_RS42835 aa81768f6fb933754e39a5a6462ee05f 408 SUPERFAMILY SSF56645 4 236 1.09E-70 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS42835 aa81768f6fb933754e39a5a6462ee05f 408 Gene3D G3DSA:2.40.110.10 123 218 7.6E-32 T 28-03-2018 SMD44_RS42835 aa81768f6fb933754e39a5a6462ee05f 408 SUPERFAMILY SSF47203 242 385 7.25E-31 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS42835 aa81768f6fb933754e39a5a6462ee05f 408 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 378 1.3E-28 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS42835 aa81768f6fb933754e39a5a6462ee05f 408 Gene3D G3DSA:1.10.540.10 2 122 2.5E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS42835 aa81768f6fb933754e39a5a6462ee05f 408 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 217 3.1E-23 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS42835 aa81768f6fb933754e39a5a6462ee05f 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 4.4E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS42835 aa81768f6fb933754e39a5a6462ee05f 408 Gene3D G3DSA:1.20.140.10 219 391 3.3E-36 T 28-03-2018 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 SUPERFAMILY SSF53901 31 407 8.47E-107 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Gene3D G3DSA:3.40.366.10 762 882 2.3E-25 T 28-03-2018 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Pfam PF14765 Polyketide synthase dehydratase 942 1158 1.1E-47 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 7.7E-95 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 540 5.7E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Pfam PF00698 Acyl transferase domain 580 894 1.1E-83 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 SUPERFAMILY SSF52151 579 703 1.28E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 SUPERFAMILY SSF52151 767 864 1.28E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Gene3D G3DSA:3.40.47.10 27 297 8.6E-93 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 582 876 1.7E-120 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 SMART SM00825 Beta-ketoacyl synthase 37 465 7.8E-225 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 2.1E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Gene3D G3DSA:3.10.129.10 948 1073 1.9E-5 T 28-03-2018 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Gene3D G3DSA:3.40.366.10 579 711 7.2E-40 T 28-03-2018 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Gene3D G3DSA:3.30.70.250 712 761 1.3E-19 T 28-03-2018 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 SUPERFAMILY SSF55048 701 766 2.75E-14 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 SMART SM00826 942 1113 3.6E-85 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36815 885ecd76f524c9bc08724eb5ed3c87a5 1363 Gene3D G3DSA:3.40.47.10 300 463 4.2E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS07225 3ba7cb55f27d1c613b3a8fb4e530f3ae 431 SUPERFAMILY SSF102645 211 430 1.16E-70 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMD44_RS07225 3ba7cb55f27d1c613b3a8fb4e530f3ae 431 Gene3D G3DSA:3.40.50.10300 213 431 3.9E-69 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMD44_RS07225 3ba7cb55f27d1c613b3a8fb4e530f3ae 431 SUPERFAMILY SSF52507 32 206 4.97E-59 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS07225 3ba7cb55f27d1c613b3a8fb4e530f3ae 431 Pfam PF02441 Flavoprotein 35 204 1.5E-41 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS07225 3ba7cb55f27d1c613b3a8fb4e530f3ae 431 Gene3D G3DSA:3.40.50.1950 26 212 8.9E-55 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS07225 3ba7cb55f27d1c613b3a8fb4e530f3ae 431 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 35 426 1.7E-122 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 SMD44_RS07225 3ba7cb55f27d1c613b3a8fb4e530f3ae 431 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 216 400 1.3E-70 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMD44_RS01375 de749fde718fec8902639e5521474035 178 Pfam PF01872 RibD C-terminal domain 8 166 7.9E-19 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS01375 de749fde718fec8902639e5521474035 178 Gene3D G3DSA:3.40.430.10 7 174 2.1E-38 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS01375 de749fde718fec8902639e5521474035 178 SUPERFAMILY SSF53597 8 175 4.32E-29 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS27970 37f8cf7451d6f5463cf9c0a143bd0bbe 75 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 7.1E-30 T 28-03-2018 IPR021456 Protein of unknown function DUF3107 SMD44_RS38955 099883b2f3f413695fbdd15083c59cbd 184 Gene3D G3DSA:3.40.50.1820 5 163 3.0E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38955 099883b2f3f413695fbdd15083c59cbd 184 SUPERFAMILY SSF53474 28 151 1.43E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 Gene3D G3DSA:3.20.20.80 276 647 7.9E-135 T 28-03-2018 SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 Gene3D G3DSA:2.60.40.1760 42 275 7.3E-38 T 28-03-2018 SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 439 446 - T 28-03-2018 IPR030458 Glycosyl hydrolases family 31, active site SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 Pfam PF13802 Galactose mutarotase-like 173 238 2.9E-10 T 28-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 SUPERFAMILY SSF74650 86 274 1.16E-15 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 Pfam PF01055 Glycosyl hydrolases family 31 271 712 2.8E-126 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 Gene3D G3DSA:2.60.40.1180 648 708 2.6E-19 T 28-03-2018 SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 SUPERFAMILY SSF51445 279 626 3.91E-82 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS06690 8fac2cf663eefb1c1c0df4658d6c5319 785 SUPERFAMILY SSF51011 628 707 3.52E-19 T 28-03-2018 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 SUPERFAMILY SSF100950 88 245 2.01E-31 T 28-03-2018 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 Gene3D G3DSA:1.10.10.10 5 70 5.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 ProSitePatterns PS00894 DeoR-type HTH domain signature. 18 52 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 50 5.2E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 50 68 5.2E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 SMART SM00420 18 70 1.3E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 SUPERFAMILY SSF46785 16 69 3.21E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 Gene3D G3DSA:3.40.50.1360 84 250 1.3E-44 T 28-03-2018 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 Pfam PF08220 DeoR-like helix-turn-helix domain 18 68 6.3E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 SMART SM01134 84 245 1.3E-66 T 28-03-2018 SMD44_RS02075 325598266a17b39ccd14e9ad8896722e 266 Pfam PF00455 DeoR C terminal sensor domain 88 243 3.0E-50 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain SMD44_RS36620 c22b371ea45f325d7d1c8f494fa9169d 429 Gene3D G3DSA:1.25.40.10 217 311 3.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36620 c22b371ea45f325d7d1c8f494fa9169d 429 Gene3D G3DSA:1.25.40.10 85 216 5.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36620 c22b371ea45f325d7d1c8f494fa9169d 429 Gene3D G3DSA:1.10.260.40 2 72 2.6E-14 T 28-03-2018 SMD44_RS36620 c22b371ea45f325d7d1c8f494fa9169d 429 SMART SM00530 10 64 1.3E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS36620 c22b371ea45f325d7d1c8f494fa9169d 429 SUPERFAMILY SSF48452 161 289 5.31E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36620 c22b371ea45f325d7d1c8f494fa9169d 429 SUPERFAMILY SSF47413 5 67 6.48E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS36620 c22b371ea45f325d7d1c8f494fa9169d 429 Gene3D G3DSA:1.25.40.10 312 428 1.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36620 c22b371ea45f325d7d1c8f494fa9169d 429 Pfam PF13560 Helix-turn-helix domain 6 62 7.3E-10 T 28-03-2018 SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 Pfam PF03466 LysR substrate binding domain 90 297 1.0E-23 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 Gene3D G3DSA:1.10.10.10 1 82 2.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 Gene3D G3DSA:3.40.190.10 175 266 3.3E-17 T 28-03-2018 SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.5E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 Gene3D G3DSA:3.40.190.10 83 174 7.1E-10 T 28-03-2018 SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 SUPERFAMILY SSF53850 90 300 3.08E-22 T 28-03-2018 SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS20895 251737c9560e72be9efbf0a31ceaa784 301 SUPERFAMILY SSF46785 1 76 8.78E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37285 98c6113966097bc7d21c8ea6ae0aa657 393 Gene3D G3DSA:3.60.21.10 47 377 2.7E-56 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS37285 98c6113966097bc7d21c8ea6ae0aa657 393 SMART SM00854 55 304 3.9E-77 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA SMD44_RS37285 98c6113966097bc7d21c8ea6ae0aa657 393 SUPERFAMILY SSF56300 55 358 1.9E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS37285 98c6113966097bc7d21c8ea6ae0aa657 393 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 55 302 2.0E-67 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA SMD44_RS20580 563f2bd49fce05603de242b32f2ad2be 61 Pfam PF12728 Helix-turn-helix domain 6 56 3.2E-7 T 28-03-2018 SMD44_RS20580 563f2bd49fce05603de242b32f2ad2be 61 Gene3D G3DSA:1.10.10.10 7 59 7.5E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17710 f6e31dd4ebd0dfc9eb4ff989892f1652 203 Gene3D G3DSA:1.10.10.60 61 115 3.1E-10 T 28-03-2018 SMD44_RS17710 f6e31dd4ebd0dfc9eb4ff989892f1652 203 SUPERFAMILY SSF46689 12 83 1.07E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS17710 f6e31dd4ebd0dfc9eb4ff989892f1652 203 Gene3D G3DSA:1.10.10.60 1 60 1.6E-16 T 28-03-2018 SMD44_RS17710 f6e31dd4ebd0dfc9eb4ff989892f1652 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 8.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS17710 f6e31dd4ebd0dfc9eb4ff989892f1652 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 8.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS17710 f6e31dd4ebd0dfc9eb4ff989892f1652 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 SUPERFAMILY SSF51905 290 351 2.68E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 SUPERFAMILY SSF51905 24 253 2.68E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 Pfam PF01266 FAD dependent oxidoreductase 24 377 4.7E-51 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 376 386 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 Gene3D G3DSA:3.30.9.10 212 348 3.2E-42 T 28-03-2018 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 Gene3D G3DSA:3.30.9.10 102 211 4.0E-17 T 28-03-2018 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 528 1.6E-36 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 4.5E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 4.5E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 341 347 4.5E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 4.5E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 4.5E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 371 383 4.5E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS25835 1b4c38849c3d8c45de9874e9b398b57e 568 Gene3D G3DSA:3.40.50.720 21 77 1.4E-4 T 28-03-2018 SMD44_RS01840 ad75aac9cea579b5a5ec5d7fd6dbaaee 209 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 15 206 1.1E-68 T 28-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent SMD44_RS01840 ad75aac9cea579b5a5ec5d7fd6dbaaee 209 SUPERFAMILY SSF50475 29 172 3.49E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS01840 ad75aac9cea579b5a5ec5d7fd6dbaaee 209 Gene3D G3DSA:2.30.110.10 26 185 2.9E-30 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS01840 ad75aac9cea579b5a5ec5d7fd6dbaaee 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 124 4.5E-15 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 Pfam PF01494 FAD binding domain 288 360 1.7E-9 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 SUPERFAMILY SSF51905 286 384 1.35E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 SUPERFAMILY SSF51905 5 168 1.35E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 Gene3D G3DSA:3.50.50.60 4 400 1.3E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 330 1.3E-14 T 28-03-2018 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.3E-14 T 28-03-2018 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 1.3E-14 T 28-03-2018 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.3E-14 T 28-03-2018 SMD44_RS33480 17461e79f5a6b4a7a9e682788d0cc727 405 SUPERFAMILY SSF54373 172 292 1.18E-23 T 28-03-2018 SMD44_RS09835 5ee2b491ddb969860aed6783c3418056 417 SUPERFAMILY SSF53474 227 396 1.45E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS09835 5ee2b491ddb969860aed6783c3418056 417 SUPERFAMILY SSF53474 151 193 1.45E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS09835 5ee2b491ddb969860aed6783c3418056 417 SUPERFAMILY SSF53474 87 105 1.45E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS09835 5ee2b491ddb969860aed6783c3418056 417 Gene3D G3DSA:3.40.50.1820 77 412 4.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS09835 5ee2b491ddb969860aed6783c3418056 417 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 126 197 2.7E-7 T 28-03-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 SMD44_RS11255 f99a614053e8ca4f0dd300356994d09e 263 SUPERFAMILY SSF56219 18 252 1.16E-26 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS11255 f99a614053e8ca4f0dd300356994d09e 263 Gene3D G3DSA:3.60.10.10 21 251 1.7E-25 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS11255 f99a614053e8ca4f0dd300356994d09e 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 25 229 3.5E-13 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS23135 587ad057d010b8b79e8edfb5b08053d8 746 Gene3D G3DSA:3.40.710.10 293 705 8.1E-99 T 28-03-2018 SMD44_RS23135 587ad057d010b8b79e8edfb5b08053d8 746 Gene3D G3DSA:1.10.3810.10 67 278 4.2E-76 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS23135 587ad057d010b8b79e8edfb5b08053d8 746 SUPERFAMILY SSF56601 243 265 1.87E-93 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS23135 587ad057d010b8b79e8edfb5b08053d8 746 SUPERFAMILY SSF56601 299 675 1.87E-93 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS23135 587ad057d010b8b79e8edfb5b08053d8 746 SUPERFAMILY SSF53955 64 285 1.69E-69 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS23135 587ad057d010b8b79e8edfb5b08053d8 746 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 630 3.4E-30 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS23135 587ad057d010b8b79e8edfb5b08053d8 746 Pfam PF00912 Transglycosylase 78 261 3.5E-64 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 Pfam PF04851 Type III restriction enzyme, res subunit 181 325 4.7E-12 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 SUPERFAMILY SSF52540 140 342 1.39E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 Pfam PF13625 Helicase conserved C-terminal domain 5 133 6.5E-46 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 352 540 4.3E-48 T 28-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 Gene3D G3DSA:3.40.50.300 169 354 5.8E-27 T 28-03-2018 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 Gene3D G3DSA:3.40.50.300 378 514 6.3E-22 T 28-03-2018 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 SMART SM00487 177 352 4.9E-21 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 SMART SM00490 422 499 1.8E-12 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 474 499 9.7E-35 T 28-03-2018 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 290 310 9.7E-35 T 28-03-2018 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 355 377 9.7E-35 T 28-03-2018 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 455 473 9.7E-35 T 28-03-2018 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 190 212 9.7E-35 T 28-03-2018 SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 SUPERFAMILY SSF52540 289 359 5.01E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18660 58604f20a21411fc5ef900697e20fe9a 547 SUPERFAMILY SSF52540 392 510 5.01E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22150 ab14436b4ad28f46194d3feea7040ab0 358 Gene3D G3DSA:3.60.40.10 87 335 8.3E-25 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS22150 ab14436b4ad28f46194d3feea7040ab0 358 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 154 333 7.0E-30 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS22150 ab14436b4ad28f46194d3feea7040ab0 358 SUPERFAMILY SSF81606 142 333 3.92E-7 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS22150 ab14436b4ad28f46194d3feea7040ab0 358 SMART SM00331 119 334 5.5E-19 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 Gene3D G3DSA:3.30.160.40 224 315 1.3E-22 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 SUPERFAMILY SSF53850 5 219 4.89E-63 T 28-03-2018 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 SUPERFAMILY SSF54782 222 316 1.96E-18 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 308 34.518 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 5.5E-18 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 PRINTS PR00151 Porphobilinogen deaminase signature 145 162 5.5E-18 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 PRINTS PR00151 Porphobilinogen deaminase signature 232 249 5.5E-18 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 5.5E-18 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 212 1.2E-66 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 306 1.5E-16 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 Gene3D G3DSA:3.40.190.10 1 104 1.6E-37 T 28-03-2018 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 308 6.0E-85 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 Gene3D G3DSA:3.40.190.10 105 201 2.4E-32 T 28-03-2018 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 233 249 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS24150 d6b3e230b79e8fec965e41fd7ba032df 319 PIRSF PIRSF001438 1 319 4.5E-108 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS19370 516e4c582b564a0b073225dc9abbfe45 142 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS19370 516e4c582b564a0b073225dc9abbfe45 142 SUPERFAMILY SSF55811 5 135 3.38E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS19370 516e4c582b564a0b073225dc9abbfe45 142 Gene3D G3DSA:3.90.79.10 2 141 7.5E-34 T 28-03-2018 SMD44_RS19370 516e4c582b564a0b073225dc9abbfe45 142 Pfam PF00293 NUDIX domain 9 129 1.2E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS16290 cdbb89abc4d1c20888e9ed332bfda1fd 603 SUPERFAMILY SSF75011 358 581 2.35E-8 T 28-03-2018 SMD44_RS16290 cdbb89abc4d1c20888e9ed332bfda1fd 603 Pfam PF10646 Sporulation and spore germination 206 301 9.8E-7 T 28-03-2018 IPR019606 GerMN domain SMD44_RS16290 cdbb89abc4d1c20888e9ed332bfda1fd 603 SMART SM00909 213 309 2.7E-10 T 28-03-2018 IPR019606 GerMN domain SMD44_RS16290 cdbb89abc4d1c20888e9ed332bfda1fd 603 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 347 602 1.2E-44 T 28-03-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal SMD44_RS16290 cdbb89abc4d1c20888e9ed332bfda1fd 603 Gene3D G3DSA:2.120.10.30 82 586 5.2E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS16290 cdbb89abc4d1c20888e9ed332bfda1fd 603 Hamap MF_01373 Lipoprotein LpqB [lpqB]. 1 603 19.952 T 28-03-2018 IPR023959 Lipoprotein LpqB SMD44_RS06200 8f17a93c4ed452b1a633b85d4af7074f 225 SUPERFAMILY SSF53448 2 198 1.45E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS06200 8f17a93c4ed452b1a633b85d4af7074f 225 Pfam PF00535 Glycosyl transferase family 2 3 117 1.3E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS06200 8f17a93c4ed452b1a633b85d4af7074f 225 Gene3D G3DSA:3.90.550.10 1 213 5.3E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS24115 9756463e5588569e99871fafe3dc29b7 381 SMART SM00563 168 287 2.8E-13 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS24115 9756463e5588569e99871fafe3dc29b7 381 Gene3D G3DSA:3.40.1130.10 123 378 1.3E-24 T 28-03-2018 SMD44_RS24115 9756463e5588569e99871fafe3dc29b7 381 Pfam PF01553 Acyltransferase 153 284 3.5E-15 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS24115 9756463e5588569e99871fafe3dc29b7 381 SUPERFAMILY SSF69593 141 372 1.02E-30 T 28-03-2018 SMD44_RS24115 9756463e5588569e99871fafe3dc29b7 381 PIRSF PIRSF016753 83 381 2.9E-100 T 28-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 Gene3D G3DSA:3.30.9.10 294 384 2.0E-22 T 28-03-2018 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 Gene3D G3DSA:3.30.9.10 185 293 7.1E-16 T 28-03-2018 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 2.1E-43 T 28-03-2018 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 2.1E-43 T 28-03-2018 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 2.1E-43 T 28-03-2018 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 341 2.1E-43 T 28-03-2018 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 2.1E-43 T 28-03-2018 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 23 45 2.1E-43 T 28-03-2018 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 SUPERFAMILY SSF51905 22 187 1.07E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 SUPERFAMILY SSF51905 277 385 1.07E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 Gene3D G3DSA:3.50.50.60 22 184 2.6E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03570 514b38ee3273244db597c2d5fae3f7ec 487 Pfam PF01494 FAD binding domain 23 355 6.7E-85 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS28555 8bd4e44d48b69e9f8f4cbd25fc67054f 359 Gene3D G3DSA:1.10.10.10 2 101 1.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28555 8bd4e44d48b69e9f8f4cbd25fc67054f 359 Gene3D G3DSA:1.10.10.10 270 346 0.042 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28555 8bd4e44d48b69e9f8f4cbd25fc67054f 359 Gene3D G3DSA:1.10.287.700 102 228 0.0013 T 28-03-2018 SMD44_RS28555 8bd4e44d48b69e9f8f4cbd25fc67054f 359 SUPERFAMILY SSF46785 10 114 2.07E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28555 8bd4e44d48b69e9f8f4cbd25fc67054f 359 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 5.8E-22 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS08030 6370b1a3511829e85b2c755c016ce6a7 304 Gene3D G3DSA:1.10.150.20 196 272 1.9E-19 T 28-03-2018 SMD44_RS08030 6370b1a3511829e85b2c755c016ce6a7 304 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 186 267 1.5E-19 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMD44_RS08030 6370b1a3511829e85b2c755c016ce6a7 304 SMART SM00279 183 218 9.7E-11 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SMD44_RS08030 6370b1a3511829e85b2c755c016ce6a7 304 Gene3D G3DSA:3.40.50.1010 1 195 1.1E-54 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS08030 6370b1a3511829e85b2c755c016ce6a7 304 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 180 7.6E-46 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SMD44_RS08030 6370b1a3511829e85b2c755c016ce6a7 304 SMART SM00475 1 273 4.9E-75 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SMD44_RS08030 6370b1a3511829e85b2c755c016ce6a7 304 SUPERFAMILY SSF88723 1 163 6.87E-37 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS08030 6370b1a3511829e85b2c755c016ce6a7 304 SUPERFAMILY SSF47807 186 293 6.43E-21 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 366 593 8.8E-72 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Gene3D G3DSA:3.90.1170.30 1 45 3.6E-18 T 28-03-2018 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Gene3D G3DSA:3.90.1170.30 46 173 7.3E-34 T 28-03-2018 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Gene3D G3DSA:3.90.1170.30 174 294 8.0E-6 T 28-03-2018 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Gene3D G3DSA:4.10.320.10 295 348 9.6E-20 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Pfam PF00364 Biotin-requiring enzyme 132 204 1.7E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Pfam PF00364 Biotin-requiring enzyme 5 76 1.8E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 155 184 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 SUPERFAMILY SSF47005 287 332 4.97E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 602 9.3E-225 T 28-03-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Gene3D G3DSA:3.30.559.10 349 595 1.3E-75 T 28-03-2018 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 SUPERFAMILY SSF52777 355 593 1.16E-76 T 28-03-2018 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 Pfam PF02817 e3 binding domain 295 328 3.5E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 SUPERFAMILY SSF51230 131 224 2.62E-26 T 28-03-2018 IPR011053 Single hybrid motif SMD44_RS11530 8020ba982be8896c1cd2f7fb221d0c92 602 SUPERFAMILY SSF51230 2 96 1.27E-26 T 28-03-2018 IPR011053 Single hybrid motif SMD44_RS02005 05e952f4743c2781336276a32a1434d8 250 Gene3D G3DSA:1.10.10.10 147 250 4.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02005 05e952f4743c2781336276a32a1434d8 250 SMART SM00862 177 248 3.4E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS02005 05e952f4743c2781336276a32a1434d8 250 SUPERFAMILY SSF46894 155 248 2.01E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS02005 05e952f4743c2781336276a32a1434d8 250 SUPERFAMILY SSF52172 20 145 1.42E-38 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS02005 05e952f4743c2781336276a32a1434d8 250 SMART SM00448 23 133 6.7E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS02005 05e952f4743c2781336276a32a1434d8 250 Gene3D G3DSA:3.40.50.2300 19 146 1.4E-34 T 28-03-2018 SMD44_RS02005 05e952f4743c2781336276a32a1434d8 250 Pfam PF00072 Response regulator receiver domain 25 134 5.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS02005 05e952f4743c2781336276a32a1434d8 250 Pfam PF00486 Transcriptional regulatory protein, C terminal 180 248 3.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 Pfam PF03466 LysR substrate binding domain 91 281 6.8E-27 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 SUPERFAMILY SSF46785 2 82 5.45E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 SUPERFAMILY SSF53850 91 285 6.59E-26 T 28-03-2018 SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 Gene3D G3DSA:1.10.10.10 1 82 3.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 Gene3D G3DSA:3.40.190.10 86 171 3.5E-17 T 28-03-2018 SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 Gene3D G3DSA:3.40.190.10 172 256 8.8E-13 T 28-03-2018 SMD44_RS02115 378a200277d8d5f50fcdd8c9d13167ac 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.4E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS08260 dc24d950903f1a62edb232d3a97acc74 452 SUPERFAMILY SSF51556 63 361 1.04E-83 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS08260 dc24d950903f1a62edb232d3a97acc74 452 Gene3D G3DSA:3.20.20.140 74 377 2.5E-59 T 28-03-2018 SMD44_RS08260 dc24d950903f1a62edb232d3a97acc74 452 Pfam PF01979 Amidohydrolase family 60 408 2.3E-61 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS08260 dc24d950903f1a62edb232d3a97acc74 452 SUPERFAMILY SSF51338 5 63 2.1E-33 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS08260 dc24d950903f1a62edb232d3a97acc74 452 SUPERFAMILY SSF51338 360 432 2.1E-33 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS08260 dc24d950903f1a62edb232d3a97acc74 452 Gene3D G3DSA:2.30.40.10 1 73 6.8E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS30355 edf9ec1c526bbd674306c81fad21f671 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 3.3E-26 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30355 edf9ec1c526bbd674306c81fad21f671 57 SUPERFAMILY SSF57829 2 56 7.32E-21 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMD44_RS30355 edf9ec1c526bbd674306c81fad21f671 57 Pfam PF01783 Ribosomal L32p protein family 2 56 5.7E-26 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30355 edf9ec1c526bbd674306c81fad21f671 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 18.859 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS26180 037087a86aa12eabc917b5f277f134c3 323 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 44 311 1.8E-46 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD44_RS26180 037087a86aa12eabc917b5f277f134c3 323 Gene3D G3DSA:3.40.190.10 37 170 4.7E-16 T 28-03-2018 SMD44_RS26180 037087a86aa12eabc917b5f277f134c3 323 Gene3D G3DSA:3.40.190.10 173 323 6.8E-27 T 28-03-2018 SMD44_RS26180 037087a86aa12eabc917b5f277f134c3 323 SUPERFAMILY SSF53850 39 322 7.41E-55 T 28-03-2018 SMD44_RS42170 aa00d9868a9537e4df87826b164c477b 196 SUPERFAMILY SSF52777 18 96 3.89E-18 T 28-03-2018 SMD44_RS42170 aa00d9868a9537e4df87826b164c477b 196 Pfam PF00668 Condensation domain 20 95 2.8E-15 T 28-03-2018 IPR001242 Condensation domain SMD44_RS16165 41798e5bddd0aec2a878624e7d1ea7b3 399 Pfam PF07730 Histidine kinase 195 272 6.3E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS16165 41798e5bddd0aec2a878624e7d1ea7b3 399 Pfam PF13796 Putative sensor 15 133 4.1E-15 T 28-03-2018 IPR025828 Putative sensor domain SMD44_RS16165 41798e5bddd0aec2a878624e7d1ea7b3 399 SMART SM00387 309 399 7.0E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16165 41798e5bddd0aec2a878624e7d1ea7b3 399 SUPERFAMILY SSF55874 284 396 1.14E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16165 41798e5bddd0aec2a878624e7d1ea7b3 399 Gene3D G3DSA:3.30.565.10 271 398 1.2E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 Gene3D G3DSA:3.40.190.10 183 269 1.4E-15 T 28-03-2018 SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 SUPERFAMILY SSF53850 97 292 2.02E-21 T 28-03-2018 SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.3E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 Gene3D G3DSA:3.40.190.10 98 182 1.5E-14 T 28-03-2018 SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 SUPERFAMILY SSF46785 3 84 2.39E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 Gene3D G3DSA:1.10.10.10 1 85 3.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29550 be50df789affd5c1ad13371e0d97dbe3 317 Pfam PF03466 LysR substrate binding domain 106 294 1.5E-23 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS22795 6bc9747e4903c37d407d3ada640b5594 231 SMART SM00448 1 112 7.9E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS22795 6bc9747e4903c37d407d3ada640b5594 231 Gene3D G3DSA:1.10.10.10 121 223 3.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22795 6bc9747e4903c37d407d3ada640b5594 231 Pfam PF00072 Response regulator receiver domain 3 112 6.4E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS22795 6bc9747e4903c37d407d3ada640b5594 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 1.8E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS22795 6bc9747e4903c37d407d3ada640b5594 231 Gene3D G3DSA:3.40.50.2300 1 120 2.2E-29 T 28-03-2018 SMD44_RS22795 6bc9747e4903c37d407d3ada640b5594 231 SMART SM00862 145 217 5.4E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS22795 6bc9747e4903c37d407d3ada640b5594 231 SUPERFAMILY SSF52172 1 170 2.93E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS20080 83bd746f118d0a3feba250a85596f752 145 Pfam PF13581 Histidine kinase-like ATPase domain 18 128 2.8E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20080 83bd746f118d0a3feba250a85596f752 145 SUPERFAMILY SSF55874 39 128 1.04E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20080 83bd746f118d0a3feba250a85596f752 145 Gene3D G3DSA:3.30.565.10 6 140 2.1E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS03605 fb4347f879746e6930fae189f2f0a911 223 Pfam PF00092 von Willebrand factor type A domain 6 174 4.3E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS03605 fb4347f879746e6930fae189f2f0a911 223 SMART SM00327 3 188 2.5E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS03605 fb4347f879746e6930fae189f2f0a911 223 Gene3D G3DSA:3.40.50.410 4 201 9.0E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS03605 fb4347f879746e6930fae189f2f0a911 223 SUPERFAMILY SSF53300 6 189 6.83E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS18110 19e10db2cb70b960a68fa863cb164051 124 Pfam PF01740 STAS domain 9 80 1.7E-11 T 28-03-2018 IPR002645 STAS domain SMD44_RS18110 19e10db2cb70b960a68fa863cb164051 124 SUPERFAMILY SSF52091 4 116 6.08E-21 T 28-03-2018 IPR002645 STAS domain SMD44_RS18110 19e10db2cb70b960a68fa863cb164051 124 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 112 1.5E-18 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD44_RS18110 19e10db2cb70b960a68fa863cb164051 124 Gene3D G3DSA:3.30.750.24 1 120 4.5E-28 T 28-03-2018 IPR002645 STAS domain SMD44_RS16415 ecce6b77263aee2cd2b287079f76f89a 155 SUPERFAMILY SSF55486 37 152 2.31E-23 T 28-03-2018 SMD44_RS16415 ecce6b77263aee2cd2b287079f76f89a 155 Pfam PF06262 Zincin-like metallopeptidase 91 150 1.2E-8 T 28-03-2018 IPR010428 Zincin-like metallopeptidase SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 296 306 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 Pfam PF00082 Subtilase family 255 510 6.9E-56 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 SUPERFAMILY SSF52743 240 525 1.83E-79 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 Gene3D G3DSA:3.50.30.30 800 919 4.0E-15 T 28-03-2018 SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 Gene3D G3DSA:2.60.40.650 1168 1259 0.011 T 28-03-2018 SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 PIRSF PIRSF037852 22 1265 0.0 T 28-03-2018 IPR017296 Peptidase S8A, SAM-P45 SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 Pfam PF02225 PA domain 817 904 5.8E-7 T 28-03-2018 IPR003137 PA domain SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 PRINTS PR00723 Subtilisin serine protease family (S8) signature 466 482 8.0E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 PRINTS PR00723 Subtilisin serine protease family (S8) signature 255 274 8.0E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 PRINTS PR00723 Subtilisin serine protease family (S8) signature 292 305 8.0E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 Gene3D G3DSA:3.40.50.200 229 529 3.2E-87 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS12960 6f90e5ec730da270c76d68f0f1e888e6 1265 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 467 477 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 Pfam PF01016 Ribosomal L27 protein 2 80 1.8E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 SUPERFAMILY SSF110324 2 81 5.23E-31 T 28-03-2018 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 72 1.0E-18 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 27.073 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 1.8E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.4E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.4E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.4E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 Gene3D G3DSA:2.40.50.100 20 83 3.3E-28 T 28-03-2018 SMD44_RS14000 50dfef72c62534a531ace3170101094b 84 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 183 201 9.6E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 517 531 9.6E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 406 422 9.6E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 329 338 9.6E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 9.6E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Gene3D G3DSA:2.70.20.10 362 486 1.5E-40 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 SMART SM00437 287 554 6.7E-120 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Pfam PF01751 Toprim domain 14 134 1.7E-28 T 28-03-2018 IPR006171 TOPRIM domain SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 SMART SM00436 125 213 1.1E-43 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Pfam PF13368 Topoisomerase C-terminal repeat 640 691 1.0E-8 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Pfam PF13368 Topoisomerase C-terminal repeat 699 762 8.4E-13 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Pfam PF13368 Topoisomerase C-terminal repeat 769 819 1.4E-14 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Pfam PF13368 Topoisomerase C-terminal repeat 832 884 2.5E-19 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 SUPERFAMILY SSF56712 12 595 2.62E-180 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Gene3D G3DSA:3.40.50.140 11 155 2.5E-41 T 28-03-2018 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 324 338 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Pfam PF01131 DNA topoisomerase 149 591 4.2E-130 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Gene3D G3DSA:1.10.460.10 156 361 7.8E-43 T 28-03-2018 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Gene3D G3DSA:1.10.460.10 487 937 3.2E-34 T 28-03-2018 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 SMART SM00493 12 125 5.7E-36 T 28-03-2018 IPR006171 TOPRIM domain SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 Hamap MF_00952 DNA topoisomerase 1 [topA]. 12 778 55.811 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 SMD44_RS23335 0934cfcf954f8b28670b5327ca3d2fcf 938 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 14 660 2.3E-243 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 SUPERFAMILY SSF53850 91 287 7.44E-25 T 28-03-2018 SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 Gene3D G3DSA:3.40.190.10 91 178 2.2E-17 T 28-03-2018 SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 Gene3D G3DSA:1.10.10.10 1 89 1.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 Pfam PF03466 LysR substrate binding domain 90 284 1.4E-25 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.2E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 SUPERFAMILY SSF46785 5 87 1.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14330 9594f8c16e3845ed29960c1c1b186bec 297 Gene3D G3DSA:3.40.190.10 179 263 1.6E-7 T 28-03-2018 SMD44_RS31830 5ae2ee800cb60ab71c18ab1136605df3 181 SUPERFAMILY SSF47598 119 165 2.33E-8 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMD44_RS31830 5ae2ee800cb60ab71c18ab1136605df3 181 Gene3D G3DSA:1.10.1220.10 108 176 6.4E-10 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 SUPERFAMILY SSF53850 88 291 2.5E-32 T 28-03-2018 SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 Pfam PF03466 LysR substrate binding domain 88 289 8.0E-30 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 Gene3D G3DSA:1.10.10.10 1 91 8.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 Gene3D G3DSA:3.40.190.10 177 267 9.6E-18 T 28-03-2018 SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 Gene3D G3DSA:3.40.190.10 92 176 4.8E-20 T 28-03-2018 SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.7E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS05515 0ca889e0e41d4f1843e432127bd22664 294 SUPERFAMILY SSF46785 2 84 3.38E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07815 034060c2b15888485eae9ff187c136cc 130 SMART SM00422 1 69 1.6E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS07815 034060c2b15888485eae9ff187c136cc 130 Pfam PF13411 MerR HTH family regulatory protein 1 64 3.6E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS07815 034060c2b15888485eae9ff187c136cc 130 Gene3D G3DSA:1.10.1660.10 1 53 6.0E-17 T 28-03-2018 SMD44_RS07815 034060c2b15888485eae9ff187c136cc 130 SUPERFAMILY SSF46955 1 115 1.9E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS07815 034060c2b15888485eae9ff187c136cc 130 Gene3D G3DSA:1.10.1660.10 54 126 2.6E-12 T 28-03-2018 SMD44_RS03650 979210f9fc3b12e8b87258c38ad198f6 311 SUPERFAMILY SSF46785 88 189 6.16E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03650 979210f9fc3b12e8b87258c38ad198f6 311 Gene3D G3DSA:1.10.10.10 240 274 4.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03650 979210f9fc3b12e8b87258c38ad198f6 311 Pfam PF12802 MarR family 104 163 4.3E-9 T 28-03-2018 SMD44_RS03650 979210f9fc3b12e8b87258c38ad198f6 311 Gene3D G3DSA:1.10.10.10 48 233 2.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03650 979210f9fc3b12e8b87258c38ad198f6 311 Gene3D G3DSA:1.10.10.60 3 46 2.6E-10 T 28-03-2018 SMD44_RS03650 979210f9fc3b12e8b87258c38ad198f6 311 Pfam PF13936 Helix-turn-helix domain 5 45 6.3E-13 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain SMD44_RS28285 761b0823896cff80827a478568a913c7 326 Gene3D G3DSA:1.25.40.10 5 145 8.1E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28285 761b0823896cff80827a478568a913c7 326 SUPERFAMILY SSF48452 14 111 1.8E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Pfam PF00698 Acyl transferase domain 582 898 8.4E-60 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Pfam PF08990 Erythronolide synthase docking 2 27 8.0E-13 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 SUPERFAMILY SSF101173 3 34 3.66E-8 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 546 1.7E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 407 8.9E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 SUPERFAMILY SSF55048 705 769 8.37E-14 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 282 7.6E-90 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 582 879 2.9E-125 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Gene3D G3DSA:3.40.366.10 760 878 8.6E-30 T 28-03-2018 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Gene3D G3DSA:3.30.70.250 715 759 6.4E-21 T 28-03-2018 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 SMART SM00825 Beta-ketoacyl synthase 36 462 1.6E-221 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 SUPERFAMILY SSF52151 770 864 7.32E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 SUPERFAMILY SSF52151 579 706 7.32E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Gene3D G3DSA:3.40.366.10 578 714 1.4E-47 T 28-03-2018 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Gene3D G3DSA:3.40.47.10 26 294 5.1E-88 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 Gene3D G3DSA:3.40.47.10 297 460 2.2E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36850 604f68e439a2d16ad93093c6bcad8a40 1010 SUPERFAMILY SSF53901 30 397 4.16E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 Gene3D G3DSA:1.10.580.10 270 363 2.7E-11 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 PIRSF PIRSF001369 6 380 1.3E-120 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 13 376 6.1E-140 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 Pfam PF00285 Citrate synthase, C-terminal domain 14 365 5.9E-122 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 ProSitePatterns PS00480 Citrate synthase signature. 263 275 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 Gene3D G3DSA:1.10.580.10 19 269 9.5E-93 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 SUPERFAMILY SSF48256 11 376 9.03E-124 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 PRINTS PR00143 Citrate synthase signature 132 145 4.3E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 PRINTS PR00143 Citrate synthase signature 203 231 4.3E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 PRINTS PR00143 Citrate synthase signature 181 196 4.3E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 PRINTS PR00143 Citrate synthase signature 336 350 4.3E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 PRINTS PR00143 Citrate synthase signature 256 276 4.3E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS01025 360f55123b15c9070c6531d6f2d75388 381 PRINTS PR00143 Citrate synthase signature 316 332 4.3E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 Pfam PF08448 PAS fold 65 173 2.7E-8 T 28-03-2018 IPR013656 PAS fold-4 SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 Gene3D G3DSA:3.60.40.10 182 419 4.6E-41 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 SUPERFAMILY SSF55874 465 551 1.93E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 SMART SM00331 206 419 3.6E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 SUPERFAMILY SSF55785 75 181 3.98E-5 T 28-03-2018 IPR000014 PAS domain SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 Gene3D G3DSA:3.30.565.10 429 556 4.4E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 Gene3D G3DSA:3.30.450.20 38 181 2.3E-19 T 28-03-2018 SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 236 418 2.4E-48 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 Pfam PF13581 Histidine kinase-like ATPase domain 443 533 3.7E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19555 f9020d45973bf075cd418e25741eac80 556 SUPERFAMILY SSF81606 222 417 1.28E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS41200 9b9602990ddccd6e7924b71f63548270 379 Gene3D G3DSA:3.40.47.10 4 216 5.6E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41200 9b9602990ddccd6e7924b71f63548270 379 SMART SM00825 Beta-ketoacyl synthase 9 379 1.4E-11 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS41200 9b9602990ddccd6e7924b71f63548270 379 SUPERFAMILY SSF53901 5 213 5.76E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41200 9b9602990ddccd6e7924b71f63548270 379 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 222 332 3.5E-22 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS41200 9b9602990ddccd6e7924b71f63548270 379 Gene3D G3DSA:3.40.47.10 228 379 1.0E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41200 9b9602990ddccd6e7924b71f63548270 379 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 213 1.2E-21 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS41200 9b9602990ddccd6e7924b71f63548270 379 SUPERFAMILY SSF53901 185 378 1.31E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35215 b842cb2623e566c56b5fdd3c025d0a7b 357 Pfam PF01068 ATP dependent DNA ligase domain 11 197 2.5E-34 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMD44_RS35215 b842cb2623e566c56b5fdd3c025d0a7b 357 Gene3D G3DSA:2.40.50.140 197 344 2.7E-30 T 28-03-2018 SMD44_RS35215 b842cb2623e566c56b5fdd3c025d0a7b 357 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 SMD44_RS35215 b842cb2623e566c56b5fdd3c025d0a7b 357 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 330 8.5E-15 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SMD44_RS35215 b842cb2623e566c56b5fdd3c025d0a7b 357 SUPERFAMILY SSF50249 200 339 4.88E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS35215 b842cb2623e566c56b5fdd3c025d0a7b 357 SUPERFAMILY SSF56091 6 197 3.6E-38 T 28-03-2018 SMD44_RS35215 b842cb2623e566c56b5fdd3c025d0a7b 357 Gene3D G3DSA:3.30.1490.70 142 196 4.0E-7 T 28-03-2018 SMD44_RS35215 b842cb2623e566c56b5fdd3c025d0a7b 357 Gene3D G3DSA:3.30.470.30 2 141 2.2E-27 T 28-03-2018 SMD44_RS02340 8286f79c1e8af6c162f9fa56a4fd7fb1 228 SUPERFAMILY SSF48008 83 217 1.39E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS02340 8286f79c1e8af6c162f9fa56a4fd7fb1 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 2.4E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS02340 8286f79c1e8af6c162f9fa56a4fd7fb1 228 Gene3D G3DSA:1.10.10.10 1 77 6.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02340 8286f79c1e8af6c162f9fa56a4fd7fb1 228 SUPERFAMILY SSF46785 7 88 1.44E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02340 8286f79c1e8af6c162f9fa56a4fd7fb1 228 Pfam PF07729 FCD domain 87 212 2.3E-27 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS02340 8286f79c1e8af6c162f9fa56a4fd7fb1 228 SMART SM00345 17 75 2.6E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS02340 8286f79c1e8af6c162f9fa56a4fd7fb1 228 Gene3D G3DSA:1.20.120.530 78 225 1.8E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS02340 8286f79c1e8af6c162f9fa56a4fd7fb1 228 SMART SM00895 86 213 1.8E-24 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS17510 404a8fd5907ba10a3be625ccdca7efdf 396 Pfam PF00144 Beta-lactamase 41 367 6.2E-63 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS17510 404a8fd5907ba10a3be625ccdca7efdf 396 SUPERFAMILY SSF56601 42 372 3.65E-78 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS17510 404a8fd5907ba10a3be625ccdca7efdf 396 Gene3D G3DSA:3.40.710.10 32 378 4.1E-78 T 28-03-2018 SMD44_RS30810 09a86496fbc195c4787cc40db543555e 601 Gene3D G3DSA:2.60.120.260 449 595 6.6E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS30810 09a86496fbc195c4787cc40db543555e 601 Gene3D G3DSA:2.60.40.1180 363 448 1.1E-4 T 28-03-2018 SMD44_RS30810 09a86496fbc195c4787cc40db543555e 601 SMART SM00812 40 403 0.0029 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMD44_RS30810 09a86496fbc195c4787cc40db543555e 601 SUPERFAMILY SSF49785 466 575 6.45E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS30810 09a86496fbc195c4787cc40db543555e 601 SUPERFAMILY SSF51445 44 347 1.16E-20 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS30810 09a86496fbc195c4787cc40db543555e 601 Gene3D G3DSA:3.20.20.80 37 352 2.1E-31 T 28-03-2018 SMD44_RS30810 09a86496fbc195c4787cc40db543555e 601 Pfam PF01120 Alpha-L-fucosidase 85 340 2.9E-11 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 316 8.8E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 440 1.0E-20 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.7E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 255 1.7E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 1.7E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 1.7E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.7E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 Gene3D G3DSA:3.30.390.30 335 459 3.6E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 2.0E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.0E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.0E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 2.0E-18 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 Gene3D G3DSA:3.50.50.60 1 142 6.4E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 SUPERFAMILY SSF55424 332 454 3.78E-33 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 Gene3D G3DSA:3.40.50.720 143 321 1.9E-32 T 28-03-2018 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 SUPERFAMILY SSF51905 154 323 9.56E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32390 7555c095961656b8c26ecd572cb74a04 461 SUPERFAMILY SSF51905 3 200 4.44E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08595 d7504f17e1c4514f8db158fc10780169 361 Gene3D G3DSA:3.90.180.10 4 174 4.3E-46 T 28-03-2018 SMD44_RS08595 d7504f17e1c4514f8db158fc10780169 361 Pfam PF00107 Zinc-binding dehydrogenase 191 310 2.6E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS08595 d7504f17e1c4514f8db158fc10780169 361 SUPERFAMILY SSF51735 153 325 2.78E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS08595 d7504f17e1c4514f8db158fc10780169 361 SUPERFAMILY SSF50129 3 187 6.24E-50 T 28-03-2018 IPR011032 GroES-like SMD44_RS08595 d7504f17e1c4514f8db158fc10780169 361 Gene3D G3DSA:3.40.50.10730 175 302 2.5E-32 T 28-03-2018 SMD44_RS08595 d7504f17e1c4514f8db158fc10780169 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 117 1.4E-22 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS08595 d7504f17e1c4514f8db158fc10780169 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS08595 d7504f17e1c4514f8db158fc10780169 361 SMART SM00829 13 359 5.7E-10 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 2.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 2.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 2.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 Gene3D G3DSA:3.40.50.720 52 258 2.3E-61 T 28-03-2018 SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 Gene3D G3DSA:3.40.50.720 10 51 2.0E-5 T 28-03-2018 SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 4.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 4.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 4.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 255 6.2E-65 T 28-03-2018 SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS35115 51263cf45c79964148b780325973e1dc 260 SUPERFAMILY SSF51735 14 256 1.14E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Gene3D G3DSA:3.30.70.240 578 654 1.6E-10 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Pfam PF00009 Elongation factor Tu GTP binding domain 14 260 1.3E-56 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 SUPERFAMILY SSF52540 12 260 1.24E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Pfam PF14492 Elongation Factor G, domain II 364 436 9.5E-7 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Gene3D G3DSA:2.40.30.10 267 362 9.2E-21 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 175 1.5E-29 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Pfam PF00679 Elongation factor G C-terminus 570 652 2.4E-12 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 SUPERFAMILY SSF50447 244 354 3.03E-16 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 SUPERFAMILY SSF54211 455 567 2.35E-12 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Gene3D G3DSA:3.40.50.300 185 266 5.1E-5 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Gene3D G3DSA:3.40.50.300 5 178 5.9E-37 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Gene3D G3DSA:3.30.230.10 443 577 3.4E-15 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 SUPERFAMILY SSF54980 365 436 6.83E-11 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Pfam PF03764 Elongation factor G, domain IV 456 566 2.8E-11 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 SMART SM00889 440 567 4.3E-8 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR00315 GTP-binding elongation factor signature 98 109 3.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR00315 GTP-binding elongation factor signature 134 143 3.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR00315 GTP-binding elongation factor signature 16 29 3.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 478 492 1.2E-24 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 120 143 1.2E-24 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 234 256 1.2E-24 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 493 515 1.2E-24 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 288 314 1.2E-24 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 Gene3D G3DSA:3.30.70.870 364 438 2.7E-11 T 28-03-2018 SMD44_RS28490 5c347a4868bf86df783a164c810ebaee 679 SUPERFAMILY SSF54980 570 656 3.12E-12 T 28-03-2018 IPR035647 EF-G domain III/V-like SMD44_RS08080 69cfc99558d202716327c131c7dc0f38 296 SUPERFAMILY SSF111331 5 295 5.67E-69 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD44_RS08080 69cfc99558d202716327c131c7dc0f38 296 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 295 1.8E-36 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase SMD44_RS08080 69cfc99558d202716327c131c7dc0f38 296 SMART SM00046 4 131 9.1E-5 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD44_RS08080 69cfc99558d202716327c131c7dc0f38 296 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 130 8.8E-25 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD44_RS08080 69cfc99558d202716327c131c7dc0f38 296 Gene3D G3DSA:3.40.50.10330 2 135 1.7E-27 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMD44_RS02615 30334c302966183da80e8acf5e401e1f 379 Pfam PF13365 Trypsin-like peptidase domain 194 350 4.6E-13 T 28-03-2018 SMD44_RS02615 30334c302966183da80e8acf5e401e1f 379 Gene3D G3DSA:2.40.10.10 261 379 8.5E-24 T 28-03-2018 SMD44_RS02615 30334c302966183da80e8acf5e401e1f 379 SUPERFAMILY SSF50494 174 375 3.82E-23 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS02615 30334c302966183da80e8acf5e401e1f 379 Gene3D G3DSA:2.40.10.10 97 260 4.2E-6 T 28-03-2018 SMD44_RS20865 7aa4527847c54093dcfd3aca1ef65b81 237 Pfam PF01614 Bacterial transcriptional regulator 122 235 2.9E-14 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS20865 7aa4527847c54093dcfd3aca1ef65b81 237 SUPERFAMILY SSF55781 70 229 1.9E-20 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS20865 7aa4527847c54093dcfd3aca1ef65b81 237 Gene3D G3DSA:3.30.450.40 63 236 2.5E-23 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS20865 7aa4527847c54093dcfd3aca1ef65b81 237 Pfam PF09339 IclR helix-turn-helix domain 1 46 1.1E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS20865 7aa4527847c54093dcfd3aca1ef65b81 237 SUPERFAMILY SSF46785 1 63 1.46E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20865 7aa4527847c54093dcfd3aca1ef65b81 237 Gene3D G3DSA:1.10.10.10 1 53 2.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10965 51c3b3685689164a755a8bb17a4d1bb1 238 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 127 135 8.0E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD44_RS10965 51c3b3685689164a755a8bb17a4d1bb1 238 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 169 184 8.0E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD44_RS10965 51c3b3685689164a755a8bb17a4d1bb1 238 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 207 223 8.0E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD44_RS10965 51c3b3685689164a755a8bb17a4d1bb1 238 ProSitePatterns PS00855 Signal peptidases II signature. 172 184 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD44_RS10965 51c3b3685689164a755a8bb17a4d1bb1 238 TIGRFAM TIGR00077 lspA: signal peptidase II 79 226 1.3E-23 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD44_RS10965 51c3b3685689164a755a8bb17a4d1bb1 238 Pfam PF01252 Signal peptidase (SPase) II 89 226 1.5E-27 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD44_RS10965 51c3b3685689164a755a8bb17a4d1bb1 238 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 80 232 14.493 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD44_RS06855 5f3515b87fc40b62525aa6e291177f8c 139 SMART SM00248 86 115 0.026 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMD44_RS06855 5f3515b87fc40b62525aa6e291177f8c 139 SMART SM00248 53 82 0.019 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMD44_RS06855 5f3515b87fc40b62525aa6e291177f8c 139 SUPERFAMILY SSF48403 27 125 1.71E-18 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SMD44_RS06855 5f3515b87fc40b62525aa6e291177f8c 139 Pfam PF12796 Ankyrin repeats (3 copies) 32 114 4.6E-10 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SMD44_RS06855 5f3515b87fc40b62525aa6e291177f8c 139 Gene3D G3DSA:1.25.40.20 19 136 6.1E-23 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SMD44_RS30610 2b808746b00a5eda2b8e83a8f7499bfd 263 Pfam PF07398 MDMPI C-terminal domain 150 254 5.1E-14 T 28-03-2018 IPR010872 MDMPI C-terminal SMD44_RS30610 2b808746b00a5eda2b8e83a8f7499bfd 263 Gene3D G3DSA:1.20.120.450 5 145 1.6E-15 T 28-03-2018 SMD44_RS30610 2b808746b00a5eda2b8e83a8f7499bfd 263 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 236 1.9E-24 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS30610 2b808746b00a5eda2b8e83a8f7499bfd 263 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 138 9.2E-17 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS30610 2b808746b00a5eda2b8e83a8f7499bfd 263 SUPERFAMILY SSF109854 6 144 3.48E-6 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS31260 08bcb879c782482d827af075825a2478 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 106 1.7E-20 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD44_RS31260 08bcb879c782482d827af075825a2478 215 Gene3D G3DSA:1.10.3720.10 5 213 1.1E-35 T 28-03-2018 SMD44_RS31260 08bcb879c782482d827af075825a2478 215 SUPERFAMILY SSF161098 10 197 9.94E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS31260 08bcb879c782482d827af075825a2478 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 211 3.0E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15060 2ace9ae3449d8440371c692d972cf2a3 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 258 5.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15060 2ace9ae3449d8440371c692d972cf2a3 271 Gene3D G3DSA:1.10.3720.10 5 259 3.4E-35 T 28-03-2018 SMD44_RS15060 2ace9ae3449d8440371c692d972cf2a3 271 SUPERFAMILY SSF161098 6 271 1.78E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS04575 062305bc45fb7b323f9d730f9ca3401b 120 Pfam PF00196 Bacterial regulatory proteins, luxR family 43 98 1.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04575 062305bc45fb7b323f9d730f9ca3401b 120 SUPERFAMILY SSF46894 30 104 3.74E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS04575 062305bc45fb7b323f9d730f9ca3401b 120 SMART SM00421 41 98 5.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04575 062305bc45fb7b323f9d730f9ca3401b 120 Gene3D G3DSA:1.10.10.10 10 107 2.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38900 7265ffba18b2a0e8817dfb530f27e33e 768 SUPERFAMILY SSF52777 23 231 2.56E-28 T 28-03-2018 SMD44_RS38900 7265ffba18b2a0e8817dfb530f27e33e 768 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 355 521 3.8E-35 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase SMD44_RS38900 7265ffba18b2a0e8817dfb530f27e33e 768 SUPERFAMILY SSF52777 220 498 3.45E-28 T 28-03-2018 SMD44_RS38900 7265ffba18b2a0e8817dfb530f27e33e 768 Gene3D G3DSA:3.30.559.10 26 227 7.7E-23 T 28-03-2018 SMD44_RS38900 7265ffba18b2a0e8817dfb530f27e33e 768 Pfam PF00668 Condensation domain 48 407 9.5E-34 T 28-03-2018 IPR001242 Condensation domain SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 SUPERFAMILY SSF140490 336 435 7.85E-38 T 28-03-2018 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 SUPERFAMILY SSF142019 20 251 5.75E-86 T 28-03-2018 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 342 425 1.6E-32 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 SMART SM00928 340 385 4.2E-26 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 Gene3D G3DSA:3.10.560.10 249 394 3.7E-4 T 28-03-2018 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 353 364 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 Pfam PF10531 SLBB domain 256 302 1.8E-7 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 23 426 3.8E-193 T 28-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 179 194 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 60 231 9.5E-46 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25045 c36f982ae2fce33cb7d2a0be64f296ea 455 SUPERFAMILY SSF142984 254 335 2.62E-21 T 28-03-2018 SMD44_RS26675 a25540ca4d1b08b9ee83870c5327508b 450 SUPERFAMILY SSF53756 111 311 3.77E-5 T 28-03-2018 SMD44_RS23675 cc9285bc175e60974d3cc9cc6a070f68 163 Gene3D G3DSA:3.90.80.10 1 161 7.7E-53 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMD44_RS23675 cc9285bc175e60974d3cc9cc6a070f68 163 Pfam PF00719 Inorganic pyrophosphatase 5 157 5.8E-53 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMD44_RS23675 cc9285bc175e60974d3cc9cc6a070f68 163 SUPERFAMILY SSF50324 3 157 1.57E-57 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMD44_RS23675 cc9285bc175e60974d3cc9cc6a070f68 163 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.736 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMD44_RS23675 cc9285bc175e60974d3cc9cc6a070f68 163 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMD44_RS24495 cd4434db2d093f9572c4cfad8f12d7b9 623 Gene3D G3DSA:3.30.300.30 478 612 1.9E-12 T 28-03-2018 SMD44_RS24495 cd4434db2d093f9572c4cfad8f12d7b9 623 Gene3D G3DSA:3.40.50.980 13 209 1.7E-41 T 28-03-2018 SMD44_RS24495 cd4434db2d093f9572c4cfad8f12d7b9 623 SUPERFAMILY SSF56801 11 308 9.55E-120 T 28-03-2018 SMD44_RS24495 cd4434db2d093f9572c4cfad8f12d7b9 623 SUPERFAMILY SSF56801 353 611 9.55E-120 T 28-03-2018 SMD44_RS24495 cd4434db2d093f9572c4cfad8f12d7b9 623 Gene3D G3DSA:3.40.50.980 210 404 5.8E-39 T 28-03-2018 SMD44_RS24495 cd4434db2d093f9572c4cfad8f12d7b9 623 Gene3D G3DSA:2.30.38.10 405 476 1.9E-20 T 28-03-2018 SMD44_RS24495 cd4434db2d093f9572c4cfad8f12d7b9 623 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS24495 cd4434db2d093f9572c4cfad8f12d7b9 623 Pfam PF00501 AMP-binding enzyme 21 483 1.5E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS27355 05e1079eb891f68f9fca0768ef13490d 446 Pfam PF00437 Type II/IV secretion system protein 87 362 2.3E-88 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMD44_RS27355 05e1079eb891f68f9fca0768ef13490d 446 Gene3D G3DSA:3.30.450.90 81 183 1.6E-34 T 28-03-2018 SMD44_RS27355 05e1079eb891f68f9fca0768ef13490d 446 SUPERFAMILY SSF52540 71 368 9.34E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27355 05e1079eb891f68f9fca0768ef13490d 446 Gene3D G3DSA:3.40.50.300 184 385 7.4E-18 T 28-03-2018 SMD44_RS30710 b71583788c24653e05adf88e8906f5ba 501 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS30710 b71583788c24653e05adf88e8906f5ba 501 SUPERFAMILY SSF53720 14 485 2.36E-159 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS30710 b71583788c24653e05adf88e8906f5ba 501 Gene3D G3DSA:3.40.605.10 2 274 3.4E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS30710 b71583788c24653e05adf88e8906f5ba 501 Pfam PF00171 Aldehyde dehydrogenase family 25 481 6.2E-168 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS30710 b71583788c24653e05adf88e8906f5ba 501 Gene3D G3DSA:3.40.309.10 275 467 9.2E-71 T 28-03-2018 SMD44_RS30710 b71583788c24653e05adf88e8906f5ba 501 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS12420 29cf3ce63ae36a6d18c74353c27c6c77 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 267 5.6E-19 T 28-03-2018 SMD44_RS12420 29cf3ce63ae36a6d18c74353c27c6c77 277 SUPERFAMILY SSF51735 19 269 7.94E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS12420 29cf3ce63ae36a6d18c74353c27c6c77 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12420 29cf3ce63ae36a6d18c74353c27c6c77 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 251 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12420 29cf3ce63ae36a6d18c74353c27c6c77 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12420 29cf3ce63ae36a6d18c74353c27c6c77 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12420 29cf3ce63ae36a6d18c74353c27c6c77 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12420 29cf3ce63ae36a6d18c74353c27c6c77 277 Gene3D G3DSA:3.40.50.720 2 270 2.4E-40 T 28-03-2018 SMD44_RS19220 477add8a30f577167d6384623af9becb 304 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 78 3.1E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19220 477add8a30f577167d6384623af9becb 304 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 4.3E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19220 477add8a30f577167d6384623af9becb 304 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 4.3E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19220 477add8a30f577167d6384623af9becb 304 SMART SM00345 27 87 2.4E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19220 477add8a30f577167d6384623af9becb 304 SUPERFAMILY SSF46785 20 91 1.76E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19220 477add8a30f577167d6384623af9becb 304 Gene3D G3DSA:1.10.10.10 10 89 8.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 307 2.6E-62 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 Gene3D G3DSA:2.40.50.100 548 622 7.1E-13 T 28-03-2018 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 577 594 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 SUPERFAMILY SSF56059 83 319 3.71E-58 T 28-03-2018 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 SUPERFAMILY SSF52440 1 113 7.91E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.5E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 271 278 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 Gene3D G3DSA:3.40.50.20 1 119 4.0E-49 T 28-03-2018 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 SUPERFAMILY SSF51230 544 620 1.44E-16 T 28-03-2018 IPR011053 Single hybrid motif SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 SMART SM00878 320 424 1.7E-46 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 Pfam PF02785 Biotin carboxylase C-terminal domain 320 424 8.1E-30 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 Pfam PF00364 Biotin-requiring enzyme 555 619 2.8E-13 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 Gene3D G3DSA:3.30.1490.20 120 187 1.0E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 Gene3D G3DSA:3.30.470.20 189 427 2.7E-98 T 28-03-2018 SMD44_RS18270 cd2fa3419599f178cc2de209306db731 624 SUPERFAMILY SSF51246 315 428 3.24E-33 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMD44_RS10475 8451a96193af049e5a3be2f6a5ac6c46 203 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 199 27.286 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SMD44_RS10475 8451a96193af049e5a3be2f6a5ac6c46 203 Pfam PF01121 Dephospho-CoA kinase 4 182 1.4E-56 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SMD44_RS10475 8451a96193af049e5a3be2f6a5ac6c46 203 SUPERFAMILY SSF52540 1 194 7.94E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10475 8451a96193af049e5a3be2f6a5ac6c46 203 Gene3D G3DSA:3.40.50.300 1 203 1.9E-45 T 28-03-2018 SMD44_RS10475 8451a96193af049e5a3be2f6a5ac6c46 203 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 7.3E-50 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SMD44_RS31775 5e77ab816ed2eaa20d505844f58101a5 194 Pfam PF01638 HxlR-like helix-turn-helix 53 132 1.8E-8 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS31775 5e77ab816ed2eaa20d505844f58101a5 194 Gene3D G3DSA:1.10.10.10 32 193 4.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31775 5e77ab816ed2eaa20d505844f58101a5 194 SUPERFAMILY SSF46785 40 170 1.21E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05965 1aeccbe7f030185b855a6b43a9c2694b 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 1.9E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS05965 1aeccbe7f030185b855a6b43a9c2694b 227 Gene3D G3DSA:3.40.50.2300 1 122 4.9E-36 T 28-03-2018 SMD44_RS05965 1aeccbe7f030185b855a6b43a9c2694b 227 Gene3D G3DSA:1.10.10.10 123 227 3.0E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05965 1aeccbe7f030185b855a6b43a9c2694b 227 SMART SM00862 149 225 2.7E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS05965 1aeccbe7f030185b855a6b43a9c2694b 227 SMART SM00448 2 112 4.7E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS05965 1aeccbe7f030185b855a6b43a9c2694b 227 Pfam PF00072 Response regulator receiver domain 4 112 1.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS05965 1aeccbe7f030185b855a6b43a9c2694b 227 SUPERFAMILY SSF52172 1 182 5.41E-40 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS28405 c2ae30bcc9d8023a26455496b9d091db 322 Gene3D G3DSA:3.40.50.10330 1 144 7.7E-27 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMD44_RS28405 c2ae30bcc9d8023a26455496b9d091db 322 SUPERFAMILY SSF111331 1 322 2.49E-52 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD44_RS28405 c2ae30bcc9d8023a26455496b9d091db 322 SMART SM00046 2 133 3.5E-9 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD44_RS28405 c2ae30bcc9d8023a26455496b9d091db 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 132 1.4E-26 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD44_RS05555 ff2e557d8586b86991624b4dc1dc8238 346 SUPERFAMILY SSF53901 1 204 2.69E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS05555 ff2e557d8586b86991624b4dc1dc8238 346 PIRSF PIRSF000451 1 346 8.1E-71 T 28-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 SMD44_RS05555 ff2e557d8586b86991624b4dc1dc8238 346 Gene3D G3DSA:3.40.47.10 194 346 1.1E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS05555 ff2e557d8586b86991624b4dc1dc8238 346 SUPERFAMILY SSF53901 191 344 5.07E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS05555 ff2e557d8586b86991624b4dc1dc8238 346 Gene3D G3DSA:3.40.47.10 2 193 7.9E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS05555 ff2e557d8586b86991624b4dc1dc8238 346 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 216 338 2.5E-6 T 28-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal SMD44_RS05555 ff2e557d8586b86991624b4dc1dc8238 346 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 62 204 4.9E-24 T 28-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal SMD44_RS29320 ca38155e419a1548744f452af7a2165f 244 SUPERFAMILY SSF46785 87 176 1.48E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29320 ca38155e419a1548744f452af7a2165f 244 Gene3D G3DSA:1.10.10.10 51 243 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29320 ca38155e419a1548744f452af7a2165f 244 Pfam PF13936 Helix-turn-helix domain 5 45 3.4E-13 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain SMD44_RS29320 ca38155e419a1548744f452af7a2165f 244 Pfam PF12802 MarR family 104 163 1.2E-8 T 28-03-2018 SMD44_RS29320 ca38155e419a1548744f452af7a2165f 244 Gene3D G3DSA:1.10.10.60 3 50 5.4E-9 T 28-03-2018 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 Gene3D G3DSA:3.30.70.890 213 386 2.4E-49 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 Pfam PF08544 GHMP kinases C terminal 286 366 1.5E-10 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 Gene3D G3DSA:3.30.230.10 7 212 4.6E-63 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 TIGRFAM TIGR00131 gal_kin: galactokinase 10 367 1.8E-83 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 124 135 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PRINTS PR00959 Mevalonate kinase family signature 122 144 1.5E-38 T 28-03-2018 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PRINTS PR00959 Mevalonate kinase family signature 165 184 1.5E-38 T 28-03-2018 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PRINTS PR00959 Mevalonate kinase family signature 29 53 1.5E-38 T 28-03-2018 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PRINTS PR00959 Mevalonate kinase family signature 333 350 1.5E-38 T 28-03-2018 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 SUPERFAMILY SSF54211 5 206 1.29E-61 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 Pfam PF00288 GHMP kinases N terminal domain 117 182 8.4E-16 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PIRSF PIRSF000530 1 388 3.1E-117 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 SUPERFAMILY SSF55060 210 386 1.21E-45 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PRINTS PR00473 Galactokinase signature 31 49 3.3E-20 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PRINTS PR00473 Galactokinase signature 115 133 3.3E-20 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PRINTS PR00473 Galactokinase signature 270 284 3.3E-20 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 PRINTS PR00473 Galactokinase signature 95 106 3.3E-20 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 Pfam PF10509 Galactokinase galactose-binding signature 14 61 2.7E-18 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD44_RS17025 277493103be381cbf4f0bac802e654d0 388 Hamap MF_00246 Galactokinase [galK]. 29 386 40.408 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD44_RS26555 424d300675a123ebb4f7d2aeff498739 180 SUPERFAMILY SSF89155 3 153 4.19E-30 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMD44_RS26555 424d300675a123ebb4f7d2aeff498739 180 Gene3D G3DSA:1.10.3480.10 1 169 2.2E-28 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMD44_RS26555 424d300675a123ebb4f7d2aeff498739 180 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 32 148 8.1E-27 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 SMD44_RS26555 424d300675a123ebb4f7d2aeff498739 180 Pfam PF02613 Nitrate reductase delta subunit 27 144 2.1E-15 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMD44_RS39495 a81dc0a74ef7a8dbd78b1cf56b9335df 296 Gene3D G3DSA:1.10.10.10 148 288 9.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39495 a81dc0a74ef7a8dbd78b1cf56b9335df 296 Gene3D G3DSA:1.10.260.40 21 92 1.4E-4 T 28-03-2018 SMD44_RS39495 a81dc0a74ef7a8dbd78b1cf56b9335df 296 SUPERFAMILY SSF88659 218 282 1.0E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 257 3.9E-47 T 28-03-2018 SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 Gene3D G3DSA:3.40.50.720 1 261 6.2E-57 T 28-03-2018 SMD44_RS17645 94bc9049dcceaee400209b001f174f5c 261 SUPERFAMILY SSF51735 5 260 2.19E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 SUPERFAMILY SSF51735 149 358 5.58E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 82 95 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 Gene3D G3DSA:3.40.50.10860 9 153 3.2E-50 T 28-03-2018 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 30 139 1.9E-25 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 PIRSF PIRSF000188 9 360 2.2E-143 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 SMART SM00839 152 359 4.5E-45 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 140 162 2.0E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 297 308 2.0E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 74 88 2.0E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 184 204 2.0E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 Gene3D G3DSA:3.40.50.720 154 359 6.0E-31 T 28-03-2018 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 224 356 2.7E-8 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS19930 82cf17572e61b525860001949bcf4eef 360 SUPERFAMILY SSF53223 19 152 1.89E-44 T 28-03-2018 SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 14 457 1.0E-125 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 Gene3D G3DSA:1.10.275.10 12 105 1.9E-15 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 SUPERFAMILY SSF48557 13 459 1.88E-81 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 SMART SM00998 372 458 2.2E-19 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 Gene3D G3DSA:1.10.40.30 386 457 2.2E-15 T 28-03-2018 SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 1.3E-11 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 PRINTS PR00149 Fumarate lyase superfamily signature 101 119 1.3E-11 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 1.3E-11 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 1.3E-11 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 Pfam PF10397 Adenylosuccinate lyase C-terminus 373 457 2.5E-12 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 Pfam PF00206 Lyase 64 303 6.9E-20 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal SMD44_RS05925 562d1f7d1f0372817219edf4b5170494 480 Gene3D G3DSA:1.20.200.10 106 385 4.7E-56 T 28-03-2018 SMD44_RS19105 4fc83f89c2fb530deaa40379bd943156 160 SUPERFAMILY SSF47413 8 69 2.68E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS19105 4fc83f89c2fb530deaa40379bd943156 160 Pfam PF01381 Helix-turn-helix 13 65 2.9E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS19105 4fc83f89c2fb530deaa40379bd943156 160 SMART SM00530 12 67 1.6E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS19105 4fc83f89c2fb530deaa40379bd943156 160 Gene3D G3DSA:1.10.260.40 4 118 7.8E-19 T 28-03-2018 SMD44_RS40275 ae3569373deaa2122d3b8bdc32b45eec 63 Gene3D G3DSA:1.10.10.10 1 63 5.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40275 ae3569373deaa2122d3b8bdc32b45eec 63 SUPERFAMILY SSF46785 2 57 6.55E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40275 ae3569373deaa2122d3b8bdc32b45eec 63 Pfam PF01022 Bacterial regulatory protein, arsR family 5 36 9.9E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS14725 49eae1ad0d1378baaffae9c79b684e84 291 Gene3D G3DSA:3.20.20.70 1 291 2.8E-87 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS14725 49eae1ad0d1378baaffae9c79b684e84 291 SUPERFAMILY SSF51569 23 278 1.72E-37 T 28-03-2018 SMD44_RS35965 95ee428b3027921a73516db08b9e9193 398 Gene3D G3DSA:3.90.1150.10 291 398 4.5E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS35965 95ee428b3027921a73516db08b9e9193 398 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 244 253 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD44_RS35965 95ee428b3027921a73516db08b9e9193 398 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 398 54.724 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 SMD44_RS35965 95ee428b3027921a73516db08b9e9193 398 Gene3D G3DSA:3.40.640.10 61 290 2.7E-60 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS35965 95ee428b3027921a73516db08b9e9193 398 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 6 395 1.5E-197 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 SMD44_RS35965 95ee428b3027921a73516db08b9e9193 398 Pfam PF00155 Aminotransferase class I and II 46 390 2.0E-72 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS35965 95ee428b3027921a73516db08b9e9193 398 SUPERFAMILY SSF53383 10 394 7.85E-119 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS19810 7ddc5f7d27b06b1ab4adbf0fa75795d1 376 SUPERFAMILY SSF53901 12 229 2.33E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19810 7ddc5f7d27b06b1ab4adbf0fa75795d1 376 SUPERFAMILY SSF53901 215 369 3.64E-10 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19810 7ddc5f7d27b06b1ab4adbf0fa75795d1 376 Gene3D G3DSA:3.40.47.10 246 374 3.0E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19810 7ddc5f7d27b06b1ab4adbf0fa75795d1 376 Gene3D G3DSA:3.40.47.10 15 243 1.8E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19810 7ddc5f7d27b06b1ab4adbf0fa75795d1 376 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 90 213 1.3E-8 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS14415 0700a6c8c929900280c63d17b4000757 307 SUPERFAMILY SSF103481 57 160 1.83E-8 T 28-03-2018 SMD44_RS14415 0700a6c8c929900280c63d17b4000757 307 Pfam PF00892 EamA-like transporter family 168 301 2.3E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS14415 0700a6c8c929900280c63d17b4000757 307 Pfam PF00892 EamA-like transporter family 24 156 9.5E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS14415 0700a6c8c929900280c63d17b4000757 307 SUPERFAMILY SSF103481 203 304 3.92E-15 T 28-03-2018 SMD44_RS04210 1dfe21af37ebf410d09095acb5496a3c 403 Gene3D G3DSA:1.10.260.40 4 74 7.4E-17 T 28-03-2018 SMD44_RS04210 1dfe21af37ebf410d09095acb5496a3c 403 SMART SM00530 11 66 6.5E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS04210 1dfe21af37ebf410d09095acb5496a3c 403 Pfam PF13560 Helix-turn-helix domain 8 64 1.5E-11 T 28-03-2018 SMD44_RS04210 1dfe21af37ebf410d09095acb5496a3c 403 SUPERFAMILY SSF47413 4 72 3.49E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS04210 1dfe21af37ebf410d09095acb5496a3c 403 Gene3D G3DSA:1.25.40.10 81 399 6.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34715 b4f09a2bf725cf84874f9d0b767f2840 339 Gene3D G3DSA:1.10.3470.10 58 336 2.7E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS34715 b4f09a2bf725cf84874f9d0b767f2840 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 64 330 1.0E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 ProSitePatterns PS00216 Sugar transport proteins signature 1. 328 345 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 SUPERFAMILY SSF103473 16 474 7.19E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 PRINTS PR00171 Sugar transporter signature 403 415 8.8E-24 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 PRINTS PR00171 Sugar transporter signature 284 294 8.8E-24 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 PRINTS PR00171 Sugar transporter signature 380 401 8.8E-24 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 PRINTS PR00171 Sugar transporter signature 34 44 8.8E-24 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 PRINTS PR00171 Sugar transporter signature 117 136 8.8E-24 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 21 474 1.5E-105 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 Pfam PF00083 Sugar (and other) transporter 27 474 6.5E-108 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 Gene3D G3DSA:1.20.1250.20 21 228 4.4E-34 T 28-03-2018 SMD44_RS30400 2ac471d610d2e20e242262633c9b2cac 475 Gene3D G3DSA:1.20.1250.20 250 475 3.0E-35 T 28-03-2018 SMD44_RS34410 a47248a1c2db3b0ca817e825300284f6 194 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 18 135 1.3E-14 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS34410 a47248a1c2db3b0ca817e825300284f6 194 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 175 5.5E-27 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS34410 a47248a1c2db3b0ca817e825300284f6 194 SUPERFAMILY SSF109854 6 141 2.24E-21 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS34410 a47248a1c2db3b0ca817e825300284f6 194 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 14 192 2.5E-53 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 SMD44_RS34410 a47248a1c2db3b0ca817e825300284f6 194 Gene3D G3DSA:1.20.120.450 2 142 1.6E-21 T 28-03-2018 SMD44_RS15375 d368671061ade2327c4bc4fe50cdee5f 501 Gene3D G3DSA:3.40.720.10 33 308 7.1E-48 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD44_RS15375 d368671061ade2327c4bc4fe50cdee5f 501 Gene3D G3DSA:2.60.120.260 310 501 2.3E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS15375 d368671061ade2327c4bc4fe50cdee5f 501 SUPERFAMILY SSF53649 30 290 9.55E-41 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD44_RS15375 d368671061ade2327c4bc4fe50cdee5f 501 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 41 126 3.5E-12 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SMD44_RS15375 d368671061ade2327c4bc4fe50cdee5f 501 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 168 257 1.8E-10 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SMD44_RS17100 bd31687028ea17565c9fbcd003efbdcd 544 SUPERFAMILY SSF56601 240 541 5.64E-52 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS17100 bd31687028ea17565c9fbcd003efbdcd 544 Gene3D G3DSA:3.40.710.10 215 543 6.8E-54 T 28-03-2018 SMD44_RS17100 bd31687028ea17565c9fbcd003efbdcd 544 Pfam PF00905 Penicillin binding protein transpeptidase domain 265 540 1.4E-35 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS17100 bd31687028ea17565c9fbcd003efbdcd 544 Gene3D G3DSA:3.10.450.50 35 190 2.9E-4 T 28-03-2018 SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 Gene3D G3DSA:3.20.20.80 138 578 7.8E-110 T 28-03-2018 SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 SUPERFAMILY SSF81296 5 148 2.38E-41 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 700 1.1E-291 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 Gene3D G3DSA:2.60.40.1180 579 705 2.3E-29 T 28-03-2018 SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 SUPERFAMILY SSF51011 589 701 4.46E-20 T 28-03-2018 SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 SUPERFAMILY SSF51445 134 471 2.67E-129 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 SUPERFAMILY SSF51445 500 574 2.67E-129 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 SMART SM00642 133 566 7.2E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 Pfam PF00128 Alpha amylase, catalytic domain 190 278 1.3E-5 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 Gene3D G3DSA:2.60.40.10 5 137 1.3E-44 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS39230 9b08fedcfad74302d4f94104f4134551 705 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 1.4E-16 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SMD44_RS12085 b33cdcc83f667b6c3784b7ed37fe06ce 261 SUPERFAMILY SSF55909 1 259 5.5E-48 T 28-03-2018 SMD44_RS12085 b33cdcc83f667b6c3784b7ed37fe06ce 261 Pfam PF02274 Amidinotransferase 53 259 4.8E-10 T 28-03-2018 SMD44_RS12085 b33cdcc83f667b6c3784b7ed37fe06ce 261 Gene3D G3DSA:3.75.10.10 1 259 1.6E-56 T 28-03-2018 SMD44_RS24165 4d7429e0418f79091b7152dc91ad9d8b 330 SMART SM00829 10 328 8.0E-15 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS24165 4d7429e0418f79091b7152dc91ad9d8b 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 95 1.7E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS24165 4d7429e0418f79091b7152dc91ad9d8b 330 Gene3D G3DSA:3.90.180.10 1 152 1.4E-35 T 28-03-2018 SMD44_RS24165 4d7429e0418f79091b7152dc91ad9d8b 330 Gene3D G3DSA:3.40.50.720 153 269 2.4E-20 T 28-03-2018 SMD44_RS24165 4d7429e0418f79091b7152dc91ad9d8b 330 SUPERFAMILY SSF51735 116 271 5.0E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24165 4d7429e0418f79091b7152dc91ad9d8b 330 Pfam PF13602 Zinc-binding dehydrogenase 193 328 1.8E-18 T 28-03-2018 SMD44_RS24165 4d7429e0418f79091b7152dc91ad9d8b 330 SUPERFAMILY SSF50129 1 153 1.32E-27 T 28-03-2018 IPR011032 GroES-like SMD44_RS05500 5939a62b24e868a3ca625e30a36517ea 274 Gene3D G3DSA:3.40.80.10 55 266 2.8E-38 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS05500 5939a62b24e868a3ca625e30a36517ea 274 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 90 243 1.4E-14 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS05500 5939a62b24e868a3ca625e30a36517ea 274 SMART SM00701 66 215 7.1E-52 T 28-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS05500 5939a62b24e868a3ca625e30a36517ea 274 SMART SM00644 77 243 0.0066 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS05500 5939a62b24e868a3ca625e30a36517ea 274 SUPERFAMILY SSF55846 66 257 6.02E-41 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 19 290 1.8E-69 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 PRINTS PR00146 Dihydrodipicolinate synthase signature 48 69 5.3E-28 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 PRINTS PR00146 Dihydrodipicolinate synthase signature 141 158 5.3E-28 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 PRINTS PR00146 Dihydrodipicolinate synthase signature 116 132 5.3E-28 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 PRINTS PR00146 Dihydrodipicolinate synthase signature 84 102 5.3E-28 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 PIRSF PIRSF001365 13 309 5.8E-79 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 Pfam PF00701 Dihydrodipicolinate synthetase family 15 293 6.3E-74 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 14 300 51.136 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 SMART SM01130 14 302 5.1E-105 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 51 68 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 SUPERFAMILY SSF51569 15 302 1.36E-87 T 28-03-2018 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 Gene3D G3DSA:3.20.20.70 10 314 4.1E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS09940 c4cd25ae27275b64371264174f732058 322 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 146 176 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 SMD44_RS14745 2a139f78e24d52f4f051c1d8d0625444 66 Gene3D G3DSA:1.10.1660.10 1 64 1.5E-7 T 28-03-2018 SMD44_RS14745 2a139f78e24d52f4f051c1d8d0625444 66 SUPERFAMILY SSF46955 6 57 1.1E-6 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS26855 082d38dd737b0c4198bf6a9a7d3b3513 225 Gene3D G3DSA:1.10.10.10 121 225 1.2E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26855 082d38dd737b0c4198bf6a9a7d3b3513 225 SMART SM00448 2 112 1.1E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26855 082d38dd737b0c4198bf6a9a7d3b3513 225 Pfam PF00072 Response regulator receiver domain 5 112 1.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26855 082d38dd737b0c4198bf6a9a7d3b3513 225 Gene3D G3DSA:3.40.50.2300 1 120 9.0E-37 T 28-03-2018 SMD44_RS26855 082d38dd737b0c4198bf6a9a7d3b3513 225 SMART SM00862 145 221 1.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS26855 082d38dd737b0c4198bf6a9a7d3b3513 225 SUPERFAMILY SSF52172 3 173 1.81E-40 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS26855 082d38dd737b0c4198bf6a9a7d3b3513 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 221 1.2E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 7.9E-69 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 SUPERFAMILY SSF47446 333 434 3.76E-33 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.4E-20 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 SUPERFAMILY SSF52540 42 360 1.67E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 SMART SM00382 99 303 2.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 Gene3D G3DSA:3.40.50.300 92 299 1.5E-43 T 28-03-2018 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 Pfam PF02978 Signal peptide binding domain 334 431 3.3E-30 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 450 33.136 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 432 1.4E-171 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 SMART SM00963 1 86 3.1E-33 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 Gene3D G3DSA:1.20.120.140 1 91 2.4E-28 T 28-03-2018 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 Gene3D G3DSA:1.10.260.30 333 436 3.0E-35 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMD44_RS30445 887453cf85887372f4ca0340cc4747b9 521 SMART SM00962 100 298 1.4E-106 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS27220 8a73804738c0761952b1c6c194b88f76 289 Pfam PF13365 Trypsin-like peptidase domain 73 227 1.2E-11 T 28-03-2018 SMD44_RS27220 8a73804738c0761952b1c6c194b88f76 289 SUPERFAMILY SSF50494 14 242 7.71E-15 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS27220 8a73804738c0761952b1c6c194b88f76 289 Gene3D G3DSA:2.40.10.10 124 267 2.0E-15 T 28-03-2018 SMD44_RS34680 b967345e899e158e835e6ffa5efeecdf 318 Gene3D G3DSA:3.40.190.10 91 177 1.7E-16 T 28-03-2018 SMD44_RS34680 b967345e899e158e835e6ffa5efeecdf 318 Gene3D G3DSA:1.10.10.10 1 85 5.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34680 b967345e899e158e835e6ffa5efeecdf 318 SUPERFAMILY SSF53850 93 294 7.9E-32 T 28-03-2018 SMD44_RS34680 b967345e899e158e835e6ffa5efeecdf 318 Gene3D G3DSA:3.40.190.10 178 266 3.9E-16 T 28-03-2018 SMD44_RS34680 b967345e899e158e835e6ffa5efeecdf 318 SUPERFAMILY SSF46785 2 91 1.41E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34680 b967345e899e158e835e6ffa5efeecdf 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.9E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS34680 b967345e899e158e835e6ffa5efeecdf 318 Pfam PF03466 LysR substrate binding domain 91 293 8.9E-31 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS37390 fdce91575ce275dfad2c12a7ca8b1162 346 SUPERFAMILY SSF51679 13 336 2.49E-65 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS37390 fdce91575ce275dfad2c12a7ca8b1162 346 Pfam PF00296 Luciferase-like monooxygenase 13 313 2.3E-41 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS37390 fdce91575ce275dfad2c12a7ca8b1162 346 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 14 336 1.1E-99 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 SMD44_RS37390 fdce91575ce275dfad2c12a7ca8b1162 346 Gene3D G3DSA:3.20.20.30 12 338 5.2E-69 T 28-03-2018 SMD44_RS11610 3d1b2a89357d8d16e45bf48647f16b89 321 PIRSF PIRSF005963 3 320 3.1E-117 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD44_RS11610 3d1b2a89357d8d16e45bf48647f16b89 321 Hamap MF_00206 Lipoyl synthase [lipA]. 1 313 133.125 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD44_RS11610 3d1b2a89357d8d16e45bf48647f16b89 321 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 25 61 1.0E-6 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD44_RS11610 3d1b2a89357d8d16e45bf48647f16b89 321 SMART SM00729 72 286 1.2E-11 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS11610 3d1b2a89357d8d16e45bf48647f16b89 321 Gene3D G3DSA:3.20.20.70 23 293 2.6E-20 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS11610 3d1b2a89357d8d16e45bf48647f16b89 321 SUPERFAMILY SSF102114 36 314 4.97E-59 T 28-03-2018 SMD44_RS11610 3d1b2a89357d8d16e45bf48647f16b89 321 Pfam PF04055 Radical SAM superfamily 82 240 4.3E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 SUPERFAMILY SSF140990 421 616 7.72E-73 T 28-03-2018 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 SUPERFAMILY SSF52540 161 411 2.53E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 Pfam PF01434 Peptidase family M41 402 609 2.2E-79 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 339 1.2E-44 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 120 610 1.5E-231 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 619 37.177 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 Gene3D G3DSA:3.40.50.300 143 350 1.3E-62 T 28-03-2018 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 Gene3D G3DSA:1.10.8.60 351 433 2.9E-21 T 28-03-2018 SMD44_RS23700 759c2a6f33c1093114610a4f487da545 681 SMART SM00382 203 342 6.2E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS23220 70b3be96bd70811620be2423aefd2e58 478 Gene3D G3DSA:1.20.1530.10 34 417 1.1E-142 T 28-03-2018 IPR023171 Na/H antiporter domain SMD44_RS23220 70b3be96bd70811620be2423aefd2e58 478 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 36 417 20.902 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMD44_RS23220 70b3be96bd70811620be2423aefd2e58 478 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 41 409 1.0E-102 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMD44_RS23220 70b3be96bd70811620be2423aefd2e58 478 Pfam PF06965 Na+/H+ antiporter 1 38 411 6.2E-135 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMD44_RS22935 2a6beb61e80f18990462bd8169da3a1c 339 Pfam PF05050 Methyltransferase FkbM domain 126 291 5.1E-15 T 28-03-2018 IPR006342 Methyltransferase FkbM SMD44_RS22935 2a6beb61e80f18990462bd8169da3a1c 339 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 123 263 4.3E-29 T 28-03-2018 IPR006342 Methyltransferase FkbM SMD44_RS22935 2a6beb61e80f18990462bd8169da3a1c 339 SUPERFAMILY SSF53335 86 298 9.47E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS22935 2a6beb61e80f18990462bd8169da3a1c 339 Gene3D G3DSA:3.40.50.150 107 309 2.1E-36 T 28-03-2018 SMD44_RS01535 acf4a7ea4272fd673646fdc16f566cdc 351 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 72 281 2.4E-69 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SMD44_RS01535 acf4a7ea4272fd673646fdc16f566cdc 351 Gene3D G3DSA:3.40.50.1820 14 327 2.6E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01535 acf4a7ea4272fd673646fdc16f566cdc 351 Pfam PF10503 Esterase PHB depolymerase 77 275 7.4E-43 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SMD44_RS01535 acf4a7ea4272fd673646fdc16f566cdc 351 SUPERFAMILY SSF53474 55 156 1.12E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01535 acf4a7ea4272fd673646fdc16f566cdc 351 SUPERFAMILY SSF53474 300 350 2.34E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01535 acf4a7ea4272fd673646fdc16f566cdc 351 SUPERFAMILY SSF53474 159 273 2.34E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS42070 da33fc5b01cae0c7a638c2fe2caf7900 103 SUPERFAMILY SSF53474 4 67 9.48E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS42070 da33fc5b01cae0c7a638c2fe2caf7900 103 Gene3D G3DSA:3.40.50.1820 1 73 1.7E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS33615 7a7f65f7977e8db0794699cf844671e3 327 SUPERFAMILY SSF53822 44 317 2.98E-51 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS33615 7a7f65f7977e8db0794699cf844671e3 327 Gene3D G3DSA:3.40.50.2300 36 160 3.4E-24 T 28-03-2018 SMD44_RS33615 7a7f65f7977e8db0794699cf844671e3 327 Pfam PF13407 Periplasmic binding protein domain 46 290 6.4E-41 T 28-03-2018 IPR025997 Periplasmic binding protein SMD44_RS33615 7a7f65f7977e8db0794699cf844671e3 327 Gene3D G3DSA:3.40.50.2300 161 288 3.0E-15 T 28-03-2018 SMD44_RS36115 045178e3129d1ddf095c7123c017d8eb 436 Gene3D G3DSA:3.50.50.60 204 434 1.2E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36115 045178e3129d1ddf095c7123c017d8eb 436 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 7 354 1.2E-111 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD44_RS36115 045178e3129d1ddf095c7123c017d8eb 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.1E-5 T 28-03-2018 SMD44_RS36115 045178e3129d1ddf095c7123c017d8eb 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 2.1E-5 T 28-03-2018 SMD44_RS36115 045178e3129d1ddf095c7123c017d8eb 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 206 224 2.1E-5 T 28-03-2018 SMD44_RS36115 045178e3129d1ddf095c7123c017d8eb 436 Gene3D G3DSA:3.50.50.60 4 189 8.4E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36115 045178e3129d1ddf095c7123c017d8eb 436 SUPERFAMILY SSF51905 203 353 8.65E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36115 045178e3129d1ddf095c7123c017d8eb 436 SUPERFAMILY SSF51905 4 237 2.96E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 Pfam PF00582 Universal stress protein family 8 142 7.8E-24 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 Pfam PF00582 Universal stress protein family 155 292 4.3E-22 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 Gene3D G3DSA:3.40.50.620 1 142 1.3E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 Gene3D G3DSA:3.40.50.620 150 295 1.3E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 SUPERFAMILY SSF52402 8 145 4.77E-27 T 28-03-2018 SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 PRINTS PR01438 Universal stress protein signature 102 114 3.4E-13 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 PRINTS PR01438 Universal stress protein signature 120 142 3.4E-13 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 PRINTS PR01438 Universal stress protein signature 5 23 3.4E-13 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39185 db37a9e6a088f6fc128383a495e6bc7c 295 SUPERFAMILY SSF52402 156 293 1.93E-22 T 28-03-2018 SMD44_RS08285 63a1bdd8e99f9a9d0df5fac036a66c14 584 SUPERFAMILY SSF52743 173 505 2.88E-29 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS08285 63a1bdd8e99f9a9d0df5fac036a66c14 584 PRINTS PR00723 Subtilisin serine protease family (S8) signature 438 454 2.8E-7 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS08285 63a1bdd8e99f9a9d0df5fac036a66c14 584 PRINTS PR00723 Subtilisin serine protease family (S8) signature 190 209 2.8E-7 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS08285 63a1bdd8e99f9a9d0df5fac036a66c14 584 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 239 2.8E-7 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS08285 63a1bdd8e99f9a9d0df5fac036a66c14 584 Pfam PF00082 Subtilase family 227 479 3.1E-11 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS08285 63a1bdd8e99f9a9d0df5fac036a66c14 584 Gene3D G3DSA:3.40.50.200 149 517 7.9E-27 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS08285 63a1bdd8e99f9a9d0df5fac036a66c14 584 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 439 449 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS36305 8243f5d62aaf8489da634be557d74460 329 Pfam PF12833 Helix-turn-helix domain 235 314 3.0E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS36305 8243f5d62aaf8489da634be557d74460 329 SUPERFAMILY SSF46689 264 316 4.66E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS36305 8243f5d62aaf8489da634be557d74460 329 Pfam PF14525 AraC-binding-like domain 20 193 3.0E-17 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMD44_RS36305 8243f5d62aaf8489da634be557d74460 329 Gene3D G3DSA:1.10.10.60 265 327 3.7E-15 T 28-03-2018 SMD44_RS36305 8243f5d62aaf8489da634be557d74460 329 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 297 4.0E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS36305 8243f5d62aaf8489da634be557d74460 329 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 313 4.0E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS36305 8243f5d62aaf8489da634be557d74460 329 Gene3D G3DSA:1.10.10.60 206 264 4.4E-7 T 28-03-2018 SMD44_RS36305 8243f5d62aaf8489da634be557d74460 329 SMART SM00342 228 313 3.3E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.1E-34 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.1E-34 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 1.1E-34 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.1E-34 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.1E-34 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 2.5E-137 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PIRSF PIRSF000350 1 446 1.5E-70 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 3.4E-23 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 Gene3D G3DSA:3.40.50.720 165 328 3.6E-33 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 Gene3D G3DSA:3.50.50.60 4 164 2.0E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 SUPERFAMILY SSF55424 338 459 8.25E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 321 1.8E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 1.7E-64 T 28-03-2018 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 Gene3D G3DSA:3.30.390.30 329 456 3.2E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SMD44_RS11525 fe2cfb59dcdaff97309f561909e81479 462 SUPERFAMILY SSF51905 7 366 7.69E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 SMART SM00322 59 124 2.5E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 9.4E-93 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 SUPERFAMILY SSF54814 2 105 5.49E-34 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 SUPERFAMILY SSF54821 106 205 4.32E-38 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 3.2E-37 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 Pfam PF07650 KH domain 38 109 1.1E-18 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.757 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 Gene3D G3DSA:3.30.1140.32 107 207 1.7E-36 T 28-03-2018 SMD44_RS25530 9ecc61a488928a1d20245e0202d27548 279 Gene3D G3DSA:3.30.300.20 17 106 6.4E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS01130 c409c35f5b2c88014a15cab60716acf8 203 Pfam PF01872 RibD C-terminal domain 2 183 4.9E-26 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS01130 c409c35f5b2c88014a15cab60716acf8 203 Gene3D G3DSA:3.40.430.10 2 190 1.9E-34 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS01130 c409c35f5b2c88014a15cab60716acf8 203 SUPERFAMILY SSF53597 25 184 3.53E-27 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS34395 2860c64dd451b84bd7e85d7f333d8701 495 Pfam PF00781 Diacylglycerol kinase catalytic domain 218 322 4.8E-15 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD44_RS34395 2860c64dd451b84bd7e85d7f333d8701 495 SUPERFAMILY SSF48317 15 193 1.57E-37 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS34395 2860c64dd451b84bd7e85d7f333d8701 495 SMART SM00014 75 184 1.8E-22 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS34395 2860c64dd451b84bd7e85d7f333d8701 495 SUPERFAMILY SSF111331 210 491 8.94E-44 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD44_RS34395 2860c64dd451b84bd7e85d7f333d8701 495 SMART SM00046 211 323 7.8E-7 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD44_RS34395 2860c64dd451b84bd7e85d7f333d8701 495 Gene3D G3DSA:3.40.50.10330 209 331 1.3E-17 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMD44_RS34395 2860c64dd451b84bd7e85d7f333d8701 495 Gene3D G3DSA:1.20.144.10 4 192 9.8E-29 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS34395 2860c64dd451b84bd7e85d7f333d8701 495 Pfam PF01569 PAP2 superfamily 81 189 4.1E-18 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS27610 82519b262b7e1d29592a046be9c0a1f2 406 SUPERFAMILY SSF56574 8 169 4.58E-11 T 28-03-2018 IPR023796 Serpin domain SMD44_RS27610 82519b262b7e1d29592a046be9c0a1f2 406 SUPERFAMILY SSF56574 285 393 3.14E-10 T 28-03-2018 IPR023796 Serpin domain SMD44_RS27610 82519b262b7e1d29592a046be9c0a1f2 406 Pfam PF00079 Serpin (serine protease inhibitor) 11 169 5.1E-10 T 28-03-2018 IPR023796 Serpin domain SMD44_RS27610 82519b262b7e1d29592a046be9c0a1f2 406 Pfam PF00079 Serpin (serine protease inhibitor) 300 393 2.8E-8 T 28-03-2018 IPR023796 Serpin domain SMD44_RS27610 82519b262b7e1d29592a046be9c0a1f2 406 SMART SM00093 16 393 0.0066 T 28-03-2018 IPR023796 Serpin domain SMD44_RS27610 82519b262b7e1d29592a046be9c0a1f2 406 Gene3D G3DSA:3.30.497.10 2 396 2.0E-33 T 28-03-2018 SMD44_RS05290 adfe75d462139da925915ba65fc0d094 554 Pfam PF00128 Alpha amylase, catalytic domain 42 401 1.8E-80 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS05290 adfe75d462139da925915ba65fc0d094 554 SMART SM00642 27 423 1.8E-127 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS05290 adfe75d462139da925915ba65fc0d094 554 Gene3D G3DSA:3.20.20.80 16 489 5.0E-127 T 28-03-2018 SMD44_RS05290 adfe75d462139da925915ba65fc0d094 554 Pfam PF11941 Domain of unknown function (DUF3459) 472 552 6.5E-8 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMD44_RS05290 adfe75d462139da925915ba65fc0d094 554 SUPERFAMILY SSF51445 17 486 2.52E-130 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS07070 af57386e05f5d8ad8229ee5e1df50612 301 Pfam PF00296 Luciferase-like monooxygenase 8 227 1.7E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS07070 af57386e05f5d8ad8229ee5e1df50612 301 Gene3D G3DSA:3.20.20.30 3 241 2.9E-53 T 28-03-2018 SMD44_RS07070 af57386e05f5d8ad8229ee5e1df50612 301 SUPERFAMILY SSF51679 9 283 8.1E-52 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS07070 af57386e05f5d8ad8229ee5e1df50612 301 Gene3D G3DSA:3.20.20.30 242 298 0.011 T 28-03-2018 SMD44_RS07070 af57386e05f5d8ad8229ee5e1df50612 301 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 12 274 2.7E-75 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 SMART SM00829 10 331 3.2E-10 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 SUPERFAMILY SSF51735 117 249 9.06E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 Gene3D G3DSA:3.90.180.10 262 333 0.0076 T 28-03-2018 SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 SUPERFAMILY SSF50129 1 121 1.29E-28 T 28-03-2018 IPR011032 GroES-like SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 SUPERFAMILY SSF50129 303 331 1.29E-28 T 28-03-2018 IPR011032 GroES-like SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 Pfam PF00107 Zinc-binding dehydrogenase 155 253 1.7E-17 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 93 1.7E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 Gene3D G3DSA:3.40.50.720 153 261 8.7E-15 T 28-03-2018 SMD44_RS18920 c281f63b95608e97e69b0e41e0172eb5 333 Gene3D G3DSA:3.90.180.10 1 152 5.3E-37 T 28-03-2018 SMD44_RS18295 bceef004d7638a1b89944d61274e6191 85 Gene3D G3DSA:1.10.1220.10 1 84 3.2E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS18295 bceef004d7638a1b89944d61274e6191 85 SUPERFAMILY SSF47598 1 45 1.3E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMD44_RS33785 83b05e2da22753480ef23b354c8b0912 149 Pfam PF13466 STAS domain 19 97 7.2E-13 T 28-03-2018 IPR002645 STAS domain SMD44_RS33785 83b05e2da22753480ef23b354c8b0912 149 SUPERFAMILY SSF52091 7 99 2.94E-16 T 28-03-2018 IPR002645 STAS domain SMD44_RS33785 83b05e2da22753480ef23b354c8b0912 149 Gene3D G3DSA:3.30.750.24 3 108 7.3E-13 T 28-03-2018 IPR002645 STAS domain SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 378 8.2E-132 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 404 46.889 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 Gene3D G3DSA:3.90.550.10 7 294 1.1E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 Gene3D G3DSA:2.160.10.10 295 399 1.3E-14 T 28-03-2018 SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 SUPERFAMILY SSF53448 342 358 2.82E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 SUPERFAMILY SSF53448 7 281 2.82E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 Pfam PF00483 Nucleotidyl transferase 9 277 5.4E-65 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 SUPERFAMILY SSF51161 301 391 2.91E-15 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 197 207 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SMD44_RS37035 5e1f3c82cb5be3eebdfec5b32f5ecea8 406 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SMD44_RS27010 4f7a6d5328757ca8d2b45ceb41fc7cfb 383 SUPERFAMILY SSF55781 25 181 4.42E-12 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS27010 4f7a6d5328757ca8d2b45ceb41fc7cfb 383 Gene3D G3DSA:3.30.70.270 190 354 7.0E-38 T 28-03-2018 SMD44_RS27010 4f7a6d5328757ca8d2b45ceb41fc7cfb 383 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 189 347 4.1E-25 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS27010 4f7a6d5328757ca8d2b45ceb41fc7cfb 383 Gene3D G3DSA:3.30.450.40 1 189 3.1E-24 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS27010 4f7a6d5328757ca8d2b45ceb41fc7cfb 383 Pfam PF00990 Diguanylate cyclase, GGDEF domain 191 344 1.3E-26 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS27010 4f7a6d5328757ca8d2b45ceb41fc7cfb 383 SUPERFAMILY SSF55073 196 345 2.2E-29 T 28-03-2018 IPR029787 Nucleotide cyclase SMD44_RS27010 4f7a6d5328757ca8d2b45ceb41fc7cfb 383 SMART SM00267 180 350 2.0E-45 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS19135 8e250c01e029b515a42d234eb2642e5b 159 Pfam PF12680 SnoaL-like domain 43 140 4.3E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS19135 8e250c01e029b515a42d234eb2642e5b 159 Gene3D G3DSA:3.10.450.50 19 159 9.7E-19 T 28-03-2018 SMD44_RS19135 8e250c01e029b515a42d234eb2642e5b 159 SUPERFAMILY SSF54427 19 154 2.85E-23 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS41990 82e4d688e0f902b1de5cce4df588ae24 150 Gene3D G3DSA:2.30.110.10 2 145 1.8E-23 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS41990 82e4d688e0f902b1de5cce4df588ae24 150 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 16 133 7.7E-27 T 28-03-2018 IPR019920 F420-binding domain, putative SMD44_RS41990 82e4d688e0f902b1de5cce4df588ae24 150 SUPERFAMILY SSF50475 8 135 3.25E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS41990 82e4d688e0f902b1de5cce4df588ae24 150 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 94 8.9E-13 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS27115 db7294999ae4d1abdd9e0a906384bcc8 413 Gene3D G3DSA:3.30.70.260 338 412 1.9E-8 T 28-03-2018 SMD44_RS27115 db7294999ae4d1abdd9e0a906384bcc8 413 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 34 316 1.5E-83 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS27115 db7294999ae4d1abdd9e0a906384bcc8 413 SUPERFAMILY SSF53686 17 325 4.45E-93 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS27115 db7294999ae4d1abdd9e0a906384bcc8 413 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 56 69 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SMD44_RS27115 db7294999ae4d1abdd9e0a906384bcc8 413 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 35 411 1.2E-132 T 28-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 SMD44_RS27115 db7294999ae4d1abdd9e0a906384bcc8 413 SUPERFAMILY SSF55021 335 406 2.75E-5 T 28-03-2018 SMD44_RS27115 db7294999ae4d1abdd9e0a906384bcc8 413 Gene3D G3DSA:3.40.50.1100 41 151 1.2E-30 T 28-03-2018 SMD44_RS27115 db7294999ae4d1abdd9e0a906384bcc8 413 Gene3D G3DSA:3.40.50.1100 152 322 3.1E-48 T 28-03-2018 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 SMART SM00788 3 422 6.3E-282 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 197.416 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 Gene3D G3DSA:3.40.440.10 2 149 4.2E-48 T 28-03-2018 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 Gene3D G3DSA:3.40.440.10 150 264 8.3E-31 T 28-03-2018 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 Pfam PF00709 Adenylosuccinate synthetase 5 421 2.8E-178 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 SUPERFAMILY SSF52540 3 425 8.18E-172 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 Gene3D G3DSA:3.90.170.10 265 427 1.0E-67 T 28-03-2018 SMD44_RS22670 ed4069d0bc5854adbe3896ec1cd5b8e4 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 423 1.8E-165 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD44_RS19645 1b6f33615660df6cd490d46805fb617a 324 SMART SM00382 30 211 5.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19645 1b6f33615660df6cd490d46805fb617a 324 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS19645 1b6f33615660df6cd490d46805fb617a 324 SUPERFAMILY SSF52540 5 222 5.95E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19645 1b6f33615660df6cd490d46805fb617a 324 Pfam PF00005 ABC transporter 21 162 9.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19645 1b6f33615660df6cd490d46805fb617a 324 Gene3D G3DSA:3.40.50.300 2 277 4.8E-61 T 28-03-2018 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 SUPERFAMILY SSF52777 250 489 3.65E-76 T 28-03-2018 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 Gene3D G3DSA:3.90.1170.30 2 51 9.6E-14 T 28-03-2018 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 Gene3D G3DSA:3.90.1170.30 52 141 6.0E-8 T 28-03-2018 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 Pfam PF00364 Biotin-requiring enzyme 10 81 4.5E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 SUPERFAMILY SSF47005 188 232 4.58E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 Pfam PF02817 e3 binding domain 194 228 7.2E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 261 489 1.8E-77 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 Gene3D G3DSA:3.30.559.10 245 492 9.7E-81 T 28-03-2018 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 33 62 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 SUPERFAMILY SSF51230 8 102 4.97E-27 T 28-03-2018 IPR011053 Single hybrid motif SMD44_RS21825 78088bfd9ee9fe632f89024b2213695e 492 Gene3D G3DSA:4.10.320.10 189 241 1.3E-19 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS30140 67c2d6b77a7191db5928e4f547fa02ec 522 SUPERFAMILY SSF52096 8 262 7.3E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS30140 67c2d6b77a7191db5928e4f547fa02ec 522 SUPERFAMILY SSF52096 260 522 1.8E-89 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS30140 67c2d6b77a7191db5928e4f547fa02ec 522 Gene3D G3DSA:3.90.226.10 262 519 2.2E-77 T 28-03-2018 SMD44_RS30140 67c2d6b77a7191db5928e4f547fa02ec 522 Gene3D G3DSA:3.90.226.10 3 261 9.1E-76 T 28-03-2018 SMD44_RS30140 67c2d6b77a7191db5928e4f547fa02ec 522 Pfam PF01039 Carboxyl transferase domain 35 519 8.2E-197 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMD44_RS05595 3e07a581a9e0f4394b575f06f736671d 415 Pfam PF08353 Domain of unknown function (DUF1727) 307 406 1.5E-21 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 SMD44_RS05595 3e07a581a9e0f4394b575f06f736671d 415 SUPERFAMILY SSF53623 229 282 7.46E-30 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS05595 3e07a581a9e0f4394b575f06f736671d 415 SUPERFAMILY SSF53623 54 199 7.46E-30 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS05595 3e07a581a9e0f4394b575f06f736671d 415 Pfam PF08245 Mur ligase middle domain 68 269 1.9E-12 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS05595 3e07a581a9e0f4394b575f06f736671d 415 Gene3D G3DSA:3.40.1190.10 42 285 1.4E-35 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS26880 f0284d51b2b5309fd7c3f07c0167b645 419 Gene3D G3DSA:3.30.565.10 283 407 1.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26880 f0284d51b2b5309fd7c3f07c0167b645 419 Pfam PF07730 Histidine kinase 203 267 1.1E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS26880 f0284d51b2b5309fd7c3f07c0167b645 419 SUPERFAMILY SSF55874 290 405 9.39E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28655 205a0c21fa5e7857b55263d422dfa0ee 1022 SMART SM00304 451 505 0.0016 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS28655 205a0c21fa5e7857b55263d422dfa0ee 1022 SMART SM00387 660 776 1.2E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28655 205a0c21fa5e7857b55263d422dfa0ee 1022 Pfam PF08376 Nitrate and nitrite sensing 153 411 2.8E-34 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein SMD44_RS28655 205a0c21fa5e7857b55263d422dfa0ee 1022 SUPERFAMILY SSF55874 640 773 6.42E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28655 205a0c21fa5e7857b55263d422dfa0ee 1022 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 664 774 1.5E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28655 205a0c21fa5e7857b55263d422dfa0ee 1022 Gene3D G3DSA:3.30.565.10 580 774 1.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS32265 068798ebb7345783df5019d4260e27df 598 Gene3D G3DSA:3.30.420.40 187 355 1.8E-12 T 28-03-2018 SMD44_RS32265 068798ebb7345783df5019d4260e27df 598 SUPERFAMILY SSF53067 181 370 7.41E-12 T 28-03-2018 SMD44_RS32265 068798ebb7345783df5019d4260e27df 598 Gene3D G3DSA:3.30.420.40 9 186 2.4E-6 T 28-03-2018 SMD44_RS32265 068798ebb7345783df5019d4260e27df 598 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 327 341 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 Pfam PF00425 chorismate binding enzyme 420 674 1.7E-88 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00097 Anthranilate synthase component II signature 49 58 2.5E-26 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.5E-26 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00097 Anthranilate synthase component II signature 78 89 2.5E-26 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00097 Anthranilate synthase component II signature 166 179 2.5E-26 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00097 Anthranilate synthase component II signature 122 134 2.5E-26 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 1.0E-5 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 1.0E-5 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 2.8E-12 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 2.8E-12 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 2.8E-12 T 28-03-2018 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 Pfam PF04715 Anthranilate synthase component I, N terminal region 237 367 1.6E-19 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 Gene3D G3DSA:3.60.120.10 215 684 1.5E-150 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 188 2.7E-42 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 Pfam PF00117 Glutamine amidotransferase class-I 4 186 2.5E-39 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 Gene3D G3DSA:3.40.50.880 1 192 2.2E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 323 677 6.4E-105 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 SUPERFAMILY SSF52317 1 189 2.46E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS36460 3e2ebd44b8fa48882f7a9d88f3bc3b92 696 SUPERFAMILY SSF56322 218 681 3.27E-127 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 39 451 4.3E-128 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 107 119 3.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 221 234 3.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 411 424 3.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 87 105 3.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 310 329 3.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 87 105 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 SUPERFAMILY SSF51419 58 322 1.03E-71 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 SUPERFAMILY SSF50621 298 453 2.72E-48 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 Gene3D G3DSA:3.20.20.10 66 309 2.3E-65 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 67 319 1.2E-61 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 Gene3D G3DSA:2.40.37.10 310 455 7.0E-41 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 257 411 1.8E-16 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 47 454 38.471 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01181 Diaminopimelate decarboxylase signature 105 122 2.1E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01181 Diaminopimelate decarboxylase signature 338 356 2.1E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01181 Diaminopimelate decarboxylase signature 421 443 2.1E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS05950 01d3b6ab51ad48428c62742cc47c52ab 456 PRINTS PR01181 Diaminopimelate decarboxylase signature 193 202 2.1E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD44_RS37435 fc2aac213534bc80a38945412a963937 232 Gene3D G3DSA:1.10.10.10 123 230 1.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37435 fc2aac213534bc80a38945412a963937 232 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS37435 fc2aac213534bc80a38945412a963937 232 SUPERFAMILY SSF46894 131 227 7.65E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS37435 fc2aac213534bc80a38945412a963937 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 1.4E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS37435 fc2aac213534bc80a38945412a963937 232 Gene3D G3DSA:3.40.50.2300 1 122 1.9E-34 T 28-03-2018 SMD44_RS37435 fc2aac213534bc80a38945412a963937 232 SMART SM00862 151 227 1.8E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS37435 fc2aac213534bc80a38945412a963937 232 SUPERFAMILY SSF52172 1 122 1.99E-38 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS37435 fc2aac213534bc80a38945412a963937 232 SMART SM00448 2 112 6.1E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS28615 64adca46f9ee76c6fe5403c4b5673148 138 Gene3D G3DSA:1.10.10.10 3 119 3.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28615 64adca46f9ee76c6fe5403c4b5673148 138 SUPERFAMILY SSF46785 21 127 2.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28615 64adca46f9ee76c6fe5403c4b5673148 138 Pfam PF03551 Transcriptional regulator PadR-like family 25 97 3.6E-22 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Gene3D G3DSA:3.40.50.970 918 1128 1.3E-52 T 28-03-2018 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 SMART SM00861 922 1115 2.8E-52 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1120 1268 1.7E-43 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 SUPERFAMILY SSF52518 451 859 8.83E-88 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Gene3D G3DSA:1.10.287.1150 414 496 5.6E-24 T 28-03-2018 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Gene3D G3DSA:3.30.559.10 133 384 2.3E-53 T 28-03-2018 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 151 383 4.7E-50 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 25 61 2.2E-11 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 414 1268 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Pfam PF00676 Dehydrogenase E1 component 537 860 7.3E-57 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Pfam PF02779 Transketolase, pyrimidine binding domain 921 1114 1.9E-55 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 PIRSF PIRSF000157 9 1270 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 SUPERFAMILY SSF52777 137 383 1.16E-55 T 28-03-2018 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 Gene3D G3DSA:3.40.50.970 497 858 1.7E-94 T 28-03-2018 SMD44_RS28590 9c1414297d2cbc7b2e01b856d1eeb5d3 1270 SUPERFAMILY SSF52518 911 1121 2.45E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS22835 defa4a46f53ad7798bc68bca8574e7c5 192 SUPERFAMILY SSF52980 5 186 1.5E-16 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS22835 defa4a46f53ad7798bc68bca8574e7c5 192 Gene3D G3DSA:3.90.1570.10 4 191 7.3E-30 T 28-03-2018 SMD44_RS22835 defa4a46f53ad7798bc68bca8574e7c5 192 Pfam PF05685 Putative restriction endonuclease 14 182 5.2E-24 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS14110 83bff00f3ba6c3b63326cbf10c21253e 384 Gene3D G3DSA:3.40.50.2000 207 352 7.0E-21 T 28-03-2018 SMD44_RS14110 83bff00f3ba6c3b63326cbf10c21253e 384 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 10 364 5.2E-85 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 SMD44_RS14110 83bff00f3ba6c3b63326cbf10c21253e 384 Gene3D G3DSA:3.40.50.2000 3 206 1.8E-61 T 28-03-2018 SMD44_RS14110 83bff00f3ba6c3b63326cbf10c21253e 384 SUPERFAMILY SSF53756 10 365 1.26E-92 T 28-03-2018 SMD44_RS14110 83bff00f3ba6c3b63326cbf10c21253e 384 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 36 365 1.0E-90 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 SMD44_RS03865 897749cdf6cf69e1bfa35781103b822c 250 Gene3D G3DSA:3.20.20.150 1 249 1.9E-35 T 28-03-2018 SMD44_RS03865 897749cdf6cf69e1bfa35781103b822c 250 Pfam PF01261 Xylose isomerase-like TIM barrel 26 206 2.0E-19 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS03865 897749cdf6cf69e1bfa35781103b822c 250 SUPERFAMILY SSF51658 8 232 2.9E-31 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS30250 7ecd16a956a3a87ba2396ba57d073e61 198 SUPERFAMILY SSF52016 1 187 3.73E-54 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD44_RS30250 7ecd16a956a3a87ba2396ba57d073e61 198 Pfam PF00694 Aconitase C-terminal domain 1 117 3.1E-26 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS30250 7ecd16a956a3a87ba2396ba57d073e61 198 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 39.672 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMD44_RS30250 7ecd16a956a3a87ba2396ba57d073e61 198 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 1.3E-57 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMD44_RS30250 7ecd16a956a3a87ba2396ba57d073e61 198 Gene3D G3DSA:3.20.19.10 1 168 4.3E-48 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SMART SM00028 893 926 0.45 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SMART SM00028 933 965 390.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SMART SM00028 972 1005 5.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 92 4.3E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SMART SM00862 20 93 1.2E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SUPERFAMILY SSF46894 16 93 2.55E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Gene3D G3DSA:1.25.40.10 957 1101 5.7E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SUPERFAMILY SSF48452 95 262 2.09E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SUPERFAMILY SSF48452 871 1080 1.3E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SMART SM01043 100 254 1.4E-35 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Pfam PF13424 Tetratricopeptide repeat 892 963 4.8E-8 T 28-03-2018 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Pfam PF00931 NB-ARC domain 421 599 3.9E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Gene3D G3DSA:3.40.50.300 346 547 2.7E-18 T 28-03-2018 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SMART SM00382 418 575 0.0029 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Gene3D G3DSA:1.10.150.200 842 900 8.2E-4 T 28-03-2018 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SUPERFAMILY SSF52540 346 375 5.0E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 SUPERFAMILY SSF52540 412 598 5.0E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Pfam PF03704 Bacterial transcriptional activator domain 100 254 5.2E-33 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Gene3D G3DSA:1.25.40.10 97 327 4.8E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Gene3D G3DSA:1.20.1250.10 901 956 6.0E-8 T 28-03-2018 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 Gene3D G3DSA:1.10.10.10 1 96 1.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 PRINTS PR00364 Disease resistance protein signature 500 514 1.8E-7 T 28-03-2018 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 PRINTS PR00364 Disease resistance protein signature 421 436 1.8E-7 T 28-03-2018 SMD44_RS23525 3e746453768f8dffe03a222ae7caf54a 1101 PRINTS PR00364 Disease resistance protein signature 581 595 1.8E-7 T 28-03-2018 SMD44_RS19670 01222b2dc0fd9065e53925521ce14d67 183 Gene3D G3DSA:3.40.50.1950 1 182 2.4E-21 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS19670 01222b2dc0fd9065e53925521ce14d67 183 SUPERFAMILY SSF52507 3 147 1.03E-19 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS19670 01222b2dc0fd9065e53925521ce14d67 183 Pfam PF02441 Flavoprotein 8 147 4.6E-12 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS34165 df9c8953124c557e62b3ef4758ccab98 271 Pfam PF01066 CDP-alcohol phosphatidyltransferase 21 99 2.6E-10 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD44_RS34165 df9c8953124c557e62b3ef4758ccab98 271 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 26 197 2.4E-33 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 SMD44_RS34165 df9c8953124c557e62b3ef4758ccab98 271 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 78 99 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 SUPERFAMILY SSF50370 672 808 2.16E-35 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 711 796 2.5E-18 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 109 546 3.4E-64 T 28-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 Gene3D G3DSA:1.50.10.10 59 403 4.8E-25 T 28-03-2018 SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 Gene3D G3DSA:2.80.10.50 716 757 1.5E-8 T 28-03-2018 SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 Gene3D G3DSA:2.80.10.50 510 715 1.2E-9 T 28-03-2018 SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 Gene3D G3DSA:2.80.10.50 758 809 1.2E-13 T 28-03-2018 SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 SMART SM00458 671 809 0.0011 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS02155 2214349babb53ef7f76677c64d87b327 809 SUPERFAMILY SSF48208 93 371 7.03E-16 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 Gene3D G3DSA:1.10.10.10 2 69 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 6.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 6.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 SUPERFAMILY SSF46785 4 90 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 SMART SM00895 76 195 1.8E-15 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 SUPERFAMILY SSF48008 74 199 6.8E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 SMART SM00345 8 66 1.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 Pfam PF07729 FCD domain 76 194 2.4E-22 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 66 5.3E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40385 404bb0f1efb1e0af066f207c8aeb6b76 224 Gene3D G3DSA:1.20.120.530 70 209 6.1E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS42555 a126c5ed5ad10bab66f3150bb1090156 366 SUPERFAMILY SSF55729 175 337 3.29E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS42555 a126c5ed5ad10bab66f3150bb1090156 366 Pfam PF13480 Acetyltransferase (GNAT) domain 188 321 4.4E-14 T 28-03-2018 SMD44_RS42555 a126c5ed5ad10bab66f3150bb1090156 366 Gene3D G3DSA:3.40.630.30 145 348 8.7E-16 T 28-03-2018 SMD44_RS37340 3029d1019fa734aaaa013b73bd5bfb89 270 Gene3D G3DSA:3.40.50.150 1 269 5.2E-44 T 28-03-2018 SMD44_RS37340 3029d1019fa734aaaa013b73bd5bfb89 270 SUPERFAMILY SSF53335 15 250 9.32E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS37340 3029d1019fa734aaaa013b73bd5bfb89 270 Pfam PF04672 S-adenosyl methyltransferase 6 268 3.6E-98 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS37340 3029d1019fa734aaaa013b73bd5bfb89 270 PIRSF PIRSF017393 1 270 9.1E-93 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 79 496 1.1E-39 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 SUPERFAMILY SSF47413 6 64 1.8E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 Pfam PF01381 Helix-turn-helix 13 63 1.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 Gene3D G3DSA:1.10.10.60 8 34 5.1E-13 T 28-03-2018 SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 Gene3D G3DSA:3.65.10.10 102 293 1.4E-26 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 Gene3D G3DSA:3.65.10.10 294 508 2.9E-30 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 SMART SM00530 12 67 3.6E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 SUPERFAMILY SSF55205 74 506 2.45E-93 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD44_RS32200 57e10cfa6fcc0b7d36ded86c4c54a91d 509 Gene3D G3DSA:1.10.260.40 35 101 0.0021 T 28-03-2018 SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 Gene3D G3DSA:3.40.50.300 93 196 2.5E-27 T 28-03-2018 SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 ProSitePatterns PS00856 Guanylate kinase-like signature. 51 68 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 Hamap MF_00328 Guanylate kinase [gmk]. 15 197 33.272 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 Gene3D G3DSA:3.40.50.300 29 62 2.5E-6 T 28-03-2018 SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 Gene3D G3DSA:3.30.63.10 63 92 1.8E-24 T 28-03-2018 SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 SMART SM00072 16 197 1.1E-61 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 18 194 1.4E-67 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 Gene3D G3DSA:3.40.50.300 6 28 8.8E-4 T 28-03-2018 SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 SUPERFAMILY SSF52540 14 194 1.48E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07235 8c5a55f91dfa7d680c8f691750868439 197 Pfam PF00625 Guanylate kinase 17 194 1.9E-43 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SMD44_RS27570 6e88ddb0a3430d91d38bd727db1bc7e5 93 Gene3D G3DSA:3.40.1620.10 2 38 1.1E-11 T 28-03-2018 SMD44_RS27570 6e88ddb0a3430d91d38bd727db1bc7e5 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 2 54 3.1E-11 T 28-03-2018 SMD44_RS27570 6e88ddb0a3430d91d38bd727db1bc7e5 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 64 1.8E-11 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMD44_RS27570 6e88ddb0a3430d91d38bd727db1bc7e5 93 SUPERFAMILY SSF143120 3 72 3.66E-14 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMD44_RS41785 ef6d5df0ae4677565ef7ef7c8d32c608 169 Gene3D G3DSA:3.40.630.30 5 163 3.6E-23 T 28-03-2018 SMD44_RS41785 ef6d5df0ae4677565ef7ef7c8d32c608 169 Pfam PF00583 Acetyltransferase (GNAT) family 53 139 8.5E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS41785 ef6d5df0ae4677565ef7ef7c8d32c608 169 SUPERFAMILY SSF55729 11 143 2.13E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 SUPERFAMILY SSF101353 249 446 6.54E-60 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 SMART SM00863 662 705 2.3E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 SUPERFAMILY SSF55186 561 720 2.75E-43 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 Gene3D G3DSA:3.30.930.10 1 245 5.1E-100 T 28-03-2018 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 SUPERFAMILY SSF55681 2 248 3.31E-90 T 28-03-2018 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 4.1E-18 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 SUPERFAMILY SSF50447 461 561 1.27E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.5E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 1.5E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.5E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.5E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 1.5E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 894 168.846 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 Gene3D G3DSA:3.30.980.10 562 722 9.9E-42 T 28-03-2018 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 Pfam PF01411 tRNA synthetases class II (A) 5 565 1.4E-197 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 Pfam PF02272 DHHA1 domain 744 889 4.1E-18 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SMD44_RS07345 9129554f0e44ff11ca8d3d7d0cdcbcc0 894 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 873 1.3E-261 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 ProSitePatterns PS00057 Ribosomal protein S18 signature. 40 63 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 39 88 2.0E-12 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 13 92 19.608 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 TIGRFAM TIGR00165 S18: ribosomal protein bS18 33 88 8.9E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 PRINTS PR00974 Ribosomal protein S18 family signature 57 64 2.9E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 PRINTS PR00974 Ribosomal protein S18 family signature 65 79 2.9E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 PRINTS PR00974 Ribosomal protein S18 family signature 79 89 2.9E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 PRINTS PR00974 Ribosomal protein S18 family signature 47 57 2.9E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 Pfam PF01084 Ribosomal protein S18 37 87 2.3E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 Gene3D G3DSA:4.10.640.10 8 92 1.1E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23610 b1cdcd6c31940036128797a32e0bce12 92 SUPERFAMILY SSF46911 20 89 2.09E-25 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS09680 78cba07554d018bf9c0c7faeacc0a6ad 484 SUPERFAMILY SSF53649 3 449 1.89E-100 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD44_RS09680 78cba07554d018bf9c0c7faeacc0a6ad 484 Gene3D G3DSA:3.40.720.10 1 390 9.2E-72 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD44_RS09680 78cba07554d018bf9c0c7faeacc0a6ad 484 Pfam PF00884 Sulfatase 3 359 8.1E-53 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SMD44_RS09680 78cba07554d018bf9c0c7faeacc0a6ad 484 Gene3D G3DSA:3.30.1120.10 391 454 4.2E-9 T 28-03-2018 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 Gene3D G3DSA:1.10.510.10 232 342 4.5E-9 T 28-03-2018 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 Gene3D G3DSA:3.30.200.20 85 231 5.4E-14 T 28-03-2018 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 108 132 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 Gene3D G3DSA:1.25.40.10 343 579 7.7E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 Pfam PF00069 Protein kinase domain 102 305 1.6E-16 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 Gene3D G3DSA:1.25.40.10 580 766 0.0047 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 Pfam PF16918 Protein kinase G tetratricopeptide repeat 439 766 1.8E-31 T 28-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 SUPERFAMILY SSF56112 94 308 1.31E-29 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 SMART SM00220 102 389 4.6E-10 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS17600 68d408b5b554587a94e44e0d8ecfecdb 776 SUPERFAMILY SSF48452 532 644 7.59E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28510 8df4fa485eea4daceebb594ac2380541 257 Pfam PF13649 Methyltransferase domain 53 152 1.4E-14 T 28-03-2018 SMD44_RS28510 8df4fa485eea4daceebb594ac2380541 257 SUPERFAMILY SSF53335 18 199 3.32E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS28510 8df4fa485eea4daceebb594ac2380541 257 Gene3D G3DSA:3.40.50.150 13 257 2.4E-33 T 28-03-2018 SMD44_RS12110 e2529984589d880219327f5fb565c0a1 542 SUPERFAMILY SSF56300 166 514 7.97E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS12110 e2529984589d880219327f5fb565c0a1 542 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 62 158 8.8E-30 T 28-03-2018 IPR032093 Phospholipase D, N-terminal SMD44_RS12110 e2529984589d880219327f5fb565c0a1 542 Gene3D G3DSA:3.60.21.10 165 527 5.5E-38 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS12110 e2529984589d880219327f5fb565c0a1 542 Gene3D G3DSA:2.60.40.380 59 162 0.0015 T 28-03-2018 SMD44_RS12110 e2529984589d880219327f5fb565c0a1 542 Pfam PF09423 PhoD-like phosphatase 170 511 1.7E-104 T 28-03-2018 IPR018946 Alkaline phosphatase D-related SMD44_RS12230 0188787d66814017c2a9ab0d847654a6 465 SUPERFAMILY SSF53098 4 129 1.77E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS12230 0188787d66814017c2a9ab0d847654a6 465 Pfam PF13456 Reverse transcriptase-like 8 130 2.8E-19 T 28-03-2018 SMD44_RS12230 0188787d66814017c2a9ab0d847654a6 465 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 265 460 5.4E-57 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS12230 0188787d66814017c2a9ab0d847654a6 465 Gene3D G3DSA:3.30.420.10 2 157 2.1E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS12230 0188787d66814017c2a9ab0d847654a6 465 Gene3D G3DSA:3.40.50.1240 263 465 5.8E-51 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS12230 0188787d66814017c2a9ab0d847654a6 465 SUPERFAMILY SSF53254 263 464 2.36E-52 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS12230 0188787d66814017c2a9ab0d847654a6 465 PIRSF PIRSF036922 1 465 4.1E-174 T 28-03-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing SMD44_RS12230 0188787d66814017c2a9ab0d847654a6 465 SMART SM00855 264 420 2.4E-14 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS38915 30bdc5bbbc2c36a8543b32e5eee323c2 496 Gene3D G3DSA:3.40.390.10 258 469 1.4E-7 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD44_RS38915 30bdc5bbbc2c36a8543b32e5eee323c2 496 Pfam PF13583 Metallo-peptidase family M12B Reprolysin-like 263 453 4.2E-9 T 28-03-2018 SMD44_RS38915 30bdc5bbbc2c36a8543b32e5eee323c2 496 SUPERFAMILY SSF55486 262 435 1.09E-9 T 28-03-2018 SMD44_RS41250 2ba457c8a04bf6b94f54ce392936a957 206 SUPERFAMILY SSF55821 1 203 2.38E-46 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD44_RS41250 2ba457c8a04bf6b94f54ce392936a957 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 5.0E-40 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 SMD44_RS41250 2ba457c8a04bf6b94f54ce392936a957 206 Gene3D G3DSA:3.90.870.10 1 206 2.9E-46 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD44_RS41250 2ba457c8a04bf6b94f54ce392936a957 206 Pfam PF01300 Telomere recombination 24 198 3.7E-31 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 SMD44_RS11375 2f829cb09e7b6f3a28a5dac96c0956f1 352 SUPERFAMILY SSF50022 169 351 1.62E-27 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS11375 2f829cb09e7b6f3a28a5dac96c0956f1 352 Pfam PF00355 Rieske [2Fe-2S] domain 238 323 1.9E-9 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS11375 2f829cb09e7b6f3a28a5dac96c0956f1 352 Gene3D G3DSA:2.102.10.10 192 352 4.6E-36 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS03520 788c27be9be8847d43a739a5cf57fffd 343 SUPERFAMILY SSF52540 4 37 6.07E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS03520 788c27be9be8847d43a739a5cf57fffd 343 SUPERFAMILY SSF52540 122 193 6.07E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS03520 788c27be9be8847d43a739a5cf57fffd 343 SUPERFAMILY SSF52540 238 309 6.07E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS03520 788c27be9be8847d43a739a5cf57fffd 343 Pfam PF13469 Sulfotransferase family 6 211 7.9E-12 T 28-03-2018 SMD44_RS03520 788c27be9be8847d43a739a5cf57fffd 343 Gene3D G3DSA:3.40.50.300 2 322 2.7E-28 T 28-03-2018 SMD44_RS19435 b49e235ee5dcdc1506669fb667c77b0a 404 Gene3D G3DSA:3.90.1720.10 193 336 1.4E-30 T 28-03-2018 SMD44_RS19435 b49e235ee5dcdc1506669fb667c77b0a 404 SUPERFAMILY SSF53955 49 186 7.5E-33 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS19435 b49e235ee5dcdc1506669fb667c77b0a 404 Gene3D G3DSA:1.10.530.10 42 192 3.2E-36 T 28-03-2018 SMD44_RS19435 b49e235ee5dcdc1506669fb667c77b0a 404 Pfam PF01464 Transglycosylase SLT domain 66 169 8.2E-16 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SMD44_RS19435 b49e235ee5dcdc1506669fb667c77b0a 404 SUPERFAMILY SSF54001 195 322 5.89E-34 T 28-03-2018 SMD44_RS19435 b49e235ee5dcdc1506669fb667c77b0a 404 Pfam PF00877 NlpC/P60 family 213 313 2.2E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS36300 a07efe9bb09f6c8de2fed4fe38d98ce5 357 SUPERFAMILY SSF82689 243 341 4.32E-16 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SMD44_RS36300 a07efe9bb09f6c8de2fed4fe38d98ce5 357 SUPERFAMILY SSF82861 86 167 1.1E-11 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SMD44_RS36300 a07efe9bb09f6c8de2fed4fe38d98ce5 357 SUPERFAMILY SSF50182 168 235 1.63E-14 T 28-03-2018 IPR010920 LSM domain SMD44_RS36300 a07efe9bb09f6c8de2fed4fe38d98ce5 357 Gene3D G3DSA:2.30.30.60 186 236 1.0E-13 T 28-03-2018 SMD44_RS36300 a07efe9bb09f6c8de2fed4fe38d98ce5 357 Pfam PF00924 Mechanosensitive ion channel 126 328 3.0E-45 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMD44_RS36300 a07efe9bb09f6c8de2fed4fe38d98ce5 357 Gene3D G3DSA:3.30.70.100 237 335 2.9E-12 T 28-03-2018 SMD44_RS28775 d5a73bfb77953d266e7c465f8c27e4f8 197 Gene3D G3DSA:3.30.420.10 1 193 1.9E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS28775 d5a73bfb77953d266e7c465f8c27e4f8 197 Pfam PF00929 Exonuclease 5 177 3.9E-13 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS28775 d5a73bfb77953d266e7c465f8c27e4f8 197 SMART SM00479 3 191 1.6E-6 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS28775 d5a73bfb77953d266e7c465f8c27e4f8 197 SUPERFAMILY SSF53098 1 193 2.05E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS09685 604883844ca7a182eb2c65d143b9bade 362 SUPERFAMILY SSF51556 51 325 3.57E-59 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS09685 604883844ca7a182eb2c65d143b9bade 362 Pfam PF01979 Amidohydrolase family 48 361 4.1E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS09685 604883844ca7a182eb2c65d143b9bade 362 Gene3D G3DSA:3.20.20.140 66 323 9.4E-31 T 28-03-2018 SMD44_RS09685 604883844ca7a182eb2c65d143b9bade 362 Gene3D G3DSA:2.30.40.10 5 65 7.8E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS30795 29b7786a8a2026967cd06d598344c94d 384 Pfam PF04551 GcpE protein 22 361 2.1E-133 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS30795 29b7786a8a2026967cd06d598344c94d 384 SUPERFAMILY SSF51717 45 219 7.85E-9 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS30795 29b7786a8a2026967cd06d598344c94d 384 SUPERFAMILY SSF56014 275 359 2.62E-11 T 28-03-2018 SMD44_RS30795 29b7786a8a2026967cd06d598344c94d 384 Gene3D G3DSA:3.20.20.120 26 156 1.7E-16 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS30795 29b7786a8a2026967cd06d598344c94d 384 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 7.5E-127 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS30795 29b7786a8a2026967cd06d598344c94d 384 Gene3D G3DSA:3.20.20.120 158 381 0.063 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS30795 29b7786a8a2026967cd06d598344c94d 384 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.349 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS30795 29b7786a8a2026967cd06d598344c94d 384 PIRSF PIRSF004640 11 373 1.1E-144 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS15030 b201571fc63f973f0b3cce5eb81aa37b 200 Gene3D G3DSA:3.30.420.10 1 178 2.6E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS15030 b201571fc63f973f0b3cce5eb81aa37b 200 Pfam PF00929 Exonuclease 6 168 4.6E-26 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS15030 b201571fc63f973f0b3cce5eb81aa37b 200 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 38.051 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 SMD44_RS15030 b201571fc63f973f0b3cce5eb81aa37b 200 SMART SM00479 4 178 2.0E-26 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS15030 b201571fc63f973f0b3cce5eb81aa37b 200 SUPERFAMILY SSF53098 3 177 8.35E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 Gene3D G3DSA:3.40.50.200 215 530 8.1E-92 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 257 268 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 PIRSF PIRSF037854 20 1134 0.0 T 28-03-2018 IPR017297 Peptidase S8A, DPH-A SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 Pfam PF00082 Subtilase family 252 516 1.8E-60 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 PRINTS PR00723 Subtilisin serine protease family (S8) signature 252 271 1.2E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 PRINTS PR00723 Subtilisin serine protease family (S8) signature 289 302 1.2E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 PRINTS PR00723 Subtilisin serine protease family (S8) signature 467 483 1.2E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 293 303 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 468 478 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 SUPERFAMILY SSF52743 235 525 4.71E-86 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 Gene3D G3DSA:2.60.40.650 1035 1131 5.8E-4 T 28-03-2018 SMD44_RS34485 9b40711d63e2db72c6b2fb66e4f32a3e 1134 Gene3D G3DSA:2.60.40.10 531 646 2.0E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS06435 bf6ae379ccc705dc70289a72db92a470 204 SUPERFAMILY SSF48498 111 188 4.63E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS06435 bf6ae379ccc705dc70289a72db92a470 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 8.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06435 bf6ae379ccc705dc70289a72db92a470 204 Gene3D G3DSA:1.10.260.40 36 62 4.8E-5 T 28-03-2018 SMD44_RS06435 bf6ae379ccc705dc70289a72db92a470 204 Gene3D G3DSA:1.10.357.10 63 201 3.6E-11 T 28-03-2018 SMD44_RS06435 bf6ae379ccc705dc70289a72db92a470 204 Gene3D G3DSA:1.10.10.60 1 35 1.0E-7 T 28-03-2018 SMD44_RS06435 bf6ae379ccc705dc70289a72db92a470 204 SUPERFAMILY SSF46689 1 72 1.85E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS22255 ebf7232c962e3873a08a9bd20a676ac4 198 Gene3D G3DSA:1.10.357.10 4 198 6.9E-30 T 28-03-2018 SMD44_RS22255 ebf7232c962e3873a08a9bd20a676ac4 198 SUPERFAMILY SSF48498 82 196 1.26E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS22255 ebf7232c962e3873a08a9bd20a676ac4 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 5.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS22255 ebf7232c962e3873a08a9bd20a676ac4 198 SUPERFAMILY SSF46689 2 81 3.54E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS22255 ebf7232c962e3873a08a9bd20a676ac4 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS22255 ebf7232c962e3873a08a9bd20a676ac4 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.9E-27 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 2.9E-27 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 2.9E-27 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.9E-27 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 SMART SM00840 341 403 1.3E-15 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 311 8.4E-120 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 Gene3D G3DSA:1.20.120.640 304 393 4.9E-19 T 28-03-2018 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 SUPERFAMILY SSF47323 333 464 9.29E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 Gene3D G3DSA:3.40.50.620 1 303 6.5E-85 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 35.458 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 Pfam PF09190 DALR domain 341 394 3.3E-10 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 463 2.1E-138 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SMD44_RS18990 c9a6ee87d0f1ea043525d902668b679a 467 SUPERFAMILY SSF52374 4 310 2.06E-88 T 28-03-2018 SMD44_RS13760 d5569b510a75ad3f146ba3e205dd6888 301 SUPERFAMILY SSF56281 5 297 4.59E-58 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS13760 d5569b510a75ad3f146ba3e205dd6888 301 Pfam PF12706 Beta-lactamase superfamily domain 34 263 1.9E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS13760 d5569b510a75ad3f146ba3e205dd6888 301 Hamap MF_01818 Ribonuclease BN [rbn]. 4 297 29.482 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 SMD44_RS13760 d5569b510a75ad3f146ba3e205dd6888 301 Gene3D G3DSA:3.60.15.10 5 301 2.7E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS07075 e9d44344e5cc508680967b92dabf618f 565 SUPERFAMILY SSF54373 363 478 6.54E-27 T 28-03-2018 SMD44_RS07075 e9d44344e5cc508680967b92dabf618f 565 Pfam PF01593 Flavin containing amine oxidoreductase 58 534 5.3E-45 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS07075 e9d44344e5cc508680967b92dabf618f 565 Gene3D G3DSA:3.90.660.10 71 456 3.0E-45 T 28-03-2018 SMD44_RS07075 e9d44344e5cc508680967b92dabf618f 565 SUPERFAMILY SSF51905 500 541 5.0E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS07075 e9d44344e5cc508680967b92dabf618f 565 SUPERFAMILY SSF51905 48 378 5.0E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS07075 e9d44344e5cc508680967b92dabf618f 565 Gene3D G3DSA:3.50.50.60 459 564 6.4E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 Gene3D G3DSA:1.20.1110.10 57 341 4.6E-25 T 28-03-2018 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 Gene3D G3DSA:3.40.1110.10 342 509 4.2E-23 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 334 340 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 Pfam PF00122 E1-E2 ATPase 140 310 1.5E-31 T 28-03-2018 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 36 717 39.536 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 SUPERFAMILY SSF81660 343 488 2.09E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 Pfam PF00702 haloacid dehalogenase-like hydrolase 328 567 1.8E-31 T 28-03-2018 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 SUPERFAMILY SSF81653 140 234 6.02E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 143 370 3.6E-28 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 474 632 2.5E-40 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 500 510 5.7E-25 T 28-03-2018 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 588 5.7E-25 T 28-03-2018 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 572 5.7E-25 T 28-03-2018 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 332 346 5.7E-25 T 28-03-2018 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 181 195 5.7E-25 T 28-03-2018 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 SUPERFAMILY SSF81665 60 124 1.7E-9 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 SUPERFAMILY SSF81665 235 326 1.7E-9 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 37 713 1.7E-295 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 SUPERFAMILY SSF56784 472 596 1.93E-38 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 SUPERFAMILY SSF56784 400 430 1.93E-38 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 SUPERFAMILY SSF56784 320 344 1.93E-38 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS05970 60b5681be578b2afff045a5a5b27ef36 720 Gene3D G3DSA:1.20.1110.10 510 720 3.4E-31 T 28-03-2018 SMD44_RS14310 a0d8fe02c740c2c9bee86d2e981c5ac8 184 SUPERFAMILY SSF88659 115 179 2.06E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS14310 a0d8fe02c740c2c9bee86d2e981c5ac8 184 Pfam PF04542 Sigma-70 region 2 43 94 1.8E-4 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS14310 a0d8fe02c740c2c9bee86d2e981c5ac8 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 47 178 1.6E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS14310 a0d8fe02c740c2c9bee86d2e981c5ac8 184 SUPERFAMILY SSF88946 31 106 6.67E-8 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS14310 a0d8fe02c740c2c9bee86d2e981c5ac8 184 Gene3D G3DSA:1.10.10.10 98 181 2.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14310 a0d8fe02c740c2c9bee86d2e981c5ac8 184 Pfam PF04545 Sigma-70, region 4 128 175 5.7E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS14310 a0d8fe02c740c2c9bee86d2e981c5ac8 184 Gene3D G3DSA:1.10.1740.10 20 97 7.3E-9 T 28-03-2018 SMD44_RS11605 fddc90f3655ba1b9b7e0bea1aff4626b 283 Hamap MF_00013 Octanoyltransferase [lipB]. 3 253 32.49 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD44_RS11605 fddc90f3655ba1b9b7e0bea1aff4626b 283 PIRSF PIRSF016262 4 262 3.4E-58 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD44_RS11605 fddc90f3655ba1b9b7e0bea1aff4626b 283 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 SMD44_RS11605 fddc90f3655ba1b9b7e0bea1aff4626b 283 SUPERFAMILY SSF55681 14 132 1.41E-60 T 28-03-2018 SMD44_RS11605 fddc90f3655ba1b9b7e0bea1aff4626b 283 SUPERFAMILY SSF55681 178 251 1.41E-60 T 28-03-2018 SMD44_RS11605 fddc90f3655ba1b9b7e0bea1aff4626b 283 Gene3D G3DSA:3.30.930.10 11 251 1.2E-72 T 28-03-2018 SMD44_RS11605 fddc90f3655ba1b9b7e0bea1aff4626b 283 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 129 3.0E-23 T 28-03-2018 SMD44_RS01595 d7d8aceaefa097ca509087eca1b227f5 386 Pfam PF05787 Bacterial protein of unknown function (DUF839) 149 240 2.8E-13 T 28-03-2018 IPR008557 Protein of unknown function DUF839 SMD44_RS01595 d7d8aceaefa097ca509087eca1b227f5 386 Pfam PF05787 Bacterial protein of unknown function (DUF839) 104 147 1.4E-8 T 28-03-2018 IPR008557 Protein of unknown function DUF839 SMD44_RS01595 d7d8aceaefa097ca509087eca1b227f5 386 Gene3D G3DSA:2.130.10.120 339 370 0.039 T 28-03-2018 SMD44_RS01595 d7d8aceaefa097ca509087eca1b227f5 386 SUPERFAMILY SSF63825 175 208 1.31E-12 T 28-03-2018 SMD44_RS01595 d7d8aceaefa097ca509087eca1b227f5 386 SUPERFAMILY SSF63825 251 366 1.31E-12 T 28-03-2018 SMD44_RS01595 d7d8aceaefa097ca509087eca1b227f5 386 Pfam PF07676 WD40-like Beta Propeller Repeat 344 372 1.8E-7 T 28-03-2018 IPR011659 WD40-like Beta Propeller SMD44_RS01595 d7d8aceaefa097ca509087eca1b227f5 386 Gene3D G3DSA:2.120.10.30 150 338 2.0E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 Gene3D G3DSA:3.40.50.300 677 900 1.1E-16 T 28-03-2018 SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 Pfam PF08751 TrwC relaxase 106 572 1.0E-41 T 28-03-2018 IPR014862 TrwC relaxase SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 Gene3D G3DSA:1.10.260.40 176 253 0.073 T 28-03-2018 SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 Pfam PF13604 AAA domain 722 908 1.9E-42 T 28-03-2018 SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 SUPERFAMILY SSF52540 718 857 3.68E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 SUPERFAMILY SSF52540 830 892 4.78E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 SUPERFAMILY SSF52540 936 1102 4.78E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 SUPERFAMILY SSF55464 106 170 2.2E-42 T 28-03-2018 SMD44_RS43790 bbbf76cd1a68c86e7944f8ddc2a984d6 1478 SUPERFAMILY SSF55464 346 579 2.2E-42 T 28-03-2018 SMD44_RS16435 fc3f5583422b0ed81a724aa63196ea28 167 Pfam PF05995 Cysteine dioxygenase type I 18 151 8.8E-25 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SMD44_RS16435 fc3f5583422b0ed81a724aa63196ea28 167 SUPERFAMILY SSF51182 19 149 2.04E-33 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS16435 fc3f5583422b0ed81a724aa63196ea28 167 Gene3D G3DSA:2.60.120.10 10 162 2.8E-36 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 202 221 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 252 273 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 141 153 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 355 373 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 298 313 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 231 252 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 402 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 24 49 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 173 191 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 341 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 433 454 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 71 94 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 98 122 1.2E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 254 308 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 25 529 1.5E-209 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 33 477 3.6E-143 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 Gene3D G3DSA:1.20.210.10 20 533 6.6E-194 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS08975 7b6b5a9ffd5dfd5951494d3355bcd6e6 562 SUPERFAMILY SSF81442 21 532 3.92E-174 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS24170 3245f365df72caba696f6d5dcaf2dd42 302 Gene3D G3DSA:3.40.50.720 5 165 4.4E-27 T 28-03-2018 SMD44_RS24170 3245f365df72caba696f6d5dcaf2dd42 302 Gene3D G3DSA:1.10.1040.10 167 297 4.6E-12 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS24170 3245f365df72caba696f6d5dcaf2dd42 302 PIRSF PIRSF000103 5 301 2.4E-37 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS24170 3245f365df72caba696f6d5dcaf2dd42 302 SUPERFAMILY SSF51735 13 163 4.53E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24170 3245f365df72caba696f6d5dcaf2dd42 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 13 161 1.0E-24 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS35590 dd77e9915e6d659fff6c0872d9bb19ac 203 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 85 194 1.4E-24 T 28-03-2018 SMD44_RS35590 dd77e9915e6d659fff6c0872d9bb19ac 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 7.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35590 dd77e9915e6d659fff6c0872d9bb19ac 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 7.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35590 dd77e9915e6d659fff6c0872d9bb19ac 203 SUPERFAMILY SSF46689 5 84 2.1E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS35590 dd77e9915e6d659fff6c0872d9bb19ac 203 SUPERFAMILY SSF48498 82 193 7.59E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS35590 dd77e9915e6d659fff6c0872d9bb19ac 203 Gene3D G3DSA:1.10.10.60 2 62 5.0E-14 T 28-03-2018 SMD44_RS35590 dd77e9915e6d659fff6c0872d9bb19ac 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 5.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35590 dd77e9915e6d659fff6c0872d9bb19ac 203 Gene3D G3DSA:1.10.357.10 63 199 2.3E-20 T 28-03-2018 SMD44_RS05455 207c4403dfb1c9151b5f11a7b6fe9bc8 321 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 62 311 2.4E-61 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD44_RS05455 207c4403dfb1c9151b5f11a7b6fe9bc8 321 SUPERFAMILY SSF51197 53 321 5.49E-86 T 28-03-2018 SMD44_RS05455 207c4403dfb1c9151b5f11a7b6fe9bc8 321 Gene3D G3DSA:3.60.130.10 49 321 7.1E-70 T 28-03-2018 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 396 411 5.5E-24 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 329 345 5.5E-24 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 422 435 5.5E-24 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 290 307 5.5E-24 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 Gene3D G3DSA:2.30.40.10 62 141 4.3E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 SUPERFAMILY SSF51556 127 427 1.42E-141 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 SUPERFAMILY SSF51556 476 560 1.42E-141 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 ProSitePatterns PS01120 Urease nickel ligands signature. 125 138 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 117 6.5E-36 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 Hamap MF_01953 Urease subunit alpha [ureC]. 1 560 45.823 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 Gene3D G3DSA:3.20.20.140 142 416 8.5E-114 T 28-03-2018 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 Gene3D G3DSA:3.20.20.140 417 547 1.9E-29 T 28-03-2018 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 Pfam PF01979 Amidohydrolase family 123 445 1.4E-43 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 SUPERFAMILY SSF51338 2 127 7.78E-40 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS30045 883d33315d9db74a5987cc379bf0ae74 560 SUPERFAMILY SSF51338 417 463 7.78E-40 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 Gene3D G3DSA:3.90.640.10 174 245 3.2E-28 T 28-03-2018 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 Gene3D G3DSA:3.30.420.40 246 310 3.7E-9 T 28-03-2018 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 328 2.9E-138 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 Gene3D G3DSA:3.30.420.40 1 156 1.2E-40 T 28-03-2018 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 SUPERFAMILY SSF53067 138 323 6.48E-46 T 28-03-2018 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 SUPERFAMILY SSF53067 2 136 1.58E-37 T 28-03-2018 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 Pfam PF06723 MreB/Mbl protein 2 328 7.6E-137 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 293 319 6.4E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 38 56 6.4E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 120 139 6.4E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 58 81 6.4E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS14085 4876a01f2b70603f4533ade83cf7e9a2 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 175 195 6.4E-56 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMD44_RS18245 284a02569614f48dd9229a2353197549 215 Gene3D G3DSA:2.30.110.10 5 215 1.7E-72 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS18245 284a02569614f48dd9229a2353197549 215 PIRSF PIRSF000190 1 215 2.9E-80 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS18245 284a02569614f48dd9229a2353197549 215 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 2 215 2.1E-78 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS18245 284a02569614f48dd9229a2353197549 215 SUPERFAMILY SSF50475 12 215 1.89E-65 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS18245 284a02569614f48dd9229a2353197549 215 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 4 215 38.872 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS18245 284a02569614f48dd9229a2353197549 215 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 183 196 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS18245 284a02569614f48dd9229a2353197549 215 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 173 215 1.0E-19 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS18245 284a02569614f48dd9229a2353197549 215 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 40 119 2.9E-24 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS35055 b323e3fdeb98490f3ac2cae0ea494d84 306 SMART SM00829 11 302 8.9E-30 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS35055 b323e3fdeb98490f3ac2cae0ea494d84 306 SUPERFAMILY SSF51735 116 301 2.85E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35055 b323e3fdeb98490f3ac2cae0ea494d84 306 Pfam PF13602 Zinc-binding dehydrogenase 185 302 1.4E-17 T 28-03-2018 SMD44_RS35055 b323e3fdeb98490f3ac2cae0ea494d84 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 9.4E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS35055 b323e3fdeb98490f3ac2cae0ea494d84 306 Gene3D G3DSA:3.90.180.10 1 138 5.1E-40 T 28-03-2018 SMD44_RS35055 b323e3fdeb98490f3ac2cae0ea494d84 306 Gene3D G3DSA:3.90.180.10 231 306 3.4E-8 T 28-03-2018 SMD44_RS35055 b323e3fdeb98490f3ac2cae0ea494d84 306 SUPERFAMILY SSF50129 3 150 9.59E-37 T 28-03-2018 IPR011032 GroES-like SMD44_RS35055 b323e3fdeb98490f3ac2cae0ea494d84 306 Gene3D G3DSA:3.40.50.720 139 230 4.7E-20 T 28-03-2018 SMD44_RS07980 acd15d188e02f971f9ff4c574ff6da47 454 SUPERFAMILY SSF55931 122 452 1.18E-101 T 28-03-2018 SMD44_RS07980 acd15d188e02f971f9ff4c574ff6da47 454 Pfam PF00120 Glutamine synthetase, catalytic domain 122 449 3.7E-102 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS07980 acd15d188e02f971f9ff4c574ff6da47 454 SMART SM01230 120 372 1.0E-100 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS07980 acd15d188e02f971f9ff4c574ff6da47 454 Gene3D G3DSA:3.30.590.10 120 454 9.5E-103 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD44_RS07980 acd15d188e02f971f9ff4c574ff6da47 454 Gene3D G3DSA:3.10.20.70 7 119 2.0E-23 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS07980 acd15d188e02f971f9ff4c574ff6da47 454 SUPERFAMILY SSF54368 10 119 8.37E-17 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 SMART SM00421 158 220 1.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 SUPERFAMILY SSF52172 12 175 4.57E-18 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 Gene3D G3DSA:1.10.10.10 144 224 6.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 Gene3D G3DSA:3.40.50.2300 11 143 8.2E-26 T 28-03-2018 SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 SMART SM00448 12 132 9.9E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 Pfam PF00072 Response regulator receiver domain 14 120 7.5E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS15285 095df4a4cd3f4bacd6400231ee77cccc 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 205 1.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SMART SM00028 413 446 21.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SMART SM00028 126 159 14.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SMART SM00028 247 280 340.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SMART SM00028 373 406 2.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 Gene3D G3DSA:1.25.40.10 81 228 4.2E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 Gene3D G3DSA:1.25.40.10 229 281 0.0077 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 Gene3D G3DSA:1.10.260.40 31 79 1.3E-11 T 28-03-2018 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 Gene3D G3DSA:1.25.40.10 348 454 4.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 Gene3D G3DSA:1.10.10.60 9 30 1.6E-4 T 28-03-2018 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SUPERFAMILY SSF48452 126 155 1.88E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SUPERFAMILY SSF48452 289 320 1.88E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SUPERFAMILY SSF48452 202 240 1.88E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SUPERFAMILY SSF48452 373 440 1.88E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 Pfam PF13432 Tetratricopeptide repeat 332 400 0.0029 T 28-03-2018 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SMART SM00530 20 74 5.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 Pfam PF13560 Helix-turn-helix domain 16 73 3.6E-9 T 28-03-2018 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 Gene3D G3DSA:1.25.40.10 282 347 4.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40285 6f9b10cfcf9e419f592f43d2a63f10fc 460 SUPERFAMILY SSF47413 15 77 9.85E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS13630 7c013f062cebe4fc29f612b6ae8e303b 648 Pfam PF02449 Beta-galactosidase 37 406 4.8E-148 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS13630 7c013f062cebe4fc29f612b6ae8e303b 648 SUPERFAMILY SSF51445 31 389 1.14E-113 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS13630 7c013f062cebe4fc29f612b6ae8e303b 648 PIRSF PIRSF001084 24 647 1.5E-236 T 28-03-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS13630 7c013f062cebe4fc29f612b6ae8e303b 648 SUPERFAMILY SSF52317 417 603 1.16E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS13630 7c013f062cebe4fc29f612b6ae8e303b 648 Pfam PF08532 Beta-galactosidase trimerisation domain 419 603 4.5E-50 T 28-03-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS13630 7c013f062cebe4fc29f612b6ae8e303b 648 Gene3D G3DSA:3.20.20.80 30 398 3.7E-93 T 28-03-2018 SMD44_RS13630 7c013f062cebe4fc29f612b6ae8e303b 648 Gene3D G3DSA:3.40.50.880 416 608 3.9E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS09085 e4fd8352324d1e49b520aefd7bbe3eec 249 Pfam PF10127 Predicted nucleotidyltransferase 6 243 9.2E-57 T 28-03-2018 IPR018775 Nucleotidyltransferase, predicted SMD44_RS22305 30976222a16ea4ac546d5b8cbfccd7d2 309 Pfam PF14339 Domain of unknown function (DUF4394) 70 303 2.4E-68 T 28-03-2018 IPR025507 Domain of unknown function DUF4394 SMD44_RS18000 2ca32e76bfa7c87d2c3234a4c342fb38 275 SUPERFAMILY SSF52096 13 275 3.77E-80 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS18000 2ca32e76bfa7c87d2c3234a4c342fb38 275 Gene3D G3DSA:1.10.12.10 233 275 4.6E-17 T 28-03-2018 IPR014748 Crontonase, C-terminal SMD44_RS18000 2ca32e76bfa7c87d2c3234a4c342fb38 275 Gene3D G3DSA:3.90.226.10 15 232 1.5E-62 T 28-03-2018 SMD44_RS18000 2ca32e76bfa7c87d2c3234a4c342fb38 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 274 1.2E-59 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS36130 c0d2b58bb20bc36f01ae28a6c393f21d 303 Pfam PF00696 Amino acid kinase family 30 272 2.2E-44 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMD44_RS36130 c0d2b58bb20bc36f01ae28a6c393f21d 303 Gene3D G3DSA:3.40.1160.10 1 299 6.9E-67 T 28-03-2018 SMD44_RS36130 c0d2b58bb20bc36f01ae28a6c393f21d 303 SUPERFAMILY SSF53633 13 297 2.83E-80 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMD44_RS36130 c0d2b58bb20bc36f01ae28a6c393f21d 303 TIGRFAM TIGR00761 argB: acetylglutamate kinase 32 270 2.1E-68 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS36130 c0d2b58bb20bc36f01ae28a6c393f21d 303 Hamap MF_00082_B Acetylglutamate kinase [argB]. 28 296 32.342 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS36130 c0d2b58bb20bc36f01ae28a6c393f21d 303 PIRSF PIRSF000728 13 295 1.8E-93 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 Gene3D G3DSA:3.40.50.300 209 454 2.4E-19 T 28-03-2018 SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 SMART SM00382 235 419 3.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 SUPERFAMILY SSF52540 489 526 9.56E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 SUPERFAMILY SSF52540 215 447 9.56E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 Gene3D G3DSA:3.30.230.10 2 185 1.0E-43 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 Pfam PF01078 Magnesium chelatase, subunit ChlI 215 422 4.6E-83 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 141 1.2E-37 T 28-03-2018 SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 SUPERFAMILY SSF54211 2 170 4.93E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS30535 99083596f474fb26b8582ff39732a884 541 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 430 526 2.1E-21 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain SMD44_RS28450 5f2522f51a0e1c95c5feec67153bcb31 468 Pfam PF00027 Cyclic nucleotide-binding domain 114 201 1.3E-16 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS28450 5f2522f51a0e1c95c5feec67153bcb31 468 SUPERFAMILY SSF51206 79 213 3.01E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SMD44_RS28450 5f2522f51a0e1c95c5feec67153bcb31 468 SMART SM00100 94 217 1.8E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS28450 5f2522f51a0e1c95c5feec67153bcb31 468 Gene3D G3DSA:2.60.120.10 76 225 6.9E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS01650 04a56c0026ea011ec13209a08f64bb16 319 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 272 290 9.9E-8 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS01650 04a56c0026ea011ec13209a08f64bb16 319 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 169 191 9.9E-8 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS01650 04a56c0026ea011ec13209a08f64bb16 319 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 232 249 9.9E-8 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS01650 04a56c0026ea011ec13209a08f64bb16 319 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 38 55 9.9E-8 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS01650 04a56c0026ea011ec13209a08f64bb16 319 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 37 289 4.3E-57 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region SMD44_RS01650 04a56c0026ea011ec13209a08f64bb16 319 SUPERFAMILY SSF63829 25 302 6.38E-63 T 28-03-2018 SMD44_RS01650 04a56c0026ea011ec13209a08f64bb16 319 Gene3D G3DSA:2.120.10.30 21 306 4.9E-38 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 295 2.5E-28 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 SUPERFAMILY SSF52151 188 299 2.04E-50 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 SUPERFAMILY SSF52151 4 123 2.04E-50 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 SUPERFAMILY SSF55048 120 187 1.01E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 Gene3D G3DSA:3.40.366.10 2 133 5.0E-32 T 28-03-2018 SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 Gene3D G3DSA:3.30.70.250 134 178 6.2E-17 T 28-03-2018 SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 Gene3D G3DSA:3.40.366.10 179 306 9.8E-19 T 28-03-2018 SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 Pfam PF00698 Acyl transferase domain 6 250 6.2E-31 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 PIRSF PIRSF000446 1 258 2.2E-66 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SMD44_RS00205 0cb8c7669ba761e565f25cbd811af093 308 PIRSF PIRSF000446 273 306 8.0 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SMD44_RS02485 ca5f62e665c93f94f12c49a0e7d9fa5a 310 Gene3D G3DSA:1.10.1660.10 63 137 7.4E-5 T 28-03-2018 SMD44_RS02485 ca5f62e665c93f94f12c49a0e7d9fa5a 310 SMART SM00422 7 76 5.7E-25 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02485 ca5f62e665c93f94f12c49a0e7d9fa5a 310 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 9.2E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02485 ca5f62e665c93f94f12c49a0e7d9fa5a 310 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 9.2E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02485 ca5f62e665c93f94f12c49a0e7d9fa5a 310 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 9.2E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02485 ca5f62e665c93f94f12c49a0e7d9fa5a 310 Pfam PF13411 MerR HTH family regulatory protein 7 74 6.8E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02485 ca5f62e665c93f94f12c49a0e7d9fa5a 310 Gene3D G3DSA:1.10.1660.10 3 62 1.0E-22 T 28-03-2018 SMD44_RS02485 ca5f62e665c93f94f12c49a0e7d9fa5a 310 SUPERFAMILY SSF46955 7 109 6.96E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS07205 51045a9bf764ee87aa7e8873ffc1a3e5 310 SUPERFAMILY SSF53328 2 206 1.15E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS07205 51045a9bf764ee87aa7e8873ffc1a3e5 310 Gene3D G3DSA:3.10.25.10 207 310 1.3E-30 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS07205 51045a9bf764ee87aa7e8873ffc1a3e5 310 Gene3D G3DSA:3.40.50.170 1 206 1.1E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS07205 51045a9bf764ee87aa7e8873ffc1a3e5 310 SUPERFAMILY SSF50486 205 308 1.73E-30 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMD44_RS07205 51045a9bf764ee87aa7e8873ffc1a3e5 310 Pfam PF00551 Formyl transferase 3 177 2.6E-33 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS07205 51045a9bf764ee87aa7e8873ffc1a3e5 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 301 1.1E-68 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SMD44_RS07205 51045a9bf764ee87aa7e8873ffc1a3e5 310 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 8.7E-26 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS07205 51045a9bf764ee87aa7e8873ffc1a3e5 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 32.994 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SMD44_RS24360 805cb47a96ae6167da94af94a88d4cdb 214 SUPERFAMILY SSF52833 75 213 7.28E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS24360 805cb47a96ae6167da94af94a88d4cdb 214 Pfam PF00578 AhpC/TSA family 73 192 6.3E-22 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD44_RS24360 805cb47a96ae6167da94af94a88d4cdb 214 Gene3D G3DSA:3.40.30.10 2 214 1.0E-30 T 28-03-2018 SMD44_RS24360 805cb47a96ae6167da94af94a88d4cdb 214 ProSitePatterns PS00194 Thioredoxin family active site. 99 117 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMD44_RS34835 606d0328ffdb2b9577d5661053599bb9 423 Gene3D G3DSA:1.10.443.10 193 411 1.7E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS34835 606d0328ffdb2b9577d5661053599bb9 423 Gene3D G3DSA:1.10.150.130 70 190 4.1E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS34835 606d0328ffdb2b9577d5661053599bb9 423 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 79 128 2.9E-6 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMD44_RS34835 606d0328ffdb2b9577d5661053599bb9 423 SUPERFAMILY SSF56349 77 408 6.08E-37 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS34835 606d0328ffdb2b9577d5661053599bb9 423 Pfam PF00589 Phage integrase family 224 403 1.9E-9 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS10320 03873b87f535cd97fc54bdbb5fa52fe4 273 Pfam PF04672 S-adenosyl methyltransferase 12 272 2.5E-111 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS10320 03873b87f535cd97fc54bdbb5fa52fe4 273 PIRSF PIRSF017393 1 273 1.7E-97 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS10320 03873b87f535cd97fc54bdbb5fa52fe4 273 SUPERFAMILY SSF53335 20 254 1.92E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS10320 03873b87f535cd97fc54bdbb5fa52fe4 273 Gene3D G3DSA:3.40.50.150 2 273 1.8E-52 T 28-03-2018 SMD44_RS26915 7b236aad9738b332e4f453ac7e5ae2f8 406 SUPERFAMILY SSF50939 231 395 5.69E-11 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD44_RS26915 7b236aad9738b332e4f453ac7e5ae2f8 406 SUPERFAMILY SSF50939 107 171 5.69E-11 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD44_RS26915 7b236aad9738b332e4f453ac7e5ae2f8 406 Gene3D G3DSA:2.120.10.10 315 402 0.031 T 28-03-2018 SMD44_RS26915 7b236aad9738b332e4f453ac7e5ae2f8 406 Gene3D G3DSA:2.120.10.10 76 314 7.1E-14 T 28-03-2018 SMD44_RS12925 686801feb89d3207ef300348803b305d 813 Gene3D G3DSA:3.40.50.2300 37 163 1.9E-5 T 28-03-2018 SMD44_RS12925 686801feb89d3207ef300348803b305d 813 SUPERFAMILY SSF52172 32 167 6.22E-7 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS12925 686801feb89d3207ef300348803b305d 813 SUPERFAMILY SSF55073 175 324 7.38E-5 T 28-03-2018 IPR029787 Nucleotide cyclase SMD44_RS12925 686801feb89d3207ef300348803b305d 813 Pfam PF13641 Glycosyltransferase like family 2 442 664 6.4E-28 T 28-03-2018 SMD44_RS12925 686801feb89d3207ef300348803b305d 813 Gene3D G3DSA:3.30.70.270 166 347 4.0E-14 T 28-03-2018 SMD44_RS12925 686801feb89d3207ef300348803b305d 813 SUPERFAMILY SSF53448 443 689 1.22E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS12925 686801feb89d3207ef300348803b305d 813 Gene3D G3DSA:3.90.550.10 425 693 3.9E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 5.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 5.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 5.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 5.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 5.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 SUPERFAMILY SSF51735 11 257 4.27E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 Gene3D G3DSA:3.40.50.720 4 49 1.6E-12 T 28-03-2018 SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 Gene3D G3DSA:3.40.50.720 50 258 2.5E-55 T 28-03-2018 SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 256 2.9E-62 T 28-03-2018 SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 194 9.2E-4 T 28-03-2018 SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 6.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 6.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13430 6d7e0c685b6f64e03c0280da40595eb5 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 6.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 425 447 1.9E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 261 283 1.9E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 83 103 1.9E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 1.4E-48 T 28-03-2018 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 426 445 1.4E-48 T 28-03-2018 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 1.4E-48 T 28-03-2018 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 1.4E-48 T 28-03-2018 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 1.4E-48 T 28-03-2018 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 1.4E-48 T 28-03-2018 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 1.4E-48 T 28-03-2018 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 Pfam PF00361 Proton-conducting membrane transporter 132 403 1.3E-73 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 655 8.2E-138 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25295 9859bd7f5a9d7eeb357d8a68e815a831 664 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 68 119 3.8E-10 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 SMART SM00382 158 344 3.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 Gene3D G3DSA:1.10.1140.10 365 475 3.3E-34 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 88 2.2E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 Gene3D G3DSA:3.40.50.300 91 364 1.7E-87 T 28-03-2018 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 359 9.3E-64 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 Gene3D G3DSA:2.40.10.170 2 90 3.1E-30 T 28-03-2018 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 SUPERFAMILY SSF50615 11 89 1.28E-26 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 SUPERFAMILY SSF47917 362 477 7.85E-45 T 28-03-2018 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 SUPERFAMILY SSF52540 92 364 1.84E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 Hamap MF_01347 ATP synthase subunit beta [atpB]. 9 477 54.293 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 SMD44_RS28895 71a3887a07aa5e775db7c3974c9b1f4a 480 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 11 477 9.3E-237 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 SMD44_RS40090 f76ce24934a0e7f53c02bec22c1a327e 612 Gene3D G3DSA:3.10.105.10 340 572 4.0E-33 T 28-03-2018 SMD44_RS40090 f76ce24934a0e7f53c02bec22c1a327e 612 SUPERFAMILY SSF53850 100 209 2.53E-74 T 28-03-2018 SMD44_RS40090 f76ce24934a0e7f53c02bec22c1a327e 612 SUPERFAMILY SSF53850 237 604 2.53E-74 T 28-03-2018 SMD44_RS40090 f76ce24934a0e7f53c02bec22c1a327e 612 Gene3D G3DSA:3.40.190.10 236 339 3.4E-13 T 28-03-2018 SMD44_RS40090 f76ce24934a0e7f53c02bec22c1a327e 612 PIRSF PIRSF002741 93 212 7.8E-15 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS40090 f76ce24934a0e7f53c02bec22c1a327e 612 PIRSF PIRSF002741 227 608 2.0E-33 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS40090 f76ce24934a0e7f53c02bec22c1a327e 612 Gene3D G3DSA:3.90.76.10 64 212 5.6E-23 T 28-03-2018 SMD44_RS40090 f76ce24934a0e7f53c02bec22c1a327e 612 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 526 1.6E-57 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 Gene3D G3DSA:2.40.10.10 29 61 7.2E-9 T 28-03-2018 SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 SUPERFAMILY SSF50494 6 243 1.73E-28 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 Gene3D G3DSA:2.40.10.10 62 244 4.9E-22 T 28-03-2018 SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 SMART SM00020 28 238 1.9E-8 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 63 68 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 191 203 5.5E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 106 120 5.5E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 53 68 5.5E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS41845 79e809023935e3f1e6f2c631dcf7e820 244 Pfam PF00089 Trypsin 34 232 2.6E-21 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 PRINTS PR00783 Major intrinsic protein family signature 47 71 8.8E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 PRINTS PR00783 Major intrinsic protein family signature 241 261 8.8E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 PRINTS PR00783 Major intrinsic protein family signature 161 179 8.8E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 PRINTS PR00783 Major intrinsic protein family signature 194 216 8.8E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 PRINTS PR00783 Major intrinsic protein family signature 84 103 8.8E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 PRINTS PR00783 Major intrinsic protein family signature 5 24 8.8E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 TIGRFAM TIGR00861 MIP: MIP family channel proteins 10 258 5.7E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 Pfam PF00230 Major intrinsic protein 6 258 4.6E-44 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 SUPERFAMILY SSF81338 7 261 3.92E-64 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 ProSitePatterns PS00221 MIP family signature. 65 73 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD44_RS08235 2c089f3072eec0d4baded8df2c17925e 261 Gene3D G3DSA:1.20.1080.10 2 261 3.8E-80 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 Gene3D G3DSA:3.40.50.670 464 700 1.4E-94 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 Gene3D G3DSA:3.30.565.10 58 285 6.3E-73 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 Pfam PF01751 Toprim domain 483 594 2.6E-17 T 28-03-2018 IPR006171 TOPRIM domain SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 SUPERFAMILY SSF55874 48 253 1.51E-69 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 281 303 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 656 668 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 237 250 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 376 392 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 424 438 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 48 58 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 438 458 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 222 237 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 306 324 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 672 688 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR01159 DNA gyrase subunit B signature 534 543 1.4E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 75 214 9.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 634 692 2.9E-23 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 484 498 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 155 169 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 635 651 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 77 92 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 112 125 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 568 585 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 332 345 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 550 566 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 PRINTS PR00418 DNA topoisomerase II family signature 588 600 8.0E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 SMART SM00433 77 696 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 Pfam PF00204 DNA gyrase B 282 454 8.1E-62 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 48 703 7.4E-285 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 45 703 88.163 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 Gene3D G3DSA:3.30.230.10 286 456 2.9E-60 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 SUPERFAMILY SSF54211 282 455 2.09E-54 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 SUPERFAMILY SSF56719 458 698 4.18E-82 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 ProSitePatterns PS00177 DNA topoisomerase II signature. 486 494 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS21150 6b662a1c77134c2af912e52981225db4 703 SMART SM00387 73 217 6.9E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11850 6b1d2d267248b6beeb9ed999afeea5ea 289 Pfam PF14378 PAP2 superfamily 79 259 6.5E-47 T 28-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 Pfam PF01628 HrcA protein C terminal domain 103 321 6.2E-63 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 Pfam PF08220 DeoR-like helix-turn-helix domain 34 62 6.3E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 Gene3D G3DSA:3.30.450.40 185 338 3.1E-40 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 SUPERFAMILY SSF46785 1 82 2.21E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 Gene3D G3DSA:1.10.10.10 1 85 2.8E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.613 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 PIRSF PIRSF005485 1 338 1.2E-101 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 1.9E-103 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMD44_RS13800 0c5954e5a98738c03eb9b793fa427215 338 SUPERFAMILY SSF55781 71 336 5.89E-59 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS12090 6c1ad9be2175e381effbc81cbc2757c1 647 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 283 602 2.6E-83 T 28-03-2018 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 SMD44_RS12090 6c1ad9be2175e381effbc81cbc2757c1 647 Gene3D G3DSA:3.20.20.70 268 455 0.0019 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS07990 3447dc3815f146371cb0a45bfc667adc 484 PIRSF PIRSF006060 16 483 1.0E-67 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS07990 3447dc3815f146371cb0a45bfc667adc 484 TIGRFAM TIGR00908 2A0305: ethanolamine permease 23 470 4.5E-148 T 28-03-2018 IPR004757 Ethanolamine permease SMD44_RS07990 3447dc3815f146371cb0a45bfc667adc 484 Pfam PF13520 Amino acid permease 42 447 1.8E-41 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS28755 c2cb0964b2d2e4a6a30e56d8112b68ac 373 SUPERFAMILY SSF100939 1 255 8.04E-46 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain SMD44_RS28755 c2cb0964b2d2e4a6a30e56d8112b68ac 373 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 256 5.4E-88 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMD44_RS28755 c2cb0964b2d2e4a6a30e56d8112b68ac 373 PIRSF PIRSF006493 1 302 7.9E-76 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMD44_RS28755 c2cb0964b2d2e4a6a30e56d8112b68ac 373 PIRSF PIRSF006493 290 372 3700.0 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMD44_RS28755 c2cb0964b2d2e4a6a30e56d8112b68ac 373 SMART SM00559 52 181 1.2E-43 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 SMD44_RS28755 c2cb0964b2d2e4a6a30e56d8112b68ac 373 Gene3D G3DSA:2.40.290.10 1 181 2.9E-30 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain SMD44_RS28755 c2cb0964b2d2e4a6a30e56d8112b68ac 373 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 190 1.4E-32 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 SMD44_RS28755 c2cb0964b2d2e4a6a30e56d8112b68ac 373 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 254 30.289 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMD44_RS39905 13f6fc6eedc23a670db13cc645b898cb 383 Pfam PF00296 Luciferase-like monooxygenase 14 329 9.3E-67 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS39905 13f6fc6eedc23a670db13cc645b898cb 383 SUPERFAMILY SSF51679 13 360 5.76E-73 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS39905 13f6fc6eedc23a670db13cc645b898cb 383 Gene3D G3DSA:3.20.20.30 3 362 4.2E-72 T 28-03-2018 SMD44_RS20415 434d56cd0b41960b7f5e075af5c087dd 195 Gene3D G3DSA:1.10.357.10 3 194 9.6E-36 T 28-03-2018 SMD44_RS20415 434d56cd0b41960b7f5e075af5c087dd 195 SUPERFAMILY SSF48498 76 191 3.46E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS20415 434d56cd0b41960b7f5e075af5c087dd 195 SUPERFAMILY SSF46689 4 83 3.49E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS20415 434d56cd0b41960b7f5e075af5c087dd 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS14035 0a66b592d9b3c57edb122f2c55743db5 645 Pfam PF04055 Radical SAM superfamily 268 433 4.1E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS14035 0a66b592d9b3c57edb122f2c55743db5 645 SMART SM00729 264 487 6.3E-30 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS14035 0a66b592d9b3c57edb122f2c55743db5 645 Gene3D G3DSA:3.20.20.70 145 576 4.1E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS14035 0a66b592d9b3c57edb122f2c55743db5 645 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 12 618 4.7E-212 T 28-03-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM SMD44_RS14035 0a66b592d9b3c57edb122f2c55743db5 645 SUPERFAMILY SSF102114 232 634 9.94E-52 T 28-03-2018 SMD44_RS06360 43aa1d5ca3a72b5a1479d11519d5fd63 199 SUPERFAMILY SSF50475 4 114 9.64E-8 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS06360 43aa1d5ca3a72b5a1479d11519d5fd63 199 Gene3D G3DSA:2.30.110.10 3 187 4.5E-8 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS32960 c5045c0cca71126ffaeeab9532a0358d 343 Gene3D G3DSA:1.10.10.10 168 323 8.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32960 c5045c0cca71126ffaeeab9532a0358d 343 SMART SM00421 261 318 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32960 c5045c0cca71126ffaeeab9532a0358d 343 SUPERFAMILY SSF46894 268 324 8.16E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS32960 c5045c0cca71126ffaeeab9532a0358d 343 SUPERFAMILY SSF46785 2 84 2.18E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32960 c5045c0cca71126ffaeeab9532a0358d 343 Gene3D G3DSA:1.10.10.10 1 113 2.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32960 c5045c0cca71126ffaeeab9532a0358d 343 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 68 3.9E-6 T 28-03-2018 IPR002831 Transcription regulator TrmB, N-terminal SMD44_RS36065 011f3feda9e922ddbb18bd075fdfe308 311 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 18 293 5.8E-78 T 28-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 SMD44_RS36065 011f3feda9e922ddbb18bd075fdfe308 311 Gene3D G3DSA:3.20.10.10 147 292 2.9E-42 T 28-03-2018 SMD44_RS36065 011f3feda9e922ddbb18bd075fdfe308 311 ProSitePatterns PS00770 Aminotransferases class-IV signature. 195 223 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS36065 011f3feda9e922ddbb18bd075fdfe308 311 SUPERFAMILY SSF56752 11 294 6.54E-89 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS36065 011f3feda9e922ddbb18bd075fdfe308 311 Gene3D G3DSA:3.30.470.10 9 146 1.7E-38 T 28-03-2018 SMD44_RS36065 011f3feda9e922ddbb18bd075fdfe308 311 Pfam PF01063 Amino-transferase class IV 44 268 1.2E-50 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS42860 2a9a251e84cc3c809ce80a9d6b5b45dc 430 Gene3D G3DSA:3.30.565.10 5 313 1.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42860 2a9a251e84cc3c809ce80a9d6b5b45dc 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 204 311 8.5E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42860 2a9a251e84cc3c809ce80a9d6b5b45dc 430 SUPERFAMILY SSF55874 191 311 1.83E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42860 2a9a251e84cc3c809ce80a9d6b5b45dc 430 SMART SM00387 200 314 2.2E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09335 62dd04a4856f543d3c34f25f593811e5 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 93 5.6E-9 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS09335 62dd04a4856f543d3c34f25f593811e5 172 SUPERFAMILY SSF53254 7 154 3.0E-22 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS09335 62dd04a4856f543d3c34f25f593811e5 172 Gene3D G3DSA:3.40.50.1240 2 172 1.2E-31 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS36685 7755f9d838f9b89ae50bf043b69e9684 396 Gene3D G3DSA:3.90.180.10 3 163 2.2E-32 T 28-03-2018 SMD44_RS36685 7755f9d838f9b89ae50bf043b69e9684 396 SUPERFAMILY SSF51735 142 331 6.44E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36685 7755f9d838f9b89ae50bf043b69e9684 396 SMART SM00829 37 364 3.9E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS36685 7755f9d838f9b89ae50bf043b69e9684 396 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 57 114 8.3E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS36685 7755f9d838f9b89ae50bf043b69e9684 396 Pfam PF13602 Zinc-binding dehydrogenase 216 364 1.1E-19 T 28-03-2018 SMD44_RS36685 7755f9d838f9b89ae50bf043b69e9684 396 SUPERFAMILY SSF50129 36 168 6.24E-29 T 28-03-2018 IPR011032 GroES-like SMD44_RS36685 7755f9d838f9b89ae50bf043b69e9684 396 Gene3D G3DSA:3.40.50.720 164 350 1.6E-30 T 28-03-2018 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 Pfam PF00072 Response regulator receiver domain 4 118 8.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 SMART SM00421 153 210 3.3E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 4.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 4.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 4.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 Gene3D G3DSA:3.40.50.2300 1 135 5.0E-39 T 28-03-2018 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 SUPERFAMILY SSF46894 137 216 9.86E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 SMART SM00448 2 117 1.8E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 Gene3D G3DSA:1.10.10.10 136 215 1.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02640 a5c016905b8e179661f8c61b2ab404a9 221 SUPERFAMILY SSF52172 2 136 3.7E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS00085 92cb933b4243a60b8895367c772afc3e 324 SUPERFAMILY SSF47413 16 69 2.62E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS00085 92cb933b4243a60b8895367c772afc3e 324 Gene3D G3DSA:1.10.260.40 6 70 9.3E-13 T 28-03-2018 SMD44_RS00085 92cb933b4243a60b8895367c772afc3e 324 Pfam PF13560 Helix-turn-helix domain 16 71 3.3E-9 T 28-03-2018 SMD44_RS00085 92cb933b4243a60b8895367c772afc3e 324 SMART SM00530 20 75 6.4E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS09995 f3f67d7f55ff5bb6e2d38ea0f1d57352 420 Gene3D G3DSA:3.90.1150.10 295 415 3.0E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS09995 f3f67d7f55ff5bb6e2d38ea0f1d57352 420 SUPERFAMILY SSF53383 11 415 1.06E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS09995 f3f67d7f55ff5bb6e2d38ea0f1d57352 420 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 14 420 5.3E-185 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMD44_RS09995 f3f67d7f55ff5bb6e2d38ea0f1d57352 420 Pfam PF00266 Aminotransferase class-V 33 408 5.0E-151 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS09995 f3f67d7f55ff5bb6e2d38ea0f1d57352 420 Gene3D G3DSA:3.40.640.10 41 294 1.3E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS09995 f3f67d7f55ff5bb6e2d38ea0f1d57352 420 PIRSF PIRSF005572 30 417 4.6E-48 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 SUPERFAMILY SSF52540 227 451 6.79E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 52 565 4.7E-253 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 417 1.1E-47 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 SMART SM00382 265 419 4.5E-22 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 Pfam PF16450 Proteasomal ATPase OB/ID domain 97 226 3.0E-53 T 28-03-2018 IPR032501 Proteasomal ATPase, OB/ID domain SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 54 566 50.209 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 ProSitePatterns PS00674 AAA-protein family signature. 387 405 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 Gene3D G3DSA:3.40.50.300 211 452 5.4E-53 T 28-03-2018 SMD44_RS08165 09495b4a0338449f307ea7619b580436 588 Gene3D G3DSA:1.20.5.340 18 168 8.8E-7 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 SUPERFAMILY SSF52777 2 154 3.34E-27 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 442 845 2.6E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 ProSitePatterns PS00455 Putative AMP-binding domain signature. 567 578 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Gene3D G3DSA:2.30.38.10 722 813 6.8E-21 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Gene3D G3DSA:3.40.50.980 412 572 5.2E-46 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Pfam PF00668 Condensation domain 3 402 6.4E-66 T 28-03-2018 IPR001242 Condensation domain SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 SUPERFAMILY SSF53335 881 1056 2.94E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Gene3D G3DSA:3.40.50.150 873 1200 1.7E-31 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 SUPERFAMILY SSF56801 379 885 5.63E-130 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Pfam PF00501 AMP-binding enzyme 421 821 4.3E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 SUPERFAMILY SSF52777 140 408 8.45E-47 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Gene3D G3DSA:3.30.559.10 1 159 1.2E-29 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Pfam PF08242 Methyltransferase domain 937 1036 1.4E-13 T 28-03-2018 IPR013217 Methyltransferase type 12 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Gene3D G3DSA:3.40.50.980 573 721 2.9E-31 T 28-03-2018 SMD44_RS38895 10aa1f86395727e085a3f4ce0d9c0b51 1526 Pfam PF13193 AMP-binding enzyme C-terminal domain 829 870 5.5E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS32725 5c4fd5bfd52583b752e90421b652fdb9 288 Gene3D G3DSA:1.20.58.370 2 35 7.0E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMD44_RS32725 5c4fd5bfd52583b752e90421b652fdb9 288 Gene3D G3DSA:1.10.3720.10 55 284 1.0E-47 T 28-03-2018 SMD44_RS32725 5c4fd5bfd52583b752e90421b652fdb9 288 SUPERFAMILY SSF161098 50 275 1.31E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS32725 5c4fd5bfd52583b752e90421b652fdb9 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 276 6.1E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 SUPERFAMILY SSF46689 34 94 3.01E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 SUPERFAMILY SSF48498 106 240 3.22E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 Gene3D G3DSA:1.10.357.10 110 257 6.7E-21 T 28-03-2018 SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 240 7.2E-6 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 66 89 5.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 58 5.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 88 5.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 Gene3D G3DSA:1.10.10.60 29 66 1.6E-14 T 28-03-2018 SMD44_RS25750 6fb33b9f51b7980c878f851236eeafb9 257 Gene3D G3DSA:1.10.260.40 67 109 9.4E-11 T 28-03-2018 SMD44_RS17030 7e6d77859c0bfcba6ecfcf4e07ed2d90 157 SUPERFAMILY SSF69118 17 154 3.8E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS17030 7e6d77859c0bfcba6ecfcf4e07ed2d90 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 95 2.1E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS17030 7e6d77859c0bfcba6ecfcf4e07ed2d90 157 Gene3D G3DSA:1.20.1290.10 1 153 1.7E-33 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS17030 7e6d77859c0bfcba6ecfcf4e07ed2d90 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 32 80 1.9E-19 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 Gene3D G3DSA:3.30.420.180 188 324 2.9E-41 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 SUPERFAMILY SSF53790 323 563 4.97E-53 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 Pfam PF01890 Cobalamin synthesis G C-terminus 198 319 1.1E-32 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 SUPERFAMILY SSF159672 2 204 3.53E-47 T 28-03-2018 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 328 563 5.3E-84 T 28-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 Gene3D G3DSA:3.30.950.10 445 562 2.6E-58 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 SUPERFAMILY SSF159664 192 322 3.66E-33 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 327 532 7.5E-39 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 Pfam PF11760 Cobalamin synthesis G N-terminal 36 116 5.0E-32 T 28-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 SMD44_RS09655 92ae7c35bf63e8625849fe62e4e3b561 568 Gene3D G3DSA:3.40.1010.10 325 444 1.6E-28 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS42765 669351bffd6268f580fbdf7bca3855ad 242 Pfam PF04055 Radical SAM superfamily 45 149 7.9E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS42765 669351bffd6268f580fbdf7bca3855ad 242 Pfam PF13394 4Fe-4S single cluster domain 40 131 3.9E-14 T 28-03-2018 SMD44_RS42765 669351bffd6268f580fbdf7bca3855ad 242 PIRSF PIRSF000370 13 242 8.4E-45 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 SMD44_RS42765 669351bffd6268f580fbdf7bca3855ad 242 SUPERFAMILY SSF102114 41 132 3.53E-15 T 28-03-2018 SMD44_RS42765 669351bffd6268f580fbdf7bca3855ad 242 Gene3D G3DSA:3.20.20.70 44 220 1.9E-16 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS42765 669351bffd6268f580fbdf7bca3855ad 242 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 15 239 34.661 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 SMD44_RS07315 5bf20bb81842d4abcf876deb7695c56c 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 19 346 1.1E-104 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD44_RS07315 5bf20bb81842d4abcf876deb7695c56c 363 Pfam PF01761 3-dehydroquinate synthase 71 327 2.7E-91 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD44_RS07315 5bf20bb81842d4abcf876deb7695c56c 363 PIRSF PIRSF001455 13 360 2.0E-96 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD44_RS07315 5bf20bb81842d4abcf876deb7695c56c 363 Gene3D G3DSA:3.40.50.1970 10 176 1.1E-40 T 28-03-2018 SMD44_RS07315 5bf20bb81842d4abcf876deb7695c56c 363 SUPERFAMILY SSF56796 16 358 5.5E-98 T 28-03-2018 SMD44_RS07315 5bf20bb81842d4abcf876deb7695c56c 363 Gene3D G3DSA:1.20.1090.10 177 363 3.7E-56 T 28-03-2018 SMD44_RS07315 5bf20bb81842d4abcf876deb7695c56c 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 360 35.868 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 33 137 9.2E-30 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 SUPERFAMILY SSF54665 17 139 1.14E-38 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 157 701 4.5E-107 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 Gene3D G3DSA:3.30.365.10 589 760 1.3E-32 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 Gene3D G3DSA:3.30.365.10 269 418 7.8E-40 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 Gene3D G3DSA:3.90.1170.50 16 138 1.6E-34 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 SMART SM01008 32 138 4.3E-44 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 Gene3D G3DSA:3.30.365.10 462 588 3.9E-23 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 SUPERFAMILY SSF56003 139 755 7.72E-121 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS15885 26f332fb86edbdf97f1c9ea8fabc6a4e 763 Gene3D G3DSA:3.30.365.10 165 268 6.0E-19 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 Gene3D G3DSA:1.10.238.10 118 160 0.08 T 28-03-2018 SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 ProSitePatterns PS00018 EF-hand calcium-binding domain. 69 81 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 Gene3D G3DSA:1.10.238.10 1 29 5.7E-6 T 28-03-2018 SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 Gene3D G3DSA:1.10.238.10 77 117 1.0E-7 T 28-03-2018 SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 SUPERFAMILY SSF47473 3 135 1.76E-20 T 28-03-2018 IPR011992 EF-hand domain pair SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 ProSitePatterns PS00018 EF-hand calcium-binding domain. 18 30 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 Pfam PF13499 EF-hand domain pair 8 82 3.6E-8 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 ProSitePatterns PS00018 EF-hand calcium-binding domain. 112 124 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 Gene3D G3DSA:1.10.238.10 30 76 3.3E-9 T 28-03-2018 SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 SMART SM00054 60 88 4.9 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 SMART SM00054 9 37 0.0019 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SMD44_RS18105 923096f13784ef10faf90d514f0aae05 165 SMART SM00054 103 131 8.3 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 Gene3D G3DSA:3.40.1190.10 114 348 4.4E-55 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 Pfam PF01225 Mur ligase family, catalytic domain 35 110 3.4E-11 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 Pfam PF08245 Mur ligase middle domain 123 323 2.8E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 Gene3D G3DSA:3.40.1390.10 11 113 3.5E-27 T 28-03-2018 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 15 501 33.474 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 Gene3D G3DSA:3.90.190.20 349 506 1.1E-47 T 28-03-2018 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 SUPERFAMILY SSF53244 344 503 8.77E-45 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 SUPERFAMILY SSF53623 114 343 1.26E-64 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 SUPERFAMILY SSF63418 17 114 2.75E-22 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 Pfam PF02875 Mur ligase family, glutamate ligase domain 344 428 1.8E-20 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS11055 42bf9637c58160ef6e4ea50fe7464acd 506 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 33 501 2.8E-145 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMD44_RS17555 a999702389ca6e2f9ec4591c7236c0b7 208 SUPERFAMILY SSF55781 6 134 1.72E-14 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS17555 a999702389ca6e2f9ec4591c7236c0b7 208 Pfam PF13185 GAF domain 23 133 4.7E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS17555 a999702389ca6e2f9ec4591c7236c0b7 208 SMART SM01012 126 197 1.1E-6 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS17555 a999702389ca6e2f9ec4591c7236c0b7 208 Gene3D G3DSA:1.10.10.10 151 199 2.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17555 a999702389ca6e2f9ec4591c7236c0b7 208 Gene3D G3DSA:3.30.450.40 3 137 1.8E-16 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS17555 a999702389ca6e2f9ec4591c7236c0b7 208 Pfam PF03861 ANTAR domain 152 197 1.0E-6 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS20735 9f7bce7a71105321dcc06f5e1a42fe5b 276 SUPERFAMILY SSF56784 15 275 1.23E-56 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS20735 9f7bce7a71105321dcc06f5e1a42fe5b 276 Pfam PF08282 haloacid dehalogenase-like hydrolase 157 271 5.5E-28 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS20735 9f7bce7a71105321dcc06f5e1a42fe5b 276 Pfam PF08282 haloacid dehalogenase-like hydrolase 18 101 8.1E-15 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS20735 9f7bce7a71105321dcc06f5e1a42fe5b 276 Gene3D G3DSA:3.40.50.1000 12 276 1.4E-38 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS20735 9f7bce7a71105321dcc06f5e1a42fe5b 276 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 17 94 9.4E-12 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SMD44_RS20735 9f7bce7a71105321dcc06f5e1a42fe5b 276 ProSitePatterns PS01228 Hypothetical cof family signature 1. 17 28 - T 28-03-2018 SMD44_RS12950 0c40c926600342e2d9ed4db6d190f2ed 261 Gene3D G3DSA:1.25.40.10 3 164 3.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12950 0c40c926600342e2d9ed4db6d190f2ed 261 Gene3D G3DSA:1.25.40.10 165 244 0.0023 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12950 0c40c926600342e2d9ed4db6d190f2ed 261 SUPERFAMILY SSF48452 24 223 3.8E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS16620 857631bbc42a14d2ad575938509c3e7d 451 SUPERFAMILY SSF51338 335 449 1.1E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS16620 857631bbc42a14d2ad575938509c3e7d 451 Pfam PF01979 Amidohydrolase family 52 426 5.8E-42 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS16620 857631bbc42a14d2ad575938509c3e7d 451 Gene3D G3DSA:2.30.40.10 2 59 3.7E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS16620 857631bbc42a14d2ad575938509c3e7d 451 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 3 450 4.1E-163 T 28-03-2018 IPR010252 Formiminoglutamate deiminase SMD44_RS16620 857631bbc42a14d2ad575938509c3e7d 451 Gene3D G3DSA:3.20.20.140 60 393 1.2E-48 T 28-03-2018 SMD44_RS16620 857631bbc42a14d2ad575938509c3e7d 451 SUPERFAMILY SSF51556 53 374 2.61E-69 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS14060 7d492b3e905c3afee2874ed58432df1e 317 PIRSF PIRSF038471 2 282 5.1E-41 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 SMD44_RS14060 7d492b3e905c3afee2874ed58432df1e 317 Pfam PF04085 rod shape-determining protein MreC 131 270 2.7E-33 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 SMD44_RS43715 760ddd402b6a5e0a2ed8ea13a37f309e 157 Gene3D G3DSA:2.40.30.70 5 149 4.8E-27 T 28-03-2018 IPR023370 TsaA-like domain SMD44_RS43715 760ddd402b6a5e0a2ed8ea13a37f309e 157 Pfam PF01980 Uncharacterised protein family UPF0066 27 132 3.7E-21 T 28-03-2018 IPR023370 TsaA-like domain SMD44_RS43715 760ddd402b6a5e0a2ed8ea13a37f309e 157 SUPERFAMILY SSF118196 2 153 1.11E-34 T 28-03-2018 IPR023370 TsaA-like domain SMD44_RS41575 2a8dd2b2e05f2ee791c8b2f12b13c071 79 Pfam PF03595 Voltage-dependent anion channel 19 76 4.3E-9 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 7.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 SMART SM00448 4 117 1.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 8.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 8.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 8.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 Gene3D G3DSA:3.40.50.2300 3 128 4.7E-38 T 28-03-2018 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 SMART SM00421 156 213 8.2E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 Pfam PF00072 Response regulator receiver domain 7 118 1.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 SUPERFAMILY SSF52172 3 136 2.85E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 Gene3D G3DSA:1.10.10.10 129 222 3.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33585 2fe67856562c86a88e0f081a4bb2a9b1 222 SUPERFAMILY SSF46894 148 220 2.89E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS29590 0283262fdbfe13dbfe95a3509db5be1f 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 71 4.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS29590 0283262fdbfe13dbfe95a3509db5be1f 283 SUPERFAMILY SSF53850 70 269 2.09E-19 T 28-03-2018 SMD44_RS29590 0283262fdbfe13dbfe95a3509db5be1f 283 Pfam PF03466 LysR substrate binding domain 69 263 7.3E-20 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS29590 0283262fdbfe13dbfe95a3509db5be1f 283 Gene3D G3DSA:3.40.190.10 62 150 3.1E-14 T 28-03-2018 SMD44_RS29590 0283262fdbfe13dbfe95a3509db5be1f 283 Gene3D G3DSA:3.40.190.10 151 238 2.5E-8 T 28-03-2018 SMD44_RS29590 0283262fdbfe13dbfe95a3509db5be1f 283 SUPERFAMILY SSF46785 18 84 2.81E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22980 da4ed451074ea0b04617e19e22eec5bf 484 Pfam PF01937 Protein of unknown function DUF89 212 342 9.5E-11 T 28-03-2018 IPR002791 Domain of unknown function DUF89 SMD44_RS22980 da4ed451074ea0b04617e19e22eec5bf 484 SUPERFAMILY SSF111321 143 353 2.75E-17 T 28-03-2018 IPR002791 Domain of unknown function DUF89 SMD44_RS26050 12ff2117d721d3f5976d668c8353d8ff 654 SUPERFAMILY SSF56112 198 493 3.46E-42 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS26050 12ff2117d721d3f5976d668c8353d8ff 654 Pfam PF00069 Protein kinase domain 252 483 2.9E-28 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS26050 12ff2117d721d3f5976d668c8353d8ff 654 Pfam PF03995 Peptidase inhibitor family I36 544 614 1.4E-9 T 28-03-2018 SMD44_RS26050 12ff2117d721d3f5976d668c8353d8ff 654 Gene3D G3DSA:3.30.200.20 194 346 1.3E-20 T 28-03-2018 SMD44_RS26050 12ff2117d721d3f5976d668c8353d8ff 654 SMART SM00220 205 492 1.0E-25 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS26050 12ff2117d721d3f5976d668c8353d8ff 654 Gene3D G3DSA:1.10.510.10 347 602 2.1E-30 T 28-03-2018 SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 72 3.8E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 Pfam PF07702 UTRA domain 97 232 1.4E-39 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 SUPERFAMILY SSF64288 60 238 3.3E-44 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 Gene3D G3DSA:3.40.1410.10 72 239 2.0E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 8.4E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 8.4E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 SUPERFAMILY SSF46785 11 81 3.87E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 SMART SM00345 15 72 2.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 SMART SM00866 92 232 3.0E-37 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS40300 bc7b6fb5790e1e854cb1af96d0dabddc 282 Gene3D G3DSA:1.10.10.10 1 71 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17955 034214a1203ab4a33188a549e978244b 377 SUPERFAMILY SSF53901 9 215 3.34E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS17955 034214a1203ab4a33188a549e978244b 377 Gene3D G3DSA:3.40.47.10 132 368 1.2E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS17955 034214a1203ab4a33188a549e978244b 377 Pfam PF02803 Thiolase, C-terminal domain 238 342 2.2E-6 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD44_RS17955 034214a1203ab4a33188a549e978244b 377 PIRSF PIRSF000429 3 352 4.4E-27 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS17955 034214a1203ab4a33188a549e978244b 377 SUPERFAMILY SSF53901 232 349 2.57E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS17955 034214a1203ab4a33188a549e978244b 377 Gene3D G3DSA:3.40.47.10 5 119 0.014 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 Gene3D G3DSA:3.30.200.20 2 108 5.1E-20 T 28-03-2018 SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 Pfam PF00069 Protein kinase domain 20 284 2.0E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 SMART SM00740 472 538 4.2E-9 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 SMART SM00220 20 287 2.6E-65 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 Pfam PF03793 PASTA domain 476 529 2.5E-10 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 SUPERFAMILY SSF56112 16 374 3.42E-74 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS21795 5b13d41dd8951ab8daee892f85479fce 544 Gene3D G3DSA:1.10.510.10 109 308 4.4E-50 T 28-03-2018 SMD44_RS22120 3b2c097cdbedc5a0f4f6c31685b70dab 158 SUPERFAMILY SSF51182 2 156 9.4E-39 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS22120 3b2c097cdbedc5a0f4f6c31685b70dab 158 Pfam PF06172 Cupin superfamily (DUF985) 4 134 1.6E-30 T 28-03-2018 IPR009327 Cupin domain of unknown function DUF985 SMD44_RS22120 3b2c097cdbedc5a0f4f6c31685b70dab 158 Gene3D G3DSA:2.60.120.10 1 157 7.8E-45 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS04970 ccd83dd9d74a14607958b56e1a9f3665 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS04970 ccd83dd9d74a14607958b56e1a9f3665 207 Gene3D G3DSA:1.10.260.40 42 107 1.4E-13 T 28-03-2018 SMD44_RS04970 ccd83dd9d74a14607958b56e1a9f3665 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.7E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04970 ccd83dd9d74a14607958b56e1a9f3665 207 Gene3D G3DSA:1.10.10.60 1 41 8.5E-16 T 28-03-2018 SMD44_RS04970 ccd83dd9d74a14607958b56e1a9f3665 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04970 ccd83dd9d74a14607958b56e1a9f3665 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04970 ccd83dd9d74a14607958b56e1a9f3665 207 SUPERFAMILY SSF46689 11 87 4.46E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 Gene3D G3DSA:3.90.180.10 1 189 5.6E-57 T 28-03-2018 SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 148 1.1E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 SMART SM00829 10 354 4.8E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 SUPERFAMILY SSF50129 1 195 3.65E-50 T 28-03-2018 IPR011032 GroES-like SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 Gene3D G3DSA:3.40.50.720 190 306 2.9E-20 T 28-03-2018 SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 Pfam PF00107 Zinc-binding dehydrogenase 191 314 3.0E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 SUPERFAMILY SSF50129 316 358 2.24E-5 T 28-03-2018 IPR011032 GroES-like SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS12265 9366bcb5d864c823792375fceb5163ed 360 SUPERFAMILY SSF51735 152 327 1.4E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS15455 1a5a74fb31a0d978f6cc15eb28ea1a87 176 SUPERFAMILY SSF46785 6 145 3.14E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15455 1a5a74fb31a0d978f6cc15eb28ea1a87 176 Gene3D G3DSA:1.10.10.10 4 161 1.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15455 1a5a74fb31a0d978f6cc15eb28ea1a87 176 Pfam PF01638 HxlR-like helix-turn-helix 20 104 3.1E-20 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 56 98 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 Gene3D G3DSA:1.10.10.60 61 108 4.4E-17 T 28-03-2018 SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 71 86 1.8E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 86 102 1.8E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 Pfam PF12833 Helix-turn-helix domain 25 103 8.7E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 Gene3D G3DSA:1.10.10.60 2 60 2.8E-17 T 28-03-2018 SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 SUPERFAMILY SSF46689 2 52 1.55E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 SUPERFAMILY SSF46689 55 106 3.18E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS23915 885d915c9009d334573b3ea6cbc97c1c 144 SMART SM00342 19 102 2.6E-34 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS06595 bccd581b280e714ac0282a7162213b73 120 Pfam PF05239 PRC-barrel domain 8 69 3.4E-10 T 28-03-2018 IPR027275 PRC-barrel domain SMD44_RS06595 bccd581b280e714ac0282a7162213b73 120 Gene3D G3DSA:3.90.50.10 2 110 1.0E-21 T 28-03-2018 SMD44_RS06595 bccd581b280e714ac0282a7162213b73 120 SUPERFAMILY SSF50346 6 109 1.73E-25 T 28-03-2018 IPR011033 PRC-barrel-like SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 656 32.88 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 SUPERFAMILY SSF52954 551 656 3.02E-28 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 343 551 1.0E-33 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 529 542 9.9E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 486 514 9.9E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 556 568 9.9E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 348 376 9.9E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 PRINTS PR01047 Threonyl-tRNA synthetase signature 381 404 9.9E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Pfam PF03129 Anticodon binding domain 563 651 1.8E-18 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 SMART SM00863 180 236 2.6E-19 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 SUPERFAMILY SSF55681 260 548 5.17E-88 T 28-03-2018 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Gene3D G3DSA:3.40.50.800 556 659 1.9E-25 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Gene3D G3DSA:3.30.54.20 145 191 2.1E-16 T 28-03-2018 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 652 5.5E-196 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Gene3D G3DSA:3.30.980.10 192 239 3.0E-14 T 28-03-2018 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 190 236 5.1E-13 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 SUPERFAMILY SSF55186 64 258 2.49E-50 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Gene3D G3DSA:3.30.980.10 68 144 4.0E-19 T 28-03-2018 SMD44_RS07520 a38f82f4c4f79e2a9ffdc819f68d4d5c 660 Gene3D G3DSA:3.30.930.10 240 553 1.3E-102 T 28-03-2018 SMD44_RS35195 b6c913f6cb2c38986010de9fd2a6cd57 251 Gene3D G3DSA:3.40.1080.10 1 251 2.7E-97 T 28-03-2018 SMD44_RS35195 b6c913f6cb2c38986010de9fd2a6cd57 251 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMD44_RS35195 b6c913f6cb2c38986010de9fd2a6cd57 251 SUPERFAMILY SSF100950 2 237 5.65E-82 T 28-03-2018 SMD44_RS35195 b6c913f6cb2c38986010de9fd2a6cd57 251 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 142 2.0E-41 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 SMD44_RS35195 b6c913f6cb2c38986010de9fd2a6cd57 251 Pfam PF01144 Coenzyme A transferase 6 233 1.7E-69 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMD44_RS35195 b6c913f6cb2c38986010de9fd2a6cd57 251 SMART SM00882 5 234 5.8E-78 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMD44_RS21620 7398c5ef1f1694daaa52f091beb53c65 440 PIRSF PIRSF000521 188 437 1.5E-16 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS21620 7398c5ef1f1694daaa52f091beb53c65 440 PIRSF PIRSF000521 49 177 0.0015 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS21620 7398c5ef1f1694daaa52f091beb53c65 440 Gene3D G3DSA:3.40.640.10 70 321 2.7E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS21620 7398c5ef1f1694daaa52f091beb53c65 440 Gene3D G3DSA:3.90.1150.10 322 440 1.5E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS21620 7398c5ef1f1694daaa52f091beb53c65 440 SUPERFAMILY SSF53383 42 434 1.15E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS21620 7398c5ef1f1694daaa52f091beb53c65 440 Pfam PF00202 Aminotransferase class-III 43 430 7.6E-68 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS21620 7398c5ef1f1694daaa52f091beb53c65 440 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS09165 909157104f47feab4f75f8a0afc1b162 301 Gene3D G3DSA:2.60.200.30 146 268 4.2E-38 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMD44_RS09165 909157104f47feab4f75f8a0afc1b162 301 SUPERFAMILY SSF111331 8 297 4.71E-78 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD44_RS09165 909157104f47feab4f75f8a0afc1b162 301 Hamap MF_00361 NAD kinase [nadK]. 7 291 29.301 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMD44_RS09165 909157104f47feab4f75f8a0afc1b162 301 Pfam PF01513 ATP-NAD kinase 57 275 2.0E-57 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMD44_RS09165 909157104f47feab4f75f8a0afc1b162 301 Gene3D G3DSA:3.40.50.10330 2 145 7.8E-34 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMD44_RS20175 98fae03d5a4a9012aa86ea1b4b17d6eb 194 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 191 1.9E-12 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD44_RS20175 98fae03d5a4a9012aa86ea1b4b17d6eb 194 Gene3D G3DSA:1.10.340.30 3 189 1.4E-11 T 28-03-2018 SMD44_RS20175 98fae03d5a4a9012aa86ea1b4b17d6eb 194 SUPERFAMILY SSF48150 19 167 9.74E-12 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD44_RS20175 98fae03d5a4a9012aa86ea1b4b17d6eb 194 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 193 3.0E-98 T 28-03-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD SMD44_RS26095 f4bdee378fd810795981ea8e87f69d66 164 SUPERFAMILY SSF47090 75 114 1.96E-5 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS26095 f4bdee378fd810795981ea8e87f69d66 164 Pfam PF01471 Putative peptidoglycan binding domain 77 114 4.8E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS26095 f4bdee378fd810795981ea8e87f69d66 164 Gene3D G3DSA:1.10.101.10 31 124 5.3E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS02330 e35a7a02c4b504dbc5e7a76bc0029906 627 Pfam PF03068 Protein-arginine deiminase (PAD) 211 622 7.4E-77 T 28-03-2018 IPR013530 Protein-arginine deiminase, C-terminal GO:0004668|GO:0005509|GO:0005737 MetaCyc: PWY-4921|Reactome: R-HSA-3247509 SMD44_RS02330 e35a7a02c4b504dbc5e7a76bc0029906 627 SUPERFAMILY SSF55909 288 621 3.14E-52 T 28-03-2018 SMD44_RS02330 e35a7a02c4b504dbc5e7a76bc0029906 627 Gene3D G3DSA:2.60.40.1700 44 224 1.5E-27 T 28-03-2018 IPR013733 Protein-arginine deiminase (PAD), central domain GO:0004668|GO:0005509|GO:0005737|GO:0018101 MetaCyc: PWY-4921|Reactome: R-HSA-3247509 SMD44_RS02330 e35a7a02c4b504dbc5e7a76bc0029906 627 SUPERFAMILY SSF110083 41 214 4.71E-11 T 28-03-2018 IPR013733 Protein-arginine deiminase (PAD), central domain GO:0004668|GO:0005509|GO:0005737|GO:0018101 MetaCyc: PWY-4921|Reactome: R-HSA-3247509 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Pfam PF01839 FG-GAP repeat 313 335 5.6E-8 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Pfam PF01839 FG-GAP repeat 387 418 2.6E-8 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Pfam PF01839 FG-GAP repeat 242 280 2.0E-8 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Pfam PF01839 FG-GAP repeat 142 184 1.1E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 PRINTS PR01185 Integrin alpha subunit signature 384 408 4.1E-5 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 PRINTS PR01185 Integrin alpha subunit signature 139 151 4.1E-5 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 PRINTS PR01185 Integrin alpha subunit signature 305 325 4.1E-5 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 SMART SM00191 238 296 2.5E-6 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 SMART SM00191 138 204 5.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 SMART SM00191 75 133 3.0E-5 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 SMART SM00191 3 63 8.9 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 SMART SM00191 308 370 1.3E-6 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 SMART SM00191 382 431 0.0037 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 SUPERFAMILY SSF69318 17 411 2.01E-60 T 28-03-2018 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Gene3D G3DSA:2.60.40.680 90 167 5.5E-13 T 28-03-2018 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Gene3D G3DSA:2.60.40.680 241 322 4.9E-19 T 28-03-2018 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Gene3D G3DSA:2.60.40.680 323 413 8.0E-20 T 28-03-2018 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Gene3D G3DSA:2.60.40.680 168 240 4.5E-4 T 28-03-2018 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Gene3D G3DSA:2.60.40.680 2 89 5.3E-15 T 28-03-2018 SMD44_RS26620 b7a0ac8ecc6373c6eed0d4f7456458e9 455 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 21 98 1.2E-6 T 28-03-2018 SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 129 22.546 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 Gene3D G3DSA:3.30.1390.10 59 129 7.2E-29 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 7 54 3.1E-17 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 SUPERFAMILY SSF48300 5 65 5.89E-14 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 129 1.6E-27 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 102 5.0E-15 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 SUPERFAMILY SSF54736 58 129 2.44E-22 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 Gene3D G3DSA:1.20.5.710 4 58 2.5E-13 T 28-03-2018 SMD44_RS25450 cffeb9930636d2400a2257b7ad026c9c 129 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 129 6.0E-46 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.366.10 1398 1516 3.0E-24 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.366.10 2953 3072 1.2E-27 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.366.10 1215 1347 6.7E-40 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM01294 3704 3771 5.7E-6 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM01294 2146 2213 9.3E-6 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM01294 572 639 2.0E-6 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF47336 2143 2252 3.53E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1218 1514 2.4E-118 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2772 3069 7.4E-128 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF51735 63 263 1.54E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF52151 1403 1498 1.39E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF52151 1215 1339 1.39E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00825 Beta-ketoacyl synthase 2240 2658 6.6E-211 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00825 Beta-ketoacyl synthase 666 1095 9.1E-217 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.30.70.250 2909 2952 1.0E-18 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.30.70.250 1348 1397 7.5E-20 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF00550 Phosphopantetheine attachment site 574 639 1.7E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF00550 Phosphopantetheine attachment site 2147 2213 6.9E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF00550 Phosphopantetheine attachment site 3705 3771 4.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00823 Phosphopantetheine attachment site 2145 2217 5.5E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00823 Phosphopantetheine attachment site 3703 3775 8.4E-33 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00823 Phosphopantetheine attachment site 571 643 7.0E-33 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 ProSitePatterns PS00012 Phosphopantetheine attachment site. 598 613 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:1.10.1200.10 2124 2218 3.8E-19 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF55048 2895 2959 6.41E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.47.10 666 926 7.5E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.47.10 2231 2489 1.8E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF51735 3414 3644 4.3E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:1.10.1200.10 3684 3783 3.2E-20 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF53901 661 1037 2.88E-100 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2238 2478 7.6E-83 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 664 914 2.3E-90 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.366.10 2765 2908 8.1E-51 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2172 2187 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF52151 2960 3055 6.28E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF52151 2769 2896 6.28E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 827 843 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF47336 566 678 3.53E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1043 1154 4.1E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2609 2735 8.7E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF00698 Acyl transferase domain 1216 1533 5.5E-84 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF00698 Acyl transferase domain 2772 3088 2.2E-61 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF55048 1337 1402 2.35E-14 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.47.10 2493 2656 1.3E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.47.10 929 1093 1.1E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF47336 3696 3784 5.76E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2391 2407 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF51735 282 531 1.18E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3730 3745 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:1.10.1200.10 565 665 2.9E-21 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF51735 3187 3399 4.44E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF08659 KR domain 1855 2033 2.2E-58 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF08659 KR domain 3416 3593 3.5E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF08659 KR domain 284 463 7.1E-53 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF51735 1627 1839 3.76E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF53901 2235 2600 1.11E-100 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.50.720 1621 1804 8.4E-4 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 284 464 1.7E-48 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1855 2035 3.4E-48 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3416 3595 3.0E-56 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 SUPERFAMILY SSF51735 1853 2087 1.09E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2486 2603 3.0E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 922 1040 1.4E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.50.720 1847 2108 6.2E-53 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.50.720 277 529 6.2E-46 T 28-03-2018 SMD44_RS36820 8fad581cffa6fb5a52d86b3dd3d9993c 3855 Gene3D G3DSA:3.40.50.720 3409 3667 3.0E-54 T 28-03-2018 SMD44_RS08025 9942497679f050debda1449df3843c18 369 SUPERFAMILY SSF52540 39 268 3.95E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08025 9942497679f050debda1449df3843c18 369 Gene3D G3DSA:3.40.50.300 2 278 1.9E-73 T 28-03-2018 SMD44_RS08025 9942497679f050debda1449df3843c18 369 Pfam PF00005 ABC transporter 44 190 1.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS08025 9942497679f050debda1449df3843c18 369 SMART SM00382 51 240 1.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS08025 9942497679f050debda1449df3843c18 369 SUPERFAMILY SSF54631 237 338 8.92E-5 T 28-03-2018 SMD44_RS08025 9942497679f050debda1449df3843c18 369 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS08025 9942497679f050debda1449df3843c18 369 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 280 5.4E-110 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF46894 128 202 2.79E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:1.10.10.10 140 202 5.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00448 2 115 4.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:3.40.50.2300 1 139 3.4E-31 T 28-03-2018 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF52172 1 127 1.37E-29 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00421 139 196 1.2E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 6.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25805 5e671cd532bc3faaca485869e5a8630e 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 SMART SM00345 37 93 3.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 Pfam PF07702 UTRA domain 114 252 3.2E-34 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 45 93 8.8E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 SUPERFAMILY SSF46785 28 100 1.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 Gene3D G3DSA:1.10.10.10 24 96 5.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 Gene3D G3DSA:3.40.1410.10 97 262 1.2E-42 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 SMART SM00866 113 253 3.2E-35 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 7.4E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 7.4E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15410 710a35c7c407f0c54f607f3d9841134d 262 SUPERFAMILY SSF64288 85 258 2.36E-46 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS13655 eb1b9363272090f0251864b489d62914 363 SMART SM00382 55 248 2.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS13655 eb1b9363272090f0251864b489d62914 363 SUPERFAMILY SSF52540 38 275 1.66E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13655 eb1b9363272090f0251864b489d62914 363 Pfam PF00005 ABC transporter 47 199 1.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS13655 eb1b9363272090f0251864b489d62914 363 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 332 2.4E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS13655 eb1b9363272090f0251864b489d62914 363 Gene3D G3DSA:3.40.50.300 18 348 6.5E-73 T 28-03-2018 SMD44_RS13655 eb1b9363272090f0251864b489d62914 363 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 250 313 3.6E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS13655 eb1b9363272090f0251864b489d62914 363 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 Gene3D G3DSA:3.40.50.880 2 249 1.1E-63 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 Pfam PF01965 DJ-1/PfpI family 5 193 7.4E-24 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 Gene3D G3DSA:1.10.10.60 250 286 4.3E-11 T 28-03-2018 SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 SUPERFAMILY SSF52317 5 213 4.91E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 SUPERFAMILY SSF46689 235 282 1.48E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 Gene3D G3DSA:1.10.10.60 287 339 3.4E-12 T 28-03-2018 SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 SUPERFAMILY SSF46689 285 336 8.06E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 Pfam PF12833 Helix-turn-helix domain 255 334 1.3E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS29940 d040645327bcace77b1c6ca62dd1efa1 339 SMART SM00342 249 332 5.1E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS11185 c17f932d5c075ff54d7a103aacde4df3 210 Gene3D G3DSA:3.90.420.10 15 205 9.0E-46 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS11185 c17f932d5c075ff54d7a103aacde4df3 210 Pfam PF00174 Oxidoreductase molybdopterin binding domain 33 181 8.1E-27 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS11185 c17f932d5c075ff54d7a103aacde4df3 210 SUPERFAMILY SSF56524 16 203 2.75E-52 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS31385 919d254801032c804454d6483f3507f6 496 SUPERFAMILY SSF52540 266 437 1.25E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31385 919d254801032c804454d6483f3507f6 496 Pfam PF16360 GTP-binding GTPase Middle Region 186 269 7.6E-29 T 28-03-2018 IPR032305 GTP-binding protein, middle domain SMD44_RS31385 919d254801032c804454d6483f3507f6 496 Pfam PF13167 GTP-binding GTPase N-terminal 96 184 4.1E-31 T 28-03-2018 IPR025121 GTPase HflX, N-terminal SMD44_RS31385 919d254801032c804454d6483f3507f6 496 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 344 362 1.9E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS31385 919d254801032c804454d6483f3507f6 496 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 277 297 1.9E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS31385 919d254801032c804454d6483f3507f6 496 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 80 435 1.5E-130 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 SMD44_RS31385 919d254801032c804454d6483f3507f6 496 Hamap MF_00900 GTPase HflX [hflX]. 99 465 47.392 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 SMD44_RS31385 919d254801032c804454d6483f3507f6 496 PIRSF PIRSF006809 71 494 2.4E-156 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 SMD44_RS31385 919d254801032c804454d6483f3507f6 496 PIRSF PIRSF006809 29 80 130.0 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 SMD44_RS31385 919d254801032c804454d6483f3507f6 496 Gene3D G3DSA:3.40.50.300 244 446 4.6E-34 T 28-03-2018 SMD44_RS31385 919d254801032c804454d6483f3507f6 496 Pfam PF01926 50S ribosome-binding GTPase 277 395 1.0E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:1.10.1200.10 1705 1805 5.7E-18 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.47.10 1806 2066 8.0E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.47.10 200 470 1.6E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.366.10 744 881 6.9E-44 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF47336 1708 1819 4.45E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF52151 747 871 2.62E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF52151 935 1030 2.62E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.30.70.250 882 929 5.1E-20 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.30.70.250 2484 2530 7.6E-19 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.50.720 2981 3241 2.9E-55 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.50.720 1403 1669 1.6E-51 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF00550 Phosphopantetheine attachment site 113 179 2.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF00550 Phosphopantetheine attachment site 1713 1779 1.3E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF53901 1800 2177 7.69E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1411 1591 5.5E-53 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2989 3169 6.5E-51 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM00823 Phosphopantetheine attachment site 1711 1783 1.4E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM00823 Phosphopantetheine attachment site 111 183 4.4E-32 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF52151 2348 2472 3.4E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF52151 2536 2637 3.4E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF55048 869 934 1.31E-14 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF51735 1160 1376 1.42E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2062 2180 5.5E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 466 583 4.7E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36865 827c983bd9763162275efde65e203360 3275 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 371 387 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 750 1046 4.1E-119 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2351 2645 2.3E-118 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1967 1983 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF55048 2470 2535 1.44E-13 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF00698 Acyl transferase domain 2349 2663 7.5E-83 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF00698 Acyl transferase domain 748 1064 1.9E-83 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.366.10 930 1047 3.7E-25 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.366.10 2531 2651 9.8E-26 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2183 2311 3.4E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 586 710 4.2E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1738 1753 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM01294 112 179 2.1E-6 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM01294 1713 1779 1.5E-4 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF08659 KR domain 1411 1589 1.8E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF08659 KR domain 2989 3167 6.2E-58 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.366.10 2348 2483 4.7E-38 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.50.10090 2783 2930 0.28 T 28-03-2018 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 ProSitePatterns PS00012 Phosphopantetheine attachment site. 138 153 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.47.10 2069 2232 7.5E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:3.40.47.10 473 636 5.2E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM00825 Beta-ketoacyl synthase 210 638 2.6E-224 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SMART SM00825 Beta-ketoacyl synthase 1806 2234 1.8E-213 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF51735 2986 3247 3.77E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF51735 2760 2977 1.26E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF47336 106 223 3.01E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF53901 204 581 8.05E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 208 458 1.6E-90 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1804 2054 3.2E-88 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36865 827c983bd9763162275efde65e203360 3275 SUPERFAMILY SSF51735 1408 1649 3.71E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36865 827c983bd9763162275efde65e203360 3275 Gene3D G3DSA:1.10.1200.10 95 186 4.4E-20 T 28-03-2018 SMD44_RS09055 62ee826040d95b8525d5dcb72b687ac8 120 PIRSF PIRSF005965 1 120 1.4E-41 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS09055 62ee826040d95b8525d5dcb72b687ac8 120 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 118 3.0E-51 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS09055 62ee826040d95b8525d5dcb72b687ac8 120 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 118 1.6E-48 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS09055 62ee826040d95b8525d5dcb72b687ac8 120 Pfam PF07736 Chorismate mutase type I 3 118 6.6E-41 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD44_RS09055 62ee826040d95b8525d5dcb72b687ac8 120 Gene3D G3DSA:3.30.1330.40 3 119 1.9E-43 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS09055 62ee826040d95b8525d5dcb72b687ac8 120 SUPERFAMILY SSF55298 2 118 3.92E-40 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS09260 39e6959165f624062eda5409612dc395 260 Pfam PF07070 SpoOM protein 3 216 2.2E-80 T 28-03-2018 IPR009776 Sporulation stage 0, protein M SMD44_RS31070 bde9e11050d76fec5f3c6d122a49a946 561 SUPERFAMILY SSF56281 19 433 9.52E-96 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS31070 bde9e11050d76fec5f3c6d122a49a946 561 PIRSF PIRSF004803 12 561 9.2E-207 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SMD44_RS31070 bde9e11050d76fec5f3c6d122a49a946 561 Gene3D G3DSA:3.60.15.10 7 457 1.9E-65 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS31070 bde9e11050d76fec5f3c6d122a49a946 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 411 1.2E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain SMD44_RS31070 bde9e11050d76fec5f3c6d122a49a946 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 4.8E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS31070 bde9e11050d76fec5f3c6d122a49a946 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 9.1E-152 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 SMD44_RS31070 bde9e11050d76fec5f3c6d122a49a946 561 SMART SM00849 31 225 3.9E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS31070 bde9e11050d76fec5f3c6d122a49a946 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 41.191 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 Gene3D G3DSA:3.20.20.80 11 284 4.8E-63 T 28-03-2018 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 Pfam PF01301 Glycosyl hydrolases family 35 26 352 2.2E-103 T 28-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 PIRSF PIRSF006336 4 603 8.0E-169 T 28-03-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 SUPERFAMILY SSF49785 471 598 1.87E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 PRINTS PR00742 Glycosyl hydrolase family 35 signature 158 173 1.8E-43 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 PRINTS PR00742 Glycosyl hydrolase family 35 signature 555 571 1.8E-43 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 PRINTS PR00742 Glycosyl hydrolase family 35 signature 103 122 1.8E-43 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 PRINTS PR00742 Glycosyl hydrolase family 35 signature 50 68 1.8E-43 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 PRINTS PR00742 Glycosyl hydrolase family 35 signature 244 259 1.8E-43 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 PRINTS PR00742 Glycosyl hydrolase family 35 signature 29 46 1.8E-43 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 PRINTS PR00742 Glycosyl hydrolase family 35 signature 280 295 1.8E-43 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 Gene3D G3DSA:2.60.120.260 484 604 1.1E-19 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 SUPERFAMILY SSF51445 24 354 6.09E-94 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 Gene3D G3DSA:2.60.120.260 285 483 2.5E-30 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS10595 6c663e2acac8109728e9d4cd50a7bce7 608 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 160 172 - T 28-03-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS04055 103d349b02e34dbed005f1db4b38be97 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.1E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04055 103d349b02e34dbed005f1db4b38be97 199 Gene3D G3DSA:1.10.10.60 1 57 5.6E-17 T 28-03-2018 SMD44_RS04055 103d349b02e34dbed005f1db4b38be97 199 Gene3D G3DSA:1.10.357.10 58 198 6.8E-21 T 28-03-2018 SMD44_RS04055 103d349b02e34dbed005f1db4b38be97 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 6.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04055 103d349b02e34dbed005f1db4b38be97 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04055 103d349b02e34dbed005f1db4b38be97 199 SUPERFAMILY SSF46689 2 68 1.6E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS04055 103d349b02e34dbed005f1db4b38be97 199 SUPERFAMILY SSF48498 82 197 1.25E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS36025 c5e6e05e5f8bfc6e7c08f03f640d3514 298 SMART SM00861 2 168 2.2E-19 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS36025 c5e6e05e5f8bfc6e7c08f03f640d3514 298 Gene3D G3DSA:3.40.50.970 19 174 3.5E-30 T 28-03-2018 SMD44_RS36025 c5e6e05e5f8bfc6e7c08f03f640d3514 298 SUPERFAMILY SSF52922 175 293 1.31E-12 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS36025 c5e6e05e5f8bfc6e7c08f03f640d3514 298 Pfam PF02780 Transketolase, C-terminal domain 178 264 4.4E-6 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SMD44_RS36025 c5e6e05e5f8bfc6e7c08f03f640d3514 298 SUPERFAMILY SSF52518 3 176 4.6E-33 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS36025 c5e6e05e5f8bfc6e7c08f03f640d3514 298 Pfam PF02779 Transketolase, pyrimidine binding domain 3 163 2.0E-21 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS36025 c5e6e05e5f8bfc6e7c08f03f640d3514 298 Gene3D G3DSA:3.40.50.920 175 297 1.5E-17 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS41185 c6c9bcd207d55734377beb030ddad437 350 Gene3D G3DSA:3.40.47.10 23 291 8.1E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41185 c6c9bcd207d55734377beb030ddad437 350 SUPERFAMILY SSF53901 24 197 6.51E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41185 c6c9bcd207d55734377beb030ddad437 350 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 65 221 4.1E-9 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS23350 7f5c044bb46da1feedeae6b8b7acad82 525 Pfam PF00561 alpha/beta hydrolase fold 108 497 1.2E-39 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23350 7f5c044bb46da1feedeae6b8b7acad82 525 SUPERFAMILY SSF53474 205 259 7.28E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23350 7f5c044bb46da1feedeae6b8b7acad82 525 SUPERFAMILY SSF53474 104 160 7.28E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23350 7f5c044bb46da1feedeae6b8b7acad82 525 SUPERFAMILY SSF53474 367 511 7.28E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23350 7f5c044bb46da1feedeae6b8b7acad82 525 Gene3D G3DSA:3.40.50.1820 81 514 2.0E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01155 7d663303d9cb120d3a55904d37ec1530 349 SUPERFAMILY SSF51430 1 317 3.54E-100 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS01155 7d663303d9cb120d3a55904d37ec1530 349 Gene3D G3DSA:3.20.20.100 1 321 2.4E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS01155 7d663303d9cb120d3a55904d37ec1530 349 PRINTS PR00069 Aldo-keto reductase signature 41 65 4.1E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS01155 7d663303d9cb120d3a55904d37ec1530 349 PRINTS PR00069 Aldo-keto reductase signature 105 123 4.1E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS01155 7d663303d9cb120d3a55904d37ec1530 349 PRINTS PR00069 Aldo-keto reductase signature 136 153 4.1E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS01155 7d663303d9cb120d3a55904d37ec1530 349 Pfam PF00248 Aldo/keto reductase family 17 314 1.1E-72 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS05270 7e13f60ce33088cac0f852ea198c0000 417 Pfam PF04030 D-arabinono-1,4-lactone oxidase 286 412 5.7E-17 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 SMD44_RS05270 7e13f60ce33088cac0f852ea198c0000 417 Gene3D G3DSA:3.30.43.10 1 69 2.2E-11 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD44_RS05270 7e13f60ce33088cac0f852ea198c0000 417 PIRSF PIRSF000136 283 416 6.6E-7 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 SMD44_RS05270 7e13f60ce33088cac0f852ea198c0000 417 PIRSF PIRSF000136 2 195 1.1E-34 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 SMD44_RS05270 7e13f60ce33088cac0f852ea198c0000 417 Gene3D G3DSA:3.30.465.10 71 195 6.2E-23 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS05270 7e13f60ce33088cac0f852ea198c0000 417 Pfam PF01565 FAD binding domain 23 151 4.4E-20 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD44_RS05270 7e13f60ce33088cac0f852ea198c0000 417 SUPERFAMILY SSF56176 6 180 2.77E-34 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS33420 3f2bc3fdffe8abcb73285e561a133f45 413 Pfam PF07690 Major Facilitator Superfamily 8 332 3.3E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS33420 3f2bc3fdffe8abcb73285e561a133f45 413 Gene3D G3DSA:1.20.1250.20 3 193 2.3E-25 T 28-03-2018 SMD44_RS33420 3f2bc3fdffe8abcb73285e561a133f45 413 Gene3D G3DSA:1.20.1250.20 194 392 7.1E-17 T 28-03-2018 SMD44_RS33420 3f2bc3fdffe8abcb73285e561a133f45 413 SUPERFAMILY SSF103473 3 381 1.03E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS04685 65c2912aa346de0d8790e36a59228f60 300 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 9 170 1.6E-24 T 28-03-2018 IPR017482 Putative phage-type endonuclease SMD44_RS04685 65c2912aa346de0d8790e36a59228f60 300 SUPERFAMILY SSF52980 8 206 5.36E-25 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS04685 65c2912aa346de0d8790e36a59228f60 300 Pfam PF09588 YqaJ-like viral recombinase domain 11 158 2.0E-17 T 28-03-2018 IPR019080 YqaJ viral recombinase SMD44_RS04685 65c2912aa346de0d8790e36a59228f60 300 Gene3D G3DSA:3.90.320.10 5 224 7.2E-35 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMD44_RS25575 0b639d1e7ecbd9c45dd14a2f526fc55d 132 SUPERFAMILY SSF56047 3 132 1.83E-43 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25575 0b639d1e7ecbd9c45dd14a2f526fc55d 132 Gene3D G3DSA:3.30.1370.30 1 66 4.2E-24 T 28-03-2018 SMD44_RS25575 0b639d1e7ecbd9c45dd14a2f526fc55d 132 Gene3D G3DSA:3.30.1490.10 76 131 1.4E-19 T 28-03-2018 SMD44_RS25575 0b639d1e7ecbd9c45dd14a2f526fc55d 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.37 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25575 0b639d1e7ecbd9c45dd14a2f526fc55d 132 Pfam PF00410 Ribosomal protein S8 5 132 9.9E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS41225 f7a2720c71b92ff4f6a9f2a6b523cc7c 545 Pfam PF00501 AMP-binding enzyme 68 453 2.6E-39 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS41225 f7a2720c71b92ff4f6a9f2a6b523cc7c 545 Gene3D G3DSA:3.30.300.30 458 541 1.4E-4 T 28-03-2018 SMD44_RS41225 f7a2720c71b92ff4f6a9f2a6b523cc7c 545 Gene3D G3DSA:2.30.38.10 366 448 4.9E-11 T 28-03-2018 SMD44_RS41225 f7a2720c71b92ff4f6a9f2a6b523cc7c 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS41225 f7a2720c71b92ff4f6a9f2a6b523cc7c 545 Gene3D G3DSA:3.40.50.980 210 365 2.3E-20 T 28-03-2018 SMD44_RS41225 f7a2720c71b92ff4f6a9f2a6b523cc7c 545 Gene3D G3DSA:3.40.50.980 74 209 2.9E-19 T 28-03-2018 SMD44_RS41225 f7a2720c71b92ff4f6a9f2a6b523cc7c 545 SUPERFAMILY SSF56801 47 540 1.83E-63 T 28-03-2018 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 160 6.1E-11 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 SUPERFAMILY SSF46557 8 82 3.53E-22 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 PIRSF PIRSF006092 4 164 7.8E-31 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 Pfam PF03449 Transcription elongation factor, N-terminal 10 79 4.3E-24 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 53 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 160 3.5E-42 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 SUPERFAMILY SSF54534 84 160 5.1E-10 T 28-03-2018 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 Gene3D G3DSA:1.10.287.180 8 80 2.1E-24 T 28-03-2018 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 161 26.723 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 SMD44_RS27145 80228606fbe8e4f5bd874ea72905d136 165 Gene3D G3DSA:3.10.50.30 81 164 1.1E-14 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SMD44_RS01495 6951567f481b762ace597c5398625328 533 SUPERFAMILY SSF51445 55 436 3.46E-36 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS01495 6951567f481b762ace597c5398625328 533 Pfam PF14587 O-Glycosyl hydrolase family 30 47 292 2.0E-18 T 28-03-2018 SMD44_RS01495 6951567f481b762ace597c5398625328 533 Gene3D G3DSA:2.60.40.1180 430 533 1.7E-22 T 28-03-2018 SMD44_RS01495 6951567f481b762ace597c5398625328 533 Gene3D G3DSA:3.20.20.80 53 429 1.6E-83 T 28-03-2018 SMD44_RS37630 7cfe48cbfd690e4ba0e649dcf32bd38c 233 SUPERFAMILY SSF50965 25 174 5.23E-14 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller SMD44_RS37630 7cfe48cbfd690e4ba0e649dcf32bd38c 233 Gene3D G3DSA:2.130.10.80 15 206 7.8E-28 T 28-03-2018 IPR015916 Galactose oxidase, beta-propeller SMD44_RS38415 b43c60de5ef364f63c71d3419efbff53 301 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 255 290 8.4E-10 T 28-03-2018 SMD44_RS38415 b43c60de5ef364f63c71d3419efbff53 301 SUPERFAMILY SSF51695 58 294 6.8E-15 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS38415 b43c60de5ef364f63c71d3419efbff53 301 Gene3D G3DSA:3.20.20.190 45 297 2.7E-21 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 Gene3D G3DSA:3.40.50.720 118 289 1.4E-57 T 28-03-2018 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 SUPERFAMILY SSF55021 459 530 1.25E-15 T 28-03-2018 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 11 531 1.1E-189 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 Pfam PF01842 ACT domain 459 520 3.0E-11 T 28-03-2018 IPR002912 ACT domain SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 Gene3D G3DSA:3.30.1330.90 320 457 5.6E-31 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 SUPERFAMILY SSF51735 107 286 6.86E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 SUPERFAMILY SSF52283 8 140 2.65E-37 T 28-03-2018 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 Gene3D G3DSA:3.40.50.720 8 117 4.1E-32 T 28-03-2018 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 SUPERFAMILY SSF143548 325 454 3.66E-34 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 318 8.6E-34 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 286 1.5E-62 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD44_RS29925 b64a4b4631d65667e3a09c5545e4e761 534 Gene3D G3DSA:3.30.70.260 458 533 2.6E-17 T 28-03-2018 SMD44_RS01835 b6365f8940da7ee1135b81bcaa92b7e4 206 Gene3D G3DSA:1.10.357.10 70 206 4.8E-19 T 28-03-2018 SMD44_RS01835 b6365f8940da7ee1135b81bcaa92b7e4 206 Gene3D G3DSA:1.10.10.60 1 69 1.8E-21 T 28-03-2018 SMD44_RS01835 b6365f8940da7ee1135b81bcaa92b7e4 206 SUPERFAMILY SSF46689 12 92 2.54E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01835 b6365f8940da7ee1135b81bcaa92b7e4 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.4E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS01835 b6365f8940da7ee1135b81bcaa92b7e4 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS01835 b6365f8940da7ee1135b81bcaa92b7e4 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS01835 b6365f8940da7ee1135b81bcaa92b7e4 206 SUPERFAMILY SSF48498 91 203 2.59E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS31695 c109de3d3a50acbf4faa4591247149dc 424 SUPERFAMILY SSF103473 17 391 1.31E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS31695 c109de3d3a50acbf4faa4591247149dc 424 Gene3D G3DSA:1.20.1250.20 207 402 9.9E-19 T 28-03-2018 SMD44_RS31695 c109de3d3a50acbf4faa4591247149dc 424 Pfam PF07690 Major Facilitator Superfamily 20 291 2.6E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS31695 c109de3d3a50acbf4faa4591247149dc 424 Gene3D G3DSA:1.20.1250.20 3 202 7.5E-11 T 28-03-2018 SMD44_RS25185 b3ea427f09b392db4d1a34eb3bc04300 137 Gene3D G3DSA:2.60.120.10 8 121 1.9E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS25185 b3ea427f09b392db4d1a34eb3bc04300 137 Pfam PF07883 Cupin domain 45 104 7.9E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS25185 b3ea427f09b392db4d1a34eb3bc04300 137 SUPERFAMILY SSF51182 11 128 1.64E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS15895 1f71375ef7e9c653c74770072f7cc33f 300 Gene3D G3DSA:3.30.43.10 17 63 2.4E-12 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD44_RS15895 1f71375ef7e9c653c74770072f7cc33f 300 Gene3D G3DSA:3.30.390.50 181 300 2.1E-24 T 28-03-2018 SMD44_RS15895 1f71375ef7e9c653c74770072f7cc33f 300 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 15 178 2.3E-40 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMD44_RS15895 1f71375ef7e9c653c74770072f7cc33f 300 SUPERFAMILY SSF55447 184 235 1.88E-5 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD44_RS15895 1f71375ef7e9c653c74770072f7cc33f 300 SUPERFAMILY SSF56176 11 178 3.09E-40 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS15895 1f71375ef7e9c653c74770072f7cc33f 300 Gene3D G3DSA:3.30.465.10 66 178 1.9E-26 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 201 211 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 351 361 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 Pfam PF00082 Subtilase family 159 389 7.5E-39 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 SUPERFAMILY SSF52743 135 410 3.53E-74 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 Pfam PF05922 Peptidase inhibitor I9 59 125 1.8E-7 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 SUPERFAMILY SSF49785 424 527 3.83E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 Gene3D G3DSA:3.30.70.80 49 130 1.9E-17 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 SUPERFAMILY SSF54897 57 125 3.63E-9 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 164 175 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 Gene3D G3DSA:3.40.50.200 131 408 4.5E-76 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 Gene3D G3DSA:2.60.120.260 415 527 1.2E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 Pfam PF01483 Proprotein convertase P-domain 448 527 3.1E-18 T 28-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 197 210 2.9E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 350 366 2.9E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS27605 709e881dcc5a3385cffdb13677a07f0c 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 159 178 2.9E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 SUPERFAMILY SSF46689 248 298 3.4E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 Gene3D G3DSA:1.10.10.60 215 254 4.0E-13 T 28-03-2018 SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 SUPERFAMILY SSF46689 194 246 2.21E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 Gene3D G3DSA:3.40.50.880 1 214 3.2E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 SMART SM00342 212 295 5.1E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 Pfam PF01965 DJ-1/PfpI family 52 156 3.0E-11 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 SUPERFAMILY SSF52317 4 177 3.97E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 249 291 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 Gene3D G3DSA:1.10.10.60 255 299 4.5E-10 T 28-03-2018 SMD44_RS01405 50cc6b0a144957aca3d257ddd136fc29 302 Pfam PF12833 Helix-turn-helix domain 218 296 5.3E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS19985 00b62827aa0837255a2363cc1dee2941 87 SUPERFAMILY SSF82697 3 81 5.23E-26 T 28-03-2018 SMD44_RS19985 00b62827aa0837255a2363cc1dee2941 87 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 81 6.1E-22 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19985 00b62827aa0837255a2363cc1dee2941 87 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 75 2.0E-30 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19985 00b62827aa0837255a2363cc1dee2941 87 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 78 2.1E-28 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19985 00b62827aa0837255a2363cc1dee2941 87 Gene3D G3DSA:3.30.1280.10 1 80 2.7E-29 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19985 00b62827aa0837255a2363cc1dee2941 87 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 21.971 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS06945 ee0532f019d901923e18be9ee9c391d2 222 Gene3D G3DSA:1.10.357.10 78 212 5.4E-17 T 28-03-2018 SMD44_RS06945 ee0532f019d901923e18be9ee9c391d2 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 74 8.3E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06945 ee0532f019d901923e18be9ee9c391d2 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06945 ee0532f019d901923e18be9ee9c391d2 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06945 ee0532f019d901923e18be9ee9c391d2 222 Gene3D G3DSA:1.10.10.60 2 77 3.3E-18 T 28-03-2018 SMD44_RS06945 ee0532f019d901923e18be9ee9c391d2 222 SUPERFAMILY SSF46689 24 93 2.14E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS06945 ee0532f019d901923e18be9ee9c391d2 222 SUPERFAMILY SSF48498 99 201 7.23E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 Gene3D G3DSA:3.40.50.720 5 48 2.9E-10 T 28-03-2018 SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 Gene3D G3DSA:3.40.50.720 49 255 3.7E-58 T 28-03-2018 SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 4.0E-57 T 28-03-2018 SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.2E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 7.2E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 7.2E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 7.2E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 7.2E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.2E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS34975 6b9c4d853cebcd7d086704e4ddb7d341 255 SUPERFAMILY SSF51735 12 250 5.11E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS10895 2a60b23fd02aa0c11d2e4bfebe4f9bba 321 Pfam PF00005 ABC transporter 28 169 1.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS10895 2a60b23fd02aa0c11d2e4bfebe4f9bba 321 SUPERFAMILY SSF52540 21 233 2.82E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10895 2a60b23fd02aa0c11d2e4bfebe4f9bba 321 Gene3D G3DSA:3.40.50.300 1 278 4.2E-60 T 28-03-2018 SMD44_RS10895 2a60b23fd02aa0c11d2e4bfebe4f9bba 321 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS10895 2a60b23fd02aa0c11d2e4bfebe4f9bba 321 SMART SM00382 35 219 2.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19430 e23f34517b03b833a5eb3bff7b12dda1 234 Pfam PF01569 PAP2 superfamily 77 180 9.5E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS19430 e23f34517b03b833a5eb3bff7b12dda1 234 Gene3D G3DSA:1.20.144.10 4 197 9.4E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS19430 e23f34517b03b833a5eb3bff7b12dda1 234 SUPERFAMILY SSF48317 9 183 1.28E-33 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS19430 e23f34517b03b833a5eb3bff7b12dda1 234 SMART SM00014 70 181 7.3E-11 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS21550 01836b760ae94899fce4c51ba4b07cd3 852 SUPERFAMILY SSF56801 473 795 4.71E-25 T 28-03-2018 SMD44_RS21550 01836b760ae94899fce4c51ba4b07cd3 852 Pfam PF00501 AMP-binding enzyme 566 690 3.8E-5 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS21550 01836b760ae94899fce4c51ba4b07cd3 852 SUPERFAMILY SSF53720 56 303 8.25E-17 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS21550 01836b760ae94899fce4c51ba4b07cd3 852 Gene3D G3DSA:3.40.605.10 31 279 6.5E-20 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS21550 01836b760ae94899fce4c51ba4b07cd3 852 Gene3D G3DSA:3.40.50.980 473 655 4.8E-16 T 28-03-2018 SMD44_RS21550 01836b760ae94899fce4c51ba4b07cd3 852 Pfam PF05893 Acyl-CoA reductase (LuxC) 38 436 8.1E-81 T 28-03-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 SMD44_RS14800 2662ac815f9400f36e3ea0f2da9ba612 283 Pfam PF01261 Xylose isomerase-like TIM barrel 28 233 2.9E-31 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS14800 2662ac815f9400f36e3ea0f2da9ba612 283 SUPERFAMILY SSF51658 12 279 4.45E-58 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS14800 2662ac815f9400f36e3ea0f2da9ba612 283 Gene3D G3DSA:3.20.20.150 7 282 1.8E-52 T 28-03-2018 SMD44_RS00780 894e4c7a541d0a62731692044a988714 138 Pfam PF07876 Stress responsive A/B Barrel Domain 2 91 9.9E-11 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel SMD44_RS00780 894e4c7a541d0a62731692044a988714 138 Gene3D G3DSA:3.30.70.100 1 94 3.8E-10 T 28-03-2018 SMD44_RS00780 894e4c7a541d0a62731692044a988714 138 SMART SM00886 2 93 1.6E-12 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel SMD44_RS00780 894e4c7a541d0a62731692044a988714 138 SUPERFAMILY SSF54909 1 91 5.5E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS17055 26434d965ba19ae65f56946bc62921d6 207 SUPERFAMILY SSF52980 24 180 6.97E-18 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS17055 26434d965ba19ae65f56946bc62921d6 207 Pfam PF05685 Putative restriction endonuclease 33 186 2.3E-23 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS17055 26434d965ba19ae65f56946bc62921d6 207 Gene3D G3DSA:3.90.1570.10 25 207 1.7E-29 T 28-03-2018 SMD44_RS33495 f41bf5972d44a5ef6438d96afd4f8034 215 Gene3D G3DSA:1.10.10.10 3 202 9.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33495 f41bf5972d44a5ef6438d96afd4f8034 215 SUPERFAMILY SSF55718 135 212 3.24E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS33495 f41bf5972d44a5ef6438d96afd4f8034 215 SUPERFAMILY SSF46785 9 110 2.42E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33495 f41bf5972d44a5ef6438d96afd4f8034 215 Pfam PF01638 HxlR-like helix-turn-helix 22 107 1.3E-21 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 234 41.792 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 SMART SM00855 7 193 4.2E-22 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 SUPERFAMILY SSF53254 6 225 4.28E-69 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 PIRSF PIRSF000709 148 222 1.8 T 28-03-2018 SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 PIRSF PIRSF000709 4 113 3.0E-4 T 28-03-2018 SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 Gene3D G3DSA:3.40.50.1240 5 253 1.4E-57 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 251 3.2E-110 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SMD44_RS19045 3f065d6befa92e74653dba88df5ebf96 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 136 1.4E-26 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS27405 74d73b3888988278f1ee3d47d73254cc 256 SUPERFAMILY SSF53335 40 255 5.57E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS27405 74d73b3888988278f1ee3d47d73254cc 256 Pfam PF08241 Methyltransferase domain 57 144 1.4E-5 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS27405 74d73b3888988278f1ee3d47d73254cc 256 Gene3D G3DSA:3.40.50.150 42 250 2.0E-12 T 28-03-2018 SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 SMART SM00851 29 143 8.9E-49 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 Gene3D G3DSA:3.40.50.1380 5 205 1.9E-67 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 SUPERFAMILY SSF52335 16 205 3.4E-65 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 PIRSF PIRSF000414 11 527 1.3E-194 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 SUPERFAMILY SSF53927 225 527 3.71E-117 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 17 527 42.043 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 Gene3D G3DSA:3.40.140.20 242 372 7.3E-51 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 Pfam PF02142 MGS-like domain 30 142 2.0E-23 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 SMART SM00798 148 461 1.2E-181 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 Pfam PF01808 AICARFT/IMPCHase bienzyme 148 460 3.2E-111 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 18 527 1.8E-169 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS26040 adb3bbba25e517948c51a3b70095f136 527 Gene3D G3DSA:3.40.140.20 373 517 2.3E-48 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS41010 be406adee11efef69e642475f8556890 314 Gene3D G3DSA:3.20.10.10 139 292 1.6E-49 T 28-03-2018 SMD44_RS41010 be406adee11efef69e642475f8556890 314 Pfam PF01063 Amino-transferase class IV 37 263 5.6E-49 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS41010 be406adee11efef69e642475f8556890 314 Gene3D G3DSA:3.30.470.10 2 138 7.0E-31 T 28-03-2018 SMD44_RS41010 be406adee11efef69e642475f8556890 314 ProSitePatterns PS00770 Aminotransferases class-IV signature. 190 219 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS41010 be406adee11efef69e642475f8556890 314 SUPERFAMILY SSF56752 9 303 1.12E-89 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS41010 be406adee11efef69e642475f8556890 314 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 303 1.5E-93 T 28-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 SMD44_RS27825 a27e89e9b5fd4bad0ed1e76f0e68afa5 249 Pfam PF03641 Possible lysine decarboxylase 113 241 4.3E-33 T 28-03-2018 IPR031100 LOG family SMD44_RS27825 a27e89e9b5fd4bad0ed1e76f0e68afa5 249 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 71 244 2.7E-41 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG SMD44_RS27825 a27e89e9b5fd4bad0ed1e76f0e68afa5 249 SUPERFAMILY SSF102405 42 242 4.73E-61 T 28-03-2018 SMD44_RS27825 a27e89e9b5fd4bad0ed1e76f0e68afa5 249 Gene3D G3DSA:3.40.50.450 47 249 1.4E-64 T 28-03-2018 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 Gene3D G3DSA:1.10.630.10 2 402 2.7E-69 T 28-03-2018 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 SUPERFAMILY SSF48264 7 401 2.62E-90 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 Pfam PF00067 Cytochrome P450 189 374 1.4E-20 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 324 339 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 354 365 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 154 169 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 197 219 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 91 102 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 279 290 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 296 323 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 137 153 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS22645 a8b44784123f78f38783955ffbaddb78 402 PRINTS PR00359 B-class P450 signature 345 354 5.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07375 6506a3c9f2bb856814f38700166fe0e2 231 SMART SM00756 45 186 1.8E-57 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMD44_RS07375 6506a3c9f2bb856814f38700166fe0e2 231 Pfam PF07884 Vitamin K epoxide reductase family 51 182 8.6E-30 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMD44_RS08035 a153239aa9ae9666dbf184627282a320 279 SUPERFAMILY SSF63380 9 136 8.61E-12 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS08035 a153239aa9ae9666dbf184627282a320 279 Pfam PF04954 Siderophore-interacting protein 138 253 1.5E-37 T 28-03-2018 IPR007037 Siderophore-interacting protein SMD44_RS08035 a153239aa9ae9666dbf184627282a320 279 Pfam PF08021 Siderophore-interacting FAD-binding domain 16 131 6.1E-38 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SMD44_RS08035 a153239aa9ae9666dbf184627282a320 279 Gene3D G3DSA:2.40.30.10 5 131 5.4E-34 T 28-03-2018 SMD44_RS08035 a153239aa9ae9666dbf184627282a320 279 Gene3D G3DSA:3.40.50.80 132 275 1.0E-46 T 28-03-2018 SMD44_RS05940 2fd237b58352e85c24946a64ec487013 385 Gene3D G3DSA:3.30.565.10 262 385 2.1E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05940 2fd237b58352e85c24946a64ec487013 385 Pfam PF07730 Histidine kinase 199 264 1.8E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS05940 2fd237b58352e85c24946a64ec487013 385 SUPERFAMILY SSF55874 272 383 1.78E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05940 2fd237b58352e85c24946a64ec487013 385 SMART SM00387 297 385 3.1E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22095 423072445ad3a8fdafc85fd004e37302 90 Pfam PF14408 Ribosomally synthesised peptide in actinomycetes 34 84 5.6E-10 T 28-03-2018 IPR025843 Ribosomally synthesized peptide in Actinomycetes SMD44_RS22095 423072445ad3a8fdafc85fd004e37302 90 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 14 90 4.0E-13 T 28-03-2018 IPR026496 Putative ATP-grasp target RiPP SMD44_RS29990 0f1b979f8a4ef2c5b7c44107f68552ea 194 Pfam PF13527 Acetyltransferase (GNAT) domain 33 149 2.9E-12 T 28-03-2018 SMD44_RS29990 0f1b979f8a4ef2c5b7c44107f68552ea 194 SUPERFAMILY SSF55729 29 191 2.88E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS29990 0f1b979f8a4ef2c5b7c44107f68552ea 194 Gene3D G3DSA:3.40.630.30 19 194 6.0E-27 T 28-03-2018 SMD44_RS29280 b54f60221b2cb63f761befde8597fc3d 704 Gene3D G3DSA:3.20.20.80 324 589 1.5E-20 T 28-03-2018 SMD44_RS29280 b54f60221b2cb63f761befde8597fc3d 704 Pfam PF13560 Helix-turn-helix domain 102 165 2.9E-12 T 28-03-2018 SMD44_RS29280 b54f60221b2cb63f761befde8597fc3d 704 Gene3D G3DSA:1.10.260.40 93 181 2.0E-9 T 28-03-2018 SMD44_RS29280 b54f60221b2cb63f761befde8597fc3d 704 SUPERFAMILY SSF51445 327 608 5.58E-29 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS29280 b54f60221b2cb63f761befde8597fc3d 704 SUPERFAMILY SSF47413 97 162 7.29E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS29280 b54f60221b2cb63f761befde8597fc3d 704 SMART SM00530 106 162 6.7E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS12870 2d2dd937b16d8074db5247480f677370 1559 Pfam PF11847 Domain of unknown function (DUF3367) 39 693 1.0E-221 T 28-03-2018 IPR021798 Protein of unknown function DUF3367 MetaCyc: PWY-6397 SMD44_RS12870 2d2dd937b16d8074db5247480f677370 1559 Gene3D G3DSA:2.60.120.260 710 859 1.5E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS12870 2d2dd937b16d8074db5247480f677370 1559 Gene3D G3DSA:2.60.120.260 938 1061 1.3E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS12870 2d2dd937b16d8074db5247480f677370 1559 SUPERFAMILY SSF49785 720 855 1.16E-6 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS17460 b8d9138b7e3403e3822181b45f86af0f 516 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 269 276 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS17460 b8d9138b7e3403e3822181b45f86af0f 516 Gene3D G3DSA:3.40.309.10 286 485 2.2E-57 T 28-03-2018 SMD44_RS17460 b8d9138b7e3403e3822181b45f86af0f 516 SUPERFAMILY SSF53720 34 504 5.24E-139 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS17460 b8d9138b7e3403e3822181b45f86af0f 516 Pfam PF00171 Aldehyde dehydrogenase family 40 496 5.3E-135 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS17460 b8d9138b7e3403e3822181b45f86af0f 516 Gene3D G3DSA:3.40.605.10 26 285 4.6E-77 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS30090 c4439fa02e743eadc63d1754087df345 541 SUPERFAMILY SSF51569 15 306 3.48E-76 T 28-03-2018 SMD44_RS30090 c4439fa02e743eadc63d1754087df345 541 SMART SM00917 389 532 2.0E-39 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS30090 c4439fa02e743eadc63d1754087df345 541 Pfam PF00682 HMGL-like 19 281 2.8E-45 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMD44_RS30090 c4439fa02e743eadc63d1754087df345 541 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 18 535 3.2E-195 T 28-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 SMD44_RS30090 c4439fa02e743eadc63d1754087df345 541 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 25 41 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS30090 c4439fa02e743eadc63d1754087df345 541 SUPERFAMILY SSF110921 414 528 2.75E-22 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS30090 c4439fa02e743eadc63d1754087df345 541 Pfam PF08502 LeuA allosteric (dimerisation) domain 389 530 3.3E-27 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS30090 c4439fa02e743eadc63d1754087df345 541 Gene3D G3DSA:3.20.20.70 2 364 3.9E-99 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS29770 224ba21083fb28e3c78851d182f0093a 237 SUPERFAMILY SSF55846 78 223 5.23E-40 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS29770 224ba21083fb28e3c78851d182f0093a 237 Gene3D G3DSA:3.40.80.10 55 229 6.9E-39 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS29770 224ba21083fb28e3c78851d182f0093a 237 SMART SM00644 79 208 8.1E-36 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS29770 224ba21083fb28e3c78851d182f0093a 237 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 88 209 3.8E-28 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 9.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 9.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 9.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 Gene3D G3DSA:3.40.50.2300 5 137 1.4E-37 T 28-03-2018 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 Gene3D G3DSA:1.10.10.10 138 217 3.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 209 8.6E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 SMART SM00448 6 119 4.4E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 SUPERFAMILY SSF52172 6 135 1.71E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 SUPERFAMILY SSF46894 150 218 6.46E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 Pfam PF00072 Response regulator receiver domain 8 118 2.9E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS36940 3ad96e3e1511cf98a2fab5f3487aea40 220 SMART SM00421 155 212 1.4E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.0E-54 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 7.6E-38 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 7.6E-38 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 7.6E-38 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 7.6E-38 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.938 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 Gene3D G3DSA:3.90.1170.10 3 139 3.2E-51 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.1E-48 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25535 11cc00740a656a31ac36b1d013a47d0e 139 SUPERFAMILY SSF54686 1 135 1.07E-55 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMD44_RS42430 ab5695e7af4350863ee72d9303e29834 93 SMART SM00411 1 91 1.9E-36 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS42430 ab5695e7af4350863ee72d9303e29834 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SMD44_RS42430 ab5695e7af4350863ee72d9303e29834 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 7.3E-8 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS42430 ab5695e7af4350863ee72d9303e29834 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 7.3E-8 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS42430 ab5695e7af4350863ee72d9303e29834 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 7.3E-8 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS42430 ab5695e7af4350863ee72d9303e29834 93 Gene3D G3DSA:4.10.520.10 1 93 7.2E-28 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD44_RS42430 ab5695e7af4350863ee72d9303e29834 93 SUPERFAMILY SSF47729 1 91 1.91E-25 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD44_RS42430 ab5695e7af4350863ee72d9303e29834 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.0E-26 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1251 1293 2.5E-4 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 969 1010 1.9E-6 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 783 820 2.3E-6 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 897 934 2.2E-8 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 527 567 3.2E-4 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1104 1144 0.0011 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 829 854 2.6E-4 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1045 1068 0.0027 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 876 916 1.4E-7 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1473 1501 9.8E-4 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 855 894 2.3E-4 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1146 1184 9.9E-5 T 28-03-2018 IPR006530 YD repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 855 891 4.7E-8 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 783 820 2.4E-7 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 1032 1068 6.1E-5 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 990 1023 4.6E-8 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 1125 1157 3.5E-6 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 836 867 4.7E-5 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 897 933 9.7E-8 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 1251 1288 1.0E-5 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 969 1002 6.3E-7 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 Pfam PF05593 RHS Repeat 762 798 2.8E-7 T 28-03-2018 IPR031325 RHS repeat SMD44_RS43710 bb409f06eb9633b44b9d90b8a0f6d41f 1910 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1583 1667 8.0E-15 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 SMD44_RS41440 5e3d9ee9b0ecd55a79613c6a9ab04a9b 159 SUPERFAMILY SSF69118 20 151 6.98E-30 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS41440 5e3d9ee9b0ecd55a79613c6a9ab04a9b 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 102 3.8E-6 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS41440 5e3d9ee9b0ecd55a79613c6a9ab04a9b 159 Gene3D G3DSA:1.20.1290.10 16 152 2.1E-26 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 SUPERFAMILY SSF52317 1 188 1.39E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 SUPERFAMILY SSF46689 210 259 1.01E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 Pfam PF12833 Helix-turn-helix domain 231 309 2.9E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 Gene3D G3DSA:1.10.10.60 264 316 6.8E-14 T 28-03-2018 SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 304 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 SMART SM00342 225 308 5.0E-33 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 SUPERFAMILY SSF46689 262 311 2.94E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 Gene3D G3DSA:1.10.10.60 217 263 1.2E-15 T 28-03-2018 SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 Gene3D G3DSA:3.40.50.880 2 216 6.0E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS05365 7b3a1037ac43a17df6cb7fc7be134f68 316 Pfam PF01965 DJ-1/PfpI family 3 169 7.7E-17 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 Gene3D G3DSA:3.50.50.60 4 68 0.0022 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 SUPERFAMILY SSF48179 184 330 2.89E-68 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 PIRSF PIRSF000116 4 325 4.9E-49 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 SUPERFAMILY SSF51735 3 183 2.4E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 Gene3D G3DSA:1.10.1040.10 69 331 2.1E-111 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 1.7E-76 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 1.2E-131 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 329 44.351 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD44_RS29920 208d1371768017f0771e8f9c71733c93 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 5.3E-64 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD44_RS41615 8e6f8e7f8c105bb2daed1990b2e78dc4 212 SUPERFAMILY SSF48498 99 178 8.07E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS41615 8e6f8e7f8c105bb2daed1990b2e78dc4 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 8.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS41615 8e6f8e7f8c105bb2daed1990b2e78dc4 212 Gene3D G3DSA:1.10.10.60 1 63 1.6E-12 T 28-03-2018 SMD44_RS41615 8e6f8e7f8c105bb2daed1990b2e78dc4 212 SUPERFAMILY SSF46689 10 79 3.08E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS41615 8e6f8e7f8c105bb2daed1990b2e78dc4 212 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 108 175 2.1E-9 T 28-03-2018 SMD44_RS41615 8e6f8e7f8c105bb2daed1990b2e78dc4 212 Gene3D G3DSA:1.10.357.10 64 203 3.1E-15 T 28-03-2018 SMD44_RS13755 49a097fb76d5f086151b0a06a5ff6b0f 333 SUPERFAMILY SSF51556 4 312 1.33E-79 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS13755 49a097fb76d5f086151b0a06a5ff6b0f 333 Hamap MF_01962 Adenine deaminase. 1 311 80.316 T 28-03-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 SMD44_RS13755 49a097fb76d5f086151b0a06a5ff6b0f 333 Pfam PF00962 Adenosine/AMP deaminase 3 311 3.1E-70 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMD44_RS13755 49a097fb76d5f086151b0a06a5ff6b0f 333 Gene3D G3DSA:3.20.20.140 1 333 2.5E-77 T 28-03-2018 SMD44_RS13755 49a097fb76d5f086151b0a06a5ff6b0f 333 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 3 312 4.3E-109 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMD44_RS06845 97fc1c2618292ae069710736b2bdd38a 376 Gene3D G3DSA:3.40.50.2000 192 350 1.8E-36 T 28-03-2018 SMD44_RS06845 97fc1c2618292ae069710736b2bdd38a 376 SUPERFAMILY SSF53756 1 368 1.54E-75 T 28-03-2018 SMD44_RS06845 97fc1c2618292ae069710736b2bdd38a 376 Pfam PF13439 Glycosyltransferase Family 4 14 183 1.3E-25 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS06845 97fc1c2618292ae069710736b2bdd38a 376 Pfam PF00534 Glycosyl transferases group 1 197 345 2.9E-23 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS06845 97fc1c2618292ae069710736b2bdd38a 376 Gene3D G3DSA:3.40.50.2000 1 191 2.9E-20 T 28-03-2018 SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 SUPERFAMILY SSF49785 317 493 8.5E-45 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 361 452 3.5E-12 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 SUPERFAMILY SSF56988 42 269 5.36E-54 T 28-03-2018 SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 631 741 1.3E-8 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 SUPERFAMILY SSF49303 500 591 3.45E-10 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 Gene3D G3DSA:2.60.120.260 299 495 1.2E-43 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 SUPERFAMILY SSF51445 587 864 3.99E-61 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 Gene3D G3DSA:2.60.40.10 496 591 2.1E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 Pfam PF07691 PA14 domain 43 183 1.2E-25 T 28-03-2018 IPR011658 PA14 domain SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 SMART SM00758 41 183 8.1E-42 T 28-03-2018 IPR011658 PA14 domain SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 Gene3D G3DSA:3.90.182.10 27 298 3.2E-39 T 28-03-2018 SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 Gene3D G3DSA:3.20.20.80 596 865 2.5E-38 T 28-03-2018 SMD44_RS37065 e5d86d848f697db766da21da48f971b2 881 Pfam PF00703 Glycosyl hydrolases family 2 526 590 6.3E-9 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMD44_RS28965 76d362e86c5845b763cbea3f24e49916 223 Gene3D G3DSA:3.40.1350.10 101 220 0.0014 T 28-03-2018 SMD44_RS28965 76d362e86c5845b763cbea3f24e49916 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 215 31.514 T 28-03-2018 IPR002793 Endonuclease NucS SMD44_RS28965 76d362e86c5845b763cbea3f24e49916 223 Pfam PF01939 Endonuclease NucS 2 223 2.2E-85 T 28-03-2018 IPR002793 Endonuclease NucS SMD44_RS03360 bf3436b60f3c31347ca87091ea06aae0 465 Gene3D G3DSA:3.50.50.60 26 230 6.0E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03360 bf3436b60f3c31347ca87091ea06aae0 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 191 209 2.1E-5 T 28-03-2018 SMD44_RS03360 bf3436b60f3c31347ca87091ea06aae0 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 254 2.1E-5 T 28-03-2018 SMD44_RS03360 bf3436b60f3c31347ca87091ea06aae0 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 38 57 2.1E-5 T 28-03-2018 SMD44_RS03360 bf3436b60f3c31347ca87091ea06aae0 465 SUPERFAMILY SSF51905 35 259 4.17E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03360 bf3436b60f3c31347ca87091ea06aae0 465 Gene3D G3DSA:3.50.50.60 233 465 4.0E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03360 bf3436b60f3c31347ca87091ea06aae0 465 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 35 383 1.7E-105 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD44_RS03360 bf3436b60f3c31347ca87091ea06aae0 465 SUPERFAMILY SSF51905 180 388 6.28E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS21565 eb8b083f5ced928bd34ae5042fe7194b 411 SUPERFAMILY SSF103473 78 393 7.19E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS21565 eb8b083f5ced928bd34ae5042fe7194b 411 Gene3D G3DSA:1.20.1250.20 1 207 5.0E-12 T 28-03-2018 SMD44_RS21565 eb8b083f5ced928bd34ae5042fe7194b 411 Pfam PF05977 Transmembrane secretion effector 3 393 7.8E-16 T 28-03-2018 IPR010290 Transmembrane secretion effector SMD44_RS21565 eb8b083f5ced928bd34ae5042fe7194b 411 Gene3D G3DSA:1.20.1250.20 208 395 8.3E-13 T 28-03-2018 SMD44_RS23345 e3cf3e85039c7ba55d6de734bced45bf 401 SUPERFAMILY SSF52540 4 227 2.2E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23345 e3cf3e85039c7ba55d6de734bced45bf 401 Gene3D G3DSA:3.40.50.300 4 189 1.2E-24 T 28-03-2018 SMD44_RS23345 e3cf3e85039c7ba55d6de734bced45bf 401 Gene3D G3DSA:1.20.272.10 301 400 7.2E-25 T 28-03-2018 SMD44_RS23345 e3cf3e85039c7ba55d6de734bced45bf 401 Pfam PF13177 DNA polymerase III, delta subunit 39 188 2.8E-34 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 Gene3D G3DSA:3.30.390.30 358 480 2.6E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 SUPERFAMILY SSF51905 9 341 2.45E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 Gene3D G3DSA:3.50.50.60 165 285 1.3E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 365 471 1.5E-21 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 157 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 427 442 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 46 61 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 449 469 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 361 382 7.0E-52 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PIRSF PIRSF000350 1 477 5.1E-68 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 SUPERFAMILY SSF55424 361 478 2.58E-26 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 Gene3D G3DSA:3.50.50.60 286 357 0.0012 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 326 8.5E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 Gene3D G3DSA:3.50.50.60 9 164 4.7E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 1.1E-21 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.1E-21 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 1.1E-21 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 1.1E-21 T 28-03-2018 SMD44_RS37515 ac868d6ff85e01316319d489573e4bde 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 202 1.1E-21 T 28-03-2018 SMD44_RS28465 dbb3c02e19dcac9e266d2ed3f392cb87 199 Gene3D G3DSA:3.40.430.10 3 194 5.3E-34 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS28465 dbb3c02e19dcac9e266d2ed3f392cb87 199 Pfam PF01872 RibD C-terminal domain 2 189 1.0E-12 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS28465 dbb3c02e19dcac9e266d2ed3f392cb87 199 SUPERFAMILY SSF53597 2 195 2.09E-28 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS30190 62e6ebe872ec813e07e4e4131990ffdb 1302 SUPERFAMILY SSF55874 546 666 5.63E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS30190 62e6ebe872ec813e07e4e4131990ffdb 1302 SMART SM00387 558 669 1.5E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS30190 62e6ebe872ec813e07e4e4131990ffdb 1302 Pfam PF00672 HAMP domain 376 443 1.8E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS30190 62e6ebe872ec813e07e4e4131990ffdb 1302 Pfam PF08376 Nitrate and nitrite sensing 88 338 3.4E-41 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein SMD44_RS30190 62e6ebe872ec813e07e4e4131990ffdb 1302 Gene3D G3DSA:1.10.510.10 794 1114 5.8E-4 T 28-03-2018 SMD44_RS30190 62e6ebe872ec813e07e4e4131990ffdb 1302 SMART SM00304 376 446 8.5E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS30190 62e6ebe872ec813e07e4e4131990ffdb 1302 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 561 667 8.3E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS30190 62e6ebe872ec813e07e4e4131990ffdb 1302 Gene3D G3DSA:3.30.565.10 479 668 1.9E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS10000 39cfe7cea1e8189762bc03fc1e924ea6 254 SUPERFAMILY SSF52540 4 233 6.31E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10000 39cfe7cea1e8189762bc03fc1e924ea6 254 SMART SM00382 32 226 1.3E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS10000 39cfe7cea1e8189762bc03fc1e924ea6 254 Pfam PF00005 ABC transporter 23 174 1.8E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS10000 39cfe7cea1e8189762bc03fc1e924ea6 254 Gene3D G3DSA:3.40.50.300 1 253 2.3E-40 T 28-03-2018 SMD44_RS10000 39cfe7cea1e8189762bc03fc1e924ea6 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 1.5E-104 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 SMD44_RS21405 d396f43b79fe0fa6585b6320bbb2ed88 298 SUPERFAMILY SSF57845 14 46 2.22E-5 T 28-03-2018 SMD44_RS21405 d396f43b79fe0fa6585b6320bbb2ed88 298 Gene3D G3DSA:1.20.1540.10 84 266 2.2E-42 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD44_RS21405 d396f43b79fe0fa6585b6320bbb2ed88 298 Pfam PF01694 Rhomboid family 131 265 5.0E-36 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD44_RS21405 d396f43b79fe0fa6585b6320bbb2ed88 298 SUPERFAMILY SSF144091 84 270 4.97E-44 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 Gene3D G3DSA:3.40.640.10 65 320 2.5E-68 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 Gene3D G3DSA:3.90.1150.10 321 417 6.6E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 Pfam PF00155 Aminotransferase class I and II 51 414 1.2E-67 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 SUPERFAMILY SSF53383 25 416 1.16E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 219 242 2.7E-11 T 28-03-2018 SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 135 156 2.7E-11 T 28-03-2018 SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 183 207 2.7E-11 T 28-03-2018 SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 252 276 2.7E-11 T 28-03-2018 SMD44_RS22570 2a2833e91e2babfe4acb6c2f8b05ff40 417 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 113 133 2.7E-11 T 28-03-2018 SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 SMART SM00922 142 232 1.1E-13 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 19 124 3.2E-6 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 Gene3D G3DSA:3.30.390.10 1 131 6.3E-19 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 Gene3D G3DSA:3.40.630.30 342 499 7.5E-14 T 28-03-2018 SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 182 213 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 SUPERFAMILY SSF55729 383 482 1.98E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 Gene3D G3DSA:3.20.20.120 132 341 2.2E-46 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 SUPERFAMILY SSF54826 2 124 2.02E-17 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 Pfam PF00583 Acetyltransferase (GNAT) family 385 475 1.4E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 Pfam PF13378 Enolase C-terminal domain-like 149 344 1.1E-35 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS00300 803beaa283347b3dcea4769cf226d4d1 500 SUPERFAMILY SSF51604 130 340 4.59E-45 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS22505 e30250ab887d13d8c8d82ae822472da6 419 SUPERFAMILY SSF46894 342 416 4.08E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS22505 e30250ab887d13d8c8d82ae822472da6 419 SMART SM00421 352 409 3.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22505 e30250ab887d13d8c8d82ae822472da6 419 Pfam PF00196 Bacterial regulatory proteins, luxR family 359 405 1.1E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22505 e30250ab887d13d8c8d82ae822472da6 419 Gene3D G3DSA:1.10.10.10 84 419 1.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 184 376 1.2E-41 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 55 70 2.3E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 98 118 2.3E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 25 50 2.3E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 183 205 2.3E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 76 96 2.3E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 Gene3D G3DSA:2.102.10.10 32 142 6.6E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 Pfam PF00355 Rieske [2Fe-2S] domain 41 125 3.8E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 SUPERFAMILY SSF55961 176 373 1.49E-42 T 28-03-2018 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 SUPERFAMILY SSF50022 16 154 1.01E-42 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS06785 9710abc4402cba7025f15c91063c7b54 377 Gene3D G3DSA:3.90.380.10 143 377 1.8E-56 T 28-03-2018 SMD44_RS43575 cd59ed8847770792590c6d11e1bd33f7 392 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 6 337 1.2E-89 T 28-03-2018 IPR010148 CRISPR-associated protein, CT1975 SMD44_RS43575 cd59ed8847770792590c6d11e1bd33f7 392 Pfam PF09344 CT1975-like protein 8 375 1.8E-107 T 28-03-2018 IPR010148 CRISPR-associated protein, CT1975 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 Gene3D G3DSA:1.25.40.10 574 687 4.2E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 SUPERFAMILY SSF46894 889 946 1.9E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 SMART SM00421 893 950 8.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 896 910 1.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 926 938 1.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 910 926 1.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 Gene3D G3DSA:1.25.40.10 397 541 0.0093 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 Gene3D G3DSA:1.25.40.10 688 871 1.6E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 Gene3D G3DSA:1.10.10.10 892 951 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 Pfam PF00196 Bacterial regulatory proteins, luxR family 895 946 1.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 SUPERFAMILY SSF48452 592 699 8.54E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 ProSitePatterns PS00622 LuxR-type HTH domain signature. 910 937 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 Pfam PF13191 AAA ATPase domain 3 189 1.3E-14 T 28-03-2018 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 Gene3D G3DSA:3.40.50.300 5 251 2.9E-5 T 28-03-2018 SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 SUPERFAMILY SSF52540 129 249 1.94E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS36750 d02347f98f602612646a3f55f0ce588e 956 SUPERFAMILY SSF52540 10 64 1.94E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34995 2d560ab9968b0f75881af1cf54b323b7 456 Gene3D G3DSA:3.40.50.2000 72 181 2.6E-4 T 28-03-2018 SMD44_RS34995 2d560ab9968b0f75881af1cf54b323b7 456 SUPERFAMILY SSF53756 34 168 1.32E-6 T 28-03-2018 SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 Gene3D G3DSA:1.10.1660.10 1 56 5.1E-22 T 28-03-2018 SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 SMART SM00422 1 70 1.8E-33 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 Pfam PF13411 MerR HTH family regulatory protein 1 69 9.9E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.1E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.1E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.1E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 SUPERFAMILY SSF46955 1 116 4.76E-28 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS00560 013a76d340ce0ebd1ac5ceb95738d0dd 132 Gene3D G3DSA:1.10.1660.10 57 132 3.3E-16 T 28-03-2018 SMD44_RS19590 2a78d24629e35f9392fc976ea004dd22 401 Gene3D G3DSA:3.30.9.10 108 164 3.0E-9 T 28-03-2018 SMD44_RS19590 2a78d24629e35f9392fc976ea004dd22 401 Pfam PF01266 FAD dependent oxidoreductase 11 396 1.1E-60 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS19590 2a78d24629e35f9392fc976ea004dd22 401 Gene3D G3DSA:3.40.50.20 10 107 2.2E-4 T 28-03-2018 SMD44_RS19590 2a78d24629e35f9392fc976ea004dd22 401 SUPERFAMILY SSF51905 9 291 1.34E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19590 2a78d24629e35f9392fc976ea004dd22 401 Gene3D G3DSA:3.30.9.10 165 352 7.9E-31 T 28-03-2018 SMD44_RS07305 89a6d789ebdfd705247f15dc28a65a56 162 SMART SM00894 125 161 2.3E-18 T 28-03-2018 IPR008613 Excalibur calcium-binding domain SMD44_RS07305 89a6d789ebdfd705247f15dc28a65a56 162 Pfam PF05901 Excalibur calcium-binding domain 126 160 5.7E-13 T 28-03-2018 IPR008613 Excalibur calcium-binding domain SMD44_RS10750 30336860be9072adfce538a71673f261 285 PIRSF PIRSF015582 5 284 1.6E-70 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like SMD44_RS10750 30336860be9072adfce538a71673f261 285 SUPERFAMILY SSF51621 7 236 4.89E-54 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS10750 30336860be9072adfce538a71673f261 285 Gene3D G3DSA:3.20.20.360 3 263 2.3E-53 T 28-03-2018 SMD44_RS10750 30336860be9072adfce538a71673f261 285 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 8 224 8.8E-37 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMD44_RS42030 b1716d6f3bc6f7cd6297d8b6236078d6 160 SUPERFAMILY SSF52540 74 142 9.46E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS42030 b1716d6f3bc6f7cd6297d8b6236078d6 160 Gene3D G3DSA:3.40.50.300 66 142 4.3E-4 T 28-03-2018 SMD44_RS07410 932e5d70bf315563125ebc036dc35fbb 275 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 109 271 1.5E-23 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS07410 932e5d70bf315563125ebc036dc35fbb 275 Gene3D G3DSA:2.40.100.10 89 275 1.9E-36 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS07410 932e5d70bf315563125ebc036dc35fbb 275 SUPERFAMILY SSF50891 109 272 4.68E-29 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 Pfam PF04539 Sigma-70 region 3 187 263 6.6E-25 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 SUPERFAMILY SSF88946 32 178 6.28E-47 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 132 145 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 Gene3D G3DSA:1.10.10.10 270 336 1.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 301 327 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 SUPERFAMILY SSF88659 181 254 1.44E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 Gene3D G3DSA:1.10.601.10 5 177 2.9E-58 T 28-03-2018 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 Pfam PF04542 Sigma-70 region 2 108 178 1.5E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 104 329 6.5E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 Gene3D G3DSA:1.10.10.10 178 228 1.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 SUPERFAMILY SSF88659 239 334 2.76E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 PRINTS PR00046 Major sigma-70 factor signature 316 327 5.3E-25 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 PRINTS PR00046 Major sigma-70 factor signature 156 164 5.3E-25 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 PRINTS PR00046 Major sigma-70 factor signature 301 316 5.3E-25 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 PRINTS PR00046 Major sigma-70 factor signature 132 145 5.3E-25 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 PRINTS PR00046 Major sigma-70 factor signature 280 292 5.3E-25 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 Pfam PF04545 Sigma-70, region 4 277 329 3.3E-14 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS17420 5fe619160d4b84f523a38f2efb8d1b9e 340 Pfam PF00140 Sigma-70 factor, region 1.2 34 67 1.6E-10 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS02785 1c4373eb75bca59d8ca0430154aaa737 483 Pfam PF00561 alpha/beta hydrolase fold 106 339 1.5E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS02785 1c4373eb75bca59d8ca0430154aaa737 483 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 177 207 - T 28-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 SMD44_RS02785 1c4373eb75bca59d8ca0430154aaa737 483 Gene3D G3DSA:3.40.50.1820 78 481 1.3E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02785 1c4373eb75bca59d8ca0430154aaa737 483 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 198 212 3.5E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS02785 1c4373eb75bca59d8ca0430154aaa737 483 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 116 3.5E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS02785 1c4373eb75bca59d8ca0430154aaa737 483 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 139 150 3.5E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS02785 1c4373eb75bca59d8ca0430154aaa737 483 SUPERFAMILY SSF53474 331 463 1.2E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02785 1c4373eb75bca59d8ca0430154aaa737 483 SUPERFAMILY SSF53474 98 228 1.2E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28505 b541c15939e5de1effa9a882ea83af18 209 SUPERFAMILY SSF160904 8 182 3.92E-39 T 28-03-2018 SMD44_RS28505 b541c15939e5de1effa9a882ea83af18 209 Pfam PF11706 CGNR zinc finger 141 183 4.8E-15 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS28505 b541c15939e5de1effa9a882ea83af18 209 Pfam PF07336 Putative stress-induced transcription regulator 9 135 3.8E-16 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS28505 b541c15939e5de1effa9a882ea83af18 209 Gene3D G3DSA:1.10.3300.10 4 185 6.8E-42 T 28-03-2018 IPR023286 ABATE domain SMD44_RS00395 217de9474c02236630f41f1c454f750f 111 SUPERFAMILY SSF48576 9 91 4.68E-10 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS00395 217de9474c02236630f41f1c454f750f 111 Gene3D G3DSA:1.10.600.10 6 90 2.8E-13 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS08615 b3969063b2a49f50e1d9cd97d0370d47 498 TIGRFAM TIGR00784 citMHS: citrate transporter 1 214 6.8E-83 T 28-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 SMD44_RS08615 b3969063b2a49f50e1d9cd97d0370d47 498 Pfam PF03600 Citrate transporter 13 446 2.5E-51 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 Gene3D G3DSA:3.30.479.20 57 150 1.6E-23 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 Gene3D G3DSA:1.10.286.20 209 229 7.3E-18 T 28-03-2018 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 SUPERFAMILY SSF54713 57 147 4.97E-19 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 Hamap MF_00050 Elongation factor Ts [tsf]. 1 278 64.234 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 SUPERFAMILY SSF46934 3 55 8.93E-16 T 28-03-2018 IPR009060 UBA-like GO:0005515 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 SUPERFAMILY SSF54713 150 277 9.81E-38 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 Gene3D G3DSA:1.10.8.10 1 56 1.6E-20 T 28-03-2018 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 277 3.3E-74 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 Pfam PF00889 Elongation factor TS 73 277 2.3E-61 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 Gene3D G3DSA:3.30.479.20 151 208 1.1E-8 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS30570 ecf0d3a8d966be6841d420c0aacd2a7e 278 Gene3D G3DSA:3.30.479.20 230 277 1.5E-11 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD44_RS36060 c39e2599a99f45f7f507ec9692aae3f7 156 SUPERFAMILY SSF54427 17 131 4.07E-14 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS36060 c39e2599a99f45f7f507ec9692aae3f7 156 Pfam PF12680 SnoaL-like domain 25 126 9.7E-9 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS36060 c39e2599a99f45f7f507ec9692aae3f7 156 Gene3D G3DSA:3.10.450.50 10 156 1.0E-17 T 28-03-2018 SMD44_RS00425 8b126166bf177d9cb9efbdb94107c697 200 Gene3D G3DSA:2.60.120.10 8 115 2.2E-37 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS00425 8b126166bf177d9cb9efbdb94107c697 200 Gene3D G3DSA:2.60.120.10 116 197 3.3E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS00425 8b126166bf177d9cb9efbdb94107c697 200 SUPERFAMILY SSF51182 2 196 2.67E-46 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS00425 8b126166bf177d9cb9efbdb94107c697 200 Pfam PF05962 HutD 8 192 3.7E-57 T 28-03-2018 IPR010282 Uncharacterised protein family HutD/Ves SMD44_RS30915 3525ef736541205aefe8bc7923da8df7 320 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 41 75 1.5E-7 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS30915 3525ef736541205aefe8bc7923da8df7 320 SUPERFAMILY SSF161098 110 300 8.24E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30915 3525ef736541205aefe8bc7923da8df7 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 316 7.0E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30915 3525ef736541205aefe8bc7923da8df7 320 Gene3D G3DSA:1.10.3720.10 39 305 7.4E-42 T 28-03-2018 SMD44_RS27170 123b0bb234c72748b5561cf41037a840 432 Gene3D G3DSA:3.40.50.1460 196 415 6.4E-8 T 28-03-2018 SMD44_RS27170 123b0bb234c72748b5561cf41037a840 432 Pfam PF12770 CHAT domain 264 395 6.2E-6 T 28-03-2018 IPR024983 CHAT domain SMD44_RS41370 c38695d9212b9d5063c1fdd8d12091e2 197 Gene3D G3DSA:2.60.40.10 120 183 0.0014 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS41370 c38695d9212b9d5063c1fdd8d12091e2 197 Gene3D G3DSA:2.60.40.10 29 111 3.1E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 Gene3D G3DSA:3.40.50.261 233 389 1.1E-35 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 Pfam PF00549 CoA-ligase 257 376 1.0E-13 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 PIRSF PIRSF001554 1 392 9.7E-136 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 389 6.5E-123 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 390 37.222 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 250 274 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 Pfam PF08442 ATP-grasp domain 2 195 5.3E-67 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 Gene3D G3DSA:3.30.1490.20 21 86 1.0E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 SUPERFAMILY SSF52210 232 389 2.09E-42 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 Gene3D G3DSA:3.30.470.20 87 232 1.6E-47 T 28-03-2018 SMD44_RS26010 79b2f4d83ee77e818189dff87cd1c4d5 393 SUPERFAMILY SSF56059 3 228 6.33E-64 T 28-03-2018 SMD44_RS26305 a82aed6103ddad17accdc02e5628af33 278 SMART SM00530 24 79 7.0E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS26305 a82aed6103ddad17accdc02e5628af33 278 Pfam PF13560 Helix-turn-helix domain 21 77 3.5E-10 T 28-03-2018 SMD44_RS26305 a82aed6103ddad17accdc02e5628af33 278 SUPERFAMILY SSF47413 19 73 5.33E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS26305 a82aed6103ddad17accdc02e5628af33 278 Gene3D G3DSA:1.10.3100.10 15 153 1.1E-11 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS36290 0dca7361bc685833e23be3265dd60c5d 490 Gene3D G3DSA:3.90.1150.10 354 472 6.8E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS36290 0dca7361bc685833e23be3265dd60c5d 490 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 78 472 4.1E-154 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMD44_RS36290 0dca7361bc685833e23be3265dd60c5d 490 SUPERFAMILY SSF53383 76 472 8.34E-118 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS36290 0dca7361bc685833e23be3265dd60c5d 490 Pfam PF00266 Aminotransferase class-V 96 465 3.0E-135 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS36290 0dca7361bc685833e23be3265dd60c5d 490 Gene3D G3DSA:3.40.640.10 105 353 4.0E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS16795 653208faf480bf080113ebd638723516 239 SUPERFAMILY SSF81995 121 180 3.14E-5 T 28-03-2018 SMD44_RS16795 653208faf480bf080113ebd638723516 239 Gene3D G3DSA:1.10.530.10 10 123 1.2E-30 T 28-03-2018 SMD44_RS16795 653208faf480bf080113ebd638723516 239 SUPERFAMILY SSF53955 45 119 5.72E-31 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS16795 653208faf480bf080113ebd638723516 239 SMART SM00257 191 239 2.9E-8 T 28-03-2018 IPR018392 LysM domain SMD44_RS16795 653208faf480bf080113ebd638723516 239 Gene3D G3DSA:3.10.350.10 185 239 1.7E-13 T 28-03-2018 SMD44_RS16795 653208faf480bf080113ebd638723516 239 SUPERFAMILY SSF54106 191 238 4.45E-6 T 28-03-2018 IPR018392 LysM domain SMD44_RS16795 653208faf480bf080113ebd638723516 239 Pfam PF01476 LysM domain 192 238 5.6E-10 T 28-03-2018 IPR018392 LysM domain SMD44_RS16795 653208faf480bf080113ebd638723516 239 Pfam PF06737 Transglycosylase-like domain 42 117 5.7E-35 T 28-03-2018 IPR010618 Transglycosylase-like SMD44_RS03770 16c25b4a6733fc25845f361aefa73cb1 244 Gene3D G3DSA:3.40.140.10 4 131 8.7E-22 T 28-03-2018 SMD44_RS03770 16c25b4a6733fc25845f361aefa73cb1 244 Gene3D G3DSA:2.30.130.30 135 238 1.1E-16 T 28-03-2018 SMD44_RS03770 16c25b4a6733fc25845f361aefa73cb1 244 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 98 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMD44_RS03770 16c25b4a6733fc25845f361aefa73cb1 244 SUPERFAMILY SSF53927 13 128 6.22E-22 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMD44_RS03770 16c25b4a6733fc25845f361aefa73cb1 244 SUPERFAMILY SSF88697 138 236 4.47E-14 T 28-03-2018 IPR015947 PUA-like domain SMD44_RS03770 16c25b4a6733fc25845f361aefa73cb1 244 SMART SM01022 139 239 5.7E-8 T 28-03-2018 IPR007374 ASCH domain SMD44_RS03770 16c25b4a6733fc25845f361aefa73cb1 244 Pfam PF04266 ASCH domain 141 237 7.4E-9 T 28-03-2018 IPR007374 ASCH domain SMD44_RS39170 56f3813920201bf1803a09b304e42c48 247 SUPERFAMILY SSF56784 19 244 7.04E-41 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS39170 56f3813920201bf1803a09b304e42c48 247 Gene3D G3DSA:3.40.50.1000 101 245 7.8E-25 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS39170 56f3813920201bf1803a09b304e42c48 247 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 18 212 1.4E-45 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase SMD44_RS39170 56f3813920201bf1803a09b304e42c48 247 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 99 211 1.7E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS39170 56f3813920201bf1803a09b304e42c48 247 Pfam PF00702 haloacid dehalogenase-like hydrolase 19 207 3.3E-15 T 28-03-2018 SMD44_RS39170 56f3813920201bf1803a09b304e42c48 247 Gene3D G3DSA:1.10.150.240 30 100 6.0E-24 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 Gene3D G3DSA:1.20.120.530 85 225 9.0E-35 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 Pfam PF07729 FCD domain 92 213 2.9E-26 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 4.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 4.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 SUPERFAMILY SSF48008 88 220 1.94E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 3.3E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 SUPERFAMILY SSF46785 14 108 8.39E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 SMART SM00895 92 214 1.1E-20 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 Gene3D G3DSA:1.10.10.10 8 84 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34700 178d66203d0ffb73d630dd8e1110db9a 225 SMART SM00345 24 82 7.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS09850 ae413f2e094f3af68a15494896678eaf 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 305 8.0E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS09850 ae413f2e094f3af68a15494896678eaf 316 SUPERFAMILY SSF161098 73 298 3.4E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS09850 ae413f2e094f3af68a15494896678eaf 316 Gene3D G3DSA:1.10.3720.10 79 309 3.9E-44 T 28-03-2018 SMD44_RS09850 ae413f2e094f3af68a15494896678eaf 316 Gene3D G3DSA:1.20.58.370 23 61 5.0E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMD44_RS27675 aef9d067d85f05c25626c6f5b1a214f3 774 Gene3D G3DSA:3.40.190.10 181 371 2.7E-37 T 28-03-2018 SMD44_RS27675 aef9d067d85f05c25626c6f5b1a214f3 774 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 346 447 1.0E-13 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS27675 aef9d067d85f05c25626c6f5b1a214f3 774 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 113 285 1.5E-21 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS27675 aef9d067d85f05c25626c6f5b1a214f3 774 Gene3D G3DSA:3.90.76.10 87 180 7.9E-13 T 28-03-2018 SMD44_RS27675 aef9d067d85f05c25626c6f5b1a214f3 774 SUPERFAMILY SSF53850 51 283 1.99E-39 T 28-03-2018 SMD44_RS27675 aef9d067d85f05c25626c6f5b1a214f3 774 SUPERFAMILY SSF53850 346 448 1.99E-39 T 28-03-2018 SMD44_RS27675 aef9d067d85f05c25626c6f5b1a214f3 774 Gene3D G3DSA:3.10.105.10 372 731 5.4E-80 T 28-03-2018 SMD44_RS27675 aef9d067d85f05c25626c6f5b1a214f3 774 SUPERFAMILY SSF53850 588 760 2.02E-21 T 28-03-2018 SMD44_RS26630 be32a21a2043269011540ba0cf369e15 223 SUPERFAMILY SSF88946 5 105 1.57E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26630 be32a21a2043269011540ba0cf369e15 223 Pfam PF08281 Sigma-70, region 4 126 177 1.7E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26630 be32a21a2043269011540ba0cf369e15 223 SUPERFAMILY SSF88659 126 181 6.92E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26630 be32a21a2043269011540ba0cf369e15 223 Pfam PF04542 Sigma-70 region 2 28 94 2.3E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26630 be32a21a2043269011540ba0cf369e15 223 Gene3D G3DSA:1.10.10.10 126 186 1.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26630 be32a21a2043269011540ba0cf369e15 223 Gene3D G3DSA:1.10.1740.10 1 125 1.5E-24 T 28-03-2018 SMD44_RS26630 be32a21a2043269011540ba0cf369e15 223 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 180 6.2E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS02635 695022c117541ad62978f5d32e3cd793 339 Pfam PF00005 ABC transporter 18 156 4.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS02635 695022c117541ad62978f5d32e3cd793 339 Gene3D G3DSA:3.40.50.300 1 249 2.2E-57 T 28-03-2018 SMD44_RS02635 695022c117541ad62978f5d32e3cd793 339 SMART SM00382 26 204 2.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS02635 695022c117541ad62978f5d32e3cd793 339 SUPERFAMILY SSF52540 2 219 1.13E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 Pfam PF00128 Alpha amylase, catalytic domain 99 346 6.7E-17 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 SMART SM00642 46 383 2.2E-77 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 SUPERFAMILY SSF51445 46 385 3.74E-84 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 Gene3D G3DSA:3.20.20.80 43 388 4.1E-73 T 28-03-2018 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 Gene3D G3DSA:2.60.40.1180 390 468 3.1E-29 T 28-03-2018 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 SMART SM00632 392 468 1.2E-38 T 28-03-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 SUPERFAMILY SSF51011 388 469 2.69E-27 T 28-03-2018 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 PRINTS PR00110 Alpha-amylase signature 239 257 9.3E-24 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 PRINTS PR00110 Alpha-amylase signature 297 309 9.3E-24 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 PRINTS PR00110 Alpha-amylase signature 121 132 9.3E-24 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 PRINTS PR00110 Alpha-amylase signature 210 221 9.3E-24 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 PRINTS PR00110 Alpha-amylase signature 89 106 9.3E-24 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD44_RS05280 a2de48ba710cb7e7d81a660dee700e58 472 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 395 451 9.3E-11 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 SMD44_RS12175 2ab0e78cfd1023fee4be6ca27c0142dc 180 SMART SM00903 22 168 4.5E-44 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS12175 2ab0e78cfd1023fee4be6ca27c0142dc 180 Pfam PF01613 Flavin reductase like domain 22 169 5.1E-30 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS12175 2ab0e78cfd1023fee4be6ca27c0142dc 180 SUPERFAMILY SSF50475 18 170 3.44E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS12175 2ab0e78cfd1023fee4be6ca27c0142dc 180 Gene3D G3DSA:2.30.110.10 4 169 1.7E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS29360 c3d8fcb88425541fd6aa8506b9e03cf5 185 Gene3D G3DSA:1.10.10.60 41 129 4.3E-11 T 28-03-2018 SMD44_RS29360 c3d8fcb88425541fd6aa8506b9e03cf5 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29360 c3d8fcb88425541fd6aa8506b9e03cf5 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29360 c3d8fcb88425541fd6aa8506b9e03cf5 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 49 1.0E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29360 c3d8fcb88425541fd6aa8506b9e03cf5 185 Gene3D G3DSA:1.10.10.60 1 40 1.5E-15 T 28-03-2018 SMD44_RS29360 c3d8fcb88425541fd6aa8506b9e03cf5 185 SUPERFAMILY SSF46689 2 63 1.74E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29360 c3d8fcb88425541fd6aa8506b9e03cf5 185 SUPERFAMILY SSF48498 102 173 2.35E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS09935 93072cf749295b7f4ca3276c3fd860c1 265 Gene3D G3DSA:3.40.50.1110 6 194 3.2E-32 T 28-03-2018 SMD44_RS09935 93072cf749295b7f4ca3276c3fd860c1 265 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 11 184 4.0E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS09935 93072cf749295b7f4ca3276c3fd860c1 265 SUPERFAMILY SSF52266 6 193 2.66E-36 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS26640 7700a664c8113b0e79c1d96a9edd5bd4 312 Pfam PF01471 Putative peptidoglycan binding domain 114 168 1.3E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS26640 7700a664c8113b0e79c1d96a9edd5bd4 312 Pfam PF03734 L,D-transpeptidase catalytic domain 200 310 8.2E-14 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD44_RS26640 7700a664c8113b0e79c1d96a9edd5bd4 312 SUPERFAMILY SSF141523 198 311 4.19E-22 T 28-03-2018 SMD44_RS26640 7700a664c8113b0e79c1d96a9edd5bd4 312 Gene3D G3DSA:1.10.101.10 103 179 3.3E-15 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS26640 7700a664c8113b0e79c1d96a9edd5bd4 312 Gene3D G3DSA:2.40.440.10 193 312 5.9E-24 T 28-03-2018 SMD44_RS26640 7700a664c8113b0e79c1d96a9edd5bd4 312 SUPERFAMILY SSF47090 99 174 5.81E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 Gene3D G3DSA:2.40.30.10 343 442 1.1E-18 T 28-03-2018 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 SUPERFAMILY SSF52343 449 565 3.54E-25 T 28-03-2018 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 Gene3D G3DSA:1.10.490.10 208 342 6.5E-31 T 28-03-2018 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 Gene3D G3DSA:3.40.50.80 443 570 3.1E-18 T 28-03-2018 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 SUPERFAMILY SSF63380 348 443 1.2E-22 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 Pfam PF00970 Oxidoreductase FAD-binding domain 352 443 1.4E-10 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 Pfam PF00175 Oxidoreductase NAD-binding domain 456 546 1.4E-10 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 394 401 9.4E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 479 488 9.4E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 454 473 9.4E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 Pfam PF00042 Globin 211 303 7.2E-10 T 28-03-2018 IPR000971 Globin GO:0020037 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 SUPERFAMILY SSF46458 210 337 1.56E-31 T 28-03-2018 IPR009050 Globin-like SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 PRINTS PR00410 Phenol hydroxylase reductase family signature 479 488 2.1E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 PRINTS PR00410 Phenol hydroxylase reductase family signature 376 388 2.1E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD44_RS20905 e12cc6d9e50e977b5dcaf210cd5d018d 575 PRINTS PR00410 Phenol hydroxylase reductase family signature 454 473 2.1E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD44_RS04130 927446a92e1f2db68dc976868fdbc429 429 SMART SM00387 331 423 4.6E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04130 927446a92e1f2db68dc976868fdbc429 429 SUPERFAMILY SSF55874 305 420 5.42E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04130 927446a92e1f2db68dc976868fdbc429 429 Pfam PF07730 Histidine kinase 224 289 7.6E-20 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS04130 927446a92e1f2db68dc976868fdbc429 429 Gene3D G3DSA:3.30.565.10 300 423 9.9E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05390 c1349fe46688b4c74a1701404b4323fe 201 SUPERFAMILY SSF48498 99 200 5.04E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS05390 c1349fe46688b4c74a1701404b4323fe 201 Gene3D G3DSA:1.10.357.10 13 201 5.2E-35 T 28-03-2018 SMD44_RS05390 c1349fe46688b4c74a1701404b4323fe 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 1.1E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05390 c1349fe46688b4c74a1701404b4323fe 201 SUPERFAMILY SSF46689 21 100 3.29E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05390 c1349fe46688b4c74a1701404b4323fe 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 1.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05390 c1349fe46688b4c74a1701404b4323fe 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 1.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS09750 332adb5e7139d252989d8164b6411a01 513 SUPERFAMILY SSF53720 8 505 2.23E-81 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS09750 332adb5e7139d252989d8164b6411a01 513 Gene3D G3DSA:3.40.605.10 2 256 1.6E-46 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS09750 332adb5e7139d252989d8164b6411a01 513 Gene3D G3DSA:3.40.309.10 257 452 6.3E-24 T 28-03-2018 SMD44_RS09750 332adb5e7139d252989d8164b6411a01 513 Pfam PF00171 Aldehyde dehydrogenase family 8 408 7.3E-43 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS35355 a6fb4a3defe3b3fc460becf16e7339d3 267 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 35 46 1.1E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS35355 a6fb4a3defe3b3fc460becf16e7339d3 267 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 70 90 1.1E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS35355 a6fb4a3defe3b3fc460becf16e7339d3 267 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 59 1.1E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS35355 a6fb4a3defe3b3fc460becf16e7339d3 267 Pfam PF13411 MerR HTH family regulatory protein 34 102 1.2E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS35355 a6fb4a3defe3b3fc460becf16e7339d3 267 SUPERFAMILY SSF46955 34 115 2.34E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS35355 a6fb4a3defe3b3fc460becf16e7339d3 267 SMART SM00422 34 103 5.2E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS35355 a6fb4a3defe3b3fc460becf16e7339d3 267 Gene3D G3DSA:1.10.1660.10 23 265 3.5E-22 T 28-03-2018 SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 PIRSF PIRSF001587 7 749 8.0E-289 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 SUPERFAMILY SSF55326 409 578 5.5E-56 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Gene3D G3DSA:3.90.650.10 190 381 7.3E-37 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Gene3D G3DSA:3.30.1330.10 23 189 2.3E-54 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Gene3D G3DSA:3.30.1330.10 406 577 2.2E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Gene3D G3DSA:3.90.650.10 581 749 3.9E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 749 309.67 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 212 366 5.7E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 585 722 4.6E-20 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 SUPERFAMILY SSF56042 209 439 6.73E-52 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 SUPERFAMILY SSF55326 20 204 8.22E-50 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 24 744 2.2E-261 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 454 572 2.4E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 96 198 1.8E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS19975 41d8b76f7b39abd20b630989716b7036 749 SUPERFAMILY SSF56042 583 748 2.24E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS42065 fd7a82944c4955972baeb6b2cf5ab4e8 302 Pfam PF12146 Serine aminopeptidase, S33 147 254 2.3E-17 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SMD44_RS42065 fd7a82944c4955972baeb6b2cf5ab4e8 302 Gene3D G3DSA:3.40.50.1820 111 297 1.6E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS42065 fd7a82944c4955972baeb6b2cf5ab4e8 302 SUPERFAMILY SSF53474 122 276 1.2E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05295 09a5ffc5173c24ffabaa809f7c6a1c78 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 275 2.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS05295 09a5ffc5173c24ffabaa809f7c6a1c78 282 Gene3D G3DSA:1.10.3720.10 16 271 1.4E-43 T 28-03-2018 SMD44_RS05295 09a5ffc5173c24ffabaa809f7c6a1c78 282 SUPERFAMILY SSF161098 12 281 4.3E-69 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS25480 ee64cb09aaad64a9c40834cb18126495 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.671 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SMD44_RS25480 ee64cb09aaad64a9c40834cb18126495 156 SUPERFAMILY SSF47973 1 149 3.66E-57 T 28-03-2018 IPR023798 Ribosomal protein S7 domain SMD44_RS25480 ee64cb09aaad64a9c40834cb18126495 156 Gene3D G3DSA:1.10.455.10 6 156 1.3E-54 T 28-03-2018 IPR023798 Ribosomal protein S7 domain SMD44_RS25480 ee64cb09aaad64a9c40834cb18126495 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.0E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain SMD44_RS25480 ee64cb09aaad64a9c40834cb18126495 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.2E-64 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SMD44_RS25480 ee64cb09aaad64a9c40834cb18126495 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25480 ee64cb09aaad64a9c40834cb18126495 156 PIRSF PIRSF002122 7 156 1.8E-55 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 SMD44_RS34855 397323d457a00276b73beb7d3ebea971 87 Gene3D G3DSA:1.10.260.40 5 76 4.2E-14 T 28-03-2018 SMD44_RS34855 397323d457a00276b73beb7d3ebea971 87 Pfam PF01381 Helix-turn-helix 10 54 1.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS34855 397323d457a00276b73beb7d3ebea971 87 SMART SM00530 6 60 5.9E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS34855 397323d457a00276b73beb7d3ebea971 87 SUPERFAMILY SSF47413 8 67 2.01E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 Pfam PF13516 Leucine Rich repeat 204 217 0.45 T 28-03-2018 IPR001611 Leucine-rich repeat GO:0005515 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 Gene3D G3DSA:3.80.10.10 184 228 8.6E-10 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 Gene3D G3DSA:3.80.10.10 138 183 6.7E-14 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00369 157 179 15.0 T 28-03-2018 IPR003591 Leucine-rich repeat, typical subtype SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00369 134 156 0.1 T 28-03-2018 IPR003591 Leucine-rich repeat, typical subtype SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00369 64 87 6.0 T 28-03-2018 IPR003591 Leucine-rich repeat, typical subtype SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00369 88 110 26.0 T 28-03-2018 IPR003591 Leucine-rich repeat, typical subtype SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00369 180 203 1.3 T 28-03-2018 IPR003591 Leucine-rich repeat, typical subtype SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00369 41 63 0.093 T 28-03-2018 IPR003591 Leucine-rich repeat, typical subtype SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00369 111 133 17.0 T 28-03-2018 IPR003591 Leucine-rich repeat, typical subtype SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 Pfam PF13855 Leucine rich repeat 135 193 7.4E-11 T 28-03-2018 IPR001611 Leucine-rich repeat GO:0005515 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 Pfam PF13855 Leucine rich repeat 71 124 7.3E-9 T 28-03-2018 IPR001611 Leucine-rich repeat GO:0005515 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00364 65 84 220.0 T 28-03-2018 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00364 41 61 350.0 T 28-03-2018 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00364 134 153 170.0 T 28-03-2018 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00364 88 107 0.18 T 28-03-2018 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00364 111 130 7.6 T 28-03-2018 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SMART SM00364 180 199 190.0 T 28-03-2018 SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 Gene3D G3DSA:3.80.10.10 1 137 5.6E-33 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMD44_RS03355 4bef183c264791b9cffa9aa4b7cc34d9 235 SUPERFAMILY SSF52058 14 218 2.81E-46 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMD44_RS36230 e91ecce572dd2f52f119f1996fe01608 414 SUPERFAMILY SSF53901 220 412 1.9E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36230 e91ecce572dd2f52f119f1996fe01608 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMD44_RS36230 e91ecce572dd2f52f119f1996fe01608 414 Gene3D G3DSA:3.40.47.10 4 264 9.4E-71 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36230 e91ecce572dd2f52f119f1996fe01608 414 SMART SM00825 Beta-ketoacyl synthase 13 414 8.0E-16 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36230 e91ecce572dd2f52f119f1996fe01608 414 Gene3D G3DSA:3.40.47.10 268 414 1.5E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36230 e91ecce572dd2f52f119f1996fe01608 414 SUPERFAMILY SSF53901 11 257 1.35E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36230 e91ecce572dd2f52f119f1996fe01608 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 371 2.3E-32 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36230 e91ecce572dd2f52f119f1996fe01608 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 252 4.5E-48 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS23630 6cd84a965ccde4f93b03ccb35a7efa94 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS23630 6cd84a965ccde4f93b03ccb35a7efa94 485 Pfam PF00171 Aldehyde dehydrogenase family 25 474 7.5E-155 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS23630 6cd84a965ccde4f93b03ccb35a7efa94 485 Gene3D G3DSA:3.40.605.10 5 268 1.2E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS23630 6cd84a965ccde4f93b03ccb35a7efa94 485 SUPERFAMILY SSF53720 6 480 1.7E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS23630 6cd84a965ccde4f93b03ccb35a7efa94 485 Gene3D G3DSA:3.40.309.10 269 459 8.2E-67 T 28-03-2018 SMD44_RS23630 6cd84a965ccde4f93b03ccb35a7efa94 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS18375 26bb295affd26fcf6d79056444ccc9ae 418 Pfam PF02687 FtsX-like permease family 326 412 1.7E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS18375 26bb295affd26fcf6d79056444ccc9ae 418 Pfam PF12704 MacB-like periplasmic core domain 40 232 7.4E-19 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS04745 bd7045f5197a09327a186a3e9f917b96 266 Pfam PF03374 Phage antirepressor protein KilAC domain 136 249 9.1E-17 T 28-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 SMD44_RS04745 bd7045f5197a09327a186a3e9f917b96 266 SMART SM01040 15 101 5.2E-30 T 28-03-2018 IPR003497 BRO N-terminal domain SMD44_RS04745 bd7045f5197a09327a186a3e9f917b96 266 Pfam PF02498 BRO family, N-terminal domain 15 101 1.1E-21 T 28-03-2018 IPR003497 BRO N-terminal domain SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 Gene3D G3DSA:3.40.50.300 4 66 1.7E-16 T 28-03-2018 SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 Gene3D G3DSA:3.30.300.20 201 317 5.7E-41 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 Pfam PF01926 50S ribosome-binding GTPase 21 136 1.1E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 Gene3D G3DSA:3.40.50.300 67 190 1.2E-14 T 28-03-2018 SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 TIGRFAM TIGR00436 era: GTP-binding protein Era 19 300 2.1E-66 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 SUPERFAMILY SSF54814 198 317 4.84E-35 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 Hamap MF_00367 GTPase Era [era]. 16 317 34.614 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 SUPERFAMILY SSF52540 22 229 2.15E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 148 1.2E-17 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMD44_RS13710 a1b1b85ed42dc91cbc6a3db7bec1eb10 317 Pfam PF07650 KH domain 224 306 3.8E-17 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS18770 40e9c2e1c5b81450be13022b8ea7a81d 413 Gene3D G3DSA:3.40.50.1820 60 256 2.0E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS18770 40e9c2e1c5b81450be13022b8ea7a81d 413 SUPERFAMILY SSF53474 64 241 3.24E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02200 cb8d9761c2c5b98a8272a6dcf23d89db 350 Pfam PF16864 Dimerisation domain 17 85 2.9E-10 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain SMD44_RS02200 cb8d9761c2c5b98a8272a6dcf23d89db 350 SUPERFAMILY SSF46785 14 93 8.73E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02200 cb8d9761c2c5b98a8272a6dcf23d89db 350 SUPERFAMILY SSF53335 99 338 7.52E-55 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS02200 cb8d9761c2c5b98a8272a6dcf23d89db 350 Pfam PF00891 O-methyltransferase 107 328 6.4E-53 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD44_RS02200 cb8d9761c2c5b98a8272a6dcf23d89db 350 PIRSF PIRSF005739 2 339 4.5E-58 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD44_RS02200 cb8d9761c2c5b98a8272a6dcf23d89db 350 Gene3D G3DSA:3.40.50.150 102 345 3.8E-46 T 28-03-2018 SMD44_RS02200 cb8d9761c2c5b98a8272a6dcf23d89db 350 Gene3D G3DSA:1.10.10.10 10 101 3.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23595 42ed980de979100bec91c67c77791eb5 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS23595 42ed980de979100bec91c67c77791eb5 54 Pfam PF00471 Ribosomal protein L33 9 54 2.2E-15 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23595 42ed980de979100bec91c67c77791eb5 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.25 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23595 42ed980de979100bec91c67c77791eb5 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 5.3E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS23595 42ed980de979100bec91c67c77791eb5 54 SUPERFAMILY SSF57829 4 54 1.1E-16 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMD44_RS01630 92a1d2f594f3a1aff816ce3b56bcc4e7 299 Gene3D G3DSA:3.40.190.10 88 182 1.3E-21 T 28-03-2018 SMD44_RS01630 92a1d2f594f3a1aff816ce3b56bcc4e7 299 SUPERFAMILY SSF53850 92 297 5.12E-37 T 28-03-2018 SMD44_RS01630 92a1d2f594f3a1aff816ce3b56bcc4e7 299 SUPERFAMILY SSF46785 2 111 4.16E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01630 92a1d2f594f3a1aff816ce3b56bcc4e7 299 Gene3D G3DSA:1.10.10.10 1 87 2.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01630 92a1d2f594f3a1aff816ce3b56bcc4e7 299 Pfam PF03466 LysR substrate binding domain 92 296 4.7E-40 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS01630 92a1d2f594f3a1aff816ce3b56bcc4e7 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS01630 92a1d2f594f3a1aff816ce3b56bcc4e7 299 Gene3D G3DSA:3.40.190.10 183 270 9.9E-22 T 28-03-2018 SMD44_RS17445 f05901c8f62f14605290e5c72e4e2b0b 435 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 97 361 1.4E-53 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD44_RS17445 f05901c8f62f14605290e5c72e4e2b0b 435 SUPERFAMILY SSF55486 222 297 1.58E-6 T 28-03-2018 SMD44_RS40945 b5e475b9779f9fe7ff74605d3792e0bd 241 Gene3D G3DSA:3.40.190.10 120 192 4.7E-7 T 28-03-2018 SMD44_RS40945 b5e475b9779f9fe7ff74605d3792e0bd 241 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 222 1.0E-19 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS40945 b5e475b9779f9fe7ff74605d3792e0bd 241 SUPERFAMILY SSF53850 34 225 3.91E-27 T 28-03-2018 SMD44_RS40945 b5e475b9779f9fe7ff74605d3792e0bd 241 SMART SM00062 18 234 2.2E-10 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS40945 b5e475b9779f9fe7ff74605d3792e0bd 241 Gene3D G3DSA:3.40.190.10 10 119 3.2E-11 T 28-03-2018 SMD44_RS21370 1120a47ba40bebf7bfd1c6e4c6e6b23e 231 Pfam PF01551 Peptidase family M23 122 219 4.7E-29 T 28-03-2018 IPR016047 Peptidase M23 SMD44_RS21370 1120a47ba40bebf7bfd1c6e4c6e6b23e 231 Gene3D G3DSA:2.70.70.10 43 226 2.3E-41 T 28-03-2018 SMD44_RS21370 1120a47ba40bebf7bfd1c6e4c6e6b23e 231 SUPERFAMILY SSF51261 87 223 7.85E-44 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS33290 ecdbacfd063c82f585bd7db17f388089 538 Pfam PF00501 AMP-binding enzyme 29 442 5.1E-115 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS33290 ecdbacfd063c82f585bd7db17f388089 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS33290 ecdbacfd063c82f585bd7db17f388089 538 Gene3D G3DSA:3.30.300.30 436 537 6.2E-29 T 28-03-2018 SMD44_RS33290 ecdbacfd063c82f585bd7db17f388089 538 Gene3D G3DSA:3.40.50.980 21 195 3.7E-41 T 28-03-2018 SMD44_RS33290 ecdbacfd063c82f585bd7db17f388089 538 Gene3D G3DSA:2.30.38.10 351 435 1.9E-29 T 28-03-2018 SMD44_RS33290 ecdbacfd063c82f585bd7db17f388089 538 Gene3D G3DSA:3.40.50.980 196 350 7.1E-54 T 28-03-2018 SMD44_RS33290 ecdbacfd063c82f585bd7db17f388089 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 527 7.0E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS33290 ecdbacfd063c82f585bd7db17f388089 538 SUPERFAMILY SSF56801 21 537 9.29E-163 T 28-03-2018 SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 Gene3D G3DSA:1.10.1740.10 1 130 2.4E-23 T 28-03-2018 SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 SUPERFAMILY SSF88946 4 98 1.57E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 Gene3D G3DSA:3.40.33.10 511 632 1.4E-17 T 28-03-2018 IPR014044 CAP domain SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 48 79 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 SUPERFAMILY SSF55797 519 631 9.24E-22 T 28-03-2018 IPR014044 CAP domain SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 Gene3D G3DSA:1.10.10.10 131 420 1.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 Pfam PF04542 Sigma-70 region 2 26 92 1.0E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 Pfam PF00188 Cysteine-rich secretory protein family 523 632 3.2E-22 T 28-03-2018 IPR014044 CAP domain SMD44_RS01580 660b6d5c97173bbd6c139a3bc1439efb 636 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 185 1.7E-18 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 Gene3D G3DSA:3.30.450.40 154 322 3.2E-22 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 SMART SM00331 343 630 2.3E-28 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 Pfam PF13185 GAF domain 202 315 1.6E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 372 534 4.1E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 Gene3D G3DSA:3.30.565.10 639 773 2.3E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 SUPERFAMILY SSF55781 177 327 3.27E-14 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 SUPERFAMILY SSF81606 359 525 9.15E-5 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 SUPERFAMILY SSF55785 30 140 9.77E-6 T 28-03-2018 IPR000014 PAS domain SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 Gene3D G3DSA:3.60.40.10 323 631 5.0E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS21890 505e04f7cf9f8e031dc9da93d542cd76 793 Gene3D G3DSA:3.30.450.20 23 141 6.0E-8 T 28-03-2018 SMD44_RS06355 c2d3dfc245040274c24f0d855fb00d78 290 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 269 4.5E-75 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMD44_RS06355 c2d3dfc245040274c24f0d855fb00d78 290 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 276 17.703 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMD44_RS06355 c2d3dfc245040274c24f0d855fb00d78 290 Pfam PF02673 Bacitracin resistance protein BacA 7 271 2.0E-82 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMD44_RS17830 c4b3da45c41fef87f86501db602cfd4d 183 Gene3D G3DSA:3.40.430.10 2 180 2.3E-37 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS17830 c4b3da45c41fef87f86501db602cfd4d 183 SUPERFAMILY SSF53597 4 182 2.36E-30 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS17830 c4b3da45c41fef87f86501db602cfd4d 183 Pfam PF01872 RibD C-terminal domain 4 176 2.3E-25 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS42865 69e5b1f5aed84ab629790ab88a4deea8 149 Pfam PF13581 Histidine kinase-like ATPase domain 14 140 1.1E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42865 69e5b1f5aed84ab629790ab88a4deea8 149 SUPERFAMILY SSF55874 38 139 7.61E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42865 69e5b1f5aed84ab629790ab88a4deea8 149 Gene3D G3DSA:3.30.565.10 4 149 7.2E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04875 f042c424dd6ce43c2d3b92cb990cc3cd 747 Gene3D G3DSA:1.50.10.10 214 615 7.2E-51 T 28-03-2018 SMD44_RS04875 f042c424dd6ce43c2d3b92cb990cc3cd 747 Gene3D G3DSA:2.60.40.1180 616 726 1.2E-15 T 28-03-2018 SMD44_RS04875 f042c424dd6ce43c2d3b92cb990cc3cd 747 SUPERFAMILY SSF48208 244 685 2.49E-36 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 37.961 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.5E-72 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.1E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.1E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.1E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 Gene3D G3DSA:3.90.930.12 2 83 4.3E-28 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 Pfam PF00347 Ribosomal protein L6 92 165 1.4E-18 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 Pfam PF00347 Ribosomal protein L6 11 83 8.2E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 SUPERFAMILY SSF56053 1 83 3.01E-26 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 PIRSF PIRSF002162 1 178 6.9E-48 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 Gene3D G3DSA:3.90.930.12 84 179 1.7E-37 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25580 f26538755b6589b8ce690e4c5c1eae8c 179 SUPERFAMILY SSF56053 84 177 4.84E-35 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS12770 7ef78eb233294ec8eb8ccd89e84b9b47 333 Gene3D G3DSA:3.40.47.10 171 332 3.6E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12770 7ef78eb233294ec8eb8ccd89e84b9b47 333 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 12 331 6.4E-110 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS12770 7ef78eb233294ec8eb8ccd89e84b9b47 333 SUPERFAMILY SSF53901 10 331 2.04E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12770 7ef78eb233294ec8eb8ccd89e84b9b47 333 Gene3D G3DSA:3.40.47.10 2 170 9.1E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS12770 7ef78eb233294ec8eb8ccd89e84b9b47 333 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 4.8E-25 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS12770 7ef78eb233294ec8eb8ccd89e84b9b47 333 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 332 60.019 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS12770 7ef78eb233294ec8eb8ccd89e84b9b47 333 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 331 4.8E-31 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS12680 4b266c97ffd6dc7b755032829781a3db 382 Pfam PF04332 Protein of unknown function (DUF475) 44 361 3.8E-140 T 28-03-2018 IPR007427 Protein of unknown function DUF475 SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 SUPERFAMILY SSF49785 595 738 6.38E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 SUPERFAMILY SSF51126 192 523 9.43E-34 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 Pfam PF00754 F5/8 type C domain 609 729 2.9E-15 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 SMART SM00710 336 358 330.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 SMART SM00710 513 543 2800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 SMART SM00710 387 410 2100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 SMART SM00710 411 435 67.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 SMART SM00710 360 382 1800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 Gene3D G3DSA:2.60.120.260 588 740 6.4E-27 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 Gene3D G3DSA:2.60.120.260 46 190 6.6E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 Gene3D G3DSA:2.160.20.10 191 566 2.7E-35 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS38215 1b1322a1e9a03d2e2d42abea3ec13ab6 740 Pfam PF12708 Pectate lyase superfamily protein 207 424 7.9E-13 T 28-03-2018 IPR024535 Pectate lyase superfamily protein SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 379 5.7E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 337 4.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 4.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 4.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 Pfam PF07730 Histidine kinase 183 250 5.3E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 Gene3D G3DSA:3.30.565.10 165 380 1.0E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 Gene3D G3DSA:3.30.450.40 19 164 1.4E-33 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 SUPERFAMILY SSF55781 12 179 8.94E-30 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 SUPERFAMILY SSF55874 252 379 1.15E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 SMART SM00387 287 381 1.7E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 SMART SM00065 24 176 2.3E-18 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS09310 ed74cd23d7b741765edfe51b9e919e2e 381 Pfam PF13185 GAF domain 23 166 9.8E-21 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS29645 86155fe61d43e0d25fb9e304a89e27b0 292 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 67 182 4.8E-11 T 28-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain SMD44_RS29645 86155fe61d43e0d25fb9e304a89e27b0 292 Gene3D G3DSA:3.20.20.190 30 292 7.5E-49 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS29645 86155fe61d43e0d25fb9e304a89e27b0 292 SMART SM00148 43 184 5.0E-7 T 28-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain SMD44_RS29645 86155fe61d43e0d25fb9e304a89e27b0 292 SUPERFAMILY SSF51695 36 292 8.37E-49 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS23970 b636e04b7733a53aa90a9b022402457d 374 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 17 371 44.116 T 28-03-2018 IPR023763 DNA integrity scanning protein, DisA SMD44_RS23970 b636e04b7733a53aa90a9b022402457d 374 Pfam PF12826 Helix-hairpin-helix motif 324 361 1.3E-6 T 28-03-2018 SMD44_RS23970 b636e04b7733a53aa90a9b022402457d 374 Pfam PF10635 DisA bacterial checkpoint controller linker region 155 297 3.6E-53 T 28-03-2018 IPR018906 DNA integrity scanning, DisA, linker region SMD44_RS23970 b636e04b7733a53aa90a9b022402457d 374 Gene3D G3DSA:1.10.150.20 307 371 9.3E-10 T 28-03-2018 SMD44_RS23970 b636e04b7733a53aa90a9b022402457d 374 SUPERFAMILY SSF47781 298 366 5.19E-12 T 28-03-2018 IPR010994 RuvA domain 2-like SMD44_RS23970 b636e04b7733a53aa90a9b022402457d 374 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 38 151 4.1E-22 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SMD44_RS23970 b636e04b7733a53aa90a9b022402457d 374 Gene3D G3DSA:3.40.1700.10 19 155 2.9E-25 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SMD44_RS23970 b636e04b7733a53aa90a9b022402457d 374 SUPERFAMILY SSF143597 32 154 2.35E-26 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 Pfam PF00561 alpha/beta hydrolase fold 37 167 9.8E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 8 313 1.3E-90 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 SUPERFAMILY SSF53474 4 307 1.06E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 Gene3D G3DSA:3.40.50.1820 1 314 1.3E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 PIRSF PIRSF006431 1 315 7.1E-109 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 1.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 1.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 110 124 1.7E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 62 73 1.7E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS10435 15ac11688c6e04ffbac85c3c26e67f4b 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 36 44 1.7E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 128 142 3.1E-55 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 273 288 3.1E-55 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 303 322 3.1E-55 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 197 216 3.1E-55 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 3.1E-55 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 159 178 3.1E-55 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 SMART SM01004 7 329 8.9E-216 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 SUPERFAMILY SSF51569 5 329 1.32E-129 T 28-03-2018 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 PIRSF PIRSF001415 1 329 7.3E-146 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 10 327 4.2E-136 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMD44_RS24160 fe8ce2a9d30cff21ebc5697cd72eddae 329 Gene3D G3DSA:3.20.20.70 1 329 4.2E-145 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS11735 f35bc8cda7e085de962ca1bc4a8c1db5 363 Gene3D G3DSA:3.40.50.1000 51 349 1.5E-8 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS11735 f35bc8cda7e085de962ca1bc4a8c1db5 363 Pfam PF12710 haloacid dehalogenase-like hydrolase 127 244 8.0E-8 T 28-03-2018 SMD44_RS11735 f35bc8cda7e085de962ca1bc4a8c1db5 363 SUPERFAMILY SSF56784 35 305 3.46E-14 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS25955 ba2ef2a26f07fad0a1fa53401826bf21 412 Pfam PF00877 NlpC/P60 family 312 401 2.6E-25 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS25955 ba2ef2a26f07fad0a1fa53401826bf21 412 Gene3D G3DSA:3.90.1720.10 293 405 3.4E-40 T 28-03-2018 SMD44_RS25955 ba2ef2a26f07fad0a1fa53401826bf21 412 SUPERFAMILY SSF54001 298 410 2.11E-42 T 28-03-2018 SMD44_RS16180 c8b1dc9b2f656fd31614fc4c82b26300 286 Gene3D G3DSA:3.40.50.300 32 285 4.8E-42 T 28-03-2018 SMD44_RS16180 c8b1dc9b2f656fd31614fc4c82b26300 286 SMART SM00382 90 273 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16180 c8b1dc9b2f656fd31614fc4c82b26300 286 Pfam PF00005 ABC transporter 82 215 3.4E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS16180 c8b1dc9b2f656fd31614fc4c82b26300 286 SUPERFAMILY SSF52540 77 278 2.93E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16180 c8b1dc9b2f656fd31614fc4c82b26300 286 ProSitePatterns PS00211 ABC transporters family signature. 188 202 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS08670 3564ce7424c6111608a25a7d19bc64a6 271 Pfam PF10099 Anti-sigma-K factor rskA 78 261 8.2E-32 T 28-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 SMD44_RS08670 3564ce7424c6111608a25a7d19bc64a6 271 Pfam PF13490 Putative zinc-finger 26 55 7.1E-7 T 28-03-2018 IPR027383 Putative zinc-finger SMD44_RS17000 049ca897fad9d2fba5869ff2efd41373 147 SUPERFAMILY SSF55729 42 146 4.63E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS17000 049ca897fad9d2fba5869ff2efd41373 147 Gene3D G3DSA:3.40.630.30 41 146 2.3E-20 T 28-03-2018 SMD44_RS17000 049ca897fad9d2fba5869ff2efd41373 147 Pfam PF00583 Acetyltransferase (GNAT) family 40 124 7.8E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS20250 75d3aecb1cf0c5254903251feeabc9ad 97 Gene3D G3DSA:3.30.70.100 1 97 1.6E-18 T 28-03-2018 SMD44_RS20250 75d3aecb1cf0c5254903251feeabc9ad 97 SUPERFAMILY SSF54909 2 94 8.58E-16 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS20250 75d3aecb1cf0c5254903251feeabc9ad 97 SMART SM00886 2 97 8.8E-21 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel SMD44_RS20250 75d3aecb1cf0c5254903251feeabc9ad 97 Pfam PF07876 Stress responsive A/B Barrel Domain 2 96 6.5E-21 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel SMD44_RS09450 0c604240d44077f81fe656348648446b 298 Pfam PF04116 Fatty acid hydroxylase superfamily 87 218 2.1E-27 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 Gene3D G3DSA:3.40.50.300 1 271 5.5E-50 T 28-03-2018 SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 Gene3D G3DSA:3.40.50.300 335 535 1.2E-34 T 28-03-2018 SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 SUPERFAMILY SSF52540 364 534 1.94E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 SMART SM00382 369 533 5.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 SMART SM00382 29 233 4.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 Pfam PF00005 ABC transporter 21 188 3.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 Pfam PF00005 ABC transporter 364 487 1.5E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS31460 e80e34dd659b517998b220f8cc9a7af2 536 SUPERFAMILY SSF52540 4 233 4.3E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21010 334c9d23738deece0dd3d7c95f39ab3b 909 Pfam PF00905 Penicillin binding protein transpeptidase domain 468 747 1.7E-29 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS21010 334c9d23738deece0dd3d7c95f39ab3b 909 Gene3D G3DSA:3.40.710.10 381 841 1.3E-91 T 28-03-2018 SMD44_RS21010 334c9d23738deece0dd3d7c95f39ab3b 909 Gene3D G3DSA:1.10.3810.10 167 378 3.0E-64 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS21010 334c9d23738deece0dd3d7c95f39ab3b 909 SUPERFAMILY SSF56601 345 365 2.21E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS21010 334c9d23738deece0dd3d7c95f39ab3b 909 SUPERFAMILY SSF56601 551 803 2.21E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS21010 334c9d23738deece0dd3d7c95f39ab3b 909 SUPERFAMILY SSF56601 395 524 2.21E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS21010 334c9d23738deece0dd3d7c95f39ab3b 909 SUPERFAMILY SSF53955 165 381 7.59E-59 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS21010 334c9d23738deece0dd3d7c95f39ab3b 909 Pfam PF00912 Transglycosylase 181 359 7.6E-55 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS33680 ccc2bb0fa113cd11c06b591d1546a867 241 Gene3D G3DSA:3.30.420.10 69 240 4.6E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS33680 ccc2bb0fa113cd11c06b591d1546a867 241 Pfam PF00665 Integrase core domain 75 188 1.3E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SMD44_RS33680 ccc2bb0fa113cd11c06b591d1546a867 241 SUPERFAMILY SSF53098 69 229 1.03E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 SUPERFAMILY SSF46689 6 70 1.9E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 Gene3D G3DSA:1.10.260.40 37 85 3.8E-9 T 28-03-2018 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 Gene3D G3DSA:1.10.10.60 2 36 1.6E-12 T 28-03-2018 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 PRINTS PR00400 Tetracycline repressor protein signature 135 154 1.3E-8 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 PRINTS PR00400 Tetracycline repressor protein signature 27 50 1.3E-8 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 PRINTS PR00400 Tetracycline repressor protein signature 192 206 1.3E-8 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 SUPERFAMILY SSF48498 75 206 4.63E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 81 206 3.6E-9 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS09480 b432adf8845360466a125b89a9706e1c 213 Gene3D G3DSA:1.10.357.10 86 208 1.6E-14 T 28-03-2018 SMD44_RS40705 903a1bdf90a74bddad31c9edee2b7876 496 Gene3D G3DSA:1.25.40.10 18 282 1.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40705 903a1bdf90a74bddad31c9edee2b7876 496 SUPERFAMILY SSF48452 43 71 2.66E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40705 903a1bdf90a74bddad31c9edee2b7876 496 SUPERFAMILY SSF48452 105 171 2.66E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40705 903a1bdf90a74bddad31c9edee2b7876 496 PRINTS PR00313 NodO calcium binding signature 416 424 9.2E-7 T 28-03-2018 SMD44_RS40705 903a1bdf90a74bddad31c9edee2b7876 496 PRINTS PR00313 NodO calcium binding signature 477 486 9.2E-7 T 28-03-2018 SMD44_RS40705 903a1bdf90a74bddad31c9edee2b7876 496 PRINTS PR00313 NodO calcium binding signature 435 443 9.2E-7 T 28-03-2018 SMD44_RS40705 903a1bdf90a74bddad31c9edee2b7876 496 PRINTS PR00313 NodO calcium binding signature 394 405 9.2E-7 T 28-03-2018 SMD44_RS40705 903a1bdf90a74bddad31c9edee2b7876 496 SUPERFAMILY SSF51120 392 489 8.63E-7 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 13 374 41.152 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 Gene3D G3DSA:3.40.50.20 3 166 3.3E-45 T 28-03-2018 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 SUPERFAMILY SSF52440 12 154 6.23E-34 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 316 344 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 Gene3D G3DSA:3.30.470.20 233 380 9.6E-39 T 28-03-2018 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 Pfam PF07478 D-ala D-ala ligase C-terminus 164 371 4.0E-66 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 Gene3D G3DSA:3.30.1490.20 175 232 8.6E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 Pfam PF01820 D-ala D-ala ligase N-terminus 14 145 8.2E-31 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 14 373 7.7E-104 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 SUPERFAMILY SSF56059 156 376 3.71E-53 T 28-03-2018 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 PIRSF PIRSF039102 11 380 1.0E-109 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS30285 e0625ef73544a02feca956c2cb315d82 381 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 123 134 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS29245 f26a1c5d09ed475c5083d8592f9aa34f 280 Gene3D G3DSA:1.10.3720.10 2 266 2.9E-42 T 28-03-2018 SMD44_RS29245 f26a1c5d09ed475c5083d8592f9aa34f 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 268 4.2E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS29245 f26a1c5d09ed475c5083d8592f9aa34f 280 SUPERFAMILY SSF161098 8 276 1.44E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS18605 2faa85f50908005d934563120af941e2 218 Gene3D G3DSA:3.40.50.1000 79 216 3.2E-16 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18605 2faa85f50908005d934563120af941e2 218 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 167 4.1E-12 T 28-03-2018 SMD44_RS18605 2faa85f50908005d934563120af941e2 218 SUPERFAMILY SSF56784 62 198 3.36E-35 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18605 2faa85f50908005d934563120af941e2 218 SUPERFAMILY SSF56784 8 33 3.36E-35 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18605 2faa85f50908005d934563120af941e2 218 Gene3D G3DSA:1.10.150.240 25 78 1.4E-7 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS23745 e1545265e39a2ac445801f7c0888ae8e 377 Gene3D G3DSA:3.40.50.1820 111 373 2.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23745 e1545265e39a2ac445801f7c0888ae8e 377 SUPERFAMILY SSF53474 114 370 3.44E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23745 e1545265e39a2ac445801f7c0888ae8e 377 Pfam PF00756 Putative esterase 134 350 2.9E-12 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 SMART SM00382 346 543 0.0049 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Pfam PF14520 Helix-hairpin-helix domain 91 140 4.1E-7 T 28-03-2018 SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Gene3D G3DSA:3.40.50.300 299 501 7.0E-38 T 28-03-2018 SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 SUPERFAMILY SSF52540 442 509 6.64E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 SUPERFAMILY SSF52540 550 716 6.64E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Pfam PF14490 Helix-hairpin-helix containing domain 141 231 3.9E-30 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Gene3D G3DSA:1.10.150.280 123 208 1.1E-6 T 28-03-2018 SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 SUPERFAMILY SSF52540 181 477 2.37E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Pfam PF13604 AAA domain 333 511 5.7E-45 T 28-03-2018 SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Gene3D G3DSA:3.40.50.300 502 716 2.7E-34 T 28-03-2018 SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Pfam PF13538 UvrD-like helicase C-terminal domain 655 703 5.7E-20 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 SUPERFAMILY SSF47781 82 159 2.78E-10 T 28-03-2018 IPR010994 RuvA domain 2-like SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 1 732 29.003 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 Gene3D G3DSA:1.10.150.20 90 122 0.0036 T 28-03-2018 SMD44_RS14765 10723e259fffa006480e26f626fb5f7d 735 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 5 728 7.4E-200 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 SMART SM00487 71 267 1.5E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Gene3D G3DSA:3.40.50.300 59 257 5.5E-32 T 28-03-2018 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Gene3D G3DSA:3.40.50.300 259 454 1.3E-44 T 28-03-2018 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 64 666 2.6E-229 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 SMART SM00956 463 569 3.4E-46 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Pfam PF00570 HRDC domain 602 666 3.7E-21 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 SMART SM00490 300 381 6.0E-23 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Pfam PF16124 RecQ zinc-binding 393 456 3.9E-18 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Pfam PF00270 DEAD/DEAH box helicase 79 235 3.5E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 SUPERFAMILY SSF47819 596 669 2.4E-22 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Pfam PF09382 RQC domain 458 572 2.9E-35 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 SMART SM00341 596 671 2.4E-8 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Gene3D G3DSA:1.10.150.80 584 671 6.3E-24 T 28-03-2018 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 SUPERFAMILY SSF52540 257 514 3.65E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 SUPERFAMILY SSF52540 63 248 6.66E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Gene3D G3DSA:1.10.10.10 455 583 2.1E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 65 519 2.3E-150 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 SMD44_RS25090 0be9315ff02cd71e4f78b540ca677b04 671 Pfam PF00271 Helicase conserved C-terminal domain 274 380 1.5E-14 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS06515 8b5e92a3e18afac5a6261dee2026cb4c 233 SUPERFAMILY SSF50475 14 205 4.52E-61 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS06515 8b5e92a3e18afac5a6261dee2026cb4c 233 Gene3D G3DSA:2.30.110.10 1 203 4.7E-51 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS06515 8b5e92a3e18afac5a6261dee2026cb4c 233 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 33 183 2.3E-50 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 45 282 1.2E-78 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 SUPERFAMILY SSF63829 39 306 2.4E-62 T 28-03-2018 SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 Gene3D G3DSA:2.120.10.30 34 312 4.9E-38 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 263 281 1.6E-39 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 46 63 1.6E-39 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 183 203 1.6E-39 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 160 182 1.6E-39 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 221 238 1.6E-39 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS05240 090b986e94a3e5435bd3b6d36e24cca9 312 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 119 140 1.6E-39 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMD44_RS17735 4074ca6c6d47479958d293b219155b2f 254 Pfam PF01522 Polysaccharide deacetylase 64 186 7.7E-27 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS17735 4074ca6c6d47479958d293b219155b2f 254 SUPERFAMILY SSF88713 61 249 8.16E-51 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS17735 4074ca6c6d47479958d293b219155b2f 254 Gene3D G3DSA:3.20.20.370 58 252 5.5E-46 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 SUPERFAMILY SSF52317 1 186 4.59E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 3.1E-9 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 3.1E-9 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 185 4.7E-56 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 Pfam PF00117 Glutamine amidotransferase class-I 4 185 1.5E-48 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.1E-13 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 2.1E-13 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.1E-13 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00097 Anthranilate synthase component II signature 99 107 5.2E-29 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00097 Anthranilate synthase component II signature 119 131 5.2E-29 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00097 Anthranilate synthase component II signature 74 85 5.2E-29 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00097 Anthranilate synthase component II signature 164 177 5.2E-29 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00097 Anthranilate synthase component II signature 3 17 5.2E-29 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 PRINTS PR00097 Anthranilate synthase component II signature 48 57 5.2E-29 T 28-03-2018 SMD44_RS15240 a32563c6aa229af4775c2b1e12431684 202 Gene3D G3DSA:3.40.50.880 1 191 5.7E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS17315 4a2a970f67cd96767e7c5ff461ed25f7 938 Pfam PF01804 Penicillin amidase 67 927 2.0E-244 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 SMD44_RS17315 4a2a970f67cd96767e7c5ff461ed25f7 938 SUPERFAMILY SSF56235 321 938 6.17E-212 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS17315 4a2a970f67cd96767e7c5ff461ed25f7 938 SUPERFAMILY SSF56235 62 256 6.17E-212 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS17315 4a2a970f67cd96767e7c5ff461ed25f7 938 PIRSF PIRSF001227 24 938 8.6E-283 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 SMD44_RS17315 4a2a970f67cd96767e7c5ff461ed25f7 938 Gene3D G3DSA:1.10.439.10 37 206 1.8E-54 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 SMD44_RS17315 4a2a970f67cd96767e7c5ff461ed25f7 938 Gene3D G3DSA:3.60.20.10 731 926 1.4E-29 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS17315 4a2a970f67cd96767e7c5ff461ed25f7 938 Gene3D G3DSA:3.60.20.10 333 718 5.0E-113 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS07250 8112e78933134b9810c9ee1f914eac86 370 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 344 47.001 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD44_RS07250 8112e78933134b9810c9ee1f914eac86 370 SUPERFAMILY SSF51395 1 363 2.66E-103 T 28-03-2018 SMD44_RS07250 8112e78933134b9810c9ee1f914eac86 370 Gene3D G3DSA:3.20.20.70 1 370 1.6E-86 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS07250 8112e78933134b9810c9ee1f914eac86 370 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 SMD44_RS07250 8112e78933134b9810c9ee1f914eac86 370 Pfam PF01180 Dihydroorotate dehydrogenase 50 348 1.5E-92 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 SMD44_RS07250 8112e78933134b9810c9ee1f914eac86 370 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 5 365 4.2E-126 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD44_RS06525 0b0c778b8737cf58ac5699102dffea87 326 SUPERFAMILY SSF103481 210 313 4.84E-12 T 28-03-2018 SMD44_RS06525 0b0c778b8737cf58ac5699102dffea87 326 SUPERFAMILY SSF103481 57 165 3.66E-8 T 28-03-2018 SMD44_RS06525 0b0c778b8737cf58ac5699102dffea87 326 Pfam PF00892 EamA-like transporter family 21 162 2.1E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS06525 0b0c778b8737cf58ac5699102dffea87 326 Pfam PF00892 EamA-like transporter family 173 309 3.4E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS28090 e78befda81932761f52016eb9c0f55a1 80 Gene3D G3DSA:3.40.30.10 2 80 4.0E-17 T 28-03-2018 SMD44_RS28090 e78befda81932761f52016eb9c0f55a1 80 SUPERFAMILY SSF52833 4 72 1.66E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS28090 e78befda81932761f52016eb9c0f55a1 80 Pfam PF00462 Glutaredoxin 5 60 1.7E-12 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SMD44_RS28090 e78befda81932761f52016eb9c0f55a1 80 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 4 79 6.4E-33 T 28-03-2018 IPR011915 Glutaredoxin-like protein, actinobacteria SMD44_RS28090 e78befda81932761f52016eb9c0f55a1 80 ProSitePatterns PS00194 Thioredoxin family active site. 5 23 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMD44_RS30705 0c46a877113da9c44765da0ca9264ef0 185 Pfam PF08719 Domain of unknown function (DUF1768) 27 185 8.1E-51 T 28-03-2018 IPR012816 NADAR SMD44_RS30705 0c46a877113da9c44765da0ca9264ef0 185 SUPERFAMILY SSF143990 20 185 1.44E-48 T 28-03-2018 SMD44_RS30705 0c46a877113da9c44765da0ca9264ef0 185 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 25 185 4.0E-51 T 28-03-2018 IPR012816 NADAR SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 Gene3D G3DSA:1.10.10.10 192 249 3.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 PRINTS PR00046 Major sigma-70 factor signature 207 219 5.2E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 PRINTS PR00046 Major sigma-70 factor signature 224 239 5.2E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 PRINTS PR00046 Major sigma-70 factor signature 60 73 5.2E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 SUPERFAMILY SSF88659 108 185 3.23E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 Pfam PF04545 Sigma-70, region 4 204 251 3.0E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 33 253 1.4E-75 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 SUPERFAMILY SSF88946 32 104 4.71E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 Pfam PF04542 Sigma-70 region 2 36 104 5.5E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 Gene3D G3DSA:1.10.10.10 113 159 2.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 253 3.0E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 Gene3D G3DSA:1.10.1740.10 8 112 4.6E-16 T 28-03-2018 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 SUPERFAMILY SSF88659 179 254 1.25E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS37795 fac4c89a96449f62b0ff643b06132fd5 264 Pfam PF04539 Sigma-70 region 3 115 178 3.3E-7 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS29025 a800d25169d4b5474d520f59742b5d5c 146 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 136 5.7E-44 T 28-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 SMD44_RS29025 a800d25169d4b5474d520f59742b5d5c 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 7.3E-21 T 28-03-2018 SMD44_RS29025 a800d25169d4b5474d520f59742b5d5c 146 Gene3D G3DSA:3.10.180.10 1 141 4.0E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS29025 a800d25169d4b5474d520f59742b5d5c 146 SUPERFAMILY SSF54593 1 138 2.82E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS09625 b107cf78c90f5f7524f13581ee76907e 202 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 202 2.1E-69 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMD44_RS09625 b107cf78c90f5f7524f13581ee76907e 202 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 202 4.9E-58 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMD44_RS09625 b107cf78c90f5f7524f13581ee76907e 202 PIRSF PIRSF015617 1 202 7.2E-65 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMD44_RS09625 b107cf78c90f5f7524f13581ee76907e 202 Gene3D G3DSA:3.40.50.300 7 202 1.1E-62 T 28-03-2018 SMD44_RS09625 b107cf78c90f5f7524f13581ee76907e 202 SUPERFAMILY SSF52540 12 202 6.73E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37315 8e983bcb692276d923fb63801ef2c029 220 Gene3D G3DSA:2.40.260.10 54 220 6.6E-26 T 28-03-2018 IPR023365 Sortase domain SMD44_RS37315 8e983bcb692276d923fb63801ef2c029 220 Pfam PF04203 Sortase family 78 217 3.6E-15 T 28-03-2018 IPR005754 Sortase family SMD44_RS37315 8e983bcb692276d923fb63801ef2c029 220 SUPERFAMILY SSF63817 75 218 1.84E-12 T 28-03-2018 IPR023365 Sortase domain SMD44_RS24080 624759c7d5c9ab86bc773f5217c06bf8 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 63 186 7.0E-18 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS24080 624759c7d5c9ab86bc773f5217c06bf8 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 186 1.9E-27 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS24080 624759c7d5c9ab86bc773f5217c06bf8 214 Gene3D G3DSA:3.40.50.1000 75 214 4.0E-31 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS24080 624759c7d5c9ab86bc773f5217c06bf8 214 Gene3D G3DSA:1.10.150.240 29 74 1.7E-20 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS24080 624759c7d5c9ab86bc773f5217c06bf8 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 86 181 2.2E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS24080 624759c7d5c9ab86bc773f5217c06bf8 214 SUPERFAMILY SSF56784 2 213 1.05E-51 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS24080 624759c7d5c9ab86bc773f5217c06bf8 214 Gene3D G3DSA:3.40.50.1000 1 28 0.1 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 Gene3D G3DSA:1.20.1250.20 1 191 2.7E-27 T 28-03-2018 SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 PRINTS PR01035 Tetracycline resistance protein signature 39 58 7.4E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 PRINTS PR01035 Tetracycline resistance protein signature 287 307 7.4E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 PRINTS PR01035 Tetracycline resistance protein signature 9 25 7.4E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 PRINTS PR01035 Tetracycline resistance protein signature 70 94 7.4E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 PRINTS PR01035 Tetracycline resistance protein signature 124 146 7.4E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 Pfam PF07690 Major Facilitator Superfamily 7 337 1.7E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 Gene3D G3DSA:1.20.1250.20 192 387 7.6E-14 T 28-03-2018 SMD44_RS15910 4440bd563243e2c42f55653568ab0c6c 405 SUPERFAMILY SSF103473 2 377 1.27E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 SMART SM00354 2 72 4.2E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 Pfam PF13377 Periplasmic binding protein-like domain 168 333 5.6E-34 T 28-03-2018 SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 Gene3D G3DSA:3.40.50.2300 175 335 6.4E-41 T 28-03-2018 SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.0E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 SUPERFAMILY SSF47413 2 60 1.69E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 Gene3D G3DSA:3.40.50.2300 55 174 8.1E-30 T 28-03-2018 SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 Gene3D G3DSA:1.10.260.40 1 54 3.1E-23 T 28-03-2018 SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 SUPERFAMILY SSF53822 63 333 3.2E-61 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS37060 c7c50dc0fcf25144487ee0d975e916e9 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 SMD44_RS27065 6527ffb68536933f7eae4c9bb315f29c 304 SMART SM00530 24 97 1.7E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS27065 6527ffb68536933f7eae4c9bb315f29c 304 Gene3D G3DSA:1.10.260.40 9 116 4.8E-18 T 28-03-2018 SMD44_RS27065 6527ffb68536933f7eae4c9bb315f29c 304 SUPERFAMILY SSF47413 44 96 3.85E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS27065 6527ffb68536933f7eae4c9bb315f29c 304 Pfam PF13560 Helix-turn-helix domain 20 100 2.5E-18 T 28-03-2018 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 112 176 2.8E-7 T 28-03-2018 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 PRINTS PR01185 Integrin alpha subunit signature 103 124 9.9E-5 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 PRINTS PR01185 Integrin alpha subunit signature 31 55 9.9E-5 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 Gene3D G3DSA:2.130.10.130 198 331 8.9E-11 T 28-03-2018 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 Gene3D G3DSA:2.130.10.130 16 186 3.6E-18 T 28-03-2018 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 Gene3D G3DSA:2.130.10.130 332 474 4.1E-16 T 28-03-2018 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 Pfam PF01839 FG-GAP repeat 339 366 1.0E-6 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 Pfam PF01839 FG-GAP repeat 39 70 2.1E-7 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 SMART SM00191 260 320 200.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 SMART SM00191 28 87 0.0019 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 SMART SM00191 334 394 1.4E-6 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS19395 fa257d19cfce12544e5357dbcf205729 476 SUPERFAMILY SSF69318 39 437 2.09E-52 T 28-03-2018 SMD44_RS41510 9c19d0cdcc4f61e754218c2781045691 391 SUPERFAMILY SSF51412 8 373 7.98E-103 T 28-03-2018 SMD44_RS41510 9c19d0cdcc4f61e754218c2781045691 391 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 372 1.1E-119 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMD44_RS41510 9c19d0cdcc4f61e754218c2781045691 391 PIRSF PIRSF000130 95 385 4.4E-94 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMD44_RS41510 9c19d0cdcc4f61e754218c2781045691 391 PIRSF PIRSF000130 1 99 2.7E-20 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMD44_RS41510 9c19d0cdcc4f61e754218c2781045691 391 SMART SM01240 9 372 1.4E-156 T 28-03-2018 SMD44_RS41510 9c19d0cdcc4f61e754218c2781045691 391 Gene3D G3DSA:3.20.20.70 3 379 4.8E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS21005 0c487f958647f7207c209fa80c01be43 517 Pfam PF09594 Glycosyltransferase family 87 134 372 1.8E-14 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD44_RS21005 0c487f958647f7207c209fa80c01be43 517 PIRSF PIRSF010361 27 486 1.7E-144 T 28-03-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane SMD44_RS29395 57e118def40bb7094d74f050d15e9f35 313 SUPERFAMILY SSF53613 1 297 1.71E-56 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS29395 57e118def40bb7094d74f050d15e9f35 313 Gene3D G3DSA:3.40.1190.20 1 305 3.9E-49 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS29395 57e118def40bb7094d74f050d15e9f35 313 Pfam PF00294 pfkB family carbohydrate kinase 28 296 1.2E-45 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS29395 57e118def40bb7094d74f050d15e9f35 313 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD44_RS01145 3fff840148dc96896b4c94e13200ec11 179 Pfam PF08044 Domain of unknown function (DUF1707) 8 60 9.8E-18 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 SMD44_RS22230 34b75e46fe0a3c6e96e03bf588b5b20e 496 SUPERFAMILY SSF103473 19 216 2.22E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS22230 34b75e46fe0a3c6e96e03bf588b5b20e 496 SUPERFAMILY SSF103473 273 493 2.22E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS22230 34b75e46fe0a3c6e96e03bf588b5b20e 496 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 38 450 4.1E-74 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS22230 34b75e46fe0a3c6e96e03bf588b5b20e 496 Gene3D G3DSA:1.20.1250.20 277 495 1.2E-27 T 28-03-2018 SMD44_RS22230 34b75e46fe0a3c6e96e03bf588b5b20e 496 Gene3D G3DSA:1.20.1250.20 30 226 4.9E-28 T 28-03-2018 SMD44_RS22230 34b75e46fe0a3c6e96e03bf588b5b20e 496 Pfam PF07690 Major Facilitator Superfamily 42 435 8.3E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS25680 91fb00c61e586372ef86c32cf50e4f6d 316 Pfam PF04087 Domain of unknown function (DUF389) 145 289 1.4E-30 T 28-03-2018 IPR005240 Protein of unknown function DUF389 SMD44_RS25680 91fb00c61e586372ef86c32cf50e4f6d 316 TIGRFAM TIGR00271 TIGR00271: uncharacterized hydrophobic domain 112 295 1.4E-57 T 28-03-2018 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 Gene3D G3DSA:1.25.40.10 948 1105 1.6E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 SUPERFAMILY SSF46894 857 939 2.83E-9 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 SMART SM00862 868 939 1.9E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 SUPERFAMILY SSF56784 1267 1499 6.34E-16 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 SMART SM01043 946 1090 6.0E-29 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 Gene3D G3DSA:3.40.50.1000 1329 1501 3.3E-14 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 Pfam PF07714 Protein tyrosine kinase 647 760 1.5E-7 T 28-03-2018 IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain GO:0004672|GO:0006468 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 Gene3D G3DSA:1.10.510.10 709 854 4.1E-11 T 28-03-2018 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 SUPERFAMILY SSF56112 634 797 3.22E-16 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 Pfam PF03704 Bacterial transcriptional activator domain 946 1089 4.1E-26 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 SUPERFAMILY SSF48452 941 1103 1.09E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 Gene3D G3DSA:3.30.200.20 585 708 9.3E-5 T 28-03-2018 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 Pfam PF00486 Transcriptional regulatory protein, C terminal 875 939 1.3E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS12990 3f567a63ec17d86d47687725d5853650 1501 Gene3D G3DSA:1.10.10.10 858 947 8.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 5.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 172 0.0028 T 28-03-2018 SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 Gene3D G3DSA:3.40.50.720 1 45 5.3E-11 T 28-03-2018 SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 Gene3D G3DSA:3.40.50.720 46 246 2.4E-58 T 28-03-2018 SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 242 4.8E-61 T 28-03-2018 SMD44_RS03435 f7f42b7ddae7b455a85c723e428d6934 248 SUPERFAMILY SSF51735 6 242 5.37E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS27910 c22092df0a1bd0a598f13d69adfbedf9 371 SUPERFAMILY SSF144083 307 368 1.57E-18 T 28-03-2018 SMD44_RS27910 c22092df0a1bd0a598f13d69adfbedf9 371 SUPERFAMILY SSF143865 29 302 1.44E-62 T 28-03-2018 SMD44_RS27910 c22092df0a1bd0a598f13d69adfbedf9 371 Gene3D G3DSA:1.20.58.340 304 371 9.3E-17 T 28-03-2018 SMD44_RS27910 c22092df0a1bd0a598f13d69adfbedf9 371 Gene3D G3DSA:1.20.58.340 182 303 8.4E-32 T 28-03-2018 SMD44_RS27910 c22092df0a1bd0a598f13d69adfbedf9 371 Pfam PF01544 CorA-like Mg2+ transporter protein 68 359 1.2E-57 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD44_RS27910 c22092df0a1bd0a598f13d69adfbedf9 371 Gene3D G3DSA:3.30.460.20 23 174 7.9E-38 T 28-03-2018 SMD44_RS27540 b5d2b429ade69e3d6b1f63b579381b83 403 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 401 3.3E-121 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SMD44_RS27540 b5d2b429ade69e3d6b1f63b579381b83 403 Pfam PF13742 OB-fold nucleic acid binding domain 12 105 5.7E-17 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 SMD44_RS27540 b5d2b429ade69e3d6b1f63b579381b83 403 Pfam PF02601 Exonuclease VII, large subunit 129 350 3.5E-62 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SMD44_RS27540 b5d2b429ade69e3d6b1f63b579381b83 403 Pfam PF02601 Exonuclease VII, large subunit 333 399 1.4E-10 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SMD44_RS27540 b5d2b429ade69e3d6b1f63b579381b83 403 Gene3D G3DSA:2.40.50.140 23 110 2.5E-4 T 28-03-2018 SMD44_RS27540 b5d2b429ade69e3d6b1f63b579381b83 403 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 402 25.408 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SMD44_RS22205 654f8bfabad6822145a48c5374b4fc7e 338 SUPERFAMILY SSF52266 91 254 8.49E-8 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS22205 654f8bfabad6822145a48c5374b4fc7e 338 Gene3D G3DSA:3.40.50.1110 59 302 1.9E-11 T 28-03-2018 SMD44_RS19715 979cda5a9434d868d889b6caf9128543 122 SUPERFAMILY SSF46785 20 115 2.54E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19715 979cda5a9434d868d889b6caf9128543 122 Pfam PF01022 Bacterial regulatory protein, arsR family 45 91 5.6E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19715 979cda5a9434d868d889b6caf9128543 122 Gene3D G3DSA:1.10.10.10 82 115 1.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19715 979cda5a9434d868d889b6caf9128543 122 Gene3D G3DSA:1.10.10.10 44 81 3.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19715 979cda5a9434d868d889b6caf9128543 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 89 104 2.8E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19715 979cda5a9434d868d889b6caf9128543 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 2.8E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19715 979cda5a9434d868d889b6caf9128543 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 2.8E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19715 979cda5a9434d868d889b6caf9128543 122 SMART SM00418 38 118 1.2E-32 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS03680 90aa335f2d39938af6e2334bc7c5dbc4 145 Gene3D G3DSA:2.60.20.10 52 145 5.6E-6 T 28-03-2018 SMD44_RS03680 90aa335f2d39938af6e2334bc7c5dbc4 145 Pfam PF03995 Peptidase inhibitor family I36 51 121 2.4E-10 T 28-03-2018 SMD44_RS08745 ec4768c2f92c27fca5ba15e07d7d85e7 155 SMART SM00345 48 107 1.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08745 ec4768c2f92c27fca5ba15e07d7d85e7 155 Gene3D G3DSA:1.10.10.10 41 90 6.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08745 ec4768c2f92c27fca5ba15e07d7d85e7 155 Pfam PF00392 Bacterial regulatory proteins, gntR family 44 107 1.6E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08745 ec4768c2f92c27fca5ba15e07d7d85e7 155 Gene3D G3DSA:3.40.50.920 91 154 5.7E-4 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS08745 ec4768c2f92c27fca5ba15e07d7d85e7 155 SUPERFAMILY SSF46785 44 111 1.67E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19970 7a7f8d0541531cd4249255663943aa8b 166 SUPERFAMILY SSF46785 80 147 1.01E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19970 7a7f8d0541531cd4249255663943aa8b 166 Gene3D G3DSA:1.10.10.10 60 163 2.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19970 7a7f8d0541531cd4249255663943aa8b 166 Pfam PF12840 Helix-turn-helix domain 88 146 7.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 SUPERFAMILY SSF51735 3 170 2.02E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 38.376 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 1.9E-21 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 129 2.6E-27 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 342 6.9E-119 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 SMART SM00859 4 136 2.2E-43 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 Gene3D G3DSA:3.40.50.720 1 152 2.2E-41 T 28-03-2018 SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 SUPERFAMILY SSF55347 146 310 1.09E-48 T 28-03-2018 SMD44_RS07805 2a6e566476cfd38c1ad22b53d794085c 342 Gene3D G3DSA:3.30.360.10 153 310 9.3E-57 T 28-03-2018 SMD44_RS24370 f27fc065ed4569fae475830b364c034e 583 Pfam PF05140 ResB-like family 68 549 1.2E-131 T 28-03-2018 IPR007816 ResB-like domain SMD44_RS27470 5da9d5f89dd789bc6bf575f03fab8ca1 772 Gene3D G3DSA:1.10.3810.10 73 275 7.1E-67 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS27470 5da9d5f89dd789bc6bf575f03fab8ca1 772 Pfam PF00905 Penicillin binding protein transpeptidase domain 365 615 6.0E-38 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS27470 5da9d5f89dd789bc6bf575f03fab8ca1 772 SUPERFAMILY SSF56601 296 662 4.73E-83 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS27470 5da9d5f89dd789bc6bf575f03fab8ca1 772 SUPERFAMILY SSF56601 246 263 4.73E-83 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS27470 5da9d5f89dd789bc6bf575f03fab8ca1 772 Gene3D G3DSA:3.40.710.10 280 726 4.0E-91 T 28-03-2018 SMD44_RS27470 5da9d5f89dd789bc6bf575f03fab8ca1 772 SUPERFAMILY SSF53955 73 276 5.91E-63 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS27470 5da9d5f89dd789bc6bf575f03fab8ca1 772 Pfam PF00912 Transglycosylase 89 259 2.9E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS22145 33670d8ccc38a5da9109449d9b81b2e1 676 SUPERFAMILY SSF52540 6 224 2.19E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22145 33670d8ccc38a5da9109449d9b81b2e1 676 Pfam PF00931 NB-ARC domain 27 205 1.1E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS22145 33670d8ccc38a5da9109449d9b81b2e1 676 Gene3D G3DSA:3.40.50.300 5 144 3.2E-15 T 28-03-2018 SMD44_RS22145 33670d8ccc38a5da9109449d9b81b2e1 676 PRINTS PR00364 Disease resistance protein signature 31 46 2.7E-7 T 28-03-2018 SMD44_RS22145 33670d8ccc38a5da9109449d9b81b2e1 676 PRINTS PR00364 Disease resistance protein signature 100 114 2.7E-7 T 28-03-2018 SMD44_RS22145 33670d8ccc38a5da9109449d9b81b2e1 676 PRINTS PR00364 Disease resistance protein signature 191 205 2.7E-7 T 28-03-2018 SMD44_RS22145 33670d8ccc38a5da9109449d9b81b2e1 676 Gene3D G3DSA:1.25.40.10 325 646 5.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS11095 dd8b693cae4f134f884e08521ae24387 140 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 1.9E-28 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 SMD44_RS11095 dd8b693cae4f134f884e08521ae24387 140 Gene3D G3DSA:1.10.357.10 1 139 0.0012 T 28-03-2018 SMD44_RS28790 a2e7309fbd65bf42ca621536d4807145 350 Gene3D G3DSA:3.30.1360.70 3 116 2.9E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS28790 a2e7309fbd65bf42ca621536d4807145 350 Gene3D G3DSA:1.10.730.10 201 350 4.0E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS28790 a2e7309fbd65bf42ca621536d4807145 350 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 23 92 9.5E-16 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS28790 a2e7309fbd65bf42ca621536d4807145 350 SUPERFAMILY SSF55190 28 112 2.35E-15 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS28790 a2e7309fbd65bf42ca621536d4807145 350 SMART SM01016 4 92 1.1E-21 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD44_RS28790 a2e7309fbd65bf42ca621536d4807145 350 Pfam PF05746 DALR anticodon binding domain 235 350 5.3E-17 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMD44_RS28790 a2e7309fbd65bf42ca621536d4807145 350 SUPERFAMILY SSF47323 229 349 2.55E-18 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS28790 a2e7309fbd65bf42ca621536d4807145 350 SMART SM00836 235 350 2.1E-19 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 Pfam PF00089 Trypsin 220 372 3.9E-5 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 224 229 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 PIRSF PIRSF001134 1 398 1.6E-68 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 341 352 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 Gene3D G3DSA:3.30.300.50 36 110 8.9E-16 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 356 370 1.8E-14 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 222 236 1.8E-14 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 332 355 1.8E-14 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 SUPERFAMILY SSF50494 200 395 1.46E-25 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 Gene3D G3DSA:2.40.10.10 192 281 5.7E-12 T 28-03-2018 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 Gene3D G3DSA:2.40.10.10 282 383 2.0E-14 T 28-03-2018 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 Pfam PF02983 Alpha-lytic protease prodomain 117 171 5.0E-10 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD44_RS37245 144f78b2710a7f16874b3a5bf6058b57 398 Gene3D G3DSA:3.30.300.50 111 183 6.3E-11 T 28-03-2018 IPR035070 Streptogrisin prodomain SMD44_RS43690 adc51da924533978aa027e3641d84043 480 Gene3D G3DSA:3.40.50.300 64 443 1.0E-19 T 28-03-2018 SMD44_RS43690 adc51da924533978aa027e3641d84043 480 SUPERFAMILY SSF52540 32 300 2.32E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43690 adc51da924533978aa027e3641d84043 480 SUPERFAMILY SSF52540 339 447 2.32E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14630 09f63b671bc0a22a45428a7381b5a04e 558 Pfam PF00350 Dynamin family 65 109 2.4E-6 T 28-03-2018 IPR022812 Dynamin superfamily SMD44_RS14630 09f63b671bc0a22a45428a7381b5a04e 558 SUPERFAMILY SSF52540 151 262 3.13E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14630 09f63b671bc0a22a45428a7381b5a04e 558 SUPERFAMILY SSF52540 41 122 3.13E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14630 09f63b671bc0a22a45428a7381b5a04e 558 Gene3D G3DSA:3.40.50.300 4 469 6.1E-16 T 28-03-2018 SMD44_RS21455 b8c34b30e7b9424a743b4ed656ef3be1 487 Gene3D G3DSA:3.90.1310.10 17 141 4.3E-20 T 28-03-2018 SMD44_RS21455 b8c34b30e7b9424a743b4ed656ef3be1 487 Pfam PF00905 Penicillin binding protein transpeptidase domain 157 480 1.3E-72 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS21455 b8c34b30e7b9424a743b4ed656ef3be1 487 Gene3D G3DSA:3.40.710.10 142 487 1.0E-93 T 28-03-2018 SMD44_RS21455 b8c34b30e7b9424a743b4ed656ef3be1 487 SUPERFAMILY SSF56601 96 484 3.93E-88 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS26540 386fcb64fc85c6230354173ad7a632cd 326 Pfam PF03595 Voltage-dependent anion channel 1 291 1.4E-18 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 SMART SM00663 310 589 6.6E-174 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Gene3D G3DSA:2.40.40.20 421 563 6.7E-40 T 28-03-2018 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Gene3D G3DSA:2.40.50.100 985 1102 1.2E-40 T 28-03-2018 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 735 1.1E-21 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 468 560 9.9E-28 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 480 1.3E-8 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 8.5E-82 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1265 17.636 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 SUPERFAMILY SSF64484 5 1255 0.0 T 28-03-2018 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Pfam PF04998 RNA polymerase Rpb1, domain 5 842 1203 8.6E-67 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1255 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25465 61696f68e06df78d4e9c7b974ad44095 1303 Pfam PF05000 RNA polymerase Rpb1, domain 4 764 828 1.1E-13 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 Pfam PF00072 Response regulator receiver domain 26 116 2.2E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 2.3E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 SMART SM00421 156 213 1.0E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 SUPERFAMILY SSF52172 18 122 1.85E-11 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 SMART SM00448 19 129 0.0085 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 SUPERFAMILY SSF46894 145 219 1.46E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 Gene3D G3DSA:1.10.10.10 157 219 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32375 f9cbc38e7c0cf046d81942b76402a257 220 Gene3D G3DSA:3.40.50.2300 14 123 3.3E-10 T 28-03-2018 SMD44_RS16210 5b39615866c9cc91fe027c2ddb698a0d 394 SUPERFAMILY SSF48452 158 294 2.09E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS16210 5b39615866c9cc91fe027c2ddb698a0d 394 SUPERFAMILY SSF47413 9 51 6.95E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS16210 5b39615866c9cc91fe027c2ddb698a0d 394 Gene3D G3DSA:1.25.40.10 252 367 2.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS16210 5b39615866c9cc91fe027c2ddb698a0d 394 Gene3D G3DSA:1.25.40.10 163 251 0.0072 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS16210 5b39615866c9cc91fe027c2ddb698a0d 394 Gene3D G3DSA:1.10.260.40 2 162 2.3E-7 T 28-03-2018 SMD44_RS41895 c0ea8abdb3e6b8968218ccd1a96cfba6 112 Gene3D G3DSA:3.40.30.10 76 112 0.0012 T 28-03-2018 SMD44_RS41895 c0ea8abdb3e6b8968218ccd1a96cfba6 112 Pfam PF00085 Thioredoxin 10 111 3.8E-8 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMD44_RS41895 c0ea8abdb3e6b8968218ccd1a96cfba6 112 Gene3D G3DSA:3.40.30.10 8 75 3.8E-9 T 28-03-2018 SMD44_RS41895 c0ea8abdb3e6b8968218ccd1a96cfba6 112 SUPERFAMILY SSF52833 10 112 1.57E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS16380 92b4c661d7a1edefa174b452bd292036 319 Pfam PF01545 Cation efflux family 11 218 6.6E-35 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD44_RS16380 92b4c661d7a1edefa174b452bd292036 319 SUPERFAMILY SSF160240 222 295 1.44E-8 T 28-03-2018 SMD44_RS16380 92b4c661d7a1edefa174b452bd292036 319 Gene3D G3DSA:1.20.1510.10 6 217 2.0E-34 T 28-03-2018 SMD44_RS16380 92b4c661d7a1edefa174b452bd292036 319 Gene3D G3DSA:3.30.70.1350 218 308 3.8E-10 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMD44_RS16380 92b4c661d7a1edefa174b452bd292036 319 SUPERFAMILY SSF161111 6 219 3.53E-39 T 28-03-2018 SMD44_RS16380 92b4c661d7a1edefa174b452bd292036 319 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 288 3.0E-42 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 12 960 25.759 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 Gene3D G3DSA:3.90.1150.10 350 450 1.0E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 SUPERFAMILY SSF53383 933 956 2.78E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 SUPERFAMILY SSF53383 480 891 2.78E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 Pfam PF02347 Glycine cleavage system P-protein 20 448 5.1E-181 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 Pfam PF02347 Glycine cleavage system P-protein 456 737 5.5E-12 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 Gene3D G3DSA:3.40.640.10 100 349 3.3E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 Gene3D G3DSA:3.90.1150.10 777 909 2.3E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 SUPERFAMILY SSF53383 21 448 2.59E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 21 954 0.0 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMD44_RS06590 7781195cd4f4c58625acbdf2260179c0 962 Gene3D G3DSA:3.40.640.10 534 776 1.0E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS36220 e5630032acb0b799c05ec33958a6702e 343 SUPERFAMILY SSF53901 10 337 8.66E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36220 e5630032acb0b799c05ec33958a6702e 343 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 15 337 8.1E-100 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS36220 e5630032acb0b799c05ec33958a6702e 343 Gene3D G3DSA:3.40.47.10 13 169 5.8E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36220 e5630032acb0b799c05ec33958a6702e 343 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 196 3.2E-29 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS36220 e5630032acb0b799c05ec33958a6702e 343 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 13 337 64.804 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS36220 e5630032acb0b799c05ec33958a6702e 343 Gene3D G3DSA:3.40.47.10 170 339 8.4E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36220 e5630032acb0b799c05ec33958a6702e 343 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 248 337 9.3E-33 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS17045 48b0573ac4a0b7d913527a9014daa74d 597 Gene3D G3DSA:2.140.10.10 155 376 2.6E-11 T 28-03-2018 SMD44_RS17045 48b0573ac4a0b7d913527a9014daa74d 597 Gene3D G3DSA:2.140.10.10 377 589 7.4E-11 T 28-03-2018 SMD44_RS17045 48b0573ac4a0b7d913527a9014daa74d 597 Pfam PF13360 PQQ-like domain 203 348 4.8E-8 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS17045 48b0573ac4a0b7d913527a9014daa74d 597 SUPERFAMILY SSF50998 469 509 6.02E-12 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS17045 48b0573ac4a0b7d913527a9014daa74d 597 SUPERFAMILY SSF50998 197 408 6.02E-12 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS27765 3e1231d4a426f1a88577acf92fe55014 324 SMART SM00382 47 223 1.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS27765 3e1231d4a426f1a88577acf92fe55014 324 Gene3D G3DSA:3.40.50.300 20 276 1.8E-61 T 28-03-2018 SMD44_RS27765 3e1231d4a426f1a88577acf92fe55014 324 Pfam PF00005 ABC transporter 39 174 6.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS27765 3e1231d4a426f1a88577acf92fe55014 324 SUPERFAMILY SSF52540 23 238 3.07E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11820 2118b9f141dd28e6d7a68eb7da928c24 304 Pfam PF10118 Predicted metal-dependent hydrolase 20 277 1.7E-79 T 28-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 SMD44_RS11820 2118b9f141dd28e6d7a68eb7da928c24 304 PIRSF PIRSF007580 5 297 3.7E-125 T 28-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 SMD44_RS11820 2118b9f141dd28e6d7a68eb7da928c24 304 Gene3D G3DSA:1.20.1260.10 42 264 8.6E-10 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS28660 274a4dda83af671dab09f8577103d143 181 Gene3D G3DSA:3.30.450.30 34 174 2.1E-46 T 28-03-2018 SMD44_RS28660 274a4dda83af671dab09f8577103d143 181 SUPERFAMILY SSF103196 33 170 2.79E-19 T 28-03-2018 SMD44_RS28660 274a4dda83af671dab09f8577103d143 181 Pfam PF03259 Roadblock/LC7 domain 88 140 7.4E-7 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS28660 274a4dda83af671dab09f8577103d143 181 SMART SM00960 39 142 2.9E-15 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS11045 0498ebcfc661809a1fdd073077e1e4b2 356 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 7.9E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS11045 0498ebcfc661809a1fdd073077e1e4b2 356 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 349 24.056 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS11045 0498ebcfc661809a1fdd073077e1e4b2 356 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS11045 0498ebcfc661809a1fdd073077e1e4b2 356 Pfam PF00953 Glycosyl transferase family 4 82 275 2.8E-37 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SMD44_RS11045 0498ebcfc661809a1fdd073077e1e4b2 356 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 19 345 1.6E-99 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS11045 0498ebcfc661809a1fdd073077e1e4b2 356 ProSitePatterns PS01348 MraY family signature 2. 174 185 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS19085 358059ca3cca52c4a81d7c9e5f4adeb1 354 SUPERFAMILY SSF54001 241 342 7.85E-33 T 28-03-2018 SMD44_RS19085 358059ca3cca52c4a81d7c9e5f4adeb1 354 Gene3D G3DSA:1.20.120.330 39 224 3.5E-4 T 28-03-2018 SMD44_RS19085 358059ca3cca52c4a81d7c9e5f4adeb1 354 Gene3D G3DSA:3.90.1720.10 229 343 4.0E-34 T 28-03-2018 SMD44_RS19085 358059ca3cca52c4a81d7c9e5f4adeb1 354 Pfam PF00877 NlpC/P60 family 253 335 1.3E-19 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 2.1E-35 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 2.1E-35 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 185 197 2.1E-35 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 2.1E-35 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 2.1E-35 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 2.1E-35 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 Pfam PF02056 Family 4 glycosyl hydrolase 2 178 2.3E-46 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 397 2.6E-40 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 Gene3D G3DSA:3.40.50.720 1 154 3.5E-30 T 28-03-2018 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 Gene3D G3DSA:3.90.110.10 155 421 3.9E-97 T 28-03-2018 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 SUPERFAMILY SSF56327 165 418 2.42E-63 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD44_RS14475 acac4298900fa2ef2e0afa72f85a9464 421 SUPERFAMILY SSF51735 1 156 7.89E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS39240 60ef334547d094c156c8df8881f33995 248 Pfam PF04055 Radical SAM superfamily 31 180 1.3E-25 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS39240 60ef334547d094c156c8df8881f33995 248 Pfam PF13353 4Fe-4S single cluster domain 21 115 3.5E-17 T 28-03-2018 SMD44_RS39240 60ef334547d094c156c8df8881f33995 248 PIRSF PIRSF000371 2 53 9.0E-11 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 SMD44_RS39240 60ef334547d094c156c8df8881f33995 248 PIRSF PIRSF000371 49 241 1.0E-39 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 SMD44_RS39240 60ef334547d094c156c8df8881f33995 248 Gene3D G3DSA:3.20.20.70 17 243 6.6E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS39240 60ef334547d094c156c8df8881f33995 248 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 11 241 6.5E-90 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 SMD44_RS39240 60ef334547d094c156c8df8881f33995 248 ProSitePatterns PS01087 Radical activating enzymes signature. 23 44 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 SMD44_RS39240 60ef334547d094c156c8df8881f33995 248 SUPERFAMILY SSF102114 28 219 2.09E-26 T 28-03-2018 SMD44_RS11975 3e50aa367edb6519913f2523ed80d8d9 354 Pfam PF00005 ABC transporter 44 187 3.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS11975 3e50aa367edb6519913f2523ed80d8d9 354 Pfam PF13732 Domain of unknown function (DUF4162) 241 333 3.8E-7 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 SMD44_RS11975 3e50aa367edb6519913f2523ed80d8d9 354 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 36 335 3.9E-119 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD44_RS11975 3e50aa367edb6519913f2523ed80d8d9 354 Gene3D G3DSA:3.40.50.300 26 284 8.1E-63 T 28-03-2018 SMD44_RS11975 3e50aa367edb6519913f2523ed80d8d9 354 SUPERFAMILY SSF52540 29 250 5.97E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11975 3e50aa367edb6519913f2523ed80d8d9 354 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS11975 3e50aa367edb6519913f2523ed80d8d9 354 SMART SM00382 53 236 4.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS15855 b5b7e6662d2f48b74656d0bde36fa769 183 Pfam PF00857 Isochorismatase family 10 141 5.9E-33 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS15855 b5b7e6662d2f48b74656d0bde36fa769 183 Gene3D G3DSA:3.40.50.850 4 165 3.2E-37 T 28-03-2018 SMD44_RS15855 b5b7e6662d2f48b74656d0bde36fa769 183 SUPERFAMILY SSF52499 3 144 3.01E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS33980 d42689542c2a6348ce2378450fbd82cc 216 Gene3D G3DSA:1.20.1250.20 3 188 4.2E-23 T 28-03-2018 SMD44_RS33980 d42689542c2a6348ce2378450fbd82cc 216 Pfam PF07690 Major Facilitator Superfamily 8 190 1.7E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS33980 d42689542c2a6348ce2378450fbd82cc 216 SUPERFAMILY SSF103473 3 188 7.85E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS30580 9e915b0b4406b7d2a5ecbf17d59db8b5 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.9E-60 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SMD44_RS30580 9e915b0b4406b7d2a5ecbf17d59db8b5 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.307 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SMD44_RS30580 9e915b0b4406b7d2a5ecbf17d59db8b5 185 Gene3D G3DSA:1.10.132.20 2 73 9.5E-10 T 28-03-2018 SMD44_RS30580 9e915b0b4406b7d2a5ecbf17d59db8b5 185 Gene3D G3DSA:1.10.132.20 74 184 2.9E-35 T 28-03-2018 SMD44_RS30580 9e915b0b4406b7d2a5ecbf17d59db8b5 185 Pfam PF01765 Ribosome recycling factor 21 183 1.5E-57 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SMD44_RS30580 9e915b0b4406b7d2a5ecbf17d59db8b5 185 SUPERFAMILY SSF55194 3 184 4.32E-65 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SMD44_RS00380 1bf550a9ad593d4da5d2e81ca27de378 181 SUPERFAMILY SSF101874 12 178 3.01E-40 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS00380 1bf550a9ad593d4da5d2e81ca27de378 181 SMART SM00867 13 177 3.1E-38 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS00380 1bf550a9ad593d4da5d2e81ca27de378 181 Gene3D G3DSA:2.40.128.110 9 180 8.9E-40 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS00380 1bf550a9ad593d4da5d2e81ca27de378 181 Pfam PF04264 YceI-like domain 14 175 4.2E-33 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS36420 0d1fcb1c5bb7126cfc72fd93ad572fda 508 Gene3D G3DSA:3.40.50.980 169 324 3.7E-35 T 28-03-2018 SMD44_RS36420 0d1fcb1c5bb7126cfc72fd93ad572fda 508 Gene3D G3DSA:2.30.38.10 329 396 5.8E-15 T 28-03-2018 SMD44_RS36420 0d1fcb1c5bb7126cfc72fd93ad572fda 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 489 4.9E-25 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS36420 0d1fcb1c5bb7126cfc72fd93ad572fda 508 Pfam PF00501 AMP-binding enzyme 18 402 5.9E-80 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS36420 0d1fcb1c5bb7126cfc72fd93ad572fda 508 Gene3D G3DSA:3.40.50.980 4 168 4.5E-38 T 28-03-2018 SMD44_RS36420 0d1fcb1c5bb7126cfc72fd93ad572fda 508 SUPERFAMILY SSF56801 4 500 4.45E-131 T 28-03-2018 SMD44_RS36420 0d1fcb1c5bb7126cfc72fd93ad572fda 508 Gene3D G3DSA:3.30.300.30 397 508 1.0E-31 T 28-03-2018 SMD44_RS29650 6b723e5902e403c52fcd8dc25b1ea4af 456 Pfam PF03315 Serine dehydratase beta chain 4 157 1.6E-59 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SMD44_RS29650 6b723e5902e403c52fcd8dc25b1ea4af 456 Gene3D G3DSA:3.30.1330.90 11 160 5.4E-58 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMD44_RS29650 6b723e5902e403c52fcd8dc25b1ea4af 456 SUPERFAMILY SSF143548 17 158 8.37E-48 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMD44_RS29650 6b723e5902e403c52fcd8dc25b1ea4af 456 Pfam PF03313 Serine dehydratase alpha chain 189 450 6.7E-105 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit SMD44_RS29650 6b723e5902e403c52fcd8dc25b1ea4af 456 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 453 1.2E-211 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SMD44_RS29650 6b723e5902e403c52fcd8dc25b1ea4af 456 Gene3D G3DSA:1.10.4100.10 236 444 2.6E-36 T 28-03-2018 SMD44_RS05395 f91f4f42e485a5c0943c97fc5fa62fca 313 Gene3D G3DSA:3.40.50.1820 5 305 1.5E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05395 f91f4f42e485a5c0943c97fc5fa62fca 313 Pfam PF12740 Chlorophyllase enzyme 37 151 2.3E-8 T 28-03-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 SMD44_RS05395 f91f4f42e485a5c0943c97fc5fa62fca 313 SUPERFAMILY SSF53474 15 253 4.46E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28210 8d075b50c73ae4f215edb34a3d4ceb85 139 SUPERFAMILY SSF46785 3 134 4.9E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28210 8d075b50c73ae4f215edb34a3d4ceb85 139 Gene3D G3DSA:1.10.10.10 1 83 8.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28210 8d075b50c73ae4f215edb34a3d4ceb85 139 Pfam PF01475 Ferric uptake regulator family 11 103 1.3E-24 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMD44_RS43765 98e754ec9f2d4981036474f95499805f 189 SUPERFAMILY SSF52540 2 111 8.63E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43765 98e754ec9f2d4981036474f95499805f 189 Gene3D G3DSA:3.40.50.300 1 183 1.6E-7 T 28-03-2018 SMD44_RS43765 98e754ec9f2d4981036474f95499805f 189 Pfam PF13521 AAA domain 1 166 1.3E-12 T 28-03-2018 SMD44_RS17580 6d532decfcd78003061413bd2fbbd952 183 SUPERFAMILY SSF51161 41 182 1.8E-42 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS17580 6d532decfcd78003061413bd2fbbd952 183 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 129 163 8.1E-9 T 28-03-2018 IPR001451 Hexapeptide repeat SMD44_RS17580 6d532decfcd78003061413bd2fbbd952 183 Gene3D G3DSA:2.160.10.10 2 183 6.6E-41 T 28-03-2018 SMD44_RS17580 6d532decfcd78003061413bd2fbbd952 183 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SMD44_RS37700 f6f819fe041964ae1fdfadc02d3658d1 137 Gene3D G3DSA:1.10.10.10 14 134 5.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37700 f6f819fe041964ae1fdfadc02d3658d1 137 SUPERFAMILY SSF46785 19 127 2.33E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37700 f6f819fe041964ae1fdfadc02d3658d1 137 Pfam PF01638 HxlR-like helix-turn-helix 33 123 4.5E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS10645 d6d7ce2aef584f82a6b187bdc29ee07e 483 SMART SM00490 292 373 1.2E-26 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS10645 d6d7ce2aef584f82a6b187bdc29ee07e 483 Pfam PF00271 Helicase conserved C-terminal domain 275 373 2.0E-23 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS10645 d6d7ce2aef584f82a6b187bdc29ee07e 483 SMART SM00487 57 257 8.2E-49 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS10645 d6d7ce2aef584f82a6b187bdc29ee07e 483 Gene3D G3DSA:3.40.50.300 40 258 1.9E-50 T 28-03-2018 SMD44_RS10645 d6d7ce2aef584f82a6b187bdc29ee07e 483 Pfam PF00270 DEAD/DEAH box helicase 62 231 7.7E-44 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS10645 d6d7ce2aef584f82a6b187bdc29ee07e 483 Gene3D G3DSA:3.40.50.300 259 483 6.2E-37 T 28-03-2018 SMD44_RS10645 d6d7ce2aef584f82a6b187bdc29ee07e 483 SUPERFAMILY SSF52540 109 392 1.45E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34310 256dd91337c7d4b5a61682c03ba6ec33 652 SUPERFAMILY SSF48452 467 537 2.53E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34310 256dd91337c7d4b5a61682c03ba6ec33 652 Pfam PF17128 Domain of unknown function (DUF5107) 59 337 8.4E-37 T 28-03-2018 IPR033396 Domain of unknown function DUF5107 SMD44_RS34310 256dd91337c7d4b5a61682c03ba6ec33 652 Gene3D G3DSA:1.25.40.10 459 643 1.4E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34310 256dd91337c7d4b5a61682c03ba6ec33 652 Gene3D G3DSA:3.40.190.10 284 408 0.0031 T 28-03-2018 SMD44_RS34310 256dd91337c7d4b5a61682c03ba6ec33 652 Gene3D G3DSA:2.70.98.10 62 139 1.3E-5 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMD44_RS19375 e13278561d70593776425bdc94fe7007 368 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 52 365 2.9E-76 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SMD44_RS19375 e13278561d70593776425bdc94fe7007 368 SUPERFAMILY SSF53850 51 367 1.75E-85 T 28-03-2018 SMD44_RS19375 e13278561d70593776425bdc94fe7007 368 Pfam PF12849 PBP superfamily domain 46 338 2.0E-58 T 28-03-2018 IPR024370 PBP domain SMD44_RS19375 e13278561d70593776425bdc94fe7007 368 Gene3D G3DSA:3.40.190.10 188 366 3.3E-27 T 28-03-2018 SMD44_RS19375 e13278561d70593776425bdc94fe7007 368 PIRSF PIRSF002756 5 368 2.2E-118 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SMD44_RS19375 e13278561d70593776425bdc94fe7007 368 Gene3D G3DSA:3.40.190.10 48 187 1.3E-26 T 28-03-2018 SMD44_RS07280 1badb13d8dae49cc6119bf0a82d3fa22 191 SUPERFAMILY SSF53271 11 176 2.23E-41 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS07280 1badb13d8dae49cc6119bf0a82d3fa22 191 Pfam PF00156 Phosphoribosyl transferase domain 12 152 2.0E-20 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD44_RS07280 1badb13d8dae49cc6119bf0a82d3fa22 191 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 9 182 37.325 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SMD44_RS07280 1badb13d8dae49cc6119bf0a82d3fa22 191 Gene3D G3DSA:3.40.50.2020 5 185 1.2E-36 T 28-03-2018 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 Gene3D G3DSA:1.10.540.10 1 117 3.3E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 402 1.6E-52 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 Gene3D G3DSA:2.40.110.10 125 222 1.7E-33 T 28-03-2018 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 Gene3D G3DSA:1.20.140.10 223 408 1.4E-57 T 28-03-2018 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 361 380 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 1.5E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 115 1.8E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 SUPERFAMILY SSF47203 258 406 3.87E-54 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS05580 8062940c8c9e4e47e62d7483976e4a79 408 SUPERFAMILY SSF56645 5 234 3.01E-58 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS13070 5341ae26ad7fe86c9418c0962bb26241 332 SUPERFAMILY SSF53686 2 269 7.68E-40 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS13070 5341ae26ad7fe86c9418c0962bb26241 332 Gene3D G3DSA:3.40.50.1100 1 100 8.2E-15 T 28-03-2018 SMD44_RS13070 5341ae26ad7fe86c9418c0962bb26241 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 2 256 1.1E-27 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS13070 5341ae26ad7fe86c9418c0962bb26241 332 Gene3D G3DSA:3.40.50.1100 101 272 1.1E-22 T 28-03-2018 SMD44_RS20285 63091fa54e089f2bff9eef4c19bb2dab 272 Pfam PF04264 YceI-like domain 97 263 5.9E-38 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS20285 63091fa54e089f2bff9eef4c19bb2dab 272 SUPERFAMILY SSF101874 95 266 2.22E-51 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS20285 63091fa54e089f2bff9eef4c19bb2dab 272 Gene3D G3DSA:2.40.128.110 100 270 1.2E-53 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS20285 63091fa54e089f2bff9eef4c19bb2dab 272 SMART SM00867 96 264 1.3E-62 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS20285 63091fa54e089f2bff9eef4c19bb2dab 272 SUPERFAMILY SSF49452 3 79 7.85E-6 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 SMD44_RS20285 63091fa54e089f2bff9eef4c19bb2dab 272 Gene3D G3DSA:2.60.40.1120 2 99 7.5E-8 T 28-03-2018 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 Gene3D G3DSA:1.25.40.10 45 134 1.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 Gene3D G3DSA:1.25.40.10 183 234 5.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 Gene3D G3DSA:1.25.40.10 135 182 2.9E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 SUPERFAMILY SSF48452 98 319 1.29E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 Gene3D G3DSA:1.25.40.10 336 465 2.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 SMART SM00028 254 287 59.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 SMART SM00028 288 321 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 SMART SM00028 150 183 320.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 SMART SM00028 426 459 68.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 SMART SM00028 116 149 18.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 Gene3D G3DSA:1.25.40.10 235 335 4.0E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 Pfam PF13432 Tetratricopeptide repeat 259 319 7.2E-5 T 28-03-2018 SMD44_RS08685 bc934efa8e49ad39d6039b6c908dfcb5 475 SUPERFAMILY SSF48452 262 459 3.03E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 SUPERFAMILY SSF116726 133 216 7.59E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 Pfam PF02080 TrkA-C domain 149 216 8.2E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 Gene3D G3DSA:3.40.50.720 1 145 4.3E-25 T 28-03-2018 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 Pfam PF02254 TrkA-N domain 3 118 2.9E-24 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.3E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 3.3E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 3.3E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.3E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 Gene3D G3DSA:3.30.70.1450 146 221 3.6E-17 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS31910 84a96e73c0847c9b5d9ebad56e659472 222 SUPERFAMILY SSF51735 1 145 3.38E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09775 a80fbb5e385d0fdc7067c02fac317b9f 481 SUPERFAMILY SSF56601 137 480 4.54E-89 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS09775 a80fbb5e385d0fdc7067c02fac317b9f 481 Pfam PF00905 Penicillin binding protein transpeptidase domain 154 476 6.1E-65 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS09775 a80fbb5e385d0fdc7067c02fac317b9f 481 Gene3D G3DSA:3.40.710.10 138 481 1.1E-87 T 28-03-2018 SMD44_RS09775 a80fbb5e385d0fdc7067c02fac317b9f 481 Gene3D G3DSA:3.90.1310.10 17 137 1.2E-14 T 28-03-2018 SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 Pfam PF05922 Peptidase inhibitor I9 72 117 2.8E-8 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 Gene3D G3DSA:3.30.70.80 43 121 4.2E-15 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 Pfam PF00082 Subtilase family 150 379 2.0E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 Gene3D G3DSA:3.40.50.200 122 397 1.8E-75 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 342 352 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 SUPERFAMILY SSF52743 122 387 4.71E-72 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 341 357 3.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 150 169 3.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 188 201 3.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 155 166 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS29450 cdd467a7cfdd0f693bb2d290ebcdd2bc 399 SUPERFAMILY SSF54897 50 117 2.38E-7 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 SMD44_RS39405 2d5824c0d2cb4bf6c76ef278a63bc4e2 300 SUPERFAMILY SSF54637 117 287 4.69E-48 T 28-03-2018 IPR029069 HotDog domain SMD44_RS39405 2d5824c0d2cb4bf6c76ef278a63bc4e2 300 Gene3D G3DSA:3.10.129.10 2 116 1.1E-45 T 28-03-2018 SMD44_RS39405 2d5824c0d2cb4bf6c76ef278a63bc4e2 300 Pfam PF13622 Thioesterase-like superfamily 33 284 3.3E-62 T 28-03-2018 SMD44_RS39405 2d5824c0d2cb4bf6c76ef278a63bc4e2 300 Gene3D G3DSA:3.10.129.10 134 289 1.2E-50 T 28-03-2018 SMD44_RS39405 2d5824c0d2cb4bf6c76ef278a63bc4e2 300 SUPERFAMILY SSF54637 6 114 2.24E-42 T 28-03-2018 IPR029069 HotDog domain SMD44_RS11860 51174bc45899cd81dc80af610335caa6 170 Gene3D G3DSA:2.30.110.10 2 160 5.7E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS11860 51174bc45899cd81dc80af610335caa6 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 25 109 1.3E-15 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS11860 51174bc45899cd81dc80af610335caa6 170 SUPERFAMILY SSF50475 22 167 6.39E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 SUPERFAMILY SSF46894 867 929 6.8E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 Gene3D G3DSA:3.40.50.300 2 225 1.4E-10 T 28-03-2018 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 Gene3D G3DSA:1.25.40.10 686 885 2.6E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 Gene3D G3DSA:1.25.40.10 523 685 0.0063 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 889 2.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 905 917 2.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 889 905 2.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 Gene3D G3DSA:1.10.10.10 886 932 6.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 Pfam PF13191 AAA ATPase domain 2 173 6.7E-21 T 28-03-2018 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 SUPERFAMILY SSF52540 4 65 1.77E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 SUPERFAMILY SSF52540 110 240 1.77E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 SMART SM00421 872 929 2.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 Pfam PF00196 Bacterial regulatory proteins, luxR family 874 925 2.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS08660 9c83e385bb3e28e831f8532892f85cb4 933 ProSitePatterns PS00622 LuxR-type HTH domain signature. 889 916 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 Gene3D G3DSA:1.10.1660.10 10 69 6.7E-22 T 28-03-2018 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 Gene3D G3DSA:1.10.1660.10 70 138 2.1E-6 T 28-03-2018 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 Pfam PF08241 Methyltransferase domain 171 249 3.2E-11 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 Gene3D G3DSA:3.40.50.150 139 380 7.0E-25 T 28-03-2018 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 SMART SM00422 14 83 2.0E-29 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 SUPERFAMILY SSF53335 144 296 2.44E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 26 1.3E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 50 70 1.3E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 26 39 1.3E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 Pfam PF00376 MerR family regulatory protein 15 52 1.2E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 SUPERFAMILY SSF46955 14 117 3.66E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS37900 125dff240f0cc1c28194ebd74259f893 380 ProSitePatterns PS00552 MerR-type HTH domain signature. 17 39 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS05755 a2e92c3aa84aaf8b7184e4ac77e39a06 100 SUPERFAMILY SSF54111 2 99 5.23E-46 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05755 a2e92c3aa84aaf8b7184e4ac77e39a06 100 PIRSF PIRSF001223 1 100 3.7E-52 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05755 a2e92c3aa84aaf8b7184e4ac77e39a06 100 Gene3D G3DSA:3.30.280.10 2 99 5.9E-49 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05755 a2e92c3aa84aaf8b7184e4ac77e39a06 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 3.4E-50 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05755 a2e92c3aa84aaf8b7184e4ac77e39a06 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-43 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05755 a2e92c3aa84aaf8b7184e4ac77e39a06 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.811 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05755 a2e92c3aa84aaf8b7184e4ac77e39a06 100 Pfam PF00547 Urease, gamma subunit 2 99 2.5E-47 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS18260 376027f3d4304145301c3231193f15b5 249 Gene3D G3DSA:3.90.226.10 2 248 6.2E-57 T 28-03-2018 SMD44_RS18260 376027f3d4304145301c3231193f15b5 249 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 247 1.3E-41 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS18260 376027f3d4304145301c3231193f15b5 249 SUPERFAMILY SSF52096 7 247 5.22E-56 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 285 318 0.0021 T 28-03-2018 IPR001451 Hexapeptide repeat SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 SUPERFAMILY SSF53738 637 741 5.49E-11 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 384 511 2.3E-13 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 639 740 2.0E-4 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Gene3D G3DSA:3.30.310.50 740 830 2.2E-4 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 532 632 1.9E-16 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 SUPERFAMILY SSF53448 269 325 1.52E-81 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 SUPERFAMILY SSF53448 1 237 1.52E-81 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 SUPERFAMILY SSF55957 744 828 3.4E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 SUPERFAMILY SSF53738 530 634 4.71E-14 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Gene3D G3DSA:3.90.550.10 1 234 1.4E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Gene3D G3DSA:3.40.120.10 529 639 1.7E-15 T 28-03-2018 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Pfam PF00483 Nucleotidyl transferase 2 233 2.6E-54 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 SUPERFAMILY SSF51161 244 433 2.57E-33 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Gene3D G3DSA:3.40.120.10 381 524 8.7E-14 T 28-03-2018 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Gene3D G3DSA:2.160.10.10 313 378 4.7E-12 T 28-03-2018 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Gene3D G3DSA:3.40.120.10 640 739 6.2E-11 T 28-03-2018 SMD44_RS06640 2af6a68318ad8227f9a6d90684037f7a 831 Gene3D G3DSA:2.160.10.10 235 312 1.3E-15 T 28-03-2018 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 SUPERFAMILY SSF52374 16 179 4.07E-32 T 28-03-2018 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 Pfam PF01687 Riboflavin kinase 188 309 3.3E-32 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 Pfam PF06574 FAD synthetase 12 156 6.5E-50 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 SUPERFAMILY SSF82114 178 312 6.54E-42 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 Gene3D G3DSA:2.40.30.30 184 315 5.3E-42 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 SMART SM00904 187 312 1.0E-49 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 PIRSF PIRSF004491 1 316 2.6E-96 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 309 3.9E-66 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SMD44_RS30900 618c3999f4d23b80a0427c5aef3cd65e 319 Gene3D G3DSA:3.40.50.620 1 183 9.3E-49 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS17595 b3eb18a83619dda394fb6286a37e3297 306 Gene3D G3DSA:1.10.1660.10 27 145 9.1E-18 T 28-03-2018 SMD44_RS17595 b3eb18a83619dda394fb6286a37e3297 306 SUPERFAMILY SSF46955 30 134 5.49E-21 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS17595 b3eb18a83619dda394fb6286a37e3297 306 ProSitePatterns PS00552 MerR-type HTH domain signature. 32 54 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17595 b3eb18a83619dda394fb6286a37e3297 306 Pfam PF13411 MerR HTH family regulatory protein 30 96 8.0E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17595 b3eb18a83619dda394fb6286a37e3297 306 Gene3D G3DSA:3.20.80.10 146 306 7.9E-19 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain SMD44_RS17595 b3eb18a83619dda394fb6286a37e3297 306 SMART SM00422 29 99 1.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS21635 82fa914fae61feb4c5cbf703a7b845b9 236 SUPERFAMILY SSF52540 1 216 1.16E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21635 82fa914fae61feb4c5cbf703a7b845b9 236 SMART SM00382 25 204 1.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS21635 82fa914fae61feb4c5cbf703a7b845b9 236 Gene3D G3DSA:3.40.50.300 1 235 7.0E-57 T 28-03-2018 SMD44_RS21635 82fa914fae61feb4c5cbf703a7b845b9 236 Pfam PF00005 ABC transporter 17 155 7.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS21635 82fa914fae61feb4c5cbf703a7b845b9 236 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS40980 593825dcca398ca59d43a62b7b55ce7d 74 SUPERFAMILY SSF47336 2 70 7.07E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS40980 593825dcca398ca59d43a62b7b55ce7d 74 Gene3D G3DSA:1.10.1200.10 1 72 5.7E-17 T 28-03-2018 SMD44_RS40980 593825dcca398ca59d43a62b7b55ce7d 74 Pfam PF00550 Phosphopantetheine attachment site 4 70 4.4E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS40980 593825dcca398ca59d43a62b7b55ce7d 74 SMART SM00823 Phosphopantetheine attachment site 3 61 5.4E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 Gene3D G3DSA:3.40.50.720 2 290 1.5E-50 T 28-03-2018 SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 Pfam PF00106 short chain dehydrogenase 7 193 4.1E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 SUPERFAMILY SSF51735 5 207 1.01E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 SUPERFAMILY SSF51735 235 263 1.01E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 6.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 6.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09470 974b23950de7d9cebac47cd44ef9d89d 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07995 4cec483ba395a1786ce8ce96b6161365 250 Gene3D G3DSA:3.40.50.880 20 249 3.6E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS07995 4cec483ba395a1786ce8ce96b6161365 250 Pfam PF07722 Peptidase C26 24 231 1.9E-65 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 SMD44_RS07995 4cec483ba395a1786ce8ce96b6161365 250 SUPERFAMILY SSF52317 51 245 2.37E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 PRINTS PR00718 Phospholipase D signature 47 70 4.5E-5 T 28-03-2018 IPR001028 Glycoprotein phospholipase D GO:0004621|GO:0005576 KEGG: 00563+3.1.4.50|Reactome: R-HSA-163125 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 PRINTS PR00718 Phospholipase D signature 486 501 4.5E-5 T 28-03-2018 IPR001028 Glycoprotein phospholipase D GO:0004621|GO:0005576 KEGG: 00563+3.1.4.50|Reactome: R-HSA-163125 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 Gene3D G3DSA:2.130.10.130 419 500 9.9E-9 T 28-03-2018 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 Gene3D G3DSA:2.60.40.680 21 139 4.3E-18 T 28-03-2018 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 SUPERFAMILY SSF69318 47 457 1.64E-56 T 28-03-2018 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 Pfam PF01839 FG-GAP repeat 166 187 4.0E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 Pfam PF01839 FG-GAP repeat 363 399 2.3E-7 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 Gene3D G3DSA:2.130.10.130 299 418 1.1E-17 T 28-03-2018 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 Gene3D G3DSA:2.130.10.130 146 298 2.5E-12 T 28-03-2018 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 51 132 2.8E-7 T 28-03-2018 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 SMART SM00191 109 165 160.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 SMART SM00191 40 97 0.14 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 SMART SM00191 359 417 6.9E-7 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 SMART SM00191 294 350 11.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS38505 482c60198aded719a4c308436c7b7814 501 SMART SM00191 429 483 0.025 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS03180 a7d3d4412bf4b052aa31354a5f0faf47 144 SUPERFAMILY SSF54427 16 141 7.74E-27 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS03180 a7d3d4412bf4b052aa31354a5f0faf47 144 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 16 138 1.1E-16 T 28-03-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 SMD44_RS03180 a7d3d4412bf4b052aa31354a5f0faf47 144 Gene3D G3DSA:3.10.450.50 12 144 1.6E-15 T 28-03-2018 SMD44_RS03180 a7d3d4412bf4b052aa31354a5f0faf47 144 Pfam PF14534 Domain of unknown function (DUF4440) 19 130 1.2E-7 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 SMD44_RS22235 77a7777ae1767c637373fd252190681c 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 87 1.5E-7 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS22235 77a7777ae1767c637373fd252190681c 142 SUPERFAMILY SSF50475 1 139 1.7E-22 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS22235 77a7777ae1767c637373fd252190681c 142 Gene3D G3DSA:2.30.110.10 2 141 4.7E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS11060 e6cd1e418a0e7020bd3c5a4a85ce1863 672 Gene3D G3DSA:3.90.1310.10 77 291 1.4E-36 T 28-03-2018 SMD44_RS11060 e6cd1e418a0e7020bd3c5a4a85ce1863 672 Gene3D G3DSA:3.40.710.10 292 643 5.1E-90 T 28-03-2018 SMD44_RS11060 e6cd1e418a0e7020bd3c5a4a85ce1863 672 SUPERFAMILY SSF56601 295 652 2.22E-87 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS11060 e6cd1e418a0e7020bd3c5a4a85ce1863 672 Pfam PF03717 Penicillin-binding Protein dimerisation domain 109 274 2.0E-11 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMD44_RS11060 e6cd1e418a0e7020bd3c5a4a85ce1863 672 SUPERFAMILY SSF56519 105 294 8.76E-32 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMD44_RS11060 e6cd1e418a0e7020bd3c5a4a85ce1863 672 Pfam PF00905 Penicillin binding protein transpeptidase domain 320 635 8.3E-79 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS32750 6b4939cbf6d1518b355c018c0acef5f7 413 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 289 330 - T 28-03-2018 IPR035595 UDP-glycosyltransferase family, conserved site Reactome: R-HSA-156588 SMD44_RS32750 6b4939cbf6d1518b355c018c0acef5f7 413 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 226 367 6.3E-14 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 SMD44_RS32750 6b4939cbf6d1518b355c018c0acef5f7 413 Gene3D G3DSA:3.40.50.2000 229 382 4.2E-37 T 28-03-2018 SMD44_RS32750 6b4939cbf6d1518b355c018c0acef5f7 413 SUPERFAMILY SSF53756 8 395 5.83E-77 T 28-03-2018 SMD44_RS32750 6b4939cbf6d1518b355c018c0acef5f7 413 Gene3D G3DSA:3.40.50.2000 1 228 2.6E-36 T 28-03-2018 SMD44_RS32750 6b4939cbf6d1518b355c018c0acef5f7 413 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 12 396 2.1E-141 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 SMD44_RS30485 dfaccd4f92103a6627c1688b963060fc 193 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 166 22.789 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SMD44_RS30485 dfaccd4f92103a6627c1688b963060fc 193 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 166 5.6E-42 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SMD44_RS30485 dfaccd4f92103a6627c1688b963060fc 193 Gene3D G3DSA:2.40.30.60 2 91 2.7E-25 T 28-03-2018 IPR002676 RimM protein GO:0006364 SMD44_RS30485 dfaccd4f92103a6627c1688b963060fc 193 SUPERFAMILY SSF50447 3 85 2.08E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS30485 dfaccd4f92103a6627c1688b963060fc 193 Pfam PF01782 RimM N-terminal domain 5 83 1.8E-21 T 28-03-2018 IPR002676 RimM protein GO:0006364 SMD44_RS30485 dfaccd4f92103a6627c1688b963060fc 193 Gene3D G3DSA:2.30.30.240 92 161 2.5E-21 T 28-03-2018 SMD44_RS30485 dfaccd4f92103a6627c1688b963060fc 193 SUPERFAMILY SSF50346 96 166 9.61E-18 T 28-03-2018 IPR011033 PRC-barrel-like SMD44_RS30485 dfaccd4f92103a6627c1688b963060fc 193 Pfam PF05239 PRC-barrel domain 94 166 1.8E-8 T 28-03-2018 IPR027275 PRC-barrel domain SMD44_RS40220 f369b8471916524baf0cdfc1863dec9a 521 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 51 146 3.1E-28 T 28-03-2018 IPR032093 Phospholipase D, N-terminal SMD44_RS40220 f369b8471916524baf0cdfc1863dec9a 521 Pfam PF09423 PhoD-like phosphatase 157 475 2.0E-89 T 28-03-2018 IPR018946 Alkaline phosphatase D-related SMD44_RS40220 f369b8471916524baf0cdfc1863dec9a 521 Gene3D G3DSA:3.60.21.10 151 508 1.5E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS40220 f369b8471916524baf0cdfc1863dec9a 521 SUPERFAMILY SSF56300 154 479 1.98E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS40220 f369b8471916524baf0cdfc1863dec9a 521 Gene3D G3DSA:1.20.5.510 2 31 0.0022 T 28-03-2018 SMD44_RS40220 f369b8471916524baf0cdfc1863dec9a 521 Gene3D G3DSA:2.60.40.380 47 150 4.1E-4 T 28-03-2018 SMD44_RS09695 dd0140fc6b26c25b2a388253be9110b2 185 Gene3D G3DSA:3.40.630.30 23 185 5.9E-26 T 28-03-2018 SMD44_RS09695 dd0140fc6b26c25b2a388253be9110b2 185 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 25 183 6.4E-57 T 28-03-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 SMD44_RS09695 dd0140fc6b26c25b2a388253be9110b2 185 SUPERFAMILY SSF55729 18 155 6.8E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS09695 dd0140fc6b26c25b2a388253be9110b2 185 Pfam PF00583 Acetyltransferase (GNAT) family 54 145 3.3E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS39540 9c385e4f112794d66a1b465f89183996 307 Gene3D G3DSA:3.40.50.720 1 259 2.8E-29 T 28-03-2018 SMD44_RS39540 9c385e4f112794d66a1b465f89183996 307 Pfam PF05368 NmrA-like family 8 247 1.7E-45 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 SMD44_RS39540 9c385e4f112794d66a1b465f89183996 307 SUPERFAMILY SSF51735 8 268 1.92E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31450 225b11da0632d58ae7751aa4b12c5b9d 201 Pfam PF16291 Domain of unknown function (DUF4937 2 86 1.7E-29 T 28-03-2018 IPR032555 Domain of unknown function DUF4937 SMD44_RS31450 225b11da0632d58ae7751aa4b12c5b9d 201 SUPERFAMILY SSF54909 15 77 6.44E-6 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS31450 225b11da0632d58ae7751aa4b12c5b9d 201 Gene3D G3DSA:3.30.70.100 11 92 0.003 T 28-03-2018 SMD44_RS31450 225b11da0632d58ae7751aa4b12c5b9d 201 Gene3D G3DSA:3.30.70.100 93 191 1.2E-6 T 28-03-2018 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 SUPERFAMILY SSF48498 78 207 5.11E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 205 4.7E-16 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 Gene3D G3DSA:1.10.357.10 85 210 1.4E-28 T 28-03-2018 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.5E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 PRINTS PR00400 Tetracycline repressor protein signature 26 49 5.7E-12 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 PRINTS PR00400 Tetracycline repressor protein signature 79 98 5.7E-12 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 PRINTS PR00400 Tetracycline repressor protein signature 188 202 5.7E-12 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 SUPERFAMILY SSF46689 2 67 2.1E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 Gene3D G3DSA:1.10.10.60 50 84 3.4E-9 T 28-03-2018 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 Gene3D G3DSA:1.10.10.60 1 49 2.6E-19 T 28-03-2018 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 7.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS08590 b44e50f8a1d3dc911bbfed19674db40a 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 7.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS17585 b609483ace246d6f76fadea22b5ea722 370 Gene3D G3DSA:3.40.630.30 100 321 8.5E-21 T 28-03-2018 SMD44_RS17585 b609483ace246d6f76fadea22b5ea722 370 SUPERFAMILY SSF55729 160 321 3.28E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS17585 b609483ace246d6f76fadea22b5ea722 370 Pfam PF13480 Acetyltransferase (GNAT) domain 160 299 5.5E-36 T 28-03-2018 SMD44_RS23950 2bcd918915881669c8d18fc5062ec5e9 517 SUPERFAMILY SSF55874 246 366 9.37E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23950 2bcd918915881669c8d18fc5062ec5e9 517 Pfam PF07730 Histidine kinase 170 234 1.1E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS23950 2bcd918915881669c8d18fc5062ec5e9 517 Gene3D G3DSA:3.30.565.10 241 374 2.8E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14930 e3d1cc491092d471f7540d12ab61aeaa 147 SMART SM00347 28 127 0.0031 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS14930 e3d1cc491092d471f7540d12ab61aeaa 147 SUPERFAMILY SSF46785 11 137 3.16E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14930 e3d1cc491092d471f7540d12ab61aeaa 147 Gene3D G3DSA:1.10.10.10 2 140 5.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35360 8a94559f65b85fa71768dc199c654fc8 607 Gene3D G3DSA:3.40.50.980 195 393 4.1E-38 T 28-03-2018 SMD44_RS35360 8a94559f65b85fa71768dc199c654fc8 607 Gene3D G3DSA:3.30.300.30 472 607 6.6E-20 T 28-03-2018 SMD44_RS35360 8a94559f65b85fa71768dc199c654fc8 607 Pfam PF00501 AMP-binding enzyme 22 477 5.9E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS35360 8a94559f65b85fa71768dc199c654fc8 607 SUPERFAMILY SSF56801 8 292 7.72E-114 T 28-03-2018 SMD44_RS35360 8a94559f65b85fa71768dc199c654fc8 607 SUPERFAMILY SSF56801 344 605 7.72E-114 T 28-03-2018 SMD44_RS35360 8a94559f65b85fa71768dc199c654fc8 607 Gene3D G3DSA:3.40.50.980 11 194 1.7E-37 T 28-03-2018 SMD44_RS35360 8a94559f65b85fa71768dc199c654fc8 607 Gene3D G3DSA:2.30.38.10 394 470 5.8E-16 T 28-03-2018 SMD44_RS35360 8a94559f65b85fa71768dc199c654fc8 607 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 SUPERFAMILY SSF109998 245 434 1.96E-39 T 28-03-2018 IPR027304 Trigger factor/SurA domain SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 420 1.4E-38 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 Gene3D G3DSA:3.10.50.40 127 225 7.6E-8 T 28-03-2018 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 Hamap MF_00303 Trigger factor [tig]. 1 425 19.588 T 28-03-2018 IPR005215 Trigger factor GO:0015031 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 SUPERFAMILY SSF54534 133 244 3.14E-20 T 28-03-2018 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 215 3.7E-7 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 SUPERFAMILY SSF102735 3 131 4.58E-38 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 PIRSF PIRSF003095 1 446 2.3E-125 T 28-03-2018 IPR005215 Trigger factor GO:0015031 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 TIGRFAM TIGR00115 tig: trigger factor 12 418 3.7E-121 T 28-03-2018 IPR005215 Trigger factor GO:0015031 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 Gene3D G3DSA:1.10.3120.10 226 395 3.5E-40 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 Gene3D G3DSA:3.30.70.1050 1 119 3.5E-37 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMD44_RS14155 825f314f95d5fb201346051b628c91f0 466 Pfam PF05697 Bacterial trigger factor protein (TF) 3 145 3.5E-41 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 2.7E-31 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 322 2.4E-33 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 PIRSF PIRSF000102 2 326 3.0E-60 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 2.3E-145 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.331 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 Gene3D G3DSA:3.40.50.720 7 156 1.8E-25 T 28-03-2018 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 SUPERFAMILY SSF51735 5 156 1.94E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 SUPERFAMILY SSF56327 157 324 5.25E-61 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 Gene3D G3DSA:3.90.110.10 157 325 1.9E-54 T 28-03-2018 SMD44_RS26105 17b86ec5bdf91bfa2046872e7b5837fe 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 28-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 SMART SM00895 93 217 1.7E-19 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 SUPERFAMILY SSF46785 5 79 2.13E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 Pfam PF07729 FCD domain 93 215 1.9E-27 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 64 1.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 SMART SM00345 5 64 4.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 Gene3D G3DSA:1.20.120.530 87 230 6.6E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 Gene3D G3DSA:1.10.10.10 2 65 9.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 3.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 3.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15325 0498eda7af6ce0278d8c789111d5fe83 237 SUPERFAMILY SSF48008 89 222 1.57E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 PRINTS PR00046 Major sigma-70 factor signature 258 273 2.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 PRINTS PR00046 Major sigma-70 factor signature 241 253 2.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 PRINTS PR00046 Major sigma-70 factor signature 94 107 2.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 PRINTS PR00046 Major sigma-70 factor signature 273 284 2.6E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 SUPERFAMILY SSF88659 205 288 3.92E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 94 107 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 SUPERFAMILY SSF88659 143 218 2.83E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 Pfam PF04539 Sigma-70 region 3 151 209 1.7E-10 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 65 287 5.2E-95 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 Pfam PF04545 Sigma-70, region 4 237 286 5.4E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 67 287 8.3E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 Gene3D G3DSA:1.10.601.10 17 138 6.0E-24 T 28-03-2018 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 SUPERFAMILY SSF88946 44 139 4.19E-31 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 Gene3D G3DSA:1.10.10.10 228 290 2.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 Gene3D G3DSA:1.10.10.10 140 191 3.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20260 fb04a4bf77799b3e7c76d5a946e80e1c 291 Pfam PF04542 Sigma-70 region 2 70 139 1.4E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 Gene3D G3DSA:1.10.540.10 24 173 2.2E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 441 7.6E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 Gene3D G3DSA:2.40.110.10 174 273 1.7E-33 T 28-03-2018 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 SUPERFAMILY SSF56645 36 293 3.4E-59 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 65 170 3.8E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 Gene3D G3DSA:1.20.140.10 274 454 5.4E-42 T 28-03-2018 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 175 271 7.8E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 SUPERFAMILY SSF47203 285 442 1.61E-33 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS30780 5c21e48b4f3669ca340df4b89343c06a 649 Gene3D G3DSA:1.20.140.10 491 591 0.06 T 28-03-2018 SMD44_RS06520 b6e6b06ed32e79e9d6cc23937bf2880b 214 Pfam PF04299 Putative FMN-binding domain 11 167 3.9E-21 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type SMD44_RS06520 b6e6b06ed32e79e9d6cc23937bf2880b 214 Gene3D G3DSA:2.30.110.10 1 209 4.2E-43 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS06520 b6e6b06ed32e79e9d6cc23937bf2880b 214 SUPERFAMILY SSF50475 12 193 2.75E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS23340 bb933cf62de74e1b3d7ac4930d5d1dc4 1132 SUPERFAMILY SSF52540 509 708 1.02E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23340 bb933cf62de74e1b3d7ac4930d5d1dc4 1132 Hamap MF_00165 Thymidylate kinase [tmk]. 510 709 30.782 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMD44_RS23340 bb933cf62de74e1b3d7ac4930d5d1dc4 1132 ProSitePatterns PS01331 Thymidylate kinase signature. 599 611 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMD44_RS23340 bb933cf62de74e1b3d7ac4930d5d1dc4 1132 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 509 699 1.5E-51 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMD44_RS23340 bb933cf62de74e1b3d7ac4930d5d1dc4 1132 Gene3D G3DSA:3.40.50.300 485 782 2.5E-63 T 28-03-2018 SMD44_RS23340 bb933cf62de74e1b3d7ac4930d5d1dc4 1132 SUPERFAMILY SSF103473 70 484 2.35E-13 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS23340 bb933cf62de74e1b3d7ac4930d5d1dc4 1132 Pfam PF02223 Thymidylate kinase 514 699 2.0E-47 T 28-03-2018 SMD44_RS23340 bb933cf62de74e1b3d7ac4930d5d1dc4 1132 Gene3D G3DSA:1.20.1250.20 283 484 6.9E-12 T 28-03-2018 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 232 284 4.1E-20 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 Pfam PF00037 4Fe-4S binding domain 194 211 1.2E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 SUPERFAMILY SSF53706 194 285 1.49E-18 T 28-03-2018 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 Gene3D G3DSA:3.10.20.30 10 111 2.4E-10 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 Gene3D G3DSA:2.20.25.90 231 286 2.7E-20 T 28-03-2018 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 Pfam PF12837 4Fe-4S binding domain 147 165 1.6E-5 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 Gene3D G3DSA:3.30.70.20 112 230 4.9E-17 T 28-03-2018 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 SUPERFAMILY SSF54292 13 127 4.26E-29 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 235 253 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 SUPERFAMILY SSF54862 86 218 2.3E-24 T 28-03-2018 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 SMART SM00926 230 284 7.8E-19 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS34645 6428bcb726edc52f55c887b6ec008dfa 286 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 87 5.5E-22 T 28-03-2018 SMD44_RS23430 baaff698b9d3766bf358ce16bf1393f2 275 Gene3D G3DSA:1.10.260.40 9 92 6.5E-13 T 28-03-2018 SMD44_RS23430 baaff698b9d3766bf358ce16bf1393f2 275 SUPERFAMILY SSF47413 11 65 3.1E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS23430 baaff698b9d3766bf358ce16bf1393f2 275 Pfam PF13560 Helix-turn-helix domain 13 67 6.2E-12 T 28-03-2018 SMD44_RS23430 baaff698b9d3766bf358ce16bf1393f2 275 SMART SM00530 16 71 1.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 Gene3D G3DSA:1.10.1200.10 97 195 3.9E-11 T 28-03-2018 SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 Pfam PF00155 Aminotransferase class I and II 299 637 1.5E-54 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 SUPERFAMILY SSF47336 17 106 6.67E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 Gene3D G3DSA:3.40.640.10 313 541 3.3E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 SUPERFAMILY SSF47336 109 191 5.89E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 495 504 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 Gene3D G3DSA:1.10.1200.10 16 96 4.8E-8 T 28-03-2018 SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 Gene3D G3DSA:3.90.1150.10 542 648 4.4E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS36205 5a6a0e0061b0cde8fd8a3e83df2118f0 654 SUPERFAMILY SSF53383 258 647 1.75E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 Gene3D G3DSA:2.10.109.10 57 253 1.7E-49 T 28-03-2018 SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 SUPERFAMILY SSF51306 60 108 3.84E-48 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 SUPERFAMILY SSF51306 135 245 3.84E-48 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 Pfam PF00717 Peptidase S24-like 68 165 2.5E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 61 77 3.1E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 140 152 3.1E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 193 212 3.1E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 ProSitePatterns PS00761 Signal peptidases I signature 3. 198 211 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMD44_RS30510 447a392868cb0e07ca5e5a75fc7246b8 302 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 47 238 5.5E-42 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS34000 aa80307e3ea2d401567a5a4f0656d618 467 SUPERFAMILY SSF51338 362 462 1.45E-34 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS34000 aa80307e3ea2d401567a5a4f0656d618 467 Pfam PF01979 Amidohydrolase family 56 442 6.1E-24 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS34000 aa80307e3ea2d401567a5a4f0656d618 467 Gene3D G3DSA:3.20.20.140 68 284 2.6E-56 T 28-03-2018 SMD44_RS34000 aa80307e3ea2d401567a5a4f0656d618 467 Gene3D G3DSA:3.20.20.140 285 429 2.7E-42 T 28-03-2018 SMD44_RS34000 aa80307e3ea2d401567a5a4f0656d618 467 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 459 7.0E-170 T 28-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 SMD44_RS34000 aa80307e3ea2d401567a5a4f0656d618 467 SUPERFAMILY SSF51556 60 388 1.06E-104 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS34000 aa80307e3ea2d401567a5a4f0656d618 467 Gene3D G3DSA:2.30.40.10 1 67 9.8E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS34000 aa80307e3ea2d401567a5a4f0656d618 467 SUPERFAMILY SSF51338 4 77 1.14E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 Gene3D G3DSA:1.10.10.10 1 73 1.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 SUPERFAMILY SSF47979 65 137 3.53E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 Pfam PF04023 FeoA domain 154 228 8.1E-9 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 SMART SM00899 153 229 4.7E-6 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 SUPERFAMILY SSF50037 130 228 4.81E-22 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 Gene3D G3DSA:1.10.60.10 75 129 7.7E-25 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 1.5E-29 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 60 3.4E-16 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 SMART SM00529 26 125 2.1E-44 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 Gene3D G3DSA:2.30.30.90 130 229 1.1E-22 T 28-03-2018 SMD44_RS02770 ae0e78bbfab4d9f7155967e5d9190759 230 SUPERFAMILY SSF46785 2 60 1.65E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06230 03658510443107f43b7bf39dcd274b3f 345 Pfam PF02333 Phytase 17 344 2.3E-73 T 28-03-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 SMD44_RS06230 03658510443107f43b7bf39dcd274b3f 345 Gene3D G3DSA:2.120.10.30 31 345 1.1E-55 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS06230 03658510443107f43b7bf39dcd274b3f 345 SUPERFAMILY SSF50956 39 343 4.18E-67 T 28-03-2018 SMD44_RS09980 ddaaf60041d75a0903d333b6293b2e74 106 SUPERFAMILY SSF103481 6 104 8.24E-20 T 28-03-2018 SMD44_RS09980 ddaaf60041d75a0903d333b6293b2e74 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.7E-28 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMD44_RS32835 661b964eb2b8fcdb888d4e0bea157bd6 238 Gene3D G3DSA:3.40.50.620 3 238 1.1E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS32835 661b964eb2b8fcdb888d4e0bea157bd6 238 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 51 213 1.7E-40 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMD44_RS32835 661b964eb2b8fcdb888d4e0bea157bd6 238 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 7 238 35.458 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 SMD44_RS32835 661b964eb2b8fcdb888d4e0bea157bd6 238 PIRSF PIRSF000857 1 238 4.4E-89 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 SMD44_RS32835 661b964eb2b8fcdb888d4e0bea157bd6 238 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 32 237 1.1E-58 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 SMD44_RS32835 661b964eb2b8fcdb888d4e0bea157bd6 238 SUPERFAMILY SSF52402 23 199 3.85E-49 T 28-03-2018 SMD44_RS34820 b957e614fded86dd074859bd6e44c701 529 Gene3D G3DSA:3.40.309.10 302 476 1.7E-28 T 28-03-2018 SMD44_RS34820 b957e614fded86dd074859bd6e44c701 529 Pfam PF00171 Aldehyde dehydrogenase family 62 505 1.3E-93 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS34820 b957e614fded86dd074859bd6e44c701 529 SUPERFAMILY SSF53720 52 508 6.68E-76 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS34820 b957e614fded86dd074859bd6e44c701 529 Gene3D G3DSA:3.40.605.10 38 301 3.1E-39 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 Gene3D G3DSA:3.30.390.30 331 420 2.0E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 313 8.7E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 Gene3D G3DSA:3.50.50.60 109 191 4.8E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 SUPERFAMILY SSF51905 153 323 4.48E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 Gene3D G3DSA:3.50.50.60 2 108 2.4E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 9.6E-25 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.6E-25 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 9.6E-25 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 9.6E-25 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 9.6E-25 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 Pfam PF14759 Reductase C-terminal 333 419 7.2E-18 T 28-03-2018 IPR028202 Reductase, C-terminal SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 SUPERFAMILY SSF55424 325 419 4.53E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 SUPERFAMILY SSF51905 6 198 3.42E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 4.0E-16 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 4.0E-16 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.0E-16 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 4.0E-16 T 28-03-2018 SMD44_RS13335 d07981751bbe7f82e0d1c32bd112d71f 420 Gene3D G3DSA:3.50.50.60 192 330 1.8E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 Pfam PF03466 LysR substrate binding domain 104 297 4.5E-22 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 SUPERFAMILY SSF46785 8 126 3.45E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 2.6E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 SUPERFAMILY SSF53850 104 298 3.88E-23 T 28-03-2018 SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 Gene3D G3DSA:3.40.190.10 198 271 7.6E-6 T 28-03-2018 SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 Gene3D G3DSA:1.10.10.10 1 91 6.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30000 14f4e367708d76c5d83e215b7337738f 300 Gene3D G3DSA:3.40.190.10 101 197 3.0E-17 T 28-03-2018 SMD44_RS04960 e99f60d7eba62781d15c1565d4970122 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 4.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS04960 e99f60d7eba62781d15c1565d4970122 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 193 4.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS04960 e99f60d7eba62781d15c1565d4970122 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 138 4.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS04960 e99f60d7eba62781d15c1565d4970122 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 200 213 4.3E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS04960 e99f60d7eba62781d15c1565d4970122 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 98 208 7.0E-12 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS04960 e99f60d7eba62781d15c1565d4970122 236 Gene3D G3DSA:3.40.50.1000 1 217 2.9E-26 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS04960 e99f60d7eba62781d15c1565d4970122 236 SUPERFAMILY SSF56784 3 219 2.25E-34 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS04960 e99f60d7eba62781d15c1565d4970122 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 118 202 4.8E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 Pfam PF00005 ABC transporter 283 434 4.8E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 Pfam PF00005 ABC transporter 23 174 6.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 SMART SM00382 289 483 1.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 SMART SM00382 32 222 2.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 SUPERFAMILY SSF52540 6 232 2.07E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 SUPERFAMILY SSF52540 282 495 1.24E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 Gene3D G3DSA:3.40.50.300 280 502 2.3E-38 T 28-03-2018 SMD44_RS34710 0df719e645e01c326d91202b13c84cae 528 Gene3D G3DSA:3.40.50.300 4 236 1.7E-52 T 28-03-2018 SMD44_RS07360 eb609f415e397e0a71d94de08b849f52 746 SUPERFAMILY SSF48452 460 653 7.21E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS07360 eb609f415e397e0a71d94de08b849f52 746 Gene3D G3DSA:1.25.40.10 403 646 2.3E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS07360 eb609f415e397e0a71d94de08b849f52 746 SUPERFAMILY SSF52540 37 257 5.75E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07360 eb609f415e397e0a71d94de08b849f52 746 Gene3D G3DSA:3.40.50.300 34 174 1.7E-9 T 28-03-2018 SMD44_RS07360 eb609f415e397e0a71d94de08b849f52 746 PRINTS PR00364 Disease resistance protein signature 130 144 1.6E-6 T 28-03-2018 SMD44_RS07360 eb609f415e397e0a71d94de08b849f52 746 PRINTS PR00364 Disease resistance protein signature 224 238 1.6E-6 T 28-03-2018 SMD44_RS07360 eb609f415e397e0a71d94de08b849f52 746 PRINTS PR00364 Disease resistance protein signature 63 78 1.6E-6 T 28-03-2018 SMD44_RS01180 4d69dc62499ce3c15724703500dada4e 503 Gene3D G3DSA:3.40.50.1820 33 484 8.2E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01180 4d69dc62499ce3c15724703500dada4e 503 SUPERFAMILY SSF53474 70 132 9.36E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01180 4d69dc62499ce3c15724703500dada4e 503 SUPERFAMILY SSF53474 297 373 9.36E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01180 4d69dc62499ce3c15724703500dada4e 503 SUPERFAMILY SSF53474 162 220 9.36E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01180 4d69dc62499ce3c15724703500dada4e 503 SUPERFAMILY SSF53474 406 480 9.36E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01180 4d69dc62499ce3c15724703500dada4e 503 Pfam PF08386 TAP-like protein 401 488 2.7E-11 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD44_RS01180 4d69dc62499ce3c15724703500dada4e 503 Pfam PF00561 alpha/beta hydrolase fold 82 230 2.5E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS18935 8de1b489d748705169bfb0631cae7aa1 326 Pfam PF03537 Glycoside-hydrolase family GH114 54 314 1.4E-48 T 28-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain SMD44_RS18935 8de1b489d748705169bfb0631cae7aa1 326 Gene3D G3DSA:3.20.20.70 40 323 2.1E-41 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS18935 8de1b489d748705169bfb0631cae7aa1 326 SUPERFAMILY SSF51445 68 312 1.03E-25 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS30875 4087410532d4446024aac730d630c79c 164 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 SMD44_RS30875 4087410532d4446024aac730d630c79c 164 Pfam PF02033 Ribosome-binding factor A 6 110 2.0E-26 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SMD44_RS30875 4087410532d4446024aac730d630c79c 164 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 111 1.7E-22 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SMD44_RS30875 4087410532d4446024aac730d630c79c 164 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 20.329 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SMD44_RS30875 4087410532d4446024aac730d630c79c 164 SUPERFAMILY SSF89919 2 113 8.76E-31 T 28-03-2018 IPR023799 Ribosome-binding factor A domain SMD44_RS30875 4087410532d4446024aac730d630c79c 164 Gene3D G3DSA:3.30.300.20 4 117 1.2E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS30875 4087410532d4446024aac730d630c79c 164 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 97 1.0E-40 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SMD44_RS10020 1ea53cd95335d100f13a5c12bcb017a5 247 Pfam PF01022 Bacterial regulatory protein, arsR family 25 70 1.8E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS10020 1ea53cd95335d100f13a5c12bcb017a5 247 Gene3D G3DSA:1.10.10.10 17 180 6.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10020 1ea53cd95335d100f13a5c12bcb017a5 247 SUPERFAMILY SSF46785 26 209 6.92E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 324 2.3E-48 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1038 1181 1.5E-9 T 28-03-2018 SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 SUPERFAMILY SSF52540 17 487 5.54E-112 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 SUPERFAMILY SSF52540 729 775 5.54E-112 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 SUPERFAMILY SSF52540 543 690 5.54E-112 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 Gene3D G3DSA:3.90.320.10 979 1181 6.6E-12 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 SUPERFAMILY SSF52980 1039 1168 8.85E-5 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 Gene3D G3DSA:3.40.50.300 366 807 3.6E-61 T 28-03-2018 SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 Pfam PF13361 UvrD-like helicase C-terminal domain 336 747 1.2E-27 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD44_RS28075 e1df3beb724f206700e95a50ea1e176e 1224 Gene3D G3DSA:3.40.50.300 9 337 5.8E-47 T 28-03-2018 SMD44_RS19185 1f85e151fe3845e6fd3c1d10be4cdc5f 347 Gene3D G3DSA:3.40.50.300 26 311 5.9E-68 T 28-03-2018 SMD44_RS19185 1f85e151fe3845e6fd3c1d10be4cdc5f 347 Pfam PF00005 ABC transporter 50 193 3.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19185 1f85e151fe3845e6fd3c1d10be4cdc5f 347 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 48 334 5.9E-97 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD44_RS19185 1f85e151fe3845e6fd3c1d10be4cdc5f 347 SMART SM00382 59 250 3.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19185 1f85e151fe3845e6fd3c1d10be4cdc5f 347 SUPERFAMILY SSF52540 28 255 1.97E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19185 1f85e151fe3845e6fd3c1d10be4cdc5f 347 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 SUPERFAMILY SSF53335 325 386 7.67E-63 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 SUPERFAMILY SSF53335 10 289 7.67E-63 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 364 382 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 10 26 9.2E-11 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 131 145 9.2E-11 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 193 206 9.2E-11 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 Gene3D G3DSA:3.90.120.10 337 370 2.0E-8 T 28-03-2018 SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 93 105 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 Pfam PF00145 C-5 cytosine-specific DNA methylase 10 382 2.1E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 12 382 3.5E-37 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD44_RS15495 c6eadea39100809cfc5a0917f4b90392 397 Gene3D G3DSA:3.40.50.150 1 262 1.6E-49 T 28-03-2018 SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 Pfam PF07690 Major Facilitator Superfamily 6 399 1.0E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 3 410 1.5E-78 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 SUPERFAMILY SSF103473 1 183 3.4E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 SUPERFAMILY SSF103473 236 461 3.4E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 Gene3D G3DSA:1.20.1250.20 1 188 2.0E-32 T 28-03-2018 SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 Gene3D G3DSA:1.20.1250.20 247 467 1.6E-29 T 28-03-2018 SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 ProSitePatterns PS00216 Sugar transport proteins signature 1. 55 71 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 126 150 4.0E-5 T 28-03-2018 SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 191 209 4.0E-5 T 28-03-2018 SMD44_RS03085 0a9b449cff3d51cdb27727ca4ab4b4bd 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 4 28 4.0E-5 T 28-03-2018 SMD44_RS24130 666346d050cdd826e52e31d5a95cd33e 321 Pfam PF12710 haloacid dehalogenase-like hydrolase 71 257 1.7E-28 T 28-03-2018 SMD44_RS24130 666346d050cdd826e52e31d5a95cd33e 321 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 70 260 4.4E-15 T 28-03-2018 SMD44_RS24130 666346d050cdd826e52e31d5a95cd33e 321 SUPERFAMILY SSF56784 68 283 9.21E-30 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS24130 666346d050cdd826e52e31d5a95cd33e 321 Gene3D G3DSA:3.40.50.1000 67 295 2.8E-22 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS24130 666346d050cdd826e52e31d5a95cd33e 321 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 70 272 1.2E-53 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like SMD44_RS35730 ba0bb46f6e42630e2830ea2109c1ee8f 301 Gene3D G3DSA:1.10.101.10 226 301 1.2E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS35730 ba0bb46f6e42630e2830ea2109c1ee8f 301 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 181 1.3E-15 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS35730 ba0bb46f6e42630e2830ea2109c1ee8f 301 Gene3D G3DSA:3.40.80.10 3 204 9.9E-25 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS35730 ba0bb46f6e42630e2830ea2109c1ee8f 301 SUPERFAMILY SSF55846 18 197 7.59E-22 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS35730 ba0bb46f6e42630e2830ea2109c1ee8f 301 SMART SM00644 27 181 2.6E-11 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS35730 ba0bb46f6e42630e2830ea2109c1ee8f 301 SUPERFAMILY SSF47090 224 300 2.17E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 SMART SM00244 21 179 1.2E-52 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 SUPERFAMILY SSF117892 52 186 1.1E-39 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 PRINTS PR00721 Stomatin signature 111 128 6.3E-32 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 PRINTS PR00721 Stomatin signature 131 154 6.3E-32 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 PRINTS PR00721 Stomatin signature 28 50 6.3E-32 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 PRINTS PR00721 Stomatin signature 76 97 6.3E-32 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 PRINTS PR00721 Stomatin signature 174 195 6.3E-32 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 PRINTS PR00721 Stomatin signature 155 173 6.3E-32 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site SMD44_RS00500 9ffba566cc540ed868d1323164b2f8b2 361 Pfam PF01145 SPFH domain / Band 7 family 25 195 1.1E-36 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS40495 1c0ead67b49f9dda6cae7487549a627a 301 SUPERFAMILY SSF49899 60 298 7.93E-20 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS40495 1c0ead67b49f9dda6cae7487549a627a 301 Pfam PF00722 Glycosyl hydrolases family 16 165 258 2.0E-7 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 SMD44_RS40495 1c0ead67b49f9dda6cae7487549a627a 301 Gene3D G3DSA:2.60.120.200 55 298 5.0E-23 T 28-03-2018 SMD44_RS11380 ff17016b2f0e59278d4c36d995b88712 269 PIRSF PIRSF000007 1 263 4.8E-128 T 28-03-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 SMD44_RS11380 ff17016b2f0e59278d4c36d995b88712 269 SUPERFAMILY SSF46626 13 126 3.78E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD44_RS11380 ff17016b2f0e59278d4c36d995b88712 269 SUPERFAMILY SSF46626 124 217 4.14E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD44_RS11380 ff17016b2f0e59278d4c36d995b88712 269 Gene3D G3DSA:1.10.760.10 24 136 5.0E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD44_RS11380 ff17016b2f0e59278d4c36d995b88712 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 142 216 3.7E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD44_RS11380 ff17016b2f0e59278d4c36d995b88712 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 48 122 2.0E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD44_RS11380 ff17016b2f0e59278d4c36d995b88712 269 Gene3D G3DSA:1.10.760.10 137 269 6.1E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD44_RS12530 f8d45b4607e0395ff25ac0903df270db 578 SUPERFAMILY SSF56300 154 251 1.14E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS12530 f8d45b4607e0395ff25ac0903df270db 578 SUPERFAMILY SSF56300 422 470 1.14E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS12530 f8d45b4607e0395ff25ac0903df270db 578 SUPERFAMILY SSF56300 301 389 1.14E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS12530 f8d45b4607e0395ff25ac0903df270db 578 Gene3D G3DSA:3.60.21.10 128 569 7.9E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS12530 f8d45b4607e0395ff25ac0903df270db 578 Pfam PF09423 PhoD-like phosphatase 168 490 2.8E-14 T 28-03-2018 IPR018946 Alkaline phosphatase D-related SMD44_RS15795 4c646ca500caf15cb37a600172c4f2c6 213 SMART SM00346 6 93 9.5E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS15795 4c646ca500caf15cb37a600172c4f2c6 213 Gene3D G3DSA:3.30.450.40 73 148 1.0E-15 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS15795 4c646ca500caf15cb37a600172c4f2c6 213 SUPERFAMILY SSF55781 67 212 5.4E-21 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS15795 4c646ca500caf15cb37a600172c4f2c6 213 Gene3D G3DSA:1.10.10.10 1 72 1.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15795 4c646ca500caf15cb37a600172c4f2c6 213 SUPERFAMILY SSF46785 7 76 6.58E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15795 4c646ca500caf15cb37a600172c4f2c6 213 Pfam PF09339 IclR helix-turn-helix domain 8 58 1.1E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS15795 4c646ca500caf15cb37a600172c4f2c6 213 Gene3D G3DSA:3.30.450.40 149 213 5.6E-9 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 Gene3D G3DSA:2.140.10.10 295 460 1.0E-6 T 28-03-2018 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 Gene3D G3DSA:2.140.10.10 573 698 3.5E-21 T 28-03-2018 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 Gene3D G3DSA:2.140.10.10 461 572 2.3E-5 T 28-03-2018 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 Pfam PF13360 PQQ-like domain 423 546 3.4E-7 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 Pfam PF13360 PQQ-like domain 581 696 1.1E-13 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 Gene3D G3DSA:3.30.200.20 5 105 1.6E-11 T 28-03-2018 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 42 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 Gene3D G3DSA:1.10.510.10 106 291 4.9E-43 T 28-03-2018 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 SMART SM00564 626 658 1.5E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 SMART SM00564 395 438 100.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 SMART SM00564 587 618 2.0E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 Pfam PF00069 Protein kinase domain 16 263 3.0E-38 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 SMART SM00220 14 266 1.1E-41 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 SUPERFAMILY SSF50998 422 689 7.85E-20 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS14170 940c9c9731b3511afb044a1c3b667812 699 SUPERFAMILY SSF56112 11 278 2.83E-61 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS11075 be2dc35180bc9e666555a5298147c764 187 Pfam PF00484 Carbonic anhydrase 55 119 2.0E-10 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS11075 be2dc35180bc9e666555a5298147c764 187 Gene3D G3DSA:3.40.1050.10 23 187 1.0E-30 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS11075 be2dc35180bc9e666555a5298147c764 187 SUPERFAMILY SSF53056 25 185 4.06E-34 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS11075 be2dc35180bc9e666555a5298147c764 187 SMART SM00947 47 185 8.0E-23 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS26160 7097b04dd357417767acae719c0ef126 509 Gene3D G3DSA:3.40.309.10 279 481 9.4E-70 T 28-03-2018 SMD44_RS26160 7097b04dd357417767acae719c0ef126 509 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS26160 7097b04dd357417767acae719c0ef126 509 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS26160 7097b04dd357417767acae719c0ef126 509 SUPERFAMILY SSF53720 14 499 1.7E-157 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS26160 7097b04dd357417767acae719c0ef126 509 Pfam PF00171 Aldehyde dehydrogenase family 22 495 1.1E-161 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS26160 7097b04dd357417767acae719c0ef126 509 Gene3D G3DSA:3.40.605.10 4 278 2.0E-88 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS07650 d1ec6a53d2acc4bf3e424e19e73bb8a5 272 SUPERFAMILY SSF55315 6 106 1.58E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SMD44_RS07650 d1ec6a53d2acc4bf3e424e19e73bb8a5 272 Gene3D G3DSA:3.40.1280.10 105 269 1.4E-47 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD44_RS07650 d1ec6a53d2acc4bf3e424e19e73bb8a5 272 SUPERFAMILY SSF75217 101 266 1.24E-38 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SMD44_RS07650 d1ec6a53d2acc4bf3e424e19e73bb8a5 272 Pfam PF00588 SpoU rRNA Methylase family 121 263 4.0E-34 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMD44_RS07650 d1ec6a53d2acc4bf3e424e19e73bb8a5 272 Gene3D G3DSA:3.30.1330.30 6 104 2.1E-22 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 SUPERFAMILY SSF46689 284 333 2.39E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 24 203 1.2E-48 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 Gene3D G3DSA:1.10.10.10 261 285 0.011 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 Pfam PF12833 Helix-turn-helix domain 255 332 4.2E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 315 331 8.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 315 8.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 SMART SM00342 248 331 2.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 Gene3D G3DSA:1.10.10.60 286 338 2.7E-12 T 28-03-2018 SMD44_RS24475 3e323237ea4c37b46697cf73eaf97ed5 386 Gene3D G3DSA:1.10.10.10 228 260 3.9E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04595 3b0d9eceaa5650a16d5596b64f7eef46 109 Gene3D G3DSA:1.20.5.320 26 59 0.0026 T 28-03-2018 SMD44_RS06045 093c201b0590665b4317ba4a91aad92a 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 8.3E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS06045 093c201b0590665b4317ba4a91aad92a 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 8.3E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS06045 093c201b0590665b4317ba4a91aad92a 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 8.3E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS06045 093c201b0590665b4317ba4a91aad92a 285 SUPERFAMILY SSF53474 27 282 7.53E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06045 093c201b0590665b4317ba4a91aad92a 285 Pfam PF12697 Alpha/beta hydrolase family 40 278 9.3E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS06045 093c201b0590665b4317ba4a91aad92a 285 Gene3D G3DSA:3.40.50.1820 24 283 2.7E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24480 d3b960ba648c9a8411f9bda8ee837d2c 201 Gene3D G3DSA:2.60.120.10 89 200 7.6E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS24480 d3b960ba648c9a8411f9bda8ee837d2c 201 SUPERFAMILY SSF51182 78 198 1.36E-17 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS24480 d3b960ba648c9a8411f9bda8ee837d2c 201 SUPERFAMILY SSF47413 26 90 2.12E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS24480 d3b960ba648c9a8411f9bda8ee837d2c 201 Pfam PF01381 Helix-turn-helix 31 84 3.4E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS24480 d3b960ba648c9a8411f9bda8ee837d2c 201 Gene3D G3DSA:1.10.260.40 22 88 7.5E-16 T 28-03-2018 SMD44_RS24480 d3b960ba648c9a8411f9bda8ee837d2c 201 SMART SM00530 30 85 2.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 63 77 1.2E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 189 203 1.2E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 146 163 1.2E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 125 145 1.2E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 165 188 1.2E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 Gene3D G3DSA:2.40.10.10 37 120 3.4E-14 T 28-03-2018 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 SUPERFAMILY SSF50494 44 217 1.41E-26 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 Pfam PF00089 Trypsin 116 215 6.1E-6 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 Gene3D G3DSA:2.40.10.10 121 211 2.5E-18 T 28-03-2018 SMD44_RS33430 0614d1af87d41d04f9a6da816f9fa58b 228 PIRSF PIRSF001134 9 226 1.5E-71 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD44_RS31850 59087a8462ef5a6b92dc90e50ea33821 532 Gene3D G3DSA:3.40.50.980 22 174 3.9E-34 T 28-03-2018 SMD44_RS31850 59087a8462ef5a6b92dc90e50ea33821 532 Gene3D G3DSA:3.40.50.980 175 340 1.1E-28 T 28-03-2018 SMD44_RS31850 59087a8462ef5a6b92dc90e50ea33821 532 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS31850 59087a8462ef5a6b92dc90e50ea33821 532 Pfam PF00501 AMP-binding enzyme 32 434 4.4E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS31850 59087a8462ef5a6b92dc90e50ea33821 532 Gene3D G3DSA:2.30.38.10 353 428 2.4E-23 T 28-03-2018 SMD44_RS31850 59087a8462ef5a6b92dc90e50ea33821 532 Gene3D G3DSA:3.30.300.30 429 531 6.7E-26 T 28-03-2018 SMD44_RS31850 59087a8462ef5a6b92dc90e50ea33821 532 SUPERFAMILY SSF56801 8 528 1.83E-133 T 28-03-2018 SMD44_RS31850 59087a8462ef5a6b92dc90e50ea33821 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 517 4.1E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 SMART SM00865 204 321 3.9E-57 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 Gene3D G3DSA:3.40.50.1440 6 211 6.4E-42 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 9.2E-38 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 366 38.92 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 Gene3D G3DSA:3.30.1330.20 212 319 2.5E-46 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 SMART SM00864 10 202 2.8E-110 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 SUPERFAMILY SSF55307 201 315 5.72E-44 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 316 1.2E-128 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.5E-35 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.5E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.5E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.5E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.5E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD44_RS11015 3cad468abeb3cebed4fbfcd949d4f67d 408 SUPERFAMILY SSF52490 9 205 9.16E-68 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD44_RS11025 86f498808a36963c2af249695c167f6a 273 Pfam PF08478 POTRA domain, FtsQ-type 67 135 4.9E-16 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type SMD44_RS11025 86f498808a36963c2af249695c167f6a 273 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 36 271 17.87 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 SMD44_RS11025 86f498808a36963c2af249695c167f6a 273 Pfam PF03799 Cell division protein FtsQ 142 257 7.6E-6 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB SMD44_RS30275 3f40449b2577b09c07607b1b33304463 266 SUPERFAMILY SSF69593 4 229 1.44E-42 T 28-03-2018 SMD44_RS30275 3f40449b2577b09c07607b1b33304463 266 Gene3D G3DSA:3.40.1130.10 11 233 4.1E-48 T 28-03-2018 SMD44_RS30275 3f40449b2577b09c07607b1b33304463 266 Pfam PF01553 Acyltransferase 30 155 5.5E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS30275 3f40449b2577b09c07607b1b33304463 266 SMART SM00563 41 159 3.3E-35 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS36720 53a97124a94fadfa063fa32bbbe78052 178 Gene3D G3DSA:1.20.1250.20 1 177 2.5E-15 T 28-03-2018 SMD44_RS36720 53a97124a94fadfa063fa32bbbe78052 178 SUPERFAMILY SSF103473 3 172 2.49E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS36720 53a97124a94fadfa063fa32bbbe78052 178 Pfam PF07690 Major Facilitator Superfamily 3 137 4.7E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS21815 9b76454a2fcee65b5b84795b5b3f6bf2 412 SUPERFAMILY SSF52518 65 394 1.22E-98 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS21815 9b76454a2fcee65b5b84795b5b3f6bf2 412 Pfam PF00676 Dehydrogenase E1 component 82 361 4.1E-79 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SMD44_RS21815 9b76454a2fcee65b5b84795b5b3f6bf2 412 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 49 390 8.2E-136 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD44_RS21815 9b76454a2fcee65b5b84795b5b3f6bf2 412 Gene3D G3DSA:3.40.50.970 2 391 2.1E-92 T 28-03-2018 SMD44_RS30555 f2e98cecd5e9cc92765f8c9d8eb72eac 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30555 f2e98cecd5e9cc92765f8c9d8eb72eac 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30555 f2e98cecd5e9cc92765f8c9d8eb72eac 185 SUPERFAMILY SSF46689 4 74 1.35E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS30555 f2e98cecd5e9cc92765f8c9d8eb72eac 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 3.9E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30555 f2e98cecd5e9cc92765f8c9d8eb72eac 185 Gene3D G3DSA:1.10.10.60 6 54 1.8E-13 T 28-03-2018 SMD44_RS30555 f2e98cecd5e9cc92765f8c9d8eb72eac 185 Gene3D G3DSA:1.10.357.10 55 185 7.0E-11 T 28-03-2018 SMD44_RS30555 f2e98cecd5e9cc92765f8c9d8eb72eac 185 SUPERFAMILY SSF48498 79 184 5.13E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS07830 0b601d3761eec011e8fc30e894df5b22 329 Gene3D G3DSA:3.20.20.100 4 327 2.2E-109 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS07830 0b601d3761eec011e8fc30e894df5b22 329 PRINTS PR00069 Aldo-keto reductase signature 43 67 2.3E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS07830 0b601d3761eec011e8fc30e894df5b22 329 PRINTS PR00069 Aldo-keto reductase signature 109 127 2.3E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS07830 0b601d3761eec011e8fc30e894df5b22 329 PRINTS PR00069 Aldo-keto reductase signature 140 157 2.3E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS07830 0b601d3761eec011e8fc30e894df5b22 329 Pfam PF00248 Aldo/keto reductase family 18 308 9.0E-79 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS07830 0b601d3761eec011e8fc30e894df5b22 329 SUPERFAMILY SSF51430 12 308 1.05E-99 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS12480 91a556e7641078dc748f7a9853ca1696 224 Gene3D G3DSA:3.40.50.150 2 224 5.1E-40 T 28-03-2018 SMD44_RS12480 91a556e7641078dc748f7a9853ca1696 224 Pfam PF01596 O-methyltransferase 35 186 2.7E-37 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 SMD44_RS12480 91a556e7641078dc748f7a9853ca1696 224 SUPERFAMILY SSF53335 9 222 1.5E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS01530 7227bf038f4cd5da512765cab0a2b5e3 480 SUPERFAMILY SSF53474 367 427 3.74E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01530 7227bf038f4cd5da512765cab0a2b5e3 480 SUPERFAMILY SSF53474 318 338 3.74E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01530 7227bf038f4cd5da512765cab0a2b5e3 480 SUPERFAMILY SSF53474 142 260 3.74E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01530 7227bf038f4cd5da512765cab0a2b5e3 480 Gene3D G3DSA:3.40.50.1820 22 452 4.4E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01530 7227bf038f4cd5da512765cab0a2b5e3 480 Pfam PF07519 Tannase and feruloyl esterase 122 248 2.0E-10 T 28-03-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 SMD44_RS01530 7227bf038f4cd5da512765cab0a2b5e3 480 Pfam PF10605 3HB-oligomer hydrolase (3HBOH) 358 461 1.8E-7 T 28-03-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 SMD44_RS08795 474591d32c8a94c80f1ced5356376d8d 345 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 207 1.1E-41 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMD44_RS08795 474591d32c8a94c80f1ced5356376d8d 345 SUPERFAMILY SSF81296 31 211 2.52E-48 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS08795 474591d32c8a94c80f1ced5356376d8d 345 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 302 336 0.0031 T 28-03-2018 SMD44_RS08795 474591d32c8a94c80f1ced5356376d8d 345 Gene3D G3DSA:2.70.50.50 31 210 4.9E-60 T 28-03-2018 SMD44_RS18480 5387bfd22e75c95722809da971471330 150 SUPERFAMILY SSF159888 50 107 9.68E-11 T 28-03-2018 SMD44_RS18480 5387bfd22e75c95722809da971471330 150 Pfam PF08818 Domain of unknown function (DU1801) 60 149 2.4E-7 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 SMD44_RS30800 2b72626c2acc2d2caa200566dfb833c8 332 Gene3D G3DSA:3.40.50.2300 62 180 4.2E-33 T 28-03-2018 SMD44_RS30800 2b72626c2acc2d2caa200566dfb833c8 332 Gene3D G3DSA:3.40.50.2300 181 312 3.9E-34 T 28-03-2018 SMD44_RS30800 2b72626c2acc2d2caa200566dfb833c8 332 Gene3D G3DSA:1.10.260.40 9 61 5.3E-19 T 28-03-2018 SMD44_RS30800 2b72626c2acc2d2caa200566dfb833c8 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 1.8E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS30800 2b72626c2acc2d2caa200566dfb833c8 332 SUPERFAMILY SSF47413 8 66 4.5E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS30800 2b72626c2acc2d2caa200566dfb833c8 332 Pfam PF13377 Periplasmic binding protein-like domain 176 328 3.2E-34 T 28-03-2018 SMD44_RS30800 2b72626c2acc2d2caa200566dfb833c8 332 SMART SM00354 8 78 7.2E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS30800 2b72626c2acc2d2caa200566dfb833c8 332 SUPERFAMILY SSF53822 65 322 2.36E-54 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS24540 b6979896ee31d629521c866534472d37 319 Gene3D G3DSA:1.10.3720.10 4 304 6.6E-43 T 28-03-2018 SMD44_RS24540 b6979896ee31d629521c866534472d37 319 SUPERFAMILY SSF161098 98 298 4.97E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS24540 b6979896ee31d629521c866534472d37 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 315 3.7E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS31820 a607cbd10ce43c15a103b79d37d849b1 318 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS31820 a607cbd10ce43c15a103b79d37d849b1 318 SMART SM00382 32 216 9.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31820 a607cbd10ce43c15a103b79d37d849b1 318 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 15 307 7.4E-98 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD44_RS31820 a607cbd10ce43c15a103b79d37d849b1 318 SUPERFAMILY SSF52540 7 228 6.96E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31820 a607cbd10ce43c15a103b79d37d849b1 318 Gene3D G3DSA:3.40.50.300 4 293 5.6E-62 T 28-03-2018 SMD44_RS31820 a607cbd10ce43c15a103b79d37d849b1 318 Pfam PF00005 ABC transporter 23 166 4.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS34655 8f0c6eb05a3e09732a8e8eecbd6c0572 663 Gene3D G3DSA:3.40.50.740 228 504 1.7E-84 T 28-03-2018 SMD44_RS34655 8f0c6eb05a3e09732a8e8eecbd6c0572 663 Gene3D G3DSA:3.40.228.10 136 227 3.2E-21 T 28-03-2018 SMD44_RS34655 8f0c6eb05a3e09732a8e8eecbd6c0572 663 Gene3D G3DSA:2.40.40.20 506 655 2.8E-32 T 28-03-2018 SMD44_RS34655 8f0c6eb05a3e09732a8e8eecbd6c0572 663 Gene3D G3DSA:3.40.50.740 29 135 5.8E-27 T 28-03-2018 SMD44_RS34655 8f0c6eb05a3e09732a8e8eecbd6c0572 663 SUPERFAMILY SSF50692 534 655 4.97E-30 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SMD44_RS34655 8f0c6eb05a3e09732a8e8eecbd6c0572 663 Pfam PF01568 Molydopterin dinucleotide binding domain 544 647 3.0E-25 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD44_RS34655 8f0c6eb05a3e09732a8e8eecbd6c0572 663 SUPERFAMILY SSF53706 21 499 1.11E-163 T 28-03-2018 SMD44_RS34655 8f0c6eb05a3e09732a8e8eecbd6c0572 663 Pfam PF00384 Molybdopterin oxidoreductase 29 454 2.9E-81 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS03275 444d76e8d4f71763d6883362c7ef9467 333 SUPERFAMILY SSF48576 22 327 2.36E-43 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS03275 444d76e8d4f71763d6883362c7ef9467 333 Gene3D G3DSA:1.10.600.10 14 328 3.0E-62 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS32275 c353bc3256b39457f94302b3f93eaae4 482 Pfam PF13416 Bacterial extracellular solute-binding protein 92 393 2.9E-23 T 28-03-2018 SMD44_RS32275 c353bc3256b39457f94302b3f93eaae4 482 Gene3D G3DSA:3.40.190.10 71 259 7.6E-29 T 28-03-2018 SMD44_RS32275 c353bc3256b39457f94302b3f93eaae4 482 SUPERFAMILY SSF53850 40 472 2.45E-54 T 28-03-2018 SMD44_RS32275 c353bc3256b39457f94302b3f93eaae4 482 Gene3D G3DSA:3.40.190.10 267 425 4.2E-4 T 28-03-2018 SMD44_RS32275 c353bc3256b39457f94302b3f93eaae4 482 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 34 474 1.2E-158 T 28-03-2018 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein SMD44_RS31990 68e06dad7aab3c722c5c893fd9a83b98 282 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 24 169 5.9E-19 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMD44_RS31990 68e06dad7aab3c722c5c893fd9a83b98 282 SUPERFAMILY SSF56176 20 169 1.58E-28 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS31990 68e06dad7aab3c722c5c893fd9a83b98 282 Gene3D G3DSA:3.30.465.10 53 169 1.1E-26 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS22665 58a3d35e7127ac2103b4d6c43ad99763 281 Gene3D G3DSA:3.40.50.10330 1 123 1.6E-9 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMD44_RS22665 58a3d35e7127ac2103b4d6c43ad99763 281 SUPERFAMILY SSF111331 1 122 5.89E-8 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SUPERFAMILY SSF52540 254 519 1.74E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Gene3D G3DSA:3.30.70.100 670 742 8.9E-5 T 28-03-2018 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SUPERFAMILY SSF48452 710 735 7.59E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SUPERFAMILY SSF48452 782 935 7.59E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SMART SM01043 90 234 4.9E-51 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Gene3D G3DSA:1.25.40.10 92 257 7.3E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Pfam PF13424 Tetratricopeptide repeat 825 894 5.6E-9 T 28-03-2018 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Pfam PF13424 Tetratricopeptide repeat 748 817 3.1E-7 T 28-03-2018 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SMART SM00862 11 83 1.9E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Pfam PF00486 Transcriptional regulatory protein, C terminal 18 71 6.9E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SUPERFAMILY SSF48452 668 775 3.04E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SUPERFAMILY SSF46894 2 71 2.83E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 PRINTS PR00364 Disease resistance protein signature 291 306 3.1E-9 T 28-03-2018 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 PRINTS PR00364 Disease resistance protein signature 368 382 3.1E-9 T 28-03-2018 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 PRINTS PR00364 Disease resistance protein signature 453 467 3.1E-9 T 28-03-2018 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Pfam PF00931 NB-ARC domain 274 476 2.1E-15 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Gene3D G3DSA:1.25.40.10 794 881 2.0E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SUPERFAMILY SSF48452 88 257 1.75E-35 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Gene3D G3DSA:1.10.10.10 2 91 8.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SMART SM00028 706 739 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SMART SM00028 826 859 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SMART SM00028 746 779 370.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SMART SM00028 786 819 44.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SMART SM00028 905 938 0.027 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 SMART SM00028 866 901 440.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Gene3D G3DSA:1.25.40.10 882 950 3.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Pfam PF03704 Bacterial transcriptional activator domain 90 234 2.0E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Gene3D G3DSA:3.40.50.300 258 412 2.9E-17 T 28-03-2018 SMD44_RS17885 a127a0155fa151457179c09b785af5e5 956 Gene3D G3DSA:1.10.150.200 743 793 3.4E-5 T 28-03-2018 SMD44_RS24470 708370c23f4f27dba19f8bf6a699123b 395 Pfam PF03583 Secretory lipase 127 392 1.5E-57 T 28-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD44_RS24470 708370c23f4f27dba19f8bf6a699123b 395 SUPERFAMILY SSF53474 84 231 7.76E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24470 708370c23f4f27dba19f8bf6a699123b 395 SUPERFAMILY SSF53474 287 383 7.76E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24470 708370c23f4f27dba19f8bf6a699123b 395 PIRSF PIRSF029171 1 395 1.9E-73 T 28-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD44_RS24470 708370c23f4f27dba19f8bf6a699123b 395 Gene3D G3DSA:3.40.50.1820 9 388 2.1E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 Gene3D G3DSA:2.10.109.10 67 263 3.7E-47 T 28-03-2018 SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 71 87 2.3E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 204 223 2.3E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 156 168 2.3E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 Pfam PF00717 Peptidase S24-like 78 120 7.1E-13 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 57 250 2.6E-40 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 SUPERFAMILY SSF51306 70 118 7.33E-50 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 SUPERFAMILY SSF51306 151 256 7.33E-50 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 Pfam PF10502 Signal peptidase, peptidase S26 147 244 6.2E-9 T 28-03-2018 IPR019533 Peptidase S26 SMD44_RS30505 14e3599133cb3289f2881a888ba4ee7f 360 ProSitePatterns PS00761 Signal peptidases I signature 3. 209 222 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 4.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 4.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 4.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 4.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 Pfam PF01047 MarR family 48 103 1.2E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 SMART SM00347 47 138 7.9E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 Gene3D G3DSA:1.10.10.10 6 159 3.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27110 074d0b1a79c72732b11e5f61c803addf 170 SUPERFAMILY SSF46785 38 152 5.96E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 Gene3D G3DSA:1.20.120.530 87 235 3.5E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 SMART SM00345 33 91 2.2E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 65 81 3.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 65 3.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 SMART SM00895 101 225 1.1E-14 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 Pfam PF07729 FCD domain 101 223 1.1E-21 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 Gene3D G3DSA:1.10.10.10 7 86 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 SUPERFAMILY SSF48008 97 229 7.59E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 SUPERFAMILY SSF46785 25 95 1.18E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21835 1ac6ffcf080147e949811774e5e7a2f4 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 91 2.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.1E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 271 286 2.1E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.1E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.1E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.1E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 315 2.3E-69 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 SUPERFAMILY SSF51735 2 152 3.64E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 SMART SM00846 3 153 4.0E-96 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 Gene3D G3DSA:3.40.50.720 1 162 2.0E-78 T 28-03-2018 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 Gene3D G3DSA:3.30.360.10 163 317 1.4E-67 T 28-03-2018 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 327 1.0E-138 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 104 7.4E-39 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 SUPERFAMILY SSF55347 153 316 1.22E-70 T 28-03-2018 SMD44_RS10125 51c735210539878e0d337d09bcdc9740 336 PIRSF PIRSF000149 1 334 6.5E-137 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS43370 1aef191d2eca4fec18e0b5aa2c0d4572 786 Gene3D G3DSA:3.40.50.300 310 647 2.0E-5 T 28-03-2018 SMD44_RS43370 1aef191d2eca4fec18e0b5aa2c0d4572 786 SUPERFAMILY SSF52540 270 680 2.77E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19315 55c65e4a44ff703cf0b39906345fddbc 247 Pfam PF00072 Response regulator receiver domain 11 121 2.0E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19315 55c65e4a44ff703cf0b39906345fddbc 247 SUPERFAMILY SSF52172 6 132 6.26E-46 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS19315 55c65e4a44ff703cf0b39906345fddbc 247 SMART SM00862 161 236 1.4E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19315 55c65e4a44ff703cf0b39906345fddbc 247 SUPERFAMILY SSF46894 138 237 1.28E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS19315 55c65e4a44ff703cf0b39906345fddbc 247 SMART SM00448 9 120 2.7E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19315 55c65e4a44ff703cf0b39906345fddbc 247 Gene3D G3DSA:3.40.50.2300 2 137 2.1E-43 T 28-03-2018 SMD44_RS19315 55c65e4a44ff703cf0b39906345fddbc 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 236 3.8E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19315 55c65e4a44ff703cf0b39906345fddbc 247 Gene3D G3DSA:1.10.10.10 138 243 1.5E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 351 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 326 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 370 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 298 312 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 Gene3D G3DSA:3.30.565.10 217 377 1.3E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 SMART SM00387 258 373 2.0E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 259 371 6.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 SMART SM00388 143 211 1.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 Gene3D G3DSA:3.30.450.20 11 135 1.5E-11 T 28-03-2018 SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 144 203 1.7E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 SUPERFAMILY SSF55785 14 121 6.28E-6 T 28-03-2018 IPR000014 PAS domain SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 Gene3D G3DSA:1.10.287.130 136 205 2.5E-14 T 28-03-2018 SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 SUPERFAMILY SSF55874 214 371 7.47E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14100 948cb53cb75668cebe79ca488c83e4f2 380 SUPERFAMILY SSF47384 129 204 5.3E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS26935 2e2af2c1e995736c3df90788fac76d54 145 SUPERFAMILY SSF110857 1 119 5.36E-13 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like SMD44_RS26935 2e2af2c1e995736c3df90788fac76d54 145 Pfam PF13772 AIG2-like family 59 140 1.7E-20 T 28-03-2018 SMD44_RS26935 2e2af2c1e995736c3df90788fac76d54 145 Gene3D G3DSA:3.10.490.10 1 144 2.9E-31 T 28-03-2018 SMD44_RS18115 d571d69174e9704747cf02bf3d288252 197 SUPERFAMILY SSF88946 10 94 3.37E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18115 d571d69174e9704747cf02bf3d288252 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 173 5.8E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18115 d571d69174e9704747cf02bf3d288252 197 Pfam PF04542 Sigma-70 region 2 28 94 3.7E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18115 d571d69174e9704747cf02bf3d288252 197 Gene3D G3DSA:1.10.10.10 125 180 1.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18115 d571d69174e9704747cf02bf3d288252 197 Gene3D G3DSA:1.10.1740.10 12 98 7.6E-15 T 28-03-2018 SMD44_RS18115 d571d69174e9704747cf02bf3d288252 197 SUPERFAMILY SSF88659 123 174 5.76E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16080 d6a4ae2ec760da8b40945abd50b74285 541 SMART SM00220 8 276 1.9E-75 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS16080 d6a4ae2ec760da8b40945abd50b74285 541 SUPERFAMILY SSF56112 395 458 2.98E-81 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS16080 d6a4ae2ec760da8b40945abd50b74285 541 SUPERFAMILY SSF56112 5 276 2.98E-81 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS16080 d6a4ae2ec760da8b40945abd50b74285 541 Gene3D G3DSA:3.30.200.20 2 114 5.5E-24 T 28-03-2018 SMD44_RS16080 d6a4ae2ec760da8b40945abd50b74285 541 Pfam PF00069 Protein kinase domain 10 269 1.6E-53 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS16080 d6a4ae2ec760da8b40945abd50b74285 541 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS16080 d6a4ae2ec760da8b40945abd50b74285 541 Gene3D G3DSA:1.10.510.10 115 449 1.7E-55 T 28-03-2018 SMD44_RS05535 d1598e59dc698c257a4c5b7b8ba1913c 310 SUPERFAMILY SSF103481 189 287 3.53E-11 T 28-03-2018 SMD44_RS05535 d1598e59dc698c257a4c5b7b8ba1913c 310 SUPERFAMILY SSF103481 40 140 9.55E-12 T 28-03-2018 SMD44_RS05535 d1598e59dc698c257a4c5b7b8ba1913c 310 Pfam PF00892 EamA-like transporter family 3 137 9.5E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS05535 d1598e59dc698c257a4c5b7b8ba1913c 310 Pfam PF00892 EamA-like transporter family 150 283 2.7E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS42440 c03d954be62aef16071fdd74044b83c3 365 Gene3D G3DSA:3.60.10.10 2 310 4.1E-28 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS42440 c03d954be62aef16071fdd74044b83c3 365 SUPERFAMILY SSF56219 27 310 2.88E-25 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS42440 c03d954be62aef16071fdd74044b83c3 365 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 33 302 8.8E-12 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS14450 bf253187d6dbf7545a4340e83999a67e 364 Gene3D G3DSA:2.30.30.60 172 220 7.3E-10 T 28-03-2018 SMD44_RS14450 bf253187d6dbf7545a4340e83999a67e 364 Gene3D G3DSA:3.30.70.100 221 315 3.6E-10 T 28-03-2018 SMD44_RS14450 bf253187d6dbf7545a4340e83999a67e 364 Pfam PF00924 Mechanosensitive ion channel 115 313 9.1E-35 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMD44_RS14450 bf253187d6dbf7545a4340e83999a67e 364 SUPERFAMILY SSF82689 221 313 3.66E-9 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SMD44_RS14450 bf253187d6dbf7545a4340e83999a67e 364 SUPERFAMILY SSF50182 157 214 1.28E-9 T 28-03-2018 IPR010920 LSM domain SMD44_RS14450 bf253187d6dbf7545a4340e83999a67e 364 SUPERFAMILY SSF82861 94 155 1.83E-8 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SMD44_RS23250 037d927c03419f114d7e5ccf75a45fdc 271 Gene3D G3DSA:1.10.3290.10 17 270 1.3E-26 T 28-03-2018 IPR003812 Fido domain SMD44_RS23250 037d927c03419f114d7e5ccf75a45fdc 271 SUPERFAMILY SSF140931 107 248 1.19E-5 T 28-03-2018 IPR003812 Fido domain SMD44_RS06635 64ea5ef67df58a73f1a58b6386995a9e 299 Gene3D G3DSA:1.20.5.1000 56 132 0.0013 T 28-03-2018 SMD44_RS06635 64ea5ef67df58a73f1a58b6386995a9e 299 Pfam PF05949 Bacterial protein of unknown function (DUF881) 140 288 3.3E-38 T 28-03-2018 IPR010273 Protein of unknown function DUF881 SMD44_RS08530 c33ac67b992fcf8dbc179987a1dbdf7d 441 Gene3D G3DSA:3.40.1660.10 30 170 8.7E-28 T 28-03-2018 SMD44_RS08530 c33ac67b992fcf8dbc179987a1dbdf7d 441 Gene3D G3DSA:3.40.1660.10 177 439 8.7E-29 T 28-03-2018 SMD44_RS08530 c33ac67b992fcf8dbc179987a1dbdf7d 441 Pfam PF05139 Erythromycin esterase 97 434 5.5E-77 T 28-03-2018 IPR007815 Erythromycin esterase GO:0046677 SMD44_RS08530 c33ac67b992fcf8dbc179987a1dbdf7d 441 SUPERFAMILY SSF159501 34 438 1.91E-106 T 28-03-2018 SMD44_RS08530 c33ac67b992fcf8dbc179987a1dbdf7d 441 PIRSF PIRSF036794 24 441 2.1E-117 T 28-03-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 268 278 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 SUPERFAMILY SSF52743 209 501 3.4E-84 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 444 454 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 Gene3D G3DSA:2.60.40.650 806 1106 4.8E-4 T 28-03-2018 SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 232 243 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 Gene3D G3DSA:3.40.50.200 198 501 6.1E-90 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 Gene3D G3DSA:2.60.40.10 503 615 2.3E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 Pfam PF00082 Subtilase family 227 492 8.8E-57 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 PRINTS PR00723 Subtilisin serine protease family (S8) signature 264 277 5.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 PRINTS PR00723 Subtilisin serine protease family (S8) signature 227 246 5.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 PRINTS PR00723 Subtilisin serine protease family (S8) signature 443 459 5.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS27040 6f8ea347042da78882b02efcfbab3721 1111 PIRSF PIRSF037854 3 1111 0.0 T 28-03-2018 IPR017297 Peptidase S8A, DPH-A SMD44_RS15845 3256d60cba4005e862666b7e02d043d9 284 Gene3D G3DSA:1.10.260.40 22 115 5.7E-11 T 28-03-2018 SMD44_RS15845 3256d60cba4005e862666b7e02d043d9 284 Pfam PF13560 Helix-turn-helix domain 27 82 9.1E-12 T 28-03-2018 SMD44_RS15845 3256d60cba4005e862666b7e02d043d9 284 SUPERFAMILY SSF47413 28 81 3.1E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS15845 3256d60cba4005e862666b7e02d043d9 284 SMART SM00530 31 86 0.0036 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS18705 6cd83ce279342608cdabc4addfd48efd 407 Pfam PF07690 Major Facilitator Superfamily 10 331 1.2E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS18705 6cd83ce279342608cdabc4addfd48efd 407 SUPERFAMILY SSF103473 4 377 2.62E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS18705 6cd83ce279342608cdabc4addfd48efd 407 Gene3D G3DSA:1.20.1250.20 194 383 1.5E-13 T 28-03-2018 SMD44_RS18705 6cd83ce279342608cdabc4addfd48efd 407 Gene3D G3DSA:1.20.1250.20 3 188 2.2E-25 T 28-03-2018 SMD44_RS12370 201355f528f9ccff5c77a9cfc1f40ab4 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS12370 201355f528f9ccff5c77a9cfc1f40ab4 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS12370 201355f528f9ccff5c77a9cfc1f40ab4 211 SUPERFAMILY SSF46689 18 102 1.2E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS12370 201355f528f9ccff5c77a9cfc1f40ab4 211 Gene3D G3DSA:1.10.357.10 7 203 7.7E-31 T 28-03-2018 SMD44_RS12370 201355f528f9ccff5c77a9cfc1f40ab4 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 76 1.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19610 aac92f9c8c4d5e881d613291a68a1806 351 Pfam PF01551 Peptidase family M23 245 340 2.8E-27 T 28-03-2018 IPR016047 Peptidase M23 SMD44_RS19610 aac92f9c8c4d5e881d613291a68a1806 351 Gene3D G3DSA:2.70.70.10 213 346 5.2E-40 T 28-03-2018 SMD44_RS19610 aac92f9c8c4d5e881d613291a68a1806 351 Gene3D G3DSA:3.40.50.300 25 212 4.5E-5 T 28-03-2018 SMD44_RS19610 aac92f9c8c4d5e881d613291a68a1806 351 SUPERFAMILY SSF51261 148 344 8.37E-44 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS37990 b1c0d894d79194c0520cd4cb55b5f219 352 SUPERFAMILY SSF56112 14 304 2.84E-21 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS37990 b1c0d894d79194c0520cd4cb55b5f219 352 Pfam PF00069 Protein kinase domain 138 298 5.6E-8 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS37990 b1c0d894d79194c0520cd4cb55b5f219 352 SMART SM00220 15 309 4.2E-4 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS37990 b1c0d894d79194c0520cd4cb55b5f219 352 Gene3D G3DSA:1.10.510.10 9 309 1.1E-21 T 28-03-2018 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Pfam PF08659 KR domain 1061 1238 2.2E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 213 330 3.1E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Pfam PF00698 Acyl transferase domain 367 683 1.4E-58 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Gene3D G3DSA:3.40.50.720 1053 1313 2.7E-56 T 28-03-2018 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1379 1394 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF55048 490 554 1.96E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF52151 364 491 2.3E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF52151 555 649 2.3E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Gene3D G3DSA:3.40.47.10 1 98 4.1E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Gene3D G3DSA:3.30.70.250 503 546 2.6E-17 T 28-03-2018 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF53901 53 264 1.88E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SMART SM00823 Phosphopantetheine attachment site 1352 1424 1.1E-30 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 93 210 2.0E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Gene3D G3DSA:3.40.366.10 547 669 8.8E-27 T 28-03-2018 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF51735 777 973 1.85E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF51735 1005 1048 1.85E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SMART SM00825 Beta-ketoacyl synthase 1 265 1.1E-91 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF51735 1057 1290 3.64E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Gene3D G3DSA:3.40.366.10 363 502 3.2E-47 T 28-03-2018 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 85 6.1E-32 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF47336 1345 1429 1.57E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1061 1240 1.5E-53 T 28-03-2018 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Pfam PF00550 Phosphopantetheine attachment site 1355 1417 3.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SUPERFAMILY SSF53901 1 56 2.26E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Gene3D G3DSA:1.10.1200.10 1344 1460 2.1E-19 T 28-03-2018 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 Gene3D G3DSA:3.40.47.10 100 263 7.9E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 367 664 4.7E-122 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36810 e3712243b8526deb461566647c7e4094 1512 SMART SM01294 1353 1420 3.1E-6 T 28-03-2018 SMD44_RS06060 f3bbbad146247fb092afe9ae52e059fa 300 Gene3D G3DSA:3.40.50.720 5 168 3.5E-26 T 28-03-2018 SMD44_RS06060 f3bbbad146247fb092afe9ae52e059fa 300 PIRSF PIRSF000103 1 295 2.0E-65 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS06060 f3bbbad146247fb092afe9ae52e059fa 300 SUPERFAMILY SSF51735 4 162 9.44E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS06060 f3bbbad146247fb092afe9ae52e059fa 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 161 4.1E-29 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS06060 f3bbbad146247fb092afe9ae52e059fa 300 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 285 1.6E-16 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMD44_RS06060 f3bbbad146247fb092afe9ae52e059fa 300 Gene3D G3DSA:1.10.1040.10 169 295 1.4E-27 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS06060 f3bbbad146247fb092afe9ae52e059fa 300 SUPERFAMILY SSF48179 166 289 4.08E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 SUPERFAMILY SSF52540 16 242 9.87E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 SUPERFAMILY SSF52540 283 491 9.73E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 Pfam PF00005 ABC transporter 34 183 2.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 Pfam PF00005 ABC transporter 285 439 1.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 ProSitePatterns PS00211 ABC transporters family signature. 411 425 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 SMART SM00382 42 245 9.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 SMART SM00382 293 486 0.11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 Gene3D G3DSA:3.40.50.300 262 494 1.4E-37 T 28-03-2018 SMD44_RS37180 3cf02452def106525393bf6ec786eb33 544 Gene3D G3DSA:3.40.50.300 17 261 2.4E-45 T 28-03-2018 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 2.3E-47 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 Gene3D G3DSA:3.40.47.10 277 403 3.6E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 SUPERFAMILY SSF53901 3 278 1.15E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 Pfam PF00108 Thiolase, N-terminal domain 7 230 4.0E-45 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 Gene3D G3DSA:3.40.47.10 1 276 1.3E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 SUPERFAMILY SSF53901 283 403 5.19E-46 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 PIRSF PIRSF000429 1 404 4.8E-112 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD44_RS35345 9c970fa9e659f2e854111bd34bd0a0fb 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 402 9.8E-138 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 Hamap MF_00743 Fumarate hydratase class II [fumC]. 20 477 82.004 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 PRINTS PR00149 Fumarate lyase superfamily signature 327 343 1.0E-32 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 PRINTS PR00149 Fumarate lyase superfamily signature 281 308 1.0E-32 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 PRINTS PR00149 Fumarate lyase superfamily signature 144 162 1.0E-32 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 PRINTS PR00149 Fumarate lyase superfamily signature 190 208 1.0E-32 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 Gene3D G3DSA:1.10.275.10 19 148 1.8E-53 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 SUPERFAMILY SSF48557 20 476 1.48E-144 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 Pfam PF10415 Fumarase C C-terminus 418 476 1.3E-20 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 ProSitePatterns PS00163 Fumarate lyases signature. 327 336 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 Pfam PF00206 Lyase 28 352 1.3E-102 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 Gene3D G3DSA:1.20.200.10 149 427 8.3E-81 T 28-03-2018 SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 PRINTS PR00145 Argininosuccinate lyase family signature 327 343 3.8E-6 T 28-03-2018 SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 PRINTS PR00145 Argininosuccinate lyase family signature 185 205 3.8E-6 T 28-03-2018 SMD44_RS27495 7d0878fc1f20cca55cd6b5f38fd886ca 477 Gene3D G3DSA:1.10.40.30 428 477 1.1E-24 T 28-03-2018 SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.1E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.1E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.1E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.1E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.1E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 181 5.1E-9 T 28-03-2018 SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 Gene3D G3DSA:3.40.50.720 151 236 9.4E-26 T 28-03-2018 SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 6.2E-65 T 28-03-2018 SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 Gene3D G3DSA:3.40.50.720 2 150 2.0E-50 T 28-03-2018 SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 235 5.3E-97 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 SUPERFAMILY SSF51735 3 235 5.92E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09370 435b4a11f7e5d574109985854488aef2 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS23685 54805ba358499c75136b7a3a99ace8ba 374 Pfam PF10103 Zincin-like metallopeptidase 10 366 5.0E-122 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 SMD44_RS23685 54805ba358499c75136b7a3a99ace8ba 374 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 10 370 1.7E-143 T 28-03-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated SMD44_RS23685 54805ba358499c75136b7a3a99ace8ba 374 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 10 370 4.1E-126 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 SMD44_RS23685 54805ba358499c75136b7a3a99ace8ba 374 SUPERFAMILY SSF55486 9 369 1.76E-107 T 28-03-2018 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 168 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 PIRSF PIRSF001365 2 310 1.3E-68 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 Pfam PF00701 Dihydrodipicolinate synthetase family 7 306 6.3E-43 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 SMART SM01130 6 308 8.6E-75 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 Gene3D G3DSA:3.20.20.70 1 310 1.4E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.7E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 1.7E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 1.7E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS13660 386277a0a9ffdca1117e35ccbb4cde5e 310 SUPERFAMILY SSF51569 2 310 6.7E-73 T 28-03-2018 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 Pfam PF00067 Cytochrome P450 295 386 5.1E-18 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 Gene3D G3DSA:1.10.630.10 33 420 1.4E-73 T 28-03-2018 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 365 374 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 TIGRFAM TIGR04515 P450_rel_GT_act: P450-derived glycosyltranferase activator 18 419 2.2E-103 T 28-03-2018 IPR030958 P450-derived glycosyltranferase activator SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 216 238 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 173 188 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 341 356 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 372 383 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 110 121 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 156 172 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 313 340 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 363 372 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 PRINTS PR00359 B-class P450 signature 296 307 7.4E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36915 5fdae00cc78a33e04c760a109168e011 423 SUPERFAMILY SSF48264 31 421 4.58E-90 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 Gene3D G3DSA:1.10.10.60 231 268 5.0E-14 T 28-03-2018 SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 SUPERFAMILY SSF46689 214 262 4.21E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 SUPERFAMILY SSF46689 265 315 2.64E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 Gene3D G3DSA:3.40.50.880 2 230 2.1E-64 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 Pfam PF01965 DJ-1/PfpI family 5 173 5.9E-18 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 SMART SM00342 228 311 2.4E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 Gene3D G3DSA:1.10.10.60 269 321 2.5E-12 T 28-03-2018 SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 Pfam PF12833 Helix-turn-helix domain 234 312 9.8E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS28305 182621ee535abcb8df38530e4cfeded2 323 SUPERFAMILY SSF52317 4 194 9.48E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 SUPERFAMILY SSF52172 3 123 1.71E-12 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 7.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 7.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 7.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 SUPERFAMILY SSF46894 140 217 5.1E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 SMART SM00421 153 210 2.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 Gene3D G3DSA:1.10.10.10 128 220 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 Gene3D G3DSA:3.40.50.2300 2 127 8.4E-16 T 28-03-2018 SMD44_RS17035 cae474e3696b7aca568c71334982cc4c 241 Pfam PF00072 Response regulator receiver domain 6 105 1.2E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS06725 08abb04d6635ef4d47677e7489ec1d85 201 Gene3D G3DSA:3.40.50.300 7 191 3.2E-18 T 28-03-2018 SMD44_RS06725 08abb04d6635ef4d47677e7489ec1d85 201 Pfam PF03029 Conserved hypothetical ATP binding protein 22 189 7.3E-27 T 28-03-2018 IPR004130 GPN-loop GTPase SMD44_RS06725 08abb04d6635ef4d47677e7489ec1d85 201 SUPERFAMILY SSF52540 15 189 1.39E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31190 7e74abcd66129c4462e9bd6e024587d8 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 97 3.6E-10 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 SMART SM01043 95 236 1.8E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 Gene3D G3DSA:1.25.40.10 97 285 3.6E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 Gene3D G3DSA:3.40.50.300 322 471 3.9E-11 T 28-03-2018 SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 Pfam PF03704 Bacterial transcriptional activator domain 95 236 9.9E-40 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 SUPERFAMILY SSF52540 322 586 8.46E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 Gene3D G3DSA:1.10.10.10 2 96 8.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 SMART SM00862 16 88 2.5E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 Gene3D G3DSA:1.25.40.10 843 1143 2.9E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 SUPERFAMILY SSF46894 11 88 2.49E-9 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 78 7.9E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 SUPERFAMILY SSF48452 91 248 8.67E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19575 99658e1cecc0d99b6c9766b38c4ab730 1165 SUPERFAMILY SSF48452 907 1032 2.54E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS39390 612d338c682e70fb355722cc286ba69a 137 SUPERFAMILY SSF103196 5 124 4.97E-35 T 28-03-2018 SMD44_RS39390 612d338c682e70fb355722cc286ba69a 137 Pfam PF03259 Roadblock/LC7 domain 8 97 4.5E-27 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS39390 612d338c682e70fb355722cc286ba69a 137 SMART SM00960 8 98 1.4E-31 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS39390 612d338c682e70fb355722cc286ba69a 137 Gene3D G3DSA:3.30.450.30 3 130 1.5E-42 T 28-03-2018 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 SMART SM00631 128 419 2.4E-101 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 179 193 1.1E-10 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 154 166 1.1E-10 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 320 333 1.1E-10 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 261 269 1.1E-10 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 179 201 - T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 Pfam PF00246 Zinc carboxypeptidase 135 422 3.2E-70 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 Gene3D G3DSA:3.40.630.10 124 434 8.1E-71 T 28-03-2018 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 323 333 - T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS27320 ce246650dd1952a37be6874afa5841c8 449 SUPERFAMILY SSF53187 125 431 1.22E-81 T 28-03-2018 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 Gene3D G3DSA:2.30.38.10 381 462 8.4E-23 T 28-03-2018 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 Gene3D G3DSA:3.40.50.980 210 375 3.2E-36 T 28-03-2018 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 80 493 2.6E-129 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 Pfam PF08242 Methyltransferase domain 599 698 1.2E-12 T 28-03-2018 IPR013217 Methyltransferase type 12 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 Gene3D G3DSA:3.40.50.980 49 209 1.7E-41 T 28-03-2018 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 Pfam PF00501 AMP-binding enzyme 58 469 1.8E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 Gene3D G3DSA:3.40.50.150 552 769 1.2E-30 T 28-03-2018 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 SUPERFAMILY SSF56801 47 520 1.44E-131 T 28-03-2018 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 Gene3D G3DSA:3.30.300.30 463 544 7.8E-20 T 28-03-2018 SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 Pfam PF13193 AMP-binding enzyme C-terminal domain 477 534 2.5E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS39795 8ac992d76db3d090670bc196ad6cbe79 778 SUPERFAMILY SSF53335 560 704 1.69E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS11925 28027ab72e47d43278b55359a5f2407b 244 Pfam PF06197 Protein of unknown function (DUF998) 23 235 1.4E-23 T 28-03-2018 IPR009339 Protein of unknown function DUF998 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 PRINTS PR00143 Citrate synthase signature 263 291 3.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 PRINTS PR00143 Citrate synthase signature 402 416 3.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 PRINTS PR00143 Citrate synthase signature 382 398 3.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 PRINTS PR00143 Citrate synthase signature 241 256 3.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 PRINTS PR00143 Citrate synthase signature 319 339 3.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 PRINTS PR00143 Citrate synthase signature 187 200 3.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 Pfam PF00285 Citrate synthase, C-terminal domain 68 434 1.0E-135 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 ProSitePatterns PS00480 Citrate synthase signature. 326 338 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 SUPERFAMILY SSF48256 25 451 6.28E-160 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 Gene3D G3DSA:1.10.230.10 305 402 1.5E-33 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 36 445 5.8E-183 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 PIRSF PIRSF001369 59 451 3.9E-156 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type SMD44_RS14760 d1bc68bffe1c751d74c47226274e10be 451 Gene3D G3DSA:1.10.580.10 52 304 3.1E-90 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 Pfam PF12697 Alpha/beta hydrolase family 42 274 7.1E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 PRINTS PR00412 Epoxide hydrolase signature 122 135 3.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 PRINTS PR00412 Epoxide hydrolase signature 65 80 3.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 PRINTS PR00412 Epoxide hydrolase signature 258 280 3.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 6.1E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 227 241 6.1E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 6.1E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 6.1E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 Gene3D G3DSA:3.40.50.1820 11 283 1.2E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38035 5d8b3ade9c238b982f4229c3f8a6d56a 283 SUPERFAMILY SSF53474 15 282 7.18E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27015 9936ef47439a3bb3a829be05e386d337 512 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 506 2.7E-213 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS27015 9936ef47439a3bb3a829be05e386d337 512 SUPERFAMILY SSF48557 3 505 1.26E-176 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMD44_RS27015 9936ef47439a3bb3a829be05e386d337 512 Gene3D G3DSA:1.20.200.10 199 510 5.4E-112 T 28-03-2018 SMD44_RS27015 9936ef47439a3bb3a829be05e386d337 512 Gene3D G3DSA:1.10.275.10 2 198 8.1E-73 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SMD44_RS27015 9936ef47439a3bb3a829be05e386d337 512 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 SMD44_RS27015 9936ef47439a3bb3a829be05e386d337 512 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 506 43.306 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS27015 9936ef47439a3bb3a829be05e386d337 512 Pfam PF00221 Aromatic amino acid lyase 12 472 9.9E-180 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SMD44_RS08210 37e3b9ed32ec1628dc1ff6edd791c248 535 Gene3D G3DSA:3.90.76.10 48 194 1.0E-30 T 28-03-2018 SMD44_RS08210 37e3b9ed32ec1628dc1ff6edd791c248 535 Gene3D G3DSA:3.10.105.10 297 502 1.8E-45 T 28-03-2018 SMD44_RS08210 37e3b9ed32ec1628dc1ff6edd791c248 535 PIRSF PIRSF002741 1 530 3.8E-78 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS08210 37e3b9ed32ec1628dc1ff6edd791c248 535 SUPERFAMILY SSF53850 47 528 2.1E-99 T 28-03-2018 SMD44_RS08210 37e3b9ed32ec1628dc1ff6edd791c248 535 Gene3D G3DSA:3.40.190.10 195 296 2.4E-17 T 28-03-2018 SMD44_RS08210 37e3b9ed32ec1628dc1ff6edd791c248 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 450 7.6E-76 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS13785 506ccad5d49e8c04dcdd611d50672a4a 249 Gene3D G3DSA:2.40.240.20 1 72 2.1E-16 T 28-03-2018 SMD44_RS13785 506ccad5d49e8c04dcdd611d50672a4a 249 SUPERFAMILY SSF75217 81 248 1.1E-45 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SMD44_RS13785 506ccad5d49e8c04dcdd611d50672a4a 249 PIRSF PIRSF015601 4 248 5.0E-44 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS13785 506ccad5d49e8c04dcdd611d50672a4a 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 21 241 5.5E-31 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS13785 506ccad5d49e8c04dcdd611d50672a4a 249 SUPERFAMILY SSF88697 5 66 4.22E-9 T 28-03-2018 IPR015947 PUA-like domain SMD44_RS13785 506ccad5d49e8c04dcdd611d50672a4a 249 Gene3D G3DSA:3.40.1280.10 78 249 7.9E-53 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD44_RS13785 506ccad5d49e8c04dcdd611d50672a4a 249 Pfam PF04452 RNA methyltransferase 22 241 1.2E-59 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD44_RS35915 788a7d0504d03bbf841dbf43007c245b 563 Pfam PF00239 Resolvase, N terminal domain 77 220 8.5E-19 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS35915 788a7d0504d03bbf841dbf43007c245b 563 Pfam PF07508 Recombinase 245 348 8.9E-14 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 SMD44_RS35915 788a7d0504d03bbf841dbf43007c245b 563 SUPERFAMILY SSF53041 83 216 2.22E-18 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS35915 788a7d0504d03bbf841dbf43007c245b 563 Gene3D G3DSA:3.40.50.1390 68 231 2.3E-25 T 28-03-2018 SMD44_RS35915 788a7d0504d03bbf841dbf43007c245b 563 SMART SM00857 73 221 1.1E-17 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS06015 82a2d698cc6e90c3ca5542ee8fa9e007 318 SMART SM00382 28 206 1.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS06015 82a2d698cc6e90c3ca5542ee8fa9e007 318 Pfam PF00005 ABC transporter 20 158 8.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS06015 82a2d698cc6e90c3ca5542ee8fa9e007 318 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS06015 82a2d698cc6e90c3ca5542ee8fa9e007 318 SUPERFAMILY SSF52540 4 226 1.45E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS06015 82a2d698cc6e90c3ca5542ee8fa9e007 318 Gene3D G3DSA:3.40.50.300 1 301 2.2E-59 T 28-03-2018 SMD44_RS11365 8015db48ad6da6c91721ee6be094b69a 354 Gene3D G3DSA:1.20.970.10 11 84 8.2E-23 T 28-03-2018 SMD44_RS11365 8015db48ad6da6c91721ee6be094b69a 354 Gene3D G3DSA:3.40.1030.10 85 354 1.9E-102 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS11365 8015db48ad6da6c91721ee6be094b69a 354 Pfam PF00591 Glycosyl transferase family, a/b domain 89 341 8.7E-82 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS11365 8015db48ad6da6c91721ee6be094b69a 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 19 351 35.417 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SMD44_RS11365 8015db48ad6da6c91721ee6be094b69a 354 SUPERFAMILY SSF47648 17 84 2.62E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS11365 8015db48ad6da6c91721ee6be094b69a 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 19 80 9.0E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS11365 8015db48ad6da6c91721ee6be094b69a 354 SUPERFAMILY SSF52418 87 353 4.32E-83 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS11365 8015db48ad6da6c91721ee6be094b69a 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 23 350 3.0E-109 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SMD44_RS06115 037f32f2bd8d5d04a55aa4c3117a6744 339 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 36 59 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS06115 037f32f2bd8d5d04a55aa4c3117a6744 339 PIRSF PIRSF000654 8 287 2.8E-25 T 28-03-2018 SMD44_RS06115 037f32f2bd8d5d04a55aa4c3117a6744 339 Gene3D G3DSA:1.10.510.10 99 281 6.6E-48 T 28-03-2018 SMD44_RS06115 037f32f2bd8d5d04a55aa4c3117a6744 339 Pfam PF00069 Protein kinase domain 30 246 8.5E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS06115 037f32f2bd8d5d04a55aa4c3117a6744 339 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 149 161 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS06115 037f32f2bd8d5d04a55aa4c3117a6744 339 Gene3D G3DSA:3.30.200.20 7 98 2.3E-17 T 28-03-2018 SMD44_RS06115 037f32f2bd8d5d04a55aa4c3117a6744 339 SUPERFAMILY SSF56112 28 294 2.56E-70 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS06115 037f32f2bd8d5d04a55aa4c3117a6744 339 SMART SM00220 30 297 1.7E-59 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS41350 eed1aabe34d653ef8a48e7e288aae94c 159 Gene3D G3DSA:3.90.1200.10 7 132 4.3E-7 T 28-03-2018 SMD44_RS41350 eed1aabe34d653ef8a48e7e288aae94c 159 SUPERFAMILY SSF56112 7 113 7.55E-8 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS41350 eed1aabe34d653ef8a48e7e288aae94c 159 Pfam PF01636 Phosphotransferase enzyme family 2 112 2.5E-5 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS09315 6038a4462e7a8773687b7883a0aabed6 230 Gene3D G3DSA:1.10.530.10 78 230 4.9E-22 T 28-03-2018 SMD44_RS09315 6038a4462e7a8773687b7883a0aabed6 230 SUPERFAMILY SSF53955 137 224 5.38E-15 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS09315 6038a4462e7a8773687b7883a0aabed6 230 Pfam PF01464 Transglycosylase SLT domain 155 227 2.1E-10 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SMD44_RS24550 3c6bda09444ee4c5fb0dcc7f66246212 376 SMART SM00382 48 237 1.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS24550 3c6bda09444ee4c5fb0dcc7f66246212 376 Gene3D G3DSA:3.40.50.300 18 329 2.1E-67 T 28-03-2018 SMD44_RS24550 3c6bda09444ee4c5fb0dcc7f66246212 376 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 322 6.3E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS24550 3c6bda09444ee4c5fb0dcc7f66246212 376 Pfam PF00005 ABC transporter 39 188 3.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS24550 3c6bda09444ee4c5fb0dcc7f66246212 376 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 2.0E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS24550 3c6bda09444ee4c5fb0dcc7f66246212 376 SUPERFAMILY SSF52540 11 264 4.54E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS24550 3c6bda09444ee4c5fb0dcc7f66246212 376 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS02545 a096de79e3a4682ab5938e282d974f02 247 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS02545 a096de79e3a4682ab5938e282d974f02 247 SMART SM00382 28 208 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS02545 a096de79e3a4682ab5938e282d974f02 247 Gene3D G3DSA:3.40.50.300 1 235 2.7E-56 T 28-03-2018 SMD44_RS02545 a096de79e3a4682ab5938e282d974f02 247 SUPERFAMILY SSF52540 3 220 6.48E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS02545 a096de79e3a4682ab5938e282d974f02 247 Pfam PF00005 ABC transporter 22 161 3.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS39400 1fa9dfffb331af7e1f2f9f0fc2fe918f 177 Gene3D G3DSA:1.25.40.10 3 103 1.7E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS39400 1fa9dfffb331af7e1f2f9f0fc2fe918f 177 Pfam PF12688 Tetratrico peptide repeat 53 172 2.1E-15 T 28-03-2018 SMD44_RS39400 1fa9dfffb331af7e1f2f9f0fc2fe918f 177 Gene3D G3DSA:1.25.40.10 104 160 6.0E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS39400 1fa9dfffb331af7e1f2f9f0fc2fe918f 177 SUPERFAMILY SSF48452 21 171 3.56E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23460 175ff266a8be03770d110df3416be45b 437 Gene3D G3DSA:3.30.565.10 302 435 2.4E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23460 175ff266a8be03770d110df3416be45b 437 SUPERFAMILY SSF55874 313 426 2.19E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23460 175ff266a8be03770d110df3416be45b 437 Pfam PF07730 Histidine kinase 241 305 1.2E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS23460 175ff266a8be03770d110df3416be45b 437 Pfam PF13796 Putative sensor 44 210 1.3E-7 T 28-03-2018 IPR025828 Putative sensor domain SMD44_RS06095 4aec6abea3deef55d9b996441aaadc2b 1077 SUPERFAMILY SSF52540 1 105 6.28E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS06095 4aec6abea3deef55d9b996441aaadc2b 1077 SUPERFAMILY SSF52540 205 264 6.28E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS06095 4aec6abea3deef55d9b996441aaadc2b 1077 SUPERFAMILY SSF52540 853 1071 6.28E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS06095 4aec6abea3deef55d9b996441aaadc2b 1077 Gene3D G3DSA:3.40.50.300 1 310 4.4E-27 T 28-03-2018 SMD44_RS06095 4aec6abea3deef55d9b996441aaadc2b 1077 Gene3D G3DSA:3.40.50.300 723 1072 1.0E-11 T 28-03-2018 SMD44_RS06095 4aec6abea3deef55d9b996441aaadc2b 1077 Pfam PF13476 AAA domain 5 120 7.8E-20 T 28-03-2018 SMD44_RS06095 4aec6abea3deef55d9b996441aaadc2b 1077 Pfam PF13558 Putative exonuclease SbcCD, C subunit 969 1034 1.5E-12 T 28-03-2018 SMD44_RS35615 5e28ec99961506338c8a6e86e18ffa8b 177 Pfam PF00293 NUDIX domain 40 151 6.6E-21 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS35615 5e28ec99961506338c8a6e86e18ffa8b 177 Gene3D G3DSA:3.90.79.10 1 176 3.9E-38 T 28-03-2018 SMD44_RS35615 5e28ec99961506338c8a6e86e18ffa8b 177 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS35615 5e28ec99961506338c8a6e86e18ffa8b 177 SUPERFAMILY SSF55811 2 171 1.12E-39 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS35615 5e28ec99961506338c8a6e86e18ffa8b 177 PRINTS PR00502 NUDIX hydrolase family signature 83 98 3.7E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS35615 5e28ec99961506338c8a6e86e18ffa8b 177 PRINTS PR00502 NUDIX hydrolase family signature 69 83 3.7E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS24410 19429fc04f45692693a6ed900de8143c 301 Pfam PF01040 UbiA prenyltransferase family 37 278 2.7E-52 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMD44_RS24410 19429fc04f45692693a6ed900de8143c 301 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 16 295 4.0E-89 T 28-03-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related SMD44_RS06315 c3be91658ac4252021c2270c242d5991 155 Gene3D G3DSA:3.10.129.10 5 155 8.7E-16 T 28-03-2018 SMD44_RS06315 c3be91658ac4252021c2270c242d5991 155 SUPERFAMILY SSF54637 12 153 7.84E-16 T 28-03-2018 IPR029069 HotDog domain SMD44_RS06315 c3be91658ac4252021c2270c242d5991 155 Pfam PF14539 Domain of unknown function (DUF4442) 13 148 1.3E-22 T 28-03-2018 IPR027961 Protein of unknown function DUF4442 SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 159 181 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 SUPERFAMILY SSF55021 178 276 6.11E-24 T 28-03-2018 SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 Pfam PF00800 Prephenate dehydratase 8 184 6.4E-47 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 Gene3D G3DSA:3.40.190.10 2 97 3.1E-28 T 28-03-2018 SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 Gene3D G3DSA:3.40.190.10 98 166 5.2E-22 T 28-03-2018 SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 Pfam PF01842 ACT domain 198 259 1.3E-7 T 28-03-2018 IPR002912 ACT domain SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 Gene3D G3DSA:3.30.70.260 188 282 2.7E-29 T 28-03-2018 SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 SUPERFAMILY SSF53850 5 188 2.82E-50 T 28-03-2018 SMD44_RS20725 e36f6332edd7e0a91e25e0db8e208747 311 PIRSF PIRSF001500 2 279 1.0E-59 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SMD44_RS43435 bb72bf415f19419b749149e25019469c 206 SMART SM00866 51 189 0.0031 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS43435 bb72bf415f19419b749149e25019469c 206 SUPERFAMILY SSF64288 61 190 1.88E-13 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS43435 bb72bf415f19419b749149e25019469c 206 Gene3D G3DSA:3.40.1410.10 56 195 1.6E-15 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS43435 bb72bf415f19419b749149e25019469c 206 Pfam PF07702 UTRA domain 64 188 1.3E-8 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS02255 66b44273905998b625ffcf9d2addf639 260 Pfam PF01909 Nucleotidyltransferase domain 22 56 3.2E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 SMD44_RS02255 66b44273905998b625ffcf9d2addf639 260 SUPERFAMILY SSF81301 15 89 1.13E-8 T 28-03-2018 SMD44_RS02255 66b44273905998b625ffcf9d2addf639 260 Gene3D G3DSA:3.30.460.10 3 125 3.1E-10 T 28-03-2018 SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 SUPERFAMILY SSF51735 122 244 5.78E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 Gene3D G3DSA:3.40.50.720 66 246 1.6E-8 T 28-03-2018 SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 SUPERFAMILY SSF51735 270 516 1.88E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 397 413 7.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 276 293 7.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 445 462 7.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 478 498 7.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 424 443 7.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 350 361 7.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 Gene3D G3DSA:3.40.50.720 253 517 4.7E-57 T 28-03-2018 SMD44_RS01900 9364307590ca4a4b528324f7b3ecd8ff 536 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 281 514 4.4E-42 T 28-03-2018 SMD44_RS19300 64ba86babf48d7b5af79991493705685 284 SUPERFAMILY SSF46894 126 221 2.01E-29 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS19300 64ba86babf48d7b5af79991493705685 284 Gene3D G3DSA:1.10.10.10 111 226 1.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19300 64ba86babf48d7b5af79991493705685 284 SMART SM00862 145 219 4.1E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19300 64ba86babf48d7b5af79991493705685 284 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 2.5E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS31010 0f0a1e0ca1842e006af26de0c0f8ed17 70 Pfam PF05593 RHS Repeat 22 59 7.0E-8 T 28-03-2018 IPR031325 RHS repeat SMD44_RS31010 0f0a1e0ca1842e006af26de0c0f8ed17 70 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 22 53 2.7E-9 T 28-03-2018 IPR006530 YD repeat SMD44_RS31010 0f0a1e0ca1842e006af26de0c0f8ed17 70 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 15 36 4.8E-5 T 28-03-2018 IPR006530 YD repeat SMD44_RS13480 ffbabfad7f2c53d9a41af9315fbdc888 423 Pfam PF00480 ROK family 96 405 7.1E-40 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS13480 ffbabfad7f2c53d9a41af9315fbdc888 423 SUPERFAMILY SSF46785 19 80 6.48E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13480 ffbabfad7f2c53d9a41af9315fbdc888 423 ProSitePatterns PS01125 ROK family signature. 240 267 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS13480 ffbabfad7f2c53d9a41af9315fbdc888 423 SUPERFAMILY SSF53067 87 407 1.1E-46 T 28-03-2018 SMD44_RS13480 ffbabfad7f2c53d9a41af9315fbdc888 423 Gene3D G3DSA:1.10.10.10 10 78 2.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13480 ffbabfad7f2c53d9a41af9315fbdc888 423 Gene3D G3DSA:3.30.420.40 79 229 1.9E-30 T 28-03-2018 SMD44_RS13480 ffbabfad7f2c53d9a41af9315fbdc888 423 Gene3D G3DSA:3.30.420.40 230 412 9.7E-46 T 28-03-2018 SMD44_RS40195 b508c98901a04360fd0f4c80d85cbc6f 676 Gene3D G3DSA:3.20.20.80 308 594 7.3E-21 T 28-03-2018 SMD44_RS40195 b508c98901a04360fd0f4c80d85cbc6f 676 SUPERFAMILY SSF51445 302 596 2.02E-27 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS40195 b508c98901a04360fd0f4c80d85cbc6f 676 Gene3D G3DSA:2.60.120.260 33 194 1.5E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS19445 739686dd6d1c3a866bf2a63a126ff6d4 281 Pfam PF13560 Helix-turn-helix domain 11 71 1.8E-14 T 28-03-2018 SMD44_RS19445 739686dd6d1c3a866bf2a63a126ff6d4 281 SUPERFAMILY SSF47413 11 70 2.56E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS19445 739686dd6d1c3a866bf2a63a126ff6d4 281 SMART SM00530 15 70 3.9E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS19445 739686dd6d1c3a866bf2a63a126ff6d4 281 Gene3D G3DSA:1.10.260.40 3 83 9.1E-14 T 28-03-2018 SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 SMART SM00344 3 110 3.7E-27 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 SUPERFAMILY SSF46785 2 63 3.52E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 Gene3D G3DSA:1.10.10.10 1 54 4.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 Gene3D G3DSA:3.30.70.920 56 137 3.5E-18 T 28-03-2018 SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 7.7E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 SUPERFAMILY SSF54909 65 143 3.49E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.7E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.7E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.7E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD44_RS07090 70fdfc5193023b43f899796d69e1d020 151 Pfam PF01037 Lrp/AsnC ligand binding domain 69 139 9.5E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS21115 a2168cab402ab020e85b2787c60ace4a 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 4.0E-13 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS21115 a2168cab402ab020e85b2787c60ace4a 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.729 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS21115 a2168cab402ab020e85b2787c60ace4a 45 Pfam PF00468 Ribosomal protein L34 3 45 1.5E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS21115 a2168cab402ab020e85b2787c60ace4a 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS21115 a2168cab402ab020e85b2787c60ace4a 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 2.6E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 Pfam PF00067 Cytochrome P450 229 365 3.6E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00359 B-class P450 signature 271 282 1.6E-12 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00359 B-class P450 signature 348 359 1.6E-12 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00359 B-class P450 signature 88 99 1.6E-12 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00359 B-class P450 signature 288 315 1.6E-12 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00359 B-class P450 signature 339 348 1.6E-12 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 SUPERFAMILY SSF48264 16 398 4.06E-64 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 Gene3D G3DSA:1.10.630.10 3 399 6.8E-55 T 28-03-2018 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00385 P450 superfamily signature 339 348 6.2E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00385 P450 superfamily signature 348 359 6.2E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00385 P450 superfamily signature 236 253 6.2E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 PRINTS PR00385 P450 superfamily signature 271 282 6.2E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS42830 d2dfb01b5b43fd18f31a0a363605bfad 414 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 SUPERFAMILY SSF46894 145 217 4.76E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 210 1.5E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 Gene3D G3DSA:1.10.10.10 135 214 5.5E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 Gene3D G3DSA:3.40.50.2300 2 134 1.6E-40 T 28-03-2018 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 4.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 4.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 4.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 Pfam PF00072 Response regulator receiver domain 5 117 7.9E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 SMART SM00448 3 116 6.2E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 SMART SM00421 153 210 1.1E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS40210 b80676dad9deacac109eea28c9475143 225 SUPERFAMILY SSF52172 2 135 1.08E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS35840 bee8c91e122d5fc02464c91c576cd977 107 Pfam PF01844 HNH endonuclease 61 101 3.0E-14 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMD44_RS35840 bee8c91e122d5fc02464c91c576cd977 107 SMART SM00507 48 98 6.5E-11 T 28-03-2018 IPR003615 HNH nuclease SMD44_RS35840 bee8c91e122d5fc02464c91c576cd977 107 Gene3D G3DSA:3.40.1800.10 36 107 3.7E-17 T 28-03-2018 SMD44_RS09145 d981f2d136d7226a778e007d156d247c 379 Pfam PF13579 Glycosyl transferase 4-like domain 27 170 2.5E-20 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS09145 d981f2d136d7226a778e007d156d247c 379 SUPERFAMILY SSF53756 25 372 5.71E-61 T 28-03-2018 SMD44_RS09145 d981f2d136d7226a778e007d156d247c 379 Gene3D G3DSA:3.40.50.2000 11 189 1.6E-15 T 28-03-2018 SMD44_RS09145 d981f2d136d7226a778e007d156d247c 379 Pfam PF00534 Glycosyl transferases group 1 191 345 9.0E-25 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS09145 d981f2d136d7226a778e007d156d247c 379 Gene3D G3DSA:3.40.50.2000 190 354 5.5E-34 T 28-03-2018 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 Gene3D G3DSA:2.30.40.10 69 148 7.5E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 SUPERFAMILY SSF51338 420 483 9.25E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 ProSitePatterns PS00145 Urease active site. 324 340 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 SUPERFAMILY SSF51556 487 573 1.89E-180 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 SUPERFAMILY SSF51556 136 438 1.89E-180 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 Pfam PF01979 Amidohydrolase family 132 456 8.9E-64 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 573 7.2E-263 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 SUPERFAMILY SSF51338 2 183 2.75E-56 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 Gene3D G3DSA:3.20.20.140 427 559 2.0E-42 T 28-03-2018 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 Gene3D G3DSA:3.20.20.140 149 426 6.1E-148 T 28-03-2018 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 407 422 1.2E-30 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 433 446 1.2E-30 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 1.2E-30 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 1.2E-30 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 Hamap MF_01953 Urease subunit alpha [ureC]. 2 573 54.797 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05745 fe0613a7ac8a348f795da87cdc6da09a 573 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 125 3.6E-53 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS37720 bf19a0732d333cc5194f9c374d52c10a 289 SUPERFAMILY SSF53474 2 286 2.81E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS37720 bf19a0732d333cc5194f9c374d52c10a 289 Pfam PF12697 Alpha/beta hydrolase family 44 264 3.7E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS37720 bf19a0732d333cc5194f9c374d52c10a 289 Gene3D G3DSA:3.40.50.1820 1 289 6.3E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 Pfam PF01084 Ribosomal protein S18 21 71 7.1E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 Gene3D G3DSA:4.10.640.10 1 78 6.9E-32 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 73 3.0E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 8.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 8.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 8.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 8.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 20.759 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 SUPERFAMILY SSF46911 5 75 3.4E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20975 5ee84d89cedb92b66bde220443698666 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 2.3E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS12185 7a5dc2c63f43d4082de41c3682c042cf 523 PIRSF PIRSF011396 1 523 1.2E-153 T 28-03-2018 IPR033856 Flavin-dependent tryptophan halogenase SMD44_RS12185 7a5dc2c63f43d4082de41c3682c042cf 523 Gene3D G3DSA:3.50.50.60 1 383 2.1E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS12185 7a5dc2c63f43d4082de41c3682c042cf 523 Pfam PF04820 Tryptophan halogenase 8 485 7.4E-143 T 28-03-2018 IPR006905 Flavin-dependent halogenase SMD44_RS12185 7a5dc2c63f43d4082de41c3682c042cf 523 SUPERFAMILY SSF51905 157 254 1.51E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS12185 7a5dc2c63f43d4082de41c3682c042cf 523 SUPERFAMILY SSF51905 7 90 1.51E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS12185 7a5dc2c63f43d4082de41c3682c042cf 523 SUPERFAMILY SSF51905 343 425 1.51E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16510 7c45d6353fb5980f2bf512f47b345684 387 Gene3D G3DSA:3.20.20.140 285 387 1.4E-21 T 28-03-2018 SMD44_RS16510 7c45d6353fb5980f2bf512f47b345684 387 Gene3D G3DSA:3.20.20.140 52 284 4.5E-51 T 28-03-2018 SMD44_RS16510 7c45d6353fb5980f2bf512f47b345684 387 SUPERFAMILY SSF51556 56 365 2.21E-53 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS16510 7c45d6353fb5980f2bf512f47b345684 387 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 62 362 9.0E-72 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 SMD44_RS01830 4e7104b220821918b7693ecb268caf8b 171 Gene3D G3DSA:2.70.50.50 31 171 1.5E-31 T 28-03-2018 SMD44_RS01830 4e7104b220821918b7693ecb268caf8b 171 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 5.1E-14 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMD44_RS01830 4e7104b220821918b7693ecb268caf8b 171 SUPERFAMILY SSF81296 31 170 2.94E-34 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 Gene3D G3DSA:3.50.50.60 2 379 1.0E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 Pfam PF01494 FAD binding domain 3 335 4.0E-91 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.6E-45 T 28-03-2018 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 1.6E-45 T 28-03-2018 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 1.6E-45 T 28-03-2018 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 320 1.6E-45 T 28-03-2018 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 1.6E-45 T 28-03-2018 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 1.6E-45 T 28-03-2018 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 SUPERFAMILY SSF51905 256 353 1.42E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS34665 a884780ab9b5df2397432af02695ee31 475 SUPERFAMILY SSF51905 1 164 1.42E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS02190 46b28c84450c5e2a859523db8ea9bdd1 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02190 46b28c84450c5e2a859523db8ea9bdd1 194 SUPERFAMILY SSF46689 13 89 3.49E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS02190 46b28c84450c5e2a859523db8ea9bdd1 194 Gene3D G3DSA:1.10.357.10 63 189 2.6E-26 T 28-03-2018 SMD44_RS02190 46b28c84450c5e2a859523db8ea9bdd1 194 Gene3D G3DSA:1.10.10.60 2 62 2.7E-11 T 28-03-2018 SMD44_RS02190 46b28c84450c5e2a859523db8ea9bdd1 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02190 46b28c84450c5e2a859523db8ea9bdd1 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02190 46b28c84450c5e2a859523db8ea9bdd1 194 SUPERFAMILY SSF48498 84 188 1.14E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 Pfam PF13649 Methyltransferase domain 264 327 2.4E-6 T 28-03-2018 SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 SUPERFAMILY SSF53335 236 374 4.94E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 Gene3D G3DSA:3.30.950.10 111 199 5.6E-25 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 Gene3D G3DSA:3.40.1010.10 4 110 1.1E-8 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 PIRSF PIRSF036428 1 403 2.4E-90 T 28-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 183 7.5E-17 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 SUPERFAMILY SSF53790 8 197 2.62E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 9 196 8.3E-36 T 28-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 SMD44_RS07665 49b5cdb145653b06389f24f8ef76f537 409 Gene3D G3DSA:3.40.50.150 246 401 3.0E-17 T 28-03-2018 SMD44_RS01885 2cf9df01503cd5a2dce95f850472c0a4 326 Gene3D G3DSA:3.20.20.140 22 326 2.9E-43 T 28-03-2018 SMD44_RS01885 2cf9df01503cd5a2dce95f850472c0a4 326 Pfam PF04909 Amidohydrolase 80 323 1.9E-32 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS01885 2cf9df01503cd5a2dce95f850472c0a4 326 SUPERFAMILY SSF51556 79 324 1.57E-50 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS30775 51425c6bc2cd0521c7f8c998911f8e58 481 Gene3D G3DSA:3.40.605.10 2 267 2.2E-67 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS30775 51425c6bc2cd0521c7f8c998911f8e58 481 SUPERFAMILY SSF53720 5 476 1.44E-129 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS30775 51425c6bc2cd0521c7f8c998911f8e58 481 Gene3D G3DSA:3.40.309.10 268 460 1.1E-60 T 28-03-2018 SMD44_RS30775 51425c6bc2cd0521c7f8c998911f8e58 481 Pfam PF00171 Aldehyde dehydrogenase family 16 471 5.5E-132 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS43650 ad65c91fb41b92eab5fe9f9f0355fc22 367 Pfam PF10935 Protein of unknown function (DUF2637) 22 139 1.5E-11 T 28-03-2018 IPR021235 Protein of unknown function DUF2637 SMD44_RS43110 4622c085446c8156ef9014448056b615 201 Gene3D G3DSA:3.40.190.10 13 156 3.7E-6 T 28-03-2018 SMD44_RS11195 c254fdf15fcde0df9ff9c3499b0065ee 99 Pfam PF04324 BFD-like [2Fe-2S] binding domain 5 53 8.6E-11 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SMD44_RS25775 3377658a8e037bb99290774a90539676 542 Gene3D G3DSA:3.50.7.10 190 373 2.2E-91 T 28-03-2018 IPR027409 GroEL-like apical domain SMD44_RS25775 3377658a8e037bb99290774a90539676 542 Gene3D G3DSA:1.10.560.10 1 189 3.3E-39 T 28-03-2018 IPR027413 GroEL-like equatorial domain SMD44_RS25775 3377658a8e037bb99290774a90539676 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 6.0E-94 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 PRINTS PR00298 60kDa chaperonin signature 82 109 3.7E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 PRINTS PR00298 60kDa chaperonin signature 26 52 3.7E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 PRINTS PR00298 60kDa chaperonin signature 350 375 3.7E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 PRINTS PR00298 60kDa chaperonin signature 268 291 3.7E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 PRINTS PR00298 60kDa chaperonin signature 398 419 3.7E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 SUPERFAMILY SSF54849 136 202 3.2E-24 T 28-03-2018 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 4.0E-244 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 SUPERFAMILY SSF48592 6 133 2.17E-74 T 28-03-2018 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 SUPERFAMILY SSF48592 406 521 2.17E-74 T 28-03-2018 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.61 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS25775 3377658a8e037bb99290774a90539676 542 Gene3D G3DSA:1.10.560.10 374 516 3.8E-24 T 28-03-2018 IPR027413 GroEL-like equatorial domain SMD44_RS25775 3377658a8e037bb99290774a90539676 542 SUPERFAMILY SSF52029 184 376 2.09E-79 T 28-03-2018 IPR027409 GroEL-like apical domain SMD44_RS22340 5f6e4a8f4e405f79d74b60fe1086de9f 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS22340 5f6e4a8f4e405f79d74b60fe1086de9f 202 SUPERFAMILY SSF48498 84 194 1.95E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS22340 5f6e4a8f4e405f79d74b60fe1086de9f 202 Gene3D G3DSA:1.10.10.60 6 63 3.1E-13 T 28-03-2018 SMD44_RS22340 5f6e4a8f4e405f79d74b60fe1086de9f 202 Gene3D G3DSA:1.10.357.10 64 197 2.8E-16 T 28-03-2018 SMD44_RS22340 5f6e4a8f4e405f79d74b60fe1086de9f 202 SUPERFAMILY SSF46689 5 85 4.57E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00330 c022fea995e351ac2fa21e9d3f003e6e 332 Gene3D G3DSA:1.10.10.10 1 95 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00330 c022fea995e351ac2fa21e9d3f003e6e 332 Pfam PF00196 Bacterial regulatory proteins, luxR family 266 319 1.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00330 c022fea995e351ac2fa21e9d3f003e6e 332 SUPERFAMILY SSF46894 254 327 1.33E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS00330 c022fea995e351ac2fa21e9d3f003e6e 332 SMART SM00421 264 321 6.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00330 c022fea995e351ac2fa21e9d3f003e6e 332 Gene3D G3DSA:1.10.10.10 258 326 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25555 97d68cbf1f2e84c493263c3a950eb4cd 107 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 101 21.237 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25555 97d68cbf1f2e84c493263c3a950eb4cd 107 Gene3D G3DSA:2.30.30.30 1 96 3.1E-32 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SMD44_RS25555 97d68cbf1f2e84c493263c3a950eb4cd 107 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 8.8E-23 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25555 97d68cbf1f2e84c493263c3a950eb4cd 107 Pfam PF00467 KOW motif 5 36 1.4E-7 T 28-03-2018 IPR005824 KOW SMD44_RS25555 97d68cbf1f2e84c493263c3a950eb4cd 107 SMART SM00739 2 29 1.0E-5 T 28-03-2018 IPR005824 KOW SMD44_RS25555 97d68cbf1f2e84c493263c3a950eb4cd 107 SUPERFAMILY SSF50104 1 105 7.52E-30 T 28-03-2018 IPR008991 Translation protein SH3-like domain SMD44_RS25555 97d68cbf1f2e84c493263c3a950eb4cd 107 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25555 97d68cbf1f2e84c493263c3a950eb4cd 107 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 2.0E-35 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS22870 bd2743ee829e6ef309b0dbb07c066ffb 180 SUPERFAMILY SSF55729 6 166 3.15E-6 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS22870 bd2743ee829e6ef309b0dbb07c066ffb 180 Gene3D G3DSA:3.40.630.30 4 163 5.7E-8 T 28-03-2018 SMD44_RS27830 e852972a1c46d36d5b91a0252f974971 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 3.0E-81 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 SMD44_RS27830 e852972a1c46d36d5b91a0252f974971 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS27830 e852972a1c46d36d5b91a0252f974971 286 Pfam PF00809 Pterin binding enzyme 17 257 1.4E-64 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS27830 e852972a1c46d36d5b91a0252f974971 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS27830 e852972a1c46d36d5b91a0252f974971 286 Gene3D G3DSA:3.20.20.20 1 286 6.0E-86 T 28-03-2018 SMD44_RS27830 e852972a1c46d36d5b91a0252f974971 286 SUPERFAMILY SSF51717 4 275 1.02E-81 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 SMART SM00895 94 221 2.0E-18 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 SMART SM00345 15 74 4.9E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 SUPERFAMILY SSF46785 7 78 2.98E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 Gene3D G3DSA:1.20.120.530 76 232 6.0E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 SUPERFAMILY SSF48008 92 225 1.44E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 Pfam PF07729 FCD domain 94 215 3.8E-22 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 4.1E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 Gene3D G3DSA:1.10.10.10 5 75 2.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.3E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS29610 be8951f5fd94a78aa2fd16a1defa3222 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.3E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS40915 c41d44142490a87a8a177f18868b1787 68 SMART SM00923 8 60 2.2E-17 T 28-03-2018 IPR005153 MbtH-like protein SMD44_RS40915 c41d44142490a87a8a177f18868b1787 68 Pfam PF03621 MbtH-like protein 8 59 7.0E-20 T 28-03-2018 IPR005153 MbtH-like protein SMD44_RS40915 c41d44142490a87a8a177f18868b1787 68 Gene3D G3DSA:3.90.820.10 7 63 1.5E-19 T 28-03-2018 SMD44_RS40915 c41d44142490a87a8a177f18868b1787 68 SUPERFAMILY SSF160582 12 60 6.15E-16 T 28-03-2018 SMD44_RS22300 06fa64160da4408569d520f5d5357959 411 SUPERFAMILY SSF53300 265 370 1.54E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS22300 06fa64160da4408569d520f5d5357959 411 Pfam PF09967 VWA-like domain (DUF2201) 271 381 1.7E-14 T 28-03-2018 IPR018698 VWA-like domain SMD44_RS22300 06fa64160da4408569d520f5d5357959 411 Pfam PF13203 Putative metallopeptidase domain 10 264 1.9E-24 T 28-03-2018 IPR025154 Putative metallopeptidase domain SMD44_RS22300 06fa64160da4408569d520f5d5357959 411 Gene3D G3DSA:3.40.50.410 260 384 3.8E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS41915 3124c901b30b79d5702d42bdbda5eb6c 147 Pfam PF00664 ABC transporter transmembrane region 19 107 1.0E-8 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS41915 3124c901b30b79d5702d42bdbda5eb6c 147 SUPERFAMILY SSF90123 4 107 5.89E-22 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS41915 3124c901b30b79d5702d42bdbda5eb6c 147 Gene3D G3DSA:1.20.1560.10 2 115 1.6E-18 T 28-03-2018 SMD44_RS08545 ba31eee5743f27f190f7f967bfbaf3e0 442 SUPERFAMILY SSF53474 267 381 2.92E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS08545 ba31eee5743f27f190f7f967bfbaf3e0 442 Gene3D G3DSA:3.40.50.1820 43 435 6.4E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 Gene3D G3DSA:3.90.180.10 234 324 1.4E-7 T 28-03-2018 SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 SUPERFAMILY SSF50129 2 155 2.28E-32 T 28-03-2018 IPR011032 GroES-like SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 Gene3D G3DSA:3.90.180.10 1 148 8.0E-43 T 28-03-2018 SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 Gene3D G3DSA:3.40.50.720 149 233 1.4E-17 T 28-03-2018 SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 Pfam PF13602 Zinc-binding dehydrogenase 188 320 2.1E-24 T 28-03-2018 SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 SMART SM00829 10 320 2.3E-24 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 93 4.9E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 SUPERFAMILY SSF51735 280 319 1.04E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS00835 32541b63b005edffe0a2f32e715eefda 329 SUPERFAMILY SSF51735 118 237 1.04E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS15620 1a2fa33b028a993eeafc62aa9b90ea45 243 Pfam PF03725 3' exoribonuclease family, domain 2 162 224 3.4E-10 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS15620 1a2fa33b028a993eeafc62aa9b90ea45 243 SUPERFAMILY SSF55666 156 241 2.36E-24 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS15620 1a2fa33b028a993eeafc62aa9b90ea45 243 Gene3D G3DSA:3.30.230.70 2 243 3.9E-62 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS15620 1a2fa33b028a993eeafc62aa9b90ea45 243 SUPERFAMILY SSF54211 3 183 7.09E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS15620 1a2fa33b028a993eeafc62aa9b90ea45 243 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site SMD44_RS15620 1a2fa33b028a993eeafc62aa9b90ea45 243 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 1.0E-24 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS15620 1a2fa33b028a993eeafc62aa9b90ea45 243 Hamap MF_00564 Ribonuclease PH [rph]. 2 240 47.379 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 SMD44_RS15620 1a2fa33b028a993eeafc62aa9b90ea45 243 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 239 1.1E-115 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 SMD44_RS32515 29b199a02ecef204c8ee4e64cecf82c9 135 Gene3D G3DSA:2.170.150.20 1 135 4.6E-57 T 28-03-2018 SMD44_RS32515 29b199a02ecef204c8ee4e64cecf82c9 135 Pfam PF01641 SelR domain 11 130 2.9E-53 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SMD44_RS32515 29b199a02ecef204c8ee4e64cecf82c9 135 SUPERFAMILY SSF51316 6 133 3.84E-55 T 28-03-2018 IPR011057 Mss4-like SMD44_RS32515 29b199a02ecef204c8ee4e64cecf82c9 135 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 132 8.5E-50 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SMD44_RS20435 4b60763e59356735b2f44953118a6ded 296 Gene3D G3DSA:3.20.20.80 64 295 6.4E-51 T 28-03-2018 SMD44_RS20435 4b60763e59356735b2f44953118a6ded 296 SUPERFAMILY SSF51445 64 291 2.63E-34 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS20435 4b60763e59356735b2f44953118a6ded 296 Pfam PF08924 Domain of unknown function (DUF1906) 76 212 1.1E-32 T 28-03-2018 IPR015020 Protein of unknown function DUF1906 SMD44_RS31335 d50dd3b7038c0d7c4f3fd6125f062dad 168 Gene3D G3DSA:3.40.630.30 12 120 5.3E-6 T 28-03-2018 SMD44_RS41235 840d4b327d2b29e86c298e555060f6db 567 Gene3D G3DSA:3.80.30.20 208 435 8.4E-10 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SMD44_RS41235 840d4b327d2b29e86c298e555060f6db 567 Pfam PF02310 B12 binding domain 27 140 4.5E-12 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS41235 840d4b327d2b29e86c298e555060f6db 567 Gene3D G3DSA:3.40.50.280 23 153 4.1E-8 T 28-03-2018 SMD44_RS41235 840d4b327d2b29e86c298e555060f6db 567 SUPERFAMILY SSF102114 207 383 3.14E-12 T 28-03-2018 SMD44_RS17775 4fdec82e04b54637b785fcd4d432f264 311 SUPERFAMILY SSF56563 4 306 1.96E-10 T 28-03-2018 SMD44_RS35505 d4907b6d25856c72723af058278c7eed 299 SUPERFAMILY SSF48576 17 292 5.61E-56 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS35505 d4907b6d25856c72723af058278c7eed 299 Pfam PF00494 Squalene/phytoene synthase 17 284 5.1E-64 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMD44_RS35505 d4907b6d25856c72723af058278c7eed 299 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 16 293 3.6E-95 T 28-03-2018 IPR017827 Squalene synthase HpnC SMD44_RS35505 d4907b6d25856c72723af058278c7eed 299 Gene3D G3DSA:1.10.600.10 2 297 2.0E-69 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS25935 bfca015b10ee9ccf9b3ffd5af6a537cd 429 Pfam PF04024 PspC domain 16 71 1.7E-13 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal SMD44_RS25935 bfca015b10ee9ccf9b3ffd5af6a537cd 429 Gene3D G3DSA:3.30.565.10 294 429 8.6E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS25935 bfca015b10ee9ccf9b3ffd5af6a537cd 429 Pfam PF13581 Histidine kinase-like ATPase domain 297 389 1.3E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS25935 bfca015b10ee9ccf9b3ffd5af6a537cd 429 SUPERFAMILY SSF55874 309 422 2.75E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 Pfam PF00246 Zinc carboxypeptidase 136 396 1.2E-54 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 SUPERFAMILY SSF53187 134 406 3.84E-63 T 28-03-2018 SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 Gene3D G3DSA:2.60.120.260 711 907 1.7E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 Gene3D G3DSA:3.40.630.10 128 440 1.2E-54 T 28-03-2018 SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 317 330 6.2E-9 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 177 191 6.2E-9 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 263 271 6.2E-9 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 150 162 6.2E-9 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 Pfam PF05547 Immune inhibitor A peptidase M6 742 911 5.4E-8 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD44_RS10130 eec6974b38607ed2e39818edeea901cb 986 SMART SM00631 124 407 3.8E-64 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 SUPERFAMILY SSF52096 4 307 2.09E-54 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 Gene3D G3DSA:1.10.1040.10 514 607 1.5E-12 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 507 607 9.7E-17 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 210 7.5E-27 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 326 504 1.1E-64 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 SUPERFAMILY SSF48179 506 647 7.06E-15 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 Gene3D G3DSA:3.90.226.10 7 275 3.3E-45 T 28-03-2018 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 SUPERFAMILY SSF48179 635 727 3.57E-16 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 Gene3D G3DSA:1.10.1040.10 636 729 1.3E-15 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 Gene3D G3DSA:3.40.50.720 276 506 6.8E-69 T 28-03-2018 SMD44_RS35350 9f4f3f06fc61e0b14340cbd1c48b6145 730 SUPERFAMILY SSF51735 322 504 8.43E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS03600 7db01198f4dd9acae24e4084fa631e5c 297 Pfam PF13672 Protein phosphatase 2C 56 255 3.8E-21 T 28-03-2018 SMD44_RS03600 7db01198f4dd9acae24e4084fa631e5c 297 Gene3D G3DSA:3.60.40.10 38 281 8.7E-19 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS03600 7db01198f4dd9acae24e4084fa631e5c 297 SUPERFAMILY SSF81606 48 281 1.24E-18 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS04020 a1d94d5ffd7d4b28be5bd1be05e1d550 267 Pfam PF00005 ABC transporter 36 185 5.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS04020 a1d94d5ffd7d4b28be5bd1be05e1d550 267 SUPERFAMILY SSF52540 18 238 4.36E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS04020 a1d94d5ffd7d4b28be5bd1be05e1d550 267 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS04020 a1d94d5ffd7d4b28be5bd1be05e1d550 267 SMART SM00382 45 234 4.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS04020 a1d94d5ffd7d4b28be5bd1be05e1d550 267 Gene3D G3DSA:3.40.50.300 14 254 1.6E-58 T 28-03-2018 SMD44_RS14970 813789c84af6817da85af5a5bc7b915a 348 Gene3D G3DSA:3.40.50.1980 43 180 6.6E-15 T 28-03-2018 SMD44_RS14970 813789c84af6817da85af5a5bc7b915a 348 Gene3D G3DSA:3.40.50.1980 181 348 2.1E-23 T 28-03-2018 SMD44_RS14970 813789c84af6817da85af5a5bc7b915a 348 SUPERFAMILY SSF53807 51 341 3.06E-30 T 28-03-2018 SMD44_RS14970 813789c84af6817da85af5a5bc7b915a 348 Pfam PF01497 Periplasmic binding protein 74 317 2.8E-20 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS43580 df99585e33c16d45a94268e3707aa786 288 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 15 56 1.7E-12 T 28-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal SMD44_RS43580 df99585e33c16d45a94268e3707aa786 288 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 14 178 6.2E-54 T 28-03-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 SMD44_RS43580 df99585e33c16d45a94268e3707aa786 288 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 15 246 5.0E-46 T 28-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 SMD44_RS04900 5885ffacc270d206bf5b98cb797333e5 305 SUPERFAMILY SSF53474 5 286 7.36E-67 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS04900 5885ffacc270d206bf5b98cb797333e5 305 Pfam PF07859 alpha/beta hydrolase fold 56 267 6.6E-66 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMD44_RS04900 5885ffacc270d206bf5b98cb797333e5 305 Gene3D G3DSA:3.40.50.1820 2 296 2.3E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS04900 5885ffacc270d206bf5b98cb797333e5 305 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 128 140 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site SMD44_RS04900 5885ffacc270d206bf5b98cb797333e5 305 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 56 72 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 SMD44_RS01390 89aec9f5931b63ef49f802c5f0aaa293 231 Gene3D G3DSA:1.20.1660.10 12 113 1.3E-5 T 28-03-2018 SMD44_RS01390 89aec9f5931b63ef49f802c5f0aaa293 231 Pfam PF08713 DNA alkylation repair enzyme 15 214 1.1E-23 T 28-03-2018 IPR014825 DNA alkylation repair enzyme SMD44_RS01390 89aec9f5931b63ef49f802c5f0aaa293 231 SUPERFAMILY SSF48371 10 226 6.91E-64 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS15415 2f5dd5ff6a9cf0c09222d522eddff71f 250 Gene3D G3DSA:2.60.40.10 52 199 8.0E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS24570 db4bceadb4acd80288176ba5d64cc80a 338 SUPERFAMILY SSF53474 82 322 6.12E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24570 db4bceadb4acd80288176ba5d64cc80a 338 Pfam PF00756 Putative esterase 93 283 1.5E-14 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD44_RS24570 db4bceadb4acd80288176ba5d64cc80a 338 Gene3D G3DSA:3.40.50.1820 57 335 3.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 PRINTS PR00868 DNA-polymerase family A (pol I) signature 357 370 6.7E-8 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 PRINTS PR00868 DNA-polymerase family A (pol I) signature 481 497 6.7E-8 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 PRINTS PR00868 DNA-polymerase family A (pol I) signature 509 522 6.7E-8 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 PRINTS PR00868 DNA-polymerase family A (pol I) signature 327 350 6.7E-8 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 SMART SM00482 313 526 2.4E-11 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 Pfam PF00476 DNA polymerase family A 223 537 1.8E-27 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 Gene3D G3DSA:3.30.70.370 379 567 4.0E-23 T 28-03-2018 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 Gene3D G3DSA:3.30.70.370 289 378 1.7E-13 T 28-03-2018 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 SUPERFAMILY SSF56672 466 566 7.78E-64 T 28-03-2018 SMD44_RS23530 4a6214930d3c49256113aa9b831df343 567 SUPERFAMILY SSF56672 158 437 7.78E-64 T 28-03-2018 SMD44_RS28540 38c64741041af927b32516a1bd708f51 320 SUPERFAMILY SSF50129 6 154 4.55E-29 T 28-03-2018 IPR011032 GroES-like SMD44_RS28540 38c64741041af927b32516a1bd708f51 320 Pfam PF00107 Zinc-binding dehydrogenase 165 283 5.8E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS28540 38c64741041af927b32516a1bd708f51 320 Gene3D G3DSA:3.90.180.10 4 320 1.4E-62 T 28-03-2018 SMD44_RS28540 38c64741041af927b32516a1bd708f51 320 SUPERFAMILY SSF51735 126 287 1.08E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS28540 38c64741041af927b32516a1bd708f51 320 SMART SM00829 13 318 1.6E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 Pfam PF00067 Cytochrome P450 312 404 1.6E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00359 B-class P450 signature 311 322 1.1E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00359 B-class P450 signature 377 386 1.1E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00359 B-class P450 signature 328 355 1.1E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00359 B-class P450 signature 234 256 1.1E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00359 B-class P450 signature 386 397 1.1E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00359 B-class P450 signature 182 197 1.1E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00359 B-class P450 signature 114 125 1.1E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00359 B-class P450 signature 356 371 1.1E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 Gene3D G3DSA:1.10.630.10 21 435 6.1E-59 T 28-03-2018 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00385 P450 superfamily signature 377 386 5.6E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00385 P450 superfamily signature 386 397 5.6E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00385 P450 superfamily signature 311 322 5.6E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 PRINTS PR00385 P450 superfamily signature 276 293 5.6E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 SUPERFAMILY SSF48264 13 435 3.54E-74 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS32530 538bd6672952020283157ef9466b4f4e 436 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 379 388 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS17590 2367eda132ba7f89c16d592b819c61e9 649 Pfam PF00912 Transglycosylase 96 265 7.3E-55 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS17590 2367eda132ba7f89c16d592b819c61e9 649 SUPERFAMILY SSF53955 82 288 1.86E-61 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS17590 2367eda132ba7f89c16d592b819c61e9 649 SUPERFAMILY SSF56601 303 603 1.35E-46 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS17590 2367eda132ba7f89c16d592b819c61e9 649 SUPERFAMILY SSF56601 250 270 1.35E-46 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS17590 2367eda132ba7f89c16d592b819c61e9 649 Gene3D G3DSA:1.10.3810.10 83 283 1.6E-63 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS17590 2367eda132ba7f89c16d592b819c61e9 649 Pfam PF00905 Penicillin binding protein transpeptidase domain 440 593 3.0E-6 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS17590 2367eda132ba7f89c16d592b819c61e9 649 Gene3D G3DSA:3.40.710.10 289 423 1.0E-24 T 28-03-2018 SMD44_RS17590 2367eda132ba7f89c16d592b819c61e9 649 Gene3D G3DSA:3.40.710.10 424 639 2.5E-25 T 28-03-2018 SMD44_RS37535 7489d6508cdd78a4d2136a01c1c75b20 310 SUPERFAMILY SSF51445 30 299 7.67E-46 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS37535 7489d6508cdd78a4d2136a01c1c75b20 310 ProSitePatterns PS01095 Chitinases family 18 active site. 143 151 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS37535 7489d6508cdd78a4d2136a01c1c75b20 310 Gene3D G3DSA:3.20.20.80 26 310 2.0E-39 T 28-03-2018 SMD44_RS37535 7489d6508cdd78a4d2136a01c1c75b20 310 Pfam PF00704 Glycosyl hydrolases family 18 32 245 1.3E-14 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMD44_RS15525 4ca91fa81904577ea91be918c7ad1609 141 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 7 67 6.9E-7 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS15525 4ca91fa81904577ea91be918c7ad1609 141 Gene3D G3DSA:2.80.10.50 4 141 1.9E-21 T 28-03-2018 SMD44_RS15525 4ca91fa81904577ea91be918c7ad1609 141 SUPERFAMILY SSF50370 4 139 1.67E-21 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS05540 4a560b5da93bec3b0cc2639af6fa0fc3 197 Gene3D G3DSA:1.10.10.60 1 73 7.5E-19 T 28-03-2018 SMD44_RS05540 4a560b5da93bec3b0cc2639af6fa0fc3 197 Gene3D G3DSA:1.10.357.10 74 197 3.4E-21 T 28-03-2018 SMD44_RS05540 4a560b5da93bec3b0cc2639af6fa0fc3 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 4.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05540 4a560b5da93bec3b0cc2639af6fa0fc3 197 SUPERFAMILY SSF48498 88 196 2.11E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS05540 4a560b5da93bec3b0cc2639af6fa0fc3 197 SUPERFAMILY SSF46689 14 77 3.54E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05540 4a560b5da93bec3b0cc2639af6fa0fc3 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05540 4a560b5da93bec3b0cc2639af6fa0fc3 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04910 050fc86d253e7b2c27836e7e5f5bad4b 239 SMART SM00563 35 154 9.3E-30 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS04910 050fc86d253e7b2c27836e7e5f5bad4b 239 SUPERFAMILY SSF69593 2 217 8.24E-49 T 28-03-2018 SMD44_RS04910 050fc86d253e7b2c27836e7e5f5bad4b 239 Pfam PF01553 Acyltransferase 21 151 1.7E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS04910 050fc86d253e7b2c27836e7e5f5bad4b 239 Gene3D G3DSA:3.40.1130.10 1 230 3.1E-50 T 28-03-2018 SMD44_RS29830 12d6307ed4137a47c30271353228af18 500 Gene3D G3DSA:3.90.1300.10 5 491 9.8E-168 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS29830 12d6307ed4137a47c30271353228af18 500 Pfam PF01425 Amidase 28 474 5.1E-158 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS29830 12d6307ed4137a47c30271353228af18 500 ProSitePatterns PS00571 Amidases signature. 156 187 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMD44_RS29830 12d6307ed4137a47c30271353228af18 500 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 15 486 89.31 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS29830 12d6307ed4137a47c30271353228af18 500 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 18 485 1.1E-186 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS29830 12d6307ed4137a47c30271353228af18 500 SUPERFAMILY SSF75304 5 484 5.63E-159 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS25235 9a7b2f980df34d4f1014535c869c31e6 360 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 72 219 1.3E-29 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD44_RS25235 9a7b2f980df34d4f1014535c869c31e6 360 SUPERFAMILY SSF52518 36 359 8.94E-85 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS25235 9a7b2f980df34d4f1014535c869c31e6 360 Gene3D G3DSA:3.40.50.970 101 249 1.1E-40 T 28-03-2018 SMD44_RS25235 9a7b2f980df34d4f1014535c869c31e6 360 Gene3D G3DSA:3.40.50.970 16 100 2.3E-22 T 28-03-2018 SMD44_RS15870 96fe90e752c59a848367bb9cc1191669 190 Gene3D G3DSA:1.10.10.10 98 186 1.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15870 96fe90e752c59a848367bb9cc1191669 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 154 5.1E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15870 96fe90e752c59a848367bb9cc1191669 190 Gene3D G3DSA:1.10.1740.10 2 90 3.0E-18 T 28-03-2018 SMD44_RS15870 96fe90e752c59a848367bb9cc1191669 190 SUPERFAMILY SSF88946 3 91 4.32E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15870 96fe90e752c59a848367bb9cc1191669 190 SUPERFAMILY SSF88659 97 155 1.46E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15870 96fe90e752c59a848367bb9cc1191669 190 Pfam PF04542 Sigma-70 region 2 10 76 1.1E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15870 96fe90e752c59a848367bb9cc1191669 190 Pfam PF08281 Sigma-70, region 4 100 150 7.0E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15870 96fe90e752c59a848367bb9cc1191669 190 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 2 155 2.7E-52 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.0E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.0E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 SUPERFAMILY SSF100950 76 235 2.3E-29 T 28-03-2018 SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 2.4E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 Gene3D G3DSA:1.10.10.10 2 65 7.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 SMART SM01134 73 234 1.4E-65 T 28-03-2018 SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 Gene3D G3DSA:3.40.50.1360 66 232 7.0E-39 T 28-03-2018 SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 SUPERFAMILY SSF46785 5 59 2.15E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 Pfam PF00455 DeoR C terminal sensor domain 76 233 2.1E-50 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 SMART SM00420 6 58 2.8E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS26945 d3c5b8e2821870fc035923fa80cbc4eb 329 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD44_RS22585 75ed86b9bf2c686efef51d424867edc6 529 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 215 515 18.769 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SMD44_RS22585 75ed86b9bf2c686efef51d424867edc6 529 Gene3D G3DSA:3.40.50.150 286 508 7.2E-38 T 28-03-2018 SMD44_RS22585 75ed86b9bf2c686efef51d424867edc6 529 SUPERFAMILY SSF53335 239 461 5.81E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS22585 75ed86b9bf2c686efef51d424867edc6 529 Pfam PF01564 Spermine/spermidine synthase domain 289 447 9.2E-23 T 28-03-2018 SMD44_RS22585 75ed86b9bf2c686efef51d424867edc6 529 SUPERFAMILY SSF103473 18 206 4.19E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26290 6e23396aa15b240f4611ad7e3944706f 188 Gene3D G3DSA:1.10.10.60 1 63 8.9E-16 T 28-03-2018 SMD44_RS26290 6e23396aa15b240f4611ad7e3944706f 188 SUPERFAMILY SSF48498 79 188 1.78E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS26290 6e23396aa15b240f4611ad7e3944706f 188 SUPERFAMILY SSF46689 12 72 7.48E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS26290 6e23396aa15b240f4611ad7e3944706f 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 65 1.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS26290 6e23396aa15b240f4611ad7e3944706f 188 Gene3D G3DSA:1.10.357.10 64 188 8.8E-18 T 28-03-2018 SMD44_RS26290 6e23396aa15b240f4611ad7e3944706f 188 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 186 3.1E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS26290 6e23396aa15b240f4611ad7e3944706f 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS26290 6e23396aa15b240f4611ad7e3944706f 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21950 88965921d72573472aca933b755bfd2e 283 Pfam PF13560 Helix-turn-helix domain 13 69 2.7E-12 T 28-03-2018 SMD44_RS21950 88965921d72573472aca933b755bfd2e 283 Gene3D G3DSA:1.10.260.40 4 115 1.0E-11 T 28-03-2018 SMD44_RS21950 88965921d72573472aca933b755bfd2e 283 SUPERFAMILY SSF47413 10 69 3.49E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS21950 88965921d72573472aca933b755bfd2e 283 SMART SM00530 17 72 7.4E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS36320 645c624ed349c9502b041760f5ef6e70 269 Gene3D G3DSA:3.40.50.150 3 269 1.0E-49 T 28-03-2018 SMD44_RS36320 645c624ed349c9502b041760f5ef6e70 269 PIRSF PIRSF017393 2 269 1.6E-90 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS36320 645c624ed349c9502b041760f5ef6e70 269 SUPERFAMILY SSF53335 16 252 2.35E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS36320 645c624ed349c9502b041760f5ef6e70 269 Pfam PF04672 S-adenosyl methyltransferase 8 268 4.2E-103 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 Gene3D G3DSA:3.40.50.720 286 492 7.7E-52 T 28-03-2018 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 Gene3D G3DSA:3.40.50.720 2 186 9.1E-49 T 28-03-2018 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 SUPERFAMILY SSF51735 310 491 2.17E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 314 491 6.8E-59 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 185 1.6E-58 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 494 590 1.8E-32 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 284 5.0E-29 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 SUPERFAMILY SSF48179 187 288 3.91E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 SUPERFAMILY SSF51735 5 187 9.67E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 SUPERFAMILY SSF48179 494 591 3.4E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 Gene3D G3DSA:1.10.1040.10 493 593 3.8E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS34205 849c2ebf7cf350e810a48784cdd804fd 593 Gene3D G3DSA:1.10.1040.10 187 285 1.2E-27 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS29135 3eef0e0764c6e579acea35c0cc8aa899 110 Pfam PF12823 Domain of unknown function (DUF3817) 6 94 1.0E-26 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SMD44_RS29135 3eef0e0764c6e579acea35c0cc8aa899 110 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 1.8E-26 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SMD44_RS21310 e4decb14c2c6063c23e931d71b355aee 425 SUPERFAMILY SSF53756 16 413 3.81E-78 T 28-03-2018 SMD44_RS21310 e4decb14c2c6063c23e931d71b355aee 425 Pfam PF13439 Glycosyltransferase Family 4 22 179 9.7E-27 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS21310 e4decb14c2c6063c23e931d71b355aee 425 Gene3D G3DSA:3.40.50.2000 188 395 9.7E-45 T 28-03-2018 SMD44_RS21310 e4decb14c2c6063c23e931d71b355aee 425 Pfam PF13692 Glycosyl transferases group 1 211 376 1.5E-33 T 28-03-2018 SMD44_RS21310 e4decb14c2c6063c23e931d71b355aee 425 Gene3D G3DSA:3.40.50.2000 5 187 1.8E-23 T 28-03-2018 SMD44_RS37765 0ee92019d598f7e09c63b5766dce07e4 288 Gene3D G3DSA:1.10.1040.10 161 288 5.0E-11 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS37765 0ee92019d598f7e09c63b5766dce07e4 288 PIRSF PIRSF000103 2 288 1.8E-35 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS37765 0ee92019d598f7e09c63b5766dce07e4 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 160 3.3E-19 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS37765 0ee92019d598f7e09c63b5766dce07e4 288 SUPERFAMILY SSF51735 6 160 4.37E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS37765 0ee92019d598f7e09c63b5766dce07e4 288 Gene3D G3DSA:3.40.50.720 3 160 1.1E-25 T 28-03-2018 SMD44_RS02700 d217f95789cbd88a7c1723a571fb1e49 235 Pfam PF03243 Alkylmercury lyase 82 201 3.2E-14 T 28-03-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 SMD44_RS02700 d217f95789cbd88a7c1723a571fb1e49 235 Gene3D G3DSA:1.10.10.10 5 207 5.7E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02700 d217f95789cbd88a7c1723a571fb1e49 235 SUPERFAMILY SSF160387 93 210 2.04E-15 T 28-03-2018 SMD44_RS25065 48900faadef5c151ed5f9951de6301b1 297 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 27 172 7.0E-32 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS01605 5e81aa977f10ebf46d4adea3d33975a3 168 Gene3D G3DSA:1.10.10.10 12 164 2.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01605 5e81aa977f10ebf46d4adea3d33975a3 168 Pfam PF01638 HxlR-like helix-turn-helix 30 117 2.3E-15 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS01605 5e81aa977f10ebf46d4adea3d33975a3 168 SUPERFAMILY SSF46785 19 123 1.18E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39630 63c88f6633cda6e0938ccbc049ec4f5c 589 Gene3D G3DSA:3.40.50.980 28 201 5.8E-36 T 28-03-2018 SMD44_RS39630 63c88f6633cda6e0938ccbc049ec4f5c 589 Gene3D G3DSA:2.30.38.10 397 470 4.9E-22 T 28-03-2018 SMD44_RS39630 63c88f6633cda6e0938ccbc049ec4f5c 589 Gene3D G3DSA:3.40.50.980 202 370 3.3E-32 T 28-03-2018 SMD44_RS39630 63c88f6633cda6e0938ccbc049ec4f5c 589 SUPERFAMILY SSF56801 28 579 2.62E-108 T 28-03-2018 SMD44_RS39630 63c88f6633cda6e0938ccbc049ec4f5c 589 Gene3D G3DSA:3.30.300.30 471 578 4.3E-18 T 28-03-2018 SMD44_RS39630 63c88f6633cda6e0938ccbc049ec4f5c 589 Pfam PF00501 AMP-binding enzyme 39 478 5.1E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS23945 c0ddd3c38feba38d659c74bcd681171e 310 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 167 3.8E-10 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD44_RS23945 c0ddd3c38feba38d659c74bcd681171e 310 SUPERFAMILY SSF48150 22 235 2.51E-59 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD44_RS23945 c0ddd3c38feba38d659c74bcd681171e 310 Gene3D G3DSA:1.10.340.30 38 136 3.9E-28 T 28-03-2018 SMD44_RS23945 c0ddd3c38feba38d659c74bcd681171e 310 SMART SM00478 57 209 2.4E-31 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD44_RS23945 c0ddd3c38feba38d659c74bcd681171e 310 Pfam PF00633 Helix-hairpin-helix motif 117 146 1.8E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SMD44_RS23945 c0ddd3c38feba38d659c74bcd681171e 310 Gene3D G3DSA:1.10.1670.10 137 243 2.8E-32 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMD44_RS23945 c0ddd3c38feba38d659c74bcd681171e 310 ProSitePatterns PS01155 Endonuclease III family signature. 120 149 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 SMD44_RS21560 d7810b213307585d5ffe892cb72215ef 387 Gene3D G3DSA:3.40.630.30 282 355 4.4E-4 T 28-03-2018 SMD44_RS21560 d7810b213307585d5ffe892cb72215ef 387 Gene3D G3DSA:3.40.630.30 1 154 2.2E-16 T 28-03-2018 SMD44_RS21560 d7810b213307585d5ffe892cb72215ef 387 SUPERFAMILY SSF55729 8 148 7.39E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS21560 d7810b213307585d5ffe892cb72215ef 387 Pfam PF00583 Acetyltransferase (GNAT) family 46 137 1.0E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS27430 46c21e4a752b4ab472158cc53366b3cd 254 Gene3D G3DSA:1.10.530.10 106 254 1.1E-21 T 28-03-2018 SMD44_RS27430 46c21e4a752b4ab472158cc53366b3cd 254 Pfam PF01464 Transglycosylase SLT domain 178 241 1.2E-7 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 SMD44_RS27430 46c21e4a752b4ab472158cc53366b3cd 254 SUPERFAMILY SSF53955 181 247 5.2E-11 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS25565 90cdd5a02534ff861adc3748e75338f1 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25565 90cdd5a02534ff861adc3748e75338f1 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.154 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z SMD44_RS25565 90cdd5a02534ff861adc3748e75338f1 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 2.3E-24 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25565 90cdd5a02534ff861adc3748e75338f1 61 SUPERFAMILY SSF57716 4 61 7.84E-22 T 28-03-2018 SMD44_RS25565 90cdd5a02534ff861adc3748e75338f1 61 Gene3D G3DSA:4.10.830.10 1 61 4.3E-22 T 28-03-2018 SMD44_RS31710 abf09b356a62a34a68e4f2da42ae5328 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 2.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS31710 abf09b356a62a34a68e4f2da42ae5328 217 Pfam PF00072 Response regulator receiver domain 3 113 1.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31710 abf09b356a62a34a68e4f2da42ae5328 217 SUPERFAMILY SSF52172 2 171 9.96E-35 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS31710 abf09b356a62a34a68e4f2da42ae5328 217 SMART SM00862 145 217 8.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS31710 abf09b356a62a34a68e4f2da42ae5328 217 Gene3D G3DSA:1.10.10.10 117 217 9.7E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31710 abf09b356a62a34a68e4f2da42ae5328 217 SMART SM00448 1 112 6.5E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31710 abf09b356a62a34a68e4f2da42ae5328 217 Gene3D G3DSA:3.40.50.2300 1 116 1.1E-30 T 28-03-2018 SMD44_RS26245 0e1c6faf7f95d7738c810207674909e1 151 Gene3D G3DSA:1.10.10.10 28 127 4.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26245 0e1c6faf7f95d7738c810207674909e1 151 Pfam PF01638 HxlR-like helix-turn-helix 29 116 1.2E-28 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS26245 0e1c6faf7f95d7738c810207674909e1 151 SUPERFAMILY SSF46785 29 127 3.34E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01010 d4d9fd30caee8d3c446fac22ef2b819b 263 PIRSF PIRSF006648 1 263 6.0E-68 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS01010 d4d9fd30caee8d3c446fac22ef2b819b 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 185 204 3.3E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS01010 d4d9fd30caee8d3c446fac22ef2b819b 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 205 224 3.3E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS01010 d4d9fd30caee8d3c446fac22ef2b819b 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 108 133 3.3E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS01010 d4d9fd30caee8d3c446fac22ef2b819b 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 29 50 3.3E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS01010 d4d9fd30caee8d3c446fac22ef2b819b 263 Pfam PF01061 ABC-2 type transporter 12 227 3.8E-29 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS37995 766def9f46b1031fe8b63aae97de7f93 303 Pfam PF13672 Protein phosphatase 2C 147 237 9.4E-9 T 28-03-2018 SMD44_RS19565 433565dc1f85a53a09c7775d8675f8bf 269 SUPERFAMILY SSF46689 34 117 1.25E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS19565 433565dc1f85a53a09c7775d8675f8bf 269 Gene3D G3DSA:1.10.10.60 79 99 1.7E-9 T 28-03-2018 SMD44_RS19565 433565dc1f85a53a09c7775d8675f8bf 269 SUPERFAMILY SSF48498 195 266 1.89E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS19565 433565dc1f85a53a09c7775d8675f8bf 269 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 91 5.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19565 433565dc1f85a53a09c7775d8675f8bf 269 Gene3D G3DSA:1.10.10.60 24 78 1.3E-14 T 28-03-2018 SMD44_RS19565 433565dc1f85a53a09c7775d8675f8bf 269 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 60 9.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19565 433565dc1f85a53a09c7775d8675f8bf 269 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 67 90 9.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19565 433565dc1f85a53a09c7775d8675f8bf 269 Gene3D G3DSA:1.10.357.10 100 269 1.1E-34 T 28-03-2018 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 Gene3D G3DSA:3.40.50.880 2 229 7.4E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS12580 c06c2d502012403a222a357677253d05 320 SUPERFAMILY SSF46689 265 314 1.57E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 Gene3D G3DSA:1.10.10.60 264 320 3.5E-16 T 28-03-2018 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 SUPERFAMILY SSF46689 216 263 3.76E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 Pfam PF01965 DJ-1/PfpI family 7 175 1.6E-11 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS12580 c06c2d502012403a222a357677253d05 320 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 308 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 SMART SM00342 229 312 8.3E-33 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 312 6.9E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 296 6.9E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 Pfam PF12833 Helix-turn-helix domain 235 313 2.9E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS12580 c06c2d502012403a222a357677253d05 320 SUPERFAMILY SSF52317 7 194 1.89E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS12580 c06c2d502012403a222a357677253d05 320 Gene3D G3DSA:1.10.10.60 230 263 2.1E-9 T 28-03-2018 SMD44_RS40450 97c7dff0617d9414a90525d4cbb1d66c 186 SUPERFAMILY SSF46689 4 62 4.62E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS40450 97c7dff0617d9414a90525d4cbb1d66c 186 Gene3D G3DSA:1.10.10.60 1 46 5.6E-8 T 28-03-2018 SMD44_RS40450 97c7dff0617d9414a90525d4cbb1d66c 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 48 7.9E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS40450 97c7dff0617d9414a90525d4cbb1d66c 186 Gene3D G3DSA:1.10.357.10 47 180 1.0E-19 T 28-03-2018 SMD44_RS40450 97c7dff0617d9414a90525d4cbb1d66c 186 SUPERFAMILY SSF48498 72 176 2.4E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS36455 2501c29fea805b1ed739f3d41f3c086d 141 SMART SM00823 Phosphopantetheine attachment site 18 90 1.1E-25 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36455 2501c29fea805b1ed739f3d41f3c086d 141 ProSitePatterns PS00012 Phosphopantetheine attachment site. 45 60 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36455 2501c29fea805b1ed739f3d41f3c086d 141 SMART SM01294 19 86 0.0046 T 28-03-2018 SMD44_RS36455 2501c29fea805b1ed739f3d41f3c086d 141 SUPERFAMILY SSF47336 12 99 1.44E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36455 2501c29fea805b1ed739f3d41f3c086d 141 Pfam PF00550 Phosphopantetheine attachment site 20 86 3.0E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36455 2501c29fea805b1ed739f3d41f3c086d 141 Gene3D G3DSA:1.10.1200.10 11 130 3.9E-21 T 28-03-2018 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 Pfam PF00925 GTP cyclohydrolase II 212 377 4.9E-72 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 SUPERFAMILY SSF55821 4 205 1.56E-80 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 4 400 53.693 T 28-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 213 401 1.7E-74 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 Gene3D G3DSA:3.90.870.10 2 216 1.0E-93 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 SUPERFAMILY SSF142695 209 380 2.48E-68 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 6 203 7.8E-73 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 3 207 37.879 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 PIRSF PIRSF001259 4 410 1.3E-175 T 28-03-2018 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 208 404 41.39 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD44_RS07015 068852a3696a220cd1f2a7f98c4affc6 416 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 10 202 5.4E-83 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS27950 6629063946f552da7b897f5ce0f4adde 298 Pfam PF12697 Alpha/beta hydrolase family 41 282 6.1E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS27950 6629063946f552da7b897f5ce0f4adde 298 SUPERFAMILY SSF53474 31 289 1.51E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27950 6629063946f552da7b897f5ce0f4adde 298 Gene3D G3DSA:3.40.50.1820 4 295 2.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS29780 e26dcb2d028083d20a538a2a2f6c25e9 319 Gene3D G3DSA:3.90.180.10 5 146 1.2E-41 T 28-03-2018 SMD44_RS29780 e26dcb2d028083d20a538a2a2f6c25e9 319 Pfam PF13602 Zinc-binding dehydrogenase 194 316 8.7E-27 T 28-03-2018 SMD44_RS29780 e26dcb2d028083d20a538a2a2f6c25e9 319 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 99 2.1E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS29780 e26dcb2d028083d20a538a2a2f6c25e9 319 SMART SM00829 18 316 4.3E-46 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS29780 e26dcb2d028083d20a538a2a2f6c25e9 319 Gene3D G3DSA:3.40.50.720 147 302 8.4E-34 T 28-03-2018 SMD44_RS29780 e26dcb2d028083d20a538a2a2f6c25e9 319 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 152 173 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS29780 e26dcb2d028083d20a538a2a2f6c25e9 319 SUPERFAMILY SSF50129 6 157 6.85E-39 T 28-03-2018 IPR011032 GroES-like SMD44_RS29780 e26dcb2d028083d20a538a2a2f6c25e9 319 SUPERFAMILY SSF51735 124 251 4.38E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 SUPERFAMILY SSF56634 55 355 5.76E-47 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 Pfam PF03098 Animal haem peroxidase 435 941 1.9E-105 T 28-03-2018 IPR019791 Haem peroxidase, animal type SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 Gene3D G3DSA:2.40.180.10 12 358 4.5E-56 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 Gene3D G3DSA:1.10.640.10 396 947 2.3E-99 T 28-03-2018 IPR019791 Haem peroxidase, animal type SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 Pfam PF00199 Catalase 81 160 3.0E-4 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 SUPERFAMILY SSF48113 434 686 6.95E-110 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 SUPERFAMILY SSF48113 715 959 6.95E-110 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 PRINTS PR00457 Animal haem peroxidase signature 652 678 3.5E-9 T 28-03-2018 IPR019791 Haem peroxidase, animal type SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 PRINTS PR00457 Animal haem peroxidase signature 852 872 3.5E-9 T 28-03-2018 IPR019791 Haem peroxidase, animal type SMD44_RS08430 d20d0ea95f853cf824df8edbf5895e08 966 PRINTS PR00457 Animal haem peroxidase signature 627 647 3.5E-9 T 28-03-2018 IPR019791 Haem peroxidase, animal type SMD44_RS37145 4e5fe60c56ed2089b6547bf4f3494c9c 425 Gene3D G3DSA:3.20.20.80 17 347 3.4E-35 T 28-03-2018 SMD44_RS37145 4e5fe60c56ed2089b6547bf4f3494c9c 425 SUPERFAMILY SSF51445 30 342 1.98E-35 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS02825 14048ca1230538497ae0dff133974446 580 Gene3D G3DSA:3.90.76.10 87 219 6.3E-30 T 28-03-2018 SMD44_RS02825 14048ca1230538497ae0dff133974446 580 SUPERFAMILY SSF53850 47 556 9.41E-92 T 28-03-2018 SMD44_RS02825 14048ca1230538497ae0dff133974446 580 Gene3D G3DSA:3.10.105.10 334 543 4.0E-44 T 28-03-2018 SMD44_RS02825 14048ca1230538497ae0dff133974446 580 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 480 2.9E-70 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS02825 14048ca1230538497ae0dff133974446 580 PIRSF PIRSF002741 3 565 2.3E-63 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS02825 14048ca1230538497ae0dff133974446 580 Gene3D G3DSA:3.40.190.10 222 333 1.1E-14 T 28-03-2018 SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 Gene3D G3DSA:2.40.10.10 75 125 9.1E-13 T 28-03-2018 SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 Gene3D G3DSA:2.40.10.10 46 74 3.1E-11 T 28-03-2018 SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 SMART SM00020 45 239 4.7E-15 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 70 85 2.1E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 115 129 2.1E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 197 209 2.1E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 SUPERFAMILY SSF50494 18 243 4.52E-35 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 Pfam PF00089 Trypsin 53 239 6.7E-26 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS02265 4d0c56f198a63a04f98735de81f9bd77 245 Gene3D G3DSA:2.40.10.10 126 244 6.2E-17 T 28-03-2018 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 168 6.7E-54 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 SUPERFAMILY SSF47807 169 277 8.97E-28 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 SUPERFAMILY SSF53098 309 478 4.4E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 SMART SM00474 306 477 6.3E-6 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 613 635 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 636 651 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 804 820 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 834 847 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 682 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 713 738 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 750 761 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 689 702 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 772 783 3.2E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 SMART SM00482 644 851 3.8E-111 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Gene3D G3DSA:3.30.420.10 278 446 1.4E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 SUPERFAMILY SSF56672 484 885 7.78E-136 T 28-03-2018 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 TIGRFAM TIGR00593 pola: DNA polymerase I 1 886 2.4E-290 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Gene3D G3DSA:3.30.70.370 713 888 1.1E-43 T 28-03-2018 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Gene3D G3DSA:3.30.70.370 612 709 1.4E-15 T 28-03-2018 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 170 263 2.7E-26 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Gene3D G3DSA:1.20.1060.10 447 611 2.2E-41 T 28-03-2018 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Gene3D G3DSA:3.40.50.1010 1 181 1.2E-66 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Pfam PF00476 DNA polymerase family A 509 884 1.3E-138 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 SMART SM00475 1 259 7.6E-140 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 Gene3D G3DSA:1.10.150.20 182 259 2.2E-24 T 28-03-2018 SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 SUPERFAMILY SSF88723 1 168 2.43E-52 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS10515 845fd18f7e42fe4c3b7514a304362712 888 SMART SM00279 171 206 3.7E-14 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SMD44_RS04225 896855a381bfad2b9a2e879626302520 145 Pfam PF10686 Protein of unknown function (DUF2493) 4 74 1.6E-11 T 28-03-2018 IPR019627 Mycobacteriophage D29, Gp61 SMD44_RS04225 896855a381bfad2b9a2e879626302520 145 Gene3D G3DSA:3.40.50.450 2 144 4.3E-6 T 28-03-2018 SMD44_RS27250 60c1c0b54f6853879da2db2fb55905fb 472 Pfam PF02447 GntP family permease 11 470 1.4E-128 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD44_RS27250 60c1c0b54f6853879da2db2fb55905fb 472 PIRSF PIRSF002746 5 472 2.9E-166 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD44_RS27250 60c1c0b54f6853879da2db2fb55905fb 472 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 11 471 5.1E-117 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD44_RS10135 8c98cdc4cd55393f84bd30372637b267 329 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 2.1E-111 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like SMD44_RS10135 8c98cdc4cd55393f84bd30372637b267 329 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 6.7E-24 T 28-03-2018 SMD44_RS10135 8c98cdc4cd55393f84bd30372637b267 329 Pfam PF02650 WhiA C-terminal HTH domain 221 303 1.3E-19 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal SMD44_RS10135 8c98cdc4cd55393f84bd30372637b267 329 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 3.8E-25 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain SMD44_RS10135 8c98cdc4cd55393f84bd30372637b267 329 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.735 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 SMD44_RS26140 deb002baa58366b2af74f8116e65e234 304 SUPERFAMILY SSF53850 99 299 8.69E-37 T 28-03-2018 SMD44_RS26140 deb002baa58366b2af74f8116e65e234 304 Gene3D G3DSA:3.40.190.10 186 272 3.8E-16 T 28-03-2018 SMD44_RS26140 deb002baa58366b2af74f8116e65e234 304 Gene3D G3DSA:1.10.10.10 2 112 5.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26140 deb002baa58366b2af74f8116e65e234 304 SUPERFAMILY SSF46785 10 86 1.32E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26140 deb002baa58366b2af74f8116e65e234 304 Pfam PF03466 LysR substrate binding domain 99 299 1.9E-21 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS26140 deb002baa58366b2af74f8116e65e234 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 8.2E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26140 deb002baa58366b2af74f8116e65e234 304 Gene3D G3DSA:3.40.190.10 113 185 4.0E-12 T 28-03-2018 SMD44_RS10535 6ebfeef51fb84fc94eb1c1487a0c7a5d 309 Gene3D G3DSA:1.10.3470.10 1 298 3.5E-51 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS10535 6ebfeef51fb84fc94eb1c1487a0c7a5d 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 1.2E-48 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS18930 ff2119b0e647062e3d7c006ffe1be8fe 158 Pfam PF00583 Acetyltransferase (GNAT) family 22 135 4.7E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS18930 ff2119b0e647062e3d7c006ffe1be8fe 158 Gene3D G3DSA:3.40.630.30 1 86 9.7E-23 T 28-03-2018 SMD44_RS18930 ff2119b0e647062e3d7c006ffe1be8fe 158 Gene3D G3DSA:3.40.630.30 87 149 1.3E-17 T 28-03-2018 SMD44_RS18930 ff2119b0e647062e3d7c006ffe1be8fe 158 SUPERFAMILY SSF55729 1 150 9.09E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS43055 4271c9567969b8719626ef90140d4c7a 674 Gene3D G3DSA:3.10.350.10 157 224 4.6E-9 T 28-03-2018 SMD44_RS43055 4271c9567969b8719626ef90140d4c7a 674 Pfam PF01476 LysM domain 164 219 3.9E-4 T 28-03-2018 IPR018392 LysM domain SMD44_RS43055 4271c9567969b8719626ef90140d4c7a 674 Pfam PF01476 LysM domain 238 293 0.0083 T 28-03-2018 IPR018392 LysM domain SMD44_RS43055 4271c9567969b8719626ef90140d4c7a 674 SMART SM00257 163 219 5.4 T 28-03-2018 IPR018392 LysM domain SMD44_RS43055 4271c9567969b8719626ef90140d4c7a 674 SMART SM00257 237 293 0.02 T 28-03-2018 IPR018392 LysM domain SMD44_RS43055 4271c9567969b8719626ef90140d4c7a 674 Gene3D G3DSA:3.10.350.10 232 309 8.3E-11 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF52151 11 135 6.8E-69 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF52151 199 298 6.8E-69 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Pfam PF00550 Phosphopantetheine attachment site 1246 1311 1.4E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Gene3D G3DSA:1.10.1200.10 1249 1318 4.9E-17 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Gene3D G3DSA:3.40.50.720 916 1248 5.9E-50 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 956 1136 1.4E-62 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Gene3D G3DSA:3.40.366.10 192 316 3.1E-27 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Pfam PF00698 Acyl transferase domain 12 327 5.2E-84 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SMART SM00823 Phosphopantetheine attachment site 1243 1315 1.9E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SMART SM00824 Thioesterase 1435 1654 3.0E-85 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1270 1285 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF55048 133 198 9.16E-13 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Pfam PF08659 KR domain 956 1135 4.3E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SMART SM00826 376 543 4.0E-87 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 14 309 7.9E-114 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SMART SM01294 1244 1311 0.0019 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF51735 953 1172 1.04E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Pfam PF14765 Polyketide synthase dehydratase 376 657 2.5E-57 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Gene3D G3DSA:3.30.70.250 142 191 6.2E-18 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Gene3D G3DSA:3.10.129.10 378 501 7.9E-9 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF47336 1237 1330 6.88E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Gene3D G3DSA:3.40.50.1820 1377 1657 2.3E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Gene3D G3DSA:3.40.366.10 11 141 2.0E-38 T 28-03-2018 SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF53474 1273 1311 6.54E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF53474 1410 1656 6.54E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF51735 879 916 7.87E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 SUPERFAMILY SSF51735 664 845 7.87E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36895 1432b43c3908911082e73d60da910a23 1657 Pfam PF00975 Thioesterase domain 1445 1653 2.9E-20 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS30690 84bfd72372f99bf46232519c2fdc0136 251 SUPERFAMILY SSF53335 3 234 1.17E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS30690 84bfd72372f99bf46232519c2fdc0136 251 Gene3D G3DSA:3.40.50.150 1 251 2.2E-44 T 28-03-2018 SMD44_RS30690 84bfd72372f99bf46232519c2fdc0136 251 Pfam PF04672 S-adenosyl methyltransferase 2 238 3.1E-92 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS30690 84bfd72372f99bf46232519c2fdc0136 251 PIRSF PIRSF017393 1 251 7.9E-91 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS07170 969de02361302a87201b312c7188539a 228 SUPERFAMILY SSF51366 3 212 7.65E-65 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD44_RS07170 969de02361302a87201b312c7188539a 228 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMD44_RS07170 969de02361302a87201b312c7188539a 228 PIRSF PIRSF001461 1 224 1.7E-95 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMD44_RS07170 969de02361302a87201b312c7188539a 228 Gene3D G3DSA:3.20.20.70 1 216 1.2E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS07170 969de02361302a87201b312c7188539a 228 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMD44_RS07170 969de02361302a87201b312c7188539a 228 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 199 1.5E-77 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMD44_RS07170 969de02361302a87201b312c7188539a 228 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 212 1.4E-80 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMD44_RS19175 fb43ca74a3cad5657a72c6a98334665f 224 Gene3D G3DSA:1.10.357.10 76 222 5.9E-27 T 28-03-2018 SMD44_RS19175 fb43ca74a3cad5657a72c6a98334665f 224 ProSitePatterns PS01081 TetR-type HTH domain signature. 43 74 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS19175 fb43ca74a3cad5657a72c6a98334665f 224 Gene3D G3DSA:1.10.10.60 2 75 3.9E-19 T 28-03-2018 SMD44_RS19175 fb43ca74a3cad5657a72c6a98334665f 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 75 1.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19175 fb43ca74a3cad5657a72c6a98334665f 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 7.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19175 fb43ca74a3cad5657a72c6a98334665f 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 7.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19175 fb43ca74a3cad5657a72c6a98334665f 224 SUPERFAMILY SSF46689 20 98 3.94E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS08310 7a2cba3f0dd0822ffb0161a1b1ce4650 228 SUPERFAMILY SSF53254 1 210 5.57E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS08310 7a2cba3f0dd0822ffb0161a1b1ce4650 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 202 1.5E-47 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS08310 7a2cba3f0dd0822ffb0161a1b1ce4650 228 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 203 2.1E-96 T 28-03-2018 IPR022492 Phosphomutase MSMEG4193, putative SMD44_RS08310 7a2cba3f0dd0822ffb0161a1b1ce4650 228 Gene3D G3DSA:3.40.50.1240 1 214 1.3E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS08310 7a2cba3f0dd0822ffb0161a1b1ce4650 228 SMART SM00855 3 162 9.6E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS31735 f52498dd8fd2627a555ecadaf53f76f7 194 Gene3D G3DSA:3.10.129.10 12 165 1.1E-28 T 28-03-2018 SMD44_RS31735 f52498dd8fd2627a555ecadaf53f76f7 194 SUPERFAMILY SSF54637 20 159 1.25E-32 T 28-03-2018 IPR029069 HotDog domain SMD44_RS31735 f52498dd8fd2627a555ecadaf53f76f7 194 Pfam PF03061 Thioesterase superfamily 75 138 1.2E-8 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMD44_RS30685 16a3372d7b438e7daf42716a33b3ef2e 223 Gene3D G3DSA:3.40.50.720 1 197 7.1E-24 T 28-03-2018 SMD44_RS30685 16a3372d7b438e7daf42716a33b3ef2e 223 SUPERFAMILY SSF51735 1 201 8.94E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS30685 16a3372d7b438e7daf42716a33b3ef2e 223 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 93 6.7E-14 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMD44_RS33355 45d2cb27e44bb1a217e886f56228565b 135 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 7 135 2.5E-28 T 28-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMD44_RS33355 45d2cb27e44bb1a217e886f56228565b 135 Pfam PF00576 HIUase/Transthyretin family 9 134 2.7E-33 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD44_RS33355 45d2cb27e44bb1a217e886f56228565b 135 SUPERFAMILY SSF49472 4 135 9.16E-27 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD44_RS33355 45d2cb27e44bb1a217e886f56228565b 135 ProSitePatterns PS00768 Transthyretin signature 1. 12 27 - T 28-03-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD44_RS33355 45d2cb27e44bb1a217e886f56228565b 135 Gene3D G3DSA:2.60.40.180 1 135 3.7E-39 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD44_RS39585 2cf2197a9a10e791a66f5ed52f22fa63 336 Gene3D G3DSA:3.40.50.720 1 185 8.2E-43 T 28-03-2018 SMD44_RS39585 2cf2197a9a10e791a66f5ed52f22fa63 336 Gene3D G3DSA:3.90.25.10 186 332 1.6E-44 T 28-03-2018 SMD44_RS39585 2cf2197a9a10e791a66f5ed52f22fa63 336 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 321 1.4E-126 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 SMD44_RS39585 2cf2197a9a10e791a66f5ed52f22fa63 336 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 305 6.8E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS39585 2cf2197a9a10e791a66f5ed52f22fa63 336 SUPERFAMILY SSF51735 1 322 1.73E-98 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 Pfam PF04055 Radical SAM superfamily 15 166 1.6E-21 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 Pfam PF13186 Iron-sulfur cluster-binding domain 238 304 2.7E-7 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 Gene3D G3DSA:3.20.20.70 4 298 9.5E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 5 349 5.6E-143 T 28-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 245 331 3.5E-10 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 Pfam PF13353 4Fe-4S single cluster domain 16 97 1.3E-5 T 28-03-2018 SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 SMART SM00729 9 209 8.7E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 15 26 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 PIRSF PIRSF037420 1 350 1.2E-92 T 28-03-2018 SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 364 150.248 T 28-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 SMD44_RS34570 420f4fa24ae53d4dbf14720f6f6e7c31 364 SUPERFAMILY SSF102114 7 313 5.62E-67 T 28-03-2018 SMD44_RS10725 dd8df2ca6f3937874051dd088f1f5b45 443 Pfam PF03747 ADP-ribosylglycohydrolase 35 364 4.6E-33 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10725 dd8df2ca6f3937874051dd088f1f5b45 443 Gene3D G3DSA:1.10.4080.10 24 402 1.8E-46 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10725 dd8df2ca6f3937874051dd088f1f5b45 443 SUPERFAMILY SSF101478 31 397 3.14E-35 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 171 405 1.4E-84 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 PIRSF PIRSF036426 155 409 2.9E-93 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 PIRSF PIRSF036426 5 160 8.3E-29 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 9 132 2.7E-18 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 Pfam PF13241 Putative NAD(P)-binding 12 119 4.2E-17 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 Gene3D G3DSA:3.30.950.10 294 408 3.7E-35 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 Gene3D G3DSA:3.40.1010.10 170 293 2.0E-35 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 Gene3D G3DSA:3.40.50.720 7 134 1.0E-17 T 28-03-2018 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 249 282 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 SUPERFAMILY SSF51735 8 110 6.4E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 SUPERFAMILY SSF53790 166 405 8.37E-72 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS07655 9e1caf12dae91c294b15f63700a63ddd 411 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 171 382 7.3E-49 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS10930 7fe07f962d0a9dc26dd15727d262ed72 564 Pfam PF09423 PhoD-like phosphatase 171 528 2.1E-116 T 28-03-2018 IPR018946 Alkaline phosphatase D-related SMD44_RS10930 7fe07f962d0a9dc26dd15727d262ed72 564 Gene3D G3DSA:3.60.21.10 168 561 9.6E-45 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS10930 7fe07f962d0a9dc26dd15727d262ed72 564 Gene3D G3DSA:2.60.40.380 55 162 1.0E-7 T 28-03-2018 SMD44_RS10930 7fe07f962d0a9dc26dd15727d262ed72 564 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 59 158 2.1E-31 T 28-03-2018 IPR032093 Phospholipase D, N-terminal SMD44_RS10930 7fe07f962d0a9dc26dd15727d262ed72 564 SUPERFAMILY SSF56300 167 533 2.28E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS18125 d258bac966f2e3b2f0a131ea1f008028 373 Pfam PF13490 Putative zinc-finger 4 33 3.3E-5 T 28-03-2018 IPR027383 Putative zinc-finger SMD44_RS18125 d258bac966f2e3b2f0a131ea1f008028 373 SUPERFAMILY SSF109854 73 248 5.95E-14 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS18125 d258bac966f2e3b2f0a131ea1f008028 373 Gene3D G3DSA:1.20.120.450 74 248 6.8E-30 T 28-03-2018 SMD44_RS01075 87e6d588bae9832c379c1ace24128956 151 Gene3D G3DSA:3.40.50.360 4 133 2.0E-25 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS01075 87e6d588bae9832c379c1ace24128956 151 PIRSF PIRSF005087 2 138 9.8E-54 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI SMD44_RS01075 87e6d588bae9832c379c1ace24128956 151 Hamap MF_00128 Protein NrdI [nrdI]. 3 134 35.28 T 28-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial SMD44_RS01075 87e6d588bae9832c379c1ace24128956 151 Pfam PF07972 NrdI Flavodoxin like 5 124 1.1E-46 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI SMD44_RS01075 87e6d588bae9832c379c1ace24128956 151 TIGRFAM TIGR00333 nrdI: nrdI protein 5 132 9.7E-48 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI SMD44_RS01075 87e6d588bae9832c379c1ace24128956 151 SUPERFAMILY SSF52218 4 133 2.81E-24 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS34575 037b43015e48626d4cd7b76d7ad51bac 347 SUPERFAMILY SSF48208 10 343 9.35E-66 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS34575 037b43015e48626d4cd7b76d7ad51bac 347 Gene3D G3DSA:1.50.10.10 4 346 3.7E-69 T 28-03-2018 SMD44_RS34575 037b43015e48626d4cd7b76d7ad51bac 347 Pfam PF07470 Glycosyl Hydrolase Family 88 16 339 1.3E-75 T 28-03-2018 IPR010905 Glycosyl hydrolase, family 88 SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 Gene3D G3DSA:1.10.10.10 44 105 1.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 SUPERFAMILY SSF53383 114 480 9.89E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 Gene3D G3DSA:3.40.640.10 141 385 4.2E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 Pfam PF00155 Aminotransferase class I and II 139 438 8.0E-15 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 77 9.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 77 93 9.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 SUPERFAMILY SSF46785 41 111 5.99E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 Pfam PF00392 Bacterial regulatory proteins, gntR family 44 103 9.6E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 Gene3D G3DSA:3.90.1150.10 386 481 7.8E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS26195 2b93fb1ebe35a6d254b046efe1a5002a 481 SMART SM00345 44 103 6.7E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS38765 96d5cd095163c112a5ebc7c04d52e57c 229 SMART SM00014 78 206 0.0044 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS38765 96d5cd095163c112a5ebc7c04d52e57c 229 Gene3D G3DSA:1.20.144.10 54 229 3.4E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS38765 96d5cd095163c112a5ebc7c04d52e57c 229 Pfam PF01569 PAP2 superfamily 90 211 1.6E-11 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS38765 96d5cd095163c112a5ebc7c04d52e57c 229 SUPERFAMILY SSF48317 15 213 4.45E-25 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS29725 139c3b29eab30c29aa80c8ea21a0bbab 355 Pfam PF03601 Conserved hypothetical protein 698 27 332 1.7E-65 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SMD44_RS35860 c9a8968337d22364a6db601b7b6fe8c3 276 Gene3D G3DSA:3.40.50.300 17 272 1.1E-16 T 28-03-2018 SMD44_RS35860 c9a8968337d22364a6db601b7b6fe8c3 276 SUPERFAMILY SSF52540 16 83 1.88E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS35860 c9a8968337d22364a6db601b7b6fe8c3 276 SUPERFAMILY SSF52540 117 198 1.88E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS35860 c9a8968337d22364a6db601b7b6fe8c3 276 Pfam PF13481 AAA domain 31 191 4.7E-10 T 28-03-2018 SMD44_RS33625 9ef97a47c2796bdf18b17f3abbda32bd 264 Pfam PF00005 ABC transporter 17 171 5.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS33625 9ef97a47c2796bdf18b17f3abbda32bd 264 SMART SM00382 26 218 4.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS33625 9ef97a47c2796bdf18b17f3abbda32bd 264 Gene3D G3DSA:3.40.50.300 1 255 2.9E-48 T 28-03-2018 SMD44_RS33625 9ef97a47c2796bdf18b17f3abbda32bd 264 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS33625 9ef97a47c2796bdf18b17f3abbda32bd 264 SUPERFAMILY SSF52540 2 229 3.48E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 SUPERFAMILY SSF53067 155 347 8.72E-16 T 28-03-2018 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 Pfam PF00012 Hsp70 protein 76 341 1.0E-27 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 SUPERFAMILY SSF53067 13 153 1.55E-14 T 28-03-2018 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 SUPERFAMILY SSF48452 524 653 1.25E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 Gene3D G3DSA:1.25.40.10 405 660 1.6E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 Gene3D G3DSA:3.30.420.40 161 325 7.8E-10 T 28-03-2018 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 PRINTS PR00301 70kDa heat shock protein signature 304 320 1.9E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 PRINTS PR00301 70kDa heat shock protein signature 11 24 1.9E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 PRINTS PR00301 70kDa heat shock protein signature 108 128 1.9E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS32575 e8c339ed64ab8b4be339e86eee30903a 667 Gene3D G3DSA:3.30.420.40 3 160 1.5E-18 T 28-03-2018 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 Gene3D G3DSA:1.20.140.10 218 382 4.2E-60 T 28-03-2018 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 PIRSF PIRSF016578 3 380 1.9E-20 T 28-03-2018 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 Gene3D G3DSA:1.10.540.10 1 120 7.4E-40 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 SUPERFAMILY SSF47203 228 379 5.8E-57 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 7.5E-29 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 7.2E-36 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 4.9E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 Gene3D G3DSA:2.40.110.10 121 217 1.8E-40 T 28-03-2018 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS08585 04bf6acd9f38fa7c77fa53c60023f080 383 SUPERFAMILY SSF56645 2 241 4.58E-86 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS10660 36396ab668d16319ddfc2da3a3b6dc7c 167 Gene3D G3DSA:1.10.10.10 1 28 0.12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10660 36396ab668d16319ddfc2da3a3b6dc7c 167 SMART SM00347 44 144 5.3E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS10660 36396ab668d16319ddfc2da3a3b6dc7c 167 Gene3D G3DSA:1.10.10.10 29 165 6.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10660 36396ab668d16319ddfc2da3a3b6dc7c 167 SUPERFAMILY SSF46785 31 156 8.63E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10660 36396ab668d16319ddfc2da3a3b6dc7c 167 Pfam PF01047 MarR family 51 109 2.9E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 Pfam PF07501 G5 domain 251 323 1.5E-22 T 28-03-2018 IPR011098 G5 domain SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 Gene3D G3DSA:1.10.530.10 319 409 1.9E-28 T 28-03-2018 SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 Gene3D G3DSA:2.20.230.10 245 318 8.6E-23 T 28-03-2018 SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 SUPERFAMILY SSF53955 332 408 1.37E-22 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 SMART SM01208 246 324 2.8E-26 T 28-03-2018 IPR011098 G5 domain SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 Pfam PF03990 Domain of unknown function (DUF348) 136 166 9.7E-8 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 Pfam PF03990 Domain of unknown function (DUF348) 193 231 6.1E-10 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 Pfam PF03990 Domain of unknown function (DUF348) 79 117 4.9E-13 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMD44_RS17075 5190fbfb833efb976bba30334e263839 409 Pfam PF06737 Transglycosylase-like domain 333 405 1.6E-22 T 28-03-2018 IPR010618 Transglycosylase-like SMD44_RS29460 17bfe6ad0d2e815e2007e770483593a5 129 SUPERFAMILY SSF54593 4 127 5.91E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS29460 17bfe6ad0d2e815e2007e770483593a5 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 7.8E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS29460 17bfe6ad0d2e815e2007e770483593a5 129 Gene3D G3DSA:3.10.180.10 1 129 3.0E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS03700 b170efaeaac4762f52a67cda096e1649 332 SUPERFAMILY SSF161098 107 318 8.11E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS03700 b170efaeaac4762f52a67cda096e1649 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 330 4.4E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS03700 b170efaeaac4762f52a67cda096e1649 332 Gene3D G3DSA:1.10.3720.10 2 319 1.9E-38 T 28-03-2018 SMD44_RS16280 bfaaa64e31f03fe439174018221536c2 249 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 21 124 3.6E-22 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMD44_RS16280 bfaaa64e31f03fe439174018221536c2 249 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 22 119 4.2E-19 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMD44_RS16280 bfaaa64e31f03fe439174018221536c2 249 Gene3D G3DSA:3.30.160.100 19 126 2.6E-23 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMD44_RS16280 bfaaa64e31f03fe439174018221536c2 249 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 20 230 22.098 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid SMD44_RS16280 bfaaa64e31f03fe439174018221536c2 249 SUPERFAMILY SSF69754 22 129 3.14E-22 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMD44_RS16280 bfaaa64e31f03fe439174018221536c2 249 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 173 226 1.3E-21 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal SMD44_RS16910 e6411ba0e199bbcc8640218d63ab5257 329 SUPERFAMILY SSF160631 155 302 2.22E-16 T 28-03-2018 SMD44_RS16910 e6411ba0e199bbcc8640218d63ab5257 329 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 164 278 2.7E-8 T 28-03-2018 IPR018958 Knr4/Smi1-like domain SMD44_RS16910 e6411ba0e199bbcc8640218d63ab5257 329 SMART SM00860 163 301 9.4E-5 T 28-03-2018 IPR018958 Knr4/Smi1-like domain SMD44_RS16910 e6411ba0e199bbcc8640218d63ab5257 329 Gene3D G3DSA:3.40.1580.10 147 306 5.2E-18 T 28-03-2018 SMD44_RS16910 e6411ba0e199bbcc8640218d63ab5257 329 Pfam PF14414 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 99 134 1.2E-11 T 28-03-2018 IPR032869 WHH domain-containing protein SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 6.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 6.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 6.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 SMART SM00421 145 202 1.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 Gene3D G3DSA:3.40.50.2300 3 141 6.1E-26 T 28-03-2018 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 SMART SM00448 4 118 1.4E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 Gene3D G3DSA:1.10.10.10 147 208 3.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 Pfam PF00072 Response regulator receiver domain 6 116 7.5E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 SUPERFAMILY SSF52172 3 124 1.42E-24 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 SUPERFAMILY SSF46894 140 208 5.1E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS19835 0720e9aaf67a0313c93a01461ee7e53d 257 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 1.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 Gene3D G3DSA:3.40.50.2300 13 138 8.8E-37 T 28-03-2018 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 219 7.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 5.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 5.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 5.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 Gene3D G3DSA:1.10.10.10 139 228 1.3E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 SMART SM00448 14 127 2.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 SUPERFAMILY SSF46894 155 225 5.1E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 SUPERFAMILY SSF52172 13 144 7.83E-35 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 Pfam PF00072 Response regulator receiver domain 16 128 5.8E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS37225 b1526e2c5533088d5fa2740dffb12cc5 229 SMART SM00421 162 219 3.9E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS35985 3450b85b1b3916625f61f99cbeb2c301 284 Gene3D G3DSA:3.40.50.300 27 263 6.4E-66 T 28-03-2018 SMD44_RS35985 3450b85b1b3916625f61f99cbeb2c301 284 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS35985 3450b85b1b3916625f61f99cbeb2c301 284 Pfam PF00005 ABC transporter 51 190 7.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS35985 3450b85b1b3916625f61f99cbeb2c301 284 SMART SM00382 60 241 3.1E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS35985 3450b85b1b3916625f61f99cbeb2c301 284 SUPERFAMILY SSF52540 34 248 2.18E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14840 6790ea4bd92a82087abfb3e97326413b 312 SUPERFAMILY SSF46785 28 138 2.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14840 6790ea4bd92a82087abfb3e97326413b 312 SUPERFAMILY SSF55729 149 289 4.8E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS14840 6790ea4bd92a82087abfb3e97326413b 312 Gene3D G3DSA:1.10.10.10 2 145 3.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14840 6790ea4bd92a82087abfb3e97326413b 312 Pfam PF00583 Acetyltransferase (GNAT) family 189 283 2.8E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS14840 6790ea4bd92a82087abfb3e97326413b 312 SMART SM00347 23 123 5.1E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS14840 6790ea4bd92a82087abfb3e97326413b 312 Pfam PF12802 MarR family 31 87 1.1E-12 T 28-03-2018 SMD44_RS14840 6790ea4bd92a82087abfb3e97326413b 312 Gene3D G3DSA:3.40.630.30 146 304 6.9E-25 T 28-03-2018 SMD44_RS10255 c4977e052104d4c9dfb5db286e55dce7 300 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 50 292 1.6E-43 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD44_RS10255 c4977e052104d4c9dfb5db286e55dce7 300 Gene3D G3DSA:3.20.20.190 24 300 1.2E-72 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS10255 c4977e052104d4c9dfb5db286e55dce7 300 SUPERFAMILY SSF51695 44 297 3.92E-69 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS12120 7ec5b225d033e7c4a479cffa294cb52d 154 Gene3D G3DSA:2.60.40.1260 7 151 4.2E-20 T 28-03-2018 IPR001322 Lamin Tail Domain SMD44_RS12120 7ec5b225d033e7c4a479cffa294cb52d 154 SUPERFAMILY SSF74853 54 145 4.19E-15 T 28-03-2018 IPR001322 Lamin Tail Domain SMD44_RS12120 7ec5b225d033e7c4a479cffa294cb52d 154 Pfam PF00932 Lamin Tail Domain 38 144 2.2E-21 T 28-03-2018 IPR001322 Lamin Tail Domain SMD44_RS28040 498f6ed951c664aa2372eb3d609ea901 523 SUPERFAMILY SSF53474 209 272 1.29E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28040 498f6ed951c664aa2372eb3d609ea901 523 SUPERFAMILY SSF53474 108 166 1.29E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28040 498f6ed951c664aa2372eb3d609ea901 523 SUPERFAMILY SSF53474 328 482 1.29E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28040 498f6ed951c664aa2372eb3d609ea901 523 Gene3D G3DSA:3.40.50.1820 94 511 2.4E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28040 498f6ed951c664aa2372eb3d609ea901 523 Pfam PF08386 TAP-like protein 416 521 1.7E-31 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD44_RS16485 db6b1188b22215684510f2765e301591 332 Gene3D G3DSA:3.90.550.10 1 237 1.5E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16485 db6b1188b22215684510f2765e301591 332 Pfam PF00535 Glycosyl transferase family 2 1 128 1.3E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS16485 db6b1188b22215684510f2765e301591 332 SUPERFAMILY SSF53448 1 238 5.63E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS21770 5c17de0ae80f2e2007ffe05230a6218b 179 Pfam PF10759 Protein of unknown function (DUF2587) 29 162 1.3E-79 T 28-03-2018 IPR019695 Bacterial proteasome activator GO:0061136 SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 Gene3D G3DSA:1.10.10.10 6 103 2.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 Gene3D G3DSA:1.25.40.10 104 288 7.2E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 Gene3D G3DSA:1.25.40.10 658 1153 3.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 SMART SM00862 16 95 3.5E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 SUPERFAMILY SSF48452 99 264 1.57E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 SUPERFAMILY SSF52540 295 488 2.91E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 SUPERFAMILY SSF46894 8 95 1.53E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 SMART SM01043 102 250 1.1E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 Gene3D G3DSA:3.40.50.300 299 472 1.7E-13 T 28-03-2018 SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 Pfam PF03704 Bacterial transcriptional activator domain 102 250 8.9E-36 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS23485 e975d5e058d076253a5df19607fe0e96 1153 Pfam PF13191 AAA ATPase domain 299 444 6.3E-18 T 28-03-2018 SMD44_RS28515 f2c0b428b765b2268b96876d1f073ea2 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS28515 f2c0b428b765b2268b96876d1f073ea2 253 SUPERFAMILY SSF52540 4 248 3.51E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28515 f2c0b428b765b2268b96876d1f073ea2 253 SMART SM00382 29 226 9.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS28515 f2c0b428b765b2268b96876d1f073ea2 253 Pfam PF00005 ABC transporter 20 178 2.3E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS28515 f2c0b428b765b2268b96876d1f073ea2 253 Gene3D G3DSA:3.40.50.300 1 253 1.6E-75 T 28-03-2018 SMD44_RS28515 f2c0b428b765b2268b96876d1f073ea2 253 PIRSF PIRSF039085 1 253 4.4E-127 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMD44_RS22930 4f5665c68ed350b50873331431af809c 412 SUPERFAMILY SSF51556 13 42 2.1E-77 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS22930 4f5665c68ed350b50873331431af809c 412 SUPERFAMILY SSF51556 92 404 2.1E-77 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS22930 4f5665c68ed350b50873331431af809c 412 Pfam PF04909 Amidohydrolase 101 400 3.4E-49 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS22930 4f5665c68ed350b50873331431af809c 412 Gene3D G3DSA:3.20.20.140 7 403 1.4E-69 T 28-03-2018 SMD44_RS31330 1bf0ae323ac4175cf9e61a8498340f30 116 Pfam PF03780 Asp23 family, cell envelope-related function 6 115 4.6E-9 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 SMD44_RS35930 cf946ea9b658ba929d5e9b6a985fffd4 144 Pfam PF03259 Roadblock/LC7 domain 13 104 2.8E-23 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS35930 cf946ea9b658ba929d5e9b6a985fffd4 144 SMART SM00960 14 104 7.2E-23 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS35930 cf946ea9b658ba929d5e9b6a985fffd4 144 SUPERFAMILY SSF103196 8 133 6.54E-25 T 28-03-2018 SMD44_RS35930 cf946ea9b658ba929d5e9b6a985fffd4 144 Gene3D G3DSA:3.30.450.30 9 136 1.3E-37 T 28-03-2018 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Gene3D G3DSA:1.10.10.400 278 335 1.1E-21 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 722 0.0 T 28-03-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 SMART SM00322 579 643 7.6E-12 T 28-03-2018 IPR004087 K Homology domain GO:0003676 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Gene3D G3DSA:3.30.230.70 336 576 8.8E-49 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 SUPERFAMILY SSF54211 6 151 4.15E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 PIRSF PIRSF005499 7 741 1.6E-281 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 267 343 8.0E-18 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 SUPERFAMILY SSF54791 576 688 2.13E-19 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 SUPERFAMILY SSF55666 152 260 4.82E-29 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 9 725 26.861 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 SUPERFAMILY SSF54211 321 492 2.28E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Gene3D G3DSA:2.40.50.140 649 721 3.4E-17 T 28-03-2018 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Pfam PF00013 KH domain 583 639 5.2E-11 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Pfam PF00575 S1 RNA binding domain 648 718 6.5E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Gene3D G3DSA:3.30.230.70 18 277 8.5E-49 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 SMART SM00316 649 723 3.8E-18 T 28-03-2018 IPR022967 RNA-binding domain, S1 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 SUPERFAMILY SSF46915 264 344 1.41E-17 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 17 720 7.2E-260 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 SUPERFAMILY SSF55666 474 573 1.96E-23 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Gene3D G3DSA:3.30.1370.10 577 648 4.8E-14 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 1.8E-13 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS31035 b752a8a05e6b8865f4e21b19611ef099 741 Pfam PF01138 3' exoribonuclease family, domain 1 20 151 1.0E-17 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD44_RS32195 a08e564541e8270252e436730c484f1f 485 SUPERFAMILY SSF69318 66 225 7.19E-22 T 28-03-2018 SMD44_RS32195 a08e564541e8270252e436730c484f1f 485 SUPERFAMILY SSF69318 273 449 7.19E-22 T 28-03-2018 SMD44_RS32195 a08e564541e8270252e436730c484f1f 485 Gene3D G3DSA:2.130.10.130 254 460 4.3E-13 T 28-03-2018 SMD44_RS32195 a08e564541e8270252e436730c484f1f 485 Gene3D G3DSA:2.60.40.680 136 225 1.3E-5 T 28-03-2018 SMD44_RS32195 a08e564541e8270252e436730c484f1f 485 Gene3D G3DSA:2.60.40.680 39 135 3.0E-5 T 28-03-2018 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 SUPERFAMILY SSF55545 42 183 8.24E-28 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 Gene3D G3DSA:3.30.379.10 44 172 3.2E-23 T 28-03-2018 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 48 181 2.8E-19 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 SUPERFAMILY SSF51445 184 532 2.39E-113 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 178 195 6.9E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 467 483 6.9E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 485 502 6.9E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 136 156 6.9E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 314 332 6.9E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 207 228 6.9E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 266 283 6.9E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 336 349 6.9E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 184 503 6.9E-84 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS14995 9fc9709f19d9787655ca990407603c72 541 Gene3D G3DSA:3.20.20.80 173 536 6.7E-122 T 28-03-2018 SMD44_RS33915 dd7168eb81f1bed57e0df86bac1b534a 247 Pfam PF00005 ABC transporter 22 170 1.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS33915 dd7168eb81f1bed57e0df86bac1b534a 247 SMART SM00382 31 218 1.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS33915 dd7168eb81f1bed57e0df86bac1b534a 247 PIRSF PIRSF039085 3 246 4.4E-112 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMD44_RS33915 dd7168eb81f1bed57e0df86bac1b534a 247 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS33915 dd7168eb81f1bed57e0df86bac1b534a 247 Gene3D G3DSA:3.40.50.300 2 246 1.9E-78 T 28-03-2018 SMD44_RS33915 dd7168eb81f1bed57e0df86bac1b534a 247 SUPERFAMILY SSF52540 6 240 6.27E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25625 abf04988689f33afce7f3d28e318a550 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 1.0E-9 T 28-03-2018 SMD44_RS25625 abf04988689f33afce7f3d28e318a550 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25625 abf04988689f33afce7f3d28e318a550 37 Pfam PF00444 Ribosomal protein L36 1 37 2.5E-19 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25625 abf04988689f33afce7f3d28e318a550 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 2.0E-21 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25625 abf04988689f33afce7f3d28e318a550 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 18.06 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25625 abf04988689f33afce7f3d28e318a550 37 SUPERFAMILY SSF57840 1 37 2.22E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS37400 46f81ab79302807a9315629c4cadd9f3 116 Pfam PF01638 HxlR-like helix-turn-helix 20 107 6.3E-25 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS37400 46f81ab79302807a9315629c4cadd9f3 116 SUPERFAMILY SSF46785 9 111 3.34E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37400 46f81ab79302807a9315629c4cadd9f3 116 Gene3D G3DSA:1.10.10.10 18 116 2.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06920 8631c5f27da10744590bd7bd1a665aef 366 Pfam PF01636 Phosphotransferase enzyme family 85 284 7.0E-24 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS06920 8631c5f27da10744590bd7bd1a665aef 366 Gene3D G3DSA:3.90.1200.10 145 345 1.3E-14 T 28-03-2018 SMD44_RS06920 8631c5f27da10744590bd7bd1a665aef 366 SUPERFAMILY SSF56112 27 323 7.65E-32 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS06920 8631c5f27da10744590bd7bd1a665aef 366 Gene3D G3DSA:3.30.200.20 20 127 2.8E-19 T 28-03-2018 SMD44_RS39710 86deb970e7febfa78d118019163ed941 123 SUPERFAMILY SSF52091 11 114 1.0E-18 T 28-03-2018 IPR002645 STAS domain SMD44_RS39710 86deb970e7febfa78d118019163ed941 123 Pfam PF01740 STAS domain 12 107 5.4E-12 T 28-03-2018 IPR002645 STAS domain SMD44_RS39710 86deb970e7febfa78d118019163ed941 123 Gene3D G3DSA:3.30.750.24 4 121 1.9E-15 T 28-03-2018 IPR002645 STAS domain SMD44_RS39710 86deb970e7febfa78d118019163ed941 123 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 9 111 1.9E-16 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD44_RS21420 b189e518efd8654b2ad30df82f9b987d 232 SUPERFAMILY SSF63817 74 220 1.28E-29 T 28-03-2018 IPR023365 Sortase domain SMD44_RS21420 b189e518efd8654b2ad30df82f9b987d 232 Pfam PF04203 Sortase family 85 216 5.8E-28 T 28-03-2018 IPR005754 Sortase family SMD44_RS21420 b189e518efd8654b2ad30df82f9b987d 232 Gene3D G3DSA:2.40.260.10 35 231 1.5E-38 T 28-03-2018 IPR023365 Sortase domain SMD44_RS21420 b189e518efd8654b2ad30df82f9b987d 232 TIGRFAM TIGR01076 sortase_fam: sortase 94 215 7.7E-13 T 28-03-2018 IPR005754 Sortase family SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 SMART SM00382 308 502 2.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 SMART SM00382 12 210 4.3E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 Pfam PF00005 ABC transporter 300 452 8.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 Pfam PF00005 ABC transporter 4 160 2.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 504 528 0.085 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 212 244 3.1E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 SUPERFAMILY SSF52540 2 232 2.24E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 Gene3D G3DSA:3.40.50.300 269 528 1.9E-73 T 28-03-2018 SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 Gene3D G3DSA:3.40.50.300 1 267 8.0E-65 T 28-03-2018 SMD44_RS08880 16e416ab4653a236e9b21ca14a4178b2 529 SUPERFAMILY SSF52540 290 524 4.47E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19940 87a947e8e5487ccfb58c6883f471465f 357 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 345 4.1E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS19940 87a947e8e5487ccfb58c6883f471465f 357 Pfam PF00586 AIR synthase related protein, N-terminal domain 65 168 3.5E-15 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS19940 87a947e8e5487ccfb58c6883f471465f 357 SUPERFAMILY SSF56042 177 345 1.45E-51 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS19940 87a947e8e5487ccfb58c6883f471465f 357 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 341 6.9E-123 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS19940 87a947e8e5487ccfb58c6883f471465f 357 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 351 39.768 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS19940 87a947e8e5487ccfb58c6883f471465f 357 Gene3D G3DSA:3.90.650.10 175 351 1.5E-55 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS19940 87a947e8e5487ccfb58c6883f471465f 357 SUPERFAMILY SSF55326 8 173 7.92E-41 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS19940 87a947e8e5487ccfb58c6883f471465f 357 Gene3D G3DSA:3.30.1330.10 38 165 1.9E-42 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS04990 c2b87dab517d51f71d86057c7b814bd5 388 SUPERFAMILY SSF52540 203 380 2.6E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS04990 c2b87dab517d51f71d86057c7b814bd5 388 Gene3D G3DSA:3.40.50.300 5 187 1.2E-11 T 28-03-2018 SMD44_RS04990 c2b87dab517d51f71d86057c7b814bd5 388 Gene3D G3DSA:3.40.50.300 201 383 1.5E-5 T 28-03-2018 SMD44_RS04990 c2b87dab517d51f71d86057c7b814bd5 388 SUPERFAMILY SSF52540 7 177 1.73E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS35710 5bf626da708b524286822ae6bf472ecf 112 Pfam PF11774 Lsr2 1 110 5.3E-41 T 28-03-2018 IPR024412 Lsr2 SMD44_RS35710 5bf626da708b524286822ae6bf472ecf 112 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 111 5.0E-30 T 28-03-2018 IPR024412 Lsr2 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 SMART SM00354 23 93 2.0E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 Gene3D G3DSA:3.40.50.2300 194 358 3.8E-35 T 28-03-2018 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 Pfam PF00356 Bacterial regulatory proteins, lacI family 26 70 1.9E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 Gene3D G3DSA:3.40.50.2300 76 193 2.3E-21 T 28-03-2018 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 Pfam PF13377 Periplasmic binding protein-like domain 196 355 1.5E-28 T 28-03-2018 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 SUPERFAMILY SSF47413 23 81 2.13E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 Gene3D G3DSA:1.10.260.40 37 75 1.3E-22 T 28-03-2018 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 ProSitePatterns PS00356 LacI-type HTH domain signature. 26 44 - T 28-03-2018 SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 Gene3D G3DSA:1.10.10.10 7 36 0.3 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20830 25fb08cc886d607a004d262b0bf03de3 373 SUPERFAMILY SSF53822 102 359 1.16E-35 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS08475 a3514d7c7db3a7e1388ce2131bb5c6e0 320 Gene3D G3DSA:1.25.40.10 13 317 8.0E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08475 a3514d7c7db3a7e1388ce2131bb5c6e0 320 SUPERFAMILY SSF48452 83 165 2.92E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 ProSitePatterns PS00786 5'-nucleotidase signature 2. 151 162 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 32 6.8E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 Gene3D G3DSA:3.90.780.10 393 603 2.1E-45 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 SUPERFAMILY SSF56300 53 383 2.09E-74 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 PRINTS PR01607 Apyrase family signature 54 72 4.1E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 PRINTS PR01607 Apyrase family signature 447 470 4.1E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 PRINTS PR01607 Apyrase family signature 319 339 4.1E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 PRINTS PR01607 Apyrase family signature 286 309 4.1E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 PRINTS PR01607 Apyrase family signature 253 270 4.1E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 PRINTS PR01607 Apyrase family signature 538 557 4.1E-23 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 Pfam PF00149 Calcineurin-like phosphoesterase 56 303 3.0E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 SUPERFAMILY SSF55816 381 593 9.42E-42 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 Gene3D G3DSA:3.60.21.10 46 392 1.5E-75 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS10575 50f5f00306a8538e7846f9d1812dad1a 610 Pfam PF02872 5'-nucleotidase, C-terminal domain 384 563 1.3E-28 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD44_RS15485 13fad99e5cf4a2de6062949bb5334539 300 Pfam PF09126 Restriction endonuclease NaeI 3 280 4.1E-112 T 28-03-2018 IPR015210 Type-2 restriction enzyme NaeI GO:0009036|GO:0009307 SMD44_RS15485 13fad99e5cf4a2de6062949bb5334539 300 Gene3D G3DSA:3.40.600.10 1 154 3.9E-70 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 SMD44_RS15485 13fad99e5cf4a2de6062949bb5334539 300 Gene3D G3DSA:1.10.10.10 159 284 3.7E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15485 13fad99e5cf4a2de6062949bb5334539 300 SUPERFAMILY SSF52980 3 286 1.77E-78 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS42805 24f42c596c9a5939f8acab6ce131d2a4 699 Gene3D G3DSA:1.10.10.10 274 449 5.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS42805 24f42c596c9a5939f8acab6ce131d2a4 699 Gene3D G3DSA:1.25.40.10 609 682 0.38 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS42805 24f42c596c9a5939f8acab6ce131d2a4 699 SUPERFAMILY SSF52540 35 252 1.81E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS42805 24f42c596c9a5939f8acab6ce131d2a4 699 SUPERFAMILY SSF48452 472 679 5.31E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS42805 24f42c596c9a5939f8acab6ce131d2a4 699 Gene3D G3DSA:1.10.150.200 539 608 7.7E-4 T 28-03-2018 SMD44_RS42805 24f42c596c9a5939f8acab6ce131d2a4 699 Gene3D G3DSA:1.10.150.200 469 538 1.4E-5 T 28-03-2018 SMD44_RS42805 24f42c596c9a5939f8acab6ce131d2a4 699 SMART SM00382 69 207 0.0011 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS42805 24f42c596c9a5939f8acab6ce131d2a4 699 Gene3D G3DSA:3.40.50.300 37 195 4.2E-13 T 28-03-2018 SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 145 166 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 SUPERFAMILY SSF50129 1 149 2.43E-36 T 28-03-2018 IPR011032 GroES-like SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 Gene3D G3DSA:3.40.50.720 141 230 2.0E-25 T 28-03-2018 SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 SMART SM00829 10 309 5.7E-45 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 Gene3D G3DSA:3.90.180.10 231 313 4.5E-10 T 28-03-2018 SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 Gene3D G3DSA:3.90.180.10 1 140 9.8E-41 T 28-03-2018 SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 Pfam PF13602 Zinc-binding dehydrogenase 187 309 4.3E-31 T 28-03-2018 SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 SUPERFAMILY SSF51735 117 244 1.02E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS00785 2f5b9c1d4e990c16b4d86b140fe189cf 313 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 6.0E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS40485 0206e44d3c27930ec92fd93d27dde8d3 293 SUPERFAMILY SSF51055 250 292 1.7E-14 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD44_RS40485 0206e44d3c27930ec92fd93d27dde8d3 293 Gene3D G3DSA:2.60.130.10 47 236 2.2E-44 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD44_RS40485 0206e44d3c27930ec92fd93d27dde8d3 293 Pfam PF00775 Dioxygenase 87 231 5.2E-16 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMD44_RS40485 0206e44d3c27930ec92fd93d27dde8d3 293 Gene3D G3DSA:2.10.10.20 249 292 4.4E-13 T 28-03-2018 SMD44_RS40485 0206e44d3c27930ec92fd93d27dde8d3 293 SUPERFAMILY SSF49482 80 231 3.27E-45 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD44_RS40485 0206e44d3c27930ec92fd93d27dde8d3 293 SMART SM00495 247 293 4.0E-9 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 SUPERFAMILY SSF48557 27 480 1.21E-80 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 PRINTS PR00145 Argininosuccinate lyase family signature 258 282 1.1E-6 T 28-03-2018 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 PRINTS PR00145 Argininosuccinate lyase family signature 300 316 1.1E-6 T 28-03-2018 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 1.1E-6 T 28-03-2018 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 25 372 3.2E-119 T 28-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 Gene3D G3DSA:1.20.200.10 115 387 2.6E-81 T 28-03-2018 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 SMART SM00998 388 479 7.2E-5 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 ProSitePatterns PS00163 Fumarate lyases signature. 300 309 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 Gene3D G3DSA:1.10.40.30 388 479 3.8E-16 T 28-03-2018 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 Gene3D G3DSA:1.10.275.10 13 114 6.8E-15 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 Pfam PF10397 Adenylosuccinate lyase C-terminus 389 478 1.3E-8 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 PRINTS PR00149 Fumarate lyase superfamily signature 258 285 1.1E-20 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 PRINTS PR00149 Fumarate lyase superfamily signature 300 316 1.1E-20 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 1.1E-20 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 1.1E-20 T 28-03-2018 IPR000362 Fumarate lyase family SMD44_RS35175 fccc02a318648a93516c2ebf39a7e241 482 Pfam PF00206 Lyase 31 322 5.8E-30 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PIRSF PIRSF005536 1 695 1.6E-182 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 Pfam PF02065 Melibiase 266 607 5.8E-119 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 620 693 7.8E-11 T 28-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 Gene3D G3DSA:2.70.98.60 1 284 2.0E-65 T 28-03-2018 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 29 258 5.6E-51 T 28-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 215 230 1.1E-52 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 516 532 1.1E-52 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 331 346 1.1E-52 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 381 403 1.1E-52 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 267 287 1.1E-52 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 491 507 1.1E-52 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 439 454 1.1E-52 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 PRINTS PR00743 Glycosyl hydrolase family 36 signature 303 317 1.1E-52 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 SUPERFAMILY SSF51445 299 629 1.7E-100 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 Gene3D G3DSA:2.60.40.1180 605 696 1.0E-17 T 28-03-2018 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 ProSitePatterns PS00512 Alpha-galactosidase signature. 332 348 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMD44_RS35570 ba3d061e6cace83b1810b7f5763ea6d2 712 Gene3D G3DSA:3.20.20.70 286 604 1.8E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS14205 28afd7ed63281c5589254055f10e6369 411 SUPERFAMILY SSF55718 304 411 2.71E-24 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS14205 28afd7ed63281c5589254055f10e6369 411 Gene3D G3DSA:3.30.1050.10 294 403 1.6E-31 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS14205 28afd7ed63281c5589254055f10e6369 411 Pfam PF13527 Acetyltransferase (GNAT) domain 5 129 3.9E-35 T 28-03-2018 SMD44_RS14205 28afd7ed63281c5589254055f10e6369 411 Pfam PF13530 Sterol carrier protein domain 180 407 4.6E-50 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain SMD44_RS14205 28afd7ed63281c5589254055f10e6369 411 Hamap MF_01812 UPF0256 protein . 2 411 34.528 T 28-03-2018 IPR022902 N-acetyltransferase Eis SMD44_RS14205 28afd7ed63281c5589254055f10e6369 411 SUPERFAMILY SSF55729 5 303 4.25E-63 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS14205 28afd7ed63281c5589254055f10e6369 411 Gene3D G3DSA:3.40.630.30 1 97 1.1E-13 T 28-03-2018 SMD44_RS14205 28afd7ed63281c5589254055f10e6369 411 Gene3D G3DSA:3.40.630.30 122 293 4.5E-47 T 28-03-2018 SMD44_RS23615 56f509c9a960c7668e4ddfbd659ca735 79 Pfam PF04149 Domain of unknown function (DUF397) 17 69 1.9E-16 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 Gene3D G3DSA:1.25.40.70 65 144 7.9E-4 T 28-03-2018 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 Gene3D G3DSA:1.25.40.70 145 259 0.038 T 28-03-2018 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 Gene3D G3DSA:1.25.40.70 260 326 1.2E-14 T 28-03-2018 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 SUPERFAMILY SSF48371 104 325 6.72E-17 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 Pfam PF13646 HEAT repeats 108 183 7.8E-11 T 28-03-2018 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 Pfam PF13646 HEAT repeats 225 322 1.7E-10 T 28-03-2018 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 SMART SM00567 E-Z type HEAT repeats 119 148 0.13 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 SMART SM00567 E-Z type HEAT repeats 151 180 1.4 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS03530 6c3674d07ee6a16be5e172ff78266239 326 SMART SM00567 E-Z type HEAT repeats 280 309 0.025 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS39665 198582cc55362bdcb6b4d0c6a1e0782a 369 Gene3D G3DSA:3.90.1150.10 239 369 7.2E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS39665 198582cc55362bdcb6b4d0c6a1e0782a 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 363 7.2E-111 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD44_RS39665 198582cc55362bdcb6b4d0c6a1e0782a 369 Gene3D G3DSA:3.40.640.10 16 238 1.5E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS39665 198582cc55362bdcb6b4d0c6a1e0782a 369 PIRSF PIRSF000390 3 368 1.6E-97 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD44_RS39665 198582cc55362bdcb6b4d0c6a1e0782a 369 SUPERFAMILY SSF53383 17 366 3.94E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS20145 23ef84a6ae3514f2b02edf57abb1c60b 311 SUPERFAMILY SSF53850 88 295 3.1E-26 T 28-03-2018 SMD44_RS20145 23ef84a6ae3514f2b02edf57abb1c60b 311 Pfam PF03466 LysR substrate binding domain 87 292 2.3E-28 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS20145 23ef84a6ae3514f2b02edf57abb1c60b 311 Gene3D G3DSA:3.40.190.10 177 266 1.6E-13 T 28-03-2018 SMD44_RS20145 23ef84a6ae3514f2b02edf57abb1c60b 311 Gene3D G3DSA:3.40.190.10 89 176 2.4E-17 T 28-03-2018 SMD44_RS20145 23ef84a6ae3514f2b02edf57abb1c60b 311 SUPERFAMILY SSF46785 1 85 3.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20145 23ef84a6ae3514f2b02edf57abb1c60b 311 Gene3D G3DSA:1.10.10.10 1 88 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20145 23ef84a6ae3514f2b02edf57abb1c60b 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.6E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 SUPERFAMILY SSF52540 1 214 1.09E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 Gene3D G3DSA:3.40.50.300 1 217 1.1E-63 T 28-03-2018 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 Pfam PF00406 Adenylate kinase 5 191 1.3E-60 T 28-03-2018 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 1.4E-78 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 PRINTS PR00094 Adenylate kinase signature 32 46 1.9E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 PRINTS PR00094 Adenylate kinase signature 161 176 1.9E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 PRINTS PR00094 Adenylate kinase signature 178 192 1.9E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 PRINTS PR00094 Adenylate kinase signature 81 97 1.9E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 PRINTS PR00094 Adenylate kinase signature 4 17 1.9E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 Pfam PF05191 Adenylate kinase, active site lid 127 163 1.2E-12 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 SMD44_RS25610 fead3ddcabce6541daf2fa8f8a0d31da 217 Hamap MF_00235 Adenylate kinase [adk]. 1 214 51.844 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD44_RS16515 f7bb157d9315406e46c5405ca99804ce 137 SUPERFAMILY SSF54593 5 129 2.61E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS16515 f7bb157d9315406e46c5405ca99804ce 137 Gene3D G3DSA:3.10.180.10 1 130 2.3E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS14285 eae3f9d529b6e011e05fcc7760b5359c 148 Pfam PF00293 NUDIX domain 6 123 1.3E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS14285 eae3f9d529b6e011e05fcc7760b5359c 148 PRINTS PR00502 NUDIX hydrolase family signature 47 62 4.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS14285 eae3f9d529b6e011e05fcc7760b5359c 148 PRINTS PR00502 NUDIX hydrolase family signature 33 47 4.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS14285 eae3f9d529b6e011e05fcc7760b5359c 148 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS14285 eae3f9d529b6e011e05fcc7760b5359c 148 SUPERFAMILY SSF55811 5 138 9.61E-27 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS14285 eae3f9d529b6e011e05fcc7760b5359c 148 Gene3D G3DSA:3.90.79.10 3 129 2.7E-25 T 28-03-2018 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 Pfam PF13245 AAA domain 69 313 6.1E-37 T 28-03-2018 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 Pfam PF13361 UvrD-like helicase C-terminal domain 498 607 1.7E-22 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 Pfam PF13361 UvrD-like helicase C-terminal domain 335 456 1.6E-15 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 Gene3D G3DSA:3.40.50.300 57 331 8.8E-49 T 28-03-2018 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 Gene3D G3DSA:1.10.150.80 687 779 5.6E-20 T 28-03-2018 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 SUPERFAMILY SSF52540 60 627 1.26E-118 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 SUPERFAMILY SSF47819 690 770 6.98E-19 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 SMART SM00341 697 777 4.0E-19 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 Pfam PF00570 HRDC domain 701 766 1.2E-20 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD44_RS28095 728261a4f59ba836601d082dab250f61 779 Gene3D G3DSA:3.40.50.300 332 631 7.1E-52 T 28-03-2018 SMD44_RS36765 5439d00e3c66888c01ef33c7a9ebbbcd 265 PIRSF PIRSF006648 1 264 2.5E-25 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS36765 5439d00e3c66888c01ef33c7a9ebbbcd 265 Pfam PF01061 ABC-2 type transporter 17 227 4.8E-19 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS21830 c6bbacc34ecb7dd863d4fc72cf9020a6 301 SUPERFAMILY SSF56601 23 299 3.15E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS21830 c6bbacc34ecb7dd863d4fc72cf9020a6 301 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 126 143 1.0E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS21830 c6bbacc34ecb7dd863d4fc72cf9020a6 301 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 159 172 1.0E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS21830 c6bbacc34ecb7dd863d4fc72cf9020a6 301 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 1.0E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS21830 c6bbacc34ecb7dd863d4fc72cf9020a6 301 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 41 279 3.0E-43 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD44_RS21830 c6bbacc34ecb7dd863d4fc72cf9020a6 301 Gene3D G3DSA:3.40.710.10 11 301 1.5E-51 T 28-03-2018 SMD44_RS16025 f0b90d0c8d3700fb8ebd50c01b9d1337 471 Gene3D G3DSA:1.20.1250.20 66 266 6.1E-9 T 28-03-2018 SMD44_RS16025 f0b90d0c8d3700fb8ebd50c01b9d1337 471 SUPERFAMILY SSF103473 58 452 1.14E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS16025 f0b90d0c8d3700fb8ebd50c01b9d1337 471 Gene3D G3DSA:1.20.1250.20 268 467 6.0E-14 T 28-03-2018 SMD44_RS16025 f0b90d0c8d3700fb8ebd50c01b9d1337 471 Pfam PF07690 Major Facilitator Superfamily 79 358 8.8E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS30085 ed9c6f76518193921d1c01f3ccf40387 429 SUPERFAMILY SSF82171 51 410 2.62E-28 T 28-03-2018 SMD44_RS30085 ed9c6f76518193921d1c01f3ccf40387 429 Pfam PF07676 WD40-like Beta Propeller Repeat 50 86 0.0082 T 28-03-2018 IPR011659 WD40-like Beta Propeller SMD44_RS30085 ed9c6f76518193921d1c01f3ccf40387 429 Pfam PF07676 WD40-like Beta Propeller Repeat 277 307 0.092 T 28-03-2018 IPR011659 WD40-like Beta Propeller SMD44_RS30085 ed9c6f76518193921d1c01f3ccf40387 429 Gene3D G3DSA:2.130.10.10 34 148 4.1E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS30085 ed9c6f76518193921d1c01f3ccf40387 429 Gene3D G3DSA:2.130.10.10 254 423 4.4E-15 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS30085 ed9c6f76518193921d1c01f3ccf40387 429 Gene3D G3DSA:2.130.10.10 149 253 2.7E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 Pfam PF00561 alpha/beta hydrolase fold 32 146 8.8E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 Pfam PF00106 short chain dehydrogenase 327 517 8.6E-56 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 Gene3D G3DSA:3.40.50.1820 9 299 8.6E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 Gene3D G3DSA:3.40.50.720 300 591 5.4E-64 T 28-03-2018 SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 SUPERFAMILY SSF51735 322 587 2.91E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 476 495 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 456 464 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 402 413 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 SUPERFAMILY SSF53474 8 299 7.47E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 463 491 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 476 495 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 327 344 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 402 413 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 497 514 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 450 466 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20770 8c6f8bb51256b9e3f7bde24a344e60f5 593 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 326 507 0.0035 T 28-03-2018 SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 SUPERFAMILY SSF56784 23 208 2.44E-44 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 138 201 3.2E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 Gene3D G3DSA:3.40.50.1000 21 216 4.2E-35 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 1.3E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 23 34 1.3E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 1.3E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 191 204 1.3E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 128 1.3E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS42725 ac0b66ec068e5561e1cbb711c259e5f2 256 Pfam PF13419 Haloacid dehalogenase-like hydrolase 26 202 1.0E-26 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 Pfam PF01494 FAD binding domain 16 356 5.2E-83 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 SUPERFAMILY SSF51905 16 195 7.78E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 SUPERFAMILY SSF51905 278 365 7.78E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 3.7E-39 T 28-03-2018 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 342 358 3.7E-39 T 28-03-2018 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 18 40 3.7E-39 T 28-03-2018 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 3.7E-39 T 28-03-2018 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 342 3.7E-39 T 28-03-2018 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 3.7E-39 T 28-03-2018 SMD44_RS29505 f56e563b47f7ae99f3cde029a5594507 536 Gene3D G3DSA:3.50.50.60 14 393 5.6E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS31575 08eaf91464b99d2d66c8efd052df8bf4 225 PIRSF PIRSF006171 1 224 2.0E-79 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMD44_RS31575 08eaf91464b99d2d66c8efd052df8bf4 225 Gene3D G3DSA:1.10.10.10 134 224 3.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31575 08eaf91464b99d2d66c8efd052df8bf4 225 Gene3D G3DSA:3.40.50.2300 1 133 2.4E-30 T 28-03-2018 SMD44_RS31575 08eaf91464b99d2d66c8efd052df8bf4 225 SUPERFAMILY SSF52172 1 126 5.41E-33 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS31575 08eaf91464b99d2d66c8efd052df8bf4 225 Pfam PF08279 HTH domain 165 201 6.2E-9 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SMD44_RS31575 08eaf91464b99d2d66c8efd052df8bf4 225 Pfam PF00072 Response regulator receiver domain 4 115 1.4E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31575 08eaf91464b99d2d66c8efd052df8bf4 225 SUPERFAMILY SSF46785 168 222 4.25E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31575 08eaf91464b99d2d66c8efd052df8bf4 225 SMART SM00448 2 115 3.6E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 34 264 4.1E-48 T 28-03-2018 SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 SUPERFAMILY SSF51735 21 265 1.33E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 9.5E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 9.5E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 9.5E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 9.5E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 9.5E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 9.5E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS36655 cdc512d38c8d85aab88341e86057c0ee 266 Gene3D G3DSA:3.40.50.720 24 266 9.8E-64 T 28-03-2018 SMD44_RS23260 89539f85e514495362fc08af752bff6b 370 SUPERFAMILY SSF52540 133 358 8.25E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23260 89539f85e514495362fc08af752bff6b 370 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 137 336 7.2E-7 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMD44_RS23260 89539f85e514495362fc08af752bff6b 370 Gene3D G3DSA:3.40.50.300 131 365 3.3E-27 T 28-03-2018 SMD44_RS23260 89539f85e514495362fc08af752bff6b 370 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 23 362 8.8E-101 T 28-03-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like SMD44_RS07055 9c5df060267935bcaea600f690916b7c 435 SUPERFAMILY SSF48230 99 379 5.13E-61 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMD44_RS07055 9c5df060267935bcaea600f690916b7c 435 Pfam PF05426 Alginate lyase 94 378 5.9E-91 T 28-03-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 SMD44_RS07055 9c5df060267935bcaea600f690916b7c 435 Gene3D G3DSA:1.50.10.100 106 407 1.6E-56 T 28-03-2018 SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 231 364 5.2E-29 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 SUPERFAMILY SSF52467 197 376 2.5E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 16 632 5.1E-268 T 28-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 18 210 7.6E-33 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 Gene3D G3DSA:3.40.50.970 398 617 3.7E-43 T 28-03-2018 SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 SUPERFAMILY SSF52518 406 623 1.0E-51 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 Gene3D G3DSA:3.40.50.970 11 227 9.6E-48 T 28-03-2018 SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 Gene3D G3DSA:3.40.50.1220 228 397 1.5E-39 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 428 586 5.9E-43 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD44_RS14715 55d52603631f8b86cf01c28679082591 635 SUPERFAMILY SSF52518 13 220 6.99E-32 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 SUPERFAMILY SSF55874 170 352 1.06E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 SUPERFAMILY SSF47384 100 180 5.89E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 SMART SM00387 239 354 1.6E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 Gene3D G3DSA:3.30.450.20 61 120 0.0029 T 28-03-2018 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 Pfam PF00512 His Kinase A (phospho-acceptor) domain 117 180 7.6E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 292 8.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 333 8.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 351 8.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 306 8.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 SMART SM00304 62 115 1.1E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 Pfam PF00672 HAMP domain 62 111 1.7E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 240 351 1.9E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 Gene3D G3DSA:1.10.287.130 121 174 3.1E-17 T 28-03-2018 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 SUPERFAMILY SSF158472 63 111 5.36E-10 T 28-03-2018 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 SMART SM00388 116 180 1.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS28595 16f9def5e6e98ccd0590aba346baa748 356 Gene3D G3DSA:3.30.565.10 175 352 1.8E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17545 a486742faf509b313a4d771464a432ba 188 Pfam PF05685 Putative restriction endonuclease 18 144 4.0E-19 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS17545 a486742faf509b313a4d771464a432ba 188 SUPERFAMILY SSF52980 12 147 9.65E-19 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS17545 a486742faf509b313a4d771464a432ba 188 Gene3D G3DSA:3.90.1570.10 9 188 5.5E-28 T 28-03-2018 SMD44_RS41130 9b793aff083ae6dc4ef42b133d68ee12 61 Gene3D G3DSA:1.10.1220.10 1 55 2.6E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS42015 824790abe952ae9c978fab4b7b814ba2 222 SUPERFAMILY SSF52172 1 168 8.42E-31 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS42015 824790abe952ae9c978fab4b7b814ba2 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 215 2.2E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS42015 824790abe952ae9c978fab4b7b814ba2 222 Gene3D G3DSA:3.40.50.2300 1 122 3.0E-25 T 28-03-2018 SMD44_RS42015 824790abe952ae9c978fab4b7b814ba2 222 Gene3D G3DSA:1.10.10.10 123 221 1.6E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS42015 824790abe952ae9c978fab4b7b814ba2 222 Pfam PF00072 Response regulator receiver domain 1 111 4.7E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS42015 824790abe952ae9c978fab4b7b814ba2 222 SMART SM00448 1 110 2.4E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS42015 824790abe952ae9c978fab4b7b814ba2 222 SMART SM00862 143 215 1.7E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS13020 7ee1fc41f2a34f5a7706e370b858c190 283 Gene3D G3DSA:3.40.190.10 62 152 2.8E-15 T 28-03-2018 SMD44_RS13020 7ee1fc41f2a34f5a7706e370b858c190 283 Gene3D G3DSA:3.40.190.10 242 282 0.0024 T 28-03-2018 SMD44_RS13020 7ee1fc41f2a34f5a7706e370b858c190 283 PIRSF PIRSF004846 20 283 9.4E-65 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 SMD44_RS13020 7ee1fc41f2a34f5a7706e370b858c190 283 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 71 277 8.2E-42 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 SMD44_RS13020 7ee1fc41f2a34f5a7706e370b858c190 283 Gene3D G3DSA:3.40.190.10 153 241 3.6E-27 T 28-03-2018 SMD44_RS13020 7ee1fc41f2a34f5a7706e370b858c190 283 Pfam PF13531 Bacterial extracellular solute-binding protein 66 281 4.8E-48 T 28-03-2018 SMD44_RS13020 7ee1fc41f2a34f5a7706e370b858c190 283 SUPERFAMILY SSF53850 65 282 5.56E-54 T 28-03-2018 SMD44_RS26190 a9318cd7c42fb03e34cab2de3d6f8c34 176 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 40 88 1.8E-19 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS26190 a9318cd7c42fb03e34cab2de3d6f8c34 176 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 105 2.3E-18 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS26190 a9318cd7c42fb03e34cab2de3d6f8c34 176 Gene3D G3DSA:1.20.1290.10 14 163 3.4E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS26190 a9318cd7c42fb03e34cab2de3d6f8c34 176 SUPERFAMILY SSF69118 16 157 5.98E-41 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS36760 e5ac582882b943d71659eb4ed10eacf8 542 SUPERFAMILY SSF54373 340 455 2.42E-25 T 28-03-2018 SMD44_RS36760 e5ac582882b943d71659eb4ed10eacf8 542 Gene3D G3DSA:3.50.50.60 422 541 3.2E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36760 e5ac582882b943d71659eb4ed10eacf8 542 Gene3D G3DSA:3.90.660.10 68 421 6.8E-44 T 28-03-2018 SMD44_RS36760 e5ac582882b943d71659eb4ed10eacf8 542 Pfam PF01593 Flavin containing amine oxidoreductase 39 509 8.0E-45 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS36760 e5ac582882b943d71659eb4ed10eacf8 542 SUPERFAMILY SSF51905 477 518 1.47E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36760 e5ac582882b943d71659eb4ed10eacf8 542 SUPERFAMILY SSF51905 30 361 1.47E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36760 e5ac582882b943d71659eb4ed10eacf8 542 Gene3D G3DSA:3.40.50.720 22 67 1.5E-6 T 28-03-2018 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 SUPERFAMILY SSF51735 2 140 5.81E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 Gene3D G3DSA:3.40.50.720 1 133 1.5E-21 T 28-03-2018 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 Pfam PF02254 TrkA-N domain 3 116 2.2E-25 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.4E-9 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 4.4E-9 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 4.4E-9 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.4E-9 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 Gene3D G3DSA:3.30.70.1450 146 218 2.1E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 Pfam PF02080 TrkA-C domain 149 213 4.0E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS31915 90251b1347c00e5258f108b01aea3411 222 SUPERFAMILY SSF116726 143 211 7.72E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS31215 e2b729e90229840790246862da1222b0 265 Gene3D G3DSA:1.10.10.10 1 91 7.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31215 e2b729e90229840790246862da1222b0 265 SUPERFAMILY SSF46785 2 98 1.93E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31215 e2b729e90229840790246862da1222b0 265 SMART SM00418 3 78 1.4E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS31215 e2b729e90229840790246862da1222b0 265 Pfam PF12840 Helix-turn-helix domain 2 62 1.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31215 e2b729e90229840790246862da1222b0 265 SUPERFAMILY SSF55961 102 259 9.73E-32 T 28-03-2018 SMD44_RS31215 e2b729e90229840790246862da1222b0 265 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 117 254 1.6E-22 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMD44_RS31215 e2b729e90229840790246862da1222b0 265 Gene3D G3DSA:3.30.530.20 104 256 1.4E-30 T 28-03-2018 IPR023393 START-like domain SMD44_RS31215 e2b729e90229840790246862da1222b0 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 9.3E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS31215 e2b729e90229840790246862da1222b0 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 9.3E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS31215 e2b729e90229840790246862da1222b0 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 9.3E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS13600 3bbc0f51da522113027adb6d049ed8c2 315 PIRSF PIRSF001439 1 314 2.3E-47 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMD44_RS13600 3bbc0f51da522113027adb6d049ed8c2 315 Gene3D G3DSA:3.30.1780.10 1 135 7.8E-29 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMD44_RS13600 3bbc0f51da522113027adb6d049ed8c2 315 SUPERFAMILY SSF51735 1 313 1.38E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS13600 3bbc0f51da522113027adb6d049ed8c2 315 Gene3D G3DSA:3.40.50.720 136 286 1.7E-24 T 28-03-2018 SMD44_RS13600 3bbc0f51da522113027adb6d049ed8c2 315 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 5 304 1.5E-42 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMD44_RS39415 e9fb3fff1a7c90df3691fd2a7ce728ac 264 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 257 5.3E-34 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 Pfam PF00072 Response regulator receiver domain 10 123 6.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 SMART SM00421 155 212 9.7E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 SUPERFAMILY SSF46894 147 218 8.84E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 Gene3D G3DSA:3.40.50.2300 7 140 2.8E-35 T 28-03-2018 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 2.0E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 6.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 6.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 6.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 Gene3D G3DSA:1.10.10.10 141 217 1.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 SMART SM00448 8 122 7.8E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS09770 68469009ff1e31fd4a0c3e7ef8793819 221 SUPERFAMILY SSF52172 7 128 1.85E-31 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS18160 cbe2f9bcec47239cbccf6326e28265c8 228 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 33 206 2.3E-23 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS18160 cbe2f9bcec47239cbccf6326e28265c8 228 SMART SM00943 33 214 2.0E-37 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS35575 04a665abc6854db902e6483a7592b42b 259 SUPERFAMILY SSF52266 11 197 1.53E-35 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS35575 04a665abc6854db902e6483a7592b42b 259 Gene3D G3DSA:3.40.50.1110 1 208 5.3E-33 T 28-03-2018 SMD44_RS35575 04a665abc6854db902e6483a7592b42b 259 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 14 187 9.1E-27 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 Pfam PF03129 Anticodon binding domain 475 562 2.1E-15 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 6 558 5.8E-171 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 Hamap MF_01569 Proline--tRNA ligase [proS]. 5 564 35.855 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 SUPERFAMILY SSF55826 252 411 2.62E-22 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 Gene3D G3DSA:3.40.50.800 458 564 1.4E-25 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 Gene3D G3DSA:3.90.960.10 244 388 8.2E-39 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 1.9E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 72 90 1.9E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 108 119 1.9E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 148 159 1.9E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 SUPERFAMILY SSF55681 14 241 2.39E-87 T 28-03-2018 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 SUPERFAMILY SSF55681 406 477 2.39E-87 T 28-03-2018 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 Pfam PF04073 Aminoacyl-tRNA editing domain 260 374 8.7E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 Gene3D G3DSA:3.30.930.10 17 221 2.1E-51 T 28-03-2018 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 Gene3D G3DSA:3.30.930.10 392 457 3.5E-9 T 28-03-2018 SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 SUPERFAMILY SSF52954 460 563 4.09E-22 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS30825 cb6a857f46d34b61bea88f7290c7a1b6 564 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 98 457 2.0E-42 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS18515 cb7710eba1257863a3e3ec6d68b76855 182 Gene3D G3DSA:3.40.630.30 7 167 1.5E-23 T 28-03-2018 SMD44_RS18515 cb7710eba1257863a3e3ec6d68b76855 182 Pfam PF13673 Acetyltransferase (GNAT) domain 72 172 1.7E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS18515 cb7710eba1257863a3e3ec6d68b76855 182 SUPERFAMILY SSF55729 17 179 1.62E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS11675 88550cf312129ef219405200a27fa795 334 Pfam PF01758 Sodium Bile acid symporter family 47 220 5.9E-13 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 Hamap MF_01113 DNA polymerase IV [dinB]. 4 352 34.445 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 SUPERFAMILY SSF56672 6 239 2.49E-69 T 28-03-2018 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 Pfam PF00817 impB/mucB/samB family 10 158 1.1E-43 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 Pfam PF11799 impB/mucB/samB family C-terminal domain 239 346 1.4E-20 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 Gene3D G3DSA:3.30.1490.100 249 352 3.2E-26 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 SUPERFAMILY SSF100879 243 343 2.04E-24 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 Gene3D G3DSA:3.30.70.270 43 118 2.0E-21 T 28-03-2018 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 Gene3D G3DSA:3.30.70.270 119 174 2.7E-12 T 28-03-2018 SMD44_RS06600 b4e3e361dd6e9f5b3edb48341c61a9ce 544 Gene3D G3DSA:1.10.150.20 175 248 3.0E-18 T 28-03-2018 SMD44_RS18085 200e2dc511582ceac22444dcfe35132d 156 Gene3D G3DSA:3.30.565.10 1 140 5.4E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18085 200e2dc511582ceac22444dcfe35132d 156 Pfam PF13581 Histidine kinase-like ATPase domain 13 123 1.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18085 200e2dc511582ceac22444dcfe35132d 156 SUPERFAMILY SSF55874 38 123 9.3E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 Gene3D G3DSA:3.40.190.10 186 278 8.1E-24 T 28-03-2018 SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 SUPERFAMILY SSF46785 7 119 5.63E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 SUPERFAMILY SSF53850 99 309 2.17E-37 T 28-03-2018 SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 Pfam PF03466 LysR substrate binding domain 97 304 4.9E-42 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 71 4.2E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 Gene3D G3DSA:3.40.190.10 97 185 2.9E-21 T 28-03-2018 SMD44_RS27450 6fc52c7360c424c5b989a4aa95f591c0 312 Gene3D G3DSA:1.10.10.10 6 92 1.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19350 3b56ab3106c16b62a8a15b12e37a847c 303 Pfam PF00005 ABC transporter 24 159 5.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19350 3b56ab3106c16b62a8a15b12e37a847c 303 SMART SM00382 32 207 6.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19350 3b56ab3106c16b62a8a15b12e37a847c 303 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS19350 3b56ab3106c16b62a8a15b12e37a847c 303 Gene3D G3DSA:3.40.50.300 2 249 5.7E-55 T 28-03-2018 SMD44_RS19350 3b56ab3106c16b62a8a15b12e37a847c 303 SUPERFAMILY SSF52540 5 222 1.21E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18315 85747e390941cee29657230d0059cc45 400 SUPERFAMILY SSF47413 9 69 5.63E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS18315 85747e390941cee29657230d0059cc45 400 Gene3D G3DSA:1.10.260.40 5 63 4.0E-9 T 28-03-2018 SMD44_RS18315 85747e390941cee29657230d0059cc45 400 SMART SM00530 12 66 6.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS18315 85747e390941cee29657230d0059cc45 400 Pfam PF13560 Helix-turn-helix domain 10 64 9.4E-7 T 28-03-2018 SMD44_RS18315 85747e390941cee29657230d0059cc45 400 Gene3D G3DSA:1.25.40.10 64 289 3.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS18285 5ccfc80a8db7d179c29e6044248bbffc 281 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 20 270 3.4E-111 T 28-03-2018 IPR017518 Conserved hypothetical protein CHP03084 SMD44_RS18285 5ccfc80a8db7d179c29e6044248bbffc 281 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 24 160 1.6E-30 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS18285 5ccfc80a8db7d179c29e6044248bbffc 281 Gene3D G3DSA:1.20.120.450 10 166 4.5E-25 T 28-03-2018 SMD44_RS18285 5ccfc80a8db7d179c29e6044248bbffc 281 SUPERFAMILY SSF109854 16 165 2.29E-34 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS18285 5ccfc80a8db7d179c29e6044248bbffc 281 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 23 237 8.4E-50 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS18285 5ccfc80a8db7d179c29e6044248bbffc 281 Pfam PF08608 Wyosine base formation 196 246 4.7E-7 T 28-03-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD44_RS07010 4ae53d91024f12a7d301f416e4422074 168 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 151 2.1E-42 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07010 4ae53d91024f12a7d301f416e4422074 168 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 156 28.412 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07010 4ae53d91024f12a7d301f416e4422074 168 Gene3D G3DSA:3.40.50.960 2 158 4.6E-58 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07010 4ae53d91024f12a7d301f416e4422074 168 SUPERFAMILY SSF52121 11 156 9.29E-55 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07010 4ae53d91024f12a7d301f416e4422074 168 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 152 1.8E-51 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS23900 566668c21d139a5d4a4ccbd02d320588 226 Gene3D G3DSA:2.70.70.10 46 222 9.7E-45 T 28-03-2018 SMD44_RS23900 566668c21d139a5d4a4ccbd02d320588 226 SUPERFAMILY SSF51261 60 219 4.76E-44 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS23900 566668c21d139a5d4a4ccbd02d320588 226 Pfam PF01551 Peptidase family M23 113 215 2.1E-30 T 28-03-2018 IPR016047 Peptidase M23 SMD44_RS15180 e167e14bab3c02201f4f0a6b93716f62 336 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 128 295 1.3E-46 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD44_RS15180 e167e14bab3c02201f4f0a6b93716f62 336 Gene3D G3DSA:3.40.50.720 133 298 1.9E-47 T 28-03-2018 SMD44_RS15180 e167e14bab3c02201f4f0a6b93716f62 336 Gene3D G3DSA:3.40.50.720 21 132 9.6E-20 T 28-03-2018 SMD44_RS15180 e167e14bab3c02201f4f0a6b93716f62 336 SUPERFAMILY SSF52283 51 149 2.26E-11 T 28-03-2018 SMD44_RS15180 e167e14bab3c02201f4f0a6b93716f62 336 SUPERFAMILY SSF51735 121 294 3.19E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS13780 aa77e1ed2c61e18c436108fc7b3306c8 133 Gene3D G3DSA:3.10.180.10 1 132 1.2E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS13780 aa77e1ed2c61e18c436108fc7b3306c8 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 122 1.2E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS13780 aa77e1ed2c61e18c436108fc7b3306c8 133 SUPERFAMILY SSF54593 3 126 5.23E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS33570 709407dce06cf637b42bf9b99eb3e264 405 SUPERFAMILY SSF55874 285 403 2.32E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS33570 709407dce06cf637b42bf9b99eb3e264 405 Pfam PF07730 Histidine kinase 204 267 3.5E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS33570 709407dce06cf637b42bf9b99eb3e264 405 Gene3D G3DSA:3.30.565.10 276 405 2.2E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 Gene3D G3DSA:1.10.1740.10 12 103 7.2E-17 T 28-03-2018 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 Pfam PF04542 Sigma-70 region 2 27 98 2.0E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 186 2.1E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 PRINTS PR00046 Major sigma-70 factor signature 142 154 7.4E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 PRINTS PR00046 Major sigma-70 factor signature 56 69 7.4E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 PRINTS PR00046 Major sigma-70 factor signature 159 174 7.4E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 PRINTS PR00046 Major sigma-70 factor signature 174 185 7.4E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 Gene3D G3DSA:1.10.10.10 111 191 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 Pfam PF04545 Sigma-70, region 4 138 187 4.5E-12 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 SUPERFAMILY SSF88946 11 112 8.04E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS25810 4ff9a436cc6a832c4661cd3db83f25ff 191 SUPERFAMILY SSF88659 116 189 1.64E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13455 82ae1f7608cbfb0a9e0a9296cbaca440 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 286 9.9E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13455 82ae1f7608cbfb0a9e0a9296cbaca440 300 SUPERFAMILY SSF161098 53 287 5.76E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13455 82ae1f7608cbfb0a9e0a9296cbaca440 300 Gene3D G3DSA:1.10.3720.10 10 293 2.7E-42 T 28-03-2018 SMD44_RS38975 d1d1f4159578dadd4e34113191b0fc0f 369 Gene3D G3DSA:2.130.10.10 41 201 1.6E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS38975 d1d1f4159578dadd4e34113191b0fc0f 369 Gene3D G3DSA:2.130.10.10 202 361 7.5E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS38975 d1d1f4159578dadd4e34113191b0fc0f 369 SUPERFAMILY SSF82171 62 322 1.57E-19 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 Gene3D G3DSA:3.40.50.1000 575 715 1.1E-38 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 210 753 3.9E-153 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 Pfam PF00403 Heavy-metal-associated domain 14 73 2.3E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 Pfam PF00702 haloacid dehalogenase-like hydrolase 444 664 4.9E-45 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 Gene3D G3DSA:3.30.70.100 8 77 1.9E-20 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 ProSitePatterns PS01047 Heavy-metal-associated domain. 16 44 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 Pfam PF00122 E1-E2 ATPase 251 426 3.6E-56 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 SUPERFAMILY SSF81665 199 252 8.63E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 SUPERFAMILY SSF81665 349 442 8.63E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 SUPERFAMILY SSF81665 699 727 8.63E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 SUPERFAMILY SSF55008 8 75 1.11E-19 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 298 312 4.4E-23 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 673 685 4.4E-23 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 595 605 4.4E-23 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 448 462 4.4E-23 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 650 669 4.4E-23 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 Gene3D G3DSA:1.20.1110.10 210 463 1.6E-47 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 167 752 2.4E-179 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 Gene3D G3DSA:3.40.1110.10 464 574 6.0E-31 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 SUPERFAMILY SSF56784 505 750 3.81E-53 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 SUPERFAMILY SSF56784 446 466 3.81E-53 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00943 Copper-transporting ATPase signature 431 446 2.2E-8 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00943 Copper-transporting ATPase signature 26 40 2.2E-8 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00943 Copper-transporting ATPase signature 218 237 2.2E-8 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00943 Copper-transporting ATPase signature 684 698 2.2E-8 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00943 Copper-transporting ATPase signature 371 385 2.2E-8 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 PRINTS PR00943 Copper-transporting ATPase signature 627 644 2.2E-8 T 28-03-2018 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 450 456 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 SUPERFAMILY SSF81653 254 348 8.37E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMD44_RS18680 58ef12901c375bec8d26b5972379a981 759 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 222 731 2.4E-84 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS20325 b6b6dfd0413cd200db4f6063e2aff265 311 Gene3D G3DSA:3.20.20.140 43 310 1.2E-43 T 28-03-2018 SMD44_RS20325 b6b6dfd0413cd200db4f6063e2aff265 311 Pfam PF04909 Amidohydrolase 38 310 1.7E-39 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS20325 b6b6dfd0413cd200db4f6063e2aff265 311 Gene3D G3DSA:2.30.40.10 5 42 0.0014 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS20325 b6b6dfd0413cd200db4f6063e2aff265 311 SUPERFAMILY SSF51556 38 310 2.16E-52 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS08040 e7db62b84ea7601e7f30314bc2593b79 199 Pfam PF13302 Acetyltransferase (GNAT) domain 28 165 1.1E-25 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS08040 e7db62b84ea7601e7f30314bc2593b79 199 Gene3D G3DSA:3.40.630.30 26 193 1.1E-27 T 28-03-2018 SMD44_RS08040 e7db62b84ea7601e7f30314bc2593b79 199 SUPERFAMILY SSF55729 27 190 3.29E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS01515 3b5cc81575928de1637dcae3e8edecfd 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 296 1.6E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS01515 3b5cc81575928de1637dcae3e8edecfd 305 Gene3D G3DSA:1.20.58.370 3 39 1.2E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMD44_RS01515 3b5cc81575928de1637dcae3e8edecfd 305 SUPERFAMILY SSF161098 20 302 1.78E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS01515 3b5cc81575928de1637dcae3e8edecfd 305 Gene3D G3DSA:1.10.3720.10 40 302 2.8E-42 T 28-03-2018 SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 1.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 1.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 1.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 1.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 Gene3D G3DSA:1.10.10.10 16 147 1.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 SUPERFAMILY SSF46785 5 147 5.37E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 75 109 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 Pfam PF12802 MarR family 42 99 3.1E-16 T 28-03-2018 SMD44_RS12835 a2d5881a3089ec56dc93bd93c1e1e129 148 SMART SM00347 37 135 1.3E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS27705 18bb446f59edc0f7ef48d7c308c608d4 382 Pfam PF00005 ABC transporter 74 225 5.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS27705 18bb446f59edc0f7ef48d7c308c608d4 382 SMART SM00382 82 275 1.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS27705 18bb446f59edc0f7ef48d7c308c608d4 382 SUPERFAMILY SSF52540 45 297 1.98E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27705 18bb446f59edc0f7ef48d7c308c608d4 382 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 276 353 8.3E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS27705 18bb446f59edc0f7ef48d7c308c608d4 382 ProSitePatterns PS00211 ABC transporters family signature. 198 212 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS27705 18bb446f59edc0f7ef48d7c308c608d4 382 Gene3D G3DSA:3.40.50.300 42 381 7.0E-85 T 28-03-2018 SMD44_RS27705 18bb446f59edc0f7ef48d7c308c608d4 382 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 278 344 1.7E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS16390 6e018ab454e46a2b45d0e7845673cd3d 449 SUPERFAMILY SSF53697 97 165 1.29E-9 T 28-03-2018 SMD44_RS16390 6e018ab454e46a2b45d0e7845673cd3d 449 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 292 446 2.1E-22 T 28-03-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 SMD44_RS16390 6e018ab454e46a2b45d0e7845673cd3d 449 SUPERFAMILY SSF53697 222 446 2.45E-33 T 28-03-2018 SMD44_RS16390 6e018ab454e46a2b45d0e7845673cd3d 449 Gene3D G3DSA:3.40.50.10490 284 446 2.2E-39 T 28-03-2018 SMD44_RS16390 6e018ab454e46a2b45d0e7845673cd3d 449 Gene3D G3DSA:3.40.50.10490 7 190 9.0E-10 T 28-03-2018 SMD44_RS02965 3c28a25ea53c9c783f3d9b75f95c7ae2 375 Gene3D G3DSA:2.130.10.10 14 162 2.2E-14 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS02965 3c28a25ea53c9c783f3d9b75f95c7ae2 375 Gene3D G3DSA:2.130.10.10 163 308 1.2E-26 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS02965 3c28a25ea53c9c783f3d9b75f95c7ae2 375 Gene3D G3DSA:2.130.10.10 309 372 6.7E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS02965 3c28a25ea53c9c783f3d9b75f95c7ae2 375 Pfam PF10282 Lactonase, 7-bladed beta-propeller 34 372 5.0E-105 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller SMD44_RS02965 3c28a25ea53c9c783f3d9b75f95c7ae2 375 SUPERFAMILY SSF51004 53 356 2.62E-51 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain SMD44_RS15560 dc89651c34246242c75a2dfe31f4ebda 333 SUPERFAMILY SSF52540 41 256 2.51E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15560 dc89651c34246242c75a2dfe31f4ebda 333 SMART SM00382 55 240 1.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS15560 dc89651c34246242c75a2dfe31f4ebda 333 Gene3D G3DSA:3.40.50.300 15 296 1.2E-53 T 28-03-2018 SMD44_RS15560 dc89651c34246242c75a2dfe31f4ebda 333 Pfam PF00005 ABC transporter 47 190 1.7E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS16800 ae0e93d2474b26a764b900c21233f479 364 Pfam PF06737 Transglycosylase-like domain 40 115 8.5E-31 T 28-03-2018 IPR010618 Transglycosylase-like SMD44_RS16800 ae0e93d2474b26a764b900c21233f479 364 SUPERFAMILY SSF54106 304 353 1.07E-5 T 28-03-2018 IPR018392 LysM domain SMD44_RS16800 ae0e93d2474b26a764b900c21233f479 364 SMART SM00257 305 354 5.0E-7 T 28-03-2018 IPR018392 LysM domain SMD44_RS16800 ae0e93d2474b26a764b900c21233f479 364 Pfam PF01476 LysM domain 306 352 4.5E-7 T 28-03-2018 IPR018392 LysM domain SMD44_RS16800 ae0e93d2474b26a764b900c21233f479 364 Gene3D G3DSA:3.10.350.10 300 359 7.5E-13 T 28-03-2018 SMD44_RS16800 ae0e93d2474b26a764b900c21233f479 364 SUPERFAMILY SSF53955 40 121 2.78E-26 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS16800 ae0e93d2474b26a764b900c21233f479 364 Gene3D G3DSA:1.10.530.10 16 122 7.4E-27 T 28-03-2018 SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 Pfam PF00550 Phosphopantetheine attachment site 780 846 2.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 ProSitePatterns PS00012 Phosphopantetheine attachment site. 805 820 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 Gene3D G3DSA:3.40.50.720 457 683 1.1E-44 T 28-03-2018 SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 SMART SM00823 Phosphopantetheine attachment site 778 850 3.4E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 SMART SM01294 779 846 1.4E-6 T 28-03-2018 SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 SUPERFAMILY SSF51735 466 691 2.88E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 Gene3D G3DSA:1.10.1200.10 771 878 1.2E-20 T 28-03-2018 SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 Pfam PF08659 KR domain 467 643 2.5E-57 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 SUPERFAMILY SSF51735 410 446 1.48E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 SUPERFAMILY SSF51735 236 375 1.48E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 SUPERFAMILY SSF47336 770 857 2.75E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36785 a0ff943001c9765e1d5392dc26744058 939 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 467 645 4.7E-53 T 28-03-2018 SMD44_RS20405 5c5bfc03651101512dff293f8282cca1 411 Pfam PF01609 Transposase DDE domain 136 356 6.2E-20 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SMD44_RS20405 5c5bfc03651101512dff293f8282cca1 411 SUPERFAMILY SSF53098 94 364 1.14E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS20405 5c5bfc03651101512dff293f8282cca1 411 Gene3D G3DSA:3.90.350.10 122 340 8.5E-14 T 28-03-2018 IPR014736 Transposase, Tn5-like, core SMD44_RS20405 5c5bfc03651101512dff293f8282cca1 411 Pfam PF13006 Insertion element 4 transposase N-terminal 18 115 6.4E-36 T 28-03-2018 IPR024473 Transposase, IS4, N-terminal SMD44_RS23575 5c5bfc03651101512dff293f8282cca1 411 Pfam PF01609 Transposase DDE domain 136 356 6.2E-20 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SMD44_RS23575 5c5bfc03651101512dff293f8282cca1 411 SUPERFAMILY SSF53098 94 364 1.14E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS23575 5c5bfc03651101512dff293f8282cca1 411 Gene3D G3DSA:3.90.350.10 122 340 8.5E-14 T 28-03-2018 IPR014736 Transposase, Tn5-like, core SMD44_RS23575 5c5bfc03651101512dff293f8282cca1 411 Pfam PF13006 Insertion element 4 transposase N-terminal 18 115 6.4E-36 T 28-03-2018 IPR024473 Transposase, IS4, N-terminal SMD44_RS18630 5c5bfc03651101512dff293f8282cca1 411 Pfam PF01609 Transposase DDE domain 136 356 6.2E-20 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SMD44_RS18630 5c5bfc03651101512dff293f8282cca1 411 SUPERFAMILY SSF53098 94 364 1.14E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS18630 5c5bfc03651101512dff293f8282cca1 411 Gene3D G3DSA:3.90.350.10 122 340 8.5E-14 T 28-03-2018 IPR014736 Transposase, Tn5-like, core SMD44_RS18630 5c5bfc03651101512dff293f8282cca1 411 Pfam PF13006 Insertion element 4 transposase N-terminal 18 115 6.4E-36 T 28-03-2018 IPR024473 Transposase, IS4, N-terminal SMD44_RS07800 0375769d9af3a73c31cb655c01fac398 383 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 382 8.4E-104 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS07800 0375769d9af3a73c31cb655c01fac398 383 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 383 134.792 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS07800 0375769d9af3a73c31cb655c01fac398 383 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 20 381 0.0 T 28-03-2018 SMD44_RS07800 0375769d9af3a73c31cb655c01fac398 383 Pfam PF01960 ArgJ family 11 383 1.1E-128 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS07800 0375769d9af3a73c31cb655c01fac398 383 Gene3D G3DSA:3.60.70.12 1 259 1.6E-97 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS07800 0375769d9af3a73c31cb655c01fac398 383 SUPERFAMILY SSF56266 7 379 4.84E-129 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 Gene3D G3DSA:3.40.50.720 2 180 3.5E-41 T 28-03-2018 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 320 8.2E-47 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 PIRSF PIRSF000114 2 333 1.6E-92 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 Gene3D G3DSA:1.10.1040.10 181 328 5.6E-48 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 SUPERFAMILY SSF48179 180 332 6.29E-52 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 6 161 1.2E-46 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 323 35.766 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 SUPERFAMILY SSF51735 5 180 1.02E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 8.4E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 8.4E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 8.4E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 8.4E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 8.4E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS24225 325550ac30b3f15bae8fa8f7584025d9 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 8.4E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 26 901 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 ProSitePatterns PS00450 Aconitase family signature 1. 437 453 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 Gene3D G3DSA:3.20.19.10 663 903 3.6E-92 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 Gene3D G3DSA:3.30.499.10 363 586 2.8E-65 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 Pfam PF00330 Aconitase family (aconitate hydratase) 64 572 5.0E-180 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 270 283 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 141 154 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 284 297 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 363 377 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 165 173 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 194 207 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 503 516 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 441 452 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 PRINTS PR00415 Aconitase family signature 208 223 3.4E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 SUPERFAMILY SSF52016 641 901 5.89E-84 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 Gene3D G3DSA:3.30.499.10 26 230 1.8E-73 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 SUPERFAMILY SSF53732 4 637 5.89E-220 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 Gene3D G3DSA:3.40.1060.10 231 362 6.1E-44 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 Pfam PF00694 Aconitase C-terminal domain 702 831 2.9E-43 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMD44_RS32220 8a8e9fa268cc083fa22470a53c866f7e 904 ProSitePatterns PS01244 Aconitase family signature 2. 503 516 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 5.6E-28 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 Pfam PF00224 Pyruvate kinase, barrel domain 1 336 5.3E-127 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 SUPERFAMILY SSF51621 1 74 2.3E-96 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 SUPERFAMILY SSF51621 154 337 2.3E-96 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 SUPERFAMILY SSF50800 71 164 6.8E-27 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 PRINTS PR01050 Pyruvate kinase family signature 241 265 8.3E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 PRINTS PR01050 Pyruvate kinase family signature 59 75 8.3E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 PRINTS PR01050 Pyruvate kinase family signature 291 309 8.3E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 PRINTS PR01050 Pyruvate kinase family signature 266 290 8.3E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 PRINTS PR01050 Pyruvate kinase family signature 184 198 8.3E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 PRINTS PR01050 Pyruvate kinase family signature 214 240 8.3E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 PRINTS PR01050 Pyruvate kinase family signature 310 326 8.3E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 Gene3D G3DSA:3.20.20.60 158 318 1.0E-62 T 28-03-2018 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 7.1E-167 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 SUPERFAMILY SSF52935 320 470 2.35E-38 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 Gene3D G3DSA:2.40.33.10 75 157 5.8E-27 T 28-03-2018 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 Gene3D G3DSA:3.20.20.60 1 74 9.1E-17 T 28-03-2018 SMD44_RS29220 f53a2f0fe8d9f9bac10e49ded90b223a 476 Gene3D G3DSA:3.40.1380.20 319 471 2.0E-45 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD44_RS21880 537b36b4f4e9a11cc8a72fbb80a52248 318 Gene3D G3DSA:2.60.120.10 20 283 1.0E-78 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS21880 537b36b4f4e9a11cc8a72fbb80a52248 318 PIRSF PIRSF006232 22 318 1.3E-90 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 SMD44_RS21880 537b36b4f4e9a11cc8a72fbb80a52248 318 Pfam PF05726 Pirin C-terminal cupin domain 201 307 6.2E-32 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 SMD44_RS21880 537b36b4f4e9a11cc8a72fbb80a52248 318 SUPERFAMILY SSF51182 24 315 1.24E-82 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS21880 537b36b4f4e9a11cc8a72fbb80a52248 318 Pfam PF02678 Pirin 41 146 6.6E-31 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 Hamap MF_00384 Homoserine kinase [thrB]. 11 300 29.826 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 Gene3D G3DSA:3.30.230.10 9 174 7.5E-34 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 Gene3D G3DSA:3.30.70.890 175 301 1.9E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 PRINTS PR00958 Homoserine kinase signature 18 33 6.7E-34 T 28-03-2018 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 PRINTS PR00958 Homoserine kinase signature 177 194 6.7E-34 T 28-03-2018 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 PRINTS PR00958 Homoserine kinase signature 138 151 6.7E-34 T 28-03-2018 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 PRINTS PR00958 Homoserine kinase signature 101 116 6.7E-34 T 28-03-2018 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 PRINTS PR00958 Homoserine kinase signature 254 269 6.7E-34 T 28-03-2018 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 Pfam PF00288 GHMP kinases N terminal domain 88 151 1.7E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 TIGRFAM TIGR00191 thrB: homoserine kinase 11 281 2.5E-65 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 SUPERFAMILY SSF54211 11 159 9.11E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 SUPERFAMILY SSF55060 173 289 1.24E-28 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 PIRSF PIRSF000676 7 300 7.3E-86 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMD44_RS28810 f01c959316854b71b114e8e155f10527 305 Pfam PF08544 GHMP kinases C terminal 222 280 3.9E-7 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS10960 faead2ff1daaf1d5db4c3b6169aac0e5 313 Gene3D G3DSA:3.10.290.10 7 75 1.3E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS10960 faead2ff1daaf1d5db4c3b6169aac0e5 313 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS10960 faead2ff1daaf1d5db4c3b6169aac0e5 313 Pfam PF00849 RNA pseudouridylate synthase 93 247 7.6E-32 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS10960 faead2ff1daaf1d5db4c3b6169aac0e5 313 SUPERFAMILY SSF55120 82 309 8.02E-69 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS10960 faead2ff1daaf1d5db4c3b6169aac0e5 313 Pfam PF01479 S4 domain 19 62 1.2E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS10960 faead2ff1daaf1d5db4c3b6169aac0e5 313 SUPERFAMILY SSF55174 19 69 4.56E-7 T 28-03-2018 SMD44_RS10960 faead2ff1daaf1d5db4c3b6169aac0e5 313 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 307 3.7E-86 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS10960 faead2ff1daaf1d5db4c3b6169aac0e5 313 Gene3D G3DSA:3.30.2350.10 84 312 1.3E-63 T 28-03-2018 SMD44_RS18870 b26928c76f0513d9c980ad1eaed57224 191 Pfam PF02342 TerD domain 1 187 1.3E-83 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS18870 b26928c76f0513d9c980ad1eaed57224 191 Gene3D G3DSA:2.60.60.30 19 186 9.8E-66 T 28-03-2018 SMD44_RS41745 a20b805573194a686b7e606a9fad7f77 222 Pfam PF02469 Fasciclin domain 100 220 4.2E-31 T 28-03-2018 IPR000782 FAS1 domain SMD44_RS41745 a20b805573194a686b7e606a9fad7f77 222 SMART SM00554 124 221 1.3E-29 T 28-03-2018 IPR000782 FAS1 domain SMD44_RS41745 a20b805573194a686b7e606a9fad7f77 222 SUPERFAMILY SSF82153 84 221 4.45E-35 T 28-03-2018 IPR000782 FAS1 domain SMD44_RS41745 a20b805573194a686b7e606a9fad7f77 222 Gene3D G3DSA:2.30.180.10 87 222 4.1E-33 T 28-03-2018 IPR000782 FAS1 domain SMD44_RS32325 0ab1b90dcea23f053eeff36a793a7374 401 SUPERFAMILY SSF56300 43 319 1.57E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS32325 0ab1b90dcea23f053eeff36a793a7374 401 Gene3D G3DSA:3.60.21.10 31 349 5.9E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS32325 0ab1b90dcea23f053eeff36a793a7374 401 SMART SM00854 43 293 3.5E-64 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA SMD44_RS32325 0ab1b90dcea23f053eeff36a793a7374 401 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 43 291 5.2E-63 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA SMD44_RS08950 047dbd8facfc75db4e2b75101ad7a9e8 398 Gene3D G3DSA:2.40.110.10 141 232 4.0E-34 T 28-03-2018 SMD44_RS08950 047dbd8facfc75db4e2b75101ad7a9e8 398 SUPERFAMILY SSF56645 12 243 8.25E-74 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS08950 047dbd8facfc75db4e2b75101ad7a9e8 398 Gene3D G3DSA:1.10.540.10 2 140 6.4E-33 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS08950 047dbd8facfc75db4e2b75101ad7a9e8 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 142 232 1.1E-23 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS08950 047dbd8facfc75db4e2b75101ad7a9e8 398 Gene3D G3DSA:1.20.140.10 233 397 1.2E-37 T 28-03-2018 SMD44_RS08950 047dbd8facfc75db4e2b75101ad7a9e8 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 138 3.4E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS08950 047dbd8facfc75db4e2b75101ad7a9e8 398 SUPERFAMILY SSF47203 245 394 3.54E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS08950 047dbd8facfc75db4e2b75101ad7a9e8 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 391 2.3E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 118 7.5E-29 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 332 2.3E-43 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 346 33.179 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 SUPERFAMILY SSF55347 130 333 7.97E-65 T 28-03-2018 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 SUPERFAMILY SSF51735 7 158 3.95E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 Gene3D G3DSA:3.40.50.720 1 138 8.5E-36 T 28-03-2018 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 345 4.1E-113 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 SMART SM00859 6 121 1.2E-36 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 PIRSF PIRSF000148 4 350 1.5E-113 T 28-03-2018 SMD44_RS22845 c32517194365c6e20ff5ee09392c959d 353 Gene3D G3DSA:3.30.360.10 139 329 1.9E-81 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Gene3D G3DSA:2.30.130.40 2 121 6.2E-14 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 13 204 7.0E-16 T 28-03-2018 IPR003111 Lon, substrate-binding domain SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 SUPERFAMILY SSF54211 615 793 1.21E-51 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 SMART SM00382 362 507 2.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 585 794 5.1E-75 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 SMART SM00464 12 205 1.8E-16 T 28-03-2018 IPR003111 Lon, substrate-binding domain SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Gene3D G3DSA:1.10.4060.10 124 212 4.8E-8 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 370 389 3.8E-50 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 696 715 3.8E-50 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 745 3.8E-50 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 749 767 3.8E-50 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 615 631 3.8E-50 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Gene3D G3DSA:3.30.230.10 605 795 1.2E-59 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 SUPERFAMILY SSF52540 313 570 2.3E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 TIGRFAM TIGR00763 lon: endopeptidase La 14 793 1.5E-237 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 699 707 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Gene3D G3DSA:3.40.50.300 318 505 1.1E-30 T 28-03-2018 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 PIRSF PIRSF001174 1 798 7.2E-244 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Hamap MF_01973 Lon protease [lon]. 13 795 58.4 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 367 502 1.8E-20 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 SUPERFAMILY SSF88697 13 203 2.01E-19 T 28-03-2018 IPR015947 PUA-like domain SMD44_RS28630 e192485deb2e134daaa54d66459cc06b 805 Gene3D G3DSA:1.10.8.60 506 599 3.4E-25 T 28-03-2018 SMD44_RS27915 a6088c7651ea14c0d3e95c593e1848d5 196 Pfam PF05076 Suppressor of fused protein (SUFU) 29 188 2.0E-34 T 28-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 SUPERFAMILY SSF63380 32 135 6.16E-27 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 Pfam PF00970 Oxidoreductase FAD-binding domain 44 131 8.8E-14 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 Gene3D G3DSA:2.40.30.10 32 133 9.6E-22 T 28-03-2018 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 Gene3D G3DSA:3.40.50.80 134 253 4.1E-16 T 28-03-2018 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 PRINTS PR00409 Phthalate dioxygenase reductase family signature 82 96 4.3E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 PRINTS PR00409 Phthalate dioxygenase reductase family signature 141 160 4.3E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 PRINTS PR00409 Phthalate dioxygenase reductase family signature 220 228 4.3E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 PRINTS PR00409 Phthalate dioxygenase reductase family signature 119 133 4.3E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS08270 268ed3caf353c77df8f30a10c1ec8df8 253 SUPERFAMILY SSF52343 132 252 6.29E-23 T 28-03-2018 SMD44_RS01035 4196e65c81bfea3aa6e9ce17e120d706 505 Pfam PF03972 MmgE/PrpD family 33 470 8.8E-124 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 SMD44_RS01035 4196e65c81bfea3aa6e9ce17e120d706 505 Gene3D G3DSA:1.10.4100.10 7 329 1.1E-80 T 28-03-2018 SMD44_RS01035 4196e65c81bfea3aa6e9ce17e120d706 505 SUPERFAMILY SSF103378 18 485 1.16E-120 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 SMD44_RS26995 965b17c97c87f3654b252dd18c9c0fac 364 SMART SM00044 64 317 0.0012 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMD44_RS26995 965b17c97c87f3654b252dd18c9c0fac 364 Gene3D G3DSA:3.30.70.1230 161 362 6.3E-29 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMD44_RS26995 965b17c97c87f3654b252dd18c9c0fac 364 Pfam PF16701 Adenylate cyclase regulatory domain 23 150 1.4E-9 T 28-03-2018 IPR032026 Adenylate cyclase regulatory domain SMD44_RS26995 965b17c97c87f3654b252dd18c9c0fac 364 SUPERFAMILY SSF55073 177 310 7.85E-32 T 28-03-2018 IPR029787 Nucleotide cyclase SMD44_RS26995 965b17c97c87f3654b252dd18c9c0fac 364 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 179 304 3.3E-14 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 Pfam PF12002 MgsA AAA+ ATPase C terminal 276 440 1.1E-68 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 SMART SM00382 60 181 8.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 Gene3D G3DSA:3.40.50.300 8 165 1.5E-23 T 28-03-2018 SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 Gene3D G3DSA:1.10.3710.10 357 449 4.8E-29 T 28-03-2018 SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 Gene3D G3DSA:1.10.8.60 166 251 3.9E-19 T 28-03-2018 SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 64 168 3.4E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 Pfam PF16193 AAA C-terminal domain 199 275 6.3E-27 T 28-03-2018 IPR032423 AAA C-terminal domain SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 Gene3D G3DSA:1.20.272.10 260 354 1.0E-38 T 28-03-2018 SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 SUPERFAMILY SSF52540 19 244 8.19E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07370 56faa2c619f016ef28f0349777249e8f 450 SUPERFAMILY SSF48019 261 444 8.93E-73 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SMD44_RS07460 d4fcb9b612b308a84f7809d9df4b23e8 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.06 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS07460 d4fcb9b612b308a84f7809d9df4b23e8 250 Pfam PF01709 Transcriptional regulator 5 238 3.2E-89 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS07460 d4fcb9b612b308a84f7809d9df4b23e8 250 Gene3D G3DSA:3.30.70.980 84 177 2.3E-29 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS07460 d4fcb9b612b308a84f7809d9df4b23e8 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 3.0E-97 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS07460 d4fcb9b612b308a84f7809d9df4b23e8 250 Gene3D G3DSA:1.10.10.200 1 78 4.7E-27 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like SMD44_RS07460 d4fcb9b612b308a84f7809d9df4b23e8 250 Gene3D G3DSA:3.30.70.980 178 249 2.0E-13 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS07460 d4fcb9b612b308a84f7809d9df4b23e8 250 SUPERFAMILY SSF75625 3 247 4.71E-88 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 285 1.7E-63 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 Pfam PF01678 Diaminopimelate epimerase 159 280 4.6E-26 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 Pfam PF01678 Diaminopimelate epimerase 7 141 9.6E-34 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 5 287 31.581 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 Gene3D G3DSA:3.10.310.10 144 272 6.6E-39 T 28-03-2018 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 Gene3D G3DSA:3.10.310.10 1 143 1.6E-46 T 28-03-2018 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 SUPERFAMILY SSF54506 5 141 4.76E-31 T 28-03-2018 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 SUPERFAMILY SSF54506 148 286 3.84E-35 T 28-03-2018 SMD44_RS31370 2ab7ec5762248ef5a499d1fb05b47dc5 297 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 76 90 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD44_RS27575 299b6488a2936a3b60379d677ae1e036 84 Gene3D G3DSA:3.30.2310.20 2 84 2.0E-24 T 28-03-2018 SMD44_RS27575 299b6488a2936a3b60379d677ae1e036 84 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 8.0E-39 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 SMD44_RS27575 299b6488a2936a3b60379d677ae1e036 84 SUPERFAMILY SSF143011 3 83 7.72E-27 T 28-03-2018 IPR035095 Toxin RelE-like domain SMD44_RS27575 299b6488a2936a3b60379d677ae1e036 84 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 3.1E-41 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 SMD44_RS17650 cba5207eb07c57454a0c2dc2c925af58 519 Pfam PF00474 Sodium:solute symporter family 33 418 4.2E-27 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS14410 2d38f07316f6015990183fac10762fea 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.8E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS14410 2d38f07316f6015990183fac10762fea 300 Gene3D G3DSA:1.10.10.10 1 86 6.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14410 2d38f07316f6015990183fac10762fea 300 SUPERFAMILY SSF46785 4 113 5.92E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14410 2d38f07316f6015990183fac10762fea 300 Pfam PF03466 LysR substrate binding domain 90 297 1.1E-40 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS14410 2d38f07316f6015990183fac10762fea 300 SUPERFAMILY SSF53850 91 299 2.63E-35 T 28-03-2018 SMD44_RS14410 2d38f07316f6015990183fac10762fea 300 Gene3D G3DSA:3.40.190.10 183 294 8.8E-24 T 28-03-2018 SMD44_RS14410 2d38f07316f6015990183fac10762fea 300 Gene3D G3DSA:3.40.190.10 91 182 1.2E-22 T 28-03-2018 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 SUPERFAMILY SSF46894 150 225 1.46E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 SUPERFAMILY SSF52172 6 138 5.12E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 SMART SM00421 162 219 2.7E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 6.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 6.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 6.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 Gene3D G3DSA:3.40.50.2300 5 137 8.7E-39 T 28-03-2018 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 SMART SM00448 6 119 1.6E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 Pfam PF00072 Response regulator receiver domain 8 120 5.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 Gene3D G3DSA:1.10.10.10 138 224 2.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00365 a8b7f49834e4414d049748f911a9682d 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 219 2.8E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04170 3931bba6b04cdd7f71c65af48d5a2722 347 SUPERFAMILY SSF52540 2 181 4.94E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS04170 3931bba6b04cdd7f71c65af48d5a2722 347 SUPERFAMILY SSF55811 202 330 2.3E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS04170 3931bba6b04cdd7f71c65af48d5a2722 347 PRINTS PR00502 NUDIX hydrolase family signature 240 255 8.1E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS04170 3931bba6b04cdd7f71c65af48d5a2722 347 PRINTS PR00502 NUDIX hydrolase family signature 226 240 8.1E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS04170 3931bba6b04cdd7f71c65af48d5a2722 347 Gene3D G3DSA:3.90.79.10 190 344 1.4E-23 T 28-03-2018 SMD44_RS04170 3931bba6b04cdd7f71c65af48d5a2722 347 Gene3D G3DSA:3.40.50.300 1 189 2.1E-23 T 28-03-2018 SMD44_RS04170 3931bba6b04cdd7f71c65af48d5a2722 347 Pfam PF00293 NUDIX domain 202 325 5.7E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS43185 4410a485c75b8f05f3a95a56feeafb54 410 SUPERFAMILY SSF48452 167 390 1.19E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS43185 4410a485c75b8f05f3a95a56feeafb54 410 SMART SM00028 344 377 22.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS43185 4410a485c75b8f05f3a95a56feeafb54 410 SMART SM00028 212 245 490.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS43185 4410a485c75b8f05f3a95a56feeafb54 410 SMART SM00028 252 285 180.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS43185 4410a485c75b8f05f3a95a56feeafb54 410 SMART SM00028 301 334 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS43185 4410a485c75b8f05f3a95a56feeafb54 410 Gene3D G3DSA:1.25.40.10 135 399 4.2E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS21075 ff225c44a6fb67a59243fdf6e05e123a 205 Gene3D G3DSA:3.40.630.30 4 191 2.7E-16 T 28-03-2018 SMD44_RS21075 ff225c44a6fb67a59243fdf6e05e123a 205 SUPERFAMILY SSF55729 5 141 7.38E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS21075 ff225c44a6fb67a59243fdf6e05e123a 205 Pfam PF00583 Acetyltransferase (GNAT) family 54 136 1.9E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS09290 c444e4846e90f9348570ecb526a8e241 268 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 22 240 6.0E-66 T 28-03-2018 SMD44_RS31005 0732f8ed516f18d3b29864c041ad2f8c 100 Pfam PF06013 Proteins of 100 residues with WXG 9 90 6.2E-14 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMD44_RS31005 0732f8ed516f18d3b29864c041ad2f8c 100 Gene3D G3DSA:1.10.287.1060 5 100 3.0E-16 T 28-03-2018 SMD44_RS31005 0732f8ed516f18d3b29864c041ad2f8c 100 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 10 93 2.2E-15 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMD44_RS31005 0732f8ed516f18d3b29864c041ad2f8c 100 SUPERFAMILY SSF140453 9 99 9.29E-16 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMD44_RS04060 442d98f3d2317297ba25a5b67194e87f 400 Gene3D G3DSA:1.20.1250.20 2 190 1.1E-26 T 28-03-2018 SMD44_RS04060 442d98f3d2317297ba25a5b67194e87f 400 Gene3D G3DSA:1.20.1250.20 191 386 7.8E-22 T 28-03-2018 SMD44_RS04060 442d98f3d2317297ba25a5b67194e87f 400 SUPERFAMILY SSF103473 3 379 3.27E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS04060 442d98f3d2317297ba25a5b67194e87f 400 Pfam PF07690 Major Facilitator Superfamily 8 317 8.3E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS27095 e90717b7233d586dbe8c29203425fb6c 384 PIRSF PIRSF001434 1 384 1.1E-145 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMD44_RS27095 e90717b7233d586dbe8c29203425fb6c 384 Gene3D G3DSA:3.90.1150.10 255 384 1.1E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS27095 e90717b7233d586dbe8c29203425fb6c 384 SUPERFAMILY SSF53383 11 383 6.32E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS27095 e90717b7233d586dbe8c29203425fb6c 384 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 383 5.3E-150 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMD44_RS27095 e90717b7233d586dbe8c29203425fb6c 384 Gene3D G3DSA:3.40.640.10 8 254 1.0E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS18275 b8884f14e3bca35baf253b89b5a1b634 533 SUPERFAMILY SSF52096 232 513 5.91E-77 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS18275 b8884f14e3bca35baf253b89b5a1b634 533 Gene3D G3DSA:3.90.226.10 269 525 1.8E-61 T 28-03-2018 SMD44_RS18275 b8884f14e3bca35baf253b89b5a1b634 533 SUPERFAMILY SSF52096 22 265 4.25E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS18275 b8884f14e3bca35baf253b89b5a1b634 533 Gene3D G3DSA:3.90.226.10 10 268 2.2E-58 T 28-03-2018 SMD44_RS18275 b8884f14e3bca35baf253b89b5a1b634 533 Pfam PF01039 Carboxyl transferase domain 48 521 3.9E-137 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMD44_RS19035 0a7b9da6d6a95540a38c64a59dc2ac5b 226 PIRSF PIRSF003107 1 217 1.1E-55 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SMD44_RS19035 0a7b9da6d6a95540a38c64a59dc2ac5b 226 Gene3D G3DSA:1.20.58.220 1 106 2.8E-22 T 28-03-2018 SMD44_RS19035 0a7b9da6d6a95540a38c64a59dc2ac5b 226 Gene3D G3DSA:1.20.58.220 111 224 1.5E-19 T 28-03-2018 SMD44_RS19035 0a7b9da6d6a95540a38c64a59dc2ac5b 226 Pfam PF01895 PhoU domain 16 103 1.8E-17 T 28-03-2018 IPR026022 PhoU domain SMD44_RS19035 0a7b9da6d6a95540a38c64a59dc2ac5b 226 Pfam PF01895 PhoU domain 121 204 3.6E-13 T 28-03-2018 IPR026022 PhoU domain SMD44_RS19035 0a7b9da6d6a95540a38c64a59dc2ac5b 226 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 1.0E-57 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SMD44_RS19035 0a7b9da6d6a95540a38c64a59dc2ac5b 226 SUPERFAMILY SSF109755 2 216 1.15E-59 T 28-03-2018 SMD44_RS41055 52c287568277132f9a656894ad2f2a7c 436 Pfam PF02333 Phytase 17 230 1.7E-20 T 28-03-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 SMD44_RS41055 52c287568277132f9a656894ad2f2a7c 436 Pfam PF02333 Phytase 252 436 1.6E-26 T 28-03-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 SMD44_RS41055 52c287568277132f9a656894ad2f2a7c 436 Gene3D G3DSA:2.120.10.30 30 436 1.6E-55 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS41055 52c287568277132f9a656894ad2f2a7c 436 SUPERFAMILY SSF50956 35 435 1.31E-57 T 28-03-2018 SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 SUPERFAMILY SSF51735 14 273 4.23E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 Gene3D G3DSA:3.40.50.720 65 274 5.8E-60 T 28-03-2018 SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 Gene3D G3DSA:3.40.50.720 7 64 2.4E-11 T 28-03-2018 SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 272 6.3E-57 T 28-03-2018 SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 2.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 2.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 2.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 235 255 2.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 2.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 2.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 204 8.3E-4 T 28-03-2018 SMD44_RS40960 906ef3b25ea5fce38ba9820720134b5d 274 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 17 273 3.1E-104 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 SUPERFAMILY SSF75553 496 688 7.59E-24 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1196 1.5E-71 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1203 7.7E-275 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 SMART SM00968 512 643 1.8E-23 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1204 22.7 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 Gene3D G3DSA:1.20.120.330 326 492 2.9E-5 T 28-03-2018 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 642 8.4E-23 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 SUPERFAMILY SSF52540 2 207 1.05E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 SUPERFAMILY SSF52540 1005 1195 1.05E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 Gene3D G3DSA:1.20.120.330 667 790 0.043 T 28-03-2018 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 Gene3D G3DSA:3.40.50.300 972 1204 6.8E-32 T 28-03-2018 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 Gene3D G3DSA:3.40.50.300 1 180 4.8E-34 T 28-03-2018 SMD44_RS30395 dfb69d4c30faa3934bbaf847390177e5 1204 PIRSF PIRSF005719 1 1204 5.5E-257 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein SMD44_RS00645 95e265ab859453b0ec3db5e461266b23 545 Gene3D G3DSA:3.40.50.300 260 545 3.7E-42 T 28-03-2018 SMD44_RS00645 95e265ab859453b0ec3db5e461266b23 545 SUPERFAMILY SSF52540 10 216 1.21E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00645 95e265ab859453b0ec3db5e461266b23 545 Gene3D G3DSA:3.40.50.300 3 259 7.6E-52 T 28-03-2018 SMD44_RS00645 95e265ab859453b0ec3db5e461266b23 545 SUPERFAMILY SSF52540 358 541 2.13E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00645 95e265ab859453b0ec3db5e461266b23 545 Pfam PF00005 ABC transporter 362 490 1.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS00645 95e265ab859453b0ec3db5e461266b23 545 Pfam PF00005 ABC transporter 24 172 8.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS00645 95e265ab859453b0ec3db5e461266b23 545 SMART SM00382 368 543 9.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS00645 95e265ab859453b0ec3db5e461266b23 545 SMART SM00382 31 216 7.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16840 fb21be673b6d8b5c459f2eee887b76b1 287 Gene3D G3DSA:3.40.190.10 3 263 2.6E-7 T 28-03-2018 SMD44_RS32130 af9896d96e450f204874981f1f78b0ef 521 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 253 2.3E-110 T 28-03-2018 IPR024740 Hen1, N-terminal SMD44_RS32130 af9896d96e450f204874981f1f78b0ef 521 Pfam PF08242 Methyltransferase domain 309 399 2.6E-12 T 28-03-2018 IPR013217 Methyltransferase type 12 SMD44_RS32130 af9896d96e450f204874981f1f78b0ef 521 SUPERFAMILY SSF53335 290 453 1.49E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS32130 af9896d96e450f204874981f1f78b0ef 521 Gene3D G3DSA:3.40.50.150 285 519 6.3E-42 T 28-03-2018 SMD44_RS32130 af9896d96e450f204874981f1f78b0ef 521 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 3 484 2.7E-204 T 28-03-2018 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial SMD44_RS19500 680858431d6136d2179032540711793a 188 Gene3D G3DSA:3.40.630.30 2 187 2.8E-25 T 28-03-2018 SMD44_RS19500 680858431d6136d2179032540711793a 188 SUPERFAMILY SSF55729 3 174 1.51E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS19500 680858431d6136d2179032540711793a 188 Pfam PF00583 Acetyltransferase (GNAT) family 71 161 2.5E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS08205 a7fb9cac1aee2a4412dd1f58a85c301c 526 SUPERFAMILY SSF53850 32 525 1.7E-93 T 28-03-2018 SMD44_RS08205 a7fb9cac1aee2a4412dd1f58a85c301c 526 Gene3D G3DSA:3.40.190.10 157 295 2.4E-24 T 28-03-2018 SMD44_RS08205 a7fb9cac1aee2a4412dd1f58a85c301c 526 Gene3D G3DSA:3.10.105.10 296 496 2.4E-41 T 28-03-2018 SMD44_RS08205 a7fb9cac1aee2a4412dd1f58a85c301c 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 444 3.5E-71 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS08205 a7fb9cac1aee2a4412dd1f58a85c301c 526 Gene3D G3DSA:3.90.76.10 55 156 5.5E-23 T 28-03-2018 SMD44_RS08205 a7fb9cac1aee2a4412dd1f58a85c301c 526 PIRSF PIRSF002741 5 523 5.0E-63 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS26705 ecbe4279d09300fd5e3177fb120197da 2284 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1786 1865 3.8E-17 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 SMD44_RS26705 ecbe4279d09300fd5e3177fb120197da 2284 SMART SM00306 2026 2135 1.8E-6 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS26705 ecbe4279d09300fd5e3177fb120197da 2284 Pfam PF03534 Salmonella virulence plasmid 65kDa B protein 440 538 1.3E-5 T 28-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 SMD44_RS26705 ecbe4279d09300fd5e3177fb120197da 2284 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1271 1309 7.8E-8 T 28-03-2018 IPR006530 YD repeat SMD44_RS26705 ecbe4279d09300fd5e3177fb120197da 2284 SUPERFAMILY SSF51294 2028 2178 1.44E-17 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS26705 ecbe4279d09300fd5e3177fb120197da 2284 Gene3D G3DSA:2.170.16.10 2004 2177 7.2E-39 T 28-03-2018 SMD44_RS26705 ecbe4279d09300fd5e3177fb120197da 2284 Pfam PF07591 Pretoxin HINT domain 2036 2178 1.9E-17 T 28-03-2018 SMD44_RS26705 ecbe4279d09300fd5e3177fb120197da 2284 Pfam PF05593 RHS Repeat 1271 1304 2.3E-9 T 28-03-2018 IPR031325 RHS repeat SMD44_RS16865 2ff67db69aecac3e3e3020f41feef89d 463 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 259 453 1.0E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS16865 2ff67db69aecac3e3e3020f41feef89d 463 Gene3D G3DSA:3.40.50.1110 245 459 4.3E-29 T 28-03-2018 SMD44_RS16865 2ff67db69aecac3e3e3020f41feef89d 463 SUPERFAMILY SSF52266 254 459 2.5E-44 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS15330 979993cf03b66ef67976fb827a8e488b 681 Pfam PF13506 Glycosyl transferase family 21 227 396 6.7E-21 T 28-03-2018 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|MetaCyc: PWY-7836|MetaCyc: PWY-7838|MetaCyc: PWY-7839|MetaCyc: PWY-7841|Reactome: R-HSA-1660662 SMD44_RS15330 979993cf03b66ef67976fb827a8e488b 681 Gene3D G3DSA:3.90.550.10 161 409 6.6E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS15330 979993cf03b66ef67976fb827a8e488b 681 SUPERFAMILY SSF53448 169 437 5.06E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS09130 ad40a818e8825d707c37c4540ec1f4dc 551 Pfam PF06418 CTP synthase N-terminus 9 272 1.0E-122 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMD44_RS09130 ad40a818e8825d707c37c4540ec1f4dc 551 Gene3D G3DSA:3.40.50.880 292 549 2.8E-64 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS09130 ad40a818e8825d707c37c4540ec1f4dc 551 SUPERFAMILY SSF52317 294 547 1.09E-69 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS09130 ad40a818e8825d707c37c4540ec1f4dc 551 Hamap MF_01227 CTP synthase [pyrG]. 8 546 50.32 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMD44_RS09130 ad40a818e8825d707c37c4540ec1f4dc 551 TIGRFAM TIGR00337 PyrG: CTP synthase 7 541 3.9E-229 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMD44_RS09130 ad40a818e8825d707c37c4540ec1f4dc 551 SUPERFAMILY SSF52540 8 272 3.29E-118 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09130 ad40a818e8825d707c37c4540ec1f4dc 551 Pfam PF00117 Glutamine amidotransferase class-I 307 541 4.3E-46 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS09130 ad40a818e8825d707c37c4540ec1f4dc 551 Gene3D G3DSA:3.40.50.300 1 291 5.8E-128 T 28-03-2018 SMD44_RS14220 dfdfdae2e10b044bb3a48612b68cf39c 162 SUPERFAMILY SSF89623 1 152 2.49E-53 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD44_RS14220 dfdfdae2e10b044bb3a48612b68cf39c 162 Gene3D G3DSA:3.40.1400.10 1 161 1.1E-56 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD44_RS14220 dfdfdae2e10b044bb3a48612b68cf39c 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 1.8E-72 T 28-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 SMD44_RS14220 dfdfdae2e10b044bb3a48612b68cf39c 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 7.4E-55 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD44_RS14220 dfdfdae2e10b044bb3a48612b68cf39c 162 Pfam PF02502 Ribose/Galactose Isomerase 3 142 2.5E-46 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD44_RS14220 dfdfdae2e10b044bb3a48612b68cf39c 162 PIRSF PIRSF005384 1 149 6.0E-51 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD44_RS38475 7566041bece15f2dd7e403be5238b16b 946 Gene3D G3DSA:1.50.10.20 718 940 2.7E-22 T 28-03-2018 SMD44_RS38475 7566041bece15f2dd7e403be5238b16b 946 Gene3D G3DSA:1.50.10.20 131 412 1.1E-13 T 28-03-2018 SMD44_RS38475 7566041bece15f2dd7e403be5238b16b 946 SUPERFAMILY SSF48239 326 473 2.79E-17 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS38475 7566041bece15f2dd7e403be5238b16b 946 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 452 473 0.2 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 SMD44_RS38475 7566041bece15f2dd7e403be5238b16b 946 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 803 821 0.29 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 SMD44_RS38475 7566041bece15f2dd7e403be5238b16b 946 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 757 783 0.98 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 SMD44_RS38475 7566041bece15f2dd7e403be5238b16b 946 Gene3D G3DSA:1.50.10.20 413 717 1.1E-23 T 28-03-2018 SMD44_RS38475 7566041bece15f2dd7e403be5238b16b 946 SUPERFAMILY SSF48239 684 839 1.73E-20 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS06880 0209ab77fe6bcca0773a5402cac566c1 255 SUPERFAMILY SSF51695 14 248 4.71E-61 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS06880 0209ab77fe6bcca0773a5402cac566c1 255 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 20 243 2.6E-38 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD44_RS06880 0209ab77fe6bcca0773a5402cac566c1 255 Gene3D G3DSA:3.20.20.190 16 254 1.6E-61 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS03410 94658cde77feaf241ea9674e6148fa66 537 Pfam PF00501 AMP-binding enzyme 9 438 4.0E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS03410 94658cde77feaf241ea9674e6148fa66 537 Gene3D G3DSA:2.30.38.10 355 432 1.2E-13 T 28-03-2018 SMD44_RS03410 94658cde77feaf241ea9674e6148fa66 537 Gene3D G3DSA:3.40.50.980 3 177 7.1E-38 T 28-03-2018 SMD44_RS03410 94658cde77feaf241ea9674e6148fa66 537 Gene3D G3DSA:3.30.300.30 435 537 2.2E-28 T 28-03-2018 SMD44_RS03410 94658cde77feaf241ea9674e6148fa66 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS03410 94658cde77feaf241ea9674e6148fa66 537 Gene3D G3DSA:3.40.50.980 178 350 1.8E-25 T 28-03-2018 SMD44_RS03410 94658cde77feaf241ea9674e6148fa66 537 SUPERFAMILY SSF56801 4 535 1.09E-116 T 28-03-2018 SMD44_RS03410 94658cde77feaf241ea9674e6148fa66 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 524 2.1E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 Pfam PF09278 MerR, DNA binding 54 119 4.3E-18 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 SUPERFAMILY SSF46955 13 122 1.79E-30 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 24 37 1.2E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 1.2E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 24 1.2E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 Pfam PF00376 MerR family regulatory protein 13 49 5.0E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 Gene3D G3DSA:1.10.1660.10 67 142 3.8E-15 T 28-03-2018 SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 Gene3D G3DSA:1.10.1660.10 8 66 5.0E-22 T 28-03-2018 SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 SMART SM00422 12 80 8.2E-27 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS13390 8a094fc2d8f34c96d469820a1933bff6 152 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 12 151 1.6E-64 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 SMD44_RS11600 990775284e504bf77e82cc75f2e33da4 480 Gene3D G3DSA:1.10.260.40 1 93 0.0026 T 28-03-2018 SMD44_RS11600 990775284e504bf77e82cc75f2e33da4 480 Gene3D G3DSA:1.25.40.10 240 468 1.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 SUPERFAMILY SSF47336 1198 1292 4.71E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:3.40.50.980 669 840 4.2E-44 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Pfam PF00668 Condensation domain 1284 1452 1.1E-19 T 28-03-2018 IPR001242 Condensation domain SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:3.40.50.980 841 991 1.6E-32 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:3.40.50.1820 376 652 1.4E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 ProSitePatterns PS00455 Putative AMP-binding domain signature. 835 846 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Pfam PF00326 Prolyl oligopeptidase family 442 648 1.4E-38 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:2.140.10.30 13 217 2.2E-10 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:2.140.10.30 218 375 1.1E-7 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 SUPERFAMILY SSF52777 1479 1736 1.02E-10 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Pfam PF13193 AMP-binding enzyme C-terminal domain 1101 1184 4.4E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Pfam PF00550 Phosphopantetheine attachment site 1204 1264 7.3E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:1.10.1200.10 1206 1277 4.6E-18 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 SUPERFAMILY SSF56801 671 1214 3.66E-141 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:2.30.38.10 1004 1082 6.4E-23 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 SUPERFAMILY SSF53474 391 643 2.08E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 SUPERFAMILY SSF52777 1280 1466 5.45E-28 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 SMART SM00823 Phosphopantetheine attachment site 1201 1269 6.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 699 1117 7.1E-114 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 SUPERFAMILY SSF82171 76 132 7.06E-20 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 SUPERFAMILY SSF82171 160 379 7.06E-20 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:3.30.559.10 1278 1480 1.4E-30 T 28-03-2018 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Pfam PF00501 AMP-binding enzyme 680 1093 3.5E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS21520 2b53fa5b966bd29a81b2ccbd7200f33e 1736 Gene3D G3DSA:3.30.300.30 1088 1205 8.3E-32 T 28-03-2018 SMD44_RS38120 ff4679f3cb0c44d40e5d856d4086b2cc 496 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 108 124 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 SMD44_RS38120 ff4679f3cb0c44d40e5d856d4086b2cc 496 Pfam PF00135 Carboxylesterase family 6 484 1.1E-96 T 28-03-2018 IPR002018 Carboxylesterase, type B SMD44_RS38120 ff4679f3cb0c44d40e5d856d4086b2cc 496 Gene3D G3DSA:3.40.50.1820 1 496 2.8E-118 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38120 ff4679f3cb0c44d40e5d856d4086b2cc 496 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 179 194 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site SMD44_RS38120 ff4679f3cb0c44d40e5d856d4086b2cc 496 SUPERFAMILY SSF53474 6 495 7.55E-106 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS12485 fdc81d5d245d4514929d1aac00b57851 133 Gene3D G3DSA:2.60.200.20 26 120 5.8E-4 T 28-03-2018 SMD44_RS12485 fdc81d5d245d4514929d1aac00b57851 133 SUPERFAMILY SSF49879 33 83 5.53E-5 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS01005 d0a7dfdeea8aa3c1f73744c7bb5f779b 320 Pfam PF00005 ABC transporter 26 169 8.8E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS01005 d0a7dfdeea8aa3c1f73744c7bb5f779b 320 SMART SM00382 35 218 3.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS01005 d0a7dfdeea8aa3c1f73744c7bb5f779b 320 SUPERFAMILY SSF52540 11 229 3.34E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS01005 d0a7dfdeea8aa3c1f73744c7bb5f779b 320 Gene3D G3DSA:3.40.50.300 9 280 8.1E-60 T 28-03-2018 SMD44_RS01005 d0a7dfdeea8aa3c1f73744c7bb5f779b 320 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 SMART SM00387 320 430 2.0E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 410 5.2E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 Pfam PF00672 HAMP domain 151 193 2.1E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 SUPERFAMILY SSF47384 182 255 7.85E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 Gene3D G3DSA:1.10.287.130 189 241 2.7E-10 T 28-03-2018 SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 256 3.2E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 SUPERFAMILY SSF55874 315 419 3.01E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 SUPERFAMILY SSF158472 149 194 1.24E-8 T 28-03-2018 SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 Gene3D G3DSA:3.30.565.10 242 420 1.8E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 SMART SM00388 199 257 3.4E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS17250 428a42844a6bc5af0373e5f54a14bf17 454 SMART SM00304 146 198 1.4E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS33740 8652b4c797101d2540aac7825cdc7b18 119 Pfam PF03861 ANTAR domain 37 90 2.7E-10 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS33740 8652b4c797101d2540aac7825cdc7b18 119 PIRSF PIRSF010636 24 119 1.8E-20 T 28-03-2018 IPR024189 ANTAR transcription anti-termination regulator SMD44_RS33740 8652b4c797101d2540aac7825cdc7b18 119 Gene3D G3DSA:1.10.10.10 39 92 1.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33740 8652b4c797101d2540aac7825cdc7b18 119 SUPERFAMILY SSF52172 29 90 4.22E-5 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS33740 8652b4c797101d2540aac7825cdc7b18 119 SMART SM01012 35 90 3.8E-9 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS08935 09198df5bd46ae5fea126dd138b04686 318 Gene3D G3DSA:3.40.190.10 196 308 1.4E-13 T 28-03-2018 SMD44_RS08935 09198df5bd46ae5fea126dd138b04686 318 Gene3D G3DSA:3.40.190.10 48 195 2.1E-26 T 28-03-2018 SMD44_RS08935 09198df5bd46ae5fea126dd138b04686 318 SUPERFAMILY SSF53850 67 300 4.17E-47 T 28-03-2018 SMD44_RS08935 09198df5bd46ae5fea126dd138b04686 318 SUPERFAMILY SSF53850 11 28 4.17E-47 T 28-03-2018 SMD44_RS08935 09198df5bd46ae5fea126dd138b04686 318 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 79 300 1.8E-39 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS08935 09198df5bd46ae5fea126dd138b04686 318 SMART SM00062 75 303 3.3E-31 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS43920 e62a8fd565b1d52ce74b4046a04013bc 287 Pfam PF01068 ATP dependent DNA ligase domain 21 192 1.5E-20 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMD44_RS43920 e62a8fd565b1d52ce74b4046a04013bc 287 Gene3D G3DSA:3.30.1490.70 135 195 1.2E-12 T 28-03-2018 SMD44_RS43920 e62a8fd565b1d52ce74b4046a04013bc 287 Gene3D G3DSA:3.30.470.30 2 134 3.2E-20 T 28-03-2018 SMD44_RS43920 e62a8fd565b1d52ce74b4046a04013bc 287 SUPERFAMILY SSF56091 3 188 1.46E-32 T 28-03-2018 SMD44_RS24300 2eda3652e28db9e6dae3ee89577fb0fe 199 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 14 194 5.7E-40 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 SMD44_RS24300 2eda3652e28db9e6dae3ee89577fb0fe 199 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 194 1.5E-21 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS24300 2eda3652e28db9e6dae3ee89577fb0fe 199 Gene3D G3DSA:1.20.120.450 2 139 2.1E-14 T 28-03-2018 SMD44_RS24300 2eda3652e28db9e6dae3ee89577fb0fe 199 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 131 1.2E-8 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS24300 2eda3652e28db9e6dae3ee89577fb0fe 199 SUPERFAMILY SSF109854 8 137 3.43E-16 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 PRINTS PR01021 OMPA domain signature 132 147 6.9E-7 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 PRINTS PR01021 OMPA domain signature 147 163 6.9E-7 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 PRINTS PR01021 OMPA domain signature 102 124 6.9E-7 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 147 164 2.1E-6 T 28-03-2018 SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 185 205 2.1E-6 T 28-03-2018 SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 165 184 2.1E-6 T 28-03-2018 SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 Gene3D G3DSA:3.30.1330.60 58 211 1.8E-29 T 28-03-2018 IPR006665 OmpA-like domain SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 SUPERFAMILY SSF103088 90 202 3.92E-28 T 28-03-2018 IPR006665 OmpA-like domain SMD44_RS27390 15eb24139bbd9514629945f2bbe4be11 214 Pfam PF00691 OmpA family 102 196 6.1E-14 T 28-03-2018 IPR006665 OmpA-like domain SMD44_RS38625 cd303c1b70dd9945bfa6661e5ae688ee 315 Gene3D G3DSA:3.40.50.170 1 204 3.1E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS38625 cd303c1b70dd9945bfa6661e5ae688ee 315 Pfam PF02911 Formyl transferase, C-terminal domain 207 306 9.4E-18 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS38625 cd303c1b70dd9945bfa6661e5ae688ee 315 Pfam PF00551 Formyl transferase 1 170 1.1E-32 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS38625 cd303c1b70dd9945bfa6661e5ae688ee 315 Gene3D G3DSA:3.10.25.10 206 313 4.6E-22 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS38625 cd303c1b70dd9945bfa6661e5ae688ee 315 SUPERFAMILY SSF53328 1 204 5.1E-58 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS38625 cd303c1b70dd9945bfa6661e5ae688ee 315 SUPERFAMILY SSF50486 206 309 2.35E-19 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMD44_RS41150 9cb7754b6542aa0388c0ef5f99d427d2 108 SUPERFAMILY SSF158560 3 98 1.96E-28 T 28-03-2018 SMD44_RS41150 9cb7754b6542aa0388c0ef5f99d427d2 108 Pfam PF06304 Protein of unknown function (DUF1048) 5 99 1.5E-32 T 28-03-2018 IPR008316 Uncharacterised conserved protein UCP029876 SMD44_RS41150 9cb7754b6542aa0388c0ef5f99d427d2 108 Gene3D G3DSA:1.10.1900.10 18 100 4.5E-29 T 28-03-2018 SMD44_RS27055 7bad7e74e689b680c19bb00a0877b53a 262 SUPERFAMILY SSF46458 105 216 3.08E-22 T 28-03-2018 IPR009050 Globin-like SMD44_RS27055 7bad7e74e689b680c19bb00a0877b53a 262 Gene3D G3DSA:3.30.70.100 1 101 1.2E-17 T 28-03-2018 SMD44_RS27055 7bad7e74e689b680c19bb00a0877b53a 262 Gene3D G3DSA:1.10.490.10 102 234 1.5E-24 T 28-03-2018 SMD44_RS27055 7bad7e74e689b680c19bb00a0877b53a 262 Pfam PF03992 Antibiotic biosynthesis monooxygenase 9 79 6.8E-9 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD44_RS27055 7bad7e74e689b680c19bb00a0877b53a 262 Pfam PF01152 Bacterial-like globin 109 214 3.3E-12 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 SMD44_RS27055 7bad7e74e689b680c19bb00a0877b53a 262 SUPERFAMILY SSF54909 1 98 1.73E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS13620 414d1a0d9c304584118a2b06b7b9ee4c 143 Pfam PF12680 SnoaL-like domain 20 123 1.5E-13 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS13620 414d1a0d9c304584118a2b06b7b9ee4c 143 Gene3D G3DSA:3.10.450.50 4 140 5.9E-26 T 28-03-2018 SMD44_RS13620 414d1a0d9c304584118a2b06b7b9ee4c 143 SUPERFAMILY SSF54427 10 133 4.01E-32 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS40100 b5878a4ceca863443985a9aa2257bb25 540 Pfam PF07364 Metallopeptidase family M81 20 308 7.4E-99 T 28-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal SMD44_RS40100 b5878a4ceca863443985a9aa2257bb25 540 PIRSF PIRSF012702 16 522 8.9E-146 T 28-03-2018 IPR009197 Microcystin LR degradation protein MlrC SMD44_RS40100 b5878a4ceca863443985a9aa2257bb25 540 Pfam PF07171 MlrC C-terminus 318 503 3.1E-54 T 28-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal SMD44_RS27345 4705e0a13d40492fdf9f5336f45c4af3 554 SUPERFAMILY SSF52172 48 134 4.39E-8 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS27345 4705e0a13d40492fdf9f5336f45c4af3 554 Gene3D G3DSA:3.40.50.300 155 395 3.0E-31 T 28-03-2018 SMD44_RS27345 4705e0a13d40492fdf9f5336f45c4af3 554 Gene3D G3DSA:3.40.50.2300 3 136 2.0E-6 T 28-03-2018 SMD44_RS27345 4705e0a13d40492fdf9f5336f45c4af3 554 Pfam PF07811 TadE-like protein 435 477 1.7E-9 T 28-03-2018 IPR012495 TadE-like SMD44_RS27345 4705e0a13d40492fdf9f5336f45c4af3 554 Pfam PF13614 AAA domain 158 319 8.5E-11 T 28-03-2018 IPR025669 AAA domain SMD44_RS27345 4705e0a13d40492fdf9f5336f45c4af3 554 SUPERFAMILY SSF52540 158 393 2.1E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 480 1.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 540 1.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 522 1.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 SUPERFAMILY SSF55874 388 542 8.38E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 Gene3D G3DSA:3.30.565.10 389 552 1.2E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 SMART SM00387 429 543 7.6E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 Gene3D G3DSA:1.10.287.130 290 363 2.1E-17 T 28-03-2018 SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 SMART SM00304 230 292 2.1E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 430 541 1.7E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 Pfam PF00672 HAMP domain 233 286 4.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 SMART SM00388 300 367 1.1E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 Pfam PF00512 His Kinase A (phospho-acceptor) domain 302 365 4.8E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS20315 0938ff3cbd37ab20c53d49213e97dd60 559 SUPERFAMILY SSF47384 285 366 2.16E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS30040 6912e2a18c8da07bdfb970d08d3e3887 232 Pfam PF00547 Urease, gamma subunit 2 99 6.8E-34 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30040 6912e2a18c8da07bdfb970d08d3e3887 232 Gene3D G3DSA:3.30.280.10 2 99 5.1E-35 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30040 6912e2a18c8da07bdfb970d08d3e3887 232 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 5.0E-30 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30040 6912e2a18c8da07bdfb970d08d3e3887 232 Gene3D G3DSA:2.10.150.10 122 232 3.2E-33 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30040 6912e2a18c8da07bdfb970d08d3e3887 232 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 31 99 7.0E-29 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30040 6912e2a18c8da07bdfb970d08d3e3887 232 Pfam PF00699 Urease beta subunit 123 202 6.0E-27 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30040 6912e2a18c8da07bdfb970d08d3e3887 232 SUPERFAMILY SSF54111 2 100 1.44E-30 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS30040 6912e2a18c8da07bdfb970d08d3e3887 232 SUPERFAMILY SSF51278 120 228 6.41E-35 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS15715 e3241f81fe0582eba74b976975a34f95 812 Gene3D G3DSA:2.60.120.260 435 610 5.5E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS15715 e3241f81fe0582eba74b976975a34f95 812 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 174 486 2.0E-81 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD44_RS15715 e3241f81fe0582eba74b976975a34f95 812 Pfam PF05547 Immune inhibitor A peptidase M6 105 804 3.8E-225 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD44_RS15715 e3241f81fe0582eba74b976975a34f95 812 Gene3D G3DSA:3.40.390.10 164 434 1.4E-6 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD44_RS15715 e3241f81fe0582eba74b976975a34f95 812 PIRSF PIRSF007519 1 812 1.1E-221 T 28-03-2018 IPR012300 Peptidase M6, InhA SMD44_RS15715 e3241f81fe0582eba74b976975a34f95 812 SUPERFAMILY SSF55486 355 434 5.64E-16 T 28-03-2018 SMD44_RS15715 e3241f81fe0582eba74b976975a34f95 812 SUPERFAMILY SSF55486 242 301 5.64E-16 T 28-03-2018 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 215 237 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 172 187 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 342 357 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 109 120 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 155 171 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 314 341 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 364 373 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 373 384 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00359 B-class P450 signature 296 307 8.0E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 Pfam PF00067 Cytochrome P450 214 282 5.9E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 Pfam PF00067 Cytochrome P450 292 383 4.0E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00385 P450 superfamily signature 364 373 1.4E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00385 P450 superfamily signature 373 384 1.4E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00385 P450 superfamily signature 296 307 1.4E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 PRINTS PR00385 P450 superfamily signature 261 278 1.4E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 366 375 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 Gene3D G3DSA:1.10.630.10 18 424 6.2E-61 T 28-03-2018 SMD44_RS36470 bfa1f7066f0791372422f6a86c39de91 426 SUPERFAMILY SSF48264 57 421 6.29E-74 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS01820 cf50417a8a29fe367baf98a816710dc2 321 Pfam PF00144 Beta-lactamase 12 276 1.8E-49 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS01820 cf50417a8a29fe367baf98a816710dc2 321 SUPERFAMILY SSF56601 14 278 7.34E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS01820 cf50417a8a29fe367baf98a816710dc2 321 Gene3D G3DSA:3.40.710.10 8 320 3.7E-63 T 28-03-2018 SMD44_RS31040 e4544b3b69a7a5d747f8bb6f649a45be 459 Pfam PF00675 Insulinase (Peptidase family M16) 45 192 2.9E-36 T 28-03-2018 IPR011765 Peptidase M16, N-terminal SMD44_RS31040 e4544b3b69a7a5d747f8bb6f649a45be 459 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 66 89 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 SMD44_RS31040 e4544b3b69a7a5d747f8bb6f649a45be 459 SUPERFAMILY SSF63411 263 450 1.16E-47 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD44_RS31040 e4544b3b69a7a5d747f8bb6f649a45be 459 Pfam PF05193 Peptidase M16 inactive domain 199 380 2.1E-45 T 28-03-2018 IPR007863 Peptidase M16, C-terminal SMD44_RS31040 e4544b3b69a7a5d747f8bb6f649a45be 459 Gene3D G3DSA:3.30.830.10 13 247 8.1E-58 T 28-03-2018 SMD44_RS31040 e4544b3b69a7a5d747f8bb6f649a45be 459 Gene3D G3DSA:3.30.830.10 278 452 1.5E-47 T 28-03-2018 SMD44_RS31040 e4544b3b69a7a5d747f8bb6f649a45be 459 SUPERFAMILY SSF63411 34 238 1.26E-59 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD44_RS13680 8988bb183a962fbd0fa979712e94ebbf 702 SUPERFAMILY SSF82866 485 679 1.22E-25 T 28-03-2018 SMD44_RS13680 8988bb183a962fbd0fa979712e94ebbf 702 Gene3D G3DSA:1.20.1640.10 137 341 3.8E-36 T 28-03-2018 SMD44_RS13680 8988bb183a962fbd0fa979712e94ebbf 702 Gene3D G3DSA:1.20.1640.10 453 677 1.6E-26 T 28-03-2018 SMD44_RS13680 8988bb183a962fbd0fa979712e94ebbf 702 Pfam PF03176 MMPL family 49 373 2.8E-64 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS13680 8988bb183a962fbd0fa979712e94ebbf 702 Pfam PF03176 MMPL family 478 680 4.1E-41 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS13680 8988bb183a962fbd0fa979712e94ebbf 702 SUPERFAMILY SSF82866 116 344 1.29E-33 T 28-03-2018 SMD44_RS13680 8988bb183a962fbd0fa979712e94ebbf 702 Gene3D G3DSA:3.40.50.261 27 136 0.099 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS29105 72d284eed7230c870898284eda8a9a81 659 SUPERFAMILY SSF81296 560 658 7.56E-17 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS29105 72d284eed7230c870898284eda8a9a81 659 SUPERFAMILY SSF50965 56 139 2.48E-6 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller SMD44_RS29105 72d284eed7230c870898284eda8a9a81 659 Gene3D G3DSA:2.60.40.10 564 659 1.6E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS29105 72d284eed7230c870898284eda8a9a81 659 Pfam PF09118 Domain of unknown function (DUF1929) 578 658 2.5E-18 T 28-03-2018 IPR015202 Galactose oxidase-like, Early set domain SMD44_RS29105 72d284eed7230c870898284eda8a9a81 659 SUPERFAMILY SSF50965 273 557 1.44E-25 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller SMD44_RS29105 72d284eed7230c870898284eda8a9a81 659 Gene3D G3DSA:2.130.10.80 51 563 1.1E-71 T 28-03-2018 IPR015916 Galactose oxidase, beta-propeller SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 Pfam PF00067 Cytochrome P450 190 395 6.6E-25 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 Gene3D G3DSA:1.10.630.10 21 428 6.9E-75 T 28-03-2018 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00359 B-class P450 signature 155 171 3.3E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00359 B-class P450 signature 375 386 3.3E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00359 B-class P450 signature 300 311 3.3E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00359 B-class P450 signature 317 344 3.3E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00359 B-class P450 signature 345 360 3.3E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00359 B-class P450 signature 108 119 3.3E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00359 B-class P450 signature 172 187 3.3E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00359 B-class P450 signature 366 375 3.3E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 368 377 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 SUPERFAMILY SSF48264 29 426 6.94E-92 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00385 P450 superfamily signature 366 375 5.6E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00385 P450 superfamily signature 375 386 5.6E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00385 P450 superfamily signature 300 311 5.6E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS02565 750d56cb55b716ec40b2b0bbdf1d9ff6 429 PRINTS PR00385 P450 superfamily signature 265 282 5.6E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS33745 fd1fcb026a942884941b3632646bc108 118 Gene3D G3DSA:3.90.50.10 1 117 8.7E-14 T 28-03-2018 SMD44_RS33745 fd1fcb026a942884941b3632646bc108 118 SUPERFAMILY SSF50346 2 108 1.61E-17 T 28-03-2018 IPR011033 PRC-barrel-like SMD44_RS33745 fd1fcb026a942884941b3632646bc108 118 Pfam PF05239 PRC-barrel domain 7 75 3.1E-5 T 28-03-2018 IPR027275 PRC-barrel domain SMD44_RS30995 b1b45e35a9c2daca30cef8298b41d2fa 365 Pfam PF00082 Subtilase family 12 264 3.3E-33 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS30995 b1b45e35a9c2daca30cef8298b41d2fa 365 Gene3D G3DSA:3.40.50.200 1 275 2.6E-61 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS30995 b1b45e35a9c2daca30cef8298b41d2fa 365 PRINTS PR00723 Subtilisin serine protease family (S8) signature 213 229 1.1E-6 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS30995 b1b45e35a9c2daca30cef8298b41d2fa 365 PRINTS PR00723 Subtilisin serine protease family (S8) signature 12 31 1.1E-6 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS30995 b1b45e35a9c2daca30cef8298b41d2fa 365 PRINTS PR00723 Subtilisin serine protease family (S8) signature 50 63 1.1E-6 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS30995 b1b45e35a9c2daca30cef8298b41d2fa 365 SUPERFAMILY SSF52743 1 270 9.03E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS26750 4031bbb3d5a3357cebb456518b7d0d82 73 Pfam PF14433 SUKH-3 immunity protein 11 58 3.6E-6 T 28-03-2018 IPR025850 SUKH-3 immunity protein SMD44_RS22365 bfd626ae3ac482ff3465d07d576ccfa5 147 SUPERFAMILY SSF88723 5 133 3.64E-17 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS22365 bfd626ae3ac482ff3465d07d576ccfa5 147 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 136 11.515 T 28-03-2018 IPR022907 VapC family GO:0004540 SMD44_RS22365 bfd626ae3ac482ff3465d07d576ccfa5 147 Pfam PF01850 PIN domain 5 129 2.5E-12 T 28-03-2018 IPR002716 PIN domain SMD44_RS22365 bfd626ae3ac482ff3465d07d576ccfa5 147 Gene3D G3DSA:3.40.50.1010 4 139 9.6E-18 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 PRINTS PR00143 Citrate synthase signature 187 215 2.8E-26 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 PRINTS PR00143 Citrate synthase signature 165 180 2.8E-26 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 PRINTS PR00143 Citrate synthase signature 319 333 2.8E-26 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 PRINTS PR00143 Citrate synthase signature 240 260 2.8E-26 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 PRINTS PR00143 Citrate synthase signature 299 315 2.8E-26 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 SUPERFAMILY SSF48256 7 358 1.05E-95 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 Gene3D G3DSA:1.10.230.10 229 319 8.2E-24 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 ProSitePatterns PS00480 Citrate synthase signature. 247 259 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 Gene3D G3DSA:1.10.580.10 1 72 1.7E-12 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 Gene3D G3DSA:1.10.580.10 73 228 1.4E-36 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMD44_RS18250 c3572d4690e7ffa1a5076d50f9346e00 371 Pfam PF00285 Citrate synthase, C-terminal domain 12 348 4.4E-85 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS32990 1c83d7e03090e3170697961bf650bf20 147 SUPERFAMILY SSF55874 60 139 3.9E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS32990 1c83d7e03090e3170697961bf650bf20 147 Pfam PF13581 Histidine kinase-like ATPase domain 31 140 1.1E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS32990 1c83d7e03090e3170697961bf650bf20 147 Gene3D G3DSA:3.30.565.10 20 146 3.6E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 Gene3D G3DSA:3.30.420.40 3 252 2.2E-90 T 28-03-2018 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 Hamap MF_00186 Glycerol kinase [glpK]. 6 501 55.521 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 PIRSF PIRSF000538 6 505 7.8E-167 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 9 255 1.6E-75 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 SUPERFAMILY SSF53067 258 500 1.88E-82 T 28-03-2018 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 7 500 1.6E-221 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 Gene3D G3DSA:3.30.420.40 253 504 1.4E-79 T 28-03-2018 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 264 454 1.5E-64 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 SUPERFAMILY SSF53067 8 258 4.05E-90 T 28-03-2018 SMD44_RS06720 c4b0dc13f4f15e6c6c966b805ab38de5 506 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 366 386 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD44_RS12660 bbfd11e8aecfeb22a69cff4a050d993d 860 Pfam PF15608 PELOTA RNA binding domain 763 842 8.0E-35 T 28-03-2018 IPR028157 PELOTA RNA-binding domain SMD44_RS12660 bbfd11e8aecfeb22a69cff4a050d993d 860 Pfam PF15609 Phosphoribosyl transferase 46 233 4.4E-69 T 28-03-2018 SMD44_RS12660 bbfd11e8aecfeb22a69cff4a050d993d 860 Pfam PF12500 TRSP domain C terminus to PRTase_2 282 435 3.6E-46 T 28-03-2018 IPR022537 TRSP domain SMD44_RS12660 bbfd11e8aecfeb22a69cff4a050d993d 860 Gene3D G3DSA:3.40.50.2020 47 237 4.1E-15 T 28-03-2018 SMD44_RS12660 bbfd11e8aecfeb22a69cff4a050d993d 860 Pfam PF11202 Phosphoribosyl transferase (PRTase) 483 736 6.8E-106 T 28-03-2018 IPR011215 Phosphoribosyl transferase SMD44_RS06425 e0b3170e33e338b8109729e4ab0dd4a4 301 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 121 1.1E-14 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS06425 e0b3170e33e338b8109729e4ab0dd4a4 301 SUPERFAMILY SSF55347 123 258 2.94E-34 T 28-03-2018 SMD44_RS06425 e0b3170e33e338b8109729e4ab0dd4a4 301 Gene3D G3DSA:3.30.360.10 135 297 1.5E-11 T 28-03-2018 SMD44_RS06425 e0b3170e33e338b8109729e4ab0dd4a4 301 Gene3D G3DSA:3.40.50.720 1 134 3.5E-31 T 28-03-2018 SMD44_RS06425 e0b3170e33e338b8109729e4ab0dd4a4 301 SUPERFAMILY SSF51735 1 137 2.15E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS30480 e043d466a7e585daa7cd03c179ad917a 79 Pfam PF13083 KH domain 3 65 3.7E-19 T 28-03-2018 SMD44_RS30480 e043d466a7e585daa7cd03c179ad917a 79 Gene3D G3DSA:3.30.300.20 1 76 1.7E-14 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS30480 e043d466a7e585daa7cd03c179ad917a 79 SUPERFAMILY SSF54814 16 62 1.9E-8 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD44_RS30480 e043d466a7e585daa7cd03c179ad917a 79 Hamap MF_00088 UPF0109 protein . 2 73 21.613 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 SUPERFAMILY SSF51735 6 250 5.76E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.3E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.4E-6 T 28-03-2018 SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 5.3E-62 T 28-03-2018 SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 Gene3D G3DSA:3.40.50.720 159 250 5.2E-24 T 28-03-2018 SMD44_RS06465 d03d8ddfe4d27c22b66b9792c6cece01 253 Gene3D G3DSA:3.40.50.720 3 158 7.5E-49 T 28-03-2018 SMD44_RS07825 4aba50625fbde5fa1181d2e13330fafd 516 SUPERFAMILY SSF53474 424 475 7.88E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS07825 4aba50625fbde5fa1181d2e13330fafd 516 SUPERFAMILY SSF53474 340 391 7.88E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS07825 4aba50625fbde5fa1181d2e13330fafd 516 SUPERFAMILY SSF53474 86 139 7.88E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS07825 4aba50625fbde5fa1181d2e13330fafd 516 SUPERFAMILY SSF53474 175 241 7.88E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS07825 4aba50625fbde5fa1181d2e13330fafd 516 Pfam PF08386 TAP-like protein 406 510 2.1E-12 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD44_RS07825 4aba50625fbde5fa1181d2e13330fafd 516 Pfam PF00561 alpha/beta hydrolase fold 95 287 1.4E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS07825 4aba50625fbde5fa1181d2e13330fafd 516 Gene3D G3DSA:3.40.50.1820 9 487 2.0E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 3.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 3.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 3.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 SUPERFAMILY SSF52172 7 182 4.07E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 216 2.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 Gene3D G3DSA:1.10.10.10 133 226 3.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 SMART SM00448 8 121 4.6E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 SMART SM00421 159 216 4.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 Gene3D G3DSA:3.40.50.2300 7 132 8.9E-36 T 28-03-2018 SMD44_RS17505 5c1aaad9188a5984219c33548cbecaef 233 Pfam PF00072 Response regulator receiver domain 10 122 4.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS05845 9caeb8c4b0133eec8bc2c6acd1a4d887 113 SUPERFAMILY SSF54593 2 112 9.67E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS05845 9caeb8c4b0133eec8bc2c6acd1a4d887 113 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 108 6.9E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS05845 9caeb8c4b0133eec8bc2c6acd1a4d887 113 Gene3D G3DSA:3.10.180.10 1 113 5.5E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS14200 5a82daa23da324d703d73e3bfcb4e0b8 394 SMART SM00331 183 392 1.4E-10 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS14200 5a82daa23da324d703d73e3bfcb4e0b8 394 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 210 392 1.2E-30 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS14200 5a82daa23da324d703d73e3bfcb4e0b8 394 Gene3D G3DSA:3.60.40.10 164 393 5.1E-13 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS05550 b33a79248bed894cf08ed00ebd338621 273 SUPERFAMILY SSF47413 32 85 1.44E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS05550 b33a79248bed894cf08ed00ebd338621 273 Gene3D G3DSA:1.10.260.40 1 88 1.3E-10 T 28-03-2018 SMD44_RS05550 b33a79248bed894cf08ed00ebd338621 273 Pfam PF13560 Helix-turn-helix domain 7 83 4.6E-9 T 28-03-2018 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 Gene3D G3DSA:3.40.1110.10 335 467 2.7E-21 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 35 704 40.775 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 395 625 1.3E-41 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 93 361 2.0E-30 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 Gene3D G3DSA:2.70.150.10 14 227 2.9E-25 T 28-03-2018 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 SUPERFAMILY SSF81665 58 124 1.06E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 SUPERFAMILY SSF81665 227 318 1.06E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 SUPERFAMILY SSF81653 135 226 3.14E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 Pfam PF00122 E1-E2 ATPase 128 302 4.3E-35 T 28-03-2018 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 36 700 0.0 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 SUPERFAMILY SSF56784 371 424 1.57E-38 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 SUPERFAMILY SSF56784 459 583 1.57E-38 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 SUPERFAMILY SSF56784 312 336 1.57E-38 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 Pfam PF00702 haloacid dehalogenase-like hydrolase 321 554 3.0E-32 T 28-03-2018 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 Gene3D G3DSA:3.40.50.1000 468 596 2.1E-34 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 497 3.5E-25 T 28-03-2018 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 173 187 3.5E-25 T 28-03-2018 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 3.5E-25 T 28-03-2018 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 563 575 3.5E-25 T 28-03-2018 SMD44_RS31760 f8256b5d5903e317a5e711c612094cd7 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 540 559 3.5E-25 T 28-03-2018 SMD44_RS39670 75ef206d5caa33904e1fc7aa9a9e2167 212 Pfam PF03559 NDP-hexose 2,3-dehydratase 26 171 3.2E-49 T 28-03-2018 IPR005212 NDP-hexose 2,3-dehydratase SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 Gene3D G3DSA:3.20.20.80 255 625 1.4E-84 T 28-03-2018 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 SUPERFAMILY SSF49384 49 151 2.23E-31 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 SUPERFAMILY SSF54556 522 581 2.33E-13 T 28-03-2018 IPR029070 Chitinase insertion domain SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 Pfam PF00704 Glycosyl hydrolases family 18 260 610 1.4E-75 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 SUPERFAMILY SSF51445 255 520 1.05E-82 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 SUPERFAMILY SSF51445 580 623 1.05E-82 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 SUPERFAMILY SSF49265 159 242 1.61E-14 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 118 131 - T 28-03-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 SMART SM00060 161 235 4.8E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 ProSitePatterns PS01095 Chitinases family 18 active site. 391 399 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 SMART SM00637 53 150 5.9E-44 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 Pfam PF00553 Cellulose binding domain 53 150 8.0E-33 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 SMART SM00636 257 610 5.3E-119 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 Gene3D G3DSA:2.60.40.10 158 245 6.0E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS28910 2daec5bca20a632b99adda232eec100e 625 Gene3D G3DSA:2.60.40.290 44 150 2.8E-34 T 28-03-2018 SMD44_RS11720 cab5867d046959e0c962b37757309ec3 347 Gene3D G3DSA:3.40.50.1980 179 343 2.2E-37 T 28-03-2018 SMD44_RS11720 cab5867d046959e0c962b37757309ec3 347 SUPERFAMILY SSF53807 58 340 1.81E-45 T 28-03-2018 SMD44_RS11720 cab5867d046959e0c962b37757309ec3 347 Pfam PF01497 Periplasmic binding protein 63 318 1.0E-40 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS11720 cab5867d046959e0c962b37757309ec3 347 Gene3D G3DSA:3.40.50.1980 41 178 3.8E-30 T 28-03-2018 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SMART SM00487 614 808 1.1E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 PRINTS PR00379 Intein signature 425 437 6.9E-5 T 28-03-2018 IPR006142 Intein GO:0016539 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 PRINTS PR00379 Intein signature 523 535 6.9E-5 T 28-03-2018 IPR006142 Intein GO:0016539 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 PRINTS PR00379 Intein signature 551 566 6.9E-5 T 28-03-2018 IPR006142 Intein GO:0016539 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Gene3D G3DSA:3.40.50.300 644 794 1.5E-19 T 28-03-2018 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Pfam PF00270 DEAD/DEAH box helicase 644 784 1.2E-9 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SUPERFAMILY SSF55608 506 605 2.83E-16 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Pfam PF00271 Helicase conserved C-terminal domain 905 976 3.1E-17 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Gene3D G3DSA:2.40.50.140 46 147 3.1E-21 T 28-03-2018 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SUPERFAMILY SSF50249 15 183 1.95E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SUPERFAMILY SSF52540 189 305 2.19E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SUPERFAMILY SSF52540 658 848 1.92E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SUPERFAMILY SSF52540 892 990 1.92E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Pfam PF14528 LAGLIDADG-like domain 523 567 3.9E-5 T 28-03-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SMART SM00490 892 977 2.3E-22 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Gene3D G3DSA:3.10.28.10 519 604 1.6E-11 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Gene3D G3DSA:3.40.50.300 813 1018 4.7E-30 T 28-03-2018 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SUPERFAMILY SSF51294 308 436 2.55E-13 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 SUPERFAMILY SSF51294 576 643 2.55E-13 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Gene3D G3DSA:3.40.50.300 252 322 0.043 T 28-03-2018 SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Pfam PF17191 RecG wedge domain 15 175 1.7E-8 T 28-03-2018 IPR033454 RecG, wedge domain SMD44_RS30330 d1eee7a3cba93cca61e5f791bfc7b54a 1089 Gene3D G3DSA:2.170.16.10 323 518 5.2E-15 T 28-03-2018 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 SUPERFAMILY SSF55469 290 482 4.06E-33 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 292 484 1.5E-94 T 28-03-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 Pfam PF00881 Nitroreductase family 297 465 1.3E-25 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 Gene3D G3DSA:3.30.1330.100 151 243 6.1E-26 T 28-03-2018 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 Pfam PF01996 F420-0:Gamma-glutamyl ligase 114 236 4.8E-34 T 28-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 Pfam PF01996 F420-0:Gamma-glutamyl ligase 45 101 3.3E-8 T 28-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 SUPERFAMILY SSF144010 39 244 3.92E-63 T 28-03-2018 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 Gene3D G3DSA:3.40.109.10 288 483 1.6E-32 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 Gene3D G3DSA:3.90.1660.10 69 150 9.9E-31 T 28-03-2018 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 42 485 51.078 T 28-03-2018 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD44_RS16445 46280863cf0ef88991a183e8e15301ed 485 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 38 243 5.2E-75 T 28-03-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD44_RS23030 85593a0cd1c71d019816b52300878d8f 285 SUPERFAMILY SSF55729 116 242 1.69E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS23030 85593a0cd1c71d019816b52300878d8f 285 Gene3D G3DSA:3.40.630.30 119 262 1.7E-12 T 28-03-2018 SMD44_RS22805 58dabc8fb02f9831ed87df4208a198c3 504 Gene3D G3DSA:3.20.20.70 55 474 1.7E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS22805 58dabc8fb02f9831ed87df4208a198c3 504 PIRSF PIRSF006429 5 492 2.0E-140 T 28-03-2018 IPR024188 Glutamate synthase large subunit-like protein SMD44_RS22805 58dabc8fb02f9831ed87df4208a198c3 504 SUPERFAMILY SSF51395 10 476 1.31E-114 T 28-03-2018 SMD44_RS22805 58dabc8fb02f9831ed87df4208a198c3 504 Pfam PF01645 Conserved region in glutamate synthase 138 454 7.2E-75 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 SMD44_RS03840 9cc4ccaddb09109812941500096f2aa4 181 Pfam PF10517 Electron transfer DM13 74 177 7.0E-29 T 28-03-2018 IPR019545 DM13 domain SMD44_RS12270 1d99cb639a33fe49dd109c19037fa3e8 290 SUPERFAMILY SSF54637 14 163 1.84E-35 T 28-03-2018 IPR029069 HotDog domain SMD44_RS12270 1d99cb639a33fe49dd109c19037fa3e8 290 Pfam PF01575 MaoC like domain 168 275 2.8E-29 T 28-03-2018 IPR002539 MaoC-like domain SMD44_RS12270 1d99cb639a33fe49dd109c19037fa3e8 290 Gene3D G3DSA:3.10.129.10 167 288 4.6E-24 T 28-03-2018 SMD44_RS12270 1d99cb639a33fe49dd109c19037fa3e8 290 Pfam PF13452 N-terminal half of MaoC dehydratase 16 138 2.3E-13 T 28-03-2018 SMD44_RS12270 1d99cb639a33fe49dd109c19037fa3e8 290 SUPERFAMILY SSF54637 174 285 4.81E-28 T 28-03-2018 IPR029069 HotDog domain SMD44_RS12270 1d99cb639a33fe49dd109c19037fa3e8 290 Gene3D G3DSA:3.10.129.10 12 166 1.0E-40 T 28-03-2018 SMD44_RS02420 5a7bd94f52079cba128088507ba5c453 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 141 1.7E-6 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS02420 5a7bd94f52079cba128088507ba5c453 145 SUPERFAMILY SSF55961 4 141 9.68E-17 T 28-03-2018 SMD44_RS02420 5a7bd94f52079cba128088507ba5c453 145 Gene3D G3DSA:3.30.530.20 3 144 4.5E-15 T 28-03-2018 IPR023393 START-like domain SMD44_RS08145 bfd754fd0b78bf15056697f1dd2284c7 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 269 1.2E-118 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 SMD44_RS08145 bfd754fd0b78bf15056697f1dd2284c7 281 SUPERFAMILY SSF56235 21 262 1.69E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS08145 bfd754fd0b78bf15056697f1dd2284c7 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 275 50.421 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 SMD44_RS08145 bfd754fd0b78bf15056697f1dd2284c7 281 Gene3D G3DSA:3.60.20.10 49 274 1.8E-48 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS08145 bfd754fd0b78bf15056697f1dd2284c7 281 PRINTS PR00141 Proteasome component signature 61 76 5.8E-7 T 28-03-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMD44_RS08145 bfd754fd0b78bf15056697f1dd2284c7 281 PRINTS PR00141 Proteasome component signature 199 210 5.8E-7 T 28-03-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMD44_RS08145 bfd754fd0b78bf15056697f1dd2284c7 281 PRINTS PR00141 Proteasome component signature 188 199 5.8E-7 T 28-03-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMD44_RS08145 bfd754fd0b78bf15056697f1dd2284c7 281 Pfam PF00227 Proteasome subunit 52 231 1.7E-37 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMD44_RS16230 b92c06215fa8a23e1417c241a99aa73b 308 Pfam PF00535 Glycosyl transferase family 2 32 196 6.4E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS16230 b92c06215fa8a23e1417c241a99aa73b 308 Gene3D G3DSA:3.90.550.10 20 272 1.0E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16230 b92c06215fa8a23e1417c241a99aa73b 308 SUPERFAMILY SSF53448 30 252 1.78E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 17 2.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 2.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 Gene3D G3DSA:3.40.50.720 1 245 2.7E-66 T 28-03-2018 SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 SUPERFAMILY SSF51735 1 242 9.34E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS22115 334b665fb0bf83ce4bc820f61eca6e38 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 241 1.0E-57 T 28-03-2018 SMD44_RS34955 46b18c3495785483dda75927eeada361 539 SUPERFAMILY SSF53822 98 427 1.45E-15 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS34955 46b18c3495785483dda75927eeada361 539 Gene3D G3DSA:3.40.50.2300 235 430 3.4E-5 T 28-03-2018 SMD44_RS34955 46b18c3495785483dda75927eeada361 539 Gene3D G3DSA:3.40.50.2300 94 234 8.7E-5 T 28-03-2018 SMD44_RS34955 46b18c3495785483dda75927eeada361 539 Pfam PF13458 Periplasmic binding protein 109 323 1.6E-8 T 28-03-2018 IPR028081 Leucine-binding protein domain SMD44_RS10140 8d37741a9d33891ee1796e5bf8fa1e66 374 Pfam PF01933 Uncharacterised protein family UPF0052 59 324 6.2E-72 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 SMD44_RS10140 8d37741a9d33891ee1796e5bf8fa1e66 374 Gene3D G3DSA:3.40.50.10680 140 368 1.3E-50 T 28-03-2018 SMD44_RS10140 8d37741a9d33891ee1796e5bf8fa1e66 374 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 59 325 1.9E-83 T 28-03-2018 IPR010119 Gluconeogenesis factor SMD44_RS10140 8d37741a9d33891ee1796e5bf8fa1e66 374 SUPERFAMILY SSF142338 56 360 2.22E-83 T 28-03-2018 SMD44_RS10140 8d37741a9d33891ee1796e5bf8fa1e66 374 Hamap MF_00973 Gluconeogenesis factor. 55 366 32.668 T 28-03-2018 IPR010119 Gluconeogenesis factor SMD44_RS05985 1a92f2d9f60859094f0a998e453fb6aa 617 SUPERFAMILY SSF51703 10 536 7.06E-153 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05985 1a92f2d9f60859094f0a998e453fb6aa 617 Pfam PF01642 Methylmalonyl-CoA mutase 53 528 1.1E-130 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05985 1a92f2d9f60859094f0a998e453fb6aa 617 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 360 385 - T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05985 1a92f2d9f60859094f0a998e453fb6aa 617 Gene3D G3DSA:3.40.50.280 486 617 2.0E-31 T 28-03-2018 SMD44_RS05985 1a92f2d9f60859094f0a998e453fb6aa 617 Gene3D G3DSA:3.20.20.240 48 481 6.5E-151 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05985 1a92f2d9f60859094f0a998e453fb6aa 617 TIGRFAM TIGR00642 mmCoA_mut_beta: methylmalonyl-CoA mutase, small subunit 9 616 1.3E-189 T 28-03-2018 IPR004608 Methylmalonyl-CoA mutase, beta chain GO:0004494|GO:0019652|GO:0031419 KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 SMD44_RS05985 1a92f2d9f60859094f0a998e453fb6aa 617 Gene3D G3DSA:1.10.196.20 9 46 2.2E-17 T 28-03-2018 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 SMART SM00345 5 64 1.6E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 SMART SM00895 93 216 1.0E-22 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 Gene3D G3DSA:1.20.120.530 88 227 1.4E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 Gene3D G3DSA:1.10.10.10 2 66 7.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 64 2.4E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 SUPERFAMILY SSF48008 91 220 1.7E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 Pfam PF07729 FCD domain 93 215 3.4E-26 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 SUPERFAMILY SSF46785 4 77 1.65E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 3.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS13635 ce97995efee51bcd81c8947fcdb01e70 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 3.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS04520 ead09e5da15d188ea0cdafb4a54c6c11 211 Gene3D G3DSA:1.10.260.40 14 58 0.0011 T 28-03-2018 SMD44_RS04520 ead09e5da15d188ea0cdafb4a54c6c11 211 Gene3D G3DSA:3.90.79.10 59 203 1.4E-22 T 28-03-2018 SMD44_RS04520 ead09e5da15d188ea0cdafb4a54c6c11 211 SUPERFAMILY SSF55811 86 207 2.3E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS04520 ead09e5da15d188ea0cdafb4a54c6c11 211 Pfam PF00293 NUDIX domain 87 190 3.2E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 Gene3D G3DSA:1.20.120.530 104 248 1.3E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 Pfam PF07729 FCD domain 118 236 7.9E-17 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 66 82 5.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 66 5.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 SMART SM00345 33 94 3.8E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 Gene3D G3DSA:1.10.10.10 4 96 7.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 SMART SM00895 117 238 1.1E-16 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 SUPERFAMILY SSF46785 25 98 9.43E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 94 1.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS07985 5c4916a139e47d7b67a21a0980f356c3 248 SUPERFAMILY SSF48008 114 246 2.62E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS23765 43e7338f5eaa3e6234a4f6ab925a5210 321 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 46 314 3.0E-49 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD44_RS23765 43e7338f5eaa3e6234a4f6ab925a5210 321 Gene3D G3DSA:3.40.190.10 39 167 9.0E-19 T 28-03-2018 SMD44_RS23765 43e7338f5eaa3e6234a4f6ab925a5210 321 SUPERFAMILY SSF53850 46 319 4.61E-42 T 28-03-2018 SMD44_RS23765 43e7338f5eaa3e6234a4f6ab925a5210 321 Gene3D G3DSA:3.40.190.120 168 257 7.5E-27 T 28-03-2018 SMD44_RS36180 760d298592370bc5e60dfe632e6a15f9 916 SUPERFAMILY SSF52009 805 912 5.23E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS36180 760d298592370bc5e60dfe632e6a15f9 916 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 41 328 1.2E-69 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD44_RS36180 760d298592370bc5e60dfe632e6a15f9 916 SUPERFAMILY SSF56059 27 379 3.06E-78 T 28-03-2018 SMD44_RS36180 760d298592370bc5e60dfe632e6a15f9 916 Gene3D G3DSA:3.30.470.20 195 340 2.3E-36 T 28-03-2018 SMD44_RS36180 760d298592370bc5e60dfe632e6a15f9 916 Pfam PF00391 PEP-utilising enzyme, mobile domain 838 909 2.0E-20 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS36180 760d298592370bc5e60dfe632e6a15f9 916 Gene3D G3DSA:3.50.30.10 811 915 1.3E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS36180 760d298592370bc5e60dfe632e6a15f9 916 Gene3D G3DSA:3.30.1490.20 24 194 1.9E-43 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS36960 cd61cbe202dc9ba9a8f3f3be49373f03 716 SUPERFAMILY SSF82866 466 676 1.1E-31 T 28-03-2018 SMD44_RS36960 cd61cbe202dc9ba9a8f3f3be49373f03 716 Pfam PF03176 MMPL family 29 352 6.0E-62 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS36960 cd61cbe202dc9ba9a8f3f3be49373f03 716 Pfam PF03176 MMPL family 384 681 9.7E-59 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS36960 cd61cbe202dc9ba9a8f3f3be49373f03 716 SUPERFAMILY SSF82866 105 327 1.07E-32 T 28-03-2018 SMD44_RS36960 cd61cbe202dc9ba9a8f3f3be49373f03 716 Gene3D G3DSA:1.20.1640.10 454 678 2.4E-31 T 28-03-2018 SMD44_RS36960 cd61cbe202dc9ba9a8f3f3be49373f03 716 Gene3D G3DSA:1.20.1640.10 112 333 3.6E-33 T 28-03-2018 SMD44_RS20900 2f35fac7f79ed6e7e4dbf8f7bb8562a3 160 Gene3D G3DSA:3.90.79.10 1 127 5.8E-17 T 28-03-2018 SMD44_RS20900 2f35fac7f79ed6e7e4dbf8f7bb8562a3 160 Pfam PF00293 NUDIX domain 9 113 1.2E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS20900 2f35fac7f79ed6e7e4dbf8f7bb8562a3 160 SUPERFAMILY SSF55811 2 113 5.96E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Gene3D G3DSA:3.30.56.10 158 193 3.8E-8 T 28-03-2018 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Gene3D G3DSA:2.40.50.140 33 157 1.4E-41 T 28-03-2018 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SUPERFAMILY SSF56037 206 418 6.28E-64 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Gene3D G3DSA:3.30.56.10 425 493 2.9E-19 T 28-03-2018 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Gene3D G3DSA:3.30.930.10 508 755 5.6E-41 T 28-03-2018 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SUPERFAMILY SSF54991 765 861 1.29E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Pfam PF03484 tRNA synthetase B5 domain 429 493 1.8E-16 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Pfam PF03147 Ferredoxin-fold anticodon binding domain 768 861 2.2E-22 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 855 39.729 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SUPERFAMILY SSF55681 489 605 6.46E-42 T 28-03-2018 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SUPERFAMILY SSF55681 640 755 6.46E-42 T 28-03-2018 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SUPERFAMILY SSF50249 45 205 2.2E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Gene3D G3DSA:3.30.70.380 765 861 3.9E-23 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Gene3D G3DSA:3.50.40.10 206 421 2.7E-83 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SMART SM00873 221 410 1.1E-80 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SMART SM00896 768 861 8.7E-39 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SUPERFAMILY SSF46955 426 497 1.01E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Pfam PF03483 B3/4 domain 221 410 2.5E-67 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 861 9.1E-182 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 SMART SM00874 426 493 1.4E-20 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMD44_RS07895 11c49821bcf9f186e4357a90ddcfb104 863 Pfam PF01588 Putative tRNA binding domain 48 154 2.6E-20 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 Gene3D G3DSA:1.10.630.10 10 419 1.7E-87 T 28-03-2018 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 SUPERFAMILY SSF48264 14 419 1.26E-104 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 166 181 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 366 377 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 336 351 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 149 165 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 357 366 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 290 301 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 308 335 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 204 226 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 PRINTS PR00359 B-class P450 signature 99 110 1.3E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS16805 30c6eced8fe8a3c2999c8a5ba5c8fa08 422 Pfam PF00067 Cytochrome P450 199 386 1.4E-22 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS12560 2d41a4ab35c15531100f1c04788514b9 206 PIRSF PIRSF006324 1 206 5.1E-44 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMD44_RS12560 2d41a4ab35c15531100f1c04788514b9 206 Pfam PF01810 LysE type translocator 14 203 4.8E-31 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMD44_RS07870 4b47763b1336cf82fe4f71225e0c93c2 286 SUPERFAMILY SSF51735 2 186 5.98E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS07870 4b47763b1336cf82fe4f71225e0c93c2 286 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 3.5E-33 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS07870 4b47763b1336cf82fe4f71225e0c93c2 286 SUPERFAMILY SSF48179 189 285 2.47E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS07870 4b47763b1336cf82fe4f71225e0c93c2 286 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 186 3.7E-60 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS07870 4b47763b1336cf82fe4f71225e0c93c2 286 Gene3D G3DSA:1.10.1040.10 188 286 1.5E-32 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS07870 4b47763b1336cf82fe4f71225e0c93c2 286 Gene3D G3DSA:3.40.50.720 2 187 2.5E-48 T 28-03-2018 SMD44_RS07870 4b47763b1336cf82fe4f71225e0c93c2 286 PIRSF PIRSF000105 2 286 3.4E-78 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMD44_RS15705 73979e1acc8b85ab7b8417757bdbb31e 194 Gene3D G3DSA:3.40.50.850 1 190 1.8E-61 T 28-03-2018 SMD44_RS15705 73979e1acc8b85ab7b8417757bdbb31e 194 Pfam PF00857 Isochorismatase family 4 189 4.4E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS15705 73979e1acc8b85ab7b8417757bdbb31e 194 SUPERFAMILY SSF52499 2 189 4.19E-52 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS04030 0a59e9c20e0ad2c49102c6cab60420bf 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04030 0a59e9c20e0ad2c49102c6cab60420bf 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04030 0a59e9c20e0ad2c49102c6cab60420bf 191 Gene3D G3DSA:1.10.357.10 60 190 9.6E-18 T 28-03-2018 SMD44_RS04030 0a59e9c20e0ad2c49102c6cab60420bf 191 SUPERFAMILY SSF46689 7 83 2.05E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS04030 0a59e9c20e0ad2c49102c6cab60420bf 191 Gene3D G3DSA:1.10.10.60 6 59 7.9E-15 T 28-03-2018 SMD44_RS04030 0a59e9c20e0ad2c49102c6cab60420bf 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 6.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS04030 0a59e9c20e0ad2c49102c6cab60420bf 191 SUPERFAMILY SSF48498 87 187 2.12E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 Pfam PF00318 Ribosomal protein S2 9 225 2.4E-95 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 1.1E-106 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 Gene3D G3DSA:3.40.50.10490 5 294 6.1E-97 T 28-03-2018 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 PRINTS PR00395 Ribosomal protein S2 signature 159 176 7.9E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 PRINTS PR00395 Ribosomal protein S2 signature 87 104 7.9E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 PRINTS PR00395 Ribosomal protein S2 signature 6 24 7.9E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 PRINTS PR00395 Ribosomal protein S2 signature 176 187 7.9E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 PRINTS PR00395 Ribosomal protein S2 signature 37 46 7.9E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 PRINTS PR00395 Ribosomal protein S2 signature 197 211 7.9E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 42.091 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30565 a9a18e8b8dec492b33fa307315e9022a 305 SUPERFAMILY SSF52313 6 230 1.57E-90 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain SMD44_RS34230 07e5a6937e58a302c3fd86a9b2e4076c 535 SUPERFAMILY SSF53474 323 467 4.09E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS34230 07e5a6937e58a302c3fd86a9b2e4076c 535 SUPERFAMILY SSF53474 175 239 4.09E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS34230 07e5a6937e58a302c3fd86a9b2e4076c 535 SUPERFAMILY SSF53474 85 136 4.09E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS34230 07e5a6937e58a302c3fd86a9b2e4076c 535 Gene3D G3DSA:3.40.50.1820 25 484 3.6E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS34230 07e5a6937e58a302c3fd86a9b2e4076c 535 Pfam PF00561 alpha/beta hydrolase fold 91 461 1.9E-39 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 333 8.7E-126 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 SUPERFAMILY SSF51735 2 149 3.64E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 SMART SM00859 2 113 2.8E-35 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 333 31.954 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 132 319 1.0E-48 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 Gene3D G3DSA:3.40.50.720 1 132 1.8E-31 T 28-03-2018 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 111 2.3E-27 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 236 250 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 PIRSF PIRSF000148 1 337 4.6E-103 T 28-03-2018 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 Gene3D G3DSA:3.30.360.10 133 316 1.3E-63 T 28-03-2018 SMD44_RS14315 97909cf628c30da26394384e9e4e2dfb 339 SUPERFAMILY SSF55347 122 320 1.28E-58 T 28-03-2018 SMD44_RS09465 c5775f17c20c5c97bf20c955f723e251 438 Gene3D G3DSA:3.20.20.140 14 386 3.0E-55 T 28-03-2018 SMD44_RS09465 c5775f17c20c5c97bf20c955f723e251 438 Pfam PF04909 Amidohydrolase 24 383 1.1E-22 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS09465 c5775f17c20c5c97bf20c955f723e251 438 SUPERFAMILY SSF51556 18 47 4.16E-56 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS09465 c5775f17c20c5c97bf20c955f723e251 438 SUPERFAMILY SSF51556 78 384 4.16E-56 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS12675 17470ab72ccf410b8ac4eb527a4cbb9f 248 Gene3D G3DSA:2.60.60.30 41 230 3.3E-29 T 28-03-2018 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 Gene3D G3DSA:3.40.50.300 21 178 2.9E-17 T 28-03-2018 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 Gene3D G3DSA:1.10.150.200 459 527 3.2E-7 T 28-03-2018 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 Gene3D G3DSA:1.10.150.200 528 571 3.9E-6 T 28-03-2018 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 SUPERFAMILY SSF48452 471 647 2.09E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 SMART SM00382 59 218 0.0017 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 Gene3D G3DSA:1.25.40.10 572 672 2.9E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 SUPERFAMILY SSF52540 28 284 2.04E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 PRINTS PR00364 Disease resistance protein signature 62 77 3.4E-7 T 28-03-2018 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 PRINTS PR00364 Disease resistance protein signature 226 240 3.4E-7 T 28-03-2018 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 PRINTS PR00364 Disease resistance protein signature 138 152 3.4E-7 T 28-03-2018 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 Pfam PF00931 NB-ARC domain 51 245 3.0E-10 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 Pfam PF13424 Tetratricopeptide repeat 560 632 3.4E-7 T 28-03-2018 SMD44_RS09120 ff07330f55975542f5a716f4205af7b6 709 Pfam PF13424 Tetratricopeptide repeat 480 551 3.2E-9 T 28-03-2018 SMD44_RS32180 19fc43a4b285235895c7e6341e493666 132 Gene3D G3DSA:3.30.1330.40 4 132 2.6E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS32180 19fc43a4b285235895c7e6341e493666 132 Pfam PF01042 Endoribonuclease L-PSP 12 131 3.5E-17 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS32180 19fc43a4b285235895c7e6341e493666 132 SUPERFAMILY SSF55298 11 132 2.36E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS19190 aeb8d4fca8b8178d0063f9ee073b5ea6 262 PIRSF PIRSF006648 1 262 1.5E-62 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS19190 aeb8d4fca8b8178d0063f9ee073b5ea6 262 Pfam PF01061 ABC-2 type transporter 19 226 1.1E-21 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 Gene3D G3DSA:3.30.565.10 256 409 8.7E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 SMART SM00304 126 179 4.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 296 404 6.0E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 SUPERFAMILY SSF55874 253 404 1.7E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 Gene3D G3DSA:1.10.287.130 170 242 2.4E-9 T 28-03-2018 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 SMART SM00387 296 406 2.9E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 SUPERFAMILY SSF47384 163 245 5.1E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 SMART SM00388 180 246 9.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 Pfam PF00672 HAMP domain 127 176 9.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 383 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 358 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 344 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 403 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 SUPERFAMILY SSF158472 127 177 1.83E-6 T 28-03-2018 SMD44_RS18225 03e955936770660a9a1ddae187c932ae 418 Pfam PF00512 His Kinase A (phospho-acceptor) domain 181 245 2.9E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS05795 b2c11806a6d359f26f4128e8b7077961 219 PIRSF PIRSF006324 2 216 4.8E-45 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMD44_RS05795 b2c11806a6d359f26f4128e8b7077961 219 Pfam PF01810 LysE type translocator 15 214 3.2E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMD44_RS00850 ee1fda639af9304a5b277f7ac4572cae 397 Gene3D G3DSA:3.40.710.10 38 397 1.9E-70 T 28-03-2018 SMD44_RS00850 ee1fda639af9304a5b277f7ac4572cae 397 SUPERFAMILY SSF56601 57 378 1.76E-67 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS00850 ee1fda639af9304a5b277f7ac4572cae 397 Pfam PF00144 Beta-lactamase 65 374 3.2E-56 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS15070 5ed3c8198af168a0c36a998dbd43bdf5 488 Gene3D G3DSA:2.60.40.290 32 137 5.7E-30 T 28-03-2018 SMD44_RS15070 5ed3c8198af168a0c36a998dbd43bdf5 488 SMART SM00637 40 137 7.1E-32 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD44_RS15070 5ed3c8198af168a0c36a998dbd43bdf5 488 Pfam PF00553 Cellulose binding domain 42 137 7.2E-22 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD44_RS15070 5ed3c8198af168a0c36a998dbd43bdf5 488 Pfam PF04886 PT repeat 146 181 8.9E-7 T 28-03-2018 IPR006970 PT repeat SMD44_RS15070 5ed3c8198af168a0c36a998dbd43bdf5 488 SUPERFAMILY SSF51445 211 459 2.11E-20 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS15070 5ed3c8198af168a0c36a998dbd43bdf5 488 SUPERFAMILY SSF49384 37 138 1.26E-27 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 SMD44_RS15070 5ed3c8198af168a0c36a998dbd43bdf5 488 Gene3D G3DSA:3.20.20.80 193 477 1.3E-27 T 28-03-2018 SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 Pfam PF13234 rRNA-processing arch domain 496 597 7.7E-6 T 28-03-2018 IPR025696 rRNA-processing arch domain SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 SUPERFAMILY SSF52540 360 453 9.15E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 SUPERFAMILY SSF52540 46 187 9.15E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 SUPERFAMILY SSF52540 262 318 9.15E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 SMART SM00487 32 217 9.6E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 SMART SM01142 757 935 3.7E-60 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 Pfam PF08148 DSHCT (NUC185) domain 760 930 3.1E-36 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 Gene3D G3DSA:3.40.50.300 6 208 1.0E-38 T 28-03-2018 SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 Pfam PF00270 DEAD/DEAH box helicase 38 185 1.7E-20 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 SMART SM00490 351 440 5.0E-13 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 Pfam PF00271 Helicase conserved C-terminal domain 361 440 2.0E-4 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS08075 322fcfb068faf57c49815cf3708a8a41 936 Gene3D G3DSA:3.40.50.300 281 576 1.8E-16 T 28-03-2018 SMD44_RS34760 8a4cc44ccbcd0009c9d424ab7ceae82e 313 Pfam PF01261 Xylose isomerase-like TIM barrel 39 250 1.4E-32 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS34760 8a4cc44ccbcd0009c9d424ab7ceae82e 313 Gene3D G3DSA:3.20.20.150 14 299 9.8E-60 T 28-03-2018 SMD44_RS34760 8a4cc44ccbcd0009c9d424ab7ceae82e 313 SUPERFAMILY SSF51658 15 295 2.09E-59 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS36770 ba02e6c87aaca602f871aa0c0dfa2635 325 SMART SM00382 31 214 4.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS36770 ba02e6c87aaca602f871aa0c0dfa2635 325 Gene3D G3DSA:3.40.50.300 1 265 1.3E-70 T 28-03-2018 SMD44_RS36770 ba02e6c87aaca602f871aa0c0dfa2635 325 Pfam PF00005 ABC transporter 23 165 6.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS36770 ba02e6c87aaca602f871aa0c0dfa2635 325 SUPERFAMILY SSF52540 5 224 6.71E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS01450 dd9e827853aa6598a295dd5708af22cc 514 SUPERFAMILY SSF53474 15 503 5.66E-108 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01450 dd9e827853aa6598a295dd5708af22cc 514 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 183 198 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site SMD44_RS01450 dd9e827853aa6598a295dd5708af22cc 514 PRINTS PR00878 Cholinesterase signature 115 144 4.9E-5 T 28-03-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 SMD44_RS01450 dd9e827853aa6598a295dd5708af22cc 514 PRINTS PR00878 Cholinesterase signature 420 432 4.9E-5 T 28-03-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 SMD44_RS01450 dd9e827853aa6598a295dd5708af22cc 514 Pfam PF00135 Carboxylesterase family 14 487 6.6E-93 T 28-03-2018 IPR002018 Carboxylesterase, type B SMD44_RS01450 dd9e827853aa6598a295dd5708af22cc 514 Gene3D G3DSA:3.40.50.1820 10 505 1.7E-121 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS43545 a2082a1c8832df90a9b372e1aa66d20a 147 SUPERFAMILY SSF52540 14 92 4.25E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43545 a2082a1c8832df90a9b372e1aa66d20a 147 Pfam PF03796 DnaB-like helicase C terminal domain 18 117 2.3E-13 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 SMD44_RS43545 a2082a1c8832df90a9b372e1aa66d20a 147 Gene3D G3DSA:3.40.50.300 17 127 2.4E-12 T 28-03-2018 SMD44_RS07095 cc10ebb356fb65ac711abc499bb90520 497 PIRSF PIRSF006060 32 495 4.8E-95 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS07095 cc10ebb356fb65ac711abc499bb90520 497 Pfam PF13520 Amino acid permease 49 466 2.3E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS07095 cc10ebb356fb65ac711abc499bb90520 497 TIGRFAM TIGR00909 2A0306: amino acid transporter 45 477 1.7E-173 T 28-03-2018 IPR004758 Amino acid transporter SMD44_RS39550 d25c0433050da8c6a9cbf218c7bbf930 682 Gene3D G3DSA:3.50.50.60 25 256 5.3E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS39550 d25c0433050da8c6a9cbf218c7bbf930 682 SUPERFAMILY SSF51905 90 136 4.66E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS39550 d25c0433050da8c6a9cbf218c7bbf930 682 SUPERFAMILY SSF51905 181 307 4.66E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS39550 d25c0433050da8c6a9cbf218c7bbf930 682 Pfam PF13454 FAD-NAD(P)-binding 92 256 2.0E-36 T 28-03-2018 SMD44_RS34500 e7c6ee8b33a2329adcfc26d80ddeddaf 295 Gene3D G3DSA:1.10.260.40 30 117 3.7E-14 T 28-03-2018 SMD44_RS34500 e7c6ee8b33a2329adcfc26d80ddeddaf 295 SUPERFAMILY SSF47413 39 97 7.04E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS34500 e7c6ee8b33a2329adcfc26d80ddeddaf 295 SMART SM00530 43 98 1.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS34500 e7c6ee8b33a2329adcfc26d80ddeddaf 295 Pfam PF13560 Helix-turn-helix domain 40 101 9.8E-13 T 28-03-2018 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 282 300 1.0E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 466 483 1.0E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 160 181 1.0E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 87 107 1.0E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 231 248 1.0E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 304 317 1.0E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 448 464 1.0E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 SUPERFAMILY SSF55545 5 136 1.23E-23 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 5 134 1.3E-22 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 PIRSF PIRSF001093 69 527 1.6E-74 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 Gene3D G3DSA:3.20.20.80 135 527 1.4E-139 T 28-03-2018 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 137 483 3.2E-122 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 SUPERFAMILY SSF51445 137 500 1.66E-116 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS15900 d6c741081d73391ff5d71a680bc437a8 541 Gene3D G3DSA:3.30.379.10 1 134 1.4E-28 T 28-03-2018 SMD44_RS37800 a62ea814a5364f9792131b2cf5b5dbfb 245 Gene3D G3DSA:3.40.50.1000 9 56 4.3E-4 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS37800 a62ea814a5364f9792131b2cf5b5dbfb 245 Gene3D G3DSA:3.40.50.1000 96 238 4.4E-28 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS37800 a62ea814a5364f9792131b2cf5b5dbfb 245 Pfam PF13419 Haloacid dehalogenase-like hydrolase 31 206 1.3E-25 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS37800 a62ea814a5364f9792131b2cf5b5dbfb 245 Gene3D G3DSA:1.10.150.240 57 95 1.9E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS37800 a62ea814a5364f9792131b2cf5b5dbfb 245 SUPERFAMILY SSF56784 29 237 6.92E-46 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS37800 a62ea814a5364f9792131b2cf5b5dbfb 245 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 113 202 3.6E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS37800 a62ea814a5364f9792131b2cf5b5dbfb 245 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 105 203 3.4E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS14190 75a37f7646aaad84a5b4925cae6129ed 792 Pfam PF02687 FtsX-like permease family 259 354 5.1E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS14190 75a37f7646aaad84a5b4925cae6129ed 792 Pfam PF02687 FtsX-like permease family 703 788 5.6E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS02760 65df4c71722e42de1a203ae1e0b14709 250 SUPERFAMILY SSF46785 28 98 2.44E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02760 65df4c71722e42de1a203ae1e0b14709 250 Pfam PF07729 FCD domain 104 232 6.3E-25 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS02760 65df4c71722e42de1a203ae1e0b14709 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 94 1.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS02760 65df4c71722e42de1a203ae1e0b14709 250 Gene3D G3DSA:1.10.10.10 12 89 9.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02760 65df4c71722e42de1a203ae1e0b14709 250 SMART SM00895 104 233 3.8E-15 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS02760 65df4c71722e42de1a203ae1e0b14709 250 Gene3D G3DSA:1.20.120.530 90 247 9.2E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS02760 65df4c71722e42de1a203ae1e0b14709 250 SUPERFAMILY SSF48008 103 239 1.26E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS02760 65df4c71722e42de1a203ae1e0b14709 250 SMART SM00345 36 94 5.8E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS25115 b604de02560dee29e5d132587ab77643 143 Pfam PF12802 MarR family 31 91 3.4E-11 T 28-03-2018 SMD44_RS25115 b604de02560dee29e5d132587ab77643 143 SMART SM00347 26 127 2.7E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS25115 b604de02560dee29e5d132587ab77643 143 SUPERFAMILY SSF46785 15 140 2.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25115 b604de02560dee29e5d132587ab77643 143 Gene3D G3DSA:1.10.10.10 7 143 6.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 Gene3D G3DSA:3.40.220.10 1 185 8.2E-49 T 28-03-2018 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 SUPERFAMILY SSF53187 195 511 1.97E-112 T 28-03-2018 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 144 1.0E-26 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 Gene3D G3DSA:3.40.630.10 186 518 4.1E-132 T 28-03-2018 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 SUPERFAMILY SSF52949 17 151 1.47E-25 T 28-03-2018 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 361 368 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 201 507 2.9E-118 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 PRINTS PR00481 Cytosol aminopeptidase signature 276 293 1.6E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 PRINTS PR00481 Cytosol aminopeptidase signature 385 400 1.6E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 PRINTS PR00481 Cytosol aminopeptidase signature 298 319 1.6E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 PRINTS PR00481 Cytosol aminopeptidase signature 335 356 1.6E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 PRINTS PR00481 Cytosol aminopeptidase signature 357 377 1.6E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD44_RS11520 6e01199bb75d09c6580b1d62b9461173 519 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 515 34.289 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 SMD44_RS25175 3bacd43db54ee4f4deb7c19f70cdb0c3 210 Gene3D G3DSA:3.40.630.30 15 210 1.1E-35 T 28-03-2018 SMD44_RS25175 3bacd43db54ee4f4deb7c19f70cdb0c3 210 Pfam PF00583 Acetyltransferase (GNAT) family 126 186 2.8E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS25175 3bacd43db54ee4f4deb7c19f70cdb0c3 210 SUPERFAMILY SSF55729 20 206 4.96E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 Pfam PF07729 FCD domain 95 220 1.0E-29 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 Gene3D G3DSA:1.20.120.530 77 233 6.9E-35 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 SMART SM00895 95 221 4.5E-26 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 SUPERFAMILY SSF48008 92 227 4.45E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 Gene3D G3DSA:1.10.10.10 3 76 3.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 74 5.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 SUPERFAMILY SSF46785 6 78 2.08E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 7.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 7.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS05000 f33754f12036b6e6b5ba2b1f72431417 233 SMART SM00345 15 74 4.5E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15225 a7670a92c31c6c477c0a30637fb9056a 242 Pfam PF00975 Thioesterase domain 16 229 3.5E-48 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS15225 a7670a92c31c6c477c0a30637fb9056a 242 SUPERFAMILY SSF53474 14 240 1.93E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS15225 a7670a92c31c6c477c0a30637fb9056a 242 Gene3D G3DSA:3.40.50.1820 2 241 1.0E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS15875 3dd8d370f502232cf37ee89d7c897db8 228 Gene3D G3DSA:2.40.440.10 106 219 6.7E-11 T 28-03-2018 SMD44_RS15875 3dd8d370f502232cf37ee89d7c897db8 228 SUPERFAMILY SSF141523 118 219 1.96E-7 T 28-03-2018 SMD44_RS32655 7ba79f699c039aed8649cf010ce7713f 333 SUPERFAMILY SSF51430 1 312 8.51E-106 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS32655 7ba79f699c039aed8649cf010ce7713f 333 Gene3D G3DSA:3.20.20.100 1 318 9.0E-99 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS32655 7ba79f699c039aed8649cf010ce7713f 333 Pfam PF00248 Aldo/keto reductase family 15 311 7.7E-78 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS35955 c5fc8c00dd660c5b30517a2af8f4ad20 397 SUPERFAMILY SSF51735 4 151 2.23E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35955 c5fc8c00dd660c5b30517a2af8f4ad20 397 Gene3D G3DSA:3.30.360.10 143 386 1.8E-37 T 28-03-2018 SMD44_RS35955 c5fc8c00dd660c5b30517a2af8f4ad20 397 Gene3D G3DSA:3.40.50.720 1 142 9.8E-37 T 28-03-2018 SMD44_RS35955 c5fc8c00dd660c5b30517a2af8f4ad20 397 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 123 1.3E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS35955 c5fc8c00dd660c5b30517a2af8f4ad20 397 SUPERFAMILY SSF55347 129 212 4.14E-24 T 28-03-2018 SMD44_RS35955 c5fc8c00dd660c5b30517a2af8f4ad20 397 SUPERFAMILY SSF55347 240 314 4.14E-24 T 28-03-2018 SMD44_RS35955 c5fc8c00dd660c5b30517a2af8f4ad20 397 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 214 9.5E-12 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 Pfam PF00072 Response regulator receiver domain 4 114 1.4E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 Gene3D G3DSA:1.10.10.10 134 214 2.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 SMART SM00421 152 209 1.6E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 Gene3D G3DSA:3.40.50.2300 1 133 3.6E-35 T 28-03-2018 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 SUPERFAMILY SSF52172 2 134 8.97E-32 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 8.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 8.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 8.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 SUPERFAMILY SSF46894 138 215 1.56E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23955 16c693f0adffa245032b926f6fed2068 226 SMART SM00448 2 115 7.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 Pfam PF00732 GMC oxidoreductase 7 292 1.2E-57 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 SUPERFAMILY SSF54373 286 450 3.63E-38 T 28-03-2018 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 SUPERFAMILY SSF51905 449 509 2.47E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 SUPERFAMILY SSF51905 4 284 2.47E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 Gene3D G3DSA:3.30.560.10 107 465 3.3E-82 T 28-03-2018 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 250 264 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 Gene3D G3DSA:4.10.450.10 41 106 3.9E-14 T 28-03-2018 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 PIRSF PIRSF000137 1 316 3.5E-81 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 PIRSF PIRSF000137 310 510 1.3E-43 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS26165 677d7df96972075960b6c592a6c4ec79 511 Pfam PF05199 GMC oxidoreductase 363 502 4.2E-38 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS20705 6fa7798a54a1d19a7eaf8aa4d6b35def 231 Gene3D G3DSA:3.40.30.10 50 231 3.2E-22 T 28-03-2018 SMD44_RS20705 6fa7798a54a1d19a7eaf8aa4d6b35def 231 Pfam PF02630 SCO1/SenC 64 166 4.0E-20 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS20705 6fa7798a54a1d19a7eaf8aa4d6b35def 231 SUPERFAMILY SSF52833 59 228 5.08E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS17455 5867b235c6d93ee99ffe12ebd13d930c 175 Pfam PF13302 Acetyltransferase (GNAT) domain 4 140 1.1E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS17455 5867b235c6d93ee99ffe12ebd13d930c 175 SUPERFAMILY SSF55729 4 144 1.53E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS17455 5867b235c6d93ee99ffe12ebd13d930c 175 Gene3D G3DSA:3.40.630.30 3 168 2.4E-21 T 28-03-2018 SMD44_RS05505 95f54b8c4221bfe17c720c2cacacfc38 140 Gene3D G3DSA:3.30.70.1060 1 136 8.2E-37 T 28-03-2018 SMD44_RS05505 95f54b8c4221bfe17c720c2cacacfc38 140 SUPERFAMILY SSF54909 23 111 1.55E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS05505 95f54b8c4221bfe17c720c2cacacfc38 140 Pfam PF03795 YCII-related domain 1 111 1.2E-13 T 28-03-2018 IPR005545 YCII-related SMD44_RS38805 0a8b20f4c62f1fcb04af74c819511cd3 216 SUPERFAMILY SSF102588 12 210 3.14E-32 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS38805 0a8b20f4c62f1fcb04af74c819511cd3 216 Pfam PF02585 GlcNAc-PI de-N-acetylase 15 129 7.9E-12 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD44_RS38805 0a8b20f4c62f1fcb04af74c819511cd3 216 Gene3D G3DSA:3.40.50.10320 9 213 1.8E-30 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS04945 b9a4cbf384d0a1160647d7ae360778a4 204 Pfam PF17197 Domain of unknown function (DUF5134) 33 203 5.8E-36 T 28-03-2018 IPR033458 Protein of unknown function DUF5134 SMD44_RS31050 132b08b5ed6df39284b2a3a92e0e3316 150 SUPERFAMILY SSF48452 97 145 2.52E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS31050 132b08b5ed6df39284b2a3a92e0e3316 150 Gene3D G3DSA:1.25.40.10 53 149 2.8E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 SMART SM00450 6 138 1.6E-25 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 SMART SM00450 156 275 8.4E-14 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 SUPERFAMILY SSF52821 158 281 3.27E-30 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 Gene3D G3DSA:3.40.250.10 1 150 9.3E-31 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 ProSitePatterns PS00380 Rhodanese signature 1. 46 57 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 Pfam PF00581 Rhodanese-like domain 7 133 2.0E-17 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 Pfam PF00581 Rhodanese-like domain 169 271 7.3E-10 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 Gene3D G3DSA:3.40.250.10 160 284 2.0E-23 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS31675 484c29623947f9ff4f18bb0e59ec63cc 284 SUPERFAMILY SSF52821 4 145 4.58E-36 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS17700 057ba355f1168c17fb3a86721734becb 163 Pfam PF03018 Dirigent-like protein 79 147 3.3E-7 T 28-03-2018 IPR004265 Dirigent protein SMD44_RS17700 057ba355f1168c17fb3a86721734becb 163 Gene3D G3DSA:2.40.480.10 28 160 2.1E-14 T 28-03-2018 IPR034871 Allene oxide cyclase/dirigent protein GO:0016853 SMD44_RS36350 6220586fbfddf2dba396013336d4ec47 338 Gene3D G3DSA:3.30.360.10 138 338 1.8E-35 T 28-03-2018 SMD44_RS36350 6220586fbfddf2dba396013336d4ec47 338 SUPERFAMILY SSF51735 2 153 7.29E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36350 6220586fbfddf2dba396013336d4ec47 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 35 125 2.2E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS36350 6220586fbfddf2dba396013336d4ec47 338 Gene3D G3DSA:3.40.50.720 1 137 1.4E-28 T 28-03-2018 SMD44_RS36350 6220586fbfddf2dba396013336d4ec47 338 SUPERFAMILY SSF55347 130 267 2.45E-24 T 28-03-2018 SMD44_RS36350 6220586fbfddf2dba396013336d4ec47 338 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 214 3.5E-6 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS27630 b1d0faca2b2d908ef779cc6f7ea9dabc 128 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS27630 b1d0faca2b2d908ef779cc6f7ea9dabc 128 SUPERFAMILY SSF55811 4 125 2.71E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS27630 b1d0faca2b2d908ef779cc6f7ea9dabc 128 Pfam PF00293 NUDIX domain 6 109 5.1E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS27630 b1d0faca2b2d908ef779cc6f7ea9dabc 128 PRINTS PR00502 NUDIX hydrolase family signature 33 47 8.0E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS27630 b1d0faca2b2d908ef779cc6f7ea9dabc 128 PRINTS PR00502 NUDIX hydrolase family signature 47 62 8.0E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS27630 b1d0faca2b2d908ef779cc6f7ea9dabc 128 Gene3D G3DSA:3.90.79.10 1 128 1.3E-27 T 28-03-2018 SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 Gene3D G3DSA:3.30.565.10 311 475 5.0E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 SUPERFAMILY SSF47384 251 325 1.2E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 SMART SM00304 211 267 4.4E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 SMART SM00387 364 477 7.2E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 475 1.4E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 269 325 1.4E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 SUPERFAMILY SSF55874 315 475 4.19E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 SMART SM00388 268 326 1.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 Pfam PF00672 HAMP domain 212 263 1.0E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS23925 28ae593f6c092ae368a15a90486a8f31 498 Gene3D G3DSA:1.10.287.130 258 310 2.7E-11 T 28-03-2018 SMD44_RS26580 036f2b5d6ce33bd04990c4270a497951 164 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 44 147 3.4E-17 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26580 036f2b5d6ce33bd04990c4270a497951 164 Gene3D G3DSA:1.20.1300.10 30 160 1.1E-24 T 28-03-2018 SMD44_RS26580 036f2b5d6ce33bd04990c4270a497951 164 SUPERFAMILY SSF81343 43 161 6.98E-33 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 2.6E-65 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 Gene3D G3DSA:3.30.1490.20 85 177 6.8E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 411 3.8E-27 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 Gene3D G3DSA:3.30.470.20 179 316 2.7E-59 T 28-03-2018 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 413 1.1E-144 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 414 40.656 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 SMART SM01210 318 414 2.0E-44 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 3.5E-30 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 Gene3D G3DSA:3.90.600.10 318 414 5.5E-31 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 SUPERFAMILY SSF56059 102 309 4.77E-56 T 28-03-2018 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 Gene3D G3DSA:3.40.50.20 2 84 1.7E-34 T 28-03-2018 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 SMART SM01209 101 283 1.3E-112 T 28-03-2018 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 SUPERFAMILY SSF52440 2 101 1.22E-30 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD44_RS20045 632293a1512ec37371b5bc6d2b0ba0d5 419 SUPERFAMILY SSF51246 316 413 6.28E-25 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMD44_RS06925 a65e1da465a80acd97322f6037f52044 388 SUPERFAMILY SSF159245 69 267 6.41E-10 T 28-03-2018 SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 SUPERFAMILY SSF52821 255 384 1.17E-14 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 Gene3D G3DSA:3.40.250.10 387 497 5.3E-20 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 Pfam PF00753 Metallo-beta-lactamase superfamily 16 216 4.6E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 SUPERFAMILY SSF52821 378 489 2.36E-22 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 Pfam PF00581 Rhodanese-like domain 396 479 4.7E-8 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 SUPERFAMILY SSF56281 4 88 6.1E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 SUPERFAMILY SSF56281 124 274 6.1E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 SMART SM00849 13 216 3.1E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 SMART SM00450 393 488 9.2E-13 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 Gene3D G3DSA:3.40.250.10 283 386 5.1E-8 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05265 bc3c1d810284190020276e7bfec2474a 498 Gene3D G3DSA:3.60.15.10 3 276 5.5E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 593 603 6.1E-23 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 292 306 6.1E-23 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 671 683 6.1E-23 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 442 456 6.1E-23 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 571 582 6.1E-23 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 648 667 6.1E-23 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 SUPERFAMILY SSF81653 252 342 6.8E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 Pfam PF00702 haloacid dehalogenase-like hydrolase 438 662 4.0E-44 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 SUPERFAMILY SSF81665 697 724 8.11E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 SUPERFAMILY SSF81665 343 436 8.11E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 SUPERFAMILY SSF81665 211 245 8.11E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 160 750 2.0E-178 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 444 450 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 SUPERFAMILY SSF55008 3 68 1.27E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 Pfam PF00122 E1-E2 ATPase 245 420 9.2E-50 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 Pfam PF00403 Heavy-metal-associated domain 8 65 2.0E-11 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 SUPERFAMILY SSF56784 503 748 1.3E-54 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 SUPERFAMILY SSF56784 440 460 1.3E-54 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 551 729 7.6E-41 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 215 474 1.8E-41 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 PRINTS PR00940 Cation-transporting P-type ATPase A signature 245 264 2.2E-6 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 PRINTS PR00940 Cation-transporting P-type ATPase A signature 91 109 2.2E-6 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 Gene3D G3DSA:3.40.1110.10 458 573 1.3E-32 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 Gene3D G3DSA:3.30.70.100 1 71 2.6E-18 T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 38 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 ProSitePatterns PS01229 Hypothetical cof family signature 2. 648 670 - T 28-03-2018 SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 Gene3D G3DSA:3.40.50.1000 574 712 7.3E-40 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS14755 879396d17594aed27d35aaa9d55b582e 754 Gene3D G3DSA:1.20.1110.10 204 457 9.6E-46 T 28-03-2018 SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 2.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 201 2.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 2.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 SUPERFAMILY SSF51735 19 263 1.49E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 Gene3D G3DSA:3.40.50.720 5 314 4.8E-61 T 28-03-2018 SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 201 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 222 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS13435 f2af43e437943a828787219c6df1c09f 317 Pfam PF00106 short chain dehydrogenase 22 223 8.1E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS24295 a25e7e9ab963a1a5052fcee76bfe5f8e 296 Gene3D G3DSA:1.10.10.60 172 248 1.7E-8 T 28-03-2018 SMD44_RS24295 a25e7e9ab963a1a5052fcee76bfe5f8e 296 SMART SM00342 210 294 5.0E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS24295 a25e7e9ab963a1a5052fcee76bfe5f8e 296 Pfam PF12833 Helix-turn-helix domain 216 294 1.0E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS24295 a25e7e9ab963a1a5052fcee76bfe5f8e 296 Gene3D G3DSA:1.10.10.60 249 296 5.3E-8 T 28-03-2018 SMD44_RS38980 8d093f7d84b922f672c8533b5bb6c62c 253 SUPERFAMILY SSF53335 4 191 5.16E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38980 8d093f7d84b922f672c8533b5bb6c62c 253 Gene3D G3DSA:3.40.50.150 4 236 7.3E-33 T 28-03-2018 SMD44_RS38980 8d093f7d84b922f672c8533b5bb6c62c 253 Pfam PF08241 Methyltransferase domain 34 127 1.6E-16 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 Gene3D G3DSA:1.10.1610.10 1264 1331 4.3E-24 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 Gene3D G3DSA:2.160.20.50 261 343 1.4E-4 T 28-03-2018 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1274 1607 2.4E-124 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 SUPERFAMILY SSF52733 1265 1608 4.32E-112 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1272 1609 34.639 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 Pfam PF02277 Phosphoribosyltransferase 1270 1607 5.4E-124 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 Pfam PF00881 Nitroreductase family 1052 1219 5.2E-31 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 Gene3D G3DSA:3.40.50.10210 1332 1590 3.3E-105 T 28-03-2018 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 Gene3D G3DSA:3.40.109.10 1039 1254 3.2E-45 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 SUPERFAMILY SSF55469 1048 1251 2.75E-52 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS07660 1fba81f0315c60d7711614d49b3f07ab 1610 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 1040 1245 2.1E-91 T 28-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 SMD44_RS38870 b0c5a1add1ee298b54b82d1f16e5bb6c 492 Gene3D G3DSA:3.40.50.720 162 286 2.0E-14 T 28-03-2018 SMD44_RS38870 b0c5a1add1ee298b54b82d1f16e5bb6c 492 Pfam PF02397 Bacterial sugar transferase 299 487 8.0E-63 T 28-03-2018 IPR003362 Bacterial sugar transferase SMD44_RS38870 b0c5a1add1ee298b54b82d1f16e5bb6c 492 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 41 492 7.6E-120 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase SMD44_RS38870 b0c5a1add1ee298b54b82d1f16e5bb6c 492 Pfam PF13727 CoA-binding domain 109 230 5.2E-7 T 28-03-2018 SMD44_RS20710 885e174be04fe8b02acd9f2328e33f5f 201 Pfam PF04314 Copper chaperone PCu(A)C 64 158 5.3E-28 T 28-03-2018 IPR007410 Copper chaperone PCuAC SMD44_RS20710 885e174be04fe8b02acd9f2328e33f5f 201 SUPERFAMILY SSF110087 49 165 5.1E-30 T 28-03-2018 IPR007410 Copper chaperone PCuAC SMD44_RS20710 885e174be04fe8b02acd9f2328e33f5f 201 Gene3D G3DSA:3.40.190.10 3 160 1.4E-7 T 28-03-2018 SMD44_RS36095 01c5ebc87d356c097073c85693b60d27 188 SUPERFAMILY SSF47598 119 165 1.41E-7 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMD44_RS36095 01c5ebc87d356c097073c85693b60d27 188 Gene3D G3DSA:1.10.1220.10 119 157 1.2E-10 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS43290 6aa0a97b3fe2d264e6dc844dbf278b82 432 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 273 279 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD44_RS43290 6aa0a97b3fe2d264e6dc844dbf278b82 432 Gene3D G3DSA:3.40.50.150 137 389 4.6E-26 T 28-03-2018 SMD44_RS43290 6aa0a97b3fe2d264e6dc844dbf278b82 432 Pfam PF02384 N-6 DNA Methylase 131 335 2.3E-6 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMD44_RS43290 6aa0a97b3fe2d264e6dc844dbf278b82 432 SUPERFAMILY SSF53335 56 384 3.1E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS43290 6aa0a97b3fe2d264e6dc844dbf278b82 432 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 270 282 1.6E-7 T 28-03-2018 SMD44_RS43290 6aa0a97b3fe2d264e6dc844dbf278b82 432 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 166 180 1.6E-7 T 28-03-2018 SMD44_RS43290 6aa0a97b3fe2d264e6dc844dbf278b82 432 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 135 151 1.6E-7 T 28-03-2018 SMD44_RS34260 dd5ad24269c86ddfda69302741e5d913 250 Pfam PF14494 Domain of unknown function (DUF4436) 4 238 1.0E-72 T 28-03-2018 IPR027948 Protein of unknown function (DUF4436) SMD44_RS01000 8d97e08d907e8b744f3fc4230f56cecf 245 SUPERFAMILY SSF48498 88 235 4.45E-29 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS01000 8d97e08d907e8b744f3fc4230f56cecf 245 Gene3D G3DSA:1.10.10.60 1 63 3.8E-14 T 28-03-2018 SMD44_RS01000 8d97e08d907e8b744f3fc4230f56cecf 245 SUPERFAMILY SSF46689 9 81 1.95E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01000 8d97e08d907e8b744f3fc4230f56cecf 245 Gene3D G3DSA:1.10.357.10 64 237 1.8E-36 T 28-03-2018 SMD44_RS01000 8d97e08d907e8b744f3fc4230f56cecf 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 6.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS12695 e2093ab4d7cde731d7fa9258fad36e1e 152 PIRSF PIRSF000239 1 152 1.6E-29 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD44_RS12695 e2093ab4d7cde731d7fa9258fad36e1e 152 Gene3D G3DSA:3.40.30.10 1 152 1.3E-38 T 28-03-2018 SMD44_RS12695 e2093ab4d7cde731d7fa9258fad36e1e 152 SUPERFAMILY SSF52833 3 152 1.12E-47 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS12695 e2093ab4d7cde731d7fa9258fad36e1e 152 Pfam PF00578 AhpC/TSA family 5 130 2.2E-39 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD44_RS03660 9cf828acb7eff8c89f1c2826bbf639e7 294 PIRSF PIRSF006648 2 60 7.1 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS03660 9cf828acb7eff8c89f1c2826bbf639e7 294 PIRSF PIRSF006648 28 278 9.9E-15 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS03660 9cf828acb7eff8c89f1c2826bbf639e7 294 Pfam PF01061 ABC-2 type transporter 39 232 1.0E-15 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS11290 cfb76b0c87560012587000796a86ce1b 380 Pfam PF13439 Glycosyltransferase Family 4 16 178 6.0E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS11290 cfb76b0c87560012587000796a86ce1b 380 Gene3D G3DSA:3.40.50.2000 161 367 6.7E-53 T 28-03-2018 SMD44_RS11290 cfb76b0c87560012587000796a86ce1b 380 Pfam PF00534 Glycosyl transferases group 1 197 362 2.4E-41 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS11290 cfb76b0c87560012587000796a86ce1b 380 SUPERFAMILY SSF53756 5 380 1.45E-75 T 28-03-2018 SMD44_RS15600 0163e785aaa61a8c6a369aed3a11dc57 507 SUPERFAMILY SSF103473 42 481 5.36E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS15600 0163e785aaa61a8c6a369aed3a11dc57 507 Pfam PF00083 Sugar (and other) transporter 61 482 3.3E-47 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD44_RS15600 0163e785aaa61a8c6a369aed3a11dc57 507 ProSitePatterns PS00217 Sugar transport proteins signature 2. 167 192 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS15600 0163e785aaa61a8c6a369aed3a11dc57 507 ProSitePatterns PS00216 Sugar transport proteins signature 1. 349 365 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS15600 0163e785aaa61a8c6a369aed3a11dc57 507 Gene3D G3DSA:1.20.1250.20 52 268 5.1E-27 T 28-03-2018 SMD44_RS15600 0163e785aaa61a8c6a369aed3a11dc57 507 Gene3D G3DSA:1.20.1250.20 269 504 1.0E-23 T 28-03-2018 SMD44_RS27210 cf7765a43881c63311b502beb5d13992 403 Gene3D G3DSA:3.90.1150.10 279 403 2.0E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS27210 cf7765a43881c63311b502beb5d13992 403 SUPERFAMILY SSF53383 7 398 1.3E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS27210 cf7765a43881c63311b502beb5d13992 403 Pfam PF00155 Aminotransferase class I and II 34 393 9.7E-52 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS27210 cf7765a43881c63311b502beb5d13992 403 Gene3D G3DSA:3.40.640.10 52 278 4.5E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS27655 311a05be05a47a8de61fc507982c4c70 278 Gene3D G3DSA:1.10.1060.10 128 264 4.1E-10 T 28-03-2018 SMD44_RS27655 311a05be05a47a8de61fc507982c4c70 278 SUPERFAMILY SSF46548 145 253 2.09E-18 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD44_RS27655 311a05be05a47a8de61fc507982c4c70 278 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 41 246 4.2E-42 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS27655 311a05be05a47a8de61fc507982c4c70 278 SUPERFAMILY SSF54292 42 125 1.06E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS27655 311a05be05a47a8de61fc507982c4c70 278 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 30 126 7.4E-25 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS27655 311a05be05a47a8de61fc507982c4c70 278 Pfam PF13183 4Fe-4S dicluster domain 162 243 3.2E-14 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS27655 311a05be05a47a8de61fc507982c4c70 278 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 75 83 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD44_RS27655 311a05be05a47a8de61fc507982c4c70 278 Gene3D G3DSA:3.10.20.30 19 125 2.8E-26 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS27535 81993f14505c43141bd43ecfd0f40f3d 84 Gene3D G3DSA:1.10.287.1040 11 77 4.6E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD44_RS27535 81993f14505c43141bd43ecfd0f40f3d 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 11 52 1.0E-14 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD44_RS27535 81993f14505c43141bd43ecfd0f40f3d 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 14 67 1.5E-19 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD44_RS27535 81993f14505c43141bd43ecfd0f40f3d 84 PIRSF PIRSF006488 2 83 2.5E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD44_RS27535 81993f14505c43141bd43ecfd0f40f3d 84 SUPERFAMILY SSF116842 8 68 8.5E-16 T 28-03-2018 SMD44_RS27535 81993f14505c43141bd43ecfd0f40f3d 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 13 73 13.72 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD44_RS27535 81993f14505c43141bd43ecfd0f40f3d 84 Pfam PF02609 Exonuclease VII small subunit 14 63 9.8E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD44_RS13220 7a9ff2767c7241c6984c94f7f3316a15 73 Gene3D G3DSA:1.10.150.20 5 73 2.4E-4 T 28-03-2018 SMD44_RS03895 e95946a65d799289ea087c50c33e1f1d 165 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 164 34.458 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SMD44_RS03895 e95946a65d799289ea087c50c33e1f1d 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 84 163 5.5E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS03895 e95946a65d799289ea087c50c33e1f1d 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 83 163 2.0E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS03895 e95946a65d799289ea087c50c33e1f1d 165 SUPERFAMILY SSF53155 3 88 9.02E-10 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS03895 e95946a65d799289ea087c50c33e1f1d 165 Gene3D G3DSA:3.30.160.70 1 81 2.1E-18 T 28-03-2018 SMD44_RS03895 e95946a65d799289ea087c50c33e1f1d 165 Gene3D G3DSA:1.10.10.10 82 165 2.9E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03895 e95946a65d799289ea087c50c33e1f1d 165 SUPERFAMILY SSF46767 82 163 3.79E-28 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS09095 fa4969535a913e0a200f7649e7683419 206 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 10 173 1.1E-29 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SMD44_RS09095 fa4969535a913e0a200f7649e7683419 206 Pfam PF04079 Segregation and condensation complex subunit ScpB 13 170 1.7E-56 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SMD44_RS09095 fa4969535a913e0a200f7649e7683419 206 SUPERFAMILY SSF46785 88 161 7.68E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09095 fa4969535a913e0a200f7649e7683419 206 PIRSF PIRSF019345 1 201 1.7E-53 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SMD44_RS09095 fa4969535a913e0a200f7649e7683419 206 Gene3D G3DSA:1.10.10.10 2 87 4.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09095 fa4969535a913e0a200f7649e7683419 206 SUPERFAMILY SSF46785 8 83 1.64E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09095 fa4969535a913e0a200f7649e7683419 206 Gene3D G3DSA:1.10.10.10 88 178 9.0E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14395 c822c15c0144204062932c364a8acac1 316 Gene3D G3DSA:1.10.3720.10 37 283 1.4E-21 T 28-03-2018 SMD44_RS14395 c822c15c0144204062932c364a8acac1 316 SUPERFAMILY SSF161098 82 263 1.7E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS14395 c822c15c0144204062932c364a8acac1 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 265 1.7E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 Pfam PF01568 Molydopterin dinucleotide binding domain 597 703 4.7E-33 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 SUPERFAMILY SSF53706 12 598 6.67E-168 T 28-03-2018 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 SMART SM00926 13 66 2.4E-8 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 Gene3D G3DSA:2.20.25.90 8 67 4.9E-15 T 28-03-2018 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 14 62 1.4E-10 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 SUPERFAMILY SSF50692 559 708 1.33E-47 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 Pfam PF00384 Molybdopterin oxidoreductase 69 495 1.5E-72 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 Gene3D G3DSA:3.40.50.740 69 175 2.1E-23 T 28-03-2018 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 Gene3D G3DSA:2.40.40.20 553 709 7.2E-46 T 28-03-2018 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 Gene3D G3DSA:3.40.228.10 176 267 1.8E-26 T 28-03-2018 SMD44_RS13355 ba5c2797c0f29cd33a5076bdda8817a2 712 Gene3D G3DSA:3.40.50.740 268 552 3.3E-68 T 28-03-2018 SMD44_RS10275 a1ea75d462726f806fa19b3b851f03f2 312 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 17 311 39.284 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 SMD44_RS10275 a1ea75d462726f806fa19b3b851f03f2 312 SUPERFAMILY SSF110581 12 310 6.54E-101 T 28-03-2018 SMD44_RS10275 a1ea75d462726f806fa19b3b851f03f2 312 Pfam PF04227 Indigoidine synthase A like protein 18 307 1.8E-114 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 SMD44_RS10275 a1ea75d462726f806fa19b3b851f03f2 312 Gene3D G3DSA:3.40.1790.10 6 312 3.9E-123 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 SMD44_RS43750 422e396fd0d4477892fcdc5c90d1af85 334 SUPERFAMILY SSF54919 9 156 5.37E-26 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS43750 422e396fd0d4477892fcdc5c90d1af85 334 SUPERFAMILY SSF54919 167 316 5.11E-25 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS43750 422e396fd0d4477892fcdc5c90d1af85 334 Pfam PF00334 Nucleoside diphosphate kinase 11 156 1.8E-20 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS43750 422e396fd0d4477892fcdc5c90d1af85 334 Pfam PF00334 Nucleoside diphosphate kinase 168 315 4.6E-20 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS43750 422e396fd0d4477892fcdc5c90d1af85 334 Gene3D G3DSA:3.30.70.141 3 160 1.6E-27 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS43750 422e396fd0d4477892fcdc5c90d1af85 334 Gene3D G3DSA:3.30.70.141 163 322 3.1E-27 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS43750 422e396fd0d4477892fcdc5c90d1af85 334 SMART SM00562 11 161 1.0E-7 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS43750 422e396fd0d4477892fcdc5c90d1af85 334 SMART SM00562 165 322 1.7E-7 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS38995 2fc86a3b06ea4364ff11931479e85d3b 344 PIRSF PIRSF005644 10 344 1.7E-103 T 28-03-2018 IPR011854 Hydrogenase expression/formation protein HypE SMD44_RS38995 2fc86a3b06ea4364ff11931479e85d3b 344 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 15 344 3.6E-115 T 28-03-2018 IPR011854 Hydrogenase expression/formation protein HypE SMD44_RS38995 2fc86a3b06ea4364ff11931479e85d3b 344 Gene3D G3DSA:3.30.1330.10 11 160 2.8E-19 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS38995 2fc86a3b06ea4364ff11931479e85d3b 344 SUPERFAMILY SSF56042 168 340 6.73E-39 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS38995 2fc86a3b06ea4364ff11931479e85d3b 344 SUPERFAMILY SSF55326 16 157 1.53E-25 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS38995 2fc86a3b06ea4364ff11931479e85d3b 344 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 320 2.9E-22 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS38995 2fc86a3b06ea4364ff11931479e85d3b 344 Gene3D G3DSA:3.90.650.10 165 332 4.2E-37 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS38995 2fc86a3b06ea4364ff11931479e85d3b 344 Pfam PF00586 AIR synthase related protein, N-terminal domain 47 156 1.3E-14 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS27045 51b324b7e739816098e7a587755d8af5 124 Gene3D G3DSA:3.10.450.50 7 115 1.2E-15 T 28-03-2018 SMD44_RS27045 51b324b7e739816098e7a587755d8af5 124 Pfam PF12680 SnoaL-like domain 16 106 5.0E-9 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS27045 51b324b7e739816098e7a587755d8af5 124 SUPERFAMILY SSF54427 9 116 4.19E-20 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 Gene3D G3DSA:2.160.20.10 235 368 6.5E-12 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SUPERFAMILY SSF52540 539 751 1.01E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00382 577 716 5.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00722 313 474 4.6E-5 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00722 41 172 15.0 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SUPERFAMILY SSF51126 346 473 2.95E-12 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 267 289 3900.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 453 475 7400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 221 243 1200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 128 150 53.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 362 383 8800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 430 452 870.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 174 196 37.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 316 337 8300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 244 266 5400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 151 173 620.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 198 220 5300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 385 406 540.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 407 429 12.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SMART SM00710 339 361 3400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 PRINTS PR00819 CbxX/CfqX superfamily signature 758 770 3.0E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 PRINTS PR00819 CbxX/CfqX superfamily signature 540 554 3.0E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 PRINTS PR00819 CbxX/CfqX superfamily signature 663 675 3.0E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 PRINTS PR00819 CbxX/CfqX superfamily signature 618 632 3.0E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 PRINTS PR00819 CbxX/CfqX superfamily signature 701 720 3.0E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 PRINTS PR00819 CbxX/CfqX superfamily signature 684 701 3.0E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 PRINTS PR00819 CbxX/CfqX superfamily signature 632 651 3.0E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 PRINTS PR00819 CbxX/CfqX superfamily signature 580 595 3.0E-48 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 Gene3D G3DSA:2.160.20.10 369 495 3.7E-14 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SUPERFAMILY SSF51126 206 362 1.82E-8 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 SUPERFAMILY SSF51126 20 239 8.87E-26 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 Pfam PF13229 Right handed beta helix region 121 242 7.3E-14 T 28-03-2018 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 Pfam PF13229 Right handed beta helix region 356 474 1.8E-10 T 28-03-2018 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 Gene3D G3DSA:2.160.20.10 8 234 1.9E-31 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 Gene3D G3DSA:3.40.50.300 516 713 7.9E-25 T 28-03-2018 SMD44_RS03980 c7b5f1f94f0ee13b8988022288a8b238 803 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 582 712 2.0E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 Gene3D G3DSA:1.10.357.10 84 210 5.8E-20 T 28-03-2018 SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 SUPERFAMILY SSF48498 92 210 2.84E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 91 201 2.0E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 SUPERFAMILY SSF46689 10 78 1.05E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.1E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 Gene3D G3DSA:1.10.260.40 49 83 0.0024 T 28-03-2018 SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS12080 5ae1a836e4ec824b5ee55320c2d5e736 210 Gene3D G3DSA:1.10.10.60 5 48 1.5E-17 T 28-03-2018 SMD44_RS14735 bbc9d3bc0a90857a8e9a7a3b238d7923 307 Gene3D G3DSA:3.20.20.150 1 307 2.7E-50 T 28-03-2018 SMD44_RS14735 bbc9d3bc0a90857a8e9a7a3b238d7923 307 SUPERFAMILY SSF51658 9 304 4.28E-50 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS14735 bbc9d3bc0a90857a8e9a7a3b238d7923 307 Pfam PF01261 Xylose isomerase-like TIM barrel 41 243 3.0E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS10410 2e20625a56737b01d082f64819b42721 445 SUPERFAMILY SSF103473 39 424 7.85E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS10410 2e20625a56737b01d082f64819b42721 445 Gene3D G3DSA:1.20.1250.20 13 235 1.0E-14 T 28-03-2018 SMD44_RS10410 2e20625a56737b01d082f64819b42721 445 ProSitePatterns PS00216 Sugar transport proteins signature 1. 300 316 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS10410 2e20625a56737b01d082f64819b42721 445 Gene3D G3DSA:1.20.1250.20 236 436 1.4E-22 T 28-03-2018 SMD44_RS10410 2e20625a56737b01d082f64819b42721 445 Pfam PF07690 Major Facilitator Superfamily 46 280 8.4E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS31145 eb664c65c4ba2e0bb06c9fbd5d5dc67d 171 SUPERFAMILY SSF142433 1 152 2.75E-42 T 28-03-2018 IPR008136 CinA, C-terminal SMD44_RS31145 eb664c65c4ba2e0bb06c9fbd5d5dc67d 171 Gene3D G3DSA:3.90.950.20 1 157 7.6E-57 T 28-03-2018 SMD44_RS31145 eb664c65c4ba2e0bb06c9fbd5d5dc67d 171 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 4 152 2.3E-34 T 28-03-2018 IPR008136 CinA, C-terminal SMD44_RS31145 eb664c65c4ba2e0bb06c9fbd5d5dc67d 171 Pfam PF02464 Competence-damaged protein 2 151 1.8E-45 T 28-03-2018 IPR008136 CinA, C-terminal SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 Gene3D G3DSA:1.10.10.10 3 90 4.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 80 8.0E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 Pfam PF00155 Aminotransferase class I and II 136 436 2.4E-17 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 Gene3D G3DSA:3.90.1150.10 346 469 1.4E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 SMART SM00345 21 80 2.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 SUPERFAMILY SSF46785 13 82 5.96E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 SUPERFAMILY SSF53383 109 467 2.8E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 Gene3D G3DSA:3.40.640.10 133 345 4.2E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 4.6E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS15245 d19c807d5bbe31c002a037af635ef7d5 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 4.6E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS39545 6937c263f3f75d1cfc1b5a249ff48a60 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS39545 6937c263f3f75d1cfc1b5a249ff48a60 184 SUPERFAMILY SSF48498 81 182 8.9E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS39545 6937c263f3f75d1cfc1b5a249ff48a60 184 Gene3D G3DSA:1.10.260.40 40 63 5.1E-10 T 28-03-2018 SMD44_RS39545 6937c263f3f75d1cfc1b5a249ff48a60 184 SUPERFAMILY SSF46689 2 81 4.64E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS39545 6937c263f3f75d1cfc1b5a249ff48a60 184 Gene3D G3DSA:1.10.357.10 64 184 1.3E-8 T 28-03-2018 SMD44_RS39545 6937c263f3f75d1cfc1b5a249ff48a60 184 Gene3D G3DSA:1.10.10.60 3 39 1.7E-9 T 28-03-2018 SMD44_RS06895 e86986d806fc3c000da62f16310d5122 196 Pfam PF04186 FxsA cytoplasmic membrane protein 27 136 3.3E-27 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 SMD44_RS07310 103427969857789e769e9aa20593242e 348 SUPERFAMILY SSF52540 169 341 1.73E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07310 103427969857789e769e9aa20593242e 348 Gene3D G3DSA:3.40.50.300 167 344 4.5E-17 T 28-03-2018 SMD44_RS07310 103427969857789e769e9aa20593242e 348 Pfam PF13671 AAA domain 169 304 4.1E-8 T 28-03-2018 SMD44_RS07310 103427969857789e769e9aa20593242e 348 PRINTS PR01217 Proline rich extensin signature 67 83 5.6E-11 T 28-03-2018 SMD44_RS07310 103427969857789e769e9aa20593242e 348 PRINTS PR01217 Proline rich extensin signature 23 35 5.6E-11 T 28-03-2018 SMD44_RS07310 103427969857789e769e9aa20593242e 348 PRINTS PR01217 Proline rich extensin signature 3 19 5.6E-11 T 28-03-2018 SMD44_RS07310 103427969857789e769e9aa20593242e 348 PRINTS PR01217 Proline rich extensin signature 40 61 5.6E-11 T 28-03-2018 SMD44_RS07310 103427969857789e769e9aa20593242e 348 PRINTS PR01217 Proline rich extensin signature 85 102 5.6E-11 T 28-03-2018 SMD44_RS07310 103427969857789e769e9aa20593242e 348 PRINTS PR01217 Proline rich extensin signature 111 136 5.6E-11 T 28-03-2018 SMD44_RS05585 0ddd3494a80c472eda629dc50f353abf 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 61 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS05585 0ddd3494a80c472eda629dc50f353abf 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05585 0ddd3494a80c472eda629dc50f353abf 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05585 0ddd3494a80c472eda629dc50f353abf 215 Gene3D G3DSA:1.10.357.10 66 208 1.1E-19 T 28-03-2018 SMD44_RS05585 0ddd3494a80c472eda629dc50f353abf 215 SUPERFAMILY SSF46689 8 89 6.48E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05585 0ddd3494a80c472eda629dc50f353abf 215 Gene3D G3DSA:1.10.10.60 5 65 2.1E-17 T 28-03-2018 SMD44_RS05585 0ddd3494a80c472eda629dc50f353abf 215 SUPERFAMILY SSF48498 87 201 3.71E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS05585 0ddd3494a80c472eda629dc50f353abf 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 4.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 Gene3D G3DSA:3.40.50.2300 1 146 1.0E-25 T 28-03-2018 SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 Gene3D G3DSA:1.10.10.10 147 213 4.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 SUPERFAMILY SSF52172 1 174 1.49E-18 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 Pfam PF00072 Response regulator receiver domain 3 108 2.0E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 197 8.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 SMART SM00448 1 120 1.5E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS05945 0e8e2b68128d09cddc7390f938dfe0f5 214 SMART SM00421 148 205 1.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS24125 691f93aba2bba86e34b00e552fa4503b 257 Gene3D G3DSA:1.10.1740.10 74 169 1.1E-24 T 28-03-2018 SMD44_RS24125 691f93aba2bba86e34b00e552fa4503b 257 Pfam PF04542 Sigma-70 region 2 98 165 1.3E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24125 691f93aba2bba86e34b00e552fa4503b 257 Pfam PF08281 Sigma-70, region 4 197 248 1.7E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24125 691f93aba2bba86e34b00e552fa4503b 257 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 93 250 1.4E-29 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24125 691f93aba2bba86e34b00e552fa4503b 257 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 83 252 9.4E-79 T 28-03-2018 IPR014298 RNA polymerase sigma-X type SMD44_RS24125 691f93aba2bba86e34b00e552fa4503b 257 SUPERFAMILY SSF88946 76 184 2.35E-27 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24125 691f93aba2bba86e34b00e552fa4503b 257 Gene3D G3DSA:1.10.10.10 170 255 1.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24125 691f93aba2bba86e34b00e552fa4503b 257 SUPERFAMILY SSF88659 182 252 2.24E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS33475 580383087bcaa3ce7da58894598cec71 548 Pfam PF13649 Methyltransferase domain 61 158 1.9E-13 T 28-03-2018 SMD44_RS33475 580383087bcaa3ce7da58894598cec71 548 Gene3D G3DSA:3.40.50.150 40 262 2.3E-22 T 28-03-2018 SMD44_RS33475 580383087bcaa3ce7da58894598cec71 548 Gene3D G3DSA:1.10.287.840 283 326 6.5E-15 T 28-03-2018 IPR023143 Mycolic acid cyclopropane synthase-like domain SMD44_RS33475 580383087bcaa3ce7da58894598cec71 548 Gene3D G3DSA:1.10.287.840 453 539 4.9E-31 T 28-03-2018 IPR023143 Mycolic acid cyclopropane synthase-like domain SMD44_RS33475 580383087bcaa3ce7da58894598cec71 548 SUPERFAMILY SSF53335 279 545 9.85E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS33475 580383087bcaa3ce7da58894598cec71 548 Pfam PF08241 Methyltransferase domain 337 435 1.9E-20 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS33475 580383087bcaa3ce7da58894598cec71 548 SUPERFAMILY SSF53335 30 260 2.01E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS33475 580383087bcaa3ce7da58894598cec71 548 Gene3D G3DSA:3.40.50.150 327 452 6.1E-20 T 28-03-2018 SMD44_RS02410 ad965349b5992e83c5444d3b3f8e3f2c 427 Pfam PF00144 Beta-lactamase 55 386 4.4E-54 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS02410 ad965349b5992e83c5444d3b3f8e3f2c 427 Gene3D G3DSA:3.40.710.10 41 397 3.2E-72 T 28-03-2018 SMD44_RS02410 ad965349b5992e83c5444d3b3f8e3f2c 427 SUPERFAMILY SSF56601 47 381 1.71E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS37950 b195d2ccdfb3dcb0d0cfbe166f69cbba 514 Gene3D G3DSA:3.40.50.300 263 500 8.1E-9 T 28-03-2018 SMD44_RS32940 b14351a2c638911c50fb84879cac4bdf 581 SUPERFAMILY SSF49319 345 473 2.26E-14 T 28-03-2018 IPR027273 Neocarzinostatin-like SMD44_RS32940 b14351a2c638911c50fb84879cac4bdf 581 Gene3D G3DSA:2.60.40.230 343 473 5.9E-33 T 28-03-2018 SMD44_RS32940 b14351a2c638911c50fb84879cac4bdf 581 Gene3D G3DSA:2.60.40.10 253 333 3.4E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS32940 b14351a2c638911c50fb84879cac4bdf 581 SUPERFAMILY SSF48726 240 333 6.25E-9 T 28-03-2018 IPR007110 Immunoglobulin-like domain SMD44_RS32940 b14351a2c638911c50fb84879cac4bdf 581 Gene3D G3DSA:2.130.10.10 117 252 0.0013 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS32940 b14351a2c638911c50fb84879cac4bdf 581 SUPERFAMILY SSF50969 39 242 5.57E-13 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMD44_RS08305 49568a7676e187fd906f507c8ea7a57d 196 Pfam PF11290 Protein of unknown function (DUF3090) 7 186 1.7E-67 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 SMD44_RS08305 49568a7676e187fd906f507c8ea7a57d 196 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 190 5.8E-78 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 SMD44_RS42980 f50441861608e5d0ab762feb1dac9ef6 221 Gene3D G3DSA:3.40.1130.10 5 214 3.6E-32 T 28-03-2018 SMD44_RS42980 f50441861608e5d0ab762feb1dac9ef6 221 Pfam PF01553 Acyltransferase 28 148 4.7E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS42980 f50441861608e5d0ab762feb1dac9ef6 221 SMART SM00563 30 152 5.4E-21 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS42980 f50441861608e5d0ab762feb1dac9ef6 221 SUPERFAMILY SSF69593 29 206 1.57E-23 T 28-03-2018 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 Gene3D G3DSA:1.10.287.130 217 269 7.1E-7 T 28-03-2018 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 Pfam PF00672 HAMP domain 175 222 2.0E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 Gene3D G3DSA:3.30.565.10 270 437 1.0E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 229 277 1.7E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 SUPERFAMILY SSF158472 175 223 3.53E-5 T 28-03-2018 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 SUPERFAMILY SSF47384 211 281 3.92E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 1.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 1.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 439 1.3E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 SMART SM00304 174 226 3.0E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 SUPERFAMILY SSF55874 313 439 1.01E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 SMART SM00387 336 441 3.6E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15075 4a1f85b1b57b41747b09a49a22462ebc 476 SMART SM00388 227 285 2.3E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS25360 cfa90240030e9392338f6d5ba117a004 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25360 cfa90240030e9392338f6d5ba117a004 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 4.5E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25360 cfa90240030e9392338f6d5ba117a004 54 Pfam PF00471 Ribosomal protein L33 9 54 3.4E-23 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25360 cfa90240030e9392338f6d5ba117a004 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.836 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25360 cfa90240030e9392338f6d5ba117a004 54 SUPERFAMILY SSF57829 4 54 4.21E-20 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMD44_RS09225 5c1957ad87c4c999d9fc505763eb014d 278 Gene3D G3DSA:1.25.40.10 4 109 5.7E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS09225 5c1957ad87c4c999d9fc505763eb014d 278 SUPERFAMILY SSF48452 45 116 1.16E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS09225 5c1957ad87c4c999d9fc505763eb014d 278 SUPERFAMILY SSF48452 158 193 1.16E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS09225 5c1957ad87c4c999d9fc505763eb014d 278 Pfam PF14559 Tetratricopeptide repeat 135 193 1.2E-6 T 28-03-2018 SMD44_RS09225 5c1957ad87c4c999d9fc505763eb014d 278 Gene3D G3DSA:1.25.40.10 110 208 2.5E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS35475 2064096ed551d8c4c0c4ceddf5aeae23 250 Pfam PF00483 Nucleotidyl transferase 3 154 5.0E-10 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD44_RS35475 2064096ed551d8c4c0c4ceddf5aeae23 250 SUPERFAMILY SSF53448 1 242 1.17E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS35475 2064096ed551d8c4c0c4ceddf5aeae23 250 Gene3D G3DSA:3.90.550.10 1 249 1.4E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS30170 a979f94389ae26a5650fa4cae033029e 1118 SUPERFAMILY SSF55874 579 697 3.01E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS30170 a979f94389ae26a5650fa4cae033029e 1118 Pfam PF00672 HAMP domain 406 473 3.7E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS30170 a979f94389ae26a5650fa4cae033029e 1118 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 591 698 3.7E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS30170 a979f94389ae26a5650fa4cae033029e 1118 Pfam PF08376 Nitrate and nitrite sensing 104 367 4.9E-40 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein SMD44_RS30170 a979f94389ae26a5650fa4cae033029e 1118 Gene3D G3DSA:3.30.565.10 509 698 8.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS30170 a979f94389ae26a5650fa4cae033029e 1118 SMART SM00304 406 476 0.0017 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS30170 a979f94389ae26a5650fa4cae033029e 1118 SMART SM00387 588 700 3.1E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13845 15c5a4f59adc5496c75a21b943fc039b 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.559 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS13845 15c5a4f59adc5496c75a21b943fc039b 86 Gene3D G3DSA:1.20.58.110 1 86 3.4E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS13845 15c5a4f59adc5496c75a21b943fc039b 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 71 3.0E-20 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS13845 15c5a4f59adc5496c75a21b943fc039b 86 SUPERFAMILY SSF46992 3 85 1.7E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS13845 15c5a4f59adc5496c75a21b943fc039b 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 82 1.1E-22 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS13845 15c5a4f59adc5496c75a21b943fc039b 86 Pfam PF01649 Ribosomal protein S20 2 82 1.0E-25 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS28230 1cada923c0ddd1e22dfa5587896ddc4d 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 1.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28230 1cada923c0ddd1e22dfa5587896ddc4d 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 8.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28230 1cada923c0ddd1e22dfa5587896ddc4d 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 8.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28230 1cada923c0ddd1e22dfa5587896ddc4d 216 SUPERFAMILY SSF46689 3 80 8.48E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS28230 1cada923c0ddd1e22dfa5587896ddc4d 216 Gene3D G3DSA:1.10.10.60 2 42 2.9E-15 T 28-03-2018 SMD44_RS28230 1cada923c0ddd1e22dfa5587896ddc4d 216 Gene3D G3DSA:1.10.10.60 43 86 5.8E-11 T 28-03-2018 SMD44_RS20030 3a996f4481956e78295ae4ac116a5f9e 299 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 295 25.592 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS20030 3a996f4481956e78295ae4ac116a5f9e 299 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS20030 3a996f4481956e78295ae4ac116a5f9e 299 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 19 298 9.0E-71 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 SMD44_RS20030 3a996f4481956e78295ae4ac116a5f9e 299 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS20030 3a996f4481956e78295ae4ac116a5f9e 299 Gene3D G3DSA:3.30.470.20 113 247 1.8E-56 T 28-03-2018 SMD44_RS20030 3a996f4481956e78295ae4ac116a5f9e 299 SUPERFAMILY SSF56104 13 298 2.88E-99 T 28-03-2018 SMD44_RS20030 3a996f4481956e78295ae4ac116a5f9e 299 Pfam PF01259 SAICAR synthetase 19 269 1.2E-101 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD44_RS20030 3a996f4481956e78295ae4ac116a5f9e 299 Gene3D G3DSA:3.30.200.20 15 112 2.8E-36 T 28-03-2018 SMD44_RS16090 5b50e142d7cd386d6602cbb9a2fea44a 446 Gene3D G3DSA:3.40.190.10 49 177 2.1E-20 T 28-03-2018 SMD44_RS16090 5b50e142d7cd386d6602cbb9a2fea44a 446 SUPERFAMILY SSF53850 46 444 2.9E-53 T 28-03-2018 SMD44_RS16090 5b50e142d7cd386d6602cbb9a2fea44a 446 Pfam PF13416 Bacterial extracellular solute-binding protein 66 375 1.9E-21 T 28-03-2018 SMD44_RS16090 5b50e142d7cd386d6602cbb9a2fea44a 446 Gene3D G3DSA:3.40.190.10 178 398 4.6E-37 T 28-03-2018 SMD44_RS43820 506dce6a8ed0a54ae391a84437cd429f 316 SUPERFAMILY SSF48576 10 310 2.36E-40 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS43820 506dce6a8ed0a54ae391a84437cd429f 316 Gene3D G3DSA:1.10.600.10 6 310 1.6E-52 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS01320 80b95ab45c595fe8f98530d2ec628f25 266 PIRSF PIRSF017393 1 266 1.7E-100 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS01320 80b95ab45c595fe8f98530d2ec628f25 266 SUPERFAMILY SSF53335 13 250 4.59E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS01320 80b95ab45c595fe8f98530d2ec628f25 266 Pfam PF04672 S-adenosyl methyltransferase 6 266 2.4E-105 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS01320 80b95ab45c595fe8f98530d2ec628f25 266 Gene3D G3DSA:3.40.50.150 1 266 6.9E-49 T 28-03-2018 SMD44_RS41765 1fa6069a8589cd152531084347b87aa7 193 SMART SM00554 95 192 2.1E-32 T 28-03-2018 IPR000782 FAS1 domain SMD44_RS41765 1fa6069a8589cd152531084347b87aa7 193 Pfam PF02469 Fasciclin domain 71 191 1.6E-33 T 28-03-2018 IPR000782 FAS1 domain SMD44_RS41765 1fa6069a8589cd152531084347b87aa7 193 Gene3D G3DSA:2.30.180.10 58 193 4.3E-36 T 28-03-2018 IPR000782 FAS1 domain SMD44_RS41765 1fa6069a8589cd152531084347b87aa7 193 SUPERFAMILY SSF82153 54 191 1.83E-38 T 28-03-2018 IPR000782 FAS1 domain SMD44_RS20680 1037da2ab18fc20b061cbf1a1753f18e 135 SUPERFAMILY SSF52335 3 119 2.56E-43 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS20680 1037da2ab18fc20b061cbf1a1753f18e 135 PIRSF PIRSF006614 1 134 4.9E-47 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 SMD44_RS20680 1037da2ab18fc20b061cbf1a1753f18e 135 SMART SM00851 15 108 2.3E-18 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS20680 1037da2ab18fc20b061cbf1a1753f18e 135 Pfam PF02142 MGS-like domain 15 107 8.6E-17 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS20680 1037da2ab18fc20b061cbf1a1753f18e 135 Gene3D G3DSA:3.40.50.1380 1 124 2.5E-33 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain SMD44_RS20680 1037da2ab18fc20b061cbf1a1753f18e 135 ProSitePatterns PS01335 Methylglyoxal synthase active site. 55 63 - T 28-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 SMD44_RS21785 98c81d4946b0946b5ce4f07921846070 227 SUPERFAMILY SSF48498 75 221 1.56E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS21785 98c81d4946b0946b5ce4f07921846070 227 Gene3D G3DSA:1.10.357.10 63 224 4.9E-27 T 28-03-2018 SMD44_RS21785 98c81d4946b0946b5ce4f07921846070 227 SUPERFAMILY SSF46689 3 65 5.64E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS21785 98c81d4946b0946b5ce4f07921846070 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 2.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21785 98c81d4946b0946b5ce4f07921846070 227 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 70 220 9.1E-16 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS21785 98c81d4946b0946b5ce4f07921846070 227 Gene3D G3DSA:1.10.10.60 1 61 7.0E-13 T 28-03-2018 SMD44_RS07025 c41e3d3d442f9f9ae6f09e04819f22cd 215 PIRSF PIRSF000498 1 207 4.3E-70 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07025 c41e3d3d442f9f9ae6f09e04819f22cd 215 SUPERFAMILY SSF63380 2 88 1.28E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS07025 c41e3d3d442f9f9ae6f09e04819f22cd 215 SUPERFAMILY SSF63380 93 194 6.55E-34 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS07025 c41e3d3d442f9f9ae6f09e04819f22cd 215 Gene3D G3DSA:2.40.30.20 1 92 1.1E-27 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS07025 c41e3d3d442f9f9ae6f09e04819f22cd 215 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 193 1.2E-61 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07025 c41e3d3d442f9f9ae6f09e04819f22cd 215 Pfam PF00677 Lumazine binding domain 3 85 3.1E-23 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07025 c41e3d3d442f9f9ae6f09e04819f22cd 215 Pfam PF00677 Lumazine binding domain 99 183 6.0E-26 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD44_RS07025 c41e3d3d442f9f9ae6f09e04819f22cd 215 Gene3D G3DSA:2.40.30.20 93 190 5.3E-36 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS02710 35342d66515e63625968831435ce42aa 605 Pfam PF00664 ABC transporter transmembrane region 39 306 1.1E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS02710 35342d66515e63625968831435ce42aa 605 SUPERFAMILY SSF52540 358 600 6.82E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS02710 35342d66515e63625968831435ce42aa 605 Pfam PF00005 ABC transporter 382 529 2.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS02710 35342d66515e63625968831435ce42aa 605 SMART SM00382 389 575 2.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS02710 35342d66515e63625968831435ce42aa 605 Gene3D G3DSA:3.40.50.300 349 603 1.7E-68 T 28-03-2018 SMD44_RS02710 35342d66515e63625968831435ce42aa 605 Gene3D G3DSA:1.20.1560.10 1 337 6.8E-58 T 28-03-2018 SMD44_RS02710 35342d66515e63625968831435ce42aa 605 ProSitePatterns PS00211 ABC transporters family signature. 501 515 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS02710 35342d66515e63625968831435ce42aa 605 SUPERFAMILY SSF90123 27 329 2.62E-60 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS23760 e723e0a6e125fb96248485ced681676c 226 Gene3D G3DSA:1.10.3720.10 2 208 1.7E-27 T 28-03-2018 SMD44_RS23760 e723e0a6e125fb96248485ced681676c 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 207 2.0E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS23760 e723e0a6e125fb96248485ced681676c 226 SUPERFAMILY SSF161098 22 205 2.22E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 Gene3D G3DSA:3.40.50.970 257 528 2.7E-58 T 28-03-2018 SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 Gene3D G3DSA:3.40.50.920 538 644 1.4E-10 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 SUPERFAMILY SSF53323 38 261 5.36E-17 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 287 503 2.3E-52 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 Gene3D G3DSA:3.40.920.10 33 249 3.9E-41 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 SUPERFAMILY SSF52518 258 526 4.98E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 36 637 4.1E-198 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 544 615 7.4E-8 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 SUPERFAMILY SSF52922 542 643 1.02E-15 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS25240 80b06369a1d7f3da6ba52b577e33a242 644 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 44 232 1.2E-24 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SMD44_RS42910 831e5305733bd7fec05d37859c0e20dc 158 Pfam PF01478 Type IV leader peptidase family 30 126 1.9E-11 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 SMD44_RS42910 831e5305733bd7fec05d37859c0e20dc 158 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 85 95 2.2E-5 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMD44_RS42910 831e5305733bd7fec05d37859c0e20dc 158 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 32 49 2.2E-5 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMD44_RS42910 831e5305733bd7fec05d37859c0e20dc 158 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 96 107 2.2E-5 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMD44_RS26565 e83b1d567ca521c22377205f20a059d0 207 SUPERFAMILY SSF52980 25 173 1.39E-15 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS26565 e83b1d567ca521c22377205f20a059d0 207 Gene3D G3DSA:3.90.1570.10 10 200 5.0E-28 T 28-03-2018 SMD44_RS26565 e83b1d567ca521c22377205f20a059d0 207 Pfam PF05685 Putative restriction endonuclease 26 193 7.7E-30 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 Gene3D G3DSA:3.40.50.300 1 160 6.9E-24 T 28-03-2018 SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 ProSitePatterns PS01128 Shikimate kinase signature. 48 73 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 SUPERFAMILY SSF52540 1 155 2.11E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 Pfam PF01202 Shikimate kinase 1 155 4.3E-41 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 Hamap MF_00109 Shikimate kinase [aroK]. 1 156 21.038 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 PRINTS PR01100 Shikimate kinase family signature 85 102 1.8E-6 T 28-03-2018 SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 PRINTS PR01100 Shikimate kinase family signature 19 32 1.8E-6 T 28-03-2018 SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 PRINTS PR01100 Shikimate kinase family signature 47 55 1.8E-6 T 28-03-2018 SMD44_RS07320 cefe899a0cc3eb7fdefe6e23d6aa0d8b 160 PRINTS PR01100 Shikimate kinase family signature 65 74 1.8E-6 T 28-03-2018 SMD44_RS41220 aa845348d61279e873385e326792ec31 490 Gene3D G3DSA:1.20.1250.20 274 487 4.9E-20 T 28-03-2018 SMD44_RS41220 aa845348d61279e873385e326792ec31 490 SUPERFAMILY SSF103473 17 204 8.63E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS41220 aa845348d61279e873385e326792ec31 490 SUPERFAMILY SSF103473 262 479 8.63E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS41220 aa845348d61279e873385e326792ec31 490 Pfam PF07690 Major Facilitator Superfamily 27 428 1.2E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS41220 aa845348d61279e873385e326792ec31 490 Gene3D G3DSA:1.20.1250.20 11 213 7.1E-28 T 28-03-2018 SMD44_RS07590 00c34729524b237781c630507d5717f1 273 Gene3D G3DSA:3.30.470.10 1 125 1.7E-32 T 28-03-2018 SMD44_RS07590 00c34729524b237781c630507d5717f1 273 Pfam PF01063 Amino-transferase class IV 29 243 2.2E-49 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS07590 00c34729524b237781c630507d5717f1 273 SUPERFAMILY SSF56752 3 265 2.49E-69 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS07590 00c34729524b237781c630507d5717f1 273 ProSitePatterns PS00770 Aminotransferases class-IV signature. 174 203 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS07590 00c34729524b237781c630507d5717f1 273 Gene3D G3DSA:3.20.10.10 126 268 7.0E-44 T 28-03-2018 SMD44_RS28935 ccd403dc160ca48d4e3b9dffa962e2a8 251 PIRSF PIRSF006648 2 250 2.7E-40 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS28935 ccd403dc160ca48d4e3b9dffa962e2a8 251 Pfam PF01061 ABC-2 type transporter 12 215 9.1E-28 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS21665 4a1c9126d0e650d35cfb318e8543a246 383 Gene3D G3DSA:2.40.110.10 123 214 1.3E-12 T 28-03-2018 SMD44_RS21665 4a1c9126d0e650d35cfb318e8543a246 383 SUPERFAMILY SSF56645 2 220 2.88E-32 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS21665 4a1c9126d0e650d35cfb318e8543a246 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 369 1.1E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS21665 4a1c9126d0e650d35cfb318e8543a246 383 Gene3D G3DSA:1.10.540.10 1 122 8.2E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS21665 4a1c9126d0e650d35cfb318e8543a246 383 Gene3D G3DSA:1.20.140.10 215 377 2.4E-24 T 28-03-2018 SMD44_RS21665 4a1c9126d0e650d35cfb318e8543a246 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 6.7E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS21665 4a1c9126d0e650d35cfb318e8543a246 383 SUPERFAMILY SSF47203 234 375 4.03E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 Gene3D G3DSA:1.10.630.10 7 401 2.2E-72 T 28-03-2018 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 319 334 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 340 349 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 81 92 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 349 360 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 274 285 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 144 159 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 291 318 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 127 143 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 PRINTS PR00359 B-class P450 signature 193 215 1.7E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 SUPERFAMILY SSF48264 17 401 8.51E-88 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS42140 cff485aee14be33a67d78db9008d2c54 402 Pfam PF00067 Cytochrome P450 39 374 1.6E-22 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS27645 d8b39b41993d4b8085ffcad1bfaaa1bc 943 Gene3D G3DSA:1.20.120.330 224 777 0.0017 T 28-03-2018 SMD44_RS27645 d8b39b41993d4b8085ffcad1bfaaa1bc 943 Pfam PF04536 TPM domain 25 139 1.3E-17 T 28-03-2018 IPR007621 TPM domain SMD44_RS27645 d8b39b41993d4b8085ffcad1bfaaa1bc 943 Pfam PF04012 PspA/IM30 family 712 941 7.2E-33 T 28-03-2018 IPR007157 PspA/IM30 SMD44_RS33900 0f71eebae510e1098e34b50e34073a45 601 Gene3D G3DSA:3.40.50.1110 383 594 6.1E-20 T 28-03-2018 SMD44_RS33900 0f71eebae510e1098e34b50e34073a45 601 SUPERFAMILY SSF52266 388 594 2.0E-35 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS33900 0f71eebae510e1098e34b50e34073a45 601 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 393 586 2.8E-18 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 Gene3D G3DSA:3.40.50.620 139 283 7.1E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 PRINTS PR01438 Universal stress protein signature 2 20 7.1E-9 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 PRINTS PR01438 Universal stress protein signature 94 106 7.1E-9 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 PRINTS PR01438 Universal stress protein signature 112 134 7.1E-9 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 SUPERFAMILY SSF52402 144 281 7.2E-19 T 28-03-2018 SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 SUPERFAMILY SSF52402 7 135 2.01E-22 T 28-03-2018 SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 Pfam PF00582 Universal stress protein family 3 134 2.9E-18 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 Pfam PF00582 Universal stress protein family 144 281 2.3E-14 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS39130 1405340b9d8cb3a74f43c8655c02120e 283 Gene3D G3DSA:3.40.50.620 1 138 3.4E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 Gene3D G3DSA:3.40.50.10490 459 603 2.8E-46 T 28-03-2018 SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 Pfam PF01380 SIS domain 293 417 3.4E-29 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 Pfam PF01380 SIS domain 462 587 1.0E-20 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 SUPERFAMILY SSF53697 245 605 2.97E-99 T 28-03-2018 SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 Gene3D G3DSA:3.40.50.10490 240 458 3.4E-62 T 28-03-2018 SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 SUPERFAMILY SSF56235 2 234 2.49E-67 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 Gene3D G3DSA:3.60.20.10 2 239 3.8E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 Pfam PF13522 Glutamine amidotransferase domain 63 193 2.1E-20 T 28-03-2018 SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 37.511 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMD44_RS15010 88989d6b41ef0673642d8a8aa151e7f6 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 7.8E-225 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMD44_RS28750 6b65ca436eb2c4a0c6a0bbc6be486201 299 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 13 254 1.6E-83 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain SMD44_RS40745 90317bb2ad832ec1cd838335f06e96f1 476 SUPERFAMILY SSF53474 47 186 2.46E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS40745 90317bb2ad832ec1cd838335f06e96f1 476 SUPERFAMILY SSF53474 315 376 2.46E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS40745 90317bb2ad832ec1cd838335f06e96f1 476 SUPERFAMILY SSF53474 213 241 2.46E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS40745 90317bb2ad832ec1cd838335f06e96f1 476 Gene3D G3DSA:3.40.50.1820 47 463 7.2E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS03320 daf6416dd6df8fb3ce27bb87f38f7f05 466 SUPERFAMILY SSF88946 40 127 3.92E-9 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS03320 daf6416dd6df8fb3ce27bb87f38f7f05 466 Gene3D G3DSA:1.10.1740.10 36 114 1.4E-11 T 28-03-2018 SMD44_RS03320 daf6416dd6df8fb3ce27bb87f38f7f05 466 Pfam PF04542 Sigma-70 region 2 46 112 2.1E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS03320 daf6416dd6df8fb3ce27bb87f38f7f05 466 SUPERFAMILY SSF88659 142 188 1.7E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS03320 daf6416dd6df8fb3ce27bb87f38f7f05 466 Gene3D G3DSA:1.10.10.10 140 194 9.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12720 99292c1d20d6b895a73a4a04fe0535b8 137 Pfam PF03995 Peptidase inhibitor family I36 47 109 9.5E-9 T 28-03-2018 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 Pfam PF01029 NusB family 45 174 3.0E-24 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 481 498 2.1E-19 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 429 445 2.1E-19 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 280 294 2.1E-19 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 379 391 2.1E-19 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 313 323 2.1E-19 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 Gene3D G3DSA:1.10.940.10 40 185 1.1E-28 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 Gene3D G3DSA:3.40.50.150 289 500 6.3E-45 T 28-03-2018 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 378 389 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 SUPERFAMILY SSF53335 193 498 1.56E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 Pfam PF01189 16S rRNA methyltransferase RsmB/F 309 496 1.7E-45 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS07200 efd590b8eff4779675d926409ae3a840 500 SUPERFAMILY SSF48013 45 205 7.46E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD44_RS13585 d4ebddd68443053ac558664bcf5212b9 280 Gene3D G3DSA:1.10.3100.10 10 157 3.7E-13 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS13585 d4ebddd68443053ac558664bcf5212b9 280 SUPERFAMILY SSF47413 14 70 7.6E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS13585 d4ebddd68443053ac558664bcf5212b9 280 SMART SM00530 19 74 4.7E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS13585 d4ebddd68443053ac558664bcf5212b9 280 Pfam PF13560 Helix-turn-helix domain 16 71 1.0E-8 T 28-03-2018 SMD44_RS41655 c50a0a34bdb02a79bcbfb80fbcfbb512 131 SUPERFAMILY SSF54593 5 130 1.51E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS41655 c50a0a34bdb02a79bcbfb80fbcfbb512 131 Gene3D G3DSA:3.10.180.10 1 130 7.6E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS41655 c50a0a34bdb02a79bcbfb80fbcfbb512 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 126 7.4E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS26135 418cf6e27171c87cbc67a50444afaae5 500 SUPERFAMILY SSF103473 283 496 2.44E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26135 418cf6e27171c87cbc67a50444afaae5 500 SUPERFAMILY SSF103473 31 228 2.44E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26135 418cf6e27171c87cbc67a50444afaae5 500 Gene3D G3DSA:1.20.1250.20 36 232 2.9E-31 T 28-03-2018 SMD44_RS26135 418cf6e27171c87cbc67a50444afaae5 500 Pfam PF07690 Major Facilitator Superfamily 48 442 1.1E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS26135 418cf6e27171c87cbc67a50444afaae5 500 Gene3D G3DSA:1.20.1250.20 294 498 6.5E-19 T 28-03-2018 SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 Gene3D G3DSA:3.40.50.720 7 246 2.7E-64 T 28-03-2018 SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 1.0E-55 T 28-03-2018 SMD44_RS06460 76a726685dc436378813dc7d771d71aa 251 SUPERFAMILY SSF51735 7 246 1.77E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 54 137 9.7E-20 T 28-03-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 Gene3D G3DSA:3.20.70.20 49 704 2.6E-173 T 28-03-2018 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 PRINTS PR01183 Ribonucleotide reductase large chain signature 398 421 3.6E-15 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 PRINTS PR01183 Ribonucleotide reductase large chain signature 233 252 3.6E-15 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 PRINTS PR01183 Ribonucleotide reductase large chain signature 543 570 3.6E-15 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 PRINTS PR01183 Ribonucleotide reductase large chain signature 360 371 3.6E-15 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 PRINTS PR01183 Ribonucleotide reductase large chain signature 436 458 3.6E-15 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 PRINTS PR01183 Ribonucleotide reductase large chain signature 464 487 3.6E-15 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 SUPERFAMILY SSF51998 158 593 1.46E-131 T 28-03-2018 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 SUPERFAMILY SSF51998 627 701 1.46E-131 T 28-03-2018 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 Pfam PF02867 Ribonucleotide reductase, barrel domain 158 697 1.1E-148 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS31435 0ff1151913b6984f7549d11990afbd0c 963 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 96 707 1.7E-188 T 28-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS19740 f90e32d5d59dc81ccb732e9ec17a5050 113 Pfam PF06262 Zincin-like metallopeptidase 25 111 1.1E-33 T 28-03-2018 IPR010428 Zincin-like metallopeptidase SMD44_RS19740 f90e32d5d59dc81ccb732e9ec17a5050 113 SUPERFAMILY SSF55486 1 112 2.71E-39 T 28-03-2018 SMD44_RS41285 97c324839b9cd73d3e07284ec97a3871 136 Pfam PF01475 Ferric uptake regulator family 11 104 5.4E-25 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMD44_RS41285 97c324839b9cd73d3e07284ec97a3871 136 SUPERFAMILY SSF46785 3 133 2.68E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS41285 97c324839b9cd73d3e07284ec97a3871 136 Gene3D G3DSA:1.10.10.10 1 83 4.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05530 6a5d84fffe22e43769cd4be7764a48ef 213 SUPERFAMILY SSF46689 32 103 2.57E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05530 6a5d84fffe22e43769cd4be7764a48ef 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 6.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05530 6a5d84fffe22e43769cd4be7764a48ef 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 6.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05530 6a5d84fffe22e43769cd4be7764a48ef 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 79 2.3E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05530 6a5d84fffe22e43769cd4be7764a48ef 213 Gene3D G3DSA:1.10.10.60 1 77 4.2E-16 T 28-03-2018 SMD44_RS05530 6a5d84fffe22e43769cd4be7764a48ef 213 Gene3D G3DSA:1.10.357.10 78 207 9.3E-24 T 28-03-2018 SMD44_RS05530 6a5d84fffe22e43769cd4be7764a48ef 213 SUPERFAMILY SSF48498 101 206 5.06E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS09805 0cdd8d6d7bc6f313d46f0b66bdfb4e8f 200 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 194 8.7E-28 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS09805 0cdd8d6d7bc6f313d46f0b66bdfb4e8f 200 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 136 2.1E-16 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS09805 0cdd8d6d7bc6f313d46f0b66bdfb4e8f 200 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 14 194 1.6E-50 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 SMD44_RS09805 0cdd8d6d7bc6f313d46f0b66bdfb4e8f 200 Gene3D G3DSA:1.20.120.450 1 142 4.7E-17 T 28-03-2018 SMD44_RS09805 0cdd8d6d7bc6f313d46f0b66bdfb4e8f 200 SUPERFAMILY SSF109854 3 142 8.85E-21 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 SMART SM00382 30 232 1.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 SUPERFAMILY SSF52540 2 243 6.14E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 Pfam PF09383 NIL domain 259 331 2.7E-18 T 28-03-2018 IPR018449 NIL domain SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 Gene3D G3DSA:3.40.50.300 1 249 5.8E-74 T 28-03-2018 SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 Gene3D G3DSA:3.30.70.260 250 334 3.8E-19 T 28-03-2018 SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 SUPERFAMILY SSF55021 257 332 3.66E-16 T 28-03-2018 SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 Pfam PF00005 ABC transporter 22 175 5.6E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS07690 aa5c8d93fb70485ac232bf22aceb17a5 345 SMART SM00930 257 332 1.4E-19 T 28-03-2018 IPR018449 NIL domain SMD44_RS22465 a27c7e22c9583aca78c387c8e09e276f 755 Pfam PF13183 4Fe-4S dicluster domain 299 407 3.4E-14 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS22465 a27c7e22c9583aca78c387c8e09e276f 755 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 393 404 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS22465 a27c7e22c9583aca78c387c8e09e276f 755 Gene3D G3DSA:1.20.950.20 1 250 2.2E-41 T 28-03-2018 SMD44_RS22465 a27c7e22c9583aca78c387c8e09e276f 755 Pfam PF02754 Cysteine-rich domain 478 577 9.1E-14 T 28-03-2018 IPR004017 Cysteine-rich domain SMD44_RS22465 a27c7e22c9583aca78c387c8e09e276f 755 Pfam PF02754 Cysteine-rich domain 616 703 3.2E-19 T 28-03-2018 IPR004017 Cysteine-rich domain SMD44_RS22465 a27c7e22c9583aca78c387c8e09e276f 755 Gene3D G3DSA:1.10.1060.10 269 431 2.7E-31 T 28-03-2018 SMD44_RS22465 a27c7e22c9583aca78c387c8e09e276f 755 SUPERFAMILY SSF46548 376 421 1.92E-21 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD44_RS22465 a27c7e22c9583aca78c387c8e09e276f 755 SUPERFAMILY SSF46548 288 338 1.92E-21 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD44_RS24350 585a0ec9a73d0a838346121224543332 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 15 202 3.8E-33 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS24350 585a0ec9a73d0a838346121224543332 232 SMART SM00855 14 166 2.7E-16 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS24350 585a0ec9a73d0a838346121224543332 232 SUPERFAMILY SSF53254 13 204 3.74E-35 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS24350 585a0ec9a73d0a838346121224543332 232 Gene3D G3DSA:3.40.50.1240 9 210 2.3E-30 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 Gene3D G3DSA:3.40.50.150 246 435 3.6E-22 T 28-03-2018 SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 SUPERFAMILY SSF53335 256 410 1.4E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 263 377 2.2E-27 T 28-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 Gene3D G3DSA:3.30.950.10 135 233 7.0E-26 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 210 1.2E-16 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 PIRSF PIRSF036428 1 432 2.7E-105 T 28-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 Gene3D G3DSA:3.40.1010.10 1 134 8.9E-11 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 SUPERFAMILY SSF53790 6 223 7.85E-28 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09650 a56c1da966a867f520f5dd57c191e1ff 456 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 87 222 4.3E-37 T 28-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 78 402 3.8E-61 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 80 99 2.3E-8 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 341 356 2.3E-8 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 120 139 2.3E-8 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 384 403 2.3E-8 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 Gene3D G3DSA:1.20.1650.10 1 78 3.0E-22 T 28-03-2018 SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 SUPERFAMILY SSF53383 32 470 8.9E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 Gene3D G3DSA:3.90.1150.10 356 472 9.8E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS14975 73155348075219c44dde097bb0ae7368 480 Gene3D G3DSA:3.40.640.10 90 355 5.6E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS06900 263a0fecc05500b1647199b90aeb310d 264 Pfam PF00535 Glycosyl transferase family 2 25 187 2.6E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS06900 263a0fecc05500b1647199b90aeb310d 264 SUPERFAMILY SSF53448 25 235 3.24E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS06900 263a0fecc05500b1647199b90aeb310d 264 Gene3D G3DSA:3.90.550.10 8 250 6.0E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 Gene3D G3DSA:3.30.230.10 284 453 1.1E-24 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 TIGRFAM TIGR00416 sms: DNA repair protein RadA 9 450 1.2E-151 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 SUPERFAMILY SSF54211 293 453 2.09E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 Gene3D G3DSA:3.40.50.300 74 281 1.5E-41 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 SUPERFAMILY SSF52540 71 293 1.59E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 SMART SM00382 90 244 6.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 Pfam PF13541 Subunit ChlI of Mg-chelatase 369 429 1.7E-8 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 PRINTS PR01874 DNA repair protein radA signature 174 198 1.6E-85 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 PRINTS PR01874 DNA repair protein radA signature 82 110 1.6E-85 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 PRINTS PR01874 DNA repair protein radA signature 124 141 1.6E-85 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 PRINTS PR01874 DNA repair protein radA signature 322 345 1.6E-85 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 PRINTS PR01874 DNA repair protein radA signature 248 274 1.6E-85 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 PRINTS PR01874 DNA repair protein radA signature 16 40 1.6E-85 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 PRINTS PR01874 DNA repair protein radA signature 213 241 1.6E-85 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 Pfam PF13481 AAA domain 77 222 1.1E-14 T 28-03-2018 SMD44_RS23975 e3e4ed53277cd4e7bdc370bd2134a5a6 469 Hamap MF_01498 DNA repair protein RadA [radA]. 27 454 42.115 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SMD44_RS30405 70ff02e81bd270ca126edaf4a18e9503 325 Gene3D G3DSA:3.20.20.30 2 325 4.8E-64 T 28-03-2018 SMD44_RS30405 70ff02e81bd270ca126edaf4a18e9503 325 Pfam PF00296 Luciferase-like monooxygenase 18 250 1.8E-35 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS30405 70ff02e81bd270ca126edaf4a18e9503 325 SUPERFAMILY SSF51679 16 324 2.49E-55 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS08065 0da7bc2bbd6b783697a4a4fb436d0a3f 135 SUPERFAMILY SSF103196 5 129 9.77E-28 T 28-03-2018 SMD44_RS08065 0da7bc2bbd6b783697a4a4fb436d0a3f 135 SMART SM00960 9 100 6.3E-23 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS08065 0da7bc2bbd6b783697a4a4fb436d0a3f 135 Pfam PF03259 Roadblock/LC7 domain 9 100 2.6E-25 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS08065 0da7bc2bbd6b783697a4a4fb436d0a3f 135 Gene3D G3DSA:3.30.450.30 4 132 1.0E-34 T 28-03-2018 SMD44_RS19305 20963bd9101975a04ba56f5108a6997a 345 Pfam PF13377 Periplasmic binding protein-like domain 171 337 1.4E-32 T 28-03-2018 SMD44_RS19305 20963bd9101975a04ba56f5108a6997a 345 SUPERFAMILY SSF47413 3 62 1.13E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS19305 20963bd9101975a04ba56f5108a6997a 345 SUPERFAMILY SSF53822 64 339 1.2E-63 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS19305 20963bd9101975a04ba56f5108a6997a 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 1.8E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS19305 20963bd9101975a04ba56f5108a6997a 345 Gene3D G3DSA:3.40.50.2300 178 313 2.3E-38 T 28-03-2018 SMD44_RS19305 20963bd9101975a04ba56f5108a6997a 345 SMART SM00354 3 74 1.4E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS19305 20963bd9101975a04ba56f5108a6997a 345 Gene3D G3DSA:1.10.260.40 4 57 3.6E-20 T 28-03-2018 SMD44_RS19305 20963bd9101975a04ba56f5108a6997a 345 Gene3D G3DSA:3.40.50.2300 58 177 1.8E-31 T 28-03-2018 SMD44_RS24030 b7401b78ea60bd0ecd44109a5b8349fc 267 Gene3D G3DSA:3.40.50.300 7 262 3.1E-65 T 28-03-2018 SMD44_RS24030 b7401b78ea60bd0ecd44109a5b8349fc 267 Pfam PF00005 ABC transporter 36 181 1.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS24030 b7401b78ea60bd0ecd44109a5b8349fc 267 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS24030 b7401b78ea60bd0ecd44109a5b8349fc 267 SUPERFAMILY SSF52540 19 243 2.72E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS24030 b7401b78ea60bd0ecd44109a5b8349fc 267 SMART SM00382 45 238 6.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS41925 d6949d67f7793f3f0e06eb43c92270af 174 Gene3D G3DSA:3.40.50.300 1 174 1.1E-23 T 28-03-2018 SMD44_RS41925 d6949d67f7793f3f0e06eb43c92270af 174 SUPERFAMILY SSF52540 1 174 7.17E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS26685 e1b73ac6f95ba3e53fd4aec175393750 313 Gene3D G3DSA:3.20.20.70 11 280 1.2E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS26685 e1b73ac6f95ba3e53fd4aec175393750 313 Pfam PF03102 NeuB family 44 280 5.6E-81 T 28-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 SMD44_RS26685 e1b73ac6f95ba3e53fd4aec175393750 313 SUPERFAMILY SSF51569 13 293 1.47E-84 T 28-03-2018 SMD44_RS06490 7bac5f311f6d328de942a27541fce079 214 Pfam PF00857 Isochorismatase family 18 202 1.9E-25 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS06490 7bac5f311f6d328de942a27541fce079 214 SUPERFAMILY SSF52499 9 208 1.22E-37 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS06490 7bac5f311f6d328de942a27541fce079 214 Gene3D G3DSA:3.40.50.850 8 213 3.2E-32 T 28-03-2018 SMD44_RS03745 12ecabf8954a5798717d0af21534b304 182 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 58 106 6.0E-14 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS03745 12ecabf8954a5798717d0af21534b304 182 Gene3D G3DSA:1.20.1290.10 43 176 7.9E-24 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS03745 12ecabf8954a5798717d0af21534b304 182 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 117 1.4E-9 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS03745 12ecabf8954a5798717d0af21534b304 182 SUPERFAMILY SSF69118 1 172 4.05E-39 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS03745 12ecabf8954a5798717d0af21534b304 182 Gene3D G3DSA:1.20.5.810 10 42 1.7E-6 T 28-03-2018 SMD44_RS15580 c422c1eb102f5606b8b9474fcd0ba588 106 SUPERFAMILY SSF103481 6 104 1.44E-16 T 28-03-2018 SMD44_RS15580 c422c1eb102f5606b8b9474fcd0ba588 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 7.6E-26 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 230 6.1E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 1.7E-32 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 PIRSF PIRSF016578 4 119 3.8E-6 T 28-03-2018 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 PIRSF PIRSF016578 205 396 7.5E-11 T 28-03-2018 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 SUPERFAMILY SSF56645 9 253 7.85E-72 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 Gene3D G3DSA:1.10.540.10 6 124 2.6E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 Gene3D G3DSA:2.40.110.10 125 232 2.1E-31 T 28-03-2018 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 394 2.4E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 Gene3D G3DSA:1.20.140.10 233 400 1.5E-52 T 28-03-2018 SMD44_RS34175 fc486fdd4a65e14b555e2884f5e855b6 401 SUPERFAMILY SSF47203 244 397 2.09E-54 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS04065 96f49200e5b7332bebee203e948ecd85 410 SUPERFAMILY SSF53067 97 401 6.48E-33 T 28-03-2018 SMD44_RS04065 96f49200e5b7332bebee203e948ecd85 410 Gene3D G3DSA:3.30.420.40 223 408 7.7E-43 T 28-03-2018 SMD44_RS04065 96f49200e5b7332bebee203e948ecd85 410 Gene3D G3DSA:3.30.420.40 86 222 3.2E-22 T 28-03-2018 SMD44_RS04065 96f49200e5b7332bebee203e948ecd85 410 Pfam PF00480 ROK family 106 397 7.8E-34 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS04065 96f49200e5b7332bebee203e948ecd85 410 Gene3D G3DSA:1.10.10.10 14 85 1.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39805 4ea308ee1d8afaa37ad9f8a18c068c8b 179 SUPERFAMILY SSF52777 4 128 5.67E-21 T 28-03-2018 SMD44_RS39805 4ea308ee1d8afaa37ad9f8a18c068c8b 179 Pfam PF00668 Condensation domain 2 127 1.8E-12 T 28-03-2018 IPR001242 Condensation domain SMD44_RS33500 ae8e3c26693fa348f00d2268cbbb206d 259 Gene3D G3DSA:2.60.120.380 36 219 8.6E-6 T 28-03-2018 SMD44_RS16115 457b3c00a3cc904c5d3d514df01b4c5d 972 Pfam PF11380 Stealth protein CR2, conserved region 2 697 802 1.5E-45 T 28-03-2018 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 SMD44_RS16115 457b3c00a3cc904c5d3d514df01b4c5d 972 Pfam PF17101 Stealth protein CR1, conserved region 1 653 674 2.5E-10 T 28-03-2018 IPR031358 Stealth protein CR1, conserved region 1 SMD44_RS16115 457b3c00a3cc904c5d3d514df01b4c5d 972 Pfam PF13439 Glycosyltransferase Family 4 13 196 3.1E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS16115 457b3c00a3cc904c5d3d514df01b4c5d 972 Pfam PF17102 Stealth protein CR3, conserved region 3 848 895 3.3E-15 T 28-03-2018 IPR031357 Stealth protein CR3, conserved region 3 SMD44_RS16115 457b3c00a3cc904c5d3d514df01b4c5d 972 SUPERFAMILY SSF53756 90 384 2.67E-60 T 28-03-2018 SMD44_RS16115 457b3c00a3cc904c5d3d514df01b4c5d 972 SUPERFAMILY SSF53756 2 59 2.67E-60 T 28-03-2018 SMD44_RS16115 457b3c00a3cc904c5d3d514df01b4c5d 972 Pfam PF00534 Glycosyl transferases group 1 203 363 1.2E-35 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS16115 457b3c00a3cc904c5d3d514df01b4c5d 972 Gene3D G3DSA:3.40.50.2000 175 370 6.9E-41 T 28-03-2018 SMD44_RS41145 5f9d84fafd4e441dd3fa688cfdf70144 118 SUPERFAMILY SSF158560 1 110 1.44E-30 T 28-03-2018 SMD44_RS41145 5f9d84fafd4e441dd3fa688cfdf70144 118 Pfam PF06304 Protein of unknown function (DUF1048) 9 109 6.9E-30 T 28-03-2018 IPR008316 Uncharacterised conserved protein UCP029876 SMD44_RS41145 5f9d84fafd4e441dd3fa688cfdf70144 118 Gene3D G3DSA:1.10.1900.10 21 106 1.1E-27 T 28-03-2018 SMD44_RS26350 74b17139e9f6f6869ab9b6c1ddc80513 299 SUPERFAMILY SSF53335 30 298 5.78E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS26350 74b17139e9f6f6869ab9b6c1ddc80513 299 Pfam PF08241 Methyltransferase domain 92 190 1.6E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS26350 74b17139e9f6f6869ab9b6c1ddc80513 299 Gene3D G3DSA:3.40.50.150 80 214 1.4E-27 T 28-03-2018 SMD44_RS26350 74b17139e9f6f6869ab9b6c1ddc80513 299 Gene3D G3DSA:1.10.287.840 215 291 1.7E-16 T 28-03-2018 IPR023143 Mycolic acid cyclopropane synthase-like domain SMD44_RS26350 74b17139e9f6f6869ab9b6c1ddc80513 299 Gene3D G3DSA:1.10.287.840 36 79 8.4E-10 T 28-03-2018 IPR023143 Mycolic acid cyclopropane synthase-like domain SMD44_RS23895 f3f87410c74ab6d690d232f4b9832e0d 959 Gene3D G3DSA:3.40.50.300 250 283 0.0012 T 28-03-2018 SMD44_RS23895 f3f87410c74ab6d690d232f4b9832e0d 959 SUPERFAMILY SSF52540 266 414 3.06E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23895 f3f87410c74ab6d690d232f4b9832e0d 959 Gene3D G3DSA:3.40.50.300 284 803 0.0014 T 28-03-2018 SMD44_RS23895 f3f87410c74ab6d690d232f4b9832e0d 959 Pfam PF05729 NACHT domain 273 438 1.9E-29 T 28-03-2018 SMD44_RS00350 328d5af494187495c7fedf293b3fc3e1 140 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 130 8.6E-11 T 28-03-2018 IPR028973 PhnB-like SMD44_RS00350 328d5af494187495c7fedf293b3fc3e1 140 SUPERFAMILY SSF54593 2 132 2.14E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS00350 328d5af494187495c7fedf293b3fc3e1 140 Gene3D G3DSA:3.10.180.10 1 139 2.8E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS34385 f68d62c84491a740ee8ff9601989153f 89 Pfam PF05121 Gas vesicle protein K 3 86 6.5E-36 T 28-03-2018 IPR007805 Gas vesicle protein GvpK GO:0031412 SMD44_RS31875 6a7f792024b01c2384ad9320104571f3 418 Gene3D G3DSA:3.40.640.10 16 296 6.8E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS31875 6a7f792024b01c2384ad9320104571f3 418 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMD44_RS31875 6a7f792024b01c2384ad9320104571f3 418 Pfam PF00155 Aminotransferase class I and II 39 408 1.9E-48 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS31875 6a7f792024b01c2384ad9320104571f3 418 SUPERFAMILY SSF53383 38 413 7.48E-89 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS31875 6a7f792024b01c2384ad9320104571f3 418 Gene3D G3DSA:3.90.1150.10 297 415 2.0E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS18500 5e3a522e2285bda43830348c06f6ff07 196 Gene3D G3DSA:3.90.1570.10 10 191 1.9E-27 T 28-03-2018 SMD44_RS18500 5e3a522e2285bda43830348c06f6ff07 196 SUPERFAMILY SSF52980 33 169 3.49E-12 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS18500 5e3a522e2285bda43830348c06f6ff07 196 Pfam PF05685 Putative restriction endonuclease 22 188 2.1E-24 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS42335 3fd91710215ade8ef355c5524f8f7ba9 223 Gene3D G3DSA:1.10.10.60 81 194 3.7E-8 T 28-03-2018 SMD44_RS42335 3fd91710215ade8ef355c5524f8f7ba9 223 Gene3D G3DSA:1.10.10.60 40 80 5.8E-11 T 28-03-2018 SMD44_RS42335 3fd91710215ade8ef355c5524f8f7ba9 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 52 84 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS42335 3fd91710215ade8ef355c5524f8f7ba9 223 SUPERFAMILY SSF46689 38 98 8.25E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS16650 8bfda977c3beb5439de6ca4f50ed003b 305 SUPERFAMILY SSF55729 9 114 5.66E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS16650 8bfda977c3beb5439de6ca4f50ed003b 305 Gene3D G3DSA:3.40.630.30 1 121 2.2E-19 T 28-03-2018 SMD44_RS16650 8bfda977c3beb5439de6ca4f50ed003b 305 Pfam PF00583 Acetyltransferase (GNAT) family 26 113 1.6E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS16650 8bfda977c3beb5439de6ca4f50ed003b 305 Pfam PF00583 Acetyltransferase (GNAT) family 209 289 4.1E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS16650 8bfda977c3beb5439de6ca4f50ed003b 305 SUPERFAMILY SSF55729 136 297 4.15E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS16650 8bfda977c3beb5439de6ca4f50ed003b 305 Gene3D G3DSA:3.40.630.30 124 304 1.6E-15 T 28-03-2018 SMD44_RS08565 706456c743dfa335aa4db1467be2fd84 233 Gene3D G3DSA:3.20.20.70 1 232 4.6E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS08565 706456c743dfa335aa4db1467be2fd84 233 Pfam PF05853 beta-keto acid cleavage enzyme 2 230 2.8E-19 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 2.8E-9 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 2.8E-9 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 Pfam PF00117 Glutamine amidotransferase class-I 11 194 2.6E-54 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 9 192 2.0E-61 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 171 184 1.3E-13 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.3E-13 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 1.3E-13 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 Gene3D G3DSA:3.40.50.880 7 198 6.3E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00097 Anthranilate synthase component II signature 81 92 6.3E-34 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00097 Anthranilate synthase component II signature 171 184 6.3E-34 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00097 Anthranilate synthase component II signature 126 138 6.3E-34 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00097 Anthranilate synthase component II signature 106 114 6.3E-34 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00097 Anthranilate synthase component II signature 9 23 6.3E-34 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 PRINTS PR00097 Anthranilate synthase component II signature 53 62 6.3E-34 T 28-03-2018 SMD44_RS21430 80a2c44630701c173ccf61212368c1ef 216 SUPERFAMILY SSF52317 8 195 8.14E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS20125 ee22f2efa33ef2946c35494c2f0ea786 159 Pfam PF00027 Cyclic nucleotide-binding domain 22 103 9.7E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS20125 ee22f2efa33ef2946c35494c2f0ea786 159 SMART SM00100 5 125 1.5E-7 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS20125 ee22f2efa33ef2946c35494c2f0ea786 159 SUPERFAMILY SSF51206 12 103 6.02E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SMD44_RS20125 ee22f2efa33ef2946c35494c2f0ea786 159 Gene3D G3DSA:2.60.120.10 8 108 2.2E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS18685 75e1afb1d480b90378dc8a1f0e15110f 312 Gene3D G3DSA:2.60.120.260 244 306 0.022 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS28665 27ffe188fd24809724abb590bcdb590e 138 Pfam PF05331 Protein of unknown function (DUF742) 16 138 4.6E-38 T 28-03-2018 IPR007995 Protein of unknown function DUF742 SMD44_RS33775 8bc0d3df7d9ee8595d2f086d941b71c0 253 Gene3D G3DSA:3.30.450.40 6 180 2.1E-11 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS33775 8bc0d3df7d9ee8595d2f086d941b71c0 253 SUPERFAMILY SSF55781 30 167 1.64E-11 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS33775 8bc0d3df7d9ee8595d2f086d941b71c0 253 PIRSF PIRSF036625 12 244 8.4E-34 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS33775 8bc0d3df7d9ee8595d2f086d941b71c0 253 Pfam PF03861 ANTAR domain 190 234 2.7E-9 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS33775 8bc0d3df7d9ee8595d2f086d941b71c0 253 SMART SM01012 175 234 1.7E-10 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS33775 8bc0d3df7d9ee8595d2f086d941b71c0 253 Gene3D G3DSA:1.10.10.10 189 236 4.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18040 e9625af1c6071c692d48671ad9db9020 456 SUPERFAMILY SSF103473 32 449 1.31E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS18040 e9625af1c6071c692d48671ad9db9020 456 Pfam PF07690 Major Facilitator Superfamily 294 447 2.1E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS18040 e9625af1c6071c692d48671ad9db9020 456 Pfam PF07690 Major Facilitator Superfamily 54 278 5.1E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS18040 e9625af1c6071c692d48671ad9db9020 456 Gene3D G3DSA:1.20.1250.20 256 453 3.0E-20 T 28-03-2018 SMD44_RS18040 e9625af1c6071c692d48671ad9db9020 456 Gene3D G3DSA:1.20.1250.20 37 232 1.9E-27 T 28-03-2018 SMD44_RS09960 f85d2f5fbbc67bf3b942c2e4ef7a7214 332 Gene3D G3DSA:3.30.60.70 124 164 4.1E-18 T 28-03-2018 SMD44_RS09960 f85d2f5fbbc67bf3b942c2e4ef7a7214 332 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 14 331 7.4E-152 T 28-03-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 SMD44_RS09960 f85d2f5fbbc67bf3b942c2e4ef7a7214 332 SUPERFAMILY SSF51161 83 311 2.77E-39 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS09960 f85d2f5fbbc67bf3b942c2e4ef7a7214 332 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 246 278 4.7E-14 T 28-03-2018 IPR001451 Hexapeptide repeat SMD44_RS09960 f85d2f5fbbc67bf3b942c2e4ef7a7214 332 Gene3D G3DSA:2.160.10.10 165 296 4.3E-16 T 28-03-2018 SMD44_RS09960 f85d2f5fbbc67bf3b942c2e4ef7a7214 332 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 12 329 43.77 T 28-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 SMD44_RS09960 f85d2f5fbbc67bf3b942c2e4ef7a7214 332 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 124 164 4.7E-18 T 28-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 SMD44_RS14425 1b1e763b64b39aa83169950d43479774 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 138 8.8E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS14425 1b1e763b64b39aa83169950d43479774 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 8.8E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS14425 1b1e763b64b39aa83169950d43479774 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 154 174 8.8E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS14425 1b1e763b64b39aa83169950d43479774 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 118 8.8E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS14425 1b1e763b64b39aa83169950d43479774 184 SMART SM00347 59 162 2.3E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS14425 1b1e763b64b39aa83169950d43479774 184 SUPERFAMILY SSF46785 32 176 4.47E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14425 1b1e763b64b39aa83169950d43479774 184 Pfam PF12802 MarR family 64 126 3.2E-14 T 28-03-2018 SMD44_RS14425 1b1e763b64b39aa83169950d43479774 184 Gene3D G3DSA:1.10.10.10 4 177 1.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12070 e0b09ad3f683b78c4c2e0edb5c009847 256 SMART SM00943 42 224 1.1E-36 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS12070 e0b09ad3f683b78c4c2e0edb5c009847 256 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 43 217 1.2E-26 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 228 298 1.4E-11 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 300 6.4E-96 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 Gene3D G3DSA:3.40.190.10 2 108 5.2E-35 T 28-03-2018 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 300 33.112 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 Gene3D G3DSA:3.30.160.40 223 307 2.2E-16 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 214 7.9E-61 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 SUPERFAMILY SSF53850 6 218 2.24E-64 T 28-03-2018 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 5.2E-25 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 5.2E-25 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 PRINTS PR00151 Porphobilinogen deaminase signature 232 249 5.2E-25 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 PRINTS PR00151 Porphobilinogen deaminase signature 126 143 5.2E-25 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 PRINTS PR00151 Porphobilinogen deaminase signature 145 162 5.2E-25 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 SUPERFAMILY SSF54782 223 309 8.24E-19 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 PIRSF PIRSF001438 1 311 2.9E-96 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 233 249 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS03095 d3f79715286b0adb4466026f7ea20a17 311 Gene3D G3DSA:3.40.190.10 109 201 2.8E-30 T 28-03-2018 SMD44_RS30270 f31027eba5e302dfb9a3833daee5262f 232 Pfam PF01983 Guanylyl transferase CofC like 5 143 5.1E-8 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMD44_RS30270 f31027eba5e302dfb9a3833daee5262f 232 Gene3D G3DSA:3.90.550.10 1 175 1.1E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS30270 f31027eba5e302dfb9a3833daee5262f 232 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 4 221 1.2E-45 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMD44_RS30270 f31027eba5e302dfb9a3833daee5262f 232 SUPERFAMILY SSF53448 3 222 4.51E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS30270 f31027eba5e302dfb9a3833daee5262f 232 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 3 228 21.751 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 SUPERFAMILY SSF54292 262 361 6.55E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 PRINTS PR00409 Phthalate dioxygenase reductase family signature 188 197 1.3E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 PRINTS PR00409 Phthalate dioxygenase reductase family signature 163 182 1.3E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 PRINTS PR00409 Phthalate dioxygenase reductase family signature 240 248 1.3E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 PRINTS PR00409 Phthalate dioxygenase reductase family signature 141 155 1.3E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 PRINTS PR00409 Phthalate dioxygenase reductase family signature 78 88 1.3E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 PRINTS PR00409 Phthalate dioxygenase reductase family signature 127 141 1.3E-26 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 SUPERFAMILY SSF52343 149 272 6.02E-25 T 28-03-2018 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 Gene3D G3DSA:3.10.20.30 268 363 1.4E-19 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 Pfam PF00175 Oxidoreductase NAD-binding domain 164 253 2.5E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 SUPERFAMILY SSF63380 52 151 8.72E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 286 354 2.0E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 Gene3D G3DSA:3.40.50.80 156 267 1.3E-18 T 28-03-2018 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 314 322 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD44_RS11825 c5c1b2fb92db6150d467104cde77a812 363 Gene3D G3DSA:2.40.30.10 46 152 1.7E-16 T 28-03-2018 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 92 115 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 Pfam PF00732 GMC oxidoreductase 17 316 4.3E-77 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 SUPERFAMILY SSF51905 467 524 5.44E-79 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 SUPERFAMILY SSF51905 14 309 5.44E-79 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 Pfam PF05199 GMC oxidoreductase 382 518 3.0E-36 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 Gene3D G3DSA:4.10.450.10 49 114 1.4E-24 T 28-03-2018 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 Gene3D G3DSA:3.30.560.10 115 480 4.2E-95 T 28-03-2018 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 SUPERFAMILY SSF54373 312 468 1.08E-32 T 28-03-2018 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 275 289 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 PIRSF PIRSF000137 361 526 5.6E-41 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS13525 bc2269d7608da0057ce81276bb5ad066 526 PIRSF PIRSF000137 4 362 2.2E-97 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS16205 253e4d671b7264f825f7e551a700caa3 259 Gene3D G3DSA:3.40.1410.10 82 254 6.9E-32 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS16205 253e4d671b7264f825f7e551a700caa3 259 SUPERFAMILY SSF64288 100 256 2.17E-28 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS16205 253e4d671b7264f825f7e551a700caa3 259 SMART SM00866 110 251 7.1E-16 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS16205 253e4d671b7264f825f7e551a700caa3 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 3.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS16205 253e4d671b7264f825f7e551a700caa3 259 SMART SM00345 20 79 4.9E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS16205 253e4d671b7264f825f7e551a700caa3 259 Gene3D G3DSA:1.10.10.10 1 81 4.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16205 253e4d671b7264f825f7e551a700caa3 259 Pfam PF07702 UTRA domain 112 248 3.5E-21 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS16205 253e4d671b7264f825f7e551a700caa3 259 SUPERFAMILY SSF46785 11 83 1.11E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20640 7c1abcc1f5a1bada3bac6514cd1e48cc 165 Pfam PF02627 Carboxymuconolactone decarboxylase family 26 106 1.3E-20 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS20640 7c1abcc1f5a1bada3bac6514cd1e48cc 165 Gene3D G3DSA:1.20.1290.10 16 164 1.3E-34 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS20640 7c1abcc1f5a1bada3bac6514cd1e48cc 165 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 91 6.5E-20 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS20640 7c1abcc1f5a1bada3bac6514cd1e48cc 165 SUPERFAMILY SSF69118 20 154 4.58E-40 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS08550 01801a5851bc46d170276434e0d69707 948 SUPERFAMILY SSF56235 123 328 3.6E-93 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS08550 01801a5851bc46d170276434e0d69707 948 SUPERFAMILY SSF56235 408 867 3.6E-93 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS08550 01801a5851bc46d170276434e0d69707 948 Gene3D G3DSA:1.10.439.10 120 293 2.7E-32 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 SMD44_RS08550 01801a5851bc46d170276434e0d69707 948 Gene3D G3DSA:1.10.287.150 294 336 4.0E-19 T 28-03-2018 SMD44_RS08550 01801a5851bc46d170276434e0d69707 948 Pfam PF01804 Penicillin amidase 124 935 1.5E-123 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 SMD44_RS08550 01801a5851bc46d170276434e0d69707 948 Gene3D G3DSA:3.60.20.10 416 947 2.0E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 Gene3D G3DSA:3.40.190.10 85 179 3.7E-17 T 28-03-2018 SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 Pfam PF03466 LysR substrate binding domain 88 289 1.3E-20 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 SUPERFAMILY SSF46785 2 81 5.99E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 Gene3D G3DSA:3.40.190.10 180 264 3.8E-6 T 28-03-2018 SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 SUPERFAMILY SSF53850 93 289 8.87E-19 T 28-03-2018 SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.9E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS16640 5ed08470dcabd2077ed4383859c90444 295 Gene3D G3DSA:1.10.10.10 1 84 2.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10180 d8f3c4d761c6261d1c532011df02d88a 286 SUPERFAMILY SSF47413 29 81 6.22E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS10180 d8f3c4d761c6261d1c532011df02d88a 286 Gene3D G3DSA:1.10.260.40 2 97 8.1E-18 T 28-03-2018 SMD44_RS10180 d8f3c4d761c6261d1c532011df02d88a 286 Pfam PF13560 Helix-turn-helix domain 5 84 1.6E-18 T 28-03-2018 SMD44_RS10180 d8f3c4d761c6261d1c532011df02d88a 286 SMART SM00530 9 81 2.1E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 624 40.61 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 SMART SM00861 316 480 6.2E-50 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 Gene3D G3DSA:3.40.50.920 489 630 3.9E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 SUPERFAMILY SSF52518 311 478 2.76E-50 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 Pfam PF02780 Transketolase, C-terminal domain 504 615 2.7E-28 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 4.3E-110 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 Gene3D G3DSA:3.40.50.970 309 482 4.7E-37 T 28-03-2018 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 623 2.3E-182 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 SUPERFAMILY SSF52922 502 622 1.44E-26 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 Pfam PF02779 Transketolase, pyrimidine binding domain 316 478 2.5E-35 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 Gene3D G3DSA:3.40.50.970 1 308 3.2E-79 T 28-03-2018 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS35545 139460c492e803e9b5412b9a4733b2bc 654 SUPERFAMILY SSF52518 2 346 4.18E-71 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS38020 ef91abcd35b4273db20b76d3638660cc 1156 Gene3D G3DSA:3.40.50.1460 928 1150 1.4E-18 T 28-03-2018 SMD44_RS38020 ef91abcd35b4273db20b76d3638660cc 1156 Pfam PF12770 CHAT domain 842 1147 8.3E-43 T 28-03-2018 IPR024983 CHAT domain SMD44_RS13715 81bd3002bb3601f2af26d07a89c5eb01 117 Gene3D G3DSA:3.40.140.10 5 113 4.2E-10 T 28-03-2018 SMD44_RS13715 81bd3002bb3601f2af26d07a89c5eb01 117 SUPERFAMILY SSF53927 10 110 9.03E-10 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMD44_RS15405 c6af0d38d5c3e8f4f41d0142643e0766 373 Pfam PF01266 FAD dependent oxidoreductase 2 369 4.1E-48 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS15405 c6af0d38d5c3e8f4f41d0142643e0766 373 Gene3D G3DSA:3.30.9.10 164 330 8.2E-22 T 28-03-2018 SMD44_RS15405 c6af0d38d5c3e8f4f41d0142643e0766 373 Gene3D G3DSA:3.50.50.60 1 74 1.7E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS15405 c6af0d38d5c3e8f4f41d0142643e0766 373 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 365 8.3E-103 T 28-03-2018 IPR017741 FAD-dependent oxidoreductase, HpnW SMD44_RS15405 c6af0d38d5c3e8f4f41d0142643e0766 373 SUPERFAMILY SSF51905 331 371 4.4E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS15405 c6af0d38d5c3e8f4f41d0142643e0766 373 SUPERFAMILY SSF51905 2 212 4.4E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS15405 c6af0d38d5c3e8f4f41d0142643e0766 373 Gene3D G3DSA:3.30.9.10 81 163 0.033 T 28-03-2018 SMD44_RS25995 6a532266d5aefd27ed2eb12f150c98af 356 SUPERFAMILY SSF52540 52 334 2.0E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25995 6a532266d5aefd27ed2eb12f150c98af 356 Pfam PF07728 AAA domain (dynein-related subfamily) 74 212 5.3E-36 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SMD44_RS25995 6a532266d5aefd27ed2eb12f150c98af 356 Gene3D G3DSA:3.40.50.300 49 242 5.2E-16 T 28-03-2018 SMD44_RS05800 809c076053a89206de17ca1b1f69f166 303 Pfam PF03466 LysR substrate binding domain 91 297 1.7E-42 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS05800 809c076053a89206de17ca1b1f69f166 303 Gene3D G3DSA:1.10.10.10 1 87 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05800 809c076053a89206de17ca1b1f69f166 303 Gene3D G3DSA:3.40.190.10 184 273 3.3E-22 T 28-03-2018 SMD44_RS05800 809c076053a89206de17ca1b1f69f166 303 Gene3D G3DSA:3.40.190.10 90 183 1.4E-21 T 28-03-2018 SMD44_RS05800 809c076053a89206de17ca1b1f69f166 303 SUPERFAMILY SSF53850 92 301 8.36E-41 T 28-03-2018 SMD44_RS05800 809c076053a89206de17ca1b1f69f166 303 SUPERFAMILY SSF46785 1 111 4.17E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05800 809c076053a89206de17ca1b1f69f166 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 5.9E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS06815 a62ac7bed3ad5006b95ccdc636e8e166 255 PIRSF PIRSF029755 1 255 4.7E-116 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 SMD44_RS06815 a62ac7bed3ad5006b95ccdc636e8e166 255 Pfam PF07286 Protein of unknown function (DUF1445) 104 246 1.3E-62 T 28-03-2018 IPR009906 D-glutamate cyclase SMD44_RS06815 a62ac7bed3ad5006b95ccdc636e8e166 255 Gene3D G3DSA:3.40.1640.10 1 154 2.9E-63 T 28-03-2018 SMD44_RS06815 a62ac7bed3ad5006b95ccdc636e8e166 255 Gene3D G3DSA:3.40.1640.10 191 255 6.2E-10 T 28-03-2018 SMD44_RS06815 a62ac7bed3ad5006b95ccdc636e8e166 255 Hamap MF_01830 UPF0317 protein . 2 254 52.414 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 SMD44_RS06815 a62ac7bed3ad5006b95ccdc636e8e166 255 SUPERFAMILY SSF160920 1 247 3.4E-109 T 28-03-2018 SMD44_RS01525 d9c79a911825a5d66651732fbbef0366 218 SUPERFAMILY SSF55797 93 215 1.1E-20 T 28-03-2018 IPR014044 CAP domain SMD44_RS01525 d9c79a911825a5d66651732fbbef0366 218 Gene3D G3DSA:3.40.33.10 87 215 7.7E-18 T 28-03-2018 IPR014044 CAP domain SMD44_RS01525 d9c79a911825a5d66651732fbbef0366 218 Pfam PF00188 Cysteine-rich secretory protein family 101 214 7.6E-19 T 28-03-2018 IPR014044 CAP domain SMD44_RS31265 ed3e71f9c90a424c241a62468f142d2f 306 SMART SM00062 70 293 5.8E-55 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS31265 ed3e71f9c90a424c241a62468f142d2f 306 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 93 106 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SMD44_RS31265 ed3e71f9c90a424c241a62468f142d2f 306 Gene3D G3DSA:3.40.190.10 173 255 9.2E-24 T 28-03-2018 SMD44_RS31265 ed3e71f9c90a424c241a62468f142d2f 306 Gene3D G3DSA:3.40.190.10 60 172 1.6E-26 T 28-03-2018 SMD44_RS31265 ed3e71f9c90a424c241a62468f142d2f 306 SUPERFAMILY SSF53850 60 287 5.76E-59 T 28-03-2018 SMD44_RS31265 ed3e71f9c90a424c241a62468f142d2f 306 SUPERFAMILY SSF53850 5 22 5.76E-59 T 28-03-2018 SMD44_RS31265 ed3e71f9c90a424c241a62468f142d2f 306 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 72 287 1.5E-49 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS35540 d11dd9a8824947f6d1a912d650c3c801 388 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 20 371 33.368 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS35540 d11dd9a8824947f6d1a912d650c3c801 388 Gene3D G3DSA:3.20.20.120 27 162 2.1E-16 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS35540 d11dd9a8824947f6d1a912d650c3c801 388 SUPERFAMILY SSF56014 279 363 7.19E-11 T 28-03-2018 SMD44_RS35540 d11dd9a8824947f6d1a912d650c3c801 388 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 22 364 1.4E-126 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS35540 d11dd9a8824947f6d1a912d650c3c801 388 Pfam PF04551 GcpE protein 26 365 2.7E-132 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS35540 d11dd9a8824947f6d1a912d650c3c801 388 PIRSF PIRSF004640 15 376 4.0E-144 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD44_RS35540 d11dd9a8824947f6d1a912d650c3c801 388 SUPERFAMILY SSF51717 49 223 1.8E-8 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD44_RS35540 d11dd9a8824947f6d1a912d650c3c801 388 Gene3D G3DSA:3.20.20.120 163 384 0.055 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS33860 c97c543729b5a97975603975b930dee1 596 SUPERFAMILY SSF52540 341 587 1.7E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS33860 c97c543729b5a97975603975b930dee1 596 Pfam PF00005 ABC transporter 369 516 2.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS33860 c97c543729b5a97975603975b930dee1 596 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS33860 c97c543729b5a97975603975b930dee1 596 SUPERFAMILY SSF90123 23 328 1.31E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS33860 c97c543729b5a97975603975b930dee1 596 Pfam PF00664 ABC transporter transmembrane region 37 304 1.9E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS33860 c97c543729b5a97975603975b930dee1 596 Gene3D G3DSA:1.20.1560.10 18 337 3.0E-55 T 28-03-2018 SMD44_RS33860 c97c543729b5a97975603975b930dee1 596 SMART SM00382 376 562 2.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS33860 c97c543729b5a97975603975b930dee1 596 Gene3D G3DSA:3.40.50.300 338 588 6.1E-72 T 28-03-2018 SMD44_RS03195 aa069dd3cc81a62039dd8560f9c61655 394 Gene3D G3DSA:3.30.200.20 109 172 1.8E-4 T 28-03-2018 SMD44_RS03195 aa069dd3cc81a62039dd8560f9c61655 394 Gene3D G3DSA:1.10.510.10 225 327 9.6E-12 T 28-03-2018 SMD44_RS03195 aa069dd3cc81a62039dd8560f9c61655 394 Pfam PF01636 Phosphotransferase enzyme family 105 322 5.6E-18 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS03195 aa069dd3cc81a62039dd8560f9c61655 394 SUPERFAMILY SSF56112 78 306 6.58E-25 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 Gene3D G3DSA:2.40.30.10 202 291 5.9E-16 T 28-03-2018 SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 Pfam PF08022 FAD-binding domain 219 300 1.2E-4 T 28-03-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 Gene3D G3DSA:3.40.50.80 292 420 5.5E-21 T 28-03-2018 SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 Pfam PF00175 Oxidoreductase NAD-binding domain 313 404 1.7E-8 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 SUPERFAMILY SSF52343 292 421 1.7E-26 T 28-03-2018 SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 PRINTS PR00409 Phthalate dioxygenase reductase family signature 312 331 4.0E-7 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 PRINTS PR00409 Phthalate dioxygenase reductase family signature 391 399 4.0E-7 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 SUPERFAMILY SSF63380 206 301 5.38E-15 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS00940 48a2debddba340d344f8371b24a051d1 427 Pfam PF01794 Ferric reductase like transmembrane component 39 160 1.5E-15 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain SMD44_RS21055 aabb032ca58a396becb9aec4c3ed06ce 252 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 182 1.8E-27 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21055 aabb032ca58a396becb9aec4c3ed06ce 252 SUPERFAMILY SSF88659 123 184 6.11E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21055 aabb032ca58a396becb9aec4c3ed06ce 252 Pfam PF04542 Sigma-70 region 2 30 96 4.2E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21055 aabb032ca58a396becb9aec4c3ed06ce 252 Pfam PF08281 Sigma-70, region 4 129 181 1.3E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21055 aabb032ca58a396becb9aec4c3ed06ce 252 SUPERFAMILY SSF88946 6 114 3.77E-30 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21055 aabb032ca58a396becb9aec4c3ed06ce 252 Gene3D G3DSA:1.10.1740.10 6 98 3.8E-26 T 28-03-2018 SMD44_RS21055 aabb032ca58a396becb9aec4c3ed06ce 252 Gene3D G3DSA:1.10.10.10 99 188 1.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04355 5c90ece42975a761f2617d592f7141d2 956 Gene3D G3DSA:2.60.40.10 402 568 3.3E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS04355 5c90ece42975a761f2617d592f7141d2 956 SUPERFAMILY SSF49265 423 459 3.39E-10 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS04355 5c90ece42975a761f2617d592f7141d2 956 SUPERFAMILY SSF49265 489 554 3.39E-10 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS04355 5c90ece42975a761f2617d592f7141d2 956 Gene3D G3DSA:2.60.40.10 618 731 0.0035 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS12405 5f46ada6c874dc760287f6c3227d077e 521 Gene3D G3DSA:3.40.50.620 190 493 1.1E-7 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS12405 5f46ada6c874dc760287f6c3227d077e 521 SUPERFAMILY SSF52402 193 345 2.27E-10 T 28-03-2018 SMD44_RS12405 5f46ada6c874dc760287f6c3227d077e 521 SUPERFAMILY SSF52402 383 447 2.27E-10 T 28-03-2018 SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 Pfam PF07729 FCD domain 101 221 1.3E-23 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 SUPERFAMILY SSF46785 8 79 3.61E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 1.6E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 Gene3D G3DSA:1.10.10.10 4 74 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 Gene3D G3DSA:1.20.120.530 75 236 1.2E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 SMART SM00345 16 75 9.8E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 SMART SM00895 101 223 2.3E-20 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 1.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 1.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS01590 fbd8e2dfb778bf9caf122786e0d14ac1 236 SUPERFAMILY SSF48008 99 231 4.18E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 SMART SM00342 225 308 7.1E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 Gene3D G3DSA:2.60.120.280 12 189 5.7E-17 T 28-03-2018 SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 Pfam PF12833 Helix-turn-helix domain 236 309 1.4E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 Gene3D G3DSA:1.10.10.60 265 313 9.5E-14 T 28-03-2018 SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 Gene3D G3DSA:1.10.10.60 203 264 2.7E-5 T 28-03-2018 SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 SUPERFAMILY SSF46689 261 310 3.72E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 SUPERFAMILY SSF46689 209 258 1.39E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 Pfam PF12852 Cupin 2 188 6.5E-47 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 292 308 1.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS29625 97fdd9cc179d7197dd087d0b87a58bb6 313 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 277 292 1.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS12880 46ffdbb413a916de1be57c7eedeb6b5a 252 SUPERFAMILY SSF53335 42 230 4.14E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS12880 46ffdbb413a916de1be57c7eedeb6b5a 252 Gene3D G3DSA:3.40.50.150 17 236 5.3E-33 T 28-03-2018 SMD44_RS12880 46ffdbb413a916de1be57c7eedeb6b5a 252 Pfam PF08241 Methyltransferase domain 59 151 2.4E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 84 301 6.3E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 Gene3D G3DSA:1.10.10.10 232 307 3.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 111 124 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 Pfam PF04545 Sigma-70, region 4 252 300 2.3E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 82 302 5.7E-88 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 Pfam PF04542 Sigma-70 region 2 87 156 1.6E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 Pfam PF04539 Sigma-70 region 3 166 229 7.9E-15 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 PRINTS PR00046 Major sigma-70 factor signature 111 124 9.3E-8 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 PRINTS PR00046 Major sigma-70 factor signature 273 288 9.3E-8 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 PRINTS PR00046 Major sigma-70 factor signature 256 268 9.3E-8 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 SUPERFAMILY SSF88946 61 157 2.75E-30 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 Gene3D G3DSA:1.10.601.10 59 156 1.3E-24 T 28-03-2018 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 Gene3D G3DSA:1.10.10.10 157 209 4.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 SUPERFAMILY SSF88659 160 233 1.8E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS20255 e5584c46715355b195629feff0aeb771 307 SUPERFAMILY SSF88659 238 302 1.57E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS08690 672a87eccd1894f2e72a0d2db2b0b599 462 Gene3D G3DSA:3.40.50.1980 250 348 2.6E-4 T 28-03-2018 SMD44_RS08690 672a87eccd1894f2e72a0d2db2b0b599 462 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 272 413 1.5E-5 T 28-03-2018 SMD44_RS02310 e4b1cd6cc7a8e1cd3685b0d1274540dc 267 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 101 4.4E-13 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMD44_RS02310 e4b1cd6cc7a8e1cd3685b0d1274540dc 267 SUPERFAMILY SSF51735 3 149 1.72E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02310 e4b1cd6cc7a8e1cd3685b0d1274540dc 267 Gene3D G3DSA:3.40.50.720 1 166 6.7E-13 T 28-03-2018 SMD44_RS02310 e4b1cd6cc7a8e1cd3685b0d1274540dc 267 Gene3D G3DSA:1.10.3730.10 167 257 1.3E-6 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 620 634 3.6E-5 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 399 3.6E-5 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 SUPERFAMILY SSF51395 4 363 8.74E-109 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 329 8.2E-81 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 SUPERFAMILY SSF51971 334 523 2.83E-42 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 Gene3D G3DSA:3.40.50.720 371 482 6.0E-23 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 Gene3D G3DSA:3.50.50.60 483 626 2.5E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 378 397 2.0E-16 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 460 478 2.0E-16 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 619 635 2.0E-16 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 500 518 2.0E-16 T 28-03-2018 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 Gene3D G3DSA:3.20.20.70 3 370 1.4E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 377 642 8.0E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 SUPERFAMILY SSF51905 463 521 2.88E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03880 b1ec94b9f95dc9fca268718f6a722e4a 673 SUPERFAMILY SSF51905 557 651 2.88E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00055 1bf9f3303adbb4770554e28393cab788 160 Gene3D G3DSA:1.20.1170.10 4 150 1.4E-5 T 28-03-2018 SMD44_RS27120 dba07b194d2fd33df43f37cb96eaae1d 346 SMART SM00382 29 218 6.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS27120 dba07b194d2fd33df43f37cb96eaae1d 346 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 1.5E-109 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD44_RS27120 dba07b194d2fd33df43f37cb96eaae1d 346 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 1.4E-8 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 SMD44_RS27120 dba07b194d2fd33df43f37cb96eaae1d 346 Pfam PF00005 ABC transporter 20 163 1.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS27120 dba07b194d2fd33df43f37cb96eaae1d 346 Gene3D G3DSA:3.40.50.300 1 344 1.1E-67 T 28-03-2018 SMD44_RS27120 dba07b194d2fd33df43f37cb96eaae1d 346 SUPERFAMILY SSF52540 3 236 7.88E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27120 dba07b194d2fd33df43f37cb96eaae1d 346 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS22135 ead5431915b173095f0af9dd7517fc6e 287 SUPERFAMILY SSF51679 1 259 2.36E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS22135 ead5431915b173095f0af9dd7517fc6e 287 Pfam PF00296 Luciferase-like monooxygenase 2 178 3.7E-39 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS22135 ead5431915b173095f0af9dd7517fc6e 287 Gene3D G3DSA:3.20.20.30 1 286 9.6E-57 T 28-03-2018 SMD44_RS29140 4cc3b387690787f0b9b4f15533194ea0 566 SUPERFAMILY SSF51703 8 560 1.2E-191 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS29140 4cc3b387690787f0b9b4f15533194ea0 566 Pfam PF01642 Methylmalonyl-CoA mutase 29 558 3.3E-212 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS29140 4cc3b387690787f0b9b4f15533194ea0 566 Gene3D G3DSA:3.20.20.240 27 560 8.8E-210 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS29140 4cc3b387690787f0b9b4f15533194ea0 566 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 564 3.7E-200 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 Gene3D G3DSA:3.30.980.10 562 723 1.1E-34 T 28-03-2018 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 5.2E-13 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 SUPERFAMILY SSF55681 3 248 5.8E-87 T 28-03-2018 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 SUPERFAMILY SSF55186 561 717 1.96E-38 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 2.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 2.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 2.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 2.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 2.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 Pfam PF01411 tRNA synthetases class II (A) 5 564 3.3E-181 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 SUPERFAMILY SSF101353 249 442 1.09E-53 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 884 150.237 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 SMART SM00863 662 706 1.3E-15 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 SUPERFAMILY SSF50447 462 561 1.17E-15 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 Gene3D G3DSA:3.30.930.10 1 245 1.7E-95 T 28-03-2018 SMD44_RS39970 dfaed9cab87bf17ea8f7acd1164b005c 886 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 863 7.6E-233 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 Gene3D G3DSA:2.40.10.10 46 77 2.1E-13 T 28-03-2018 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 SMART SM00020 45 260 3.3E-66 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 78 83 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 Pfam PF00089 Trypsin 46 257 6.4E-51 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 123 137 3.7E-11 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 209 221 3.7E-11 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 68 83 3.7E-11 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 SUPERFAMILY SSF50494 16 261 2.26E-60 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 Gene3D G3DSA:2.40.10.10 78 266 5.8E-53 T 28-03-2018 SMD44_RS02680 8e0f83dca72d011856713435974c27cf 268 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 210 221 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS37595 70d47142cdb2066aaf8055f810dbb5d6 215 Gene3D G3DSA:1.10.260.40 39 69 4.6E-11 T 28-03-2018 SMD44_RS37595 70d47142cdb2066aaf8055f810dbb5d6 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 2.3E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS37595 70d47142cdb2066aaf8055f810dbb5d6 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 8.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS37595 70d47142cdb2066aaf8055f810dbb5d6 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 8.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS37595 70d47142cdb2066aaf8055f810dbb5d6 215 SUPERFAMILY SSF46689 3 77 2.15E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS37595 70d47142cdb2066aaf8055f810dbb5d6 215 Gene3D G3DSA:1.10.10.60 5 38 1.8E-18 T 28-03-2018 SMD44_RS42690 4fcd2f59f02f38126b0a1693670f1ffa 309 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 38 275 1.4E-42 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 SMD44_RS42690 4fcd2f59f02f38126b0a1693670f1ffa 309 SUPERFAMILY SSF56112 27 273 2.92E-22 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS42690 4fcd2f59f02f38126b0a1693670f1ffa 309 Gene3D G3DSA:3.90.1200.10 107 306 7.9E-10 T 28-03-2018 SMD44_RS34300 1f9660655d119a7901bc1fe762a21b53 185 Gene3D G3DSA:3.40.630.30 1 183 1.1E-22 T 28-03-2018 SMD44_RS34300 1f9660655d119a7901bc1fe762a21b53 185 SUPERFAMILY SSF55729 7 175 8.07E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS34300 1f9660655d119a7901bc1fe762a21b53 185 Pfam PF13302 Acetyltransferase (GNAT) domain 14 151 6.9E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS01135 6f6b748f79b5b6000c8b768d8a798380 422 SUPERFAMILY SSF53474 378 398 1.25E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01135 6f6b748f79b5b6000c8b768d8a798380 422 SUPERFAMILY SSF53474 132 347 1.25E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01135 6f6b748f79b5b6000c8b768d8a798380 422 Gene3D G3DSA:3.40.50.1820 74 418 5.1E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 SMART SM00344 1 110 1.6E-42 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 Gene3D G3DSA:3.30.70.920 53 147 3.3E-22 T 28-03-2018 SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 1.3E-19 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 2.7E-17 T 28-03-2018 SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 SUPERFAMILY SSF54909 66 150 7.91E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 Gene3D G3DSA:1.10.10.10 1 52 9.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03885 1ecc8290eafd983ace623e4e78ec567e 150 SUPERFAMILY SSF46785 1 60 2.19E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13240 fd4c54abac4df0e523563d977cded168 444 Pfam PF01595 Domain of unknown function DUF21 8 200 2.5E-33 T 28-03-2018 IPR002550 Domain of unknown function DUF21 SMD44_RS13240 fd4c54abac4df0e523563d977cded168 444 SUPERFAMILY SSF56176 361 437 3.54E-16 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS13240 fd4c54abac4df0e523563d977cded168 444 SUPERFAMILY SSF54631 211 345 1.39E-24 T 28-03-2018 SMD44_RS13240 fd4c54abac4df0e523563d977cded168 444 Gene3D G3DSA:3.10.580.10 195 341 2.6E-28 T 28-03-2018 SMD44_RS13240 fd4c54abac4df0e523563d977cded168 444 Pfam PF00571 CBS domain 219 272 0.0022 T 28-03-2018 IPR000644 CBS domain SMD44_RS13240 fd4c54abac4df0e523563d977cded168 444 Gene3D G3DSA:3.30.465.10 342 432 1.3E-22 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS13240 fd4c54abac4df0e523563d977cded168 444 SMART SM01091 356 433 1.8E-18 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS13240 fd4c54abac4df0e523563d977cded168 444 Pfam PF03471 Transporter associated domain 361 431 1.5E-16 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS32880 d996e9a98f49e9f68142b4ee44932827 250 Gene3D G3DSA:1.10.10.60 202 248 9.7E-7 T 28-03-2018 SMD44_RS32880 d996e9a98f49e9f68142b4ee44932827 250 Gene3D G3DSA:1.10.10.60 117 201 4.3E-4 T 28-03-2018 SMD44_RS32880 d996e9a98f49e9f68142b4ee44932827 250 Pfam PF12833 Helix-turn-helix domain 172 246 1.2E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS32880 d996e9a98f49e9f68142b4ee44932827 250 SMART SM00342 165 247 4.6E-9 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS28945 9f2ac3dbd961e529f886888abab953db 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28945 9f2ac3dbd961e529f886888abab953db 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28945 9f2ac3dbd961e529f886888abab953db 212 Gene3D G3DSA:1.10.357.10 64 200 1.3E-15 T 28-03-2018 SMD44_RS28945 9f2ac3dbd961e529f886888abab953db 212 SUPERFAMILY SSF46689 5 84 1.95E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS28945 9f2ac3dbd961e529f886888abab953db 212 Gene3D G3DSA:1.10.10.60 2 63 1.2E-17 T 28-03-2018 SMD44_RS28945 9f2ac3dbd961e529f886888abab953db 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 2.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02505 37b23480c689fad0628c930b6a2a8bde 315 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 28-03-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 SMD44_RS02505 37b23480c689fad0628c930b6a2a8bde 315 Gene3D G3DSA:3.90.245.10 1 310 1.5E-114 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SMD44_RS02505 37b23480c689fad0628c930b6a2a8bde 315 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 300 1.0E-94 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SMD44_RS02505 37b23480c689fad0628c930b6a2a8bde 315 SUPERFAMILY SSF53590 3 311 6.02E-106 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SMD44_RS29535 33626eb530abb534ad9fae7f85cb4564 411 SMART SM00387 311 408 9.6E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29535 33626eb530abb534ad9fae7f85cb4564 411 Gene3D G3DSA:3.30.565.10 150 407 3.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29535 33626eb530abb534ad9fae7f85cb4564 411 Pfam PF07730 Histidine kinase 208 273 1.6E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS29535 33626eb530abb534ad9fae7f85cb4564 411 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 406 3.3E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29535 33626eb530abb534ad9fae7f85cb4564 411 PIRSF PIRSF037434 11 411 2.6E-67 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS SMD44_RS29535 33626eb530abb534ad9fae7f85cb4564 411 SUPERFAMILY SSF55874 285 406 3.01E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS33995 9b2859bb2cd9c604a004ba7b029dfec4 427 PIRSF PIRSF000521 19 127 0.001 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS33995 9b2859bb2cd9c604a004ba7b029dfec4 427 PIRSF PIRSF000521 118 427 6.5E-35 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS33995 9b2859bb2cd9c604a004ba7b029dfec4 427 SUPERFAMILY SSF53383 15 425 1.06E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS33995 9b2859bb2cd9c604a004ba7b029dfec4 427 Gene3D G3DSA:3.90.1150.10 6 160 1.6E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS33995 9b2859bb2cd9c604a004ba7b029dfec4 427 Gene3D G3DSA:3.40.640.10 163 309 2.6E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS33995 9b2859bb2cd9c604a004ba7b029dfec4 427 Pfam PF00202 Aminotransferase class-III 24 424 3.4E-84 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS33995 9b2859bb2cd9c604a004ba7b029dfec4 427 Gene3D G3DSA:3.90.1150.10 310 427 1.1E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS31660 5d756d7c707e8ef4dafd73b044fde40f 395 Gene3D G3DSA:3.40.720.10 49 391 5.7E-35 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD44_RS31660 5d756d7c707e8ef4dafd73b044fde40f 395 SUPERFAMILY SSF53649 52 391 1.13E-61 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD44_RS31660 5d756d7c707e8ef4dafd73b044fde40f 395 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 57 380 4.0E-42 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SMD44_RS01910 7beab0e8f990d5acda6688812039ce1b 292 SUPERFAMILY SSF53901 15 291 4.95E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01910 7beab0e8f990d5acda6688812039ce1b 292 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 86 165 6.9E-14 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01910 7beab0e8f990d5acda6688812039ce1b 292 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 203 292 1.9E-18 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS01910 7beab0e8f990d5acda6688812039ce1b 292 Gene3D G3DSA:3.40.47.10 141 292 2.7E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01910 7beab0e8f990d5acda6688812039ce1b 292 Gene3D G3DSA:3.40.47.10 2 140 1.2E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 SUPERFAMILY SSF56784 19 219 3.25E-44 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 21 199 9.1E-23 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 92 199 2.7E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 Gene3D G3DSA:3.40.50.1000 82 213 1.1E-23 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 18 29 4.3E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 4.3E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 4.3E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 4.3E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS08220 3988bfe32bf72dbc63a920974436ce32 231 Gene3D G3DSA:1.10.150.240 31 81 5.2E-16 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS21095 93dcf618c2a4556f927f8be91d7ca36e 171 SUPERFAMILY SSF82708 126 170 1.12E-11 T 28-03-2018 IPR001374 R3H domain GO:0003676 SMD44_RS21095 93dcf618c2a4556f927f8be91d7ca36e 171 Pfam PF01424 R3H domain 113 168 2.8E-15 T 28-03-2018 IPR001374 R3H domain GO:0003676 SMD44_RS21095 93dcf618c2a4556f927f8be91d7ca36e 171 SMART SM00393 93 171 3.9E-28 T 28-03-2018 IPR001374 R3H domain GO:0003676 SMD44_RS21095 93dcf618c2a4556f927f8be91d7ca36e 171 Gene3D G3DSA:3.30.300.20 21 102 2.3E-20 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS21095 93dcf618c2a4556f927f8be91d7ca36e 171 Gene3D G3DSA:3.30.1370.50 104 171 5.0E-20 T 28-03-2018 IPR001374 R3H domain GO:0003676 SMD44_RS35230 bb3c412e010155a29c6cfa5c96d95ef2 818 SUPERFAMILY SSF52317 48 275 4.58E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS35230 bb3c412e010155a29c6cfa5c96d95ef2 818 Gene3D G3DSA:3.40.50.880 44 284 5.7E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS35230 bb3c412e010155a29c6cfa5c96d95ef2 818 SUPERFAMILY SSF50952 303 627 7.19E-18 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMD44_RS35230 bb3c412e010155a29c6cfa5c96d95ef2 818 SUPERFAMILY SSF50952 692 786 7.19E-18 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMD44_RS35230 bb3c412e010155a29c6cfa5c96d95ef2 818 Pfam PF06283 Trehalose utilisation 49 271 1.2E-70 T 28-03-2018 IPR029010 ThuA-like domain SMD44_RS35230 bb3c412e010155a29c6cfa5c96d95ef2 818 Gene3D G3DSA:2.120.10.30 285 803 1.2E-64 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS35230 bb3c412e010155a29c6cfa5c96d95ef2 818 Pfam PF07995 Glucose / Sorbosone dehydrogenase 345 613 1.2E-24 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMD44_RS04870 8e4d29bb68f9241a755df9965a6f1c23 229 SMART SM00873 64 218 3.6E-22 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD44_RS04870 8e4d29bb68f9241a755df9965a6f1c23 229 Pfam PF03483 B3/4 domain 66 195 6.2E-22 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD44_RS04870 8e4d29bb68f9241a755df9965a6f1c23 229 SUPERFAMILY SSF56037 52 198 1.96E-30 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMD44_RS04870 8e4d29bb68f9241a755df9965a6f1c23 229 Gene3D G3DSA:3.50.40.10 61 205 8.0E-27 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMD44_RS34585 0be76e80a3757e714f2f1b749000b153 365 SUPERFAMILY SSF50952 36 343 6.67E-38 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMD44_RS34585 0be76e80a3757e714f2f1b749000b153 365 Pfam PF07995 Glucose / Sorbosone dehydrogenase 53 349 1.1E-73 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMD44_RS34585 0be76e80a3757e714f2f1b749000b153 365 Gene3D G3DSA:2.120.10.30 26 274 4.4E-60 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS34585 0be76e80a3757e714f2f1b749000b153 365 Gene3D G3DSA:2.120.10.30 275 362 2.9E-5 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS28940 932c6eea645f219a9de16916bfa9a6fa 260 Gene3D G3DSA:3.40.50.300 1 243 3.4E-69 T 28-03-2018 SMD44_RS28940 932c6eea645f219a9de16916bfa9a6fa 260 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS28940 932c6eea645f219a9de16916bfa9a6fa 260 Pfam PF00005 ABC transporter 24 166 3.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS28940 932c6eea645f219a9de16916bfa9a6fa 260 SMART SM00382 32 216 2.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS28940 932c6eea645f219a9de16916bfa9a6fa 260 SUPERFAMILY SSF52540 3 226 1.33E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS33925 56c4d677709b1c0a207f1eedd0bdf010 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 207 6.4E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS33925 56c4d677709b1c0a207f1eedd0bdf010 214 SUPERFAMILY SSF161098 11 196 1.57E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS33925 56c4d677709b1c0a207f1eedd0bdf010 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 105 9.8E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD44_RS33925 56c4d677709b1c0a207f1eedd0bdf010 214 Gene3D G3DSA:1.10.3720.10 1 213 3.2E-35 T 28-03-2018 SMD44_RS41750 94b5b556ee826fa97100efa7915d563d 546 Gene3D G3DSA:2.60.40.650 443 546 5.5E-25 T 28-03-2018 SMD44_RS41750 94b5b556ee826fa97100efa7915d563d 546 Gene3D G3DSA:3.90.420.10 233 442 2.5E-46 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS41750 94b5b556ee826fa97100efa7915d563d 546 Pfam PF00174 Oxidoreductase molybdopterin binding domain 267 419 4.3E-32 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS41750 94b5b556ee826fa97100efa7915d563d 546 SUPERFAMILY SSF81296 436 545 9.1E-24 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS41750 94b5b556ee826fa97100efa7915d563d 546 SUPERFAMILY SSF56524 249 443 2.75E-47 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS25225 840b87fd2c67b52dd39ecedb717fffe6 286 SUPERFAMILY SSF51735 3 255 1.04E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS25225 840b87fd2c67b52dd39ecedb717fffe6 286 Pfam PF13460 NAD(P)H-binding 7 185 2.7E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS25225 840b87fd2c67b52dd39ecedb717fffe6 286 Gene3D G3DSA:3.40.50.720 153 232 0.48 T 28-03-2018 SMD44_RS25225 840b87fd2c67b52dd39ecedb717fffe6 286 Gene3D G3DSA:3.40.50.720 1 152 1.6E-23 T 28-03-2018 SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 593 0.0 T 28-03-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 SUPERFAMILY SSF52518 370 564 7.15E-51 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 553 1.6E-33 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 1.6E-50 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 Gene3D G3DSA:3.40.50.970 360 583 3.8E-43 T 28-03-2018 SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 Gene3D G3DSA:3.40.50.1220 191 359 1.1E-41 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 SUPERFAMILY SSF52467 157 360 3.47E-45 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 Gene3D G3DSA:3.40.50.970 1 190 2.3E-49 T 28-03-2018 SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 328 1.5E-34 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD44_RS33300 f6a46b8dda5f155919cb783fb7266772 595 SUPERFAMILY SSF52518 1 185 1.24E-49 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS14830 e158d89171c643f9a0b01391856dd4cd 125 SUPERFAMILY SSF54427 5 117 1.95E-18 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS14830 e158d89171c643f9a0b01391856dd4cd 125 Gene3D G3DSA:3.10.450.50 2 118 9.5E-13 T 28-03-2018 SMD44_RS14830 e158d89171c643f9a0b01391856dd4cd 125 Pfam PF12680 SnoaL-like domain 11 109 2.8E-6 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 Gene3D G3DSA:2.40.100.10 1 163 2.7E-67 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 51 63 2.2E-36 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 94 109 2.2E-36 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 109 121 2.2E-36 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 137 2.2E-36 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 22 37 2.2E-36 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 158 8.2E-45 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 PIRSF PIRSF001467 1 163 1.5E-71 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 SUPERFAMILY SSF50891 3 160 5.84E-66 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS37755 c42420150965373fc5f0e119ae468680 163 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 46 63 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 Gene3D G3DSA:2.60.40.10 1 83 8.7E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 PIRSF PIRSF006337 1 579 4.4E-227 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 SMART SM00642 78 498 1.1E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 Pfam PF11941 Domain of unknown function (DUF3459) 490 578 2.8E-17 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 SUPERFAMILY SSF51445 74 504 2.23E-102 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 SUPERFAMILY SSF81296 1 77 8.2E-15 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 1 544 9.3E-230 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 Gene3D G3DSA:2.60.40.1180 519 580 9.1E-4 T 28-03-2018 SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 Pfam PF00128 Alpha amylase, catalytic domain 108 189 1.9E-9 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 Gene3D G3DSA:1.10.10.760 434 468 2.4E-18 T 28-03-2018 SMD44_RS32660 c3c8fb8e065cf169afb52d41c47376b0 581 Gene3D G3DSA:3.20.20.80 87 433 1.5E-61 T 28-03-2018 SMD44_RS26390 ea0f38353398543316eb1cf8a442bb51 340 SUPERFAMILY SSF50129 1 137 5.39E-33 T 28-03-2018 IPR011032 GroES-like SMD44_RS26390 ea0f38353398543316eb1cf8a442bb51 340 SMART SM00829 17 332 4.2E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS26390 ea0f38353398543316eb1cf8a442bb51 340 Gene3D G3DSA:3.90.180.10 1 148 1.7E-32 T 28-03-2018 SMD44_RS26390 ea0f38353398543316eb1cf8a442bb51 340 Pfam PF16884 N-terminal domain of oxidoreductase 5 111 1.5E-36 T 28-03-2018 SMD44_RS26390 ea0f38353398543316eb1cf8a442bb51 340 Gene3D G3DSA:3.40.50.720 149 276 9.1E-24 T 28-03-2018 SMD44_RS26390 ea0f38353398543316eb1cf8a442bb51 340 Pfam PF00107 Zinc-binding dehydrogenase 158 289 2.0E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS26390 ea0f38353398543316eb1cf8a442bb51 340 SUPERFAMILY SSF51735 123 299 1.78E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS15165 0633a48b34902073959da143527b1b88 358 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 13 351 1.7E-130 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 SMD44_RS15165 0633a48b34902073959da143527b1b88 358 Gene3D G3DSA:3.20.20.30 16 352 7.3E-78 T 28-03-2018 SMD44_RS15165 0633a48b34902073959da143527b1b88 358 SUPERFAMILY SSF51679 13 350 4.71E-79 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS15165 0633a48b34902073959da143527b1b88 358 Pfam PF00296 Luciferase-like monooxygenase 14 327 2.1E-40 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 PIRSF PIRSF000106 33 404 1.1E-71 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 Gene3D G3DSA:3.40.50.10380 26 174 4.8E-38 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 SMART SM00919 177 397 6.3E-108 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 SUPERFAMILY SSF53223 27 175 1.8E-56 T 28-03-2018 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 Pfam PF03949 Malic enzyme, NAD binding domain 179 378 1.6E-19 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 Pfam PF00390 Malic enzyme, N-terminal domain 34 165 3.0E-28 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 SMART SM01274 32 165 2.8E-80 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 Gene3D G3DSA:3.40.50.720 175 404 1.5E-68 T 28-03-2018 SMD44_RS28535 ba4ef74a8089d56ea9552fbdba7a4194 404 SUPERFAMILY SSF51735 177 403 4.96E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 Gene3D G3DSA:3.40.50.720 1 206 1.0E-52 T 28-03-2018 SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 SUPERFAMILY SSF51735 9 237 3.45E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12115 40417395c68bea2ac53276ab692a3328 258 Pfam PF00106 short chain dehydrogenase 10 206 7.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS15760 5208d31d01bcb1bb0e83e7b52b11311d 215 SUPERFAMILY SSF161098 13 198 4.58E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15760 5208d31d01bcb1bb0e83e7b52b11311d 215 Gene3D G3DSA:1.10.3720.10 1 211 4.3E-24 T 28-03-2018 SMD44_RS15760 5208d31d01bcb1bb0e83e7b52b11311d 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 206 7.3E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS33470 cbc0a183095abfca89ddeac2f81ce329 197 SUPERFAMILY SSF53254 2 194 2.36E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS33470 cbc0a183095abfca89ddeac2f81ce329 197 Gene3D G3DSA:3.40.50.1240 1 196 9.6E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS33470 cbc0a183095abfca89ddeac2f81ce329 197 PIRSF PIRSF000709 2 103 1.3E-4 T 28-03-2018 SMD44_RS33470 cbc0a183095abfca89ddeac2f81ce329 197 SMART SM00855 3 156 4.8E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS33470 cbc0a183095abfca89ddeac2f81ce329 197 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 195 7.6E-50 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS25510 9ef143839aafbf9380c65129e8c3ac26 138 SUPERFAMILY SSF54189 44 135 3.96E-32 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25510 9ef143839aafbf9380c65129e8c3ac26 138 ProSitePatterns PS00050 Ribosomal protein L23 signature. 119 134 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25510 9ef143839aafbf9380c65129e8c3ac26 138 Pfam PF00276 Ribosomal protein L23 48 133 1.2E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25510 9ef143839aafbf9380c65129e8c3ac26 138 Gene3D G3DSA:3.30.70.330 44 138 2.9E-33 T 28-03-2018 SMD44_RS25510 9ef143839aafbf9380c65129e8c3ac26 138 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 47 136 22.154 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SMD44_RS04265 6c49f43783c952377c239ed038aa3371 236 SUPERFAMILY SSF49899 17 180 8.31E-12 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS04265 6c49f43783c952377c239ed038aa3371 236 Gene3D G3DSA:2.60.120.200 2 169 5.5E-12 T 28-03-2018 SMD44_RS04265 6c49f43783c952377c239ed038aa3371 236 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 20 157 1.2E-9 T 28-03-2018 SMD44_RS04265 6c49f43783c952377c239ed038aa3371 236 Gene3D G3DSA:2.60.120.200 170 228 0.2 T 28-03-2018 SMD44_RS31465 fd47287b665968f8704246a7ba7a49c5 219 Gene3D G3DSA:3.40.50.1240 3 214 6.2E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS31465 fd47287b665968f8704246a7ba7a49c5 219 SUPERFAMILY SSF53254 4 199 9.3E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS31465 fd47287b665968f8704246a7ba7a49c5 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 193 2.6E-36 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS31465 fd47287b665968f8704246a7ba7a49c5 219 SMART SM00855 6 166 1.5E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS31465 fd47287b665968f8704246a7ba7a49c5 219 PIRSF PIRSF000709 1 185 1.6E-9 T 28-03-2018 SMD44_RS31465 fd47287b665968f8704246a7ba7a49c5 219 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMD44_RS43785 2b892666d8756184c3cdf8039473cba7 171 Gene3D G3DSA:3.40.630.30 9 164 1.5E-26 T 28-03-2018 SMD44_RS43785 2b892666d8756184c3cdf8039473cba7 171 PIRSF PIRSF037663 9 165 2.6E-55 T 28-03-2018 IPR017255 Acetyltransferase, GNAT, predicted SMD44_RS43785 2b892666d8756184c3cdf8039473cba7 171 Pfam PF00583 Acetyltransferase (GNAT) family 51 140 2.2E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS43785 2b892666d8756184c3cdf8039473cba7 171 SUPERFAMILY SSF55729 18 164 2.23E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS41610 500e4f6ea699514de056b3d6c61cec38 493 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 33 443 2.6E-38 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMD44_RS41610 500e4f6ea699514de056b3d6c61cec38 493 PIRSF PIRSF002744 6 481 4.7E-93 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMD44_RS05820 d2c88e805f8225ce19ec313a7f59d878 378 Gene3D G3DSA:3.40.640.10 48 273 3.9E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS05820 d2c88e805f8225ce19ec313a7f59d878 378 Pfam PF00155 Aminotransferase class I and II 33 373 2.2E-58 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS05820 d2c88e805f8225ce19ec313a7f59d878 378 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 228 237 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD44_RS05820 d2c88e805f8225ce19ec313a7f59d878 378 Gene3D G3DSA:3.90.1150.10 274 377 8.1E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS05820 d2c88e805f8225ce19ec313a7f59d878 378 SUPERFAMILY SSF53383 8 375 1.46E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS31670 b7f109c4b6618dae256553578e67f145 271 SUPERFAMILY SSF54593 22 134 8.23E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS31670 b7f109c4b6618dae256553578e67f145 271 Gene3D G3DSA:3.10.180.10 148 270 2.3E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS31670 b7f109c4b6618dae256553578e67f145 271 Gene3D G3DSA:3.10.180.10 2 143 9.9E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS31670 b7f109c4b6618dae256553578e67f145 271 SUPERFAMILY SSF54593 151 262 3.22E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS28170 c7276761b44096767d3ddeac8b320100 152 Pfam PF02391 MoaE protein 22 133 4.7E-37 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS28170 c7276761b44096767d3ddeac8b320100 152 Gene3D G3DSA:3.90.1170.40 16 152 2.9E-48 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS28170 c7276761b44096767d3ddeac8b320100 152 SUPERFAMILY SSF54690 20 151 7.32E-41 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS19340 4ea01e05691fd152e687dadcfd5c8aef 308 Pfam PF00583 Acetyltransferase (GNAT) family 199 295 1.8E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS19340 4ea01e05691fd152e687dadcfd5c8aef 308 Pfam PF00583 Acetyltransferase (GNAT) family 62 130 4.4E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS19340 4ea01e05691fd152e687dadcfd5c8aef 308 Gene3D G3DSA:3.40.630.30 154 307 2.7E-26 T 28-03-2018 SMD44_RS19340 4ea01e05691fd152e687dadcfd5c8aef 308 PIRSF PIRSF021524 8 308 1.6E-109 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 SMD44_RS19340 4ea01e05691fd152e687dadcfd5c8aef 308 SUPERFAMILY SSF55729 14 304 2.35E-50 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS19340 4ea01e05691fd152e687dadcfd5c8aef 308 Gene3D G3DSA:3.40.630.30 15 153 1.8E-13 T 28-03-2018 SMD44_RS19340 4ea01e05691fd152e687dadcfd5c8aef 308 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 13 306 36.394 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 SMD44_RS19340 4ea01e05691fd152e687dadcfd5c8aef 308 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 16 304 1.1E-119 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 SMD44_RS43635 26db458f99411902caf5ea2bcb763a60 240 Pfam PF01695 IstB-like ATP binding protein 91 198 2.4E-14 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 SMD44_RS43635 26db458f99411902caf5ea2bcb763a60 240 SUPERFAMILY SSF52540 64 217 1.8E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43635 26db458f99411902caf5ea2bcb763a60 240 Gene3D G3DSA:3.40.50.300 56 227 1.2E-8 T 28-03-2018 SMD44_RS13625 a2d64db2ffe2d0e79a898e09ff3a7d6c 288 Gene3D G3DSA:3.40.50.720 1 138 5.2E-19 T 28-03-2018 SMD44_RS13625 a2d64db2ffe2d0e79a898e09ff3a7d6c 288 Gene3D G3DSA:3.90.25.10 139 242 9.4E-5 T 28-03-2018 SMD44_RS13625 a2d64db2ffe2d0e79a898e09ff3a7d6c 288 Pfam PF13460 NAD(P)H-binding 7 179 4.0E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS13625 a2d64db2ffe2d0e79a898e09ff3a7d6c 288 SUPERFAMILY SSF51735 2 273 3.2E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS13625 a2d64db2ffe2d0e79a898e09ff3a7d6c 288 TIGRFAM TIGR03649 ergot_EASG: ergot alkaloid biosynthesis protein, AFUA_2G17970 family 2 278 4.9E-78 T 28-03-2018 IPR019901 Ergot alkaloid biosynthesis protein SMD44_RS23280 9ed509a5cd99bf5e725a9ea1d8823817 54 Pfam PF14029 Protein of unknown function (DUF4244) 4 51 1.8E-21 T 28-03-2018 IPR025338 Protein of unknown function DUF4244 SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 618 3.5E-240 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 Pfam PF13522 Glutamine amidotransferase domain 67 194 1.8E-21 T 28-03-2018 SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 SUPERFAMILY SSF56235 2 223 1.03E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 Gene3D G3DSA:3.40.50.10490 245 459 3.4E-62 T 28-03-2018 SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 Gene3D G3DSA:3.60.20.10 2 244 9.6E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 Pfam PF01380 SIS domain 467 600 8.7E-24 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 Pfam PF01380 SIS domain 295 421 1.6E-33 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 SUPERFAMILY SSF53697 250 618 7.14E-105 T 28-03-2018 SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 Gene3D G3DSA:3.40.50.10490 460 616 2.8E-46 T 28-03-2018 SMD44_RS25690 f28714062ae05752f35c1e718f575a68 618 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 618 40.629 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMD44_RS07240 6f42c3935dc6d118129e9f29d0f8e5d2 107 SUPERFAMILY SSF46946 56 102 1.69E-7 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD44_RS07240 6f42c3935dc6d118129e9f29d0f8e5d2 107 Gene3D G3DSA:1.10.8.50 68 101 2.3E-5 T 28-03-2018 SMD44_RS07240 6f42c3935dc6d118129e9f29d0f8e5d2 107 PIRSF PIRSF002134 41 105 1.4E-7 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS07240 6f42c3935dc6d118129e9f29d0f8e5d2 107 Gene3D G3DSA:1.10.150.20 10 67 0.039 T 28-03-2018 SMD44_RS08435 2823bf401d8a3df529c0010df8111ddc 134 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 8 131 27.457 T 28-03-2018 IPR023006 Uncharacterised protein family UPF0225 SMD44_RS08435 2823bf401d8a3df529c0010df8111ddc 134 SUPERFAMILY SSF54427 32 132 2.59E-33 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS08435 2823bf401d8a3df529c0010df8111ddc 134 Gene3D G3DSA:3.10.450.50 10 134 1.1E-44 T 28-03-2018 SMD44_RS32815 87d8e2a2033957608fbbca174223b3d1 376 Pfam PF13379 NMT1-like family 59 295 7.6E-26 T 28-03-2018 SMD44_RS32815 87d8e2a2033957608fbbca174223b3d1 376 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 61 354 2.3E-57 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 SMD44_RS32815 87d8e2a2033957608fbbca174223b3d1 376 Gene3D G3DSA:3.40.190.10 162 355 6.8E-31 T 28-03-2018 SMD44_RS32815 87d8e2a2033957608fbbca174223b3d1 376 SUPERFAMILY SSF53850 60 291 5.14E-36 T 28-03-2018 SMD44_RS32815 87d8e2a2033957608fbbca174223b3d1 376 Gene3D G3DSA:3.40.190.10 57 161 3.0E-12 T 28-03-2018 SMD44_RS38265 f1969f82d7a5fc4603b8da500cb9f7c0 73 Pfam PF11706 CGNR zinc finger 49 71 2.1E-5 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS38265 f1969f82d7a5fc4603b8da500cb9f7c0 73 SUPERFAMILY SSF160904 49 70 1.57E-5 T 28-03-2018 SMD44_RS38265 f1969f82d7a5fc4603b8da500cb9f7c0 73 Gene3D G3DSA:1.10.3300.10 46 73 3.4E-4 T 28-03-2018 IPR023286 ABATE domain SMD44_RS35520 6cdc972fabd5134b74e5a93156aebf29 374 SUPERFAMILY SSF48576 50 373 2.24E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS35520 6cdc972fabd5134b74e5a93156aebf29 374 Pfam PF00348 Polyprenyl synthetase 71 307 1.9E-53 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMD44_RS35520 6cdc972fabd5134b74e5a93156aebf29 374 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 121 135 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMD44_RS35520 6cdc972fabd5134b74e5a93156aebf29 374 Gene3D G3DSA:1.10.600.10 13 374 1.9E-94 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 Pfam PF08281 Sigma-70, region 4 104 155 2.3E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 SUPERFAMILY SSF88659 96 160 3.55E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 159 8.7E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 SUPERFAMILY SSF88946 2 75 3.26E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 Pfam PF04542 Sigma-70 region 2 16 78 1.2E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 34 65 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 162 1.0E-60 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 Gene3D G3DSA:1.10.10.10 76 166 8.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23940 82eac92022e983db225cec4edc1a4400 185 Gene3D G3DSA:1.10.1740.10 1 75 1.0E-11 T 28-03-2018 SMD44_RS10260 35140ccc110602cbeaea9ed6398457fd 193 SUPERFAMILY SSF53155 22 101 1.63E-11 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS10260 35140ccc110602cbeaea9ed6398457fd 193 Gene3D G3DSA:3.30.160.70 6 102 1.2E-21 T 28-03-2018 SMD44_RS10260 35140ccc110602cbeaea9ed6398457fd 193 Gene3D G3DSA:1.10.10.10 103 191 3.1E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10260 35140ccc110602cbeaea9ed6398457fd 193 SUPERFAMILY SSF46767 107 187 3.4E-26 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS10260 35140ccc110602cbeaea9ed6398457fd 193 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 107 185 3.5E-27 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS10260 35140ccc110602cbeaea9ed6398457fd 193 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 156 162 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS10260 35140ccc110602cbeaea9ed6398457fd 193 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 24 186 38.923 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SMD44_RS10260 35140ccc110602cbeaea9ed6398457fd 193 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 107 187 3.8E-28 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS33225 70771218284fd3ba0eb81cfe2a345bb9 261 SUPERFAMILY SSF53474 1 259 7.63E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS33225 70771218284fd3ba0eb81cfe2a345bb9 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS33225 70771218284fd3ba0eb81cfe2a345bb9 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS33225 70771218284fd3ba0eb81cfe2a345bb9 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS33225 70771218284fd3ba0eb81cfe2a345bb9 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS33225 70771218284fd3ba0eb81cfe2a345bb9 261 Pfam PF12697 Alpha/beta hydrolase family 22 252 8.3E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS33225 70771218284fd3ba0eb81cfe2a345bb9 261 Gene3D G3DSA:3.40.50.1820 2 260 4.6E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS26155 5a4fedc889d60ab750d5de89bf8088c5 268 Gene3D G3DSA:3.40.190.10 2 256 9.9E-5 T 28-03-2018 SMD44_RS26155 5a4fedc889d60ab750d5de89bf8088c5 268 SUPERFAMILY SSF89392 48 145 8.63E-7 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD44_RS26155 5a4fedc889d60ab750d5de89bf8088c5 268 SUPERFAMILY SSF89392 178 246 8.63E-7 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD44_RS08865 781d98b40b12dc3950164c898e55df9e 148 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 43 69 4.6E-27 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS08865 781d98b40b12dc3950164c898e55df9e 148 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 106 122 4.6E-27 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS08865 781d98b40b12dc3950164c898e55df9e 148 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 123 139 4.6E-27 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS08865 781d98b40b12dc3950164c898e55df9e 148 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 46 136 8.0E-33 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS08865 781d98b40b12dc3950164c898e55df9e 148 Gene3D G3DSA:3.30.350.10 42 148 3.1E-30 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS08865 781d98b40b12dc3950164c898e55df9e 148 SUPERFAMILY SSF55399 41 148 1.31E-35 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS08865 781d98b40b12dc3950164c898e55df9e 148 Pfam PF00720 Subtilisin inhibitor-like 42 134 1.4E-32 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS08865 781d98b40b12dc3950164c898e55df9e 148 Hamap MF_00778 Probable subtilase-type protease inhibitor [sti]. 41 148 29.723 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 SMART SM00938 4 105 2.8E-56 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 Gene3D G3DSA:3.30.70.120 1 109 1.0E-45 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 PRINTS PR00340 P-II protein signature 2 17 9.6E-37 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 PRINTS PR00340 P-II protein signature 52 75 9.6E-37 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 PRINTS PR00340 P-II protein signature 83 103 9.6E-37 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 PRINTS PR00340 P-II protein signature 23 41 9.6E-37 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.3E-39 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 SUPERFAMILY SSF54913 1 112 2.0E-41 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMD44_RS30435 9b3c812e2593feb756bef01b040cbbcc 112 PIRSF PIRSF039144 1 112 1.7E-49 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SUPERFAMILY SSF81901 363 524 4.01E-26 T 28-03-2018 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 157 169 55.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 422 452 13.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 564 593 0.036 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 278 292 0.26 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 410 420 120.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 454 484 0.0015 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 338 356 120.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 609 625 11.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF08238 Sel1 repeat 518 561 1.2E-6 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Gene3D G3DSA:1.25.40.10 462 499 1.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 107 138 0.04 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 562 593 12.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 517 561 100.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 626 657 38.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 357 388 16.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 139 169 24.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 325 356 8.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 389 420 62.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 75 106 130.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 594 625 8.2 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 453 484 1.1E-4 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 43 74 130.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 421 452 2.4 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00671 293 324 41.0 T 28-03-2018 IPR006597 Sel1-like repeat SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00028 357 390 42.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00028 43 76 300.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00028 453 486 14.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SMART SM00028 626 659 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Gene3D G3DSA:2.60.40.1180 442 461 9.0E-5 T 28-03-2018 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Pfam PF13432 Tetratricopeptide repeat 49 107 0.0029 T 28-03-2018 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SUPERFAMILY SSF81901 547 665 2.49E-21 T 28-03-2018 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Gene3D G3DSA:1.25.40.10 351 441 6.7E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Gene3D G3DSA:1.25.40.10 168 350 1.3E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SUPERFAMILY SSF81901 37 177 3.4E-16 T 28-03-2018 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Gene3D G3DSA:1.25.40.10 587 667 9.7E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Gene3D G3DSA:1.25.40.10 101 167 3.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Gene3D G3DSA:1.25.40.10 9 100 1.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 Gene3D G3DSA:1.25.40.10 500 586 5.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS28200 69c16305f23ef193690936a9491803cf 677 SUPERFAMILY SSF81901 278 395 1.44E-18 T 28-03-2018 SMD44_RS13490 e11aabd1d25edbcefe0e66f8b490d2bb 675 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 9 231 6.9E-30 T 28-03-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal SMD44_RS13490 e11aabd1d25edbcefe0e66f8b490d2bb 675 SUPERFAMILY SSF48208 245 670 2.17E-58 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS13490 e11aabd1d25edbcefe0e66f8b490d2bb 675 Gene3D G3DSA:1.50.10.10 467 669 3.4E-29 T 28-03-2018 SMD44_RS13490 e11aabd1d25edbcefe0e66f8b490d2bb 675 Gene3D G3DSA:1.50.10.10 252 466 1.0E-21 T 28-03-2018 SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 3.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 Gene3D G3DSA:1.10.10.10 1 88 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 SUPERFAMILY SSF46785 3 107 2.18E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 SUPERFAMILY SSF53850 96 298 2.33E-18 T 28-03-2018 SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 Pfam PF03466 LysR substrate binding domain 97 283 5.1E-23 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 Gene3D G3DSA:3.40.190.10 94 184 7.9E-15 T 28-03-2018 SMD44_RS21995 f7f92f9cb80cfb5683139a43782e23fa 363 Gene3D G3DSA:3.40.190.10 185 268 1.4E-11 T 28-03-2018 SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 Gene3D G3DSA:3.40.50.970 378 551 2.8E-35 T 28-03-2018 SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 SUPERFAMILY SSF52467 181 376 2.89E-37 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 348 1.1E-30 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 440 459 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 Gene3D G3DSA:3.40.50.1220 218 377 2.4E-36 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 27 196 6.2E-44 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 407 547 1.4E-34 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 SUPERFAMILY SSF52518 26 201 1.57E-38 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 SUPERFAMILY SSF52518 384 549 8.58E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS14895 0890d489fac58ae723c545af53fd64e8 561 Gene3D G3DSA:3.40.50.970 21 217 3.2E-39 T 28-03-2018 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 Pfam PF00199 Catalase 5 383 1.4E-185 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 PIRSF PIRSF038928 1 480 2.6E-229 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 ProSitePatterns PS00438 Catalase proximal active site signature. 41 57 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 PRINTS PR00067 Catalase signature 120 138 4.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 PRINTS PR00067 Catalase signature 80 98 4.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 PRINTS PR00067 Catalase signature 18 41 4.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 PRINTS PR00067 Catalase signature 285 312 4.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 PRINTS PR00067 Catalase signature 317 343 4.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 PRINTS PR00067 Catalase signature 101 118 4.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 Pfam PF06628 Catalase-related immune-responsive 415 476 1.8E-17 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 SMART SM01060 5 387 3.3E-276 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 SUPERFAMILY SSF56634 3 478 4.06E-201 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 330 338 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS27475 c43ac8fd27d5a6f9e0a425f8a4e2f5ac 480 Gene3D G3DSA:2.40.180.10 1 354 2.5E-162 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS25340 8affa951098c5e11a785132384c28c9b 218 Pfam PF13460 NAD(P)H-binding 7 192 1.2E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS25340 8affa951098c5e11a785132384c28c9b 218 SUPERFAMILY SSF51735 1 205 5.5E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS25340 8affa951098c5e11a785132384c28c9b 218 Gene3D G3DSA:3.40.50.720 1 217 1.9E-29 T 28-03-2018 SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 Pfam PF08281 Sigma-70, region 4 142 193 1.0E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 Gene3D G3DSA:3.10.450.50 186 317 3.2E-18 T 28-03-2018 SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 Pfam PF04542 Sigma-70 region 2 47 110 1.6E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 SUPERFAMILY SSF88659 114 196 9.35E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 194 1.5E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 Gene3D G3DSA:1.10.1740.10 29 108 1.1E-14 T 28-03-2018 SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 SUPERFAMILY SSF88946 35 124 9.42E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 44 317 1.2E-106 T 28-03-2018 IPR014303 RNA polymerase sigma-70, ECF type SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 Gene3D G3DSA:1.10.10.10 109 185 2.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26345 a98319fe04d7c59f4a36f4a5a49c9d49 325 SUPERFAMILY SSF54427 207 316 6.08E-13 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS13110 3b25850994143b59ef98c529fbc94a53 387 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 14 327 1.0E-85 T 28-03-2018 IPR010148 CRISPR-associated protein, CT1975 SMD44_RS13110 3b25850994143b59ef98c529fbc94a53 387 Pfam PF09344 CT1975-like protein 15 370 1.9E-118 T 28-03-2018 IPR010148 CRISPR-associated protein, CT1975 SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 Pfam PF12840 Helix-turn-helix domain 5 63 7.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 SUPERFAMILY SSF46785 1 94 1.62E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 Gene3D G3DSA:1.10.10.10 1 95 3.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 SUPERFAMILY SSF55961 122 272 2.05E-23 T 28-03-2018 SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 SMART SM00418 5 83 8.7E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 4.9E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 4.9E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 4.9E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 132 272 1.8E-11 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMD44_RS01565 f7ee6afc0bc9944f18f6ed719db4a5f4 276 Gene3D G3DSA:3.30.530.20 120 276 1.9E-27 T 28-03-2018 IPR023393 START-like domain SMD44_RS24400 641702f568a9be1214e3d38cfcefc537 103 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 58 8.4E-10 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal SMD44_RS31320 3f6d5a574257dc8a1e2cd1063392cb18 180 Gene3D G3DSA:1.10.1740.10 8 90 1.4E-28 T 28-03-2018 SMD44_RS31320 3f6d5a574257dc8a1e2cd1063392cb18 180 Pfam PF08281 Sigma-70, region 4 120 171 2.5E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31320 3f6d5a574257dc8a1e2cd1063392cb18 180 SUPERFAMILY SSF88659 100 178 1.4E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31320 3f6d5a574257dc8a1e2cd1063392cb18 180 SUPERFAMILY SSF88946 3 100 2.98E-31 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31320 3f6d5a574257dc8a1e2cd1063392cb18 180 Pfam PF04542 Sigma-70 region 2 23 89 3.0E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31320 3f6d5a574257dc8a1e2cd1063392cb18 180 Gene3D G3DSA:1.10.10.10 99 178 3.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31320 3f6d5a574257dc8a1e2cd1063392cb18 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 175 7.5E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS09755 db581fec18c74748f6f7a140591f00e3 257 Pfam PF09339 IclR helix-turn-helix domain 14 64 4.8E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS09755 db581fec18c74748f6f7a140591f00e3 257 SUPERFAMILY SSF55781 79 252 2.29E-46 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS09755 db581fec18c74748f6f7a140591f00e3 257 Pfam PF01614 Bacterial transcriptional regulator 134 246 1.5E-28 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS09755 db581fec18c74748f6f7a140591f00e3 257 Gene3D G3DSA:3.30.450.40 77 254 1.8E-46 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS09755 db581fec18c74748f6f7a140591f00e3 257 Gene3D G3DSA:1.10.10.10 2 73 4.8E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09755 db581fec18c74748f6f7a140591f00e3 257 SMART SM00346 12 102 3.3E-19 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS09755 db581fec18c74748f6f7a140591f00e3 257 SUPERFAMILY SSF46785 12 84 4.68E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05190 52333d8cceaa323aaffa6d7d173c7921 196 Gene3D G3DSA:1.10.10.10 92 194 3.9E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20140 81f644c0a3cf5d9948be5302dfc659bc 477 Gene3D G3DSA:1.20.1250.20 1 194 9.8E-32 T 28-03-2018 SMD44_RS20140 81f644c0a3cf5d9948be5302dfc659bc 477 Gene3D G3DSA:1.20.1250.20 253 463 1.1E-24 T 28-03-2018 SMD44_RS20140 81f644c0a3cf5d9948be5302dfc659bc 477 SUPERFAMILY SSF103473 242 452 5.75E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20140 81f644c0a3cf5d9948be5302dfc659bc 477 SUPERFAMILY SSF103473 3 191 5.75E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20140 81f644c0a3cf5d9948be5302dfc659bc 477 Pfam PF07690 Major Facilitator Superfamily 13 403 8.0E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS12535 d247f9e0336ba6e5c84785ecfdd99624 715 Pfam PF13454 FAD-NAD(P)-binding 42 220 2.0E-41 T 28-03-2018 SMD44_RS12535 d247f9e0336ba6e5c84785ecfdd99624 715 Gene3D G3DSA:3.50.50.60 32 679 2.3E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 Pfam PF00334 Nucleoside diphosphate kinase 3 135 4.9E-52 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 5.2E-43 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 5.2E-43 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 5.2E-43 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 5.2E-43 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 5.2E-43 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 SMART SM00562 2 137 2.6E-75 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 137 32.765 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 Gene3D G3DSA:3.30.70.141 1 136 4.6E-51 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS14070 58068a02d4ef1d9fce9ee96a43e4194a 137 SUPERFAMILY SSF54919 2 135 6.02E-52 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS21625 08a3c92dcbcfa8971ec859ee24ffaef9 297 Pfam PF13649 Methyltransferase domain 88 187 2.2E-13 T 28-03-2018 SMD44_RS21625 08a3c92dcbcfa8971ec859ee24ffaef9 297 SUPERFAMILY SSF53335 62 277 1.39E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS21625 08a3c92dcbcfa8971ec859ee24ffaef9 297 Gene3D G3DSA:3.40.50.150 43 287 3.3E-26 T 28-03-2018 SMD44_RS08380 ef8031b29acb4aed38060c469de60ad6 184 Gene3D G3DSA:1.10.10.10 7 168 1.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21570 fbac121f28c1c5659f8d8abcc437cf1d 420 SUPERFAMILY SSF56801 36 352 1.22E-25 T 28-03-2018 SMD44_RS21570 fbac121f28c1c5659f8d8abcc437cf1d 420 Gene3D G3DSA:3.40.50.980 52 219 9.8E-11 T 28-03-2018 SMD44_RS21570 fbac121f28c1c5659f8d8abcc437cf1d 420 Pfam PF00501 AMP-binding enzyme 69 268 1.2E-5 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS04830 2284b0727a1c3ebfc9ee2d1272899cb0 653 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 146 158 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS04830 2284b0727a1c3ebfc9ee2d1272899cb0 653 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 29 52 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS04830 2284b0727a1c3ebfc9ee2d1272899cb0 653 Pfam PF00069 Protein kinase domain 23 238 2.6E-41 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS04830 2284b0727a1c3ebfc9ee2d1272899cb0 653 Gene3D G3DSA:3.30.200.20 4 109 7.1E-21 T 28-03-2018 SMD44_RS04830 2284b0727a1c3ebfc9ee2d1272899cb0 653 SMART SM00220 23 285 7.7E-58 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS04830 2284b0727a1c3ebfc9ee2d1272899cb0 653 Gene3D G3DSA:1.10.510.10 110 425 3.1E-43 T 28-03-2018 SMD44_RS04830 2284b0727a1c3ebfc9ee2d1272899cb0 653 SUPERFAMILY SSF56112 15 280 1.34E-65 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS41485 1bc38cf7c4144acaabbaeb5d9677b202 623 Gene3D G3DSA:3.30.565.10 505 623 1.4E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41485 1bc38cf7c4144acaabbaeb5d9677b202 623 SMART SM00387 526 617 4.6E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41485 1bc38cf7c4144acaabbaeb5d9677b202 623 Gene3D G3DSA:3.30.450.40 346 437 5.5E-9 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS41485 1bc38cf7c4144acaabbaeb5d9677b202 623 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 531 615 3.7E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41485 1bc38cf7c4144acaabbaeb5d9677b202 623 SUPERFAMILY SSF55781 276 395 1.22E-7 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS41485 1bc38cf7c4144acaabbaeb5d9677b202 623 Pfam PF07730 Histidine kinase 424 459 3.4E-6 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS41485 1bc38cf7c4144acaabbaeb5d9677b202 623 SUPERFAMILY SSF55874 527 615 1.44E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41485 1bc38cf7c4144acaabbaeb5d9677b202 623 Gene3D G3DSA:3.30.450.40 275 345 0.038 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS41205 6eb92bd675ca30604b5e42c3eb0d78ab 569 Gene3D G3DSA:2.30.38.10 345 430 1.1E-18 T 28-03-2018 SMD44_RS41205 6eb92bd675ca30604b5e42c3eb0d78ab 569 Pfam PF00501 AMP-binding enzyme 18 437 2.3E-69 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS41205 6eb92bd675ca30604b5e42c3eb0d78ab 569 Gene3D G3DSA:3.40.50.980 194 344 1.7E-36 T 28-03-2018 SMD44_RS41205 6eb92bd675ca30604b5e42c3eb0d78ab 569 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS41205 6eb92bd675ca30604b5e42c3eb0d78ab 569 SUPERFAMILY SSF56801 19 533 7.85E-111 T 28-03-2018 SMD44_RS41205 6eb92bd675ca30604b5e42c3eb0d78ab 569 Gene3D G3DSA:3.30.300.30 431 535 2.4E-25 T 28-03-2018 SMD44_RS41205 6eb92bd675ca30604b5e42c3eb0d78ab 569 Gene3D G3DSA:3.40.50.980 11 193 1.0E-26 T 28-03-2018 SMD44_RS41205 6eb92bd675ca30604b5e42c3eb0d78ab 569 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 523 8.7E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS06810 14750cdb3c8be0b944da8d2317c80989 433 Pfam PF07690 Major Facilitator Superfamily 46 390 3.3E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS06810 14750cdb3c8be0b944da8d2317c80989 433 Gene3D G3DSA:1.20.1250.20 231 433 7.5E-30 T 28-03-2018 SMD44_RS06810 14750cdb3c8be0b944da8d2317c80989 433 ProSitePatterns PS00217 Sugar transport proteins signature 2. 137 162 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS06810 14750cdb3c8be0b944da8d2317c80989 433 SUPERFAMILY SSF103473 24 431 2.49E-81 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS06810 14750cdb3c8be0b944da8d2317c80989 433 Gene3D G3DSA:1.20.1250.20 31 230 5.4E-33 T 28-03-2018 SMD44_RS15800 cbe78513818d04fb218778341d1b041b 597 SUPERFAMILY SSF52540 271 390 1.06E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15800 cbe78513818d04fb218778341d1b041b 597 SUPERFAMILY SSF52540 140 212 1.06E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15800 cbe78513818d04fb218778341d1b041b 597 Pfam PF04851 Type III restriction enzyme, res subunit 27 178 7.9E-14 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD44_RS15800 cbe78513818d04fb218778341d1b041b 597 Gene3D G3DSA:3.40.50.300 23 185 4.1E-21 T 28-03-2018 SMD44_RS15800 cbe78513818d04fb218778341d1b041b 597 SMART SM00487 24 200 5.4E-19 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS15800 cbe78513818d04fb218778341d1b041b 597 Gene3D G3DSA:3.40.50.300 270 449 1.1E-8 T 28-03-2018 SMD44_RS15800 cbe78513818d04fb218778341d1b041b 597 SUPERFAMILY SSF52540 22 182 4.75E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00810 432cef1a7d87c474ef8d48e64f361de5 216 Pfam PF13649 Methyltransferase domain 52 145 3.8E-16 T 28-03-2018 SMD44_RS00810 432cef1a7d87c474ef8d48e64f361de5 216 SUPERFAMILY SSF53335 14 208 3.95E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS00810 432cef1a7d87c474ef8d48e64f361de5 216 Gene3D G3DSA:3.40.50.150 38 212 2.5E-28 T 28-03-2018 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 PRINTS PR00996 Glutamate methyltransferase family signature 32 45 6.4E-29 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 PRINTS PR00996 Glutamate methyltransferase family signature 109 129 6.4E-29 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 PRINTS PR00996 Glutamate methyltransferase family signature 145 161 6.4E-29 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 PRINTS PR00996 Glutamate methyltransferase family signature 211 225 6.4E-29 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 PRINTS PR00996 Glutamate methyltransferase family signature 69 81 6.4E-29 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 PRINTS PR00996 Glutamate methyltransferase family signature 230 253 6.4E-29 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 SUPERFAMILY SSF53335 76 268 5.09E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Gene3D G3DSA:3.30.450.20 287 434 9.6E-12 T 28-03-2018 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Gene3D G3DSA:1.20.5.170 435 461 0.38 T 28-03-2018 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Gene3D G3DSA:3.40.50.150 75 273 1.6E-46 T 28-03-2018 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 SMART SM00091 304 369 1.6 T 28-03-2018 IPR000014 PAS domain SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 SMART SM00091 506 575 0.017 T 28-03-2018 IPR000014 PAS domain SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Pfam PF01739 CheR methyltransferase, SAM binding domain 76 267 1.2E-56 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Pfam PF13596 PAS domain 308 415 2.8E-6 T 28-03-2018 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 SUPERFAMILY SSF55785 297 415 3.24E-8 T 28-03-2018 IPR000014 PAS domain SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Gene3D G3DSA:1.10.155.10 6 73 1.1E-10 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 SMART SM00138 10 271 2.6E-81 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Gene3D G3DSA:3.30.450.20 496 614 4.1E-15 T 28-03-2018 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 SUPERFAMILY SSF55785 494 609 4.0E-12 T 28-03-2018 IPR000014 PAS domain SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Gene3D G3DSA:3.40.50.150 462 495 1.6E-7 T 28-03-2018 SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 505 609 1.7E-8 T 28-03-2018 IPR000014 PAS domain SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 SUPERFAMILY SSF47757 8 78 1.14E-10 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Pfam PF03705 CheR methyltransferase, all-alpha domain 13 61 2.6E-11 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal SMD44_RS21380 6c1f07108cadf3a56a04033fefe363bb 621 Pfam PF00989 PAS fold 507 612 3.1E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 SMD44_RS25210 71a4fd00d6e06d1434ca97d52103d184 291 SMART SM00342 191 274 2.9E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS25210 71a4fd00d6e06d1434ca97d52103d184 291 SUPERFAMILY SSF46689 227 277 1.26E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS25210 71a4fd00d6e06d1434ca97d52103d184 291 Gene3D G3DSA:1.10.10.60 231 286 9.1E-11 T 28-03-2018 SMD44_RS25210 71a4fd00d6e06d1434ca97d52103d184 291 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 228 270 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS25210 71a4fd00d6e06d1434ca97d52103d184 291 SUPERFAMILY SSF46689 175 225 7.09E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS25210 71a4fd00d6e06d1434ca97d52103d184 291 Gene3D G3DSA:1.10.10.60 138 230 1.3E-8 T 28-03-2018 SMD44_RS25210 71a4fd00d6e06d1434ca97d52103d184 291 Pfam PF12833 Helix-turn-helix domain 197 275 1.2E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS25210 71a4fd00d6e06d1434ca97d52103d184 291 Pfam PF12852 Cupin 2 159 2.6E-32 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMD44_RS27410 c89ffd1602330d6822ca23621f9f9125 126 Gene3D G3DSA:1.10.10.10 16 118 1.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27410 c89ffd1602330d6822ca23621f9f9125 126 Pfam PF01638 HxlR-like helix-turn-helix 18 107 6.2E-33 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS27410 c89ffd1602330d6822ca23621f9f9125 126 SUPERFAMILY SSF46785 7 111 4.01E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 SUPERFAMILY SSF51735 4 253 1.46E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 Gene3D G3DSA:3.40.50.720 49 261 1.3E-62 T 28-03-2018 SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 Gene3D G3DSA:3.40.50.720 1 48 4.4E-10 T 28-03-2018 SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 9.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 9.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 9.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 4.2E-59 T 28-03-2018 SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 182 3.0E-4 T 28-03-2018 SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41830 76556f3964d91fb01e9ac6232c2537da 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS14455 c039814287fa25a26e8f12a7d69f31e5 393 SUPERFAMILY SSF53067 92 385 4.48E-38 T 28-03-2018 SMD44_RS14455 c039814287fa25a26e8f12a7d69f31e5 393 Pfam PF12802 MarR family 26 70 1.8E-8 T 28-03-2018 SMD44_RS14455 c039814287fa25a26e8f12a7d69f31e5 393 Gene3D G3DSA:3.30.420.40 89 214 1.8E-23 T 28-03-2018 SMD44_RS14455 c039814287fa25a26e8f12a7d69f31e5 393 Gene3D G3DSA:3.30.420.40 215 393 1.5E-49 T 28-03-2018 SMD44_RS14455 c039814287fa25a26e8f12a7d69f31e5 393 SMART SM00418 18 99 8.2E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS14455 c039814287fa25a26e8f12a7d69f31e5 393 Pfam PF00480 ROK family 127 341 3.1E-29 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS14455 c039814287fa25a26e8f12a7d69f31e5 393 Gene3D G3DSA:1.10.10.10 15 88 2.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14455 c039814287fa25a26e8f12a7d69f31e5 393 SUPERFAMILY SSF46785 21 86 1.45E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07595 950404782a480a5c07cbca620736f6c2 401 PRINTS PR00095 Anthranilate synthase component I signature 305 319 1.0E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS07595 950404782a480a5c07cbca620736f6c2 401 PRINTS PR00095 Anthranilate synthase component I signature 209 222 1.0E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS07595 950404782a480a5c07cbca620736f6c2 401 PRINTS PR00095 Anthranilate synthase component I signature 289 303 1.0E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS07595 950404782a480a5c07cbca620736f6c2 401 Pfam PF00425 chorismate binding enzyme 102 350 1.6E-71 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMD44_RS07595 950404782a480a5c07cbca620736f6c2 401 SUPERFAMILY SSF56322 69 357 4.97E-91 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS07595 950404782a480a5c07cbca620736f6c2 401 Gene3D G3DSA:3.60.120.10 36 364 3.1E-98 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS35200 c4d142db4df8b5e954f812a25c68f22c 154 Gene3D G3DSA:1.10.10.10 1 154 5.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35200 c4d142db4df8b5e954f812a25c68f22c 154 SUPERFAMILY SSF46785 5 143 2.59E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35200 c4d142db4df8b5e954f812a25c68f22c 154 SMART SM00347 26 126 2.5E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS35200 c4d142db4df8b5e954f812a25c68f22c 154 Pfam PF13463 Winged helix DNA-binding domain 34 99 5.8E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS15380 bf19e46d6634c175ce4be6c7f956680f 358 Gene3D G3DSA:3.40.190.10 37 173 1.4E-27 T 28-03-2018 SMD44_RS15380 bf19e46d6634c175ce4be6c7f956680f 358 SUPERFAMILY SSF53850 36 352 5.65E-59 T 28-03-2018 SMD44_RS15380 bf19e46d6634c175ce4be6c7f956680f 358 PIRSF PIRSF002825 7 356 2.9E-51 T 28-03-2018 IPR026045 Ferric binding protein SMD44_RS15380 bf19e46d6634c175ce4be6c7f956680f 358 Pfam PF13343 Bacterial extracellular solute-binding protein 93 344 3.4E-30 T 28-03-2018 SMD44_RS15380 bf19e46d6634c175ce4be6c7f956680f 358 Gene3D G3DSA:3.40.190.10 174 333 4.3E-13 T 28-03-2018 SMD44_RS26335 13e5ced2850142d5f64baa940fcbaa85 131 Gene3D G3DSA:3.30.1330.40 3 131 8.4E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS26335 13e5ced2850142d5f64baa940fcbaa85 131 Pfam PF01042 Endoribonuclease L-PSP 26 130 1.9E-17 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS26335 13e5ced2850142d5f64baa940fcbaa85 131 SUPERFAMILY SSF55298 15 130 3.14E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS36925 206427c2c5e1a26e3258ef10d22cd43c 249 SMART SM00824 Thioesterase 25 247 8.2E-4 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD44_RS36925 206427c2c5e1a26e3258ef10d22cd43c 249 SUPERFAMILY SSF53474 6 246 6.4E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36925 206427c2c5e1a26e3258ef10d22cd43c 249 Gene3D G3DSA:3.40.50.1820 2 249 3.7E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36925 206427c2c5e1a26e3258ef10d22cd43c 249 Pfam PF00975 Thioesterase domain 23 241 3.9E-61 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 SUPERFAMILY SSF53187 19 199 3.14E-53 T 28-03-2018 SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 SUPERFAMILY SSF53187 357 444 3.14E-53 T 28-03-2018 SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 89 98 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 Pfam PF01546 Peptidase family M20/M25/M40 90 445 7.2E-37 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 PIRSF PIRSF036696 290 447 7.1E-6 T 28-03-2018 SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 PIRSF PIRSF036696 13 259 5.5E-35 T 28-03-2018 SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 Gene3D G3DSA:3.40.630.10 13 213 5.7E-44 T 28-03-2018 SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 Pfam PF07687 Peptidase dimerisation domain 207 335 7.0E-15 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 SUPERFAMILY SSF55031 211 254 4.06E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 SUPERFAMILY SSF55031 298 336 4.06E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS08365 cfb4a7eb24e76faed11b87bfff1e71aa 447 Gene3D G3DSA:3.30.70.360 214 358 3.4E-23 T 28-03-2018 SMD44_RS32930 be2ff83938f9b92da37fac7bd3c1e898 360 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 26 326 30.936 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SMD44_RS32930 be2ff83938f9b92da37fac7bd3c1e898 360 Gene3D G3DSA:3.40.50.300 100 262 1.4E-24 T 28-03-2018 SMD44_RS32930 be2ff83938f9b92da37fac7bd3c1e898 360 SUPERFAMILY SSF52540 105 323 3.99E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32930 be2ff83938f9b92da37fac7bd3c1e898 360 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 84 319 3.7E-45 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SMD44_RS32930 be2ff83938f9b92da37fac7bd3c1e898 360 Gene3D G3DSA:1.10.40.50 266 330 7.1E-20 T 28-03-2018 SMD44_RS32930 be2ff83938f9b92da37fac7bd3c1e898 360 Pfam PF03193 RsgA GTPase 87 262 1.4E-45 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 SMD44_RS14015 8c1b7b51e1b2e11766e020436b75a341 1452 SMART SM00316 702 781 1.6E-4 T 28-03-2018 IPR022967 RNA-binding domain, S1 SMD44_RS14015 8c1b7b51e1b2e11766e020436b75a341 1452 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 679 1081 1.9E-152 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 SMD44_RS14015 8c1b7b51e1b2e11766e020436b75a341 1452 Pfam PF10150 Ribonuclease E/G family 783 1054 9.0E-107 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 SMD44_RS14015 8c1b7b51e1b2e11766e020436b75a341 1452 SUPERFAMILY SSF50249 704 787 5.03E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS14015 8c1b7b51e1b2e11766e020436b75a341 1452 Gene3D G3DSA:2.40.50.140 697 786 2.1E-25 T 28-03-2018 SMD44_RS27000 6f6a9ddce924c887f9820e819baf7282 263 Gene3D G3DSA:1.10.12.10 222 263 1.0E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal SMD44_RS27000 6f6a9ddce924c887f9820e819baf7282 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 261 1.5E-58 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS27000 6f6a9ddce924c887f9820e819baf7282 263 SUPERFAMILY SSF52096 8 263 2.72E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS27000 6f6a9ddce924c887f9820e819baf7282 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD44_RS27000 6f6a9ddce924c887f9820e819baf7282 263 Gene3D G3DSA:3.90.226.10 9 221 9.9E-71 T 28-03-2018 SMD44_RS14350 516ae1897db3c67aa079d6b4131b2ebc 283 SMART SM00530 17 72 2.9E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS14350 516ae1897db3c67aa079d6b4131b2ebc 283 Pfam PF13560 Helix-turn-helix domain 13 72 6.2E-12 T 28-03-2018 SMD44_RS14350 516ae1897db3c67aa079d6b4131b2ebc 283 Gene3D G3DSA:1.10.260.40 5 86 1.6E-12 T 28-03-2018 SMD44_RS14350 516ae1897db3c67aa079d6b4131b2ebc 283 SUPERFAMILY SSF47413 12 74 1.04E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 SUPERFAMILY SSF55979 2 119 1.14E-23 T 28-03-2018 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 246 2.4E-32 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 8.5E-90 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 Gene3D G3DSA:3.10.150.10 122 250 9.1E-32 T 28-03-2018 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 SUPERFAMILY SSF55979 249 374 1.96E-29 T 28-03-2018 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 Gene3D G3DSA:3.10.150.10 251 374 1.1E-30 T 28-03-2018 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 2.2E-38 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 PIRSF PIRSF000804 1 375 6.8E-94 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 Gene3D G3DSA:3.10.150.10 1 121 9.2E-33 T 28-03-2018 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 373 1.0E-35 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 SUPERFAMILY SSF55979 126 247 3.93E-18 T 28-03-2018 SMD44_RS21130 e28cf51ed8b419d783706a52acfedcb4 376 SMART SM00480 17 370 1.1E-142 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 PIRSF PIRSF005303 3 315 1.7E-89 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 315 3.1E-84 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 Gene3D G3DSA:3.90.650.10 151 315 3.0E-43 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 Gene3D G3DSA:3.30.1330.10 1 148 5.4E-36 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 SUPERFAMILY SSF55326 5 142 1.94E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 245 2.0E-5 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 SUPERFAMILY SSF56042 148 295 7.67E-33 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 142 1.2E-21 T 28-03-2018 IPR016188 PurM-like, N-terminal domain SMD44_RS30300 3cd6a31b6294843c8ffa2a8a6213fb0c 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 312 28.667 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMD44_RS41875 460ed068b0bbc47678ebe26321e98847 146 Gene3D G3DSA:3.10.180.10 1 146 3.5E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS41875 460ed068b0bbc47678ebe26321e98847 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 118 1.4E-10 T 28-03-2018 SMD44_RS41875 460ed068b0bbc47678ebe26321e98847 146 SUPERFAMILY SSF54593 3 143 1.2E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 SUPERFAMILY SSF52317 7 201 2.45E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 Gene3D G3DSA:1.10.10.60 237 276 1.5E-12 T 28-03-2018 SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 SUPERFAMILY SSF46689 224 269 1.91E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 Gene3D G3DSA:3.40.50.880 2 236 5.1E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 SUPERFAMILY SSF46689 272 322 1.61E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 Gene3D G3DSA:1.10.10.60 277 329 1.1E-9 T 28-03-2018 SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 SMART SM00342 235 318 1.7E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 Pfam PF01965 DJ-1/PfpI family 7 180 8.2E-14 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS29785 de18d88e2f62fef0ac35e6dbb6e1cde2 337 Pfam PF12833 Helix-turn-helix domain 241 319 3.3E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS37135 81035e5678df4ba76f22e372c76dc3c5 315 SUPERFAMILY SSF160964 34 64 8.63E-6 T 28-03-2018 SMD44_RS37135 81035e5678df4ba76f22e372c76dc3c5 315 Gene3D G3DSA:1.20.58.370 16 64 2.9E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMD44_RS37135 81035e5678df4ba76f22e372c76dc3c5 315 Gene3D G3DSA:1.10.3720.10 83 313 2.8E-41 T 28-03-2018 SMD44_RS37135 81035e5678df4ba76f22e372c76dc3c5 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 307 5.3E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS37135 81035e5678df4ba76f22e372c76dc3c5 315 SUPERFAMILY SSF161098 76 305 1.96E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS35515 377552385ff4de8c93ae17feb1d1d9b5 468 Gene3D G3DSA:3.50.50.60 1 462 1.0E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS35515 377552385ff4de8c93ae17feb1d1d9b5 468 PRINTS PR00757 Flavin-containing amine oxidase signature 434 451 2.1E-6 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS35515 377552385ff4de8c93ae17feb1d1d9b5 468 PRINTS PR00757 Flavin-containing amine oxidase signature 20 39 2.1E-6 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS35515 377552385ff4de8c93ae17feb1d1d9b5 468 SUPERFAMILY SSF51905 18 321 3.89E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS35515 377552385ff4de8c93ae17feb1d1d9b5 468 SUPERFAMILY SSF51905 413 454 3.89E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS35515 377552385ff4de8c93ae17feb1d1d9b5 468 Pfam PF01593 Flavin containing amine oxidoreductase 28 452 3.7E-45 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS35515 377552385ff4de8c93ae17feb1d1d9b5 468 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 22 453 2.5E-137 T 28-03-2018 IPR017830 Squalene-associated FAD-dependent desaturase SMD44_RS35235 fe22a9535e5d5e5a86329ca080387118 371 ProSitePatterns PS00080 Multicopper oxidases signature 2. 290 301 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMD44_RS35235 fe22a9535e5d5e5a86329ca080387118 371 Gene3D G3DSA:2.60.40.420 194 331 4.8E-26 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS35235 fe22a9535e5d5e5a86329ca080387118 371 Pfam PF07732 Multicopper oxidase 76 185 2.4E-12 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD44_RS35235 fe22a9535e5d5e5a86329ca080387118 371 SUPERFAMILY SSF49503 197 318 1.83E-22 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS35235 fe22a9535e5d5e5a86329ca080387118 371 Gene3D G3DSA:2.60.40.420 52 193 1.6E-26 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS35235 fe22a9535e5d5e5a86329ca080387118 371 Pfam PF07731 Multicopper oxidase 204 309 2.7E-12 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMD44_RS35235 fe22a9535e5d5e5a86329ca080387118 371 SUPERFAMILY SSF49503 73 205 5.43E-18 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 Gene3D G3DSA:3.40.50.2300 50 169 1.3E-27 T 28-03-2018 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 SUPERFAMILY SSF53822 59 339 6.48E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 Gene3D G3DSA:1.10.260.40 3 49 2.4E-15 T 28-03-2018 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 Pfam PF13377 Periplasmic binding protein-like domain 171 337 1.3E-34 T 28-03-2018 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 2.8E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 SMART SM00354 2 69 4.1E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 Gene3D G3DSA:3.40.50.2300 170 340 1.1E-45 T 28-03-2018 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 7.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 7.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 SUPERFAMILY SSF47413 3 49 8.26E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS11845 4d751d2fc57dec5560bc3a999b997343 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 SMART SM00382 92 388 2.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 15 1315 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 SMART SM00847 468 563 1.6E-37 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 Gene3D G3DSA:3.40.50.300 253 428 4.3E-48 T 28-03-2018 SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 Pfam PF11898 Domain of unknown function (DUF3418) 720 1315 8.2E-227 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 SMART SM00490 305 408 9.3E-14 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 SUPERFAMILY SSF52540 74 605 2.19E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 Pfam PF00270 DEAD/DEAH box helicase 87 233 5.1E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 Pfam PF00271 Helicase conserved C-terminal domain 286 407 3.2E-12 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 Gene3D G3DSA:3.40.50.300 76 235 4.5E-30 T 28-03-2018 SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 SMART SM00487 68 259 6.8E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 Pfam PF04408 Helicase associated domain (HA2) 470 561 1.2E-18 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 SMD44_RS19905 b74b691c1f08bbd8cf1e3cac5f3e332a 1319 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 626 705 1.5E-18 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 SMD44_RS22780 2c53219f71c7930cf5c4cc8280b52799 190 Pfam PF01872 RibD C-terminal domain 2 182 1.2E-34 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS22780 2c53219f71c7930cf5c4cc8280b52799 190 SUPERFAMILY SSF53597 4 186 3.93E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS22780 2c53219f71c7930cf5c4cc8280b52799 190 Gene3D G3DSA:3.40.430.10 3 186 1.0E-27 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS09135 9976957687c0397d085779cbdd300cbd 603 SUPERFAMILY SSF48208 197 596 2.04E-109 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS09135 9976957687c0397d085779cbdd300cbd 603 Gene3D G3DSA:1.50.10.10 194 553 3.7E-101 T 28-03-2018 SMD44_RS09135 9976957687c0397d085779cbdd300cbd 603 Pfam PF00723 Glycosyl hydrolases family 15 223 592 7.2E-73 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 Gene3D G3DSA:3.40.50.720 45 248 8.9E-57 T 28-03-2018 SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 Gene3D G3DSA:3.40.50.720 1 44 9.2E-10 T 28-03-2018 SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 SUPERFAMILY SSF51735 6 247 8.27E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 5.8E-55 T 28-03-2018 SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 0.0014 T 28-03-2018 SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS30670 f1edcfe2e5b18a0fa8efe641d188dc91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25255 4c8ecdd294f49533fbfcef45433fc259 371 SUPERFAMILY SSF55874 260 365 2.74E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS25255 4c8ecdd294f49533fbfcef45433fc259 371 Pfam PF07730 Histidine kinase 179 244 8.4E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS25255 4c8ecdd294f49533fbfcef45433fc259 371 Gene3D G3DSA:3.30.565.10 241 371 2.8E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS25255 4c8ecdd294f49533fbfcef45433fc259 371 Pfam PF13796 Putative sensor 9 128 5.7E-31 T 28-03-2018 IPR025828 Putative sensor domain SMD44_RS33960 196f9da260b9c129b3b9794c7b24c0c8 83 Gene3D G3DSA:1.10.260.40 35 80 2.4E-8 T 28-03-2018 SMD44_RS33960 196f9da260b9c129b3b9794c7b24c0c8 83 SUPERFAMILY SSF47413 7 74 3.1E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS33960 196f9da260b9c129b3b9794c7b24c0c8 83 SMART SM00530 20 74 1.8E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS33960 196f9da260b9c129b3b9794c7b24c0c8 83 Pfam PF13560 Helix-turn-helix domain 16 76 8.1E-12 T 28-03-2018 SMD44_RS33960 196f9da260b9c129b3b9794c7b24c0c8 83 Gene3D G3DSA:1.10.10.10 3 34 3.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 PRINTS PR00364 Disease resistance protein signature 292 306 2.3E-7 T 28-03-2018 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 PRINTS PR00364 Disease resistance protein signature 125 140 2.3E-7 T 28-03-2018 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 PRINTS PR00364 Disease resistance protein signature 204 218 2.3E-7 T 28-03-2018 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 SMART SM00530 19 74 1.7E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 Gene3D G3DSA:3.40.50.300 89 248 4.2E-18 T 28-03-2018 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 Pfam PF13560 Helix-turn-helix domain 15 75 6.6E-16 T 28-03-2018 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 Gene3D G3DSA:1.10.260.40 13 81 1.1E-14 T 28-03-2018 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 SUPERFAMILY SSF47413 16 68 8.73E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 Pfam PF00931 NB-ARC domain 121 367 1.6E-8 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS01980 0f1b4bd291c610b5302e9831ce584172 475 SUPERFAMILY SSF52540 87 363 2.94E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS02205 66f8ed8c02fd1f62fda85c5ead3bea44 338 Gene3D G3DSA:1.10.10.60 221 280 3.1E-10 T 28-03-2018 SMD44_RS02205 66f8ed8c02fd1f62fda85c5ead3bea44 338 Gene3D G3DSA:1.10.10.60 148 220 4.6E-5 T 28-03-2018 SMD44_RS02205 66f8ed8c02fd1f62fda85c5ead3bea44 338 Pfam PF12833 Helix-turn-helix domain 189 265 5.8E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS02205 66f8ed8c02fd1f62fda85c5ead3bea44 338 SMART SM00342 183 265 1.8E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS02205 66f8ed8c02fd1f62fda85c5ead3bea44 338 SUPERFAMILY SSF46689 219 264 1.34E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 ProSitePatterns PS01071 grpE protein signature. 149 192 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 PRINTS PR00773 GrpE protein signature 173 192 6.2E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 PRINTS PR00773 GrpE protein signature 71 87 6.2E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 PRINTS PR00773 GrpE protein signature 99 114 6.2E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 PRINTS PR00773 GrpE protein signature 146 161 6.2E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 SUPERFAMILY SSF51064 140 195 6.02E-16 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 Hamap MF_01151 Protein GrpE [grpE]. 3 194 17.309 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 Pfam PF01025 GrpE 47 194 4.2E-34 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 Gene3D G3DSA:2.30.22.10 141 200 1.5E-21 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 Gene3D G3DSA:3.90.20.20 42 140 2.0E-16 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 SMD44_RS22475 0fb615891663350a20fb6519b0fdc492 242 SUPERFAMILY SSF58014 52 138 7.59E-17 T 28-03-2018 SMD44_RS42905 7b5fb78e598b61fc6a1fd79d08e3d757 261 Gene3D G3DSA:3.40.50.150 1 261 1.3E-53 T 28-03-2018 SMD44_RS42905 7b5fb78e598b61fc6a1fd79d08e3d757 261 SUPERFAMILY SSF53335 10 245 4.38E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS42905 7b5fb78e598b61fc6a1fd79d08e3d757 261 Pfam PF04672 S-adenosyl methyltransferase 3 260 1.9E-108 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS42905 7b5fb78e598b61fc6a1fd79d08e3d757 261 PIRSF PIRSF017393 1 261 9.8E-99 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS15395 12a765bbe529c9e0458e3b5465934ca3 350 SUPERFAMILY SSF50331 239 343 9.23E-13 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMD44_RS15395 12a765bbe529c9e0458e3b5465934ca3 350 Pfam PF08402 TOBE domain 273 343 1.1E-12 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMD44_RS15395 12a765bbe529c9e0458e3b5465934ca3 350 Gene3D G3DSA:2.40.50.140 276 336 1.5E-6 T 28-03-2018 SMD44_RS15395 12a765bbe529c9e0458e3b5465934ca3 350 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS15395 12a765bbe529c9e0458e3b5465934ca3 350 Pfam PF00005 ABC transporter 20 162 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS15395 12a765bbe529c9e0458e3b5465934ca3 350 SMART SM00382 29 213 1.3E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS15395 12a765bbe529c9e0458e3b5465934ca3 350 Gene3D G3DSA:3.40.50.300 1 244 2.5E-71 T 28-03-2018 SMD44_RS15395 12a765bbe529c9e0458e3b5465934ca3 350 SUPERFAMILY SSF52540 5 244 2.54E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS05130 0c2476ea8f3132b2fa2f4e7d85a30ed3 255 Gene3D G3DSA:3.30.450.40 69 255 1.2E-53 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS05130 0c2476ea8f3132b2fa2f4e7d85a30ed3 255 SMART SM00346 1 91 4.0E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS05130 0c2476ea8f3132b2fa2f4e7d85a30ed3 255 SUPERFAMILY SSF46785 1 72 1.16E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05130 0c2476ea8f3132b2fa2f4e7d85a30ed3 255 Pfam PF01614 Bacterial transcriptional regulator 119 242 4.2E-31 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS05130 0c2476ea8f3132b2fa2f4e7d85a30ed3 255 Gene3D G3DSA:1.10.10.10 5 66 5.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05130 0c2476ea8f3132b2fa2f4e7d85a30ed3 255 Pfam PF09339 IclR helix-turn-helix domain 6 52 9.2E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS05130 0c2476ea8f3132b2fa2f4e7d85a30ed3 255 SUPERFAMILY SSF55781 75 246 2.62E-50 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS08755 e6866d4782c46bce5bf6142e776095c9 168 Gene3D G3DSA:2.40.380.10 10 168 4.8E-33 T 28-03-2018 IPR007295 Domain of unknown function DUF402 SMD44_RS08755 e6866d4782c46bce5bf6142e776095c9 168 SUPERFAMILY SSF159234 55 154 4.05E-16 T 28-03-2018 IPR007295 Domain of unknown function DUF402 SMD44_RS08755 e6866d4782c46bce5bf6142e776095c9 168 Pfam PF04167 Protein of unknown function (DUF402) 64 131 2.3E-19 T 28-03-2018 IPR007295 Domain of unknown function DUF402 SMD44_RS42710 30c71436c21b391224f650f00caa1754 214 Gene3D G3DSA:3.40.30.10 11 67 1.7E-8 T 28-03-2018 SMD44_RS42710 30c71436c21b391224f650f00caa1754 214 SUPERFAMILY SSF52833 15 174 2.46E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS42710 30c71436c21b391224f650f00caa1754 214 Gene3D G3DSA:3.40.30.10 68 177 1.1E-8 T 28-03-2018 SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 PRINTS PR00834 HtrA/DegQ protease family signature 274 291 4.1E-27 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 PRINTS PR00834 HtrA/DegQ protease family signature 142 154 4.1E-27 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 PRINTS PR00834 HtrA/DegQ protease family signature 296 313 4.1E-27 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 PRINTS PR00834 HtrA/DegQ protease family signature 163 183 4.1E-27 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 SUPERFAMILY SSF50494 109 236 4.94E-52 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 SUPERFAMILY SSF50494 272 345 4.94E-52 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 Pfam PF13365 Trypsin-like peptidase domain 133 303 5.8E-31 T 28-03-2018 SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 Gene3D G3DSA:2.40.10.10 103 199 1.8E-33 T 28-03-2018 SMD44_RS19310 1a888db921e2c4a63d5c7f2eace1edc7 349 Gene3D G3DSA:2.40.10.10 200 342 5.0E-35 T 28-03-2018 SMD44_RS32675 f147d7ffc9c88100374eb190fabc5c95 180 Pfam PF00498 FHA domain 108 171 8.3E-17 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS32675 f147d7ffc9c88100374eb190fabc5c95 180 Gene3D G3DSA:2.60.200.20 4 179 1.0E-20 T 28-03-2018 SMD44_RS32675 f147d7ffc9c88100374eb190fabc5c95 180 Pfam PF08044 Domain of unknown function (DUF1707) 10 61 9.5E-15 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 SMD44_RS32675 f147d7ffc9c88100374eb190fabc5c95 180 SMART SM00240 106 156 8.1E-14 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS32675 f147d7ffc9c88100374eb190fabc5c95 180 SUPERFAMILY SSF49879 104 176 8.61E-23 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS04215 c2f401da902b700de8bafa6987430367 225 Gene3D G3DSA:1.10.150.240 20 72 5.5E-5 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS04215 c2f401da902b700de8bafa6987430367 225 Gene3D G3DSA:3.40.50.1000 73 224 1.9E-23 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS04215 c2f401da902b700de8bafa6987430367 225 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 176 4.5E-18 T 28-03-2018 SMD44_RS04215 c2f401da902b700de8bafa6987430367 225 SUPERFAMILY SSF56784 1 213 2.62E-34 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS14865 d6c5d9a6fdc679f120817bcb174e2758 570 SUPERFAMILY SSF52279 381 560 2.48E-18 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMD44_RS14865 d6c5d9a6fdc679f120817bcb174e2758 570 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 263 280 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 SMD44_RS14865 d6c5d9a6fdc679f120817bcb174e2758 570 Gene3D G3DSA:3.20.20.300 1 366 4.6E-100 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS14865 d6c5d9a6fdc679f120817bcb174e2758 570 SUPERFAMILY SSF51445 1 378 8.42E-100 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS14865 d6c5d9a6fdc679f120817bcb174e2758 570 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 2 342 7.7E-106 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS14865 d6c5d9a6fdc679f120817bcb174e2758 570 Gene3D G3DSA:3.40.50.1700 367 546 1.9E-21 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMD44_RS14865 d6c5d9a6fdc679f120817bcb174e2758 570 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 381 560 1.7E-15 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMD44_RS12860 c6342e6b5c72bd553d06b7e6d02a3808 391 Gene3D G3DSA:3.40.50.2000 206 362 5.9E-34 T 28-03-2018 SMD44_RS12860 c6342e6b5c72bd553d06b7e6d02a3808 391 SUPERFAMILY SSF53756 29 373 3.49E-62 T 28-03-2018 SMD44_RS12860 c6342e6b5c72bd553d06b7e6d02a3808 391 Gene3D G3DSA:3.40.50.2000 25 205 1.4E-7 T 28-03-2018 SMD44_RS12860 c6342e6b5c72bd553d06b7e6d02a3808 391 Pfam PF13439 Glycosyltransferase Family 4 43 198 2.8E-17 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS12860 c6342e6b5c72bd553d06b7e6d02a3808 391 Pfam PF00534 Glycosyl transferases group 1 205 356 2.2E-25 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS06270 a13d7b5478122d2554b210b9303fb813 257 SUPERFAMILY SSF51161 56 210 2.08E-36 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS06270 a13d7b5478122d2554b210b9303fb813 257 Gene3D G3DSA:2.160.10.10 100 216 3.6E-32 T 28-03-2018 SMD44_RS06270 a13d7b5478122d2554b210b9303fb813 257 Gene3D G3DSA:2.160.10.10 13 99 1.4E-4 T 28-03-2018 SMD44_RS06270 a13d7b5478122d2554b210b9303fb813 257 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 156 190 5.1E-10 T 28-03-2018 IPR001451 Hexapeptide repeat SMD44_RS06270 a13d7b5478122d2554b210b9303fb813 257 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 99 133 3.6E-4 T 28-03-2018 IPR001451 Hexapeptide repeat SMD44_RS06270 a13d7b5478122d2554b210b9303fb813 257 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 164 192 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SMD44_RS16395 e1eddb3f33482afc7ff5bd86ad82530f 58 Gene3D G3DSA:2.20.25.10 10 57 3.0E-21 T 28-03-2018 SMD44_RS16395 e1eddb3f33482afc7ff5bd86ad82530f 58 SUPERFAMILY SSF158997 1 56 1.26E-15 T 28-03-2018 SMD44_RS16395 e1eddb3f33482afc7ff5bd86ad82530f 58 Pfam PF03966 Trm112p-like protein 7 45 6.7E-7 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 SMD44_RS26505 1b3039e674780442e8a6c818d423800d 223 Pfam PF08281 Sigma-70, region 4 103 150 1.9E-6 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26505 1b3039e674780442e8a6c818d423800d 223 Gene3D G3DSA:1.10.1740.10 1 65 9.3E-14 T 28-03-2018 SMD44_RS26505 1b3039e674780442e8a6c818d423800d 223 Pfam PF04542 Sigma-70 region 2 5 66 1.3E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26505 1b3039e674780442e8a6c818d423800d 223 Gene3D G3DSA:1.10.10.10 66 157 1.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26505 1b3039e674780442e8a6c818d423800d 223 SUPERFAMILY SSF88659 98 154 5.23E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26505 1b3039e674780442e8a6c818d423800d 223 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 154 1.8E-13 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26505 1b3039e674780442e8a6c818d423800d 223 SUPERFAMILY SSF88946 2 82 2.75E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 Gene3D G3DSA:3.30.450.20 52 159 0.0017 T 28-03-2018 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 SUPERFAMILY SSF55874 211 396 7.73E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 219 1.9E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 SMART SM00388 155 221 6.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 SMART SM00387 282 398 1.6E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 396 4.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 Gene3D G3DSA:1.10.287.130 160 217 7.5E-14 T 28-03-2018 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 395 1.5E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 337 1.5E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 351 1.5E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 376 1.5E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 Gene3D G3DSA:3.30.565.10 225 407 7.3E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19030 13a8ea5567ee468a6fedca5af301acd1 436 SUPERFAMILY SSF47384 138 221 2.75E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS01860 5cdd1313779b992178911112200a9151 281 Gene3D G3DSA:3.90.226.10 27 279 1.0E-67 T 28-03-2018 SMD44_RS01860 5cdd1313779b992178911112200a9151 281 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 124 144 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD44_RS01860 5cdd1313779b992178911112200a9151 281 SUPERFAMILY SSF52096 32 277 6.12E-70 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS01860 5cdd1313779b992178911112200a9151 281 Pfam PF00378 Enoyl-CoA hydratase/isomerase 40 273 7.7E-49 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 Pfam PF01642 Methylmalonyl-CoA mutase 42 560 8.1E-234 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 384 409 - T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 Gene3D G3DSA:3.20.20.240 41 562 4.6E-243 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 41 567 6.5E-279 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 599 725 3.1E-61 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 SUPERFAMILY SSF51703 21 562 1.67E-220 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 Pfam PF02310 B12 binding domain 602 712 9.0E-14 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 Gene3D G3DSA:3.40.50.280 584 727 3.5E-39 T 28-03-2018 SMD44_RS05990 63e4e9c434715431187995435bc6a35c 744 SUPERFAMILY SSF52242 565 725 1.7E-57 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS33540 a57d3aa5565fd9aa17d8812aecabbe3a 445 Gene3D G3DSA:3.20.20.140 72 413 1.9E-117 T 28-03-2018 SMD44_RS33540 a57d3aa5565fd9aa17d8812aecabbe3a 445 SUPERFAMILY SSF51556 58 373 1.92E-98 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS33540 a57d3aa5565fd9aa17d8812aecabbe3a 445 Gene3D G3DSA:2.30.40.10 5 71 1.5E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS33540 a57d3aa5565fd9aa17d8812aecabbe3a 445 Pfam PF01979 Amidohydrolase family 55 426 9.6E-31 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS33540 a57d3aa5565fd9aa17d8812aecabbe3a 445 TIGRFAM TIGR03178 allantoinase: allantoinase 5 443 9.5E-190 T 28-03-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 SMD44_RS33540 a57d3aa5565fd9aa17d8812aecabbe3a 445 SUPERFAMILY SSF51338 5 57 1.79E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS33540 a57d3aa5565fd9aa17d8812aecabbe3a 445 SUPERFAMILY SSF51338 373 436 1.79E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS09050 29480f9ea0baf7bf8028197b40a73167 361 Gene3D G3DSA:3.40.50.720 1 164 8.3E-25 T 28-03-2018 SMD44_RS09050 29480f9ea0baf7bf8028197b40a73167 361 Gene3D G3DSA:3.30.70.260 293 355 6.5E-5 T 28-03-2018 SMD44_RS09050 29480f9ea0baf7bf8028197b40a73167 361 SUPERFAMILY SSF51735 5 158 5.1E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09050 29480f9ea0baf7bf8028197b40a73167 361 Pfam PF02153 Prephenate dehydrogenase 17 250 1.4E-59 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 SMD44_RS09050 29480f9ea0baf7bf8028197b40a73167 361 Gene3D G3DSA:1.10.3660.10 173 262 4.7E-13 T 28-03-2018 SMD44_RS09050 29480f9ea0baf7bf8028197b40a73167 361 SUPERFAMILY SSF48179 165 251 3.85E-23 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS09790 958d0078dc7a3bef78a4eb96160e0e31 250 Pfam PF02517 CAAX protease self-immunity 146 230 1.2E-6 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SMD44_RS25945 49d66113c15340d5ce1dff5eb15ead14 352 Gene3D G3DSA:3.90.1720.10 232 345 4.8E-38 T 28-03-2018 SMD44_RS25945 49d66113c15340d5ce1dff5eb15ead14 352 Pfam PF00877 NlpC/P60 family 252 342 1.7E-26 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS25945 49d66113c15340d5ce1dff5eb15ead14 352 Gene3D G3DSA:1.20.120.330 40 207 3.6E-10 T 28-03-2018 SMD44_RS25945 49d66113c15340d5ce1dff5eb15ead14 352 SUPERFAMILY SSF54001 234 351 2.01E-43 T 28-03-2018 SMD44_RS00730 abd0857d703e546213757bed209a233a 294 Pfam PF08281 Sigma-70, region 4 114 164 5.8E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00730 abd0857d703e546213757bed209a233a 294 SUPERFAMILY SSF88659 112 168 1.05E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00730 abd0857d703e546213757bed209a233a 294 Gene3D G3DSA:3.10.450.50 157 290 5.4E-15 T 28-03-2018 SMD44_RS00730 abd0857d703e546213757bed209a233a 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 167 9.6E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00730 abd0857d703e546213757bed209a233a 294 Gene3D G3DSA:1.10.1740.10 7 75 3.5E-14 T 28-03-2018 SMD44_RS00730 abd0857d703e546213757bed209a233a 294 SUPERFAMILY SSF54427 180 286 1.14E-13 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS00730 abd0857d703e546213757bed209a233a 294 SUPERFAMILY SSF88946 11 90 5.89E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00730 abd0857d703e546213757bed209a233a 294 Gene3D G3DSA:1.10.10.10 76 156 1.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00730 abd0857d703e546213757bed209a233a 294 Pfam PF04542 Sigma-70 region 2 14 78 2.6E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS32665 b126b94f7b868a47f91fe2cb2c82eb90 63 SUPERFAMILY SSF69047 4 55 1.44E-11 T 28-03-2018 IPR008462 CsbD-like domain SMD44_RS32665 b126b94f7b868a47f91fe2cb2c82eb90 63 Gene3D G3DSA:1.10.1470.10 3 61 2.1E-13 T 28-03-2018 IPR008462 CsbD-like domain SMD44_RS32665 b126b94f7b868a47f91fe2cb2c82eb90 63 Pfam PF05532 CsbD-like 4 52 2.7E-14 T 28-03-2018 IPR008462 CsbD-like domain SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 SUPERFAMILY SSF53850 1 208 5.67E-58 T 28-03-2018 SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 Gene3D G3DSA:3.40.190.10 112 209 1.2E-17 T 28-03-2018 SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 Gene3D G3DSA:3.30.70.120 210 274 4.6E-26 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 1.5E-49 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 Pfam PF01634 ATP phosphoribosyltransferase 49 203 1.0E-39 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 Gene3D G3DSA:3.40.190.10 1 111 2.5E-32 T 28-03-2018 SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 282 31.876 T 28-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 189 281 4.9E-30 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 SUPERFAMILY SSF54913 210 281 2.11E-21 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMD44_RS07000 4a8317040a852e7215d04b0b34fce974 282 Pfam PF08029 HisG, C-terminal domain 207 278 9.0E-26 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 SUPERFAMILY SSF52540 418 635 1.61E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 ProSitePatterns PS01312 SecA family signature. 502 517 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Gene3D G3DSA:3.40.50.300 419 650 2.2E-55 T 28-03-2018 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 837 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Pfam PF07516 SecA Wing and Scaffold domain 634 848 1.7E-66 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Pfam PF07517 SecA DEAD-like domain 5 403 1.0E-124 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 SMART SM00957 4 404 4.6E-280 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Gene3D G3DSA:3.40.50.300 7 279 9.5E-54 T 28-03-2018 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Gene3D G3DSA:3.40.50.300 298 418 8.2E-6 T 28-03-2018 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 PRINTS PR00906 SecA protein signature 168 188 5.4E-64 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 PRINTS PR00906 SecA protein signature 115 125 5.4E-64 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 PRINTS PR00906 SecA protein signature 368 385 5.4E-64 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 PRINTS PR00906 SecA protein signature 331 353 5.4E-64 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 PRINTS PR00906 SecA protein signature 99 113 5.4E-64 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 PRINTS PR00906 SecA protein signature 61 85 5.4E-64 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 PRINTS PR00906 SecA protein signature 415 428 5.4E-64 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 SUPERFAMILY SSF81886 637 861 5.23E-74 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 SUPERFAMILY SSF81767 225 360 7.19E-41 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 SMART SM00958 226 350 3.0E-66 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Pfam PF01043 SecA preprotein cross-linking domain 231 350 1.2E-34 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 SUPERFAMILY SSF52540 4 226 1.08E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 SUPERFAMILY SSF52540 360 417 1.08E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Gene3D G3DSA:1.10.3060.10 651 745 3.2E-28 T 28-03-2018 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Gene3D G3DSA:3.10.450.50 746 947 9.2E-38 T 28-03-2018 SMD44_RS16260 d34af41ecec23bb7dec0f3e5c45df24b 950 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 851 19.716 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD44_RS24505 5276de0d003ccd2f47597195d3e7f122 283 SMART SM00530 19 73 4.9E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS24505 5276de0d003ccd2f47597195d3e7f122 283 SUPERFAMILY SSF47413 14 68 2.67E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS24505 5276de0d003ccd2f47597195d3e7f122 283 Gene3D G3DSA:1.10.3100.10 10 167 7.9E-13 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS24505 5276de0d003ccd2f47597195d3e7f122 283 Pfam PF13560 Helix-turn-helix domain 17 68 9.6E-9 T 28-03-2018 SMD44_RS43325 9c5876b728094d1c4c0bb00255625f1d 146 SUPERFAMILY SSF110857 14 125 2.75E-21 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like SMD44_RS43325 9c5876b728094d1c4c0bb00255625f1d 146 Gene3D G3DSA:3.10.490.10 8 146 3.1E-21 T 28-03-2018 SMD44_RS43325 9c5876b728094d1c4c0bb00255625f1d 146 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 15 123 7.8E-23 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like SMD44_RS27105 5f61e4672e79d26145e488619f6f7b34 173 Pfam PF04545 Sigma-70, region 4 94 139 1.7E-8 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS27105 5f61e4672e79d26145e488619f6f7b34 173 SUPERFAMILY SSF88659 94 140 3.18E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS27105 5f61e4672e79d26145e488619f6f7b34 173 Gene3D G3DSA:1.10.10.10 93 157 8.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25975 ed01133078b9fc71732734d1e468fd5f 138 Pfam PF02310 B12 binding domain 8 121 2.9E-23 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS25975 ed01133078b9fc71732734d1e468fd5f 138 SUPERFAMILY SSF52242 6 134 1.44E-50 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS25975 ed01133078b9fc71732734d1e468fd5f 138 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 8 134 9.1E-50 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS25975 ed01133078b9fc71732734d1e468fd5f 138 Gene3D G3DSA:3.40.50.280 3 138 4.7E-38 T 28-03-2018 SMD44_RS15925 71e1025805ccc483bd5819c450b873c0 449 SUPERFAMILY SSF55205 8 442 3.27E-111 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD44_RS15925 71e1025805ccc483bd5819c450b873c0 449 Gene3D G3DSA:3.65.10.10 231 442 1.1E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS15925 71e1025805ccc483bd5819c450b873c0 449 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 9 441 4.8E-132 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS15925 71e1025805ccc483bd5819c450b873c0 449 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 7 443 35.56 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS15925 71e1025805ccc483bd5819c450b873c0 449 Gene3D G3DSA:3.65.10.10 27 230 3.3E-39 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS15925 71e1025805ccc483bd5819c450b873c0 449 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 433 2.2E-58 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS01505 f4ca8419b4303bb4bc42a52d0ea53a5d 447 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 156 173 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 SMD44_RS01505 f4ca8419b4303bb4bc42a52d0ea53a5d 447 Gene3D G3DSA:3.40.190.10 169 372 7.4E-39 T 28-03-2018 SMD44_RS01505 f4ca8419b4303bb4bc42a52d0ea53a5d 447 Gene3D G3DSA:3.40.190.10 49 168 5.6E-19 T 28-03-2018 SMD44_RS01505 f4ca8419b4303bb4bc42a52d0ea53a5d 447 Pfam PF01547 Bacterial extracellular solute-binding protein 60 341 4.8E-35 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS01505 f4ca8419b4303bb4bc42a52d0ea53a5d 447 SUPERFAMILY SSF53850 51 433 1.09E-67 T 28-03-2018 SMD44_RS27615 041db3abb6f1df386009987a776da562 250 SMART SM00866 98 242 2.0E-10 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS27615 041db3abb6f1df386009987a776da562 250 Gene3D G3DSA:1.10.10.10 3 73 5.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27615 041db3abb6f1df386009987a776da562 250 SUPERFAMILY SSF64288 59 248 9.42E-22 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS27615 041db3abb6f1df386009987a776da562 250 SUPERFAMILY SSF46785 4 82 7.14E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27615 041db3abb6f1df386009987a776da562 250 SMART SM00345 12 71 2.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS27615 041db3abb6f1df386009987a776da562 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 2.6E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS27615 041db3abb6f1df386009987a776da562 250 Gene3D G3DSA:3.40.1410.10 77 245 2.5E-31 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS27615 041db3abb6f1df386009987a776da562 250 Pfam PF07702 UTRA domain 111 242 3.3E-11 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS06265 e8207d2a4cf7c4185c124e39bbad38a5 288 SUPERFAMILY SSF103481 211 287 7.45E-9 T 28-03-2018 SMD44_RS06265 e8207d2a4cf7c4185c124e39bbad38a5 288 Pfam PF00892 EamA-like transporter family 3 129 3.8E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS06265 e8207d2a4cf7c4185c124e39bbad38a5 288 Pfam PF00892 EamA-like transporter family 144 286 1.9E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS06265 e8207d2a4cf7c4185c124e39bbad38a5 288 SUPERFAMILY SSF103481 39 134 6.02E-8 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 Pfam PF00702 haloacid dehalogenase-like hydrolase 310 568 1.9E-20 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 Gene3D G3DSA:2.70.150.10 18 212 1.6E-26 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 Gene3D G3DSA:1.20.1110.10 477 798 4.4E-51 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 Gene3D G3DSA:3.40.1110.10 274 468 1.7E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 334 6.8E-30 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 518 635 9.6E-27 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 554 570 2.6E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 585 610 2.6E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 417 435 2.6E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 SUPERFAMILY SSF81660 320 443 1.06E-7 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 577 589 3.7E-22 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 163 177 3.7E-22 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 573 3.7E-22 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 314 328 3.7E-22 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 476 486 3.7E-22 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 SUPERFAMILY SSF56784 414 634 1.06E-36 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 SUPERFAMILY SSF56784 312 332 1.06E-36 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 Pfam PF00122 E1-E2 ATPase 116 294 4.7E-37 T 28-03-2018 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 SUPERFAMILY SSF81665 22 116 1.83E-62 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 SUPERFAMILY SSF81665 214 308 1.83E-62 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 SUPERFAMILY SSF81665 603 797 1.83E-62 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 SUPERFAMILY SSF81653 118 210 2.22E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMD44_RS18545 1d0a8835170bf0e71e3249c7b4c52304 800 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 316 322 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD44_RS03630 863f87511f7e370b6fa016c66790285d 317 Gene3D G3DSA:3.40.50.620 174 317 6.7E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS03630 863f87511f7e370b6fa016c66790285d 317 SUPERFAMILY SSF52402 178 315 8.37E-21 T 28-03-2018 SMD44_RS03630 863f87511f7e370b6fa016c66790285d 317 SUPERFAMILY SSF52402 27 159 1.26E-18 T 28-03-2018 SMD44_RS03630 863f87511f7e370b6fa016c66790285d 317 Gene3D G3DSA:3.40.50.620 9 156 2.5E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS03630 863f87511f7e370b6fa016c66790285d 317 PRINTS PR01438 Universal stress protein signature 134 156 3.9E-6 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS03630 863f87511f7e370b6fa016c66790285d 317 PRINTS PR01438 Universal stress protein signature 116 128 3.9E-6 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS03630 863f87511f7e370b6fa016c66790285d 317 Pfam PF00582 Universal stress protein family 26 156 7.6E-18 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS03630 863f87511f7e370b6fa016c66790285d 317 Pfam PF00582 Universal stress protein family 179 315 1.0E-18 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 Gene3D G3DSA:3.40.50.740 330 618 3.0E-49 T 28-03-2018 SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 Gene3D G3DSA:3.40.50.740 121 329 5.4E-41 T 28-03-2018 SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 Pfam PF01568 Molydopterin dinucleotide binding domain 642 749 6.7E-10 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 755 4.2E-293 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 Gene3D G3DSA:2.40.40.20 631 759 3.4E-24 T 28-03-2018 SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 SUPERFAMILY SSF53706 58 631 6.54E-147 T 28-03-2018 SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 SUPERFAMILY SSF50692 631 756 4.29E-18 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 Pfam PF00384 Molybdopterin oxidoreductase 120 490 1.6E-28 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS10520 1664970ce193c39c8cfde3529094966b 759 PIRSF PIRSF000144 5 759 0.0 T 28-03-2018 SMD44_RS10655 e5ddf5ddfbd6c489f635a9a6af98d008 497 Gene3D G3DSA:1.20.1250.20 269 497 2.1E-24 T 28-03-2018 SMD44_RS10655 e5ddf5ddfbd6c489f635a9a6af98d008 497 Gene3D G3DSA:1.20.1250.20 19 216 2.1E-32 T 28-03-2018 SMD44_RS10655 e5ddf5ddfbd6c489f635a9a6af98d008 497 SUPERFAMILY SSF103473 18 212 6.54E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS10655 e5ddf5ddfbd6c489f635a9a6af98d008 497 SUPERFAMILY SSF103473 266 493 6.54E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS10655 e5ddf5ddfbd6c489f635a9a6af98d008 497 Pfam PF07690 Major Facilitator Superfamily 30 432 1.0E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS37120 57d1a9c35d69b2c458d506d986b7f1b7 317 Gene3D G3DSA:3.90.1200.10 92 287 1.1E-17 T 28-03-2018 SMD44_RS37120 57d1a9c35d69b2c458d506d986b7f1b7 317 Pfam PF01636 Phosphotransferase enzyme family 20 260 1.5E-21 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS37120 57d1a9c35d69b2c458d506d986b7f1b7 317 SUPERFAMILY SSF56112 11 276 6.98E-28 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS37120 57d1a9c35d69b2c458d506d986b7f1b7 317 Gene3D G3DSA:3.30.200.20 4 91 2.2E-9 T 28-03-2018 SMD44_RS14710 f9b5ff711517fc81cb3e0cf47d59e31c 500 Pfam PF00171 Aldehyde dehydrogenase family 16 478 8.5E-135 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS14710 f9b5ff711517fc81cb3e0cf47d59e31c 500 Gene3D G3DSA:3.40.605.10 1 263 3.3E-86 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS14710 f9b5ff711517fc81cb3e0cf47d59e31c 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS14710 f9b5ff711517fc81cb3e0cf47d59e31c 500 SUPERFAMILY SSF53720 2 484 3.14E-145 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS14710 f9b5ff711517fc81cb3e0cf47d59e31c 500 Gene3D G3DSA:3.40.309.10 264 461 8.0E-59 T 28-03-2018 SMD44_RS14710 f9b5ff711517fc81cb3e0cf47d59e31c 500 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 482 8.1E-258 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 SMD44_RS02765 66b5d140df5efa9509c6ddb2e749aa66 177 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 38 170 5.9E-37 T 28-03-2018 IPR005247 YbhB/YbcL SMD44_RS02765 66b5d140df5efa9509c6ddb2e749aa66 177 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 172 4.2E-37 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS02765 66b5d140df5efa9509c6ddb2e749aa66 177 SUPERFAMILY SSF49777 16 172 1.57E-49 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS02765 66b5d140df5efa9509c6ddb2e749aa66 177 Gene3D G3DSA:3.90.280.10 1 175 1.6E-53 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 PRINTS PR00046 Major sigma-70 factor signature 90 103 2.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 PRINTS PR00046 Major sigma-70 factor signature 240 252 2.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 PRINTS PR00046 Major sigma-70 factor signature 257 272 2.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 SUPERFAMILY SSF88946 18 135 9.16E-34 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 SUPERFAMILY SSF88659 206 287 9.16E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 60 286 4.0E-88 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 Pfam PF04542 Sigma-70 region 2 66 135 3.2E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 63 285 1.9E-34 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 Pfam PF04539 Sigma-70 region 3 146 198 2.2E-11 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 Pfam PF04545 Sigma-70, region 4 237 285 2.5E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 Gene3D G3DSA:1.10.601.10 26 134 3.1E-29 T 28-03-2018 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 90 103 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 Gene3D G3DSA:1.10.10.10 135 188 5.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 SUPERFAMILY SSF88659 139 218 1.83E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS40560 7f7a90959e5477e1cb00aea3bd1f40f9 292 Gene3D G3DSA:1.10.10.10 226 284 2.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30925 2d264be3e96adaaa77cd995c0638a2bd 667 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 146 517 4.5E-81 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS30925 2d264be3e96adaaa77cd995c0638a2bd 667 PIRSF PIRSF002741 82 619 1.3E-86 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS30925 2d264be3e96adaaa77cd995c0638a2bd 667 Gene3D G3DSA:3.90.76.10 110 252 3.2E-31 T 28-03-2018 SMD44_RS30925 2d264be3e96adaaa77cd995c0638a2bd 667 Gene3D G3DSA:1.20.5.100 625 665 5.3E-4 T 28-03-2018 SMD44_RS30925 2d264be3e96adaaa77cd995c0638a2bd 667 Gene3D G3DSA:3.40.190.10 253 376 2.4E-28 T 28-03-2018 SMD44_RS30925 2d264be3e96adaaa77cd995c0638a2bd 667 SUPERFAMILY SSF53850 99 617 4.16E-113 T 28-03-2018 SMD44_RS30925 2d264be3e96adaaa77cd995c0638a2bd 667 Gene3D G3DSA:3.10.105.10 377 584 1.3E-46 T 28-03-2018 SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 SMART SM00382 595 793 1.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 Pfam PF01580 FtsK/SpoIIIE family 564 760 2.0E-55 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 Gene3D G3DSA:1.10.10.10 861 915 1.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 142 257 1.7E-5 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 SUPERFAMILY SSF52540 533 832 5.31E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 Gene3D G3DSA:3.40.50.300 467 853 3.2E-45 T 28-03-2018 SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 SMART SM00843 860 924 9.7E-30 T 28-03-2018 IPR018541 FtsK gamma domain SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 SUPERFAMILY SSF46785 861 926 3.13E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31125 a668d3656ae195dcacbb74f00e8fe6fe 938 Pfam PF09397 Ftsk gamma domain 864 921 6.1E-22 T 28-03-2018 IPR018541 FtsK gamma domain SMD44_RS32235 2fa712e86b4963c5c3160569b6b31b05 106 Gene3D G3DSA:1.10.10.10 4 91 5.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32235 2fa712e86b4963c5c3160569b6b31b05 106 SUPERFAMILY SSF46785 10 98 2.72E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32235 2fa712e86b4963c5c3160569b6b31b05 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 4.4E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS32235 2fa712e86b4963c5c3160569b6b31b05 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 4.4E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS32235 2fa712e86b4963c5c3160569b6b31b05 106 Pfam PF12840 Helix-turn-helix domain 17 76 6.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS42390 ec722e3a968848fae75cb9930570d7e1 231 SUPERFAMILY SSF53098 7 149 5.94E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS42390 ec722e3a968848fae75cb9930570d7e1 231 Pfam PF00075 RNase H 9 149 3.7E-29 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 SMD44_RS42390 ec722e3a968848fae75cb9930570d7e1 231 Hamap MF_00042 Ribonuclease H [rnhA]. 6 158 30.756 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 SMD44_RS42390 ec722e3a968848fae75cb9930570d7e1 231 Gene3D G3DSA:3.30.420.10 5 152 2.6E-39 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS18765 86a16ed677e9b654ec87369a609d5b99 316 Gene3D G3DSA:3.40.50.10490 26 257 3.3E-52 T 28-03-2018 SMD44_RS18765 86a16ed677e9b654ec87369a609d5b99 316 Pfam PF01380 SIS domain 144 223 5.3E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS18765 86a16ed677e9b654ec87369a609d5b99 316 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 200 217 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 SMD44_RS18765 86a16ed677e9b654ec87369a609d5b99 316 SUPERFAMILY SSF53697 21 262 1.01E-64 T 28-03-2018 SMD44_RS18765 86a16ed677e9b654ec87369a609d5b99 316 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 17 310 41.324 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 SMD44_RS18765 86a16ed677e9b654ec87369a609d5b99 316 Gene3D G3DSA:1.10.8.10 258 286 3.7E-8 T 28-03-2018 SMD44_RS18765 86a16ed677e9b654ec87369a609d5b99 316 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 21 311 2.9E-110 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 SMD44_RS39380 626582a7ffae6019e81fc38e2e501a63 216 SUPERFAMILY SSF52540 32 205 1.88E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS39380 626582a7ffae6019e81fc38e2e501a63 216 Pfam PF03029 Conserved hypothetical ATP binding protein 37 203 2.4E-25 T 28-03-2018 IPR004130 GPN-loop GTPase SMD44_RS39380 626582a7ffae6019e81fc38e2e501a63 216 Gene3D G3DSA:3.40.50.300 23 210 3.2E-16 T 28-03-2018 SMD44_RS34145 46667751cc50ffd41e5171503f9a818a 762 SUPERFAMILY SSF50494 4 185 4.33E-11 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS34145 46667751cc50ffd41e5171503f9a818a 762 Gene3D G3DSA:3.40.50.2300 575 672 9.0E-5 T 28-03-2018 SMD44_RS34145 46667751cc50ffd41e5171503f9a818a 762 Pfam PF13365 Trypsin-like peptidase domain 31 173 3.7E-6 T 28-03-2018 SMD44_RS34145 46667751cc50ffd41e5171503f9a818a 762 Gene3D G3DSA:2.40.10.10 6 109 8.7E-4 T 28-03-2018 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 9.0E-250 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 SUPERFAMILY SSF48592 6 133 9.16E-76 T 28-03-2018 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 SUPERFAMILY SSF48592 404 518 9.16E-76 T 28-03-2018 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 SUPERFAMILY SSF54849 137 202 6.18E-27 T 28-03-2018 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 Gene3D G3DSA:3.50.7.10 182 371 1.1E-95 T 28-03-2018 IPR027409 GroEL-like apical domain SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.61 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 SUPERFAMILY SSF52029 184 374 6.13E-83 T 28-03-2018 IPR027409 GroEL-like apical domain SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 4.1E-98 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 Gene3D G3DSA:1.10.560.10 2 181 5.3E-32 T 28-03-2018 IPR027413 GroEL-like equatorial domain SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 Gene3D G3DSA:1.10.560.10 372 513 1.8E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 PRINTS PR00298 60kDa chaperonin signature 348 373 3.8E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 PRINTS PR00298 60kDa chaperonin signature 26 52 3.8E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 PRINTS PR00298 60kDa chaperonin signature 82 109 3.8E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 PRINTS PR00298 60kDa chaperonin signature 266 289 3.8E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS18790 f1cf2fee37a4614149a3ad08def6173b 541 PRINTS PR00298 60kDa chaperonin signature 396 417 3.8E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 SUPERFAMILY SSF52518 488 716 6.48E-85 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 Gene3D G3DSA:3.40.50.970 482 721 4.3E-62 T 28-03-2018 SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 SUPERFAMILY SSF52518 65 477 4.87E-113 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 PIRSF PIRSF000156 5 897 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 SUPERFAMILY SSF52922 720 897 3.49E-48 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 146 299 3.1E-9 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 14 896 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 Gene3D G3DSA:3.40.50.920 722 897 2.8E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS11540 dca5d3e44faca984b28d0f34e6d7dcc2 897 Gene3D G3DSA:3.40.50.970 64 481 6.6E-71 T 28-03-2018 SMD44_RS29640 77f6bd83df74d73879356ce8c4297965 183 SMART SM00641 2 101 2.4E-26 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup SMD44_RS29640 77f6bd83df74d73879356ce8c4297965 183 SUPERFAMILY SSF51445 3 169 1.97E-34 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS29640 77f6bd83df74d73879356ce8c4297965 183 Pfam PF01183 Glycosyl hydrolases family 25 5 163 5.5E-40 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 SMD44_RS29640 77f6bd83df74d73879356ce8c4297965 183 Gene3D G3DSA:3.20.20.80 1 177 9.8E-40 T 28-03-2018 SMD44_RS23705 464bfc6828abfbbc900c917c4cb47453 201 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMD44_RS23705 464bfc6828abfbbc900c917c4cb47453 201 SUPERFAMILY SSF55620 11 198 2.82E-77 T 28-03-2018 SMD44_RS23705 464bfc6828abfbbc900c917c4cb47453 201 Pfam PF01227 GTP cyclohydrolase I 22 198 2.5E-77 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMD44_RS23705 464bfc6828abfbbc900c917c4cb47453 201 Gene3D G3DSA:1.10.286.10 19 67 2.5E-23 T 28-03-2018 SMD44_RS23705 464bfc6828abfbbc900c917c4cb47453 201 Gene3D G3DSA:3.30.1130.10 68 201 7.4E-59 T 28-03-2018 SMD44_RS23705 464bfc6828abfbbc900c917c4cb47453 201 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMD44_RS23705 464bfc6828abfbbc900c917c4cb47453 201 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 17 199 41.923 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMD44_RS23705 464bfc6828abfbbc900c917c4cb47453 201 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 22 198 1.2E-71 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMD44_RS07580 5b6f03d3cf9cecb9ff27592a817a756d 184 Gene3D G3DSA:3.40.30.10 10 178 5.0E-33 T 28-03-2018 SMD44_RS07580 5b6f03d3cf9cecb9ff27592a817a756d 184 Pfam PF13462 Thioredoxin 21 175 1.5E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS07580 5b6f03d3cf9cecb9ff27592a817a756d 184 SUPERFAMILY SSF52833 20 175 6.87E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS27650 0a0337e0633eb8f144e44c3d9b4907ea 401 Gene3D G3DSA:3.40.50.1820 28 397 3.5E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27650 0a0337e0633eb8f144e44c3d9b4907ea 401 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 113 171 1.9E-6 T 28-03-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 SMD44_RS27650 0a0337e0633eb8f144e44c3d9b4907ea 401 SUPERFAMILY SSF53474 211 335 8.96E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27650 0a0337e0633eb8f144e44c3d9b4907ea 401 SUPERFAMILY SSF53474 362 385 8.96E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27650 0a0337e0633eb8f144e44c3d9b4907ea 401 SUPERFAMILY SSF53474 116 175 8.96E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS17855 d8f888cdbfc197decca4dd256334b3e6 491 Pfam PF00171 Aldehyde dehydrogenase family 12 487 2.6E-154 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS17855 d8f888cdbfc197decca4dd256334b3e6 491 Gene3D G3DSA:3.40.605.10 2 272 5.5E-81 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS17855 d8f888cdbfc197decca4dd256334b3e6 491 Gene3D G3DSA:3.40.309.10 273 473 4.7E-70 T 28-03-2018 SMD44_RS17855 d8f888cdbfc197decca4dd256334b3e6 491 SUPERFAMILY SSF53720 5 489 1.96E-147 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS40840 fa42b5ec03ddf0e60d4b6c5f2c9aed02 68 Gene3D G3DSA:3.40.190.10 1 68 1.4E-6 T 28-03-2018 SMD44_RS05340 7c10990d3561913c6bb94d0884209349 259 PIRSF PIRSF006157 4 259 3.2E-84 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 SMD44_RS05340 7c10990d3561913c6bb94d0884209349 259 SUPERFAMILY SSF53213 7 259 5.36E-84 T 28-03-2018 SMD44_RS05340 7c10990d3561913c6bb94d0884209349 259 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 10 236 7.9E-42 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 SMD44_RS05340 7c10990d3561913c6bb94d0884209349 259 Gene3D G3DSA:3.40.830.10 1 259 1.5E-79 T 28-03-2018 SMD44_RS05975 20d147c534d131eae46caf96b02add29 269 Gene3D G3DSA:3.40.50.720 1 151 2.5E-39 T 28-03-2018 SMD44_RS05975 20d147c534d131eae46caf96b02add29 269 Pfam PF00106 short chain dehydrogenase 10 202 1.4E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05975 20d147c534d131eae46caf96b02add29 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05975 20d147c534d131eae46caf96b02add29 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05975 20d147c534d131eae46caf96b02add29 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05975 20d147c534d131eae46caf96b02add29 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05975 20d147c534d131eae46caf96b02add29 269 SUPERFAMILY SSF51735 5 237 7.37E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS05975 20d147c534d131eae46caf96b02add29 269 Gene3D G3DSA:3.40.50.720 152 244 2.3E-7 T 28-03-2018 SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 2.9E-29 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 SUPERFAMILY SSF47979 65 137 6.15E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 Gene3D G3DSA:1.10.10.10 1 73 3.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 SUPERFAMILY SSF50037 130 229 3.66E-23 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 Pfam PF04023 FeoA domain 162 228 2.3E-6 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 3.7E-19 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 SUPERFAMILY SSF46785 3 62 1.24E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 Gene3D G3DSA:2.30.30.90 130 229 3.8E-22 T 28-03-2018 SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 Gene3D G3DSA:1.10.60.10 75 129 5.2E-24 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 SMART SM00899 153 229 2.1E-7 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SMD44_RS18235 31056b5f08d442ea5bf5d4e2eae3306f 230 SMART SM00529 26 125 6.0E-47 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 PIRSF PIRSF000098 3 429 2.4E-156 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 SUPERFAMILY SSF51735 4 159 7.18E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 SUPERFAMILY SSF55347 138 305 1.83E-52 T 28-03-2018 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 SUPERFAMILY SSF55021 349 421 6.87E-15 T 28-03-2018 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 Gene3D G3DSA:3.40.50.720 1 149 1.1E-24 T 28-03-2018 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 Gene3D G3DSA:3.30.70.260 347 425 1.7E-22 T 28-03-2018 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 Gene3D G3DSA:3.30.360.10 150 302 1.7E-57 T 28-03-2018 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 130 3.7E-21 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 Pfam PF01842 ACT domain 353 414 1.8E-13 T 28-03-2018 IPR002912 ACT domain SMD44_RS28800 2a1ed9866d36691a14d9430c71411b2c 429 Pfam PF00742 Homoserine dehydrogenase 138 318 4.0E-66 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMD44_RS26470 6c3a5658bdcd18132086ad6cc8f9dff4 421 Gene3D G3DSA:3.40.710.10 42 387 1.6E-39 T 28-03-2018 SMD44_RS26470 6c3a5658bdcd18132086ad6cc8f9dff4 421 SUPERFAMILY SSF56601 75 335 2.08E-44 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS26470 6c3a5658bdcd18132086ad6cc8f9dff4 421 SUPERFAMILY SSF56601 6 32 2.08E-44 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS26470 6c3a5658bdcd18132086ad6cc8f9dff4 421 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 73 315 9.1E-32 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD44_RS16120 100b2e26aff5283e16607c0cded960d8 709 Pfam PF00535 Glycosyl transferase family 2 5 103 2.8E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS16120 100b2e26aff5283e16607c0cded960d8 709 Gene3D G3DSA:3.90.550.10 1 294 2.9E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16120 100b2e26aff5283e16607c0cded960d8 709 SUPERFAMILY SSF53448 2 216 1.69E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16120 100b2e26aff5283e16607c0cded960d8 709 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 335 699 6.5E-119 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 SMD44_RS16120 100b2e26aff5283e16607c0cded960d8 709 SUPERFAMILY SSF53756 471 698 1.19E-9 T 28-03-2018 SMD44_RS07900 9eaed8a3dbb075d98a419f67734bde2b 383 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 68 377 1.1E-89 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMD44_RS07900 9eaed8a3dbb075d98a419f67734bde2b 383 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 379 45.741 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 SMD44_RS07900 9eaed8a3dbb075d98a419f67734bde2b 383 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 7.7E-15 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMD44_RS07900 9eaed8a3dbb075d98a419f67734bde2b 383 SUPERFAMILY SSF55681 109 380 8.42E-72 T 28-03-2018 SMD44_RS07900 9eaed8a3dbb075d98a419f67734bde2b 383 SUPERFAMILY SSF46589 29 115 2.46E-13 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 SMD44_RS07900 9eaed8a3dbb075d98a419f67734bde2b 383 Gene3D G3DSA:3.30.930.10 24 382 2.7E-77 T 28-03-2018 SMD44_RS07900 9eaed8a3dbb075d98a419f67734bde2b 383 Pfam PF01409 tRNA synthetases class II core domain (F) 109 378 7.6E-101 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 SMD44_RS29945 22b3382b8b42ba0ed5482a37e664cc47 207 SUPERFAMILY SSF52499 19 201 3.01E-41 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS29945 22b3382b8b42ba0ed5482a37e664cc47 207 Pfam PF00857 Isochorismatase family 27 197 1.2E-32 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS29945 22b3382b8b42ba0ed5482a37e664cc47 207 Gene3D G3DSA:3.40.50.850 24 206 4.2E-36 T 28-03-2018 SMD44_RS11115 3305cd056a76ba9e38fb4e77b00eddc4 694 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 5.7E-59 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal SMD44_RS11115 3305cd056a76ba9e38fb4e77b00eddc4 694 Pfam PF12698 ABC-2 family transporter protein 489 674 3.1E-16 T 28-03-2018 SMD44_RS11115 3305cd056a76ba9e38fb4e77b00eddc4 694 Gene3D G3DSA:1.10.287.950 229 321 0.002 T 28-03-2018 SMD44_RS11115 3305cd056a76ba9e38fb4e77b00eddc4 694 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 226 250 2.3E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat SMD44_RS11115 3305cd056a76ba9e38fb4e77b00eddc4 694 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 407 434 9.1E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat SMD44_RS11115 3305cd056a76ba9e38fb4e77b00eddc4 694 Gene3D G3DSA:3.40.1710.10 47 213 7.2E-25 T 28-03-2018 SMD44_RS11115 3305cd056a76ba9e38fb4e77b00eddc4 694 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 476 681 7.4E-71 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal SMD44_RS11115 3305cd056a76ba9e38fb4e77b00eddc4 694 Gene3D G3DSA:1.20.120.570 322 469 4.7E-11 T 28-03-2018 SMD44_RS12510 77fe9f16cd4e70ed67d18b9ffd8a65e8 349 Pfam PF01471 Putative peptidoglycan binding domain 284 342 1.0E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS12510 77fe9f16cd4e70ed67d18b9ffd8a65e8 349 SUPERFAMILY SSF47090 273 342 2.51E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS12510 77fe9f16cd4e70ed67d18b9ffd8a65e8 349 Gene3D G3DSA:1.10.101.10 270 348 1.8E-15 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS05690 97cd7d7e1b16450247f9b24336cf2c93 451 Gene3D G3DSA:3.40.50.300 120 377 4.8E-12 T 28-03-2018 SMD44_RS05690 97cd7d7e1b16450247f9b24336cf2c93 451 Pfam PF01580 FtsK/SpoIIIE family 141 333 2.8E-26 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS05690 97cd7d7e1b16450247f9b24336cf2c93 451 SUPERFAMILY SSF52540 154 395 5.84E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37075 9659396cd6a7a3ba6339703a45863486 467 SUPERFAMILY SSF52777 224 449 2.33E-6 T 28-03-2018 SMD44_RS37075 9659396cd6a7a3ba6339703a45863486 467 Pfam PF06974 Protein of unknown function (DUF1298) 298 441 7.9E-20 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 SMD44_RS37075 9659396cd6a7a3ba6339703a45863486 467 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 9 446 3.7E-114 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 SMD44_RS37075 9659396cd6a7a3ba6339703a45863486 467 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 9 255 1.6E-50 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 SMD44_RS37075 9659396cd6a7a3ba6339703a45863486 467 SUPERFAMILY SSF52777 63 149 9.12E-6 T 28-03-2018 SMD44_RS02995 3cc844dfc44ad9208b26b5f5a5378b0c 219 SMART SM00849 34 198 8.4E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS02995 3cc844dfc44ad9208b26b5f5a5378b0c 219 SUPERFAMILY SSF56281 20 211 1.9E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS02995 3cc844dfc44ad9208b26b5f5a5378b0c 219 Gene3D G3DSA:3.60.15.10 26 218 4.1E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS02995 3cc844dfc44ad9208b26b5f5a5378b0c 219 Pfam PF00753 Metallo-beta-lactamase superfamily 34 198 9.6E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 SUPERFAMILY SSF50104 249 303 5.31E-15 T 28-03-2018 IPR008991 Translation protein SH3-like domain SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 117 303 7.3E-54 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 SUPERFAMILY SSF82679 116 222 3.14E-34 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 SMART SM00738 114 222 1.4E-43 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 Pfam PF02357 Transcription termination factor nusG 116 218 2.1E-22 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 Gene3D G3DSA:3.30.70.940 115 226 7.2E-36 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 PRINTS PR00338 Transcription termination factor NUSG signature 169 181 4.8E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 PRINTS PR00338 Transcription termination factor NUSG signature 262 277 4.8E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 PRINTS PR00338 Transcription termination factor NUSG signature 280 296 4.8E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 114 304 22.428 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 SMART SM00739 250 277 3.5E-4 T 28-03-2018 IPR005824 KOW SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 Gene3D G3DSA:2.30.30.30 245 304 6.1E-18 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SMD44_RS25415 fdcf3fd2a6b73abe728f2e3e6611599b 304 ProSitePatterns PS01014 Transcription termination factor nusG signature. 287 296 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 SMART SM00344 1 106 3.5E-30 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 SUPERFAMILY SSF54909 64 145 4.16E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.9E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.9E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.9E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 Gene3D G3DSA:3.30.70.920 54 146 2.4E-17 T 28-03-2018 SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 Gene3D G3DSA:1.10.10.10 1 52 4.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 3.1E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 Pfam PF01037 Lrp/AsnC ligand binding domain 67 136 2.2E-16 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS01655 badb4b1dffaf12616af947643db1f7cb 152 SUPERFAMILY SSF46785 1 60 6.94E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03960 e86fab5a5e5035cb6cfe3abb6c00ddfb 434 Gene3D G3DSA:2.60.60.30 245 408 2.9E-30 T 28-03-2018 SMD44_RS03960 e86fab5a5e5035cb6cfe3abb6c00ddfb 434 Gene3D G3DSA:2.60.60.30 13 168 1.8E-50 T 28-03-2018 SMD44_RS03960 e86fab5a5e5035cb6cfe3abb6c00ddfb 434 PIRSF PIRSF037118 1 434 2.8E-169 T 28-03-2018 IPR017115 Tellurite resistance, TerA SMD44_RS03960 e86fab5a5e5035cb6cfe3abb6c00ddfb 434 Pfam PF02342 TerD domain 2 169 1.2E-49 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS32020 c714f6b7ac3d37f52f55ad469a67e39b 384 Pfam PF07690 Major Facilitator Superfamily 3 317 4.9E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS32020 c714f6b7ac3d37f52f55ad469a67e39b 384 Gene3D G3DSA:1.20.1250.20 181 380 4.9E-14 T 28-03-2018 SMD44_RS32020 c714f6b7ac3d37f52f55ad469a67e39b 384 SUPERFAMILY SSF103473 2 369 2.22E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS32020 c714f6b7ac3d37f52f55ad469a67e39b 384 Gene3D G3DSA:1.20.1250.20 1 175 8.0E-24 T 28-03-2018 SMD44_RS01295 562b06755143da599ab4c0c08b05c355 168 SMART SM00347 31 135 8.5E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS01295 562b06755143da599ab4c0c08b05c355 168 Pfam PF01047 MarR family 61 100 5.5E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS01295 562b06755143da599ab4c0c08b05c355 168 SUPERFAMILY SSF46785 11 150 5.71E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01295 562b06755143da599ab4c0c08b05c355 168 Gene3D G3DSA:1.10.10.10 2 145 3.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 Gene3D G3DSA:3.30.450.20 9 152 2.4E-18 T 28-03-2018 SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 SUPERFAMILY SSF55785 145 270 1.22E-17 T 28-03-2018 IPR000014 PAS domain SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 Gene3D G3DSA:3.30.450.20 153 311 3.8E-22 T 28-03-2018 SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 158 269 1.2E-7 T 28-03-2018 IPR000014 PAS domain SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 109 7.8E-8 T 28-03-2018 IPR000014 PAS domain SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 Gene3D G3DSA:3.30.565.10 366 557 5.1E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 Gene3D G3DSA:3.40.50.2300 1494 1628 1.3E-11 T 28-03-2018 SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 SUPERFAMILY SSF55785 10 110 3.14E-12 T 28-03-2018 IPR000014 PAS domain SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 SMART SM00091 10 76 2.4E-6 T 28-03-2018 IPR000014 PAS domain SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 SMART SM00091 155 223 4.0E-5 T 28-03-2018 IPR000014 PAS domain SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 Pfam PF00989 PAS fold 11 107 5.6E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 Pfam PF00989 PAS fold 159 270 1.3E-12 T 28-03-2018 IPR013767 PAS fold GO:0006355 SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 Pfam PF00072 Response regulator receiver domain 1509 1603 7.8E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS20395 df9006dd4d266a2bea26b2afdc7c8e6d 1630 SUPERFAMILY SSF52172 1504 1601 1.14E-12 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS19650 d8441b41efe4d261185889abaedee9d4 253 Pfam PF01061 ABC-2 type transporter 13 217 1.1E-24 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS19650 d8441b41efe4d261185889abaedee9d4 253 PIRSF PIRSF006648 1 253 1.2E-64 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 SMART SM00448 3 116 3.8E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 Pfam PF00072 Response regulator receiver domain 5 117 1.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 Gene3D G3DSA:3.40.50.2300 2 127 6.6E-38 T 28-03-2018 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 Gene3D G3DSA:1.10.10.10 128 221 3.5E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 1.2E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 1.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 1.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 1.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 SUPERFAMILY SSF46894 148 217 4.42E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 SMART SM00421 154 211 1.2E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23800 e07fac5958447087c09974dacd637e97 224 SUPERFAMILY SSF52172 1 135 4.13E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 Gene3D G3DSA:3.40.50.620 1 187 4.3E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 196 278 8.8E-36 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 SUPERFAMILY SSF52402 3 183 3.14E-35 T 28-03-2018 SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 259 285 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 SMART SM00893 4 183 5.5E-23 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 PIRSF PIRSF000089 1 320 2.0E-98 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 SUPERFAMILY SSF52467 194 314 2.77E-47 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 Pfam PF01012 Electron transfer flavoprotein domain 4 172 1.7E-27 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMD44_RS04845 7c9f9ded65b54ebd6f82e3bea5cee30d 320 Gene3D G3DSA:3.40.50.1220 191 320 5.7E-59 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS36400 d6c51c46443eee31882c864d8948fa8c 479 Gene3D G3DSA:3.30.420.40 231 477 1.1E-49 T 28-03-2018 SMD44_RS36400 d6c51c46443eee31882c864d8948fa8c 479 Gene3D G3DSA:3.30.420.40 2 230 6.5E-59 T 28-03-2018 SMD44_RS36400 d6c51c46443eee31882c864d8948fa8c 479 SUPERFAMILY SSF53067 5 235 3.67E-58 T 28-03-2018 SMD44_RS36400 d6c51c46443eee31882c864d8948fa8c 479 PIRSF PIRSF000538 3 479 8.1E-106 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD44_RS36400 d6c51c46443eee31882c864d8948fa8c 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 232 1.5E-44 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD44_RS36400 d6c51c46443eee31882c864d8948fa8c 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 242 424 1.8E-41 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD44_RS36400 d6c51c46443eee31882c864d8948fa8c 479 SUPERFAMILY SSF53067 236 469 1.08E-53 T 28-03-2018 SMD44_RS01615 e0315c566f0e47e4a6c379e582486bc5 141 SUPERFAMILY SSF55331 1 79 8.11E-7 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily SMD44_RS01615 e0315c566f0e47e4a6c379e582486bc5 141 Gene3D G3DSA:3.30.429.10 1 141 5.3E-41 T 28-03-2018 SMD44_RS01615 e0315c566f0e47e4a6c379e582486bc5 141 Pfam PF14832 Putative oxalocrotonate tautomerase enzyme 1 136 9.9E-48 T 28-03-2018 IPR028116 Putative oxalocrotonate tautomerase SMD44_RS18650 68921c5e50c0bf06e1e56e2a68453c82 981 Pfam PF13625 Helicase conserved C-terminal domain 689 811 4.8E-43 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 SMD44_RS32290 a662cf3d71ca1a15d7a4ebd229b59a22 399 SUPERFAMILY SSF46785 12 71 1.64E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32290 a662cf3d71ca1a15d7a4ebd229b59a22 399 Gene3D G3DSA:3.30.420.40 201 390 2.5E-58 T 28-03-2018 SMD44_RS32290 a662cf3d71ca1a15d7a4ebd229b59a22 399 Gene3D G3DSA:1.10.10.10 8 71 1.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32290 a662cf3d71ca1a15d7a4ebd229b59a22 399 Pfam PF12802 MarR family 17 68 1.6E-8 T 28-03-2018 SMD44_RS32290 a662cf3d71ca1a15d7a4ebd229b59a22 399 SUPERFAMILY SSF53067 79 383 9.73E-61 T 28-03-2018 SMD44_RS32290 a662cf3d71ca1a15d7a4ebd229b59a22 399 Gene3D G3DSA:3.30.420.40 72 200 8.7E-34 T 28-03-2018 SMD44_RS32290 a662cf3d71ca1a15d7a4ebd229b59a22 399 Pfam PF00480 ROK family 82 378 5.5E-61 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS32290 a662cf3d71ca1a15d7a4ebd229b59a22 399 ProSitePatterns PS01125 ROK family signature. 215 242 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS38315 2187b9204eef4b17e5dc3bdac7db7f69 278 SUPERFAMILY SSF52096 16 277 1.42E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS38315 2187b9204eef4b17e5dc3bdac7db7f69 278 Gene3D G3DSA:1.10.12.10 236 278 6.9E-8 T 28-03-2018 IPR014748 Crontonase, C-terminal SMD44_RS38315 2187b9204eef4b17e5dc3bdac7db7f69 278 Gene3D G3DSA:3.90.226.10 16 235 6.4E-54 T 28-03-2018 SMD44_RS38315 2187b9204eef4b17e5dc3bdac7db7f69 278 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 277 8.2E-42 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS18505 343cb39e8288556942d3bf86bebde760 330 Pfam PF00248 Aldo/keto reductase family 16 317 8.9E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS18505 343cb39e8288556942d3bf86bebde760 330 Gene3D G3DSA:3.20.20.100 3 319 4.2E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS18505 343cb39e8288556942d3bf86bebde760 330 SUPERFAMILY SSF51430 1 320 2.49E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS35845 e114a476fa4dac44db8a4ee9adddd2ad 302 Gene3D G3DSA:3.30.870.10 74 226 1.3E-5 T 28-03-2018 SMD44_RS35845 e114a476fa4dac44db8a4ee9adddd2ad 302 Gene3D G3DSA:1.10.10.10 227 286 3.5E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35845 e114a476fa4dac44db8a4ee9adddd2ad 302 SUPERFAMILY SSF46894 229 283 1.8E-5 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS35845 e114a476fa4dac44db8a4ee9adddd2ad 302 Pfam PF00196 Bacterial regulatory proteins, luxR family 229 278 5.4E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS35845 e114a476fa4dac44db8a4ee9adddd2ad 302 SUPERFAMILY SSF56024 73 217 7.22E-8 T 28-03-2018 SMD44_RS37140 c44bd826dd2a7580065dd207305acdea 312 Gene3D G3DSA:1.10.3720.10 33 299 4.3E-40 T 28-03-2018 SMD44_RS37140 c44bd826dd2a7580065dd207305acdea 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 305 1.2E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS37140 c44bd826dd2a7580065dd207305acdea 312 SUPERFAMILY SSF161098 43 312 1.57E-66 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS19825 97002a84ddd1273ada66173cf46b7450 350 Gene3D G3DSA:3.40.47.10 1 172 1.7E-8 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19825 97002a84ddd1273ada66173cf46b7450 350 SUPERFAMILY SSF53901 5 346 6.52E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS19825 97002a84ddd1273ada66173cf46b7450 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 283 346 1.6E-6 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD44_RS19825 97002a84ddd1273ada66173cf46b7450 350 Gene3D G3DSA:3.40.47.10 173 346 9.7E-17 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS42175 05923d236d11078b25cb90357ae40243 197 Pfam PF00501 AMP-binding enzyme 5 83 2.5E-19 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS42175 05923d236d11078b25cb90357ae40243 197 Pfam PF00501 AMP-binding enzyme 121 178 3.4E-12 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS42175 05923d236d11078b25cb90357ae40243 197 Gene3D G3DSA:3.40.50.980 96 138 7.6E-10 T 28-03-2018 SMD44_RS42175 05923d236d11078b25cb90357ae40243 197 SUPERFAMILY SSF56801 2 179 3.4E-44 T 28-03-2018 SMD44_RS42175 05923d236d11078b25cb90357ae40243 197 Gene3D G3DSA:3.40.50.980 1 95 1.5E-27 T 28-03-2018 SMD44_RS42175 05923d236d11078b25cb90357ae40243 197 Gene3D G3DSA:3.40.50.980 139 189 6.0E-15 T 28-03-2018 SMD44_RS42175 05923d236d11078b25cb90357ae40243 197 ProSitePatterns PS00455 Putative AMP-binding domain signature. 133 144 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS34620 5b2804b1fd2a18b93224635f2ddb4e0c 415 Gene3D G3DSA:2.115.10.20 15 406 2.8E-10 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMD44_RS34620 5b2804b1fd2a18b93224635f2ddb4e0c 415 Pfam PF13810 Domain of unknown function (DUF4185) 215 368 7.3E-10 T 28-03-2018 IPR025442 Domain of unknown function DUF4185 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 SUPERFAMILY SSF50621 301 436 1.51E-29 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 82 318 1.4E-32 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 Gene3D G3DSA:2.40.37.10 313 474 2.8E-33 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 SUPERFAMILY SSF51419 61 322 1.96E-52 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 259 276 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 309 328 5.7E-11 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 110 122 5.7E-11 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 90 108 5.7E-11 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 223 236 5.7E-11 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 414 427 5.7E-11 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 Gene3D G3DSA:3.20.20.10 63 312 6.3E-49 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS16635 ce842f2aafd6ede0272b75d57910bebe 475 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 320 414 1.6E-11 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD44_RS17530 9bd22cab1042f366bc9a69d69a4e6c01 158 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 15 94 1.4E-12 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SMD44_RS17530 9bd22cab1042f366bc9a69d69a4e6c01 158 SUPERFAMILY SSF53927 1 116 1.17E-25 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMD44_RS17530 9bd22cab1042f366bc9a69d69a4e6c01 158 Gene3D G3DSA:3.40.140.10 1 145 3.6E-21 T 28-03-2018 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Pfam PF13380 CoA binding domain 230 359 6.3E-16 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 SUPERFAMILY SSF56059 761 960 1.34E-22 T 28-03-2018 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 SUPERFAMILY SSF52210 518 651 3.79E-14 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Gene3D G3DSA:3.30.470.20 835 972 8.4E-34 T 28-03-2018 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 SUPERFAMILY SSF51735 223 353 4.6E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Pfam PF13549 ATP-grasp domain 759 968 3.9E-54 T 28-03-2018 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 SUPERFAMILY SSF52210 353 521 8.24E-32 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Pfam PF00583 Acetyltransferase (GNAT) family 71 183 2.3E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Gene3D G3DSA:3.40.50.720 225 349 6.4E-43 T 28-03-2018 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Gene3D G3DSA:3.40.630.30 32 224 3.5E-28 T 28-03-2018 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Gene3D G3DSA:3.40.50.261 519 546 0.0025 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Gene3D G3DSA:3.40.50.261 547 728 2.7E-30 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Gene3D G3DSA:3.30.1490.20 750 834 1.6E-6 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Gene3D G3DSA:3.40.50.261 350 518 5.9E-40 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 SUPERFAMILY SSF55729 40 191 5.32E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 377 513 7.9E-38 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SMD44_RS31650 b54a3cdbfcafaf1d4359d90902400f78 985 SMART SM00881 225 324 3.2E-26 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 SUPERFAMILY SSF54768 33 99 1.46E-21 T 28-03-2018 SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 SUPERFAMILY SSF54211 102 181 3.79E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 32 186 7.6E-68 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 Gene3D G3DSA:3.30.160.20 33 94 4.0E-25 T 28-03-2018 SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 Gene3D G3DSA:3.30.230.10 100 189 4.9E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 110 180 4.5E-28 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 36 98 5.3E-27 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 51 83 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site SMD44_RS25590 8dfe30d009aada8f033be1eec2cead11 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 186 34.376 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD44_RS12155 d8910601a4dd817996a5f9b5395d9330 307 Gene3D G3DSA:3.90.550.10 4 228 1.5E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS12155 d8910601a4dd817996a5f9b5395d9330 307 Pfam PF13641 Glycosyltransferase like family 2 5 208 2.9E-9 T 28-03-2018 SMD44_RS12155 d8910601a4dd817996a5f9b5395d9330 307 SUPERFAMILY SSF53448 10 223 7.59E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS31730 0d77a9887da6f2e935d7de6d60b44d01 148 Pfam PF11292 Protein of unknown function (DUF3093) 4 142 5.2E-44 T 28-03-2018 IPR021443 Protein of unknown function DUF3093 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 Gene3D G3DSA:2.60.40.1180 380 463 4.3E-13 T 28-03-2018 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 SUPERFAMILY SSF56988 473 612 4.97E-42 T 28-03-2018 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 Gene3D G3DSA:3.20.20.80 49 379 4.6E-98 T 28-03-2018 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 Pfam PF07691 PA14 domain 473 607 1.5E-28 T 28-03-2018 IPR011658 PA14 domain SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 Gene3D G3DSA:3.90.182.10 470 613 4.4E-39 T 28-03-2018 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 Pfam PF01120 Alpha-L-fucosidase 59 367 2.9E-87 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 SUPERFAMILY SSF51445 54 368 6.11E-89 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 SMART SM00758 471 608 2.7E-26 T 28-03-2018 IPR011658 PA14 domain SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 PRINTS PR00741 Glycosyl hydrolase family 29 signature 220 236 3.4E-19 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 PRINTS PR00741 Glycosyl hydrolase family 29 signature 137 153 3.4E-19 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 PRINTS PR00741 Glycosyl hydrolase family 29 signature 321 342 3.4E-19 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 PRINTS PR00741 Glycosyl hydrolase family 29 signature 354 376 3.4E-19 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMD44_RS33405 1d0518e0b50f5cedef8f3f60832141f1 613 SMART SM00812 54 415 1.4E-94 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMD44_RS20930 1ab5d79a9c80dc9a341d8355ccf138f5 403 Gene3D G3DSA:1.20.1250.20 3 192 6.7E-30 T 28-03-2018 SMD44_RS20930 1ab5d79a9c80dc9a341d8355ccf138f5 403 Gene3D G3DSA:1.20.1250.20 193 383 4.0E-17 T 28-03-2018 SMD44_RS20930 1ab5d79a9c80dc9a341d8355ccf138f5 403 SUPERFAMILY SSF103473 3 375 1.83E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20930 1ab5d79a9c80dc9a341d8355ccf138f5 403 Pfam PF07690 Major Facilitator Superfamily 8 328 6.2E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS31290 d48f0fe377e3007b8bc16bdd11b1096f 340 SUPERFAMILY SSF56112 28 184 9.28E-45 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS31290 d48f0fe377e3007b8bc16bdd11b1096f 340 SUPERFAMILY SSF56112 211 308 9.28E-45 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS31290 d48f0fe377e3007b8bc16bdd11b1096f 340 Pfam PF01636 Phosphotransferase enzyme family 45 303 2.2E-34 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS31290 d48f0fe377e3007b8bc16bdd11b1096f 340 Gene3D G3DSA:1.10.510.10 71 296 3.0E-23 T 28-03-2018 SMD44_RS42955 7644fc87a0ebd5b48d77231169b9c452 511 Pfam PF00561 alpha/beta hydrolase fold 94 451 5.1E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS42955 7644fc87a0ebd5b48d77231169b9c452 511 SUPERFAMILY SSF53474 334 458 1.82E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS42955 7644fc87a0ebd5b48d77231169b9c452 511 SUPERFAMILY SSF53474 183 237 1.82E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS42955 7644fc87a0ebd5b48d77231169b9c452 511 SUPERFAMILY SSF53474 86 141 1.82E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS42955 7644fc87a0ebd5b48d77231169b9c452 511 Gene3D G3DSA:3.40.50.1820 5 475 8.9E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS37680 0d4b49bc4dd5324155e46e8c39949d17 77 Gene3D G3DSA:3.30.465.10 22 77 3.2E-9 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS37680 0d4b49bc4dd5324155e46e8c39949d17 77 Pfam PF03471 Transporter associated domain 31 63 1.6E-6 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS37680 0d4b49bc4dd5324155e46e8c39949d17 77 SUPERFAMILY SSF56176 29 70 2.43E-7 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS08655 975d6b5d52c559b970baabd7beeb55e4 304 Pfam PF13602 Zinc-binding dehydrogenase 195 300 2.5E-15 T 28-03-2018 SMD44_RS08655 975d6b5d52c559b970baabd7beeb55e4 304 Gene3D G3DSA:3.90.180.10 180 303 6.8E-10 T 28-03-2018 SMD44_RS08655 975d6b5d52c559b970baabd7beeb55e4 304 Gene3D G3DSA:3.90.180.10 1 179 5.5E-51 T 28-03-2018 SMD44_RS08655 975d6b5d52c559b970baabd7beeb55e4 304 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS08655 975d6b5d52c559b970baabd7beeb55e4 304 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 8.2E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS08655 975d6b5d52c559b970baabd7beeb55e4 304 SUPERFAMILY SSF50129 1 145 1.98E-34 T 28-03-2018 IPR011032 GroES-like SMD44_RS08655 975d6b5d52c559b970baabd7beeb55e4 304 SMART SM00829 10 300 2.9E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS08655 975d6b5d52c559b970baabd7beeb55e4 304 SUPERFAMILY SSF51735 113 234 1.21E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS17415 69d546ef3d16ab329ed15f7737b0d6ac 326 SUPERFAMILY SSF46785 7 65 6.42E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17415 69d546ef3d16ab329ed15f7737b0d6ac 326 PIRSF PIRSF016838 266 324 33.0 T 28-03-2018 IPR028349 Protein PafC SMD44_RS17415 69d546ef3d16ab329ed15f7737b0d6ac 326 PIRSF PIRSF016838 1 223 7.4E-21 T 28-03-2018 IPR028349 Protein PafC SMD44_RS17415 69d546ef3d16ab329ed15f7737b0d6ac 326 Gene3D G3DSA:1.10.10.10 2 67 1.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17415 69d546ef3d16ab329ed15f7737b0d6ac 326 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD44_RS17415 69d546ef3d16ab329ed15f7737b0d6ac 326 Pfam PF13280 WYL domain 143 317 7.1E-22 T 28-03-2018 IPR026881 WYL domain SMD44_RS17415 69d546ef3d16ab329ed15f7737b0d6ac 326 Pfam PF08279 HTH domain 8 63 2.3E-17 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SMD44_RS12500 e827f6caa3792d63445ad6486dcb4dad 177 SUPERFAMILY SSF55729 24 162 1.1E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS12500 e827f6caa3792d63445ad6486dcb4dad 177 Gene3D G3DSA:3.40.630.30 16 171 2.5E-22 T 28-03-2018 SMD44_RS12500 e827f6caa3792d63445ad6486dcb4dad 177 Pfam PF00583 Acetyltransferase (GNAT) family 59 152 5.7E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS29335 0c90385562b21b16855a70cc451067c6 481 Gene3D G3DSA:2.60.120.200 42 321 2.1E-60 T 28-03-2018 SMD44_RS29335 0c90385562b21b16855a70cc451067c6 481 Pfam PF00722 Glycosyl hydrolases family 16 112 269 1.9E-9 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 SMD44_RS29335 0c90385562b21b16855a70cc451067c6 481 SUPERFAMILY SSF49899 40 317 1.25E-48 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS37205 8282316458a55ad0d68d28ad04ff524d 104 SUPERFAMILY SSF54909 1 103 1.93E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS37205 8282316458a55ad0d68d28ad04ff524d 104 Pfam PF05336 L-rhamnose mutarotase 2 91 5.7E-18 T 28-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 SMD44_RS12470 edfe1e862a7914982c6eacdd582f4dac 747 SUPERFAMILY SSF48317 479 665 2.68E-5 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS12470 edfe1e862a7914982c6eacdd582f4dac 747 Pfam PF14378 PAP2 superfamily 476 657 7.0E-50 T 28-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD44_RS12470 edfe1e862a7914982c6eacdd582f4dac 747 Pfam PF09594 Glycosyltransferase family 87 89 324 2.4E-35 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD44_RS25100 782e300aedc10cd340a31f97817297e4 417 SUPERFAMILY SSF56059 131 341 2.65E-20 T 28-03-2018 SMD44_RS25100 782e300aedc10cd340a31f97817297e4 417 Gene3D G3DSA:3.30.470.20 123 393 9.6E-29 T 28-03-2018 SMD44_RS34965 07c1d26ccff88a1618edfe1fd93f8697 1076 SUPERFAMILY SSF52540 283 449 2.29E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34965 07c1d26ccff88a1618edfe1fd93f8697 1076 Gene3D G3DSA:3.40.50.300 105 451 6.7E-6 T 28-03-2018 SMD44_RS34965 07c1d26ccff88a1618edfe1fd93f8697 1076 Pfam PF05729 NACHT domain 285 448 2.9E-25 T 28-03-2018 SMD44_RS34965 07c1d26ccff88a1618edfe1fd93f8697 1076 Gene3D G3DSA:3.80.10.10 922 1064 1.1E-9 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMD44_RS34965 07c1d26ccff88a1618edfe1fd93f8697 1076 Gene3D G3DSA:3.80.10.10 800 921 2.3E-10 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMD44_RS34965 07c1d26ccff88a1618edfe1fd93f8697 1076 SUPERFAMILY SSF52047 832 1054 2.04E-15 T 28-03-2018 SMD44_RS08255 9e91c82fb2593ef38c58b767f98f80d1 265 Pfam PF01048 Phosphorylase superfamily 23 246 3.1E-35 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS08255 9e91c82fb2593ef38c58b767f98f80d1 265 SUPERFAMILY SSF53167 10 249 1.17E-50 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS08255 9e91c82fb2593ef38c58b767f98f80d1 265 Gene3D G3DSA:3.40.50.1580 17 248 1.6E-36 T 28-03-2018 SMD44_RS35605 43821143e854decacdff8729b1a46c38 408 Pfam PF12706 Beta-lactamase superfamily domain 111 325 1.6E-51 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS35605 43821143e854decacdff8729b1a46c38 408 SUPERFAMILY SSF56281 94 171 9.17E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS35605 43821143e854decacdff8729b1a46c38 408 SUPERFAMILY SSF56281 198 363 9.17E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS35605 43821143e854decacdff8729b1a46c38 408 Gene3D G3DSA:3.60.15.10 58 367 4.0E-51 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS12650 5ae595fcaddcc44a3405f9c57798bfc7 73 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 48 1.2E-16 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD44_RS12650 5ae595fcaddcc44a3405f9c57798bfc7 73 Pfam PF09723 Zinc ribbon domain 1 40 2.1E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD44_RS12650 5ae595fcaddcc44a3405f9c57798bfc7 73 SMART SM00834 1 42 2.7E-13 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD44_RS31630 0f31be494bf86bea0ae0403093d76fc0 275 SUPERFAMILY SSF51261 78 268 2.09E-46 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS31630 0f31be494bf86bea0ae0403093d76fc0 275 Gene3D G3DSA:2.70.70.10 97 271 1.0E-47 T 28-03-2018 SMD44_RS31630 0f31be494bf86bea0ae0403093d76fc0 275 Pfam PF01551 Peptidase family M23 167 264 3.8E-32 T 28-03-2018 IPR016047 Peptidase M23 SMD44_RS03240 053a330ba407712e32cc4a9bea5e6a5d 483 Gene3D G3DSA:2.140.10.10 271 448 2.2E-16 T 28-03-2018 SMD44_RS03240 053a330ba407712e32cc4a9bea5e6a5d 483 SUPERFAMILY SSF50998 105 369 2.94E-21 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS03240 053a330ba407712e32cc4a9bea5e6a5d 483 Pfam PF05406 WGR domain 10 77 1.2E-17 T 28-03-2018 IPR008893 WGR domain SMD44_RS03240 053a330ba407712e32cc4a9bea5e6a5d 483 Gene3D G3DSA:2.140.10.10 67 270 2.5E-11 T 28-03-2018 SMD44_RS03240 053a330ba407712e32cc4a9bea5e6a5d 483 Pfam PF13360 PQQ-like domain 247 375 9.4E-12 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS03240 053a330ba407712e32cc4a9bea5e6a5d 483 SUPERFAMILY SSF142921 10 77 6.02E-10 T 28-03-2018 IPR008893 WGR domain SMD44_RS03240 053a330ba407712e32cc4a9bea5e6a5d 483 Gene3D G3DSA:2.20.140.10 11 66 1.1E-15 T 28-03-2018 IPR008893 WGR domain SMD44_RS03240 053a330ba407712e32cc4a9bea5e6a5d 483 SMART SM00773 8 81 6.4E-20 T 28-03-2018 IPR008893 WGR domain SMD44_RS03755 a726412320439788be22cd1bcc829622 480 Gene3D G3DSA:1.20.1250.20 3 197 6.7E-30 T 28-03-2018 SMD44_RS03755 a726412320439788be22cd1bcc829622 480 Pfam PF07690 Major Facilitator Superfamily 16 408 2.5E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS03755 a726412320439788be22cd1bcc829622 480 Gene3D G3DSA:1.20.1250.20 249 471 8.7E-24 T 28-03-2018 SMD44_RS03755 a726412320439788be22cd1bcc829622 480 SUPERFAMILY SSF103473 4 193 8.46E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03755 a726412320439788be22cd1bcc829622 480 SUPERFAMILY SSF103473 245 460 8.46E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS21295 20348c277520eb3e3dece54dd855d378 590 PRINTS PR01806 Virulence factor MviN signature 423 442 3.4E-19 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS21295 20348c277520eb3e3dece54dd855d378 590 PRINTS PR01806 Virulence factor MviN signature 476 493 3.4E-19 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS21295 20348c277520eb3e3dece54dd855d378 590 PRINTS PR01806 Virulence factor MviN signature 220 241 3.4E-19 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS21295 20348c277520eb3e3dece54dd855d378 590 PRINTS PR01806 Virulence factor MviN signature 326 352 3.4E-19 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS21295 20348c277520eb3e3dece54dd855d378 590 PRINTS PR01806 Virulence factor MviN signature 92 111 3.4E-19 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS21295 20348c277520eb3e3dece54dd855d378 590 PRINTS PR01806 Virulence factor MviN signature 196 220 3.4E-19 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS21295 20348c277520eb3e3dece54dd855d378 590 Pfam PF03023 MviN-like protein 87 530 1.2E-56 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD44_RS42870 7a819063c07ac4d00d46fd42d057f81e 351 Pfam PF00248 Aldo/keto reductase family 46 328 2.0E-20 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS42870 7a819063c07ac4d00d46fd42d057f81e 351 Gene3D G3DSA:3.20.20.100 9 348 3.2E-35 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS42870 7a819063c07ac4d00d46fd42d057f81e 351 SUPERFAMILY SSF51430 37 334 4.19E-30 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS17325 3969c9fc337dde11b5e62fdd56b9e367 421 Gene3D G3DSA:1.20.1250.20 11 215 8.9E-15 T 28-03-2018 SMD44_RS17325 3969c9fc337dde11b5e62fdd56b9e367 421 Gene3D G3DSA:1.20.1250.20 217 416 8.7E-16 T 28-03-2018 SMD44_RS17325 3969c9fc337dde11b5e62fdd56b9e367 421 SUPERFAMILY SSF103473 17 402 4.19E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17325 3969c9fc337dde11b5e62fdd56b9e367 421 Pfam PF07690 Major Facilitator Superfamily 35 304 2.2E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS18830 5ce4468ed189cb7eefc6c163a1e6fe7e 407 Gene3D G3DSA:3.40.190.10 5 167 1.3E-30 T 28-03-2018 SMD44_RS18830 5ce4468ed189cb7eefc6c163a1e6fe7e 407 Pfam PF13416 Bacterial extracellular solute-binding protein 42 339 4.7E-39 T 28-03-2018 SMD44_RS18830 5ce4468ed189cb7eefc6c163a1e6fe7e 407 Gene3D G3DSA:3.40.190.10 168 362 5.3E-10 T 28-03-2018 SMD44_RS18830 5ce4468ed189cb7eefc6c163a1e6fe7e 407 SUPERFAMILY SSF53850 33 399 1.24E-59 T 28-03-2018 SMD44_RS07560 19fc66620938e0aec9d1e8c0b5dc0697 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.6E-38 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD44_RS29775 97c3665bd9c68aea51499f331e66d9e4 380 SUPERFAMILY SSF52402 17 260 1.12E-45 T 28-03-2018 SMD44_RS29775 97c3665bd9c68aea51499f331e66d9e4 380 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 18 370 4.5E-86 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SMD44_RS29775 97c3665bd9c68aea51499f331e66d9e4 380 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 16 371 35.971 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SMD44_RS29775 97c3665bd9c68aea51499f331e66d9e4 380 Pfam PF03054 tRNA methyl transferase 17 370 8.6E-118 T 28-03-2018 SMD44_RS29775 97c3665bd9c68aea51499f331e66d9e4 380 Gene3D G3DSA:2.30.30.280 230 293 2.4E-17 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 SMD44_RS29775 97c3665bd9c68aea51499f331e66d9e4 380 Gene3D G3DSA:2.40.30.10 294 379 2.2E-21 T 28-03-2018 SMD44_RS29775 97c3665bd9c68aea51499f331e66d9e4 380 Gene3D G3DSA:3.40.50.620 9 228 2.5E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS06400 7421c4654ecc58ae56538fefd7dca78d 228 Pfam PF16859 Bacterial transcriptional repressor C-terminal 89 197 1.6E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS06400 7421c4654ecc58ae56538fefd7dca78d 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 2.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06400 7421c4654ecc58ae56538fefd7dca78d 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 2.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06400 7421c4654ecc58ae56538fefd7dca78d 228 SUPERFAMILY SSF46689 22 83 9.23E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS06400 7421c4654ecc58ae56538fefd7dca78d 228 Gene3D G3DSA:1.10.10.60 1 76 6.4E-16 T 28-03-2018 SMD44_RS06400 7421c4654ecc58ae56538fefd7dca78d 228 Gene3D G3DSA:1.10.357.10 77 211 2.8E-19 T 28-03-2018 SMD44_RS06400 7421c4654ecc58ae56538fefd7dca78d 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 1.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS06400 7421c4654ecc58ae56538fefd7dca78d 228 SUPERFAMILY SSF48498 89 207 1.85E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS31390 fbc7942fa5b29584263a2149974fc492 404 Gene3D G3DSA:2.40.10.10 161 292 2.5E-11 T 28-03-2018 SMD44_RS31390 fbc7942fa5b29584263a2149974fc492 404 SUPERFAMILY SSF50494 153 376 1.93E-18 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS31390 fbc7942fa5b29584263a2149974fc492 404 Gene3D G3DSA:2.40.10.10 293 401 6.8E-24 T 28-03-2018 SMD44_RS17765 b0018e3c2cb4a99abc1de70339706502 116 Pfam PF14279 HNH endonuclease 62 104 5.3E-9 T 28-03-2018 IPR029471 HNH endonuclease 5 SMD44_RS17765 b0018e3c2cb4a99abc1de70339706502 116 Gene3D G3DSA:3.40.1800.10 40 115 3.5E-16 T 28-03-2018 SMD44_RS17765 b0018e3c2cb4a99abc1de70339706502 116 SMART SM00507 49 102 3.3E-7 T 28-03-2018 IPR003615 HNH nuclease SMD44_RS18775 0ae6b7444603c58d11ab7285416c5648 392 Pfam PF04188 Mannosyltransferase (PIG-V) 147 211 6.1E-5 T 28-03-2018 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 Reactome: R-HSA-162710 SMD44_RS15695 8d73d8506f1c2c20fee0e63c38b8cd28 105 SUPERFAMILY SSF54736 26 101 4.71E-25 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD44_RS15695 8d73d8506f1c2c20fee0e63c38b8cd28 105 Gene3D G3DSA:3.30.1390.10 29 100 1.9E-26 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD44_RS15695 8d73d8506f1c2c20fee0e63c38b8cd28 105 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 29 98 1.5E-22 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 SMD44_RS15695 8d73d8506f1c2c20fee0e63c38b8cd28 105 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 13 104 17.527 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 ProSitePatterns PS00012 Phosphopantetheine attachment site. 587 602 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 Gene3D G3DSA:3.40.50.720 268 522 1.8E-49 T 28-03-2018 SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 Pfam PF08659 KR domain 273 450 5.0E-57 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 SMART SM00823 Phosphopantetheine attachment site 560 616 4.8E-17 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 Gene3D G3DSA:1.10.1200.10 530 624 2.7E-11 T 28-03-2018 SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 SUPERFAMILY SSF47336 552 613 1.14E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 Pfam PF00550 Phosphopantetheine attachment site 562 613 4.7E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 6 33 2.1E-4 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 SMART SM00829 1 263 7.6E-92 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 SUPERFAMILY SSF51735 271 522 4.28E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 SUPERFAMILY SSF50129 5 86 6.76E-20 T 28-03-2018 IPR011032 GroES-like SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 Pfam PF13602 Zinc-binding dehydrogenase 135 263 2.7E-20 T 28-03-2018 SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 SUPERFAMILY SSF51735 58 234 1.14E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 273 451 6.2E-53 T 28-03-2018 SMD44_RS36885 bec8a3aafd65a01aadaae9bc8c4f8167 1096 Gene3D G3DSA:3.90.180.10 1 265 2.0E-48 T 28-03-2018 SMD44_RS23270 360381986a4922dff5012e1cb3a43e9b 290 Pfam PF00482 Type II secretion system (T2SS), protein F 110 242 1.3E-8 T 28-03-2018 IPR018076 Type II secretion system F domain SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 335 2.8E-120 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 314 325 1.1E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 233 243 1.1E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 69 1.1E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 128 142 1.1E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 88 101 1.1E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 336 79.349 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 333 1.8E-50 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 Gene3D G3DSA:3.40.50.1370 1 151 1.3E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 152 1.9E-44 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 Gene3D G3DSA:3.40.50.1370 152 322 1.4E-49 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 1.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 271 280 1.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 1.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 300 323 1.1E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS32145 9a02b363410db4f55ed2b3405c1339df 336 SUPERFAMILY SSF53671 8 335 2.75E-91 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS01670 b2a5c27e1bb88fd7b05424ed7152dad6 410 Gene3D G3DSA:3.40.630.30 133 298 7.5E-51 T 28-03-2018 SMD44_RS01670 b2a5c27e1bb88fd7b05424ed7152dad6 410 Pfam PF13527 Acetyltransferase (GNAT) domain 2 129 2.4E-25 T 28-03-2018 SMD44_RS01670 b2a5c27e1bb88fd7b05424ed7152dad6 410 Hamap MF_01812 UPF0256 protein . 12 410 30.782 T 28-03-2018 IPR022902 N-acetyltransferase Eis SMD44_RS01670 b2a5c27e1bb88fd7b05424ed7152dad6 410 Gene3D G3DSA:3.40.630.30 1 132 6.8E-15 T 28-03-2018 SMD44_RS01670 b2a5c27e1bb88fd7b05424ed7152dad6 410 SUPERFAMILY SSF55718 306 410 2.43E-24 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS01670 b2a5c27e1bb88fd7b05424ed7152dad6 410 Gene3D G3DSA:3.30.1050.10 304 401 5.8E-28 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS01670 b2a5c27e1bb88fd7b05424ed7152dad6 410 SUPERFAMILY SSF55729 1 305 8.43E-59 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS01670 b2a5c27e1bb88fd7b05424ed7152dad6 410 Pfam PF13530 Sterol carrier protein domain 189 406 2.9E-48 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain SMD44_RS09060 847dfc94e06184bb5f9af49ad921a8df 140 Gene3D G3DSA:1.10.10.690 6 139 3.1E-38 T 28-03-2018 SMD44_RS09060 847dfc94e06184bb5f9af49ad921a8df 140 Pfam PF06078 Bacterial protein of unknown function (DUF937) 6 123 1.1E-11 T 28-03-2018 IPR009282 Protein of unknown function DUF937 SMD44_RS09060 847dfc94e06184bb5f9af49ad921a8df 140 SUPERFAMILY SSF140804 24 133 4.58E-26 T 28-03-2018 IPR027405 YidB-like SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 Gene3D G3DSA:3.40.50.2300 170 330 2.9E-32 T 28-03-2018 SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 SUPERFAMILY SSF53822 57 310 6.28E-32 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 49 1.8E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 Gene3D G3DSA:3.40.50.2300 57 169 4.5E-16 T 28-03-2018 SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 28-03-2018 SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 Gene3D G3DSA:1.10.260.40 3 56 2.8E-13 T 28-03-2018 SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 SMART SM00354 5 70 4.6E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 Pfam PF13377 Periplasmic binding protein-like domain 170 327 4.4E-28 T 28-03-2018 SMD44_RS32215 f31e09d95faa6fd52e5b2565bc4c50d6 342 SUPERFAMILY SSF47413 6 50 3.94E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS10545 ec1376fe33bb03fb4e610cb71774322b 312 Pfam PF00005 ABC transporter 29 188 7.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS10545 ec1376fe33bb03fb4e610cb71774322b 312 SMART SM00382 37 235 2.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS10545 ec1376fe33bb03fb4e610cb71774322b 312 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 2.4E-6 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal SMD44_RS10545 ec1376fe33bb03fb4e610cb71774322b 312 Gene3D G3DSA:3.40.50.300 9 298 3.1E-57 T 28-03-2018 SMD44_RS10545 ec1376fe33bb03fb4e610cb71774322b 312 SUPERFAMILY SSF52540 11 257 3.88E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS19780 2670a05f9f6273204fcfbf28e8a927f9 319 SUPERFAMILY SSF51735 4 307 1.04E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS19780 2670a05f9f6273204fcfbf28e8a927f9 319 Gene3D G3DSA:3.40.50.720 2 310 3.7E-32 T 28-03-2018 SMD44_RS19780 2670a05f9f6273204fcfbf28e8a927f9 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 229 9.9E-15 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS11710 8df1673833733d431ea6f757ae31bfc3 294 SMART SM00382 59 243 2.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS11710 8df1673833733d431ea6f757ae31bfc3 294 SUPERFAMILY SSF52540 37 257 6.85E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11710 8df1673833733d431ea6f757ae31bfc3 294 Gene3D G3DSA:3.40.50.300 15 269 4.3E-56 T 28-03-2018 SMD44_RS11710 8df1673833733d431ea6f757ae31bfc3 294 Pfam PF00005 ABC transporter 51 199 6.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 4.8E-6 T 28-03-2018 SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 4.8E-6 T 28-03-2018 SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 4.8E-6 T 28-03-2018 SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 260 285 4.8E-6 T 28-03-2018 SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 418 2.0E-79 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 Gene3D G3DSA:1.20.1250.20 251 475 1.5E-25 T 28-03-2018 SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 SUPERFAMILY SSF103473 247 466 2.22E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 SUPERFAMILY SSF103473 4 199 2.22E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 Gene3D G3DSA:1.20.1250.20 6 203 2.2E-38 T 28-03-2018 SMD44_RS33970 2980f604c82823b6b99f98a48ee86843 480 Pfam PF07690 Major Facilitator Superfamily 17 409 9.7E-58 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS22295 43783ef82be2fdd4dc53921780b55286 427 SMART SM00382 50 202 0.0097 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS22295 43783ef82be2fdd4dc53921780b55286 427 Pfam PF07728 AAA domain (dynein-related subfamily) 53 186 2.7E-9 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SMD44_RS22295 43783ef82be2fdd4dc53921780b55286 427 Gene3D G3DSA:3.40.50.300 36 191 2.0E-20 T 28-03-2018 SMD44_RS22295 43783ef82be2fdd4dc53921780b55286 427 SUPERFAMILY SSF52540 39 228 2.47E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16490 f1536f2611358c265afc173f60aa9ce0 516 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 138 291 5.8E-47 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS16490 f1536f2611358c265afc173f60aa9ce0 516 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 138 292 3.9E-47 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS16490 f1536f2611358c265afc173f60aa9ce0 516 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 399 489 2.5E-11 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD44_RS24675 09602d5141fa547818901d1fa900db0d 435 Gene3D G3DSA:3.40.50.300 188 402 1.8E-13 T 28-03-2018 SMD44_RS24675 09602d5141fa547818901d1fa900db0d 435 SUPERFAMILY SSF52540 74 371 6.31E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS24675 09602d5141fa547818901d1fa900db0d 435 Gene3D G3DSA:3.30.450.90 81 187 9.2E-24 T 28-03-2018 SMD44_RS24675 09602d5141fa547818901d1fa900db0d 435 Pfam PF00437 Type II/IV secretion system protein 89 371 6.2E-45 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMD44_RS31515 5f4c6766475a631e994fb9bb5ff3826e 253 SUPERFAMILY SSF55811 10 171 1.31E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS31515 5f4c6766475a631e994fb9bb5ff3826e 253 SUPERFAMILY SSF46785 176 246 1.96E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31515 5f4c6766475a631e994fb9bb5ff3826e 253 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS31515 5f4c6766475a631e994fb9bb5ff3826e 253 PRINTS PR00502 NUDIX hydrolase family signature 58 73 5.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS31515 5f4c6766475a631e994fb9bb5ff3826e 253 PRINTS PR00502 NUDIX hydrolase family signature 44 58 5.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS31515 5f4c6766475a631e994fb9bb5ff3826e 253 Gene3D G3DSA:3.90.79.10 14 170 7.2E-39 T 28-03-2018 SMD44_RS31515 5f4c6766475a631e994fb9bb5ff3826e 253 Gene3D G3DSA:1.10.10.10 171 244 6.6E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31515 5f4c6766475a631e994fb9bb5ff3826e 253 Pfam PF00293 NUDIX domain 15 138 1.2E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS16075 ab27f201bfe747315c182683f1c92a70 411 Gene3D G3DSA:1.10.510.10 91 317 3.4E-47 T 28-03-2018 SMD44_RS16075 ab27f201bfe747315c182683f1c92a70 411 Gene3D G3DSA:3.30.200.20 2 90 2.1E-16 T 28-03-2018 SMD44_RS16075 ab27f201bfe747315c182683f1c92a70 411 SMART SM00220 9 273 1.9E-61 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS16075 ab27f201bfe747315c182683f1c92a70 411 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS16075 ab27f201bfe747315c182683f1c92a70 411 PIRSF PIRSF000654 8 272 3.4E-26 T 28-03-2018 SMD44_RS16075 ab27f201bfe747315c182683f1c92a70 411 Pfam PF00069 Protein kinase domain 9 262 4.4E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS16075 ab27f201bfe747315c182683f1c92a70 411 SUPERFAMILY SSF56112 6 266 2.23E-66 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS14945 f999ab6403262c70509d8b7b8d1aa697 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.8E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS14945 f999ab6403262c70509d8b7b8d1aa697 201 Gene3D G3DSA:1.10.10.60 2 58 1.1E-18 T 28-03-2018 SMD44_RS14945 f999ab6403262c70509d8b7b8d1aa697 201 Gene3D G3DSA:1.10.357.10 59 198 5.2E-18 T 28-03-2018 SMD44_RS14945 f999ab6403262c70509d8b7b8d1aa697 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS14945 f999ab6403262c70509d8b7b8d1aa697 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS14945 f999ab6403262c70509d8b7b8d1aa697 201 SUPERFAMILY SSF46689 3 70 5.99E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS06740 929a77c560ccba29cfd377a0c224d2d7 146 Gene3D G3DSA:3.30.450.30 15 142 9.2E-41 T 28-03-2018 SMD44_RS06740 929a77c560ccba29cfd377a0c224d2d7 146 Pfam PF03259 Roadblock/LC7 domain 19 110 9.6E-26 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS06740 929a77c560ccba29cfd377a0c224d2d7 146 SUPERFAMILY SSF103196 16 139 1.83E-34 T 28-03-2018 SMD44_RS06740 929a77c560ccba29cfd377a0c224d2d7 146 SMART SM00960 20 110 1.0E-28 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS39760 939c6e651f6f91a98c4f5a82c0c9721f 218 Gene3D G3DSA:3.40.630.30 3 184 7.2E-24 T 28-03-2018 SMD44_RS39760 939c6e651f6f91a98c4f5a82c0c9721f 218 Pfam PF13673 Acetyltransferase (GNAT) domain 89 161 5.4E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS39760 939c6e651f6f91a98c4f5a82c0c9721f 218 SUPERFAMILY SSF55729 3 160 8.83E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS17185 81fac451c05634f53e2f538d51942792 390 Pfam PF13190 PDGLE domain 266 342 5.8E-15 T 28-03-2018 IPR025937 PDGLE domain SMD44_RS17185 81fac451c05634f53e2f538d51942792 390 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 220 2.6E-56 T 28-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 SMD44_RS17185 81fac451c05634f53e2f538d51942792 390 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 263 347 2.0E-19 T 28-03-2018 SMD44_RS08120 aa2023e89c80d88b800890485b720928 331 Gene3D G3DSA:3.10.50.40 197 329 1.0E-29 T 28-03-2018 SMD44_RS08120 aa2023e89c80d88b800890485b720928 331 Gene3D G3DSA:3.10.50.40 22 196 2.0E-29 T 28-03-2018 SMD44_RS08120 aa2023e89c80d88b800890485b720928 331 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 239 328 3.8E-20 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SMD44_RS08120 aa2023e89c80d88b800890485b720928 331 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 91 180 1.4E-22 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SMD44_RS08120 aa2023e89c80d88b800890485b720928 331 SUPERFAMILY SSF54534 53 186 3.93E-30 T 28-03-2018 SMD44_RS08120 aa2023e89c80d88b800890485b720928 331 SUPERFAMILY SSF54534 221 328 2.75E-29 T 28-03-2018 SMD44_RS29310 359048accefdaf894d54772d2d211cd0 259 Gene3D G3DSA:1.10.260.40 84 106 6.0E-10 T 28-03-2018 SMD44_RS29310 359048accefdaf894d54772d2d211cd0 259 Gene3D G3DSA:1.10.357.10 107 248 1.5E-8 T 28-03-2018 SMD44_RS29310 359048accefdaf894d54772d2d211cd0 259 Pfam PF00440 Bacterial regulatory proteins, tetR family 58 102 2.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29310 359048accefdaf894d54772d2d211cd0 259 Gene3D G3DSA:1.10.10.60 43 83 2.3E-12 T 28-03-2018 SMD44_RS29310 359048accefdaf894d54772d2d211cd0 259 SUPERFAMILY SSF46689 48 118 2.44E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS26840 5c7c14aa47e098f10ba1134ec1419e6c 182 Pfam PF04892 VanZ like family 24 142 9.6E-17 T 28-03-2018 IPR006976 VanZ-like SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 142 154 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 Gene3D G3DSA:1.20.140.10 237 401 3.1E-45 T 28-03-2018 SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 141 235 1.3E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 395 2.3E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 Gene3D G3DSA:1.10.540.10 8 138 2.5E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 SUPERFAMILY SSF56645 37 247 2.62E-63 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 Gene3D G3DSA:2.40.110.10 139 236 3.5E-37 T 28-03-2018 SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 136 1.7E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS36260 8aa90ebb481cf4513703375abb30f096 407 SUPERFAMILY SSF47203 246 395 4.67E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS07955 4066de4a2adc6304e059a35dd54d6b00 321 Pfam PF10708 Protein of unknown function (DUF2510) 7 38 4.1E-13 T 28-03-2018 IPR018929 Domain of unknown function DUF2510 SMD44_RS07955 4066de4a2adc6304e059a35dd54d6b00 321 Gene3D G3DSA:3.40.1000.10 141 303 1.3E-13 T 28-03-2018 SMD44_RS42190 3e42e8a40620293f4c13a7e3eb013abe 272 SUPERFAMILY SSF52777 2 140 1.78E-19 T 28-03-2018 SMD44_RS42190 3e42e8a40620293f4c13a7e3eb013abe 272 Gene3D G3DSA:3.30.559.10 1 172 6.1E-19 T 28-03-2018 SMD44_RS42190 3e42e8a40620293f4c13a7e3eb013abe 272 Pfam PF00668 Condensation domain 57 144 1.5E-15 T 28-03-2018 IPR001242 Condensation domain SMD44_RS09280 ea7e7cdba36abbafd86022a931d17ec1 140 SUPERFAMILY SSF141322 72 139 4.58E-6 T 28-03-2018 SMD44_RS09280 ea7e7cdba36abbafd86022a931d17ec1 140 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 139 9.7E-19 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain SMD44_RS09280 ea7e7cdba36abbafd86022a931d17ec1 140 Gene3D G3DSA:2.40.50.140 67 140 3.2E-19 T 28-03-2018 SMD44_RS30820 1c34ec131be152af6b17ae0adc47a36b 181 SUPERFAMILY SSF55729 20 156 1.01E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS30820 1c34ec131be152af6b17ae0adc47a36b 181 Pfam PF00583 Acetyltransferase (GNAT) family 47 151 1.9E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS30820 1c34ec131be152af6b17ae0adc47a36b 181 Gene3D G3DSA:3.40.630.30 6 178 4.3E-20 T 28-03-2018 SMD44_RS16520 b1c15aaf86bdf0e4ff495a66f4657cd2 193 SUPERFAMILY SSF160904 6 166 1.96E-38 T 28-03-2018 SMD44_RS16520 b1c15aaf86bdf0e4ff495a66f4657cd2 193 Pfam PF07336 Putative stress-induced transcription regulator 12 119 1.7E-7 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS16520 b1c15aaf86bdf0e4ff495a66f4657cd2 193 Gene3D G3DSA:1.10.3300.10 4 169 1.1E-37 T 28-03-2018 IPR023286 ABATE domain SMD44_RS16520 b1c15aaf86bdf0e4ff495a66f4657cd2 193 Pfam PF11706 CGNR zinc finger 124 167 1.7E-17 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS15770 1ee9f51867d812a5b96a5863f974f2e1 289 SUPERFAMILY SSF161098 86 272 4.19E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15770 1ee9f51867d812a5b96a5863f974f2e1 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 273 3.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15770 1ee9f51867d812a5b96a5863f974f2e1 289 Gene3D G3DSA:1.10.3720.10 24 284 1.9E-28 T 28-03-2018 SMD44_RS10110 a37d4b95a4ea16474c02ecdd2a896a47 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 71 1.9E-20 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD44_RS10110 a37d4b95a4ea16474c02ecdd2a896a47 76 Pfam PF03840 Preprotein translocase SecG subunit 3 71 2.1E-19 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD44_RS10110 a37d4b95a4ea16474c02ecdd2a896a47 76 PRINTS PR01651 Protein-export SecG membrane protein signature 52 74 2.1E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD44_RS10110 a37d4b95a4ea16474c02ecdd2a896a47 76 PRINTS PR01651 Protein-export SecG membrane protein signature 21 35 2.1E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD44_RS10110 a37d4b95a4ea16474c02ecdd2a896a47 76 PRINTS PR01651 Protein-export SecG membrane protein signature 36 52 2.1E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD44_RS10110 a37d4b95a4ea16474c02ecdd2a896a47 76 PRINTS PR01651 Protein-export SecG membrane protein signature 1 21 2.1E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD44_RS14620 798be9ff1538102d5dedb6651c82b36d 202 Gene3D G3DSA:2.40.50.140 1 116 4.2E-37 T 28-03-2018 SMD44_RS14620 798be9ff1538102d5dedb6651c82b36d 202 SUPERFAMILY SSF50249 5 141 1.61E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS14620 798be9ff1538102d5dedb6651c82b36d 202 Pfam PF00436 Single-strand binding protein family 6 104 2.7E-18 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SMD44_RS14620 798be9ff1538102d5dedb6651c82b36d 202 Hamap MF_00984 Single-stranded DNA-binding protein. 3 110 22.511 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD44_RS23240 25b3f89b3b18bfc21ad05ed4c671f4e8 434 SUPERFAMILY SSF88713 161 391 7.51E-23 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS23240 25b3f89b3b18bfc21ad05ed4c671f4e8 434 SUPERFAMILY SSF88713 89 131 7.51E-23 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS23240 25b3f89b3b18bfc21ad05ed4c671f4e8 434 Gene3D G3DSA:3.20.20.370 78 397 4.2E-37 T 28-03-2018 SMD44_RS15955 3d5639fd76bdb3d51899f64a578ad5b6 208 Pfam PF07336 Putative stress-induced transcription regulator 30 155 5.8E-27 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS15955 3d5639fd76bdb3d51899f64a578ad5b6 208 Pfam PF11706 CGNR zinc finger 161 203 5.6E-17 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS15955 3d5639fd76bdb3d51899f64a578ad5b6 208 Gene3D G3DSA:1.10.3300.10 19 205 5.9E-56 T 28-03-2018 IPR023286 ABATE domain SMD44_RS15955 3d5639fd76bdb3d51899f64a578ad5b6 208 SUPERFAMILY SSF160904 22 202 1.44E-44 T 28-03-2018 SMD44_RS17910 7671502079e28c0ab1da22a83ec22924 551 Gene3D G3DSA:2.30.38.10 359 441 2.6E-26 T 28-03-2018 SMD44_RS17910 7671502079e28c0ab1da22a83ec22924 551 Gene3D G3DSA:3.30.300.30 442 550 2.7E-27 T 28-03-2018 SMD44_RS17910 7671502079e28c0ab1da22a83ec22924 551 Gene3D G3DSA:3.40.50.980 6 204 2.7E-42 T 28-03-2018 SMD44_RS17910 7671502079e28c0ab1da22a83ec22924 551 Gene3D G3DSA:3.40.50.980 205 358 2.4E-43 T 28-03-2018 SMD44_RS17910 7671502079e28c0ab1da22a83ec22924 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS17910 7671502079e28c0ab1da22a83ec22924 551 SUPERFAMILY SSF56801 8 541 2.88E-147 T 28-03-2018 SMD44_RS17910 7671502079e28c0ab1da22a83ec22924 551 Pfam PF00501 AMP-binding enzyme 15 448 7.0E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS17910 7671502079e28c0ab1da22a83ec22924 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 532 1.3E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS34870 6fba1a1a854ccdeeaaf38bf94d087a35 257 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 216 246 0.006 T 28-03-2018 IPR024412 Lsr2 SMD44_RS34870 6fba1a1a854ccdeeaaf38bf94d087a35 257 Gene3D G3DSA:3.40.50.10190 112 177 0.0025 T 28-03-2018 IPR001357 BRCT domain SMD44_RS34870 6fba1a1a854ccdeeaaf38bf94d087a35 257 Pfam PF11774 Lsr2 198 245 9.4E-6 T 28-03-2018 IPR024412 Lsr2 SMD44_RS34190 209a5942fd83596486a35d050626f619 683 SUPERFAMILY SSF51703 4 505 2.16E-159 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS34190 209a5942fd83596486a35d050626f619 683 Gene3D G3DSA:3.40.50.280 526 677 9.9E-38 T 28-03-2018 SMD44_RS34190 209a5942fd83596486a35d050626f619 683 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 7 509 1.7E-135 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS34190 209a5942fd83596486a35d050626f619 683 Gene3D G3DSA:3.20.20.240 1 505 1.4E-167 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS34190 209a5942fd83596486a35d050626f619 683 Pfam PF01642 Methylmalonyl-CoA mutase 3 503 2.6E-129 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS34190 209a5942fd83596486a35d050626f619 683 Pfam PF02310 B12 binding domain 546 653 3.5E-18 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS34190 209a5942fd83596486a35d050626f619 683 SUPERFAMILY SSF52242 529 666 5.76E-44 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS34190 209a5942fd83596486a35d050626f619 683 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 544 673 1.3E-39 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS06620 3b597528502c10ab45cce84ba713b535 274 Gene3D G3DSA:2.20.28.20 101 130 8.0E-5 T 28-03-2018 SMD44_RS06620 3b597528502c10ab45cce84ba713b535 274 SUPERFAMILY SSF49879 158 268 2.3E-30 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS06620 3b597528502c10ab45cce84ba713b535 274 SMART SM00240 196 247 1.4E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS06620 3b597528502c10ab45cce84ba713b535 274 Pfam PF13240 zinc-ribbon domain 102 123 1.8E-6 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 SMD44_RS06620 3b597528502c10ab45cce84ba713b535 274 Pfam PF00498 FHA domain 198 261 2.5E-18 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS06620 3b597528502c10ab45cce84ba713b535 274 Gene3D G3DSA:2.60.200.20 151 270 1.6E-27 T 28-03-2018 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 Pfam PF01494 FAD binding domain 9 336 1.5E-76 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 339 1.2E-45 T 28-03-2018 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 1.2E-45 T 28-03-2018 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.2E-45 T 28-03-2018 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 303 1.2E-45 T 28-03-2018 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 323 1.2E-45 T 28-03-2018 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.2E-45 T 28-03-2018 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 Gene3D G3DSA:3.50.50.60 1 386 5.0E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 SUPERFAMILY SSF51905 259 367 1.46E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19770 e8c679479857d1b4f8a102519588414f 497 SUPERFAMILY SSF51905 9 170 1.46E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11565 7094727bd794a8757253c14bf7c66fde 218 Gene3D G3DSA:1.10.357.10 75 214 3.9E-25 T 28-03-2018 SMD44_RS11565 7094727bd794a8757253c14bf7c66fde 218 ProSitePatterns PS01081 TetR-type HTH domain signature. 43 74 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS11565 7094727bd794a8757253c14bf7c66fde 218 Gene3D G3DSA:1.10.10.60 2 74 6.7E-20 T 28-03-2018 SMD44_RS11565 7094727bd794a8757253c14bf7c66fde 218 SUPERFAMILY SSF46689 18 101 1.32E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS11565 7094727bd794a8757253c14bf7c66fde 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 2.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11565 7094727bd794a8757253c14bf7c66fde 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 2.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11565 7094727bd794a8757253c14bf7c66fde 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 72 7.5E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 SUPERFAMILY SSF52540 20 220 1.65E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 Gene3D G3DSA:2.40.30.10 231 323 4.9E-19 T 28-03-2018 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 74 89 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 Gene3D G3DSA:3.40.50.300 15 228 2.7E-39 T 28-03-2018 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 PRINTS PR00315 GTP-binding elongation factor signature 117 128 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 PRINTS PR00315 GTP-binding elongation factor signature 154 163 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 PRINTS PR00315 GTP-binding elongation factor signature 101 111 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 PRINTS PR00315 GTP-binding elongation factor signature 81 89 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 PRINTS PR00315 GTP-binding elongation factor signature 22 35 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 Pfam PF00009 Elongation factor Tu GTP binding domain 20 204 1.9E-41 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 SUPERFAMILY SSF50465 328 428 6.71E-25 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 SUPERFAMILY SSF50447 234 324 1.56E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 21 428 5.2E-164 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD44_RS32820 ab290a6d61cde9e2c6a5d02cfd76a3be 451 Gene3D G3DSA:2.40.30.10 325 429 1.8E-21 T 28-03-2018 SMD44_RS15965 444d1cf6f77a9f501a50ffdbf5e5d077 379 SUPERFAMILY SSF69618 12 273 2.75E-57 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS15965 444d1cf6f77a9f501a50ffdbf5e5d077 379 SMART SM00862 297 367 8.1E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS15965 444d1cf6f77a9f501a50ffdbf5e5d077 379 Gene3D G3DSA:3.40.50.10090 171 272 2.4E-14 T 28-03-2018 SMD44_RS15965 444d1cf6f77a9f501a50ffdbf5e5d077 379 SUPERFAMILY SSF46894 282 367 1.25E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS15965 444d1cf6f77a9f501a50ffdbf5e5d077 379 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 266 4.3E-40 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD44_RS15965 444d1cf6f77a9f501a50ffdbf5e5d077 379 Gene3D G3DSA:3.40.50.10090 44 170 1.2E-19 T 28-03-2018 SMD44_RS15965 444d1cf6f77a9f501a50ffdbf5e5d077 379 Pfam PF00486 Transcriptional regulatory protein, C terminal 304 367 5.5E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS15965 444d1cf6f77a9f501a50ffdbf5e5d077 379 Gene3D G3DSA:1.10.10.10 274 374 2.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04080 3dcee935b771d3290c27b2622f9708e7 192 Gene3D G3DSA:3.40.430.10 3 190 8.1E-26 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS04080 3dcee935b771d3290c27b2622f9708e7 192 Pfam PF01872 RibD C-terminal domain 2 184 5.0E-25 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS04080 3dcee935b771d3290c27b2622f9708e7 192 SUPERFAMILY SSF53597 2 191 1.39E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS42890 0b8d3dc404f12d1b523896874d62694d 432 Gene3D G3DSA:1.25.40.10 100 420 1.1E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS42890 0b8d3dc404f12d1b523896874d62694d 432 Gene3D G3DSA:1.10.260.40 3 81 1.8E-4 T 28-03-2018 SMD44_RS42890 0b8d3dc404f12d1b523896874d62694d 432 SUPERFAMILY SSF48452 188 282 1.99E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS38785 5105083550b631cfdc6861ed3018037a 315 SUPERFAMILY SSF53448 5 221 4.22E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS38785 5105083550b631cfdc6861ed3018037a 315 Pfam PF00535 Glycosyl transferase family 2 8 122 1.1E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS38785 5105083550b631cfdc6861ed3018037a 315 Gene3D G3DSA:3.90.550.10 2 229 4.7E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS38430 7c436cbaf9374ecf6d1f61f214d90583 116 Gene3D G3DSA:2.30.130.30 11 114 2.0E-12 T 28-03-2018 SMD44_RS38430 7c436cbaf9374ecf6d1f61f214d90583 116 Pfam PF04266 ASCH domain 16 111 3.1E-6 T 28-03-2018 IPR007374 ASCH domain SMD44_RS38430 7c436cbaf9374ecf6d1f61f214d90583 116 SUPERFAMILY SSF88697 13 113 1.04E-12 T 28-03-2018 IPR015947 PUA-like domain SMD44_RS38430 7c436cbaf9374ecf6d1f61f214d90583 116 SMART SM01022 16 115 3.0E-8 T 28-03-2018 IPR007374 ASCH domain SMD44_RS29300 ce82aa59d79306a5458e9446d3809910 285 SUPERFAMILY SSF47413 11 75 1.51E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS29300 ce82aa59d79306a5458e9446d3809910 285 Pfam PF13560 Helix-turn-helix domain 13 73 2.4E-13 T 28-03-2018 SMD44_RS29300 ce82aa59d79306a5458e9446d3809910 285 SMART SM00530 17 73 3.6E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS29300 ce82aa59d79306a5458e9446d3809910 285 Gene3D G3DSA:1.10.3100.10 9 168 4.4E-10 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS22195 dc54a302525d1b2cc6f79b59e9150dc3 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 162 1.7E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22195 dc54a302525d1b2cc6f79b59e9150dc3 181 SUPERFAMILY SSF88946 5 83 2.83E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22195 dc54a302525d1b2cc6f79b59e9150dc3 181 SUPERFAMILY SSF88659 107 163 2.8E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22195 dc54a302525d1b2cc6f79b59e9150dc3 181 Gene3D G3DSA:1.10.1740.10 2 80 1.8E-11 T 28-03-2018 SMD44_RS22195 dc54a302525d1b2cc6f79b59e9150dc3 181 Gene3D G3DSA:1.10.10.10 107 179 1.9E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22195 dc54a302525d1b2cc6f79b59e9150dc3 181 Pfam PF08281 Sigma-70, region 4 109 159 8.4E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22195 dc54a302525d1b2cc6f79b59e9150dc3 181 Pfam PF04542 Sigma-70 region 2 11 77 2.8E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 Gene3D G3DSA:3.30.540.10 34 179 5.4E-45 T 28-03-2018 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 SUPERFAMILY SSF56655 39 290 1.83E-74 T 28-03-2018 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 Pfam PF00459 Inositol monophosphatase family 38 260 3.3E-57 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 116 129 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 245 259 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 PRINTS PR00377 Inositol monophosphatase superfamily signature 165 188 9.1E-41 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 PRINTS PR00377 Inositol monophosphatase superfamily signature 242 266 9.1E-41 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 PRINTS PR00377 Inositol monophosphatase superfamily signature 74 94 9.1E-41 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 PRINTS PR00377 Inositol monophosphatase superfamily signature 96 112 9.1E-41 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 PRINTS PR00377 Inositol monophosphatase superfamily signature 116 132 9.1E-41 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 232 9.1E-41 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS31705 dd007e4a3c6ea586a6ac3e64cbb4f920 297 Gene3D G3DSA:3.40.190.80 180 295 1.6E-31 T 28-03-2018 SMD44_RS35310 97a745607bd0baf38d9ba7d95f6ee7c9 99 Gene3D G3DSA:3.30.70.1060 1 84 4.7E-15 T 28-03-2018 SMD44_RS35310 97a745607bd0baf38d9ba7d95f6ee7c9 99 Pfam PF03795 YCII-related domain 1 81 4.8E-15 T 28-03-2018 IPR005545 YCII-related SMD44_RS35310 97a745607bd0baf38d9ba7d95f6ee7c9 99 SUPERFAMILY SSF54909 1 83 1.1E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS12390 a1794ea467887359181e3950bdbfa56d 174 Pfam PF00293 NUDIX domain 26 143 1.8E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS12390 a1794ea467887359181e3950bdbfa56d 174 PRINTS PR00502 NUDIX hydrolase family signature 52 66 1.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS12390 a1794ea467887359181e3950bdbfa56d 174 PRINTS PR00502 NUDIX hydrolase family signature 66 81 1.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS12390 a1794ea467887359181e3950bdbfa56d 174 Gene3D G3DSA:3.90.79.10 14 167 6.4E-24 T 28-03-2018 SMD44_RS12390 a1794ea467887359181e3950bdbfa56d 174 ProSitePatterns PS00893 Nudix box signature. 57 78 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS12390 a1794ea467887359181e3950bdbfa56d 174 SUPERFAMILY SSF55811 16 156 2.17E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 Gene3D G3DSA:3.40.50.850 1 210 4.2E-50 T 28-03-2018 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 PIRSF PIRSF001111 1 210 1.5E-93 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 Pfam PF00857 Isochorismatase family 32 204 1.2E-39 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 PRINTS PR01398 Isochorismatase signature 80 99 1.7E-46 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 PRINTS PR01398 Isochorismatase signature 168 186 1.7E-46 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 PRINTS PR01398 Isochorismatase signature 112 134 1.7E-46 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 PRINTS PR01398 Isochorismatase signature 2 14 1.7E-46 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 PRINTS PR01398 Isochorismatase signature 63 80 1.7E-46 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 PRINTS PR01398 Isochorismatase signature 186 203 1.7E-46 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD44_RS40975 342dba3203f7b0acc5da810a4081f287 210 SUPERFAMILY SSF52499 1 208 7.98E-66 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS17200 9aa807ebaa3c06b07113ac43da694bab 197 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 190 9.2E-29 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS17200 9aa807ebaa3c06b07113ac43da694bab 197 Gene3D G3DSA:1.10.10.60 2 62 4.3E-15 T 28-03-2018 SMD44_RS17200 9aa807ebaa3c06b07113ac43da694bab 197 SUPERFAMILY SSF46689 9 71 1.85E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS17200 9aa807ebaa3c06b07113ac43da694bab 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 8.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS17200 9aa807ebaa3c06b07113ac43da694bab 197 SUPERFAMILY SSF48498 82 193 2.61E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS17200 9aa807ebaa3c06b07113ac43da694bab 197 Gene3D G3DSA:1.10.357.10 63 196 3.2E-17 T 28-03-2018 SMD44_RS34555 6f001749110af94473d56afe716b4089 303 Pfam PF12706 Beta-lactamase superfamily domain 48 269 8.7E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS34555 6f001749110af94473d56afe716b4089 303 Gene3D G3DSA:3.60.15.10 1 303 3.5E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS34555 6f001749110af94473d56afe716b4089 303 SUPERFAMILY SSF56281 1 303 1.49E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS34555 6f001749110af94473d56afe716b4089 303 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 303 92.295 T 28-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 SMD44_RS15425 87db5ce5a533a13af6152b1ae99dd14c 360 Gene3D G3DSA:3.30.360.10 142 360 2.8E-44 T 28-03-2018 SMD44_RS15425 87db5ce5a533a13af6152b1ae99dd14c 360 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 128 5.1E-24 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS15425 87db5ce5a533a13af6152b1ae99dd14c 360 Gene3D G3DSA:3.40.50.720 1 141 7.9E-35 T 28-03-2018 SMD44_RS15425 87db5ce5a533a13af6152b1ae99dd14c 360 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 226 4.2E-13 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS15425 87db5ce5a533a13af6152b1ae99dd14c 360 SUPERFAMILY SSF55347 137 286 7.68E-28 T 28-03-2018 SMD44_RS15425 87db5ce5a533a13af6152b1ae99dd14c 360 SUPERFAMILY SSF51735 6 165 1.03E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS43350 945b81bc89e7ea858edce2c5208c21ba 485 Pfam PF12224 Putative amidoligase enzyme 249 330 5.3E-8 T 28-03-2018 IPR022025 Putative amidoligase enzyme SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 Gene3D G3DSA:1.10.10.60 201 256 2.0E-8 T 28-03-2018 SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 Pfam PF14525 AraC-binding-like domain 5 189 6.0E-19 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 Pfam PF12833 Helix-turn-helix domain 228 309 7.9E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 SUPERFAMILY SSF46689 258 311 5.78E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 Gene3D G3DSA:2.60.120.280 57 191 2.7E-5 T 28-03-2018 SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 276 291 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 291 307 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 SMART SM00342 222 307 1.2E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 Gene3D G3DSA:1.10.10.60 257 315 9.3E-13 T 28-03-2018 SMD44_RS01720 fc668026fe943ed537d3db12bbbbfa13 327 SUPERFAMILY SSF46689 210 255 7.83E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS14040 f7cd4b6bce4fa841aa80e20598adb7e9 519 SUPERFAMILY SSF55154 7 205 5.01E-40 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 SMD44_RS14040 f7cd4b6bce4fa841aa80e20598adb7e9 519 Pfam PF01928 CYTH domain 8 198 1.0E-15 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 SMD44_RS14040 f7cd4b6bce4fa841aa80e20598adb7e9 519 SMART SM00880 235 499 2.0E-63 T 28-03-2018 IPR007899 CHAD domain SMD44_RS14040 f7cd4b6bce4fa841aa80e20598adb7e9 519 Pfam PF05235 CHAD domain 235 467 5.5E-52 T 28-03-2018 IPR007899 CHAD domain SMD44_RS14040 f7cd4b6bce4fa841aa80e20598adb7e9 519 Gene3D G3DSA:2.40.320.10 5 210 2.2E-36 T 28-03-2018 SMD44_RS14040 f7cd4b6bce4fa841aa80e20598adb7e9 519 SMART SM01118 7 205 2.6E-17 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 SMD44_RS27920 0af272a4a2eeed888444124398df20b3 426 Pfam PF01385 Probable transposase 175 290 9.3E-10 T 28-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 SMD44_RS27920 0af272a4a2eeed888444124398df20b3 426 Pfam PF12323 Helix-turn-helix domain 7 46 1.2E-9 T 28-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain SMD44_RS27920 0af272a4a2eeed888444124398df20b3 426 Pfam PF07282 Putative transposase DNA-binding domain 323 386 2.2E-16 T 28-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal SMD44_RS19250 f98b21f761124bdb021da9bea089ef80 167 SUPERFAMILY SSF46785 7 136 1.24E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19250 f98b21f761124bdb021da9bea089ef80 167 Pfam PF01475 Ferric uptake regulator family 15 114 1.3E-23 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMD44_RS19250 f98b21f761124bdb021da9bea089ef80 167 Gene3D G3DSA:1.10.10.10 8 90 7.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 Gene3D G3DSA:3.30.9.10 235 358 2.6E-34 T 28-03-2018 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 423 536 2.4E-18 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 Pfam PF01266 FAD dependent oxidoreductase 38 392 8.0E-49 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 Gene3D G3DSA:3.50.50.60 16 234 1.8E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 SUPERFAMILY SSF51905 437 463 3.98E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 SUPERFAMILY SSF51905 37 263 3.98E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 37 49 1.3E-20 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 352 358 1.3E-20 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 112 124 1.3E-20 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 50 60 1.3E-20 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 66 78 1.3E-20 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS08245 72492d833fb4450c9d4e42419b84384f 539 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 381 393 1.3E-20 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMD44_RS31030 d2e8a4e9efcbf8c9182448bed71a627f 95 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 2.0E-37 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS31030 d2e8a4e9efcbf8c9182448bed71a627f 95 SUPERFAMILY SSF47060 3 89 5.59E-35 T 28-03-2018 IPR009068 S15/NS1, RNA-binding SMD44_RS31030 d2e8a4e9efcbf8c9182448bed71a627f 95 Pfam PF00312 Ribosomal protein S15 8 88 8.9E-37 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS31030 d2e8a4e9efcbf8c9182448bed71a627f 95 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS31030 d2e8a4e9efcbf8c9182448bed71a627f 95 SMART SM01387 8 88 2.5E-51 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS31030 d2e8a4e9efcbf8c9182448bed71a627f 95 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.292 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS31030 d2e8a4e9efcbf8c9182448bed71a627f 95 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 4.0E-37 T 28-03-2018 SMD44_RS31030 d2e8a4e9efcbf8c9182448bed71a627f 95 Gene3D G3DSA:1.10.287.10 2 89 2.5E-34 T 28-03-2018 SMD44_RS19070 3f06557da0925ab869c8862bc51b01c1 166 Gene3D G3DSA:3.30.1460.10 10 142 4.7E-39 T 28-03-2018 SMD44_RS19070 3f06557da0925ab869c8862bc51b01c1 166 Pfam PF10722 Putative bacterial sensory transduction regulator 11 131 4.7E-19 T 28-03-2018 IPR019660 Putative sensory transduction regulator YbjN SMD44_RS19070 3f06557da0925ab869c8862bc51b01c1 166 SUPERFAMILY SSF69635 11 134 2.04E-31 T 28-03-2018 SMD44_RS17875 ebcc56b14e8e4051348918645b54f442 314 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 40 288 6.3E-72 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMD44_RS17875 ebcc56b14e8e4051348918645b54f442 314 Gene3D G3DSA:3.20.20.30 12 255 3.3E-61 T 28-03-2018 SMD44_RS17875 ebcc56b14e8e4051348918645b54f442 314 Pfam PF00296 Luciferase-like monooxygenase 28 245 3.4E-54 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS17875 ebcc56b14e8e4051348918645b54f442 314 SUPERFAMILY SSF51679 23 314 8.64E-67 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS17875 ebcc56b14e8e4051348918645b54f442 314 Gene3D G3DSA:3.20.20.30 256 314 1.1E-6 T 28-03-2018 SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 Pfam PF01965 DJ-1/PfpI family 126 204 7.4E-13 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 SUPERFAMILY SSF46689 247 293 7.77E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 SMART SM00342 259 342 1.1E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 296 338 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 Gene3D G3DSA:1.10.10.60 298 351 1.6E-12 T 28-03-2018 SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 Gene3D G3DSA:1.10.10.60 260 297 1.5E-15 T 28-03-2018 SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 Pfam PF12833 Helix-turn-helix domain 265 343 8.8E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 Gene3D G3DSA:3.40.50.880 26 259 9.3E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 SUPERFAMILY SSF46689 295 346 2.42E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS15535 302ee20d0ac2bd39d20819aaef2b005c 357 SUPERFAMILY SSF52317 30 225 6.54E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS39640 f0fa5570d3e0f2298637e0fd32ff0701 511 SUPERFAMILY SSF48557 13 495 7.85E-119 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMD44_RS39640 f0fa5570d3e0f2298637e0fd32ff0701 511 Gene3D G3DSA:1.20.200.10 203 503 4.0E-66 T 28-03-2018 SMD44_RS39640 f0fa5570d3e0f2298637e0fd32ff0701 511 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 SMD44_RS39640 f0fa5570d3e0f2298637e0fd32ff0701 511 Gene3D G3DSA:1.10.275.10 10 202 8.3E-49 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal SMD44_RS39640 f0fa5570d3e0f2298637e0fd32ff0701 511 Pfam PF00221 Aromatic amino acid lyase 13 455 7.9E-111 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SMD44_RS28240 678952bb2e08b147876bd8b752d04906 336 Gene3D G3DSA:1.10.40.50 272 336 1.8E-18 T 28-03-2018 SMD44_RS28240 678952bb2e08b147876bd8b752d04906 336 SUPERFAMILY SSF52540 113 331 3.47E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28240 678952bb2e08b147876bd8b752d04906 336 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 325 5.4E-38 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SMD44_RS28240 678952bb2e08b147876bd8b752d04906 336 Gene3D G3DSA:3.40.50.300 112 271 1.1E-20 T 28-03-2018 SMD44_RS28240 678952bb2e08b147876bd8b752d04906 336 Pfam PF03193 RsgA GTPase 96 271 2.5E-41 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 SMD44_RS28240 678952bb2e08b147876bd8b752d04906 336 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 334 26.18 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SMD44_RS22155 cdda293d5214caaf6469a7ca69b3de68 112 Gene3D G3DSA:1.10.1660.10 8 110 4.6E-15 T 28-03-2018 SMD44_RS22155 cdda293d5214caaf6469a7ca69b3de68 112 Pfam PF13411 MerR HTH family regulatory protein 18 79 2.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS22155 cdda293d5214caaf6469a7ca69b3de68 112 SUPERFAMILY SSF46955 18 100 2.52E-10 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS22155 cdda293d5214caaf6469a7ca69b3de68 112 SMART SM00422 18 86 5.5E-4 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS04840 3c0943b36bc090dea11e0db5f3402f7e 300 Gene3D G3DSA:3.60.10.10 41 300 9.2E-38 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS04840 3c0943b36bc090dea11e0db5f3402f7e 300 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 49 291 1.7E-9 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS04840 3c0943b36bc090dea11e0db5f3402f7e 300 SUPERFAMILY SSF56219 45 296 3.27E-39 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS36190 9b74e0e1762f38c5695c26268a839203 283 SUPERFAMILY SSF53474 30 258 1.29E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36190 9b74e0e1762f38c5695c26268a839203 283 Gene3D G3DSA:3.40.50.1820 26 272 1.6E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36190 9b74e0e1762f38c5695c26268a839203 283 Pfam PF00975 Thioesterase domain 44 259 7.6E-34 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 Pfam PF00842 Alanine racemase, C-terminal domain 250 376 3.7E-40 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 Pfam PF01168 Alanine racemase, N-terminal domain 13 235 4.6E-67 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 SUPERFAMILY SSF51419 13 251 2.76E-66 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 Gene3D G3DSA:3.20.20.10 8 232 5.2E-52 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 165 176 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 304 321 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 208 235 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 31 47 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 128 140 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 67 85 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 283 298 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 266 281 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 PRINTS PR00992 Alanine racemase signature 359 372 4.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 Hamap MF_01201 Alanine racemase. 6 377 31.924 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 TIGRFAM TIGR00492 alr: alanine racemase 10 378 2.3E-93 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 SUPERFAMILY SSF50621 242 379 3.28E-45 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 Gene3D G3DSA:2.40.37.10 233 385 1.6E-59 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS25705 133c7108f071dffe69114108ccd4636f 386 SMART SM01005 250 377 1.4E-58 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS13105 4db673803eb852dba93b490fc98b98ba 287 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 19 253 5.6E-51 T 28-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 SMD44_RS13105 4db673803eb852dba93b490fc98b98ba 287 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 19 61 4.7E-11 T 28-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal SMD44_RS13105 4db673803eb852dba93b490fc98b98ba 287 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 19 253 3.9E-48 T 28-03-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 SMD44_RS37030 91b9888804f71127cf2d9286f55ecc16 389 Pfam PF00534 Glycosyl transferases group 1 191 343 2.4E-29 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS37030 91b9888804f71127cf2d9286f55ecc16 389 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 1 383 1.3E-185 T 28-03-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 SMD44_RS37030 91b9888804f71127cf2d9286f55ecc16 389 SUPERFAMILY SSF53756 8 383 1.61E-83 T 28-03-2018 SMD44_RS37030 91b9888804f71127cf2d9286f55ecc16 389 Gene3D G3DSA:3.40.50.2000 188 366 7.7E-46 T 28-03-2018 SMD44_RS37030 91b9888804f71127cf2d9286f55ecc16 389 Pfam PF13439 Glycosyltransferase Family 4 15 177 1.3E-26 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS37030 91b9888804f71127cf2d9286f55ecc16 389 Gene3D G3DSA:3.40.50.2000 2 187 6.3E-19 T 28-03-2018 SMD44_RS13545 687c79d79c58b5d42da1f85a0faebfb6 262 SMART SM00382 38 232 3.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS13545 687c79d79c58b5d42da1f85a0faebfb6 262 Pfam PF00005 ABC transporter 29 176 6.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS13545 687c79d79c58b5d42da1f85a0faebfb6 262 Gene3D G3DSA:3.40.50.300 10 247 1.9E-52 T 28-03-2018 SMD44_RS13545 687c79d79c58b5d42da1f85a0faebfb6 262 SUPERFAMILY SSF52540 10 239 8.95E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS42990 96d8143cb4eeaf72b6a6d6f38f205ea7 400 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 22 225 6.1E-13 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMD44_RS42990 96d8143cb4eeaf72b6a6d6f38f205ea7 400 SUPERFAMILY SSF52402 3 225 1.82E-30 T 28-03-2018 SMD44_RS42990 96d8143cb4eeaf72b6a6d6f38f205ea7 400 Gene3D G3DSA:3.40.50.620 1 226 2.6E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS42990 96d8143cb4eeaf72b6a6d6f38f205ea7 400 Pfam PF11922 Domain of unknown function (DUF3440) 230 333 5.1E-22 T 28-03-2018 IPR021845 Protein of unknown function DUF3440 SMD44_RS02030 145f5631a10cb87b4ee9ffcb7d6464db 417 SUPERFAMILY SSF53223 89 209 1.6E-32 T 28-03-2018 SMD44_RS02030 145f5631a10cb87b4ee9ffcb7d6464db 417 Gene3D G3DSA:3.40.50.720 211 407 1.2E-36 T 28-03-2018 SMD44_RS02030 145f5631a10cb87b4ee9ffcb7d6464db 417 SUPERFAMILY SSF51735 215 414 1.54E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02030 145f5631a10cb87b4ee9ffcb7d6464db 417 SMART SM00839 215 417 7.5E-45 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS02030 145f5631a10cb87b4ee9ffcb7d6464db 417 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 103 205 7.4E-19 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS02030 145f5631a10cb87b4ee9ffcb7d6464db 417 Gene3D G3DSA:3.40.50.10860 79 210 1.4E-37 T 28-03-2018 SMD44_RS02030 145f5631a10cb87b4ee9ffcb7d6464db 417 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 296 363 3.9E-9 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS02030 145f5631a10cb87b4ee9ffcb7d6464db 417 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 220 270 4.1E-5 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Pfam PF01839 FG-GAP repeat 102 139 7.0E-8 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Pfam PF01839 FG-GAP repeat 40 67 1.7E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Pfam PF01839 FG-GAP repeat 425 457 3.0E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Pfam PF01839 FG-GAP repeat 346 384 5.5E-9 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Gene3D G3DSA:2.60.40.680 118 190 8.9E-13 T 28-03-2018 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Gene3D G3DSA:2.60.40.680 23 117 4.2E-20 T 28-03-2018 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Gene3D G3DSA:2.60.40.680 236 350 5.0E-16 T 28-03-2018 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Gene3D G3DSA:2.130.10.130 351 488 1.1E-19 T 28-03-2018 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 PRINTS PR01185 Integrin alpha subunit signature 423 447 2.6E-5 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 PRINTS PR01185 Integrin alpha subunit signature 339 359 2.6E-5 T 28-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 SUPERFAMILY SSF69318 39 450 2.27E-62 T 28-03-2018 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 218 283 3.2E-8 T 28-03-2018 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 SMART SM00191 159 226 44.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 SMART SM00191 260 330 40.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 SMART SM00191 342 400 3.1E-6 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 SMART SM00191 98 154 6.2E-8 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS22420 93f60da42a44f869c257de9026c08f9b 492 SMART SM00191 421 477 1.1E-8 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS19210 25e2e4e381efbff213070d7a0f1fca65 303 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.6E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19210 25e2e4e381efbff213070d7a0f1fca65 303 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.6E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19210 25e2e4e381efbff213070d7a0f1fca65 303 SUPERFAMILY SSF46785 15 75 2.72E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19210 25e2e4e381efbff213070d7a0f1fca65 303 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 75 3.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19210 25e2e4e381efbff213070d7a0f1fca65 303 SMART SM00345 21 81 3.9E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS19210 25e2e4e381efbff213070d7a0f1fca65 303 Gene3D G3DSA:1.10.10.10 6 83 3.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05100 d453760df967965867c9f9d47c6429a3 149 Gene3D G3DSA:3.30.530.20 1 148 4.2E-24 T 28-03-2018 IPR023393 START-like domain SMD44_RS05100 d453760df967965867c9f9d47c6429a3 149 SUPERFAMILY SSF55961 1 144 6.31E-21 T 28-03-2018 SMD44_RS05100 d453760df967965867c9f9d47c6429a3 149 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 143 1.3E-19 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS32760 282ecf2b76f046eab4cf0aa54635e324 486 SUPERFAMILY SSF53383 108 469 4.35E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS32760 282ecf2b76f046eab4cf0aa54635e324 486 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 90 1.3E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS32760 282ecf2b76f046eab4cf0aa54635e324 486 SUPERFAMILY SSF46785 21 96 1.97E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32760 282ecf2b76f046eab4cf0aa54635e324 486 Pfam PF00155 Aminotransferase class I and II 127 464 2.4E-32 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS32760 282ecf2b76f046eab4cf0aa54635e324 486 SMART SM00345 33 92 2.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS32760 282ecf2b76f046eab4cf0aa54635e324 486 Gene3D G3DSA:1.10.10.10 21 93 6.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32760 282ecf2b76f046eab4cf0aa54635e324 486 Gene3D G3DSA:3.90.1150.10 381 472 1.3E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS32760 282ecf2b76f046eab4cf0aa54635e324 486 Gene3D G3DSA:3.40.640.10 126 380 1.6E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 Gene3D G3DSA:3.30.465.10 353 435 1.5E-20 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 SMART SM01091 358 435 1.8E-16 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 Pfam PF00571 CBS domain 220 273 7.3E-4 T 28-03-2018 IPR000644 CBS domain SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 Pfam PF00571 CBS domain 287 337 2.0E-6 T 28-03-2018 IPR000644 CBS domain SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 SUPERFAMILY SSF54631 211 347 2.02E-26 T 28-03-2018 SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 Gene3D G3DSA:3.20.20.70 61 352 2.4E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 Pfam PF03471 Transporter associated domain 364 433 2.1E-15 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 Pfam PF01595 Domain of unknown function DUF21 11 202 1.0E-36 T 28-03-2018 IPR002550 Domain of unknown function DUF21 SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 SMART SM00116 290 337 42.0 T 28-03-2018 IPR000644 CBS domain SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 SMART SM00116 227 276 0.13 T 28-03-2018 IPR000644 CBS domain SMD44_RS06990 3c018bcb4a3cecde2fd9ea83f42d2ea8 473 SUPERFAMILY SSF56176 363 439 1.17E-15 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS00080 1d4efd3ec82539171f1703ae1393fc43 384 SUPERFAMILY SSF53756 2 383 6.28E-17 T 28-03-2018 SMD44_RS00080 1d4efd3ec82539171f1703ae1393fc43 384 Gene3D G3DSA:3.40.50.2000 19 192 2.4E-6 T 28-03-2018 SMD44_RS00080 1d4efd3ec82539171f1703ae1393fc43 384 Gene3D G3DSA:3.40.50.2000 193 382 5.2E-13 T 28-03-2018 SMD44_RS03110 22308fbc2f3849cd5990274f419ce181 249 Gene3D G3DSA:1.20.910.10 23 248 6.4E-21 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS03110 22308fbc2f3849cd5990274f419ce181 249 SUPERFAMILY SSF48613 36 237 7.48E-17 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS08735 450b155bf56723563e173c902904981b 474 Gene3D G3DSA:3.20.20.80 63 419 1.7E-30 T 28-03-2018 SMD44_RS08735 450b155bf56723563e173c902904981b 474 SUPERFAMILY SSF51445 109 380 7.25E-33 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS08735 450b155bf56723563e173c902904981b 474 Pfam PF01229 Glycosyl hydrolases family 39 122 245 8.1E-7 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 SMD44_RS07695 900221bec648e53b152dd2695ccbf926 215 Gene3D G3DSA:3.40.50.1000 71 202 1.6E-23 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS07695 900221bec648e53b152dd2695ccbf926 215 Gene3D G3DSA:1.10.150.240 22 70 9.7E-13 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS07695 900221bec648e53b152dd2695ccbf926 215 SUPERFAMILY SSF56784 6 199 1.92E-45 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS07695 900221bec648e53b152dd2695ccbf926 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 8 156 3.7E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS07695 900221bec648e53b152dd2695ccbf926 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 8 178 1.9E-19 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS07695 900221bec648e53b152dd2695ccbf926 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 178 1.2E-17 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 Gene3D G3DSA:3.40.50.300 326 546 4.8E-37 T 28-03-2018 SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 SUPERFAMILY SSF52540 358 544 1.02E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 Gene3D G3DSA:3.40.50.300 1 325 1.4E-45 T 28-03-2018 SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 Pfam PF00005 ABC transporter 367 495 2.9E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 Pfam PF00005 ABC transporter 22 187 1.1E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 SMART SM00382 374 541 2.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 SMART SM00382 29 232 1.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS35410 282c67d4c8026ca03245e141f7eb772b 547 SUPERFAMILY SSF52540 4 229 1.28E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS42745 bdb52fc1190b600a71902c4bf347b8b1 218 SUPERFAMILY SSF52540 2 210 3.62E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS42745 bdb52fc1190b600a71902c4bf347b8b1 218 Gene3D G3DSA:3.40.50.300 1 213 2.5E-16 T 28-03-2018 SMD44_RS42745 bdb52fc1190b600a71902c4bf347b8b1 218 Pfam PF02223 Thymidylate kinase 3 197 5.2E-8 T 28-03-2018 SMD44_RS24215 17431d2ff9e4a7ddad5be3e312bd52bf 482 Gene3D G3DSA:2.40.10.10 2 98 2.0E-7 T 28-03-2018 SMD44_RS24215 17431d2ff9e4a7ddad5be3e312bd52bf 482 SUPERFAMILY SSF69318 216 463 5.75E-14 T 28-03-2018 SMD44_RS24215 17431d2ff9e4a7ddad5be3e312bd52bf 482 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 232 295 2.7E-6 T 28-03-2018 SMD44_RS24215 17431d2ff9e4a7ddad5be3e312bd52bf 482 Gene3D G3DSA:2.130.10.130 316 467 2.0E-7 T 28-03-2018 SMD44_RS24215 17431d2ff9e4a7ddad5be3e312bd52bf 482 Gene3D G3DSA:2.40.10.10 99 204 1.5E-20 T 28-03-2018 SMD44_RS24215 17431d2ff9e4a7ddad5be3e312bd52bf 482 SUPERFAMILY SSF50494 3 201 3.16E-14 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS16440 18d8542966a6f41985038fd3a7b924db 318 Gene3D G3DSA:3.40.50.10680 94 318 3.5E-52 T 28-03-2018 SMD44_RS16440 18d8542966a6f41985038fd3a7b924db 318 Gene3D G3DSA:3.40.50.10680 3 78 1.5E-14 T 28-03-2018 SMD44_RS16440 18d8542966a6f41985038fd3a7b924db 318 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 309 2.1E-133 T 28-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 SMD44_RS16440 18d8542966a6f41985038fd3a7b924db 318 Pfam PF01933 Uncharacterised protein family UPF0052 3 279 3.0E-62 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 SMD44_RS16440 18d8542966a6f41985038fd3a7b924db 318 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 318 138.632 T 28-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 SMD44_RS16440 18d8542966a6f41985038fd3a7b924db 318 SUPERFAMILY SSF142338 3 315 1.31E-85 T 28-03-2018 SMD44_RS27085 7b65ba3b27733e179217b697c9de0d11 236 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 47 202 3.4E-62 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD44_RS27085 7b65ba3b27733e179217b697c9de0d11 236 Pfam PF01625 Peptide methionine sulfoxide reductase 49 202 1.5E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD44_RS27085 7b65ba3b27733e179217b697c9de0d11 236 Gene3D G3DSA:3.30.1060.10 27 209 9.1E-74 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD44_RS27085 7b65ba3b27733e179217b697c9de0d11 236 SUPERFAMILY SSF55068 25 209 2.49E-74 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD44_RS27085 7b65ba3b27733e179217b697c9de0d11 236 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 45 208 37.26 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD44_RS20550 a54f07664a9763da3621d81b6df0051e 707 Gene3D G3DSA:3.40.50.300 293 549 2.8E-6 T 28-03-2018 SMD44_RS20550 a54f07664a9763da3621d81b6df0051e 707 SUPERFAMILY SSF52540 348 546 8.63E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20995 fa1c3e7e4571770e27363fd37b5c4487 373 Gene3D G3DSA:3.40.630.30 188 347 2.3E-32 T 28-03-2018 SMD44_RS20995 fa1c3e7e4571770e27363fd37b5c4487 373 SUPERFAMILY SSF55729 186 366 1.06E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS20995 fa1c3e7e4571770e27363fd37b5c4487 373 SUPERFAMILY SSF55729 144 195 2.6E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS20995 fa1c3e7e4571770e27363fd37b5c4487 373 SUPERFAMILY SSF55729 5 115 2.6E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS20995 fa1c3e7e4571770e27363fd37b5c4487 373 Pfam PF02388 FemAB family 266 366 1.3E-17 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 SMD44_RS20995 fa1c3e7e4571770e27363fd37b5c4487 373 Pfam PF02388 FemAB family 8 249 2.9E-27 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 SMD44_RS20995 fa1c3e7e4571770e27363fd37b5c4487 373 Gene3D G3DSA:3.40.630.30 3 187 1.8E-42 T 28-03-2018 SMD44_RS32775 9b0937f323fbfbd10bafe94dca32db46 183 SUPERFAMILY SSF160379 5 181 5.1E-53 T 28-03-2018 SMD44_RS32775 9b0937f323fbfbd10bafe94dca32db46 183 Gene3D G3DSA:3.30.70.1280 4 89 2.1E-32 T 28-03-2018 SMD44_RS32775 9b0937f323fbfbd10bafe94dca32db46 183 Gene3D G3DSA:3.30.70.1260 100 181 4.5E-28 T 28-03-2018 SMD44_RS32775 9b0937f323fbfbd10bafe94dca32db46 183 PIRSF PIRSF008502 3 183 2.2E-49 T 28-03-2018 IPR012545 Protein of unknown function DUF1697 SMD44_RS32775 9b0937f323fbfbd10bafe94dca32db46 183 Pfam PF08002 Protein of unknown function (DUF1697) 5 139 1.6E-42 T 28-03-2018 IPR012545 Protein of unknown function DUF1697 SMD44_RS14675 57ab54b8ef6ed194b3970d19f59953fb 252 Pfam PF13847 Methyltransferase domain 39 176 5.0E-11 T 28-03-2018 IPR025714 Methyltransferase domain SMD44_RS14675 57ab54b8ef6ed194b3970d19f59953fb 252 SUPERFAMILY SSF53335 4 247 1.06E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS14675 57ab54b8ef6ed194b3970d19f59953fb 252 Gene3D G3DSA:3.40.50.150 2 248 2.0E-26 T 28-03-2018 SMD44_RS36360 9549b15f76975e2ff86684d3ea4b4d26 450 Gene3D G3DSA:3.40.33.10 191 312 1.9E-7 T 28-03-2018 IPR014044 CAP domain SMD44_RS36360 9549b15f76975e2ff86684d3ea4b4d26 450 Gene3D G3DSA:3.40.33.10 320 448 8.5E-19 T 28-03-2018 IPR014044 CAP domain SMD44_RS36360 9549b15f76975e2ff86684d3ea4b4d26 450 Gene3D G3DSA:2.60.60.30 17 152 1.3E-25 T 28-03-2018 SMD44_RS36360 9549b15f76975e2ff86684d3ea4b4d26 450 Pfam PF00188 Cysteine-rich secretory protein family 332 448 1.3E-25 T 28-03-2018 IPR014044 CAP domain SMD44_RS36360 9549b15f76975e2ff86684d3ea4b4d26 450 Pfam PF00188 Cysteine-rich secretory protein family 198 312 1.1E-8 T 28-03-2018 IPR014044 CAP domain SMD44_RS36360 9549b15f76975e2ff86684d3ea4b4d26 450 SUPERFAMILY SSF55797 195 316 6.98E-11 T 28-03-2018 IPR014044 CAP domain SMD44_RS36360 9549b15f76975e2ff86684d3ea4b4d26 450 Pfam PF02342 TerD domain 25 153 9.9E-18 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS36360 9549b15f76975e2ff86684d3ea4b4d26 450 SUPERFAMILY SSF55797 328 449 1.19E-25 T 28-03-2018 IPR014044 CAP domain SMD44_RS38435 2ace33014652a8cd56bc262227f2ef42 530 Gene3D G3DSA:2.140.10.10 372 529 2.5E-4 T 28-03-2018 SMD44_RS38435 2ace33014652a8cd56bc262227f2ef42 530 SUPERFAMILY SSF50969 103 306 2.0E-8 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMD44_RS38435 2ace33014652a8cd56bc262227f2ef42 530 SUPERFAMILY SSF50969 231 516 1.18E-5 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMD44_RS38435 2ace33014652a8cd56bc262227f2ef42 530 Gene3D G3DSA:2.130.10.120 80 326 1.2E-5 T 28-03-2018 SMD44_RS12830 4a0151d8377ba154266604bc0d8e2a58 344 Gene3D G3DSA:3.90.180.10 7 155 2.4E-41 T 28-03-2018 SMD44_RS12830 4a0151d8377ba154266604bc0d8e2a58 344 Gene3D G3DSA:3.40.50.720 156 284 1.8E-30 T 28-03-2018 SMD44_RS12830 4a0151d8377ba154266604bc0d8e2a58 344 SUPERFAMILY SSF50129 11 148 6.02E-40 T 28-03-2018 IPR011032 GroES-like SMD44_RS12830 4a0151d8377ba154266604bc0d8e2a58 344 Pfam PF00107 Zinc-binding dehydrogenase 165 293 7.5E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS12830 4a0151d8377ba154266604bc0d8e2a58 344 Pfam PF16884 N-terminal domain of oxidoreductase 13 115 9.7E-39 T 28-03-2018 SMD44_RS12830 4a0151d8377ba154266604bc0d8e2a58 344 SUPERFAMILY SSF51735 130 307 1.25E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS12830 4a0151d8377ba154266604bc0d8e2a58 344 SMART SM00829 25 340 2.6E-8 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS07215 3a4913cb0a0d2646b8375462152aa4ae 716 Hamap MF_00983 Probable primosomal protein N' [priA]. 56 715 20.774 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SMD44_RS07215 3a4913cb0a0d2646b8375462152aa4ae 716 Gene3D G3DSA:3.40.50.300 214 359 1.6E-5 T 28-03-2018 SMD44_RS07215 3a4913cb0a0d2646b8375462152aa4ae 716 SUPERFAMILY SSF52540 224 313 7.38E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10695 35e220452a8ed7b790cc2a8f9436355a 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 317 1.1E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS10695 35e220452a8ed7b790cc2a8f9436355a 330 SUPERFAMILY SSF161098 84 316 1.09E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS10695 35e220452a8ed7b790cc2a8f9436355a 330 Gene3D G3DSA:1.10.3720.10 27 320 4.8E-46 T 28-03-2018 SMD44_RS03170 6692d5b51342c9d34002619770a2478d 469 SUPERFAMILY SSF55874 343 466 3.01E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS03170 6692d5b51342c9d34002619770a2478d 469 Pfam PF07730 Histidine kinase 264 338 3.2E-9 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS03170 6692d5b51342c9d34002619770a2478d 469 Pfam PF13796 Putative sensor 42 236 4.4E-31 T 28-03-2018 IPR025828 Putative sensor domain SMD44_RS03170 6692d5b51342c9d34002619770a2478d 469 Gene3D G3DSA:3.30.565.10 225 467 5.0E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS03170 6692d5b51342c9d34002619770a2478d 469 SMART SM00387 371 469 2.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS25080 b99e38db6317983d72e3b11315d8b308 523 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 509 8.4E-178 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25080 b99e38db6317983d72e3b11315d8b308 523 Pfam PF00361 Proton-conducting membrane transporter 139 443 4.8E-68 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25080 b99e38db6317983d72e3b11315d8b308 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 401 427 5.7E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25080 b99e38db6317983d72e3b11315d8b308 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 349 368 5.7E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25080 b99e38db6317983d72e3b11315d8b308 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 186 210 5.7E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25080 b99e38db6317983d72e3b11315d8b308 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 5.7E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25080 b99e38db6317983d72e3b11315d8b308 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 261 285 5.7E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS14860 3e257e62f798597a6af592227c5914dc 308 SUPERFAMILY SSF53850 90 296 8.69E-33 T 28-03-2018 SMD44_RS14860 3e257e62f798597a6af592227c5914dc 308 Gene3D G3DSA:3.40.190.10 91 185 8.5E-20 T 28-03-2018 SMD44_RS14860 3e257e62f798597a6af592227c5914dc 308 SUPERFAMILY SSF46785 2 112 4.81E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14860 3e257e62f798597a6af592227c5914dc 308 Gene3D G3DSA:3.40.190.10 186 271 7.7E-21 T 28-03-2018 SMD44_RS14860 3e257e62f798597a6af592227c5914dc 308 Gene3D G3DSA:1.10.10.10 1 84 2.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14860 3e257e62f798597a6af592227c5914dc 308 Pfam PF03466 LysR substrate binding domain 88 295 4.0E-37 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS14860 3e257e62f798597a6af592227c5914dc 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 6.7E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS31755 2ebdecc6a6e304f8ba67280d945a06ff 554 Pfam PF03814 Potassium-transporting ATPase A subunit 14 552 2.7E-221 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMD44_RS31755 2ebdecc6a6e304f8ba67280d945a06ff 554 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 554 32.125 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMD44_RS31755 2ebdecc6a6e304f8ba67280d945a06ff 554 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 552 3.2E-200 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMD44_RS31755 2ebdecc6a6e304f8ba67280d945a06ff 554 PIRSF PIRSF001294 4 554 2.7E-211 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMD44_RS08645 7144b73f2c97308398b82e2ae9fe44ad 507 SUPERFAMILY SSF103473 54 258 3.53E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08645 7144b73f2c97308398b82e2ae9fe44ad 507 SUPERFAMILY SSF103473 300 496 3.53E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08645 7144b73f2c97308398b82e2ae9fe44ad 507 Pfam PF07690 Major Facilitator Superfamily 75 462 8.8E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS08645 7144b73f2c97308398b82e2ae9fe44ad 507 Gene3D G3DSA:1.20.1250.20 304 505 1.7E-18 T 28-03-2018 SMD44_RS08645 7144b73f2c97308398b82e2ae9fe44ad 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 194 218 5.8E-5 T 28-03-2018 SMD44_RS08645 7144b73f2c97308398b82e2ae9fe44ad 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 164 184 5.8E-5 T 28-03-2018 SMD44_RS08645 7144b73f2c97308398b82e2ae9fe44ad 507 Gene3D G3DSA:1.20.1250.20 64 257 1.1E-27 T 28-03-2018 SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 Gene3D G3DSA:1.10.1660.10 7 65 1.8E-17 T 28-03-2018 SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 Gene3D G3DSA:1.10.1660.10 66 137 2.1E-13 T 28-03-2018 SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 SMART SM00422 11 79 4.1E-24 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 SUPERFAMILY SSF46955 11 132 6.96E-28 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 Pfam PF09278 MerR, DNA binding 53 118 2.4E-18 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 9.1E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 9.1E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 9.1E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 Pfam PF00376 MerR family regulatory protein 12 48 1.7E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS08570 3d387a8cb4ff73aba94adf8abe424c8e 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 149 1.5E-71 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 SMD44_RS15575 452ce4a33c6c9eae2b71cad72f8c1e99 770 SUPERFAMILY SSF53955 35 238 5.34E-63 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS15575 452ce4a33c6c9eae2b71cad72f8c1e99 770 SUPERFAMILY SSF56601 208 227 8.55E-86 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS15575 452ce4a33c6c9eae2b71cad72f8c1e99 770 SUPERFAMILY SSF56601 256 634 8.55E-86 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS15575 452ce4a33c6c9eae2b71cad72f8c1e99 770 Pfam PF00905 Penicillin binding protein transpeptidase domain 326 582 3.9E-31 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS15575 452ce4a33c6c9eae2b71cad72f8c1e99 770 Gene3D G3DSA:3.40.710.10 242 665 1.0E-95 T 28-03-2018 SMD44_RS15575 452ce4a33c6c9eae2b71cad72f8c1e99 770 Gene3D G3DSA:1.10.3810.10 38 239 4.1E-69 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS15575 452ce4a33c6c9eae2b71cad72f8c1e99 770 Pfam PF00912 Transglycosylase 54 223 2.7E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 SMD44_RS10480 a7824ad11426e764e3e5e83d4039e1fc 312 Gene3D G3DSA:1.10.287.100 236 276 3.0E-14 T 28-03-2018 SMD44_RS10480 a7824ad11426e764e3e5e83d4039e1fc 312 SUPERFAMILY SSF159659 25 276 2.09E-71 T 28-03-2018 SMD44_RS10480 a7824ad11426e764e3e5e83d4039e1fc 312 PIRSF PIRSF028754 12 312 7.1E-111 T 28-03-2018 IPR008492 Protein of unknown function DUF774 SMD44_RS10480 a7824ad11426e764e3e5e83d4039e1fc 312 Pfam PF09754 PAC2 family 35 253 7.8E-38 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 SUPERFAMILY SSF51735 22 258 1.87E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 Pfam PF00106 short chain dehydrogenase 28 222 1.5E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 Gene3D G3DSA:3.40.50.720 13 267 1.0E-59 T 28-03-2018 SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 169 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 198 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 217 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 28 45 1.4E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 166 194 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 167 9.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 198 9.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS02150 b5351ab26034cc7330f91023c9c7f8d5 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 103 114 9.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31410 ceef78a940219b9fa6d2205a38b92489 258 Pfam PF13523 Acetyltransferase (GNAT) domain 95 240 1.5E-49 T 28-03-2018 SMD44_RS31410 ceef78a940219b9fa6d2205a38b92489 258 Gene3D G3DSA:3.40.630.30 4 256 2.0E-22 T 28-03-2018 SMD44_RS31410 ceef78a940219b9fa6d2205a38b92489 258 SUPERFAMILY SSF55729 79 252 1.04E-45 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS31410 ceef78a940219b9fa6d2205a38b92489 258 SMART SM01006 91 139 1.6E-13 T 28-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain SMD44_RS28475 681cbd525c65ebcaeba271850db0c342 299 Gene3D G3DSA:3.40.190.10 1 190 1.2E-4 T 28-03-2018 SMD44_RS32205 14db3ab22ba0bd4d08af4c629577f7b0 578 Gene3D G3DSA:3.20.20.140 186 493 5.8E-52 T 28-03-2018 SMD44_RS32205 14db3ab22ba0bd4d08af4c629577f7b0 578 SUPERFAMILY SSF51556 57 98 1.29E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS32205 14db3ab22ba0bd4d08af4c629577f7b0 578 SUPERFAMILY SSF51556 198 510 1.29E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS32205 14db3ab22ba0bd4d08af4c629577f7b0 578 Gene3D G3DSA:3.20.20.140 494 542 0.026 T 28-03-2018 SMD44_RS32205 14db3ab22ba0bd4d08af4c629577f7b0 578 Pfam PF07969 Amidohydrolase family 45 550 5.3E-79 T 28-03-2018 IPR013108 Amidohydrolase 3 SMD44_RS32205 14db3ab22ba0bd4d08af4c629577f7b0 578 Gene3D G3DSA:2.30.40.10 1 100 9.5E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS32205 14db3ab22ba0bd4d08af4c629577f7b0 578 SUPERFAMILY SSF51338 509 551 4.05E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS32205 14db3ab22ba0bd4d08af4c629577f7b0 578 SUPERFAMILY SSF51338 2 57 4.05E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS30460 97e7cc1e670e701ccfe80fcf527dfe90 286 SUPERFAMILY SSF53335 22 214 3.05E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS30460 97e7cc1e670e701ccfe80fcf527dfe90 286 Gene3D G3DSA:3.40.50.150 16 286 5.2E-19 T 28-03-2018 SMD44_RS07645 e0482cb3c536943224842005c5c15bdc 469 SMART SM00220 19 271 1.6E-42 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS07645 e0482cb3c536943224842005c5c15bdc 469 Gene3D G3DSA:3.30.200.20 2 99 1.4E-16 T 28-03-2018 SMD44_RS07645 e0482cb3c536943224842005c5c15bdc 469 SUPERFAMILY SSF56112 15 263 1.48E-59 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS07645 e0482cb3c536943224842005c5c15bdc 469 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 47 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS07645 e0482cb3c536943224842005c5c15bdc 469 Pfam PF00069 Protein kinase domain 20 263 7.7E-39 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS07645 e0482cb3c536943224842005c5c15bdc 469 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS07645 e0482cb3c536943224842005c5c15bdc 469 Gene3D G3DSA:1.10.510.10 100 377 9.0E-39 T 28-03-2018 SMD44_RS26340 4aba58fc731b0bcac7a7bb59226de0d2 161 SUPERFAMILY SSF69118 19 147 9.95E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS26340 4aba58fc731b0bcac7a7bb59226de0d2 161 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 78 1.1E-17 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS26340 4aba58fc731b0bcac7a7bb59226de0d2 161 Gene3D G3DSA:1.20.1290.10 1 151 6.3E-34 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS26340 4aba58fc731b0bcac7a7bb59226de0d2 161 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 96 3.0E-18 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 Gene3D G3DSA:3.30.565.10 285 442 6.3E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 Pfam PF00672 HAMP domain 183 237 1.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 Gene3D G3DSA:1.10.287.130 232 284 9.8E-10 T 28-03-2018 SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 SMART SM00388 242 300 1.3E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 299 2.3E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 SMART SM00304 182 241 4.4E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 SUPERFAMILY SSF158472 183 238 2.35E-5 T 28-03-2018 SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 SMART SM00387 338 444 3.2E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 SUPERFAMILY SSF47384 227 300 6.47E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 SUPERFAMILY SSF55874 289 441 7.99E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28725 8868d65690a5092467e6d1a5c35f208a 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 421 1.2E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS32740 6a1980e8f41af99828574965068caf55 353 Gene3D G3DSA:1.20.1250.20 5 244 8.6E-5 T 28-03-2018 SMD44_RS27725 9600ce3ab7023042cac8c35baca5f3e0 328 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 51 91 1.6E-9 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS27725 9600ce3ab7023042cac8c35baca5f3e0 328 SUPERFAMILY SSF161098 123 313 1.44E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS27725 9600ce3ab7023042cac8c35baca5f3e0 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 144 328 5.7E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS27725 9600ce3ab7023042cac8c35baca5f3e0 328 Gene3D G3DSA:1.10.3720.10 54 317 9.3E-39 T 28-03-2018 SMD44_RS03695 3d74d83972931c853f52d3d39e4103df 589 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 102 498 2.2E-64 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS03695 3d74d83972931c853f52d3d39e4103df 589 SUPERFAMILY SSF53850 53 582 9.41E-85 T 28-03-2018 SMD44_RS03695 3d74d83972931c853f52d3d39e4103df 589 Gene3D G3DSA:3.90.76.10 66 230 8.4E-28 T 28-03-2018 SMD44_RS03695 3d74d83972931c853f52d3d39e4103df 589 Gene3D G3DSA:3.40.190.10 231 333 1.1E-13 T 28-03-2018 SMD44_RS03695 3d74d83972931c853f52d3d39e4103df 589 Gene3D G3DSA:3.10.105.10 334 556 6.5E-32 T 28-03-2018 SMD44_RS03695 3d74d83972931c853f52d3d39e4103df 589 PIRSF PIRSF002741 8 579 7.7E-50 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 96 111 1.6E-14 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 243 255 1.6E-14 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 156 170 1.6E-14 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 106 111 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 SMART SM00020 62 297 1.2E-44 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 SUPERFAMILY SSF50494 50 302 1.73E-49 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 Pfam PF00089 Trypsin 64 297 1.3E-34 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 Gene3D G3DSA:2.40.10.10 63 104 5.0E-13 T 28-03-2018 SMD44_RS12585 7c256e9a4195eda25efaec7a538b6b96 305 Gene3D G3DSA:2.40.10.10 105 305 3.8E-44 T 28-03-2018 SMD44_RS29895 46010e0dfbcdcab1655f9e810b3b4837 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD44_RS29895 46010e0dfbcdcab1655f9e810b3b4837 315 Gene3D G3DSA:3.40.50.720 114 283 2.3E-48 T 28-03-2018 SMD44_RS29895 46010e0dfbcdcab1655f9e810b3b4837 315 SUPERFAMILY SSF52283 40 133 2.07E-7 T 28-03-2018 SMD44_RS29895 46010e0dfbcdcab1655f9e810b3b4837 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 280 4.3E-47 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD44_RS29895 46010e0dfbcdcab1655f9e810b3b4837 315 Gene3D G3DSA:3.40.50.720 32 113 7.9E-16 T 28-03-2018 SMD44_RS29895 46010e0dfbcdcab1655f9e810b3b4837 315 SUPERFAMILY SSF51735 102 281 9.25E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29895 46010e0dfbcdcab1655f9e810b3b4837 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 57 311 6.2E-6 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMD44_RS11590 910a2e7438a7e93fd3af561e4cae0dc2 467 Pfam PF01593 Flavin containing amine oxidoreductase 17 447 2.5E-39 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS11590 910a2e7438a7e93fd3af561e4cae0dc2 467 Gene3D G3DSA:3.50.50.60 2 455 8.3E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11590 910a2e7438a7e93fd3af561e4cae0dc2 467 PRINTS PR00757 Flavin-containing amine oxidase signature 430 447 2.4E-5 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS11590 910a2e7438a7e93fd3af561e4cae0dc2 467 PRINTS PR00757 Flavin-containing amine oxidase signature 9 28 2.4E-5 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD44_RS11590 910a2e7438a7e93fd3af561e4cae0dc2 467 SUPERFAMILY SSF51905 409 452 1.77E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11590 910a2e7438a7e93fd3af561e4cae0dc2 467 SUPERFAMILY SSF51905 7 323 1.77E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 264 280 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 8 483 4.4E-150 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 SUPERFAMILY SSF52283 7 156 8.5E-116 T 28-03-2018 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 SUPERFAMILY SSF52283 194 241 8.5E-116 T 28-03-2018 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 SUPERFAMILY SSF52283 405 484 8.5E-116 T 28-03-2018 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 4 476 50.017 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 SMART SM00997 242 404 2.1E-110 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 SUPERFAMILY SSF51735 242 404 9.18E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 Gene3D G3DSA:3.40.50.1480 261 457 2.6E-84 T 28-03-2018 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 Gene3D G3DSA:3.40.50.1480 1 260 6.2E-94 T 28-03-2018 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 242 404 3.2E-83 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 SMART SM00996 8 483 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 9 476 1.4E-191 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 80 94 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD44_RS16370 2db65e188fcddc25121e8d3f78d8203c 484 PIRSF PIRSF001109 1 484 2.3E-195 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD44_RS03130 2090222defceac00dafe55596e7cd1e2 206 SUPERFAMILY SSF50475 54 205 2.55E-47 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS03130 2090222defceac00dafe55596e7cd1e2 206 Gene3D G3DSA:2.30.110.10 38 206 2.3E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS03130 2090222defceac00dafe55596e7cd1e2 206 SMART SM00903 59 204 1.6E-54 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS03130 2090222defceac00dafe55596e7cd1e2 206 Pfam PF01613 Flavin reductase like domain 59 204 2.2E-37 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 SMART SM00421 59 116 6.1E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 76 92 4.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 62 76 4.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 92 104 4.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 SUPERFAMILY SSF46894 53 121 1.9E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 Gene3D G3DSA:1.10.10.10 51 123 1.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 ProSitePatterns PS00622 LuxR-type HTH domain signature. 76 103 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 Gene3D G3DSA:1.10.10.10 1 39 1.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 SUPERFAMILY SSF46894 1 36 4.42E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 Pfam PF00196 Bacterial regulatory proteins, luxR family 61 116 1.5E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS03145 ab8f8e72fc70218cf7b094999f4fa737 123 Pfam PF00196 Bacterial regulatory proteins, luxR family 1 29 3.2E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 SUPERFAMILY SSF52172 1 177 3.48E-18 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 SMART SM00421 148 210 1.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 Gene3D G3DSA:1.10.10.10 132 215 2.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 Pfam PF00072 Response regulator receiver domain 3 117 2.8E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 Gene3D G3DSA:3.40.50.2300 1 131 9.4E-20 T 28-03-2018 SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 195 5.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11790 dd2de54d4bae78ccd10a67d3b5a0b386 216 SMART SM00448 1 120 3.1E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS12765 cda4bce6537d20374d20b8c2542d49dc 303 Gene3D G3DSA:3.30.70.250 139 181 9.2E-10 T 28-03-2018 SMD44_RS12765 cda4bce6537d20374d20b8c2542d49dc 303 Gene3D G3DSA:3.40.366.10 1 138 6.5E-29 T 28-03-2018 SMD44_RS12765 cda4bce6537d20374d20b8c2542d49dc 303 Gene3D G3DSA:3.40.366.10 182 301 2.8E-28 T 28-03-2018 SMD44_RS12765 cda4bce6537d20374d20b8c2542d49dc 303 SUPERFAMILY SSF55048 124 179 4.71E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD44_RS12765 cda4bce6537d20374d20b8c2542d49dc 303 SUPERFAMILY SSF52151 2 116 2.88E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS12765 cda4bce6537d20374d20b8c2542d49dc 303 SUPERFAMILY SSF52151 179 302 2.88E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS12765 cda4bce6537d20374d20b8c2542d49dc 303 Pfam PF00698 Acyl transferase domain 5 282 1.2E-20 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS12765 cda4bce6537d20374d20b8c2542d49dc 303 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 302 3.9E-20 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS13045 723703539b9c3b3b2b08c2168117bcb2 361 Gene3D G3DSA:1.10.3470.10 25 360 3.0E-67 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS13045 723703539b9c3b3b2b08c2168117bcb2 361 Pfam PF01032 FecCD transport family 41 357 8.2E-92 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS13045 723703539b9c3b3b2b08c2168117bcb2 361 SUPERFAMILY SSF81345 29 357 7.98E-80 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS05165 22062ede6b0e3879d9ceaba1fb790268 265 Gene3D G3DSA:3.30.2140.10 1 165 5.2E-40 T 28-03-2018 SMD44_RS05165 22062ede6b0e3879d9ceaba1fb790268 265 Gene3D G3DSA:3.30.2140.10 166 259 2.2E-20 T 28-03-2018 SMD44_RS05165 22062ede6b0e3879d9ceaba1fb790268 265 Pfam PF00797 N-acetyltransferase 25 251 3.0E-66 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS05165 22062ede6b0e3879d9ceaba1fb790268 265 SUPERFAMILY SSF54001 2 253 9.42E-67 T 28-03-2018 SMD44_RS05165 22062ede6b0e3879d9ceaba1fb790268 265 PRINTS PR01543 Arylamine N-acetyltransferase signature 22 45 1.1E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS05165 22062ede6b0e3879d9ceaba1fb790268 265 PRINTS PR01543 Arylamine N-acetyltransferase signature 70 92 1.1E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS05165 22062ede6b0e3879d9ceaba1fb790268 265 PRINTS PR01543 Arylamine N-acetyltransferase signature 46 69 1.1E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS05165 22062ede6b0e3879d9ceaba1fb790268 265 PRINTS PR01543 Arylamine N-acetyltransferase signature 130 150 1.1E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS05635 2e8442e825865e10de44873b5c66313a 538 Gene3D G3DSA:3.40.50.1820 27 520 3.5E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05635 2e8442e825865e10de44873b5c66313a 538 Pfam PF00561 alpha/beta hydrolase fold 120 498 1.9E-27 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS05635 2e8442e825865e10de44873b5c66313a 538 SUPERFAMILY SSF53474 351 518 4.61E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05635 2e8442e825865e10de44873b5c66313a 538 SUPERFAMILY SSF53474 101 173 4.61E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05635 2e8442e825865e10de44873b5c66313a 538 SUPERFAMILY SSF53474 218 272 4.61E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS07005 a25ea65f7855a3292ee4eb48b67c71b9 90 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 90 19.423 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 SMD44_RS07005 a25ea65f7855a3292ee4eb48b67c71b9 90 Gene3D G3DSA:1.10.287.1080 1 90 1.0E-16 T 28-03-2018 SMD44_RS07005 a25ea65f7855a3292ee4eb48b67c71b9 90 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 90 2.3E-24 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 SMD44_RS07005 a25ea65f7855a3292ee4eb48b67c71b9 90 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 12 89 4.1E-10 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 SMD44_RS07005 a25ea65f7855a3292ee4eb48b67c71b9 90 SUPERFAMILY SSF101386 5 90 9.81E-21 T 28-03-2018 SMD44_RS18620 22cd0eee582e1990d92847992235657e 311 Pfam PF00005 ABC transporter 30 177 2.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS18620 22cd0eee582e1990d92847992235657e 311 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS18620 22cd0eee582e1990d92847992235657e 311 SMART SM00382 38 232 7.5E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS18620 22cd0eee582e1990d92847992235657e 311 Gene3D G3DSA:3.40.50.300 11 252 1.6E-63 T 28-03-2018 SMD44_RS18620 22cd0eee582e1990d92847992235657e 311 SUPERFAMILY SSF52540 14 244 1.09E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13820 5bdeeefd1d51bda70662bd81aa585e0b 644 SMART SM00331 401 643 7.8E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS13820 5bdeeefd1d51bda70662bd81aa585e0b 644 Pfam PF13581 Histidine kinase-like ATPase domain 37 156 4.9E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13820 5bdeeefd1d51bda70662bd81aa585e0b 644 Gene3D G3DSA:3.30.565.10 19 168 1.4E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13820 5bdeeefd1d51bda70662bd81aa585e0b 644 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 430 642 8.4E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS13820 5bdeeefd1d51bda70662bd81aa585e0b 644 SUPERFAMILY SSF55874 64 162 5.42E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13820 5bdeeefd1d51bda70662bd81aa585e0b 644 Gene3D G3DSA:3.60.40.10 382 644 4.0E-33 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS13820 5bdeeefd1d51bda70662bd81aa585e0b 644 SUPERFAMILY SSF55781 302 382 9.16E-6 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS13820 5bdeeefd1d51bda70662bd81aa585e0b 644 Gene3D G3DSA:3.30.450.40 204 381 5.3E-24 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS23450 2f7a4f56a7bcc885a8f7d95822fcca35 213 SUPERFAMILY SSF46689 4 85 1.05E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS23450 2f7a4f56a7bcc885a8f7d95822fcca35 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 2.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS23450 2f7a4f56a7bcc885a8f7d95822fcca35 213 SUPERFAMILY SSF48498 81 187 8.9E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS23450 2f7a4f56a7bcc885a8f7d95822fcca35 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS23450 2f7a4f56a7bcc885a8f7d95822fcca35 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 5.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS23450 2f7a4f56a7bcc885a8f7d95822fcca35 213 Gene3D G3DSA:1.10.260.40 39 68 1.2E-11 T 28-03-2018 SMD44_RS23450 2f7a4f56a7bcc885a8f7d95822fcca35 213 Gene3D G3DSA:1.10.357.10 69 194 4.2E-11 T 28-03-2018 SMD44_RS23450 2f7a4f56a7bcc885a8f7d95822fcca35 213 Gene3D G3DSA:1.10.10.60 1 38 3.4E-15 T 28-03-2018 SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 255 5.0E-71 T 28-03-2018 SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.5E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 3.5E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.5E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.5E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.5E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.5E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 SUPERFAMILY SSF51735 14 254 1.33E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 Gene3D G3DSA:3.40.50.720 8 55 1.3E-11 T 28-03-2018 SMD44_RS07970 60375f77fd320009269d52dc5af09d79 262 Gene3D G3DSA:3.40.50.720 56 260 4.6E-59 T 28-03-2018 SMD44_RS22245 9fdd1043d44a56248b5d2d41a88754f4 548 Pfam PF13360 PQQ-like domain 173 302 9.0E-11 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS22245 9fdd1043d44a56248b5d2d41a88754f4 548 SUPERFAMILY SSF50998 173 491 5.89E-14 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS22245 9fdd1043d44a56248b5d2d41a88754f4 548 Gene3D G3DSA:2.140.10.10 321 509 3.0E-7 T 28-03-2018 SMD44_RS22245 9fdd1043d44a56248b5d2d41a88754f4 548 Gene3D G3DSA:2.140.10.10 47 320 1.1E-15 T 28-03-2018 SMD44_RS20310 68196352990724cde2aa9e72f0ad481e 449 Gene3D G3DSA:3.90.550.10 10 268 6.2E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS20310 68196352990724cde2aa9e72f0ad481e 449 Pfam PF04138 GtrA-like protein 300 417 1.7E-9 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMD44_RS20310 68196352990724cde2aa9e72f0ad481e 449 Pfam PF00535 Glycosyl transferase family 2 35 201 2.0E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS20310 68196352990724cde2aa9e72f0ad481e 449 SUPERFAMILY SSF53448 28 244 5.72E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS39785 7eff00076e1e85ce971d8518b1205b7d 82 Gene3D G3DSA:1.10.1200.10 6 81 1.9E-5 T 28-03-2018 SMD44_RS39785 7eff00076e1e85ce971d8518b1205b7d 82 SUPERFAMILY SSF47336 18 79 3.01E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS37130 3fd2e67c79d950119d58d758eeeee1dd 412 SUPERFAMILY SSF53850 22 410 9.83E-65 T 28-03-2018 SMD44_RS37130 3fd2e67c79d950119d58d758eeeee1dd 412 Gene3D G3DSA:3.40.190.10 178 367 1.7E-7 T 28-03-2018 SMD44_RS37130 3fd2e67c79d950119d58d758eeeee1dd 412 Pfam PF01547 Bacterial extracellular solute-binding protein 35 320 1.4E-40 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS37130 3fd2e67c79d950119d58d758eeeee1dd 412 Gene3D G3DSA:3.40.190.10 10 177 1.9E-37 T 28-03-2018 SMD44_RS28600 e0c0b916cf621ae4b6970933d1158e91 246 Gene3D G3DSA:1.10.10.10 142 246 2.4E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28600 e0c0b916cf621ae4b6970933d1158e91 246 SUPERFAMILY SSF52172 13 139 5.98E-42 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS28600 e0c0b916cf621ae4b6970933d1158e91 246 SMART SM00862 170 241 3.0E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS28600 e0c0b916cf621ae4b6970933d1158e91 246 Gene3D G3DSA:3.40.50.2300 6 141 1.3E-37 T 28-03-2018 SMD44_RS28600 e0c0b916cf621ae4b6970933d1158e91 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 171 241 1.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS28600 e0c0b916cf621ae4b6970933d1158e91 246 Pfam PF00072 Response regulator receiver domain 22 130 3.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS28600 e0c0b916cf621ae4b6970933d1158e91 246 SUPERFAMILY SSF46894 147 242 8.5E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS28600 e0c0b916cf621ae4b6970933d1158e91 246 SMART SM00448 20 130 5.3E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16095 5c1e0f5f5474799d521b77bf74ed83cf 417 Gene3D G3DSA:1.10.3720.10 1 417 2.0E-69 T 28-03-2018 SMD44_RS16095 5c1e0f5f5474799d521b77bf74ed83cf 417 SUPERFAMILY SSF161098 37 127 6.32E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS16095 5c1e0f5f5474799d521b77bf74ed83cf 417 SUPERFAMILY SSF161098 270 405 6.32E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS16095 5c1e0f5f5474799d521b77bf74ed83cf 417 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 274 406 3.0E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS11460 37791efd0b5d6df6b07e829f2014da06 264 Gene3D G3DSA:1.20.5.400 88 153 3.2E-5 T 28-03-2018 SMD44_RS11460 37791efd0b5d6df6b07e829f2014da06 264 Pfam PF04012 PspA/IM30 family 3 231 6.9E-29 T 28-03-2018 IPR007157 PspA/IM30 SMD44_RS29190 caa783175e5fe5d00621a9767772adc8 210 SUPERFAMILY SSF46689 14 78 1.13E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29190 caa783175e5fe5d00621a9767772adc8 210 SUPERFAMILY SSF48498 81 205 2.79E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS29190 caa783175e5fe5d00621a9767772adc8 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 197 9.0E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS29190 caa783175e5fe5d00621a9767772adc8 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 68 5.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29190 caa783175e5fe5d00621a9767772adc8 210 Gene3D G3DSA:1.10.10.60 1 69 1.8E-15 T 28-03-2018 SMD44_RS29190 caa783175e5fe5d00621a9767772adc8 210 Gene3D G3DSA:1.10.357.10 70 210 5.2E-31 T 28-03-2018 SMD44_RS29190 caa783175e5fe5d00621a9767772adc8 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29190 caa783175e5fe5d00621a9767772adc8 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS16745 758298056b7cf032d29c8687418d83a8 265 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 118 8.5E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS16745 758298056b7cf032d29c8687418d83a8 265 SUPERFAMILY SSF54593 11 181 2.69E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS16745 758298056b7cf032d29c8687418d83a8 265 Gene3D G3DSA:3.10.180.10 3 131 2.4E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS16745 758298056b7cf032d29c8687418d83a8 265 Gene3D G3DSA:3.10.180.10 132 263 6.4E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS16745 758298056b7cf032d29c8687418d83a8 265 SUPERFAMILY SSF54593 137 257 6.31E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS37575 2a7103ef194e4899ce1e08701433e7b3 90 Pfam PF13302 Acetyltransferase (GNAT) domain 4 51 1.8E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS37575 2a7103ef194e4899ce1e08701433e7b3 90 SUPERFAMILY SSF55729 4 76 2.2E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS37575 2a7103ef194e4899ce1e08701433e7b3 90 Gene3D G3DSA:3.40.630.30 2 84 6.3E-18 T 28-03-2018 SMD44_RS01560 418e4ea9ad24bf3826dee5b3e89349ed 199 Pfam PF01872 RibD C-terminal domain 7 185 1.0E-19 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS01560 418e4ea9ad24bf3826dee5b3e89349ed 199 SUPERFAMILY SSF53597 7 187 6.28E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS01560 418e4ea9ad24bf3826dee5b3e89349ed 199 Gene3D G3DSA:3.40.430.10 7 195 1.3E-29 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS01585 03ffa002fc7687071735fa0a90b860ea 327 SUPERFAMILY SSF53822 23 319 3.61E-57 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS01585 03ffa002fc7687071735fa0a90b860ea 327 Gene3D G3DSA:3.40.50.2300 137 276 5.5E-26 T 28-03-2018 SMD44_RS01585 03ffa002fc7687071735fa0a90b860ea 327 Gene3D G3DSA:3.40.50.2300 20 136 7.4E-23 T 28-03-2018 SMD44_RS01585 03ffa002fc7687071735fa0a90b860ea 327 Pfam PF13407 Periplasmic binding protein domain 24 285 4.0E-49 T 28-03-2018 IPR025997 Periplasmic binding protein SMD44_RS08445 7972f3d02c42f97a3b72acd3176044ec 238 SUPERFAMILY SSF46785 5 74 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08445 7972f3d02c42f97a3b72acd3176044ec 238 SUPERFAMILY SSF48008 96 226 2.43E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS08445 7972f3d02c42f97a3b72acd3176044ec 238 Pfam PF07729 FCD domain 101 220 8.8E-20 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS08445 7972f3d02c42f97a3b72acd3176044ec 238 SMART SM00345 12 70 9.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08445 7972f3d02c42f97a3b72acd3176044ec 238 Gene3D G3DSA:1.20.120.530 93 236 1.8E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS08445 7972f3d02c42f97a3b72acd3176044ec 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 2.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS08445 7972f3d02c42f97a3b72acd3176044ec 238 SMART SM00895 99 223 5.5E-18 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS08445 7972f3d02c42f97a3b72acd3176044ec 238 Gene3D G3DSA:1.10.10.10 1 84 3.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 Pfam PF08220 DeoR-like helix-turn-helix domain 12 63 1.7E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 SUPERFAMILY SSF100950 84 139 4.61E-30 T 28-03-2018 SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 SUPERFAMILY SSF100950 167 248 4.61E-30 T 28-03-2018 SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 Pfam PF00455 DeoR C terminal sensor domain 84 246 4.8E-52 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 SMART SM01134 80 248 1.1E-61 T 28-03-2018 SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 Gene3D G3DSA:3.40.50.1360 76 257 2.2E-42 T 28-03-2018 SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 SUPERFAMILY SSF46785 10 66 1.35E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 3.0E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 3.0E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 Gene3D G3DSA:1.10.10.10 6 75 1.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03990 96f041dd42d71c4cdcc8068d2002bb10 293 SMART SM00420 12 64 2.0E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD44_RS24395 9f23d359061389728543303e479fce59 310 SUPERFAMILY SSF51197 1 298 5.95E-67 T 28-03-2018 SMD44_RS24395 9f23d359061389728543303e479fce59 310 Gene3D G3DSA:2.60.120.330 1 303 2.5E-68 T 28-03-2018 IPR027443 Isopenicillin N synthase-like SMD44_RS24395 9f23d359061389728543303e479fce59 310 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 3 132 2.2E-23 T 28-03-2018 IPR026992 Non-haem dioxygenase N-terminal domain SMD44_RS24395 9f23d359061389728543303e479fce59 310 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 194 269 5.6E-13 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 SMD44_RS26985 cbf8ce573f81da6773fe86b1d519da0a 539 SUPERFAMILY SSF52096 24 275 2.73E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS26985 cbf8ce573f81da6773fe86b1d519da0a 539 SUPERFAMILY SSF52096 262 539 4.02E-89 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS26985 cbf8ce573f81da6773fe86b1d519da0a 539 Gene3D G3DSA:3.90.226.10 10 277 2.2E-85 T 28-03-2018 SMD44_RS26985 cbf8ce573f81da6773fe86b1d519da0a 539 Pfam PF01039 Carboxyl transferase domain 47 537 4.0E-194 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMD44_RS26985 cbf8ce573f81da6773fe86b1d519da0a 539 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 148 166 3.1E-5 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SMD44_RS26985 cbf8ce573f81da6773fe86b1d519da0a 539 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 114 128 3.1E-5 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SMD44_RS26985 cbf8ce573f81da6773fe86b1d519da0a 539 Gene3D G3DSA:3.90.226.10 278 533 1.1E-74 T 28-03-2018 SMD44_RS31750 6c54e2d6371d6effd514acb347488637 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 1.2E-9 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMD44_RS31750 6c54e2d6371d6effd514acb347488637 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 4.4E-9 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMD44_RS13720 cbe276d9ba48adee2f689a9b8a36cb20 286 Gene3D G3DSA:1.10.260.40 4 88 3.3E-13 T 28-03-2018 SMD44_RS13720 cbe276d9ba48adee2f689a9b8a36cb20 286 SMART SM00530 8 85 4.9E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS13720 cbe276d9ba48adee2f689a9b8a36cb20 286 SUPERFAMILY SSF47413 33 82 1.08E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS13720 cbe276d9ba48adee2f689a9b8a36cb20 286 Pfam PF13560 Helix-turn-helix domain 12 88 2.5E-15 T 28-03-2018 SMD44_RS19515 fe3c7af54125ac1503f8f30125fc1d9b 432 Pfam PF07730 Histidine kinase 216 281 5.2E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS19515 fe3c7af54125ac1503f8f30125fc1d9b 432 SUPERFAMILY SSF55874 325 416 1.08E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19515 fe3c7af54125ac1503f8f30125fc1d9b 432 Gene3D G3DSA:3.30.565.10 243 417 1.1E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19515 fe3c7af54125ac1503f8f30125fc1d9b 432 SMART SM00387 325 418 6.4E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 SUPERFAMILY SSF46565 9 111 2.09E-30 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 399 37.062 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 SUPERFAMILY SSF57938 166 241 2.09E-13 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 SUPERFAMILY SSF49493 291 376 5.49E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 Pfam PF00226 DnaJ domain 10 72 1.1E-26 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 Gene3D G3DSA:2.60.260.20 287 397 1.4E-28 T 28-03-2018 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 SUPERFAMILY SSF49493 245 293 2.22E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 SUPERFAMILY SSF49493 146 170 2.22E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 Gene3D G3DSA:1.10.287.110 6 152 1.1E-30 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 382 2.1E-119 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 Gene3D G3DSA:2.60.260.20 218 286 8.7E-11 T 28-03-2018 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 Pfam PF01556 DnaJ C terminal domain 152 365 1.1E-35 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 Gene3D G3DSA:2.60.260.20 153 216 7.2E-11 T 28-03-2018 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 28-03-2018 IPR018253 DnaJ domain, conserved site SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 SMART SM00271 9 67 7.4E-30 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 Pfam PF00684 DnaJ central domain 179 239 4.0E-9 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 PRINTS PR00625 DnaJ domain signature 67 86 2.9E-22 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 PRINTS PR00625 DnaJ domain signature 12 30 2.9E-22 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 PRINTS PR00625 DnaJ domain signature 47 67 2.9E-22 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS22480 5b76c47d4cf83657af23e7d1fa63ba32 399 PRINTS PR00625 DnaJ domain signature 30 45 2.9E-22 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS30260 48c27518372421bc19e20584697c4f2d 226 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 5.0E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS30260 48c27518372421bc19e20584697c4f2d 226 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 5.0E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS30260 48c27518372421bc19e20584697c4f2d 226 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 5.0E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS30260 48c27518372421bc19e20584697c4f2d 226 SMART SM00411 1 89 1.8E-38 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS30260 48c27518372421bc19e20584697c4f2d 226 Pfam PF00216 Bacterial DNA-binding protein 1 88 5.0E-23 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS30260 48c27518372421bc19e20584697c4f2d 226 Gene3D G3DSA:4.10.520.10 1 96 2.5E-25 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD44_RS30260 48c27518372421bc19e20584697c4f2d 226 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SMD44_RS30260 48c27518372421bc19e20584697c4f2d 226 SUPERFAMILY SSF47729 1 92 1.46E-24 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD44_RS36210 8e4c7c1c168ae0bae81b7196a4655566 86 Gene3D G3DSA:1.10.1200.10 1 86 4.1E-9 T 28-03-2018 SMD44_RS36210 8e4c7c1c168ae0bae81b7196a4655566 86 SUPERFAMILY SSF47336 5 81 1.58E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS10940 a8bfc81a0e987ddc854833024f8421ea 189 Pfam PF01738 Dienelactone hydrolase family 3 187 4.3E-16 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SMD44_RS10940 a8bfc81a0e987ddc854833024f8421ea 189 Gene3D G3DSA:3.40.50.1820 3 188 2.0E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS10940 a8bfc81a0e987ddc854833024f8421ea 189 SUPERFAMILY SSF53474 3 187 8.7E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27700 70ac55a75f339838bef9f3a091c2ae78 352 SUPERFAMILY SSF52540 53 327 6.8E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27700 70ac55a75f339838bef9f3a091c2ae78 352 Gene3D G3DSA:3.40.50.300 21 348 4.8E-77 T 28-03-2018 SMD44_RS27700 70ac55a75f339838bef9f3a091c2ae78 352 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 254 318 1.1E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS27700 70ac55a75f339838bef9f3a091c2ae78 352 SMART SM00382 52 252 1.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS27700 70ac55a75f339838bef9f3a091c2ae78 352 Pfam PF00005 ABC transporter 44 202 1.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS27700 70ac55a75f339838bef9f3a091c2ae78 352 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS27700 70ac55a75f339838bef9f3a091c2ae78 352 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 252 331 4.9E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 Gene3D G3DSA:3.40.30.10 1 127 4.4E-36 T 28-03-2018 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 104 4.6E-30 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 PIRSF PIRSF000077 2 106 5.6E-28 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 PIRSF PIRSF000077 103 123 800.0 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 SUPERFAMILY SSF52833 3 105 1.67E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 Pfam PF00085 Thioredoxin 6 102 1.1E-27 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 PRINTS PR00421 Thioredoxin family signature 23 31 5.7E-8 T 28-03-2018 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 PRINTS PR00421 Thioredoxin family signature 31 40 5.7E-8 T 28-03-2018 SMD44_RS37510 bd393534500d026718e4981eaf7af9c9 127 PRINTS PR00421 Thioredoxin family signature 70 81 5.7E-8 T 28-03-2018 SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 SUPERFAMILY SSF46689 210 258 1.52E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 SUPERFAMILY SSF46689 261 312 2.02E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 Pfam PF12833 Helix-turn-helix domain 231 310 8.1E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 SMART SM00342 225 308 6.7E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 Pfam PF01965 DJ-1/PfpI family 7 170 3.3E-25 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 Gene3D G3DSA:1.10.10.60 267 317 1.7E-9 T 28-03-2018 SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 SUPERFAMILY SSF52317 6 190 3.52E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 Gene3D G3DSA:3.40.50.880 1 225 5.8E-63 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS22965 405ef325ea05317a6ea3791db9b347d5 331 Gene3D G3DSA:1.10.10.60 226 266 3.6E-12 T 28-03-2018 SMD44_RS26550 cc89dd469cb76c0efaee7d1ae1bfb1f1 547 Gene3D G3DSA:3.30.70.20 5 211 1.1E-28 T 28-03-2018 SMD44_RS26550 cc89dd469cb76c0efaee7d1ae1bfb1f1 547 SUPERFAMILY SSF54862 1 484 6.7E-151 T 28-03-2018 SMD44_RS26550 cc89dd469cb76c0efaee7d1ae1bfb1f1 547 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 502 8.3E-222 T 28-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 SMD44_RS26550 cc89dd469cb76c0efaee7d1ae1bfb1f1 547 Gene3D G3DSA:3.30.70.20 212 249 3.4E-17 T 28-03-2018 SMD44_RS26550 cc89dd469cb76c0efaee7d1ae1bfb1f1 547 Pfam PF13247 4Fe-4S dicluster domain 189 285 4.8E-35 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS26550 cc89dd469cb76c0efaee7d1ae1bfb1f1 547 Gene3D G3DSA:3.30.70.20 250 378 1.0E-27 T 28-03-2018 SMD44_RS26550 cc89dd469cb76c0efaee7d1ae1bfb1f1 547 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 372 452 2.9E-28 T 28-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 SMD44_RS26550 cc89dd469cb76c0efaee7d1ae1bfb1f1 547 Gene3D G3DSA:1.10.3650.10 379 451 5.6E-29 T 28-03-2018 SMD44_RS41580 0dc6b56f3d15f53e34bd994e551ca16e 262 Gene3D G3DSA:1.20.950.20 1 216 3.0E-46 T 28-03-2018 SMD44_RS41580 0dc6b56f3d15f53e34bd994e551ca16e 262 SUPERFAMILY SSF103501 2 224 1.83E-65 T 28-03-2018 IPR023234 NarG-like domain SMD44_RS41580 0dc6b56f3d15f53e34bd994e551ca16e 262 Pfam PF02665 Nitrate reductase gamma subunit 7 224 4.1E-80 T 28-03-2018 IPR023234 NarG-like domain SMD44_RS41580 0dc6b56f3d15f53e34bd994e551ca16e 262 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 4 224 2.0E-57 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 SMD44_RS34070 3dc42effcf02974a4e90bcd3f399f4f9 425 SUPERFAMILY SSF48264 19 422 1.28E-55 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS34070 3dc42effcf02974a4e90bcd3f399f4f9 425 Gene3D G3DSA:1.10.630.10 27 422 1.7E-36 T 28-03-2018 SMD44_RS34070 3dc42effcf02974a4e90bcd3f399f4f9 425 PRINTS PR00359 B-class P450 signature 312 339 3.3E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS34070 3dc42effcf02974a4e90bcd3f399f4f9 425 PRINTS PR00359 B-class P450 signature 216 238 3.3E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 Gene3D G3DSA:3.40.50.20 191 267 1.0E-16 T 28-03-2018 SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 Gene3D G3DSA:3.40.50.20 268 339 7.0E-5 T 28-03-2018 SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 141 4.8E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 Pfam PF00107 Zinc-binding dehydrogenase 184 306 1.4E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 SUPERFAMILY SSF50129 7 170 2.67E-54 T 28-03-2018 IPR011032 GroES-like SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 Gene3D G3DSA:3.90.180.10 2 190 1.1E-58 T 28-03-2018 SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 SMART SM00829 12 340 2.6E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 SUPERFAMILY SSF51735 147 310 5.34E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS27070 d6682aaee3769a20eee900c851ef9a3e 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 180 191 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 SUPERFAMILY SSF56801 34 528 3.92E-119 T 28-03-2018 SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 42 461 1.6E-95 T 28-03-2018 IPR010071 Amino acid adenylation domain SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 Pfam PF00501 AMP-binding enzyme 29 436 5.8E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 520 2.1E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 Gene3D G3DSA:3.40.50.980 43 182 9.8E-36 T 28-03-2018 SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 Gene3D G3DSA:3.30.300.30 430 535 1.3E-25 T 28-03-2018 SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 Gene3D G3DSA:3.40.50.980 183 337 4.0E-38 T 28-03-2018 SMD44_RS36200 e73676e03f6afbe2895e3f45bb2e10af 547 Gene3D G3DSA:2.30.38.10 338 429 3.6E-12 T 28-03-2018 SMD44_RS13275 c2b4686e07bd68766c2a27d0fc5a1e01 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 129 11.995 T 28-03-2018 IPR022907 VapC family GO:0004540 SMD44_RS13275 c2b4686e07bd68766c2a27d0fc5a1e01 135 Pfam PF01850 PIN domain 4 123 6.9E-11 T 28-03-2018 IPR002716 PIN domain SMD44_RS13275 c2b4686e07bd68766c2a27d0fc5a1e01 135 SUPERFAMILY SSF88723 4 121 9.53E-13 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS13275 c2b4686e07bd68766c2a27d0fc5a1e01 135 Gene3D G3DSA:3.40.50.1010 2 134 7.0E-15 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS10880 fe4f62f8d02ae4d750a575c391a0973a 166 Gene3D G3DSA:3.90.960.10 5 166 1.6E-42 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS10880 fe4f62f8d02ae4d750a575c391a0973a 166 Pfam PF04073 Aminoacyl-tRNA editing domain 42 153 9.9E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS10880 fe4f62f8d02ae4d750a575c391a0973a 166 SUPERFAMILY SSF55826 13 163 1.44E-42 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS10880 fe4f62f8d02ae4d750a575c391a0973a 166 PIRSF PIRSF006181 6 166 7.9E-52 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SMD44_RS10880 fe4f62f8d02ae4d750a575c391a0973a 166 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 13 163 6.3E-55 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 SUPERFAMILY SSF51556 66 348 1.51E-69 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 Gene3D G3DSA:3.20.20.140 83 331 9.3E-41 T 28-03-2018 SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 Hamap MF_00372 Imidazolonepropionase [hutI]. 5 390 42.96 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 SUPERFAMILY SSF51338 14 62 2.16E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 SUPERFAMILY SSF51338 328 390 3.76E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 Pfam PF01979 Amidohydrolase family 65 368 4.9E-21 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 Gene3D G3DSA:2.30.40.10 5 82 5.0E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 TIGRFAM TIGR01224 hutI: imidazolonepropionase 30 388 2.5E-109 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16615 7d504de9be449ca296893a43a47e1143 391 Gene3D G3DSA:2.30.40.10 332 391 6.1E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 Pfam PF00082 Subtilase family 154 383 7.3E-39 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 346 356 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 Pfam PF05922 Peptidase inhibitor I9 60 119 1.3E-4 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 Gene3D G3DSA:3.40.50.200 126 401 3.0E-77 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 SUPERFAMILY SSF54897 53 117 3.17E-5 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 SUPERFAMILY SSF52743 130 389 3.53E-74 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 159 170 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 345 361 3.6E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 192 205 3.6E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 173 3.6E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 196 206 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMD44_RS32770 8bf7332aa9caaa14bd2b83fe164a9230 402 Gene3D G3DSA:3.30.70.80 46 125 1.2E-14 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMD44_RS04540 20d92e0926b89c1ef7b5f3d922caa86b 81 Gene3D G3DSA:1.10.260.40 12 81 8.6E-5 T 28-03-2018 SMD44_RS28710 49998dc6d9c1e07d4931a4ce61b91cf6 484 Gene3D G3DSA:3.90.1310.10 17 140 4.4E-19 T 28-03-2018 SMD44_RS28710 49998dc6d9c1e07d4931a4ce61b91cf6 484 SUPERFAMILY SSF56601 141 483 1.55E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS28710 49998dc6d9c1e07d4931a4ce61b91cf6 484 Gene3D G3DSA:3.40.710.10 141 484 1.7E-82 T 28-03-2018 SMD44_RS28710 49998dc6d9c1e07d4931a4ce61b91cf6 484 Pfam PF00905 Penicillin binding protein transpeptidase domain 155 480 3.8E-61 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS22485 e9bebd2d8f20751e3173c8d323a2ae74 151 SUPERFAMILY SSF46955 20 112 8.24E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS22485 e9bebd2d8f20751e3173c8d323a2ae74 151 SMART SM00422 20 89 1.8E-24 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS22485 e9bebd2d8f20751e3173c8d323a2ae74 151 Gene3D G3DSA:1.10.1660.10 16 75 3.5E-20 T 28-03-2018 SMD44_RS22485 e9bebd2d8f20751e3173c8d323a2ae74 151 ProSitePatterns PS00552 MerR-type HTH domain signature. 23 45 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS22485 e9bebd2d8f20751e3173c8d323a2ae74 151 Gene3D G3DSA:1.20.5.50 76 134 0.0012 T 28-03-2018 SMD44_RS22485 e9bebd2d8f20751e3173c8d323a2ae74 151 Pfam PF13411 MerR HTH family regulatory protein 20 87 1.3E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 Gene3D G3DSA:3.40.50.300 1040 1397 3.9E-12 T 28-03-2018 SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 SUPERFAMILY SSF52540 1077 1222 1.01E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 SUPERFAMILY SSF52540 1340 1396 1.01E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 SMART SM00240 119 170 1.7E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 SMART SM00382 1098 1421 5.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 Gene3D G3DSA:2.60.200.20 95 203 1.0E-24 T 28-03-2018 SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 SUPERFAMILY SSF49879 86 193 8.23E-26 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 Pfam PF01580 FtsK/SpoIIIE family 1087 1140 2.8E-6 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS16085 8bf219b8714101a157353748d64d4348 1513 Pfam PF00498 FHA domain 121 186 1.4E-16 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 SUPERFAMILY SSF56176 336 428 3.27E-11 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 Pfam PF01595 Domain of unknown function DUF21 9 185 6.2E-30 T 28-03-2018 IPR002550 Domain of unknown function DUF21 SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 Gene3D G3DSA:3.20.20.70 121 336 5.0E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 SMART SM01091 337 423 1.8E-13 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 SUPERFAMILY SSF54631 195 337 1.52E-34 T 28-03-2018 SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 Gene3D G3DSA:3.30.465.10 337 423 1.2E-16 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 Pfam PF03471 Transporter associated domain 339 421 1.6E-11 T 28-03-2018 IPR005170 Transporter-associated domain SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 SMART SM00116 274 322 1.6 T 28-03-2018 IPR000644 CBS domain SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 SMART SM00116 209 258 2.9E-4 T 28-03-2018 IPR000644 CBS domain SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 Pfam PF00571 CBS domain 200 256 2.1E-7 T 28-03-2018 IPR000644 CBS domain SMD44_RS13735 34e09de5ca862d706c5de068564ecbc4 435 Pfam PF00571 CBS domain 272 322 4.4E-7 T 28-03-2018 IPR000644 CBS domain SMD44_RS24240 aeab5085e9a86bdcffe9b532e76e2d34 416 Pfam PF07812 TfuA-like protein 48 166 3.7E-39 T 28-03-2018 IPR012924 TfuA-like, core SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 172 1.2E-6 T 28-03-2018 SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 2.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 2.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 2.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 2.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 2.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 Gene3D G3DSA:3.40.50.720 1 40 1.6E-8 T 28-03-2018 SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 Gene3D G3DSA:3.40.50.720 41 235 2.3E-60 T 28-03-2018 SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 232 4.6E-55 T 28-03-2018 SMD44_RS20665 ffe33c59d6929c95e9c25ca61ff9f8bd 235 SUPERFAMILY SSF51735 3 233 1.19E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS37115 258e1432db0547e4adbdb3f12b031a83 243 Pfam PF13649 Methyltransferase domain 40 132 9.6E-18 T 28-03-2018 SMD44_RS37115 258e1432db0547e4adbdb3f12b031a83 243 Gene3D G3DSA:3.40.50.150 2 242 8.7E-31 T 28-03-2018 SMD44_RS37115 258e1432db0547e4adbdb3f12b031a83 243 SUPERFAMILY SSF53335 19 241 2.43E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS15100 ea07853aa4a73081ac5614a0d6cd94b4 479 Gene3D G3DSA:1.25.40.10 197 348 6.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS15100 ea07853aa4a73081ac5614a0d6cd94b4 479 Gene3D G3DSA:1.25.40.10 349 465 4.3E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS15100 ea07853aa4a73081ac5614a0d6cd94b4 479 SUPERFAMILY SSF48452 237 314 2.24E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS26255 fad836384f36e1507e9f031eb82d6687 468 Pfam PF07690 Major Facilitator Superfamily 36 414 9.7E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS26255 fad836384f36e1507e9f031eb82d6687 468 Gene3D G3DSA:1.20.1250.20 264 455 1.3E-10 T 28-03-2018 SMD44_RS26255 fad836384f36e1507e9f031eb82d6687 468 SUPERFAMILY SSF103473 262 450 9.55E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26255 fad836384f36e1507e9f031eb82d6687 468 SUPERFAMILY SSF103473 29 224 9.55E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26255 fad836384f36e1507e9f031eb82d6687 468 Gene3D G3DSA:1.20.1250.20 9 209 7.2E-11 T 28-03-2018 SMD44_RS17670 8171782dc80e632603d2d8b1a4efa89b 277 Pfam PF01965 DJ-1/PfpI family 65 227 9.2E-25 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS17670 8171782dc80e632603d2d8b1a4efa89b 277 SUPERFAMILY SSF52317 65 249 2.78E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS17670 8171782dc80e632603d2d8b1a4efa89b 277 Gene3D G3DSA:3.40.50.880 60 277 2.2E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS16420 30060835ba2ef14ba8ace19143be96bf 494 Gene3D G3DSA:2.60.290.11 374 464 7.2E-10 T 28-03-2018 SMD44_RS16420 30060835ba2ef14ba8ace19143be96bf 494 Gene3D G3DSA:2.60.290.11 253 373 1.8E-29 T 28-03-2018 SMD44_RS16420 30060835ba2ef14ba8ace19143be96bf 494 Gene3D G3DSA:2.60.290.11 133 252 3.9E-23 T 28-03-2018 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 Gene3D G3DSA:1.10.630.10 6 408 1.9E-77 T 28-03-2018 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 SUPERFAMILY SSF48264 12 405 8.38E-89 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 Pfam PF00067 Cytochrome P450 183 372 1.3E-25 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 PRINTS PR00359 B-class P450 signature 286 313 1.4E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 PRINTS PR00359 B-class P450 signature 354 365 1.4E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 PRINTS PR00359 B-class P450 signature 127 143 1.4E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 PRINTS PR00359 B-class P450 signature 269 280 1.4E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 PRINTS PR00359 B-class P450 signature 188 210 1.4E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 PRINTS PR00359 B-class P450 signature 314 329 1.4E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 PRINTS PR00359 B-class P450 signature 345 354 1.4E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS34075 5a4f3362dc2a3618a9074e230cd54769 408 PRINTS PR00359 B-class P450 signature 144 159 1.4E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 SUPERFAMILY SSF53474 4 286 6.71E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 Gene3D G3DSA:3.40.50.1820 4 288 7.0E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 9.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 9.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 Pfam PF00561 alpha/beta hydrolase fold 28 129 3.3E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 PRINTS PR00412 Epoxide hydrolase signature 34 52 9.2E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 PRINTS PR00412 Epoxide hydrolase signature 229 245 9.2E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 PRINTS PR00412 Epoxide hydrolase signature 261 283 9.2E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS29965 f38aa42e54d26c7d94404723f5271c8e 289 PRINTS PR00412 Epoxide hydrolase signature 114 127 9.2E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS14275 2e5cac7bc29ec0bf5ed30501178f6b7b 404 Gene3D G3DSA:3.40.710.10 52 404 4.7E-76 T 28-03-2018 SMD44_RS14275 2e5cac7bc29ec0bf5ed30501178f6b7b 404 Pfam PF00144 Beta-lactamase 67 388 3.2E-58 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS14275 2e5cac7bc29ec0bf5ed30501178f6b7b 404 SUPERFAMILY SSF56601 290 390 1.43E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS14275 2e5cac7bc29ec0bf5ed30501178f6b7b 404 SUPERFAMILY SSF56601 14 259 1.43E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS02090 8cea7021ea584994cb4dd3b59b6eab49 217 Gene3D G3DSA:1.10.10.60 2 65 8.5E-18 T 28-03-2018 SMD44_RS02090 8cea7021ea584994cb4dd3b59b6eab49 217 SUPERFAMILY SSF46689 15 95 9.48E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS02090 8cea7021ea584994cb4dd3b59b6eab49 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 1.4E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02090 8cea7021ea584994cb4dd3b59b6eab49 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 3.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02090 8cea7021ea584994cb4dd3b59b6eab49 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 3.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02090 8cea7021ea584994cb4dd3b59b6eab49 217 Gene3D G3DSA:1.10.357.10 66 210 1.2E-16 T 28-03-2018 SMD44_RS02090 8cea7021ea584994cb4dd3b59b6eab49 217 SUPERFAMILY SSF48498 121 209 6.92E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS20835 d1d9e4bd94173ece1fc3eebc85e1e6d4 541 Gene3D G3DSA:3.60.21.10 249 540 6.4E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS20835 d1d9e4bd94173ece1fc3eebc85e1e6d4 541 SUPERFAMILY SSF56300 270 358 3.61E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS20835 d1d9e4bd94173ece1fc3eebc85e1e6d4 541 SUPERFAMILY SSF56300 390 528 3.61E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS20835 d1d9e4bd94173ece1fc3eebc85e1e6d4 541 PRINTS PR00114 Serine/threonine phosphatase family signature 308 335 8.7E-5 T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS20835 d1d9e4bd94173ece1fc3eebc85e1e6d4 541 PRINTS PR00114 Serine/threonine phosphatase family signature 271 298 8.7E-5 T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS20835 d1d9e4bd94173ece1fc3eebc85e1e6d4 541 Pfam PF00149 Calcineurin-like phosphoesterase 271 487 6.0E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS20655 4237bf9d15f90faa6ba9849b1e779ad5 269 Gene3D G3DSA:3.40.50.720 2 267 3.4E-13 T 28-03-2018 SMD44_RS20655 4237bf9d15f90faa6ba9849b1e779ad5 269 Pfam PF13460 NAD(P)H-binding 6 171 6.2E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS20655 4237bf9d15f90faa6ba9849b1e779ad5 269 SUPERFAMILY SSF51735 3 197 8.2E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS23465 41e4caed0a2e5d476288a4e9debe63fe 180 Pfam PF03551 Transcriptional regulator PadR-like family 12 84 7.0E-15 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS23465 41e4caed0a2e5d476288a4e9debe63fe 180 SUPERFAMILY SSF46785 8 178 8.75E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23465 41e4caed0a2e5d476288a4e9debe63fe 180 Gene3D G3DSA:1.10.10.10 6 94 8.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11370 2ef122006e301154877f06a55dffbbee 550 Gene3D G3DSA:1.20.810.10 31 450 5.4E-107 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 SMD44_RS11370 2ef122006e301154877f06a55dffbbee 550 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 129 302 1.1E-57 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 SMD44_RS11370 2ef122006e301154877f06a55dffbbee 550 SUPERFAMILY SSF81342 28 305 3.61E-64 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SMD44_RS30760 45d1c7e7a35c4faa09250d2ecd70d55c 748 Gene3D G3DSA:3.40.50.300 311 739 1.0E-12 T 28-03-2018 SMD44_RS30760 45d1c7e7a35c4faa09250d2ecd70d55c 748 SUPERFAMILY SSF52540 329 668 9.14E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22625 53b1c92ae8bd1768d739e50d8fafa1da 434 TIGRFAM TIGR01814 kynureninase: kynureninase 32 425 7.8E-77 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMD44_RS22625 53b1c92ae8bd1768d739e50d8fafa1da 434 Gene3D G3DSA:3.90.1150.10 325 432 4.4E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS22625 53b1c92ae8bd1768d739e50d8fafa1da 434 Hamap MF_01970 Kynureninase [kynU]. 5 426 33.846 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMD44_RS22625 53b1c92ae8bd1768d739e50d8fafa1da 434 Gene3D G3DSA:3.40.640.10 64 324 4.1E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS22625 53b1c92ae8bd1768d739e50d8fafa1da 434 SUPERFAMILY SSF53383 30 428 3.78E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS22625 53b1c92ae8bd1768d739e50d8fafa1da 434 PIRSF PIRSF038800 25 431 3.6E-127 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMD44_RS22625 53b1c92ae8bd1768d739e50d8fafa1da 434 Pfam PF00266 Aminotransferase class-V 182 352 1.6E-13 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 Pfam PF00196 Bacterial regulatory proteins, luxR family 313 365 6.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 SMART SM00421 310 367 1.3E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 313 327 1.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 343 355 1.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 327 343 1.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 Gene3D G3DSA:1.10.10.10 242 374 8.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 ProSitePatterns PS00622 LuxR-type HTH domain signature. 327 354 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 SUPERFAMILY SSF46894 303 367 3.4E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS24330 0c9ccdeca2d43bc3178676f10e9353f2 394 Gene3D G3DSA:3.30.450.40 24 189 5.1E-8 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 Gene3D G3DSA:3.40.50.620 3 142 4.6E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 SUPERFAMILY SSF52402 149 286 1.17E-20 T 28-03-2018 SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 Gene3D G3DSA:3.40.50.620 144 288 8.0E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 PRINTS PR01438 Universal stress protein signature 2 20 2.6E-12 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 PRINTS PR01438 Universal stress protein signature 99 111 2.6E-12 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 PRINTS PR01438 Universal stress protein signature 117 139 2.6E-12 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 Pfam PF00582 Universal stress protein family 149 286 6.8E-20 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 Pfam PF00582 Universal stress protein family 5 139 6.5E-23 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS03645 f73fe62cda2b9c693dc08d93bb5144b9 288 SUPERFAMILY SSF52402 4 141 4.94E-27 T 28-03-2018 SMD44_RS16565 02031a4c2157a410ffd3e688d85cd275 225 SMART SM00862 146 222 1.3E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS16565 02031a4c2157a410ffd3e688d85cd275 225 Gene3D G3DSA:1.10.10.10 123 225 2.7E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16565 02031a4c2157a410ffd3e688d85cd275 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 4.1E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS16565 02031a4c2157a410ffd3e688d85cd275 225 SMART SM00448 2 113 1.3E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16565 02031a4c2157a410ffd3e688d85cd275 225 Pfam PF00072 Response regulator receiver domain 4 114 7.5E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16565 02031a4c2157a410ffd3e688d85cd275 225 SUPERFAMILY SSF52172 1 184 7.03E-42 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS16565 02031a4c2157a410ffd3e688d85cd275 225 Gene3D G3DSA:3.40.50.2300 1 122 1.2E-37 T 28-03-2018 SMD44_RS09950 6737d96e53d726d3662cde1d36ee4599 184 SUPERFAMILY SSF88946 2 73 1.57E-7 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS09950 6737d96e53d726d3662cde1d36ee4599 184 Gene3D G3DSA:1.10.1740.10 1 73 4.6E-7 T 28-03-2018 SMD44_RS09950 6737d96e53d726d3662cde1d36ee4599 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 156 3.7E-18 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS09950 6737d96e53d726d3662cde1d36ee4599 184 Pfam PF08281 Sigma-70, region 4 104 154 1.1E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS09950 6737d96e53d726d3662cde1d36ee4599 184 SUPERFAMILY SSF88659 98 157 7.29E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS09950 6737d96e53d726d3662cde1d36ee4599 184 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 160 7.3E-56 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD44_RS09950 6737d96e53d726d3662cde1d36ee4599 184 Gene3D G3DSA:1.10.10.10 74 162 2.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12730 23d670af0f453eba83f82984991c4709 291 Pfam PF09851 Short C-terminal domain 261 288 6.2E-8 T 28-03-2018 IPR018649 SHOCT domain SMD44_RS12730 23d670af0f453eba83f82984991c4709 291 Pfam PF14472 Domain of unknown function (DUF4429) 15 109 2.5E-15 T 28-03-2018 IPR027860 Domain of unknown function DUF4429 SMD44_RS12730 23d670af0f453eba83f82984991c4709 291 Pfam PF14472 Domain of unknown function (DUF4429) 142 232 2.5E-38 T 28-03-2018 IPR027860 Domain of unknown function DUF4429 SMD44_RS05750 15627938a51738a87ad51097ade0c270 122 SUPERFAMILY SSF51278 20 121 1.26E-42 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05750 15627938a51738a87ad51097ade0c270 122 Pfam PF00699 Urease beta subunit 22 118 1.6E-39 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05750 15627938a51738a87ad51097ade0c270 122 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 20 121 7.0E-35 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05750 15627938a51738a87ad51097ade0c270 122 Gene3D G3DSA:2.10.150.10 20 120 2.4E-42 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS05750 15627938a51738a87ad51097ade0c270 122 Hamap MF_01954 Urease subunit beta [ureB]. 20 120 29.814 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD44_RS15595 fc5e0df468c4766970403ec239773a55 155 SUPERFAMILY SSF52833 4 153 1.26E-47 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS15595 fc5e0df468c4766970403ec239773a55 155 Gene3D G3DSA:3.40.30.10 1 153 1.7E-40 T 28-03-2018 SMD44_RS15595 fc5e0df468c4766970403ec239773a55 155 Pfam PF00578 AhpC/TSA family 8 135 2.1E-35 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD44_RS10990 91674755abca3a92c8c29a94f9d387cb 378 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.3E-16 T 28-03-2018 IPR019933 DivIVA domain SMD44_RS10990 91674755abca3a92c8c29a94f9d387cb 378 Gene3D G3DSA:1.10.287.510 22 289 2.1E-5 T 28-03-2018 SMD44_RS10990 91674755abca3a92c8c29a94f9d387cb 378 Pfam PF05103 DivIVA protein 3 64 6.7E-14 T 28-03-2018 IPR007793 DivIVA family SMD44_RS40430 b7093afbf6e801c7785679752280f8ef 262 SMART SM00346 9 100 1.1E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS40430 b7093afbf6e801c7785679752280f8ef 262 SUPERFAMILY SSF55781 75 258 1.13E-50 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS40430 b7093afbf6e801c7785679752280f8ef 262 Pfam PF09339 IclR helix-turn-helix domain 11 59 8.7E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS40430 b7093afbf6e801c7785679752280f8ef 262 Pfam PF01614 Bacterial transcriptional regulator 128 252 3.8E-34 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS40430 b7093afbf6e801c7785679752280f8ef 262 Gene3D G3DSA:1.10.10.10 2 71 2.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40430 b7093afbf6e801c7785679752280f8ef 262 SUPERFAMILY SSF46785 9 84 1.19E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40430 b7093afbf6e801c7785679752280f8ef 262 Gene3D G3DSA:3.30.450.40 78 261 3.2E-51 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 Gene3D G3DSA:1.25.40.10 725 967 5.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 Gene3D G3DSA:1.10.10.10 968 1015 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 Gene3D G3DSA:1.10.150.200 632 682 0.012 T 28-03-2018 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 Pfam PF13191 AAA ATPase domain 14 191 6.3E-30 T 28-03-2018 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 SMART SM00382 38 226 0.0025 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 SUPERFAMILY SSF46894 948 1015 1.77E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 SUPERFAMILY SSF52540 131 240 1.46E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 SUPERFAMILY SSF52540 13 80 1.46E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 SMART SM00421 952 1009 1.7E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 Gene3D G3DSA:1.25.40.10 376 622 0.0068 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 985 997 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 969 985 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 955 969 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 Gene3D G3DSA:1.25.40.10 683 724 9.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 Pfam PF00196 Bacterial regulatory proteins, luxR family 955 1009 1.7E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 SUPERFAMILY SSF48452 572 740 8.86E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS29875 8ac3498a0ae1e8876873fd168b0c65c0 1030 Gene3D G3DSA:3.40.50.300 14 226 4.6E-14 T 28-03-2018 SMD44_RS03425 20a19ffe4f182f780c1da19f372ad3c3 431 Pfam PF00501 AMP-binding enzyme 94 290 4.9E-16 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS03425 20a19ffe4f182f780c1da19f372ad3c3 431 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 12 429 2.6E-213 T 28-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 SMD44_RS03425 20a19ffe4f182f780c1da19f372ad3c3 431 Pfam PF14535 AMP-binding enzyme C-terminal domain 336 429 4.4E-24 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal SMD44_RS03425 20a19ffe4f182f780c1da19f372ad3c3 431 SUPERFAMILY SSF56801 27 385 4.58E-62 T 28-03-2018 SMD44_RS03425 20a19ffe4f182f780c1da19f372ad3c3 431 Gene3D G3DSA:3.40.50.980 85 260 7.9E-21 T 28-03-2018 SMD44_RS03425 20a19ffe4f182f780c1da19f372ad3c3 431 PIRSF PIRSF006444 2 431 3.9E-200 T 28-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 SMD44_RS03425 20a19ffe4f182f780c1da19f372ad3c3 431 Gene3D G3DSA:3.30.300.30 326 429 1.9E-10 T 28-03-2018 SMD44_RS22685 5bbf21e65a226f296021a7bcce819cae 376 Gene3D G3DSA:1.25.40.10 20 364 0.0026 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08840 b4f0369ea2d16437c33e97938026d420 448 Gene3D G3DSA:3.30.565.10 276 411 2.1E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS08840 b4f0369ea2d16437c33e97938026d420 448 SUPERFAMILY SSF55874 281 409 4.45E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS08840 b4f0369ea2d16437c33e97938026d420 448 Pfam PF13581 Histidine kinase-like ATPase domain 314 380 1.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS08840 b4f0369ea2d16437c33e97938026d420 448 Pfam PF07730 Histidine kinase 192 257 1.6E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS34490 15b7f7016a129b6ec54b79c856648774 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 1.6E-51 T 28-03-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 SMD44_RS34490 15b7f7016a129b6ec54b79c856648774 141 Pfam PF02566 OsmC-like protein 44 136 4.7E-18 T 28-03-2018 IPR003718 OsmC/Ohr family SMD44_RS34490 15b7f7016a129b6ec54b79c856648774 141 SUPERFAMILY SSF82784 3 132 1.01E-30 T 28-03-2018 IPR003718 OsmC/Ohr family SMD44_RS34490 15b7f7016a129b6ec54b79c856648774 141 Gene3D G3DSA:3.30.300.20 7 141 2.1E-27 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta SMD44_RS23320 411ca1716823500abc62312bb4587618 517 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 245 251 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD44_RS23320 411ca1716823500abc62312bb4587618 517 SUPERFAMILY SSF53335 175 313 1.75E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS23320 411ca1716823500abc62312bb4587618 517 Pfam PF05175 Methyltransferase small domain 176 294 1.4E-13 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMD44_RS23320 411ca1716823500abc62312bb4587618 517 Gene3D G3DSA:3.40.50.150 160 350 2.9E-23 T 28-03-2018 SMD44_RS17190 f7b92bac8e12ed6686be060f634df508 113 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 111 9.5E-27 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD44_RS29410 2a966e66142cee2a2d05f44755f041ba 114 PRINTS PR00421 Thioredoxin family signature 36 45 9.6E-7 T 28-03-2018 SMD44_RS29410 2a966e66142cee2a2d05f44755f041ba 114 PRINTS PR00421 Thioredoxin family signature 76 87 9.6E-7 T 28-03-2018 SMD44_RS29410 2a966e66142cee2a2d05f44755f041ba 114 PRINTS PR00421 Thioredoxin family signature 28 36 9.6E-7 T 28-03-2018 SMD44_RS29410 2a966e66142cee2a2d05f44755f041ba 114 ProSitePatterns PS00194 Thioredoxin family active site. 29 47 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMD44_RS29410 2a966e66142cee2a2d05f44755f041ba 114 Pfam PF00085 Thioredoxin 11 108 3.6E-25 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMD44_RS29410 2a966e66142cee2a2d05f44755f041ba 114 PIRSF PIRSF000077 6 111 1.3E-32 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD44_RS29410 2a966e66142cee2a2d05f44755f041ba 114 SUPERFAMILY SSF52833 6 110 5.46E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS29410 2a966e66142cee2a2d05f44755f041ba 114 Gene3D G3DSA:3.40.30.10 3 111 6.0E-28 T 28-03-2018 SMD44_RS31130 43477f1f6cb9e1f961beddf677c72ef7 288 Gene3D G3DSA:1.10.260.40 23 109 9.5E-7 T 28-03-2018 SMD44_RS31130 43477f1f6cb9e1f961beddf677c72ef7 288 Pfam PF13413 Helix-turn-helix domain 38 97 4.9E-20 T 28-03-2018 SMD44_RS31130 43477f1f6cb9e1f961beddf677c72ef7 288 Pfam PF13464 Domain of unknown function (DUF4115) 212 279 3.1E-19 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 SMD44_RS02625 75fc89f0bcc39f7b596b279268f4e0d9 335 Pfam PF05231 MASE1 22 294 6.9E-44 T 28-03-2018 IPR007895 MASE1 SMD44_RS21230 4b05ff3d13c0b6b570f356339dbd5dc4 235 Gene3D G3DSA:3.40.50.720 1 235 1.0E-22 T 28-03-2018 SMD44_RS21230 4b05ff3d13c0b6b570f356339dbd5dc4 235 SUPERFAMILY SSF51735 1 234 2.83E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21230 4b05ff3d13c0b6b570f356339dbd5dc4 235 Pfam PF13460 NAD(P)H-binding 7 219 1.0E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS25500 b31c41f7d2d0be5de6723fc85a30ea09 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site SMD44_RS25500 b31c41f7d2d0be5de6723fc85a30ea09 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 5 211 40.295 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25500 b31c41f7d2d0be5de6723fc85a30ea09 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 7 208 1.6E-91 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25500 b31c41f7d2d0be5de6723fc85a30ea09 214 SUPERFAMILY SSF50447 5 212 5.21E-81 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain SMD44_RS25500 b31c41f7d2d0be5de6723fc85a30ea09 214 Pfam PF00297 Ribosomal protein L3 98 186 1.3E-14 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25500 b31c41f7d2d0be5de6723fc85a30ea09 214 Gene3D G3DSA:4.10.960.10 61 169 1.1E-36 T 28-03-2018 SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 28 406 5.8E-99 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 Gene3D G3DSA:3.40.630.10 277 422 7.8E-20 T 28-03-2018 SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 Gene3D G3DSA:3.40.630.10 18 247 2.8E-39 T 28-03-2018 SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 Pfam PF01546 Peptidase family M20/M25/M40 100 413 2.0E-26 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 SUPERFAMILY SSF55031 213 330 1.27E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 SUPERFAMILY SSF53187 329 414 1.96E-63 T 28-03-2018 SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 SUPERFAMILY SSF53187 21 228 1.96E-63 T 28-03-2018 SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 PIRSF PIRSF005962 17 421 1.5E-95 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 SMD44_RS26760 c703f0f31eaa1ca01ba2a305f8b78a76 423 Pfam PF07687 Peptidase dimerisation domain 218 310 1.7E-6 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS38190 bf39c39ab6a75f8d0327dde94f0f4f93 197 Gene3D G3DSA:1.10.357.10 62 195 1.7E-9 T 28-03-2018 SMD44_RS38190 bf39c39ab6a75f8d0327dde94f0f4f93 197 Gene3D G3DSA:1.10.10.60 2 61 8.6E-12 T 28-03-2018 SMD44_RS38190 bf39c39ab6a75f8d0327dde94f0f4f93 197 SUPERFAMILY SSF46689 8 70 1.33E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS38190 bf39c39ab6a75f8d0327dde94f0f4f93 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 6.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS33630 ed1d58c9140d3658a6cc3379a1361f4b 385 Gene3D G3DSA:3.30.420.40 22 151 5.5E-32 T 28-03-2018 SMD44_RS33630 ed1d58c9140d3658a6cc3379a1361f4b 385 ProSitePatterns PS01125 ROK family signature. 166 193 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS33630 ed1d58c9140d3658a6cc3379a1361f4b 385 Pfam PF00480 ROK family 37 347 1.1E-78 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS33630 ed1d58c9140d3658a6cc3379a1361f4b 385 Gene3D G3DSA:3.30.420.40 152 356 3.0E-61 T 28-03-2018 SMD44_RS33630 ed1d58c9140d3658a6cc3379a1361f4b 385 SUPERFAMILY SSF53067 37 348 5.71E-68 T 28-03-2018 SMD44_RS33630 ed1d58c9140d3658a6cc3379a1361f4b 385 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 38 347 3.5E-90 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SMD44_RS29935 2561490371da781b9f507ac57f0bc788 197 Gene3D G3DSA:1.10.10.60 2 53 2.9E-11 T 28-03-2018 SMD44_RS29935 2561490371da781b9f507ac57f0bc788 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29935 2561490371da781b9f507ac57f0bc788 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29935 2561490371da781b9f507ac57f0bc788 197 Gene3D G3DSA:1.10.357.10 54 190 1.2E-15 T 28-03-2018 SMD44_RS29935 2561490371da781b9f507ac57f0bc788 197 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 80 187 1.5E-6 T 28-03-2018 SMD44_RS29935 2561490371da781b9f507ac57f0bc788 197 SUPERFAMILY SSF46689 4 68 6.16E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29935 2561490371da781b9f507ac57f0bc788 197 SUPERFAMILY SSF48498 77 185 2.52E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS29935 2561490371da781b9f507ac57f0bc788 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 3.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 2.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 Pfam PF00072 Response regulator receiver domain 3 115 8.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 SMART SM00421 150 207 1.7E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 Gene3D G3DSA:3.40.50.2300 1 125 1.7E-32 T 28-03-2018 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 Gene3D G3DSA:1.10.10.10 126 216 3.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 7.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 7.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 7.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 SMART SM00448 1 114 4.1E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 SUPERFAMILY SSF52172 1 183 2.26E-31 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS22890 c013021a849e9ed3f2f97ba1df0f8e2f 232 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS18035 bdeaa99f66117e2548c9e67930ab97ec 239 SMART SM00903 50 232 1.2E-55 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS18035 bdeaa99f66117e2548c9e67930ab97ec 239 Pfam PF01613 Flavin reductase like domain 51 232 4.1E-32 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS18035 bdeaa99f66117e2548c9e67930ab97ec 239 SUPERFAMILY SSF50475 94 231 1.62E-38 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS18035 bdeaa99f66117e2548c9e67930ab97ec 239 Gene3D G3DSA:2.30.110.10 38 239 2.0E-47 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS29285 c9a7e5a86e7559ffbebb12178369b46d 172 Gene3D G3DSA:1.10.287.1060 7 100 2.7E-6 T 28-03-2018 SMD44_RS23650 e2f152ef0bf24109decfa7b70c3d1c4d 275 Pfam PF01061 ABC-2 type transporter 25 230 1.7E-22 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS23650 e2f152ef0bf24109decfa7b70c3d1c4d 275 PIRSF PIRSF006648 13 274 1.5E-69 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS41680 19bcea590cd89fa91b6bd31cec55cff2 671 SMART SM00382 439 634 2.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS41680 19bcea590cd89fa91b6bd31cec55cff2 671 SUPERFAMILY SSF90123 85 365 5.36E-10 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS41680 19bcea590cd89fa91b6bd31cec55cff2 671 Gene3D G3DSA:3.40.50.300 399 663 3.5E-62 T 28-03-2018 SMD44_RS41680 19bcea590cd89fa91b6bd31cec55cff2 671 Pfam PF00005 ABC transporter 430 588 1.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS41680 19bcea590cd89fa91b6bd31cec55cff2 671 SUPERFAMILY SSF52540 406 658 1.36E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS41680 19bcea590cd89fa91b6bd31cec55cff2 671 ProSitePatterns PS00211 ABC transporters family signature. 557 571 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS41680 19bcea590cd89fa91b6bd31cec55cff2 671 Gene3D G3DSA:1.20.1560.10 69 370 4.3E-8 T 28-03-2018 SMD44_RS09845 fdc243ea8296dcc6288b3bb2e9093aa2 456 Gene3D G3DSA:3.40.190.10 42 223 3.5E-38 T 28-03-2018 SMD44_RS09845 fdc243ea8296dcc6288b3bb2e9093aa2 456 Gene3D G3DSA:3.40.190.10 224 394 8.2E-13 T 28-03-2018 SMD44_RS09845 fdc243ea8296dcc6288b3bb2e9093aa2 456 SUPERFAMILY SSF53850 28 449 8.03E-73 T 28-03-2018 SMD44_RS09845 fdc243ea8296dcc6288b3bb2e9093aa2 456 Pfam PF01547 Bacterial extracellular solute-binding protein 55 347 3.0E-53 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS33030 2ad726877b23a2dbfe273ea6e463d5f7 201 Gene3D G3DSA:1.10.150.120 118 201 7.0E-32 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS33030 2ad726877b23a2dbfe273ea6e463d5f7 201 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 53 5.1E-7 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS33030 2ad726877b23a2dbfe273ea6e463d5f7 201 SUPERFAMILY SSF54292 2 79 3.8E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS33030 2ad726877b23a2dbfe273ea6e463d5f7 201 Gene3D G3DSA:3.10.20.30 1 77 2.3E-23 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS33030 2ad726877b23a2dbfe273ea6e463d5f7 201 SUPERFAMILY SSF47741 123 196 3.27E-30 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS33030 2ad726877b23a2dbfe273ea6e463d5f7 201 Pfam PF01799 [2Fe-2S] binding domain 123 190 1.9E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD44_RS33030 2ad726877b23a2dbfe273ea6e463d5f7 201 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Pfam PF00562 RNA polymerase Rpb2, domain 6 630 1047 2.9E-155 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Gene3D G3DSA:2.40.50.100 626 697 2.3E-23 T 28-03-2018 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1125 12.316 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Gene3D G3DSA:3.90.1110.10 166 329 1.7E-71 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Gene3D G3DSA:3.90.1800.10 1050 1094 1.6E-11 T 28-03-2018 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 SUPERFAMILY SSF64484 22 1133 0.0 T 28-03-2018 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Gene3D G3DSA:3.90.1100.10 330 557 3.6E-80 T 28-03-2018 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Gene3D G3DSA:3.90.1100.10 558 625 5.1E-14 T 28-03-2018 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Gene3D G3DSA:2.40.270.10 698 800 7.0E-10 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Gene3D G3DSA:2.40.270.10 826 933 3.1E-49 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Gene3D G3DSA:2.40.270.10 934 1025 1.6E-17 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 4.1E-27 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Pfam PF04563 RNA polymerase beta subunit 37 409 1.1E-20 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Pfam PF10385 RNA polymerase beta subunit external 1 domain 502 568 2.2E-24 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 236 842 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 365 6.3E-30 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS25460 f3652cc0f25aed5b1b95cc638901c045 1161 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 492 1.3E-28 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 SUPERFAMILY SSF56112 324 355 5.93E-75 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 SUPERFAMILY SSF56112 7 278 5.93E-75 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 ProSitePatterns PS00546 Matrixins cysteine switch. 391 398 - T 28-03-2018 IPR021158 Peptidase M10A, cysteine switch, zinc binding site GO:0004222|GO:0006508|GO:0008270|GO:0031012 Reactome: R-HSA-1442490|Reactome: R-HSA-1474228|Reactome: R-HSA-1592389 SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 Gene3D G3DSA:3.30.200.20 2 112 6.4E-22 T 28-03-2018 SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 Pfam PF00069 Protein kinase domain 10 270 1.6E-48 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 Gene3D G3DSA:1.10.510.10 113 306 3.7E-49 T 28-03-2018 SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 SMART SM00220 10 283 3.8E-65 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS40010 f2cb2b0a26d7a21588ad6b6915719be4 428 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS29155 761cce3fbf2f5042e4cf6b2dbbf80dc7 276 SUPERFAMILY SSF47413 15 69 1.05E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS29155 761cce3fbf2f5042e4cf6b2dbbf80dc7 276 SMART SM00530 20 75 2.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS29155 761cce3fbf2f5042e4cf6b2dbbf80dc7 276 Pfam PF13560 Helix-turn-helix domain 16 75 7.3E-15 T 28-03-2018 SMD44_RS29155 761cce3fbf2f5042e4cf6b2dbbf80dc7 276 Gene3D G3DSA:1.10.260.40 2 103 2.9E-17 T 28-03-2018 SMD44_RS16990 c9b16acf57c1d0fa028546618694bb89 165 Gene3D G3DSA:1.10.10.10 1 163 2.0E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16990 c9b16acf57c1d0fa028546618694bb89 165 Pfam PF01047 MarR family 54 111 8.5E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS16990 c9b16acf57c1d0fa028546618694bb89 165 SMART SM00347 43 146 4.0E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS16990 c9b16acf57c1d0fa028546618694bb89 165 SUPERFAMILY SSF46785 11 160 2.22E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16990 c9b16acf57c1d0fa028546618694bb89 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 1.6E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS16990 c9b16acf57c1d0fa028546618694bb89 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 1.6E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS16990 c9b16acf57c1d0fa028546618694bb89 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 1.6E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS16990 c9b16acf57c1d0fa028546618694bb89 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 1.6E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS07950 425becac0a921f894a9f442fc32c61fc 400 Gene3D G3DSA:3.20.20.10 27 280 2.8E-42 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS07950 425becac0a921f894a9f442fc32c61fc 400 SUPERFAMILY SSF51419 26 272 8.34E-21 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS07950 425becac0a921f894a9f442fc32c61fc 400 Pfam PF01168 Alanine racemase, N-terminal domain 25 273 2.6E-16 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS02230 be7bf7f24b2cedc72e06ecc611265762 415 PRINTS PR00758 Arsenical pump membrane protein signature 104 128 1.7E-13 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SMD44_RS02230 be7bf7f24b2cedc72e06ecc611265762 415 PRINTS PR00758 Arsenical pump membrane protein signature 349 374 1.7E-13 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SMD44_RS02230 be7bf7f24b2cedc72e06ecc611265762 415 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 1.7E-13 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SMD44_RS02230 be7bf7f24b2cedc72e06ecc611265762 415 Pfam PF02040 Arsenical pump membrane protein 8 406 2.3E-21 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SMD44_RS16555 d3d684a523a8ff5b9355ea9d658f88dc 183 Pfam PF04138 GtrA-like protein 20 140 2.7E-23 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 Gene3D G3DSA:3.40.50.1100 82 210 5.8E-41 T 28-03-2018 SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 Gene3D G3DSA:3.40.50.1100 21 81 1.6E-7 T 28-03-2018 SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 SUPERFAMILY SSF53686 15 402 1.57E-146 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 Gene3D G3DSA:3.40.50.1100 211 414 3.1E-43 T 28-03-2018 SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 2.6E-184 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 390 6.6E-51 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 PIRSF PIRSF001413 8 407 1.3E-158 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD44_RS10770 901a2ba1d0a3f5c9e643ff66d9337600 431 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 51.388 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 258 3.2E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 SMART SM00304 141 200 8.5E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 SMART SM00388 201 259 5.7E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 405 4.4E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 Gene3D G3DSA:3.30.565.10 243 405 2.6E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 SMART SM00387 304 406 2.1E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 Pfam PF00672 HAMP domain 142 197 2.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 SUPERFAMILY SSF47384 184 258 4.12E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 Gene3D G3DSA:1.10.287.130 191 242 3.3E-11 T 28-03-2018 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 SUPERFAMILY SSF55874 248 404 1.11E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 404 6.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 349 6.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS13380 9163d6a38f1e4f6276f5cb11ce805a21 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 385 6.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 SMART SM00358 176 242 2.9E-23 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 SUPERFAMILY SSF69065 20 178 4.36E-49 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 Gene3D G3DSA:3.30.160.20 164 238 9.7E-22 T 28-03-2018 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 SMART SM00535 36 169 3.4E-62 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 Pfam PF14622 Ribonuclease-III-like 35 160 2.4E-38 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 Hamap MF_00104 Ribonuclease 3 [rnc]. 25 238 30.56 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 Pfam PF00035 Double-stranded RNA binding motif 176 239 8.0E-17 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 SUPERFAMILY SSF54768 130 241 2.99E-26 T 28-03-2018 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 ProSitePatterns PS00517 Ribonuclease III family signature. 58 66 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 Gene3D G3DSA:1.10.1520.10 8 163 1.6E-44 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD44_RS30360 033edc31591b024567d7935b34a143e5 272 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 27 240 4.2E-73 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SMD44_RS18335 82310501c927249ddc3e5330f4734c2f 283 PIRSF PIRSF006648 14 283 1.6E-66 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS18335 82310501c927249ddc3e5330f4734c2f 283 Pfam PF01061 ABC-2 type transporter 33 238 1.8E-27 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 SMART SM00448 6 119 9.0E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 Pfam PF00072 Response regulator receiver domain 9 119 7.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 6.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 6.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 6.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 SUPERFAMILY SSF46894 137 209 6.46E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 SUPERFAMILY SSF52172 6 138 1.05E-33 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 1.0E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 SMART SM00421 146 203 2.0E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 Gene3D G3DSA:3.40.50.2300 5 130 1.2E-34 T 28-03-2018 SMD44_RS29540 ffd8f095067d4ddd69fdfe4af78c6ad9 210 Gene3D G3DSA:1.10.10.10 131 210 3.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 26 170 28.559 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 Pfam PF12838 4Fe-4S dicluster domain 78 138 6.9E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 Gene3D G3DSA:3.30.70.20 90 130 5.8E-16 T 28-03-2018 SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 79 90 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 124 135 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 Gene3D G3DSA:3.30.70.20 51 89 1.3E-6 T 28-03-2018 SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 Gene3D G3DSA:3.30.70.20 131 161 2.4E-6 T 28-03-2018 SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 SUPERFAMILY SSF54862 52 168 8.79E-27 T 28-03-2018 SMD44_RS25060 a57b90b9b2272f3dc4cb1254e2092058 236 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 35 162 4.1E-44 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS27785 ffa90705ba442652123a1e37a0d02652 282 Pfam PF13371 Tetratricopeptide repeat 200 273 1.0E-12 T 28-03-2018 SMD44_RS27785 ffa90705ba442652123a1e37a0d02652 282 Pfam PF13369 Transglutaminase-like superfamily 48 198 1.7E-38 T 28-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 Gene3D G3DSA:3.30.450.20 146 268 7.8E-17 T 28-03-2018 SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 Pfam PF08448 PAS fold 154 270 3.0E-9 T 28-03-2018 IPR013656 PAS fold-4 SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 Gene3D G3DSA:3.30.450.40 269 451 2.1E-17 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 145 8.1E-14 T 28-03-2018 IPR000014 PAS domain SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 Gene3D G3DSA:3.30.450.20 22 145 2.9E-22 T 28-03-2018 SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 Pfam PF00989 PAS fold 25 135 8.9E-13 T 28-03-2018 IPR013767 PAS fold GO:0006355 SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 SUPERFAMILY SSF55785 24 132 2.44E-20 T 28-03-2018 IPR000014 PAS domain SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 SUPERFAMILY SSF55781 315 450 5.49E-6 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 SUPERFAMILY SSF55785 139 225 1.95E-10 T 28-03-2018 IPR000014 PAS domain SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 SMART SM00091 24 92 9.0E-7 T 28-03-2018 IPR000014 PAS domain SMD44_RS18175 9badc4580248f42e099cfd63634d1b99 454 SMART SM00091 148 213 0.022 T 28-03-2018 IPR000014 PAS domain SMD44_RS15750 c687da4ffd2bed3f3beb4e889e80d3d9 381 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 22 381 2.9E-134 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 SMD44_RS15750 c687da4ffd2bed3f3beb4e889e80d3d9 381 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 185 335 7.0E-17 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS15750 c687da4ffd2bed3f3beb4e889e80d3d9 381 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 22 136 9.7E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS15750 c687da4ffd2bed3f3beb4e889e80d3d9 381 Gene3D G3DSA:3.10.180.10 5 176 7.0E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS15750 c687da4ffd2bed3f3beb4e889e80d3d9 381 SUPERFAMILY SSF54593 15 368 3.42E-92 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS15750 c687da4ffd2bed3f3beb4e889e80d3d9 381 Gene3D G3DSA:3.10.180.10 180 381 2.8E-69 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS15750 c687da4ffd2bed3f3beb4e889e80d3d9 381 PIRSF PIRSF009283 8 381 2.1E-134 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 SMD44_RS39025 5d2eb54284992e31683b2bf67050904f 151 Gene3D G3DSA:2.60.120.10 4 141 6.3E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS39025 5d2eb54284992e31683b2bf67050904f 151 Pfam PF00027 Cyclic nucleotide-binding domain 26 111 3.7E-7 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS39025 5d2eb54284992e31683b2bf67050904f 151 SUPERFAMILY SSF51206 7 142 1.44E-17 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 14 309 4.6E-83 T 28-03-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 Gene3D G3DSA:3.30.9.10 167 319 5.1E-27 T 28-03-2018 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 SUPERFAMILY SSF51905 271 359 2.47E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 SUPERFAMILY SSF51905 14 182 2.47E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 Pfam PF01494 FAD binding domain 101 295 3.5E-7 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 Gene3D G3DSA:3.50.50.60 7 166 4.4E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 Pfam PF00890 FAD binding domain 15 81 2.9E-8 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 1.3E-12 T 28-03-2018 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 15 37 1.3E-12 T 28-03-2018 SMD44_RS04135 676c78e0b4320dde0965d27870ddb962 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 1.3E-12 T 28-03-2018 SMD44_RS04985 0b3fd768f06411e0305ae7216d88d77f 243 Pfam PF13309 HTH domain 164 222 2.1E-17 T 28-03-2018 SMD44_RS04985 0b3fd768f06411e0305ae7216d88d77f 243 Pfam PF08348 YheO-like PAS domain 23 130 5.8E-34 T 28-03-2018 IPR013559 YheO-like SMD44_RS04985 0b3fd768f06411e0305ae7216d88d77f 243 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 27 135 2.0E-40 T 28-03-2018 IPR013559 YheO-like SMD44_RS04985 0b3fd768f06411e0305ae7216d88d77f 243 Gene3D G3DSA:1.10.10.60 170 231 1.4E-5 T 28-03-2018 SMD44_RS18220 607fdbd203921ea8f51499c9e336fce0 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 1.2E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS18220 607fdbd203921ea8f51499c9e336fce0 222 Gene3D G3DSA:1.10.10.10 119 220 5.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18220 607fdbd203921ea8f51499c9e336fce0 222 SMART SM00448 1 112 4.8E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18220 607fdbd203921ea8f51499c9e336fce0 222 Pfam PF00072 Response regulator receiver domain 3 112 5.5E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS18220 607fdbd203921ea8f51499c9e336fce0 222 SUPERFAMILY SSF52172 1 174 4.55E-33 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS18220 607fdbd203921ea8f51499c9e336fce0 222 Gene3D G3DSA:3.40.50.2300 1 118 3.4E-28 T 28-03-2018 SMD44_RS18220 607fdbd203921ea8f51499c9e336fce0 222 SMART SM00862 145 217 1.4E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS15985 6b29fb027f05240e2e181aff90db4953 206 Pfam PF08044 Domain of unknown function (DUF1707) 21 72 6.6E-18 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 SMD44_RS35005 8e9c2a07f9653fcad9436dfee8891852 738 SUPERFAMILY SSF48576 380 713 2.42E-66 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS35005 8e9c2a07f9653fcad9436dfee8891852 738 Gene3D G3DSA:1.10.600.10 3 341 9.9E-84 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS35005 8e9c2a07f9653fcad9436dfee8891852 738 SUPERFAMILY SSF48576 7 334 2.88E-69 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS35005 8e9c2a07f9653fcad9436dfee8891852 738 Gene3D G3DSA:1.10.600.10 381 714 2.3E-78 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS01520 05ad8bf550376f30262d15b18c608947 330 SUPERFAMILY SSF47413 2 54 1.02E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS01520 05ad8bf550376f30262d15b18c608947 330 Gene3D G3DSA:3.40.50.2300 52 172 5.8E-21 T 28-03-2018 SMD44_RS01520 05ad8bf550376f30262d15b18c608947 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 45 2.4E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS01520 05ad8bf550376f30262d15b18c608947 330 Gene3D G3DSA:1.10.260.40 1 51 2.8E-22 T 28-03-2018 SMD44_RS01520 05ad8bf550376f30262d15b18c608947 330 Pfam PF13377 Periplasmic binding protein-like domain 165 323 2.2E-36 T 28-03-2018 SMD44_RS01520 05ad8bf550376f30262d15b18c608947 330 Gene3D G3DSA:3.40.50.2300 173 327 2.5E-46 T 28-03-2018 SMD44_RS01520 05ad8bf550376f30262d15b18c608947 330 SMART SM00354 1 68 1.1E-23 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS01520 05ad8bf550376f30262d15b18c608947 330 SUPERFAMILY SSF53822 57 326 2.94E-54 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS31445 dfa05bf793ceab19f020912448bd4250 273 Pfam PF00797 N-acetyltransferase 26 259 3.3E-65 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS31445 dfa05bf793ceab19f020912448bd4250 273 Gene3D G3DSA:3.30.2140.10 4 155 2.2E-45 T 28-03-2018 SMD44_RS31445 dfa05bf793ceab19f020912448bd4250 273 Gene3D G3DSA:3.30.2140.10 156 271 4.3E-17 T 28-03-2018 SMD44_RS31445 dfa05bf793ceab19f020912448bd4250 273 PRINTS PR01543 Arylamine N-acetyltransferase signature 50 73 1.2E-12 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS31445 dfa05bf793ceab19f020912448bd4250 273 PRINTS PR01543 Arylamine N-acetyltransferase signature 26 49 1.2E-12 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS31445 dfa05bf793ceab19f020912448bd4250 273 PRINTS PR01543 Arylamine N-acetyltransferase signature 74 96 1.2E-12 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS31445 dfa05bf793ceab19f020912448bd4250 273 PRINTS PR01543 Arylamine N-acetyltransferase signature 133 153 1.2E-12 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS31445 dfa05bf793ceab19f020912448bd4250 273 SUPERFAMILY SSF54001 7 265 3.73E-76 T 28-03-2018 SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 201 4.6E-4 T 28-03-2018 SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 Gene3D G3DSA:3.40.50.720 2 228 3.4E-52 T 28-03-2018 SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 SUPERFAMILY SSF51735 3 216 1.69E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29800 f9f47841008cf0806c7ecbf1b163fa92 229 Pfam PF00106 short chain dehydrogenase 5 189 2.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS03475 af25a4817e0deae100efd77ea716341d 411 SUPERFAMILY SSF51905 271 359 3.68E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03475 af25a4817e0deae100efd77ea716341d 411 SUPERFAMILY SSF51905 5 177 3.68E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03475 af25a4817e0deae100efd77ea716341d 411 Gene3D G3DSA:3.50.50.60 2 321 1.4E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03475 af25a4817e0deae100efd77ea716341d 411 Pfam PF01494 FAD binding domain 4 329 1.2E-55 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS03475 af25a4817e0deae100efd77ea716341d 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 1.4E-20 T 28-03-2018 SMD44_RS03475 af25a4817e0deae100efd77ea716341d 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.4E-20 T 28-03-2018 SMD44_RS03475 af25a4817e0deae100efd77ea716341d 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.4E-20 T 28-03-2018 SMD44_RS03475 af25a4817e0deae100efd77ea716341d 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 1.4E-20 T 28-03-2018 SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 SUPERFAMILY SSF52467 212 387 2.7E-62 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 31 196 1.1E-54 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 SUPERFAMILY SSF52518 396 608 6.08E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 456 475 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 Gene3D G3DSA:3.40.50.1220 225 379 2.1E-57 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 Gene3D G3DSA:3.40.50.970 380 602 2.2E-54 T 28-03-2018 SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 Gene3D G3DSA:3.40.50.970 24 224 2.9E-58 T 28-03-2018 SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 355 1.8E-47 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 SUPERFAMILY SSF52518 29 209 1.22E-59 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 419 582 1.1E-48 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD44_RS29910 78ade39c60e498588703feffa0572a4a 619 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 31 605 1.4E-232 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMD44_RS14105 2afdfed34115eea6317e666ff21cac72 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 3.0E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS14105 2afdfed34115eea6317e666ff21cac72 231 Pfam PF00072 Response regulator receiver domain 5 112 2.6E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS14105 2afdfed34115eea6317e666ff21cac72 231 SMART SM00448 2 112 2.2E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS14105 2afdfed34115eea6317e666ff21cac72 231 Gene3D G3DSA:3.40.50.2300 1 124 1.0E-33 T 28-03-2018 SMD44_RS14105 2afdfed34115eea6317e666ff21cac72 231 SUPERFAMILY SSF52172 3 176 6.26E-38 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS14105 2afdfed34115eea6317e666ff21cac72 231 Gene3D G3DSA:1.10.10.10 125 225 4.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14105 2afdfed34115eea6317e666ff21cac72 231 SMART SM00862 146 221 2.5E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS03390 cb9af1e721175a5f2942dfef6c7c410b 388 SUPERFAMILY SSF53901 6 122 3.29E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS03390 cb9af1e721175a5f2942dfef6c7c410b 388 SUPERFAMILY SSF53901 182 378 3.29E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS03390 cb9af1e721175a5f2942dfef6c7c410b 388 Gene3D G3DSA:3.40.47.10 147 376 5.5E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS03390 cb9af1e721175a5f2942dfef6c7c410b 388 PIRSF PIRSF000429 2 377 2.6E-16 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS03390 cb9af1e721175a5f2942dfef6c7c410b 388 Gene3D G3DSA:3.30.420.40 6 146 4.1E-5 T 28-03-2018 SMD44_RS13365 1bf9565a2a59d596716c7d813294e910 142 SUPERFAMILY SSF54913 34 137 7.41E-34 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMD44_RS13365 1bf9565a2a59d596716c7d813294e910 142 Pfam PF03091 CutA1 divalent ion tolerance protein 38 134 1.2E-32 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 SMD44_RS13365 1bf9565a2a59d596716c7d813294e910 142 Gene3D G3DSA:3.30.70.120 34 140 6.0E-35 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMD44_RS19065 92c4ce207a7fcf389cd0c8b41f2e694a 577 SUPERFAMILY SSF51126 71 301 2.24E-20 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS19065 92c4ce207a7fcf389cd0c8b41f2e694a 577 SUPERFAMILY SSF51126 338 487 2.24E-20 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS19065 92c4ce207a7fcf389cd0c8b41f2e694a 577 Pfam PF12708 Pectate lyase superfamily protein 80 163 1.7E-10 T 28-03-2018 IPR024535 Pectate lyase superfamily protein SMD44_RS19065 92c4ce207a7fcf389cd0c8b41f2e694a 577 Gene3D G3DSA:2.160.20.10 61 511 1.4E-26 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS27790 9cfe463617b8fd2a3ef2217208f55267 284 Pfam PF13369 Transglutaminase-like superfamily 49 200 9.6E-43 T 28-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMD44_RS27790 9cfe463617b8fd2a3ef2217208f55267 284 Pfam PF13371 Tetratricopeptide repeat 202 273 7.9E-12 T 28-03-2018 SMD44_RS22310 d6db77cdd4e24a1774a32ad2c97d0ce2 422 Gene3D G3DSA:1.10.10.60 349 393 1.2E-5 T 28-03-2018 SMD44_RS22310 d6db77cdd4e24a1774a32ad2c97d0ce2 422 Pfam PF13556 PucR C-terminal helix-turn-helix domain 357 403 1.9E-14 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS16470 5c11b3485280085b01228d7ca5578e4f 404 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 97 252 2.7E-48 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS16470 5c11b3485280085b01228d7ca5578e4f 404 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 97 252 7.6E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS24100 0070988ad3ec97c14cb22bf9b51fa575 80 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 24 71 2.2E-20 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD44_RS24100 0070988ad3ec97c14cb22bf9b51fa575 80 Gene3D G3DSA:1.10.1660.20 35 67 7.1E-12 T 28-03-2018 SMD44_RS24100 0070988ad3ec97c14cb22bf9b51fa575 80 Gene3D G3DSA:1.10.10.60 12 34 0.0011 T 28-03-2018 SMD44_RS24100 0070988ad3ec97c14cb22bf9b51fa575 80 SUPERFAMILY SSF46955 24 72 6.23E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS24100 0070988ad3ec97c14cb22bf9b51fa575 80 Pfam PF12728 Helix-turn-helix domain 24 71 2.1E-14 T 28-03-2018 SMD44_RS21080 b89629b17696d0c0b9f8966a6533560b 370 Gene3D G3DSA:3.90.1530.10 73 176 5.3E-38 T 28-03-2018 SMD44_RS21080 b89629b17696d0c0b9f8966a6533560b 370 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 84 261 1.6E-60 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 SMD44_RS21080 b89629b17696d0c0b9f8966a6533560b 370 Gene3D G3DSA:1.10.10.730 177 224 9.4E-18 T 28-03-2018 SMD44_RS21080 b89629b17696d0c0b9f8966a6533560b 370 SUPERFAMILY SSF109709 168 277 1.12E-32 T 28-03-2018 SMD44_RS21080 b89629b17696d0c0b9f8966a6533560b 370 Pfam PF02195 ParB-like nuclease domain 87 175 1.0E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS21080 b89629b17696d0c0b9f8966a6533560b 370 SMART SM00470 86 176 1.6E-36 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS21080 b89629b17696d0c0b9f8966a6533560b 370 SUPERFAMILY SSF110849 72 179 7.32E-29 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS00700 c2d36a72896306ce0959eef41060ab7d 246 Gene3D G3DSA:3.40.50.150 3 224 1.4E-34 T 28-03-2018 SMD44_RS00700 c2d36a72896306ce0959eef41060ab7d 246 Pfam PF08241 Methyltransferase domain 55 148 1.3E-19 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS00700 c2d36a72896306ce0959eef41060ab7d 246 SUPERFAMILY SSF53335 8 226 3.84E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS42730 6844629a9c9650abdccc9de514df869c 257 Hamap MF_00165 Thymidylate kinase [tmk]. 13 228 13.898 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMD44_RS42730 6844629a9c9650abdccc9de514df869c 257 Pfam PF02223 Thymidylate kinase 18 207 6.3E-11 T 28-03-2018 SMD44_RS42730 6844629a9c9650abdccc9de514df869c 257 Gene3D G3DSA:3.40.50.300 10 233 1.1E-18 T 28-03-2018 SMD44_RS42730 6844629a9c9650abdccc9de514df869c 257 SUPERFAMILY SSF52540 11 226 1.9E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07730 18ef88719fc9385015111f17c071e57b 514 SUPERFAMILY SSF103473 14 206 9.16E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS07730 18ef88719fc9385015111f17c071e57b 514 SUPERFAMILY SSF103473 256 427 9.16E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS07730 18ef88719fc9385015111f17c071e57b 514 SUPERFAMILY SSF103473 478 504 9.16E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS07730 18ef88719fc9385015111f17c071e57b 514 Gene3D G3DSA:1.20.1250.20 267 509 5.8E-26 T 28-03-2018 SMD44_RS07730 18ef88719fc9385015111f17c071e57b 514 Gene3D G3DSA:1.20.1250.20 16 209 3.3E-32 T 28-03-2018 SMD44_RS07730 18ef88719fc9385015111f17c071e57b 514 Pfam PF07690 Major Facilitator Superfamily 26 417 8.4E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS11120 f90a45768dc65999191d240b15de93b9 205 SUPERFAMILY SSF48498 90 197 4.7E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS11120 f90a45768dc65999191d240b15de93b9 205 Gene3D G3DSA:1.10.10.60 2 61 8.1E-21 T 28-03-2018 SMD44_RS11120 f90a45768dc65999191d240b15de93b9 205 Gene3D G3DSA:1.10.357.10 62 198 6.3E-22 T 28-03-2018 SMD44_RS11120 f90a45768dc65999191d240b15de93b9 205 SUPERFAMILY SSF46689 8 82 4.46E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS11120 f90a45768dc65999191d240b15de93b9 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 3.7E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11120 f90a45768dc65999191d240b15de93b9 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11120 f90a45768dc65999191d240b15de93b9 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS13425 e04e7332c75ff50120f2b08e51916eba 123 Gene3D G3DSA:2.102.10.10 16 122 1.4E-16 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS13425 e04e7332c75ff50120f2b08e51916eba 123 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 24 121 2.3E-26 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 SMD44_RS13425 e04e7332c75ff50120f2b08e51916eba 123 Pfam PF13806 Rieske-like [2Fe-2S] domain 24 121 1.5E-30 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 SMD44_RS13425 e04e7332c75ff50120f2b08e51916eba 123 SUPERFAMILY SSF50022 24 121 2.51E-28 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS03920 887aab4af65325128863a103cff8283c 397 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 1 395 44.389 T 28-03-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS03920 887aab4af65325128863a103cff8283c 397 Pfam PF05175 Methyltransferase small domain 219 392 3.2E-55 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMD44_RS03920 887aab4af65325128863a103cff8283c 397 Gene3D G3DSA:3.40.50.150 213 397 5.3E-31 T 28-03-2018 SMD44_RS03920 887aab4af65325128863a103cff8283c 397 PIRSF PIRSF037565 1 396 1.2E-128 T 28-03-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD44_RS03920 887aab4af65325128863a103cff8283c 397 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 324 330 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD44_RS03920 887aab4af65325128863a103cff8283c 397 SUPERFAMILY SSF53335 231 370 1.66E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS03920 887aab4af65325128863a103cff8283c 397 Gene3D G3DSA:3.40.50.720 59 198 0.11 T 28-03-2018 SMD44_RS08110 462721bf3d88edb96639b3f333d422ae 338 Pfam PF13280 WYL domain 169 335 7.3E-32 T 28-03-2018 IPR026881 WYL domain SMD44_RS21220 e10734720cd96b9170fb380d4099eda6 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21220 e10734720cd96b9170fb380d4099eda6 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21220 e10734720cd96b9170fb380d4099eda6 209 SUPERFAMILY SSF46689 4 81 3.95E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS21220 e10734720cd96b9170fb380d4099eda6 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 6.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21220 e10734720cd96b9170fb380d4099eda6 209 Gene3D G3DSA:1.10.10.60 2 64 2.2E-16 T 28-03-2018 SMD44_RS21220 e10734720cd96b9170fb380d4099eda6 209 Gene3D G3DSA:1.10.357.10 65 204 1.2E-15 T 28-03-2018 SMD44_RS00060 37dfc1ca8f03468e2f3f39986f24d4a2 181 Gene3D G3DSA:3.40.50.300 7 178 1.1E-23 T 28-03-2018 SMD44_RS00060 37dfc1ca8f03468e2f3f39986f24d4a2 181 PRINTS PR01100 Shikimate kinase family signature 110 127 1.2E-6 T 28-03-2018 SMD44_RS00060 37dfc1ca8f03468e2f3f39986f24d4a2 181 PRINTS PR01100 Shikimate kinase family signature 12 27 1.2E-6 T 28-03-2018 SMD44_RS00060 37dfc1ca8f03468e2f3f39986f24d4a2 181 Pfam PF13671 AAA domain 12 155 3.1E-23 T 28-03-2018 SMD44_RS00060 37dfc1ca8f03468e2f3f39986f24d4a2 181 SUPERFAMILY SSF52540 10 163 3.82E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS26375 18a199ab42719c731e2f84982581669d 469 SUPERFAMILY SSF52777 32 231 2.33E-19 T 28-03-2018 SMD44_RS26375 18a199ab42719c731e2f84982581669d 469 SUPERFAMILY SSF52777 237 451 9.34E-15 T 28-03-2018 SMD44_RS26375 18a199ab42719c731e2f84982581669d 469 Gene3D G3DSA:3.30.559.10 20 222 1.4E-13 T 28-03-2018 SMD44_RS26375 18a199ab42719c731e2f84982581669d 469 Pfam PF00668 Condensation domain 64 370 5.0E-22 T 28-03-2018 IPR001242 Condensation domain SMD44_RS30165 13fc1fd195f4c223ddd7f71aeac63d04 137 Pfam PF03259 Roadblock/LC7 domain 9 99 6.9E-26 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS30165 13fc1fd195f4c223ddd7f71aeac63d04 137 SMART SM00960 9 99 2.0E-33 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS30165 13fc1fd195f4c223ddd7f71aeac63d04 137 Gene3D G3DSA:3.30.450.30 4 131 4.2E-44 T 28-03-2018 SMD44_RS30165 13fc1fd195f4c223ddd7f71aeac63d04 137 SUPERFAMILY SSF103196 2 125 5.89E-32 T 28-03-2018 SMD44_RS41175 c8ec0bb8dd6a85619cc4f2bdd531c6b9 86 Pfam PF00550 Phosphopantetheine attachment site 13 73 1.4E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS41175 c8ec0bb8dd6a85619cc4f2bdd531c6b9 86 SUPERFAMILY SSF47336 11 84 4.97E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS41175 c8ec0bb8dd6a85619cc4f2bdd531c6b9 86 Gene3D G3DSA:1.10.1200.10 11 86 2.7E-15 T 28-03-2018 SMD44_RS31275 9385d54fec68e3a9e6893d010852a86e 229 Gene3D G3DSA:1.10.10.10 129 229 2.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31275 9385d54fec68e3a9e6893d010852a86e 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 224 8.8E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS31275 9385d54fec68e3a9e6893d010852a86e 229 SUPERFAMILY SSF52172 1 186 1.57E-37 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS31275 9385d54fec68e3a9e6893d010852a86e 229 Gene3D G3DSA:3.40.50.2300 1 128 7.0E-36 T 28-03-2018 SMD44_RS31275 9385d54fec68e3a9e6893d010852a86e 229 SMART SM00448 1 114 4.5E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31275 9385d54fec68e3a9e6893d010852a86e 229 Pfam PF00072 Response regulator receiver domain 4 114 4.0E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31275 9385d54fec68e3a9e6893d010852a86e 229 SMART SM00862 152 224 1.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS24045 3a6fbf3e6fa3332fa1593677448c189f 194 Pfam PF00857 Isochorismatase family 8 153 8.5E-29 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS24045 3a6fbf3e6fa3332fa1593677448c189f 194 Gene3D G3DSA:3.40.50.850 3 193 1.8E-38 T 28-03-2018 SMD44_RS24045 3a6fbf3e6fa3332fa1593677448c189f 194 SUPERFAMILY SSF52499 4 190 1.01E-40 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS13100 652aabf56af904a0fe702cc4a591314a 277 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 98 268 1.1E-15 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 SMD44_RS13100 652aabf56af904a0fe702cc4a591314a 277 Pfam PF08798 CRISPR associated protein 3 268 1.3E-59 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 SMD44_RS13100 652aabf56af904a0fe702cc4a591314a 277 Gene3D G3DSA:3.30.70.1210 95 268 3.1E-32 T 28-03-2018 SMD44_RS13100 652aabf56af904a0fe702cc4a591314a 277 Gene3D G3DSA:3.30.70.1200 1 85 2.1E-22 T 28-03-2018 SMD44_RS13100 652aabf56af904a0fe702cc4a591314a 277 SUPERFAMILY SSF117987 3 80 5.75E-20 T 28-03-2018 SMD44_RS13100 652aabf56af904a0fe702cc4a591314a 277 SUPERFAMILY SSF117987 209 268 7.06E-26 T 28-03-2018 SMD44_RS13100 652aabf56af904a0fe702cc4a591314a 277 SUPERFAMILY SSF117987 96 179 7.06E-26 T 28-03-2018 SMD44_RS13100 652aabf56af904a0fe702cc4a591314a 277 SMART SM01101 2 268 1.5E-60 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 SMD44_RS36255 99aeb5eb3038369d2cbc36b09cffd40e 125 Gene3D G3DSA:3.30.70.100 7 115 5.9E-5 T 28-03-2018 SMD44_RS36255 99aeb5eb3038369d2cbc36b09cffd40e 125 Pfam PF11639 REDY-like protein HapK 22 124 3.1E-42 T 28-03-2018 IPR021667 REDY-like protein HapK SMD44_RS20515 a0bcd465eb870e7e5b46939937ff3923 252 Gene3D G3DSA:1.10.10.10 2 74 3.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20515 a0bcd465eb870e7e5b46939937ff3923 252 Pfam PF07702 UTRA domain 105 235 9.7E-18 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS20515 a0bcd465eb870e7e5b46939937ff3923 252 SMART SM00866 98 244 7.8E-9 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS20515 a0bcd465eb870e7e5b46939937ff3923 252 SUPERFAMILY SSF64288 61 237 1.54E-21 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS20515 a0bcd465eb870e7e5b46939937ff3923 252 SUPERFAMILY SSF46785 3 77 1.57E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20515 a0bcd465eb870e7e5b46939937ff3923 252 Gene3D G3DSA:3.40.1410.10 77 243 6.3E-25 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS20515 a0bcd465eb870e7e5b46939937ff3923 252 SMART SM00345 14 73 1.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS20515 a0bcd465eb870e7e5b46939937ff3923 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 3.5E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS09975 337569738e39271847253c5629279ad3 185 SUPERFAMILY SSF48498 98 177 1.02E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS09975 337569738e39271847253c5629279ad3 185 SUPERFAMILY SSF46689 5 73 1.8E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS09975 337569738e39271847253c5629279ad3 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS09975 337569738e39271847253c5629279ad3 185 Gene3D G3DSA:1.10.357.10 7 184 1.6E-36 T 28-03-2018 SMD44_RS17840 4c04e90099f8ffba3f97024a9af0cf79 214 Gene3D G3DSA:3.40.50.720 1 210 4.1E-31 T 28-03-2018 SMD44_RS17840 4c04e90099f8ffba3f97024a9af0cf79 214 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 2.5E-15 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMD44_RS17840 4c04e90099f8ffba3f97024a9af0cf79 214 SUPERFAMILY SSF51735 1 200 2.4E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS42000 b2c91a879e738c2973136a37bb794292 201 SUPERFAMILY SSF53474 3 141 1.37E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS42000 b2c91a879e738c2973136a37bb794292 201 Pfam PF00561 alpha/beta hydrolase fold 5 88 4.2E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS42000 b2c91a879e738c2973136a37bb794292 201 Gene3D G3DSA:3.40.50.1820 2 187 6.6E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS00770 8f1b0eae78be720ec26d6dd8fc59465a 259 Gene3D G3DSA:3.40.50.1820 1 259 3.9E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS00770 8f1b0eae78be720ec26d6dd8fc59465a 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.2E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS00770 8f1b0eae78be720ec26d6dd8fc59465a 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 2.2E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS00770 8f1b0eae78be720ec26d6dd8fc59465a 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 2.2E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS00770 8f1b0eae78be720ec26d6dd8fc59465a 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 2.2E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS00770 8f1b0eae78be720ec26d6dd8fc59465a 259 Pfam PF12697 Alpha/beta hydrolase family 28 248 8.9E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS00770 8f1b0eae78be720ec26d6dd8fc59465a 259 SUPERFAMILY SSF53474 5 253 9.73E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01350 b8afcae1b28fa6b21437180183142829 394 SUPERFAMILY SSF56601 39 383 1.08E-63 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS01350 b8afcae1b28fa6b21437180183142829 394 Pfam PF00144 Beta-lactamase 50 383 1.9E-56 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS01350 b8afcae1b28fa6b21437180183142829 394 Gene3D G3DSA:3.40.710.10 34 390 1.3E-64 T 28-03-2018 SMD44_RS24190 abe751df43d826703bcb32195372d03d 400 SUPERFAMILY SSF53383 15 398 6.12E-110 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS24190 abe751df43d826703bcb32195372d03d 400 Gene3D G3DSA:3.40.640.10 64 278 3.8E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS24190 abe751df43d826703bcb32195372d03d 400 Pfam PF00155 Aminotransferase class I and II 60 395 2.8E-35 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS24190 abe751df43d826703bcb32195372d03d 400 Gene3D G3DSA:3.90.1150.10 279 400 9.8E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS15670 d82e5655a6496ae497ecd9087909998e 323 Gene3D G3DSA:3.40.50.1980 165 323 1.2E-37 T 28-03-2018 SMD44_RS15670 d82e5655a6496ae497ecd9087909998e 323 SUPERFAMILY SSF53807 37 303 3.6E-47 T 28-03-2018 SMD44_RS15670 d82e5655a6496ae497ecd9087909998e 323 Gene3D G3DSA:3.40.50.1980 33 164 2.9E-31 T 28-03-2018 SMD44_RS15670 d82e5655a6496ae497ecd9087909998e 323 Pfam PF01497 Periplasmic binding protein 61 301 3.6E-32 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 SUPERFAMILY SSF51905 2 150 3.67E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 SUPERFAMILY SSF51905 255 347 3.67E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 Gene3D G3DSA:3.20.20.70 517 703 3.7E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 SUPERFAMILY SSF51395 405 693 5.0E-49 T 28-03-2018 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 Gene3D G3DSA:3.50.50.60 1 380 4.8E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 2.3E-10 T 28-03-2018 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 2.3E-10 T 28-03-2018 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.3E-10 T 28-03-2018 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 2.3E-10 T 28-03-2018 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 409 521 5.2E-10 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 Pfam PF01494 FAD binding domain 133 324 1.1E-10 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS41230 535302c7e949986b562e7dc884c3298f 704 Gene3D G3DSA:3.20.20.70 398 516 2.5E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS21350 40ab8e3915c61ebcba7415ad600d16c7 133 Pfam PF06236 Tyrosinase co-factor MelC1 21 124 9.3E-30 T 28-03-2018 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 SMD44_RS27990 4d6d1e242e9afa0bf95fae8bbb414463 479 Gene3D G3DSA:3.40.390.10 315 466 1.3E-8 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD44_RS27990 4d6d1e242e9afa0bf95fae8bbb414463 479 Pfam PF11350 Protein of unknown function (DUF3152) 297 477 2.9E-60 T 28-03-2018 IPR022603 Domain of unknown function DUF3152 SMD44_RS27990 4d6d1e242e9afa0bf95fae8bbb414463 479 SUPERFAMILY SSF55486 336 461 4.15E-14 T 28-03-2018 SMD44_RS03775 921fc616e853854204c8e9fd4c3ba563 330 Gene3D G3DSA:3.30.1180.20 184 330 6.0E-48 T 28-03-2018 SMD44_RS03775 921fc616e853854204c8e9fd4c3ba563 330 SUPERFAMILY SSF82549 11 329 2.88E-117 T 28-03-2018 SMD44_RS03775 921fc616e853854204c8e9fd4c3ba563 330 Gene3D G3DSA:3.40.50.10440 11 183 9.7E-70 T 28-03-2018 SMD44_RS03775 921fc616e853854204c8e9fd4c3ba563 330 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 325 5.3E-148 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 SMD44_RS03775 921fc616e853854204c8e9fd4c3ba563 330 Pfam PF02733 Dak1 domain 17 324 1.6E-126 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS11920 f5fd84a487ca8c51f80cfbfa852c9c96 268 Gene3D G3DSA:3.40.50.1820 1 263 1.3E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS11920 f5fd84a487ca8c51f80cfbfa852c9c96 268 SUPERFAMILY SSF53474 1 262 1.41E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS11920 f5fd84a487ca8c51f80cfbfa852c9c96 268 Pfam PF12697 Alpha/beta hydrolase family 18 260 1.2E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS03545 f66e3b0f988b669f999eff1f71886ae6 1488 Gene3D G3DSA:3.40.50.300 15 1420 0.0013 T 28-03-2018 SMD44_RS38030 1ddb40641c3d04ee559cf8203633b6d1 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS38030 1ddb40641c3d04ee559cf8203633b6d1 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS38030 1ddb40641c3d04ee559cf8203633b6d1 210 SUPERFAMILY SSF46689 4 79 1.44E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS38030 1ddb40641c3d04ee559cf8203633b6d1 210 Gene3D G3DSA:1.10.260.40 45 190 4.6E-9 T 28-03-2018 SMD44_RS38030 1ddb40641c3d04ee559cf8203633b6d1 210 Gene3D G3DSA:1.10.10.60 1 44 3.8E-16 T 28-03-2018 SMD44_RS38030 1ddb40641c3d04ee559cf8203633b6d1 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 5.1E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS34010 622eccff07f659271d8248e3156fc699 628 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 440 456 7.0E-32 T 28-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD44_RS34010 622eccff07f659271d8248e3156fc699 628 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 483 501 7.0E-32 T 28-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD44_RS34010 622eccff07f659271d8248e3156fc699 628 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 506 521 7.0E-32 T 28-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD44_RS34010 622eccff07f659271d8248e3156fc699 628 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 148 166 7.0E-32 T 28-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD44_RS34010 622eccff07f659271d8248e3156fc699 628 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 422 436 7.0E-32 T 28-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD44_RS34010 622eccff07f659271d8248e3156fc699 628 Pfam PF01752 Collagenase 323 611 7.6E-117 T 28-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD44_RS34010 622eccff07f659271d8248e3156fc699 628 Pfam PF08453 Peptidase family M9 N-terminal 82 263 6.7E-68 T 28-03-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain SMD44_RS43255 a5828073527f556aa335232dbb9c2e90 293 SUPERFAMILY SSF53335 131 268 1.8E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS43255 a5828073527f556aa335232dbb9c2e90 293 Gene3D G3DSA:3.40.50.150 150 280 1.5E-8 T 28-03-2018 SMD44_RS43255 a5828073527f556aa335232dbb9c2e90 293 Pfam PF02384 N-6 DNA Methylase 161 268 3.8E-5 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMD44_RS29670 d32b22d08d6639b4dd41e072dd20ce0d 230 SUPERFAMILY SSF52540 64 184 2.87E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29670 d32b22d08d6639b4dd41e072dd20ce0d 230 Pfam PF13671 AAA domain 64 180 5.8E-10 T 28-03-2018 SMD44_RS29670 d32b22d08d6639b4dd41e072dd20ce0d 230 Gene3D G3DSA:3.40.50.300 42 74 0.0049 T 28-03-2018 SMD44_RS29670 d32b22d08d6639b4dd41e072dd20ce0d 230 Gene3D G3DSA:3.40.50.300 75 202 6.0E-11 T 28-03-2018 SMD44_RS24105 94bbc4b42b8dce8a8f5061558aea9fba 32 SMART SM01155 1 32 3.8E-5 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS24105 94bbc4b42b8dce8a8f5061558aea9fba 32 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 2 30 2.4E-9 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20790 6abf0782999af74ce58445f6732b6a51 300 SUPERFAMILY SSF51679 17 296 1.31E-52 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS20790 6abf0782999af74ce58445f6732b6a51 300 Gene3D G3DSA:3.20.20.30 19 300 1.9E-58 T 28-03-2018 SMD44_RS20790 6abf0782999af74ce58445f6732b6a51 300 Pfam PF00296 Luciferase-like monooxygenase 21 239 3.9E-43 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS07380 89e574119aaa1b2272993b255a9200a4 293 SMART SM00382 32 218 3.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS07380 89e574119aaa1b2272993b255a9200a4 293 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS07380 89e574119aaa1b2272993b255a9200a4 293 Gene3D G3DSA:3.40.50.300 4 257 2.7E-66 T 28-03-2018 SMD44_RS07380 89e574119aaa1b2272993b255a9200a4 293 Pfam PF00005 ABC transporter 24 161 1.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS07380 89e574119aaa1b2272993b255a9200a4 293 SUPERFAMILY SSF52540 4 229 4.41E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29955 395fc19d3e843c2cba2a4931e50e18eb 308 Gene3D G3DSA:3.20.20.220 7 307 2.0E-66 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SMD44_RS29955 395fc19d3e843c2cba2a4931e50e18eb 308 SUPERFAMILY SSF51730 35 305 7.85E-67 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SMD44_RS29955 395fc19d3e843c2cba2a4931e50e18eb 308 Pfam PF01619 Proline dehydrogenase 50 299 2.9E-28 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 SMD44_RS29955 395fc19d3e843c2cba2a4931e50e18eb 308 PIRSF PIRSF000196 1 308 2.9E-114 T 28-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 PIRSF PIRSF002191 1 116 1.4E-48 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 28.73 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 SUPERFAMILY SSF50104 3 115 6.62E-45 T 28-03-2018 IPR008991 Translation protein SH3-like domain SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 Pfam PF01245 Ribosomal protein L19 4 113 3.8E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30495 322617e237cb8ff7c306f5852d34be12 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 1.2E-47 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 Pfam PF00106 short chain dehydrogenase 11 187 4.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 SUPERFAMILY SSF51735 10 208 1.5E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 4.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 4.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 8.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 8.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 8.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 8.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 8.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01610 c8aeb4018d863760e50a8e14b050e0bb 236 Gene3D G3DSA:3.40.50.720 8 216 6.9E-42 T 28-03-2018 SMD44_RS30150 58e9bc7b4bdb492f09d1f9461c177305 1012 Gene3D G3DSA:3.40.50.300 3 269 0.06 T 28-03-2018 SMD44_RS30150 58e9bc7b4bdb492f09d1f9461c177305 1012 Gene3D G3DSA:3.40.50.300 270 297 0.0034 T 28-03-2018 SMD44_RS30150 58e9bc7b4bdb492f09d1f9461c177305 1012 Gene3D G3DSA:3.80.10.10 799 977 7.3E-6 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMD44_RS30150 58e9bc7b4bdb492f09d1f9461c177305 1012 SUPERFAMILY SSF52540 280 412 4.56E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30150 58e9bc7b4bdb492f09d1f9461c177305 1012 Pfam PF05729 NACHT domain 287 446 7.1E-21 T 28-03-2018 SMD44_RS30150 58e9bc7b4bdb492f09d1f9461c177305 1012 Gene3D G3DSA:3.40.50.300 298 479 4.4E-6 T 28-03-2018 SMD44_RS30150 58e9bc7b4bdb492f09d1f9461c177305 1012 SUPERFAMILY SSF52058 832 967 5.1E-5 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMD44_RS34365 a03f09b5971146d1d4fd3d6bbfafd586 400 Gene3D G3DSA:3.30.530.20 114 299 1.4E-20 T 28-03-2018 IPR023393 START-like domain SMD44_RS34365 a03f09b5971146d1d4fd3d6bbfafd586 400 SUPERFAMILY SSF55961 137 263 2.85E-16 T 28-03-2018 SMD44_RS34365 a03f09b5971146d1d4fd3d6bbfafd586 400 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 139 258 1.3E-12 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 SMD44_RS41210 d0280edbf87bef73f602a168791248c3 79 Pfam PF00550 Phosphopantetheine attachment site 6 71 1.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS41210 d0280edbf87bef73f602a168791248c3 79 SUPERFAMILY SSF47336 6 75 1.7E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS41210 d0280edbf87bef73f602a168791248c3 79 Gene3D G3DSA:1.10.1200.10 3 77 4.8E-16 T 28-03-2018 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 Gene3D G3DSA:1.10.390.10 433 610 4.9E-48 T 28-03-2018 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 432 606 5.7E-50 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 SUPERFAMILY SSF55486 282 606 3.3E-76 T 28-03-2018 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 Gene3D G3DSA:3.10.170.10 279 431 1.5E-45 T 28-03-2018 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 283 428 4.6E-47 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 383 403 2.1E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 419 435 2.1E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 440 451 2.1E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 507 523 2.1E-17 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD44_RS29490 167d8ef29841a761cb16ebc50ef41b76 610 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 139 186 9.4E-18 T 28-03-2018 IPR011096 FTP domain SMD44_RS29655 9a7c2a9e52af5528485a512615dfd6d7 420 Pfam PF00464 Serine hydroxymethyltransferase 9 389 2.8E-163 T 28-03-2018 SMD44_RS29655 9a7c2a9e52af5528485a512615dfd6d7 420 Gene3D G3DSA:3.40.640.10 37 273 1.2E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS29655 9a7c2a9e52af5528485a512615dfd6d7 420 Gene3D G3DSA:3.90.1150.10 274 416 2.3E-52 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS29655 9a7c2a9e52af5528485a512615dfd6d7 420 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD44_RS29655 9a7c2a9e52af5528485a512615dfd6d7 420 SUPERFAMILY SSF53383 5 418 4.95E-170 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS29655 9a7c2a9e52af5528485a512615dfd6d7 420 PIRSF PIRSF000412 1 414 2.7E-156 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD44_RS29655 9a7c2a9e52af5528485a512615dfd6d7 420 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 49.997 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD44_RS19080 e0b3b582f51baae716355e08eac6cc8f 268 SUPERFAMILY SSF53335 18 176 5.03E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS19080 e0b3b582f51baae716355e08eac6cc8f 268 Gene3D G3DSA:3.40.50.150 29 254 6.7E-13 T 28-03-2018 SMD44_RS20910 9d24386bf1eeac556c8f48da70c9cd08 223 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 171 1.5E-14 T 28-03-2018 SMD44_RS20910 9d24386bf1eeac556c8f48da70c9cd08 223 SUPERFAMILY SSF56784 3 201 5.42E-22 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS20910 9d24386bf1eeac556c8f48da70c9cd08 223 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 173 1.6E-14 T 28-03-2018 SMD44_RS20910 9d24386bf1eeac556c8f48da70c9cd08 223 Gene3D G3DSA:3.40.50.1000 1 202 1.4E-15 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 3.2E-10 T 28-03-2018 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 3.2E-10 T 28-03-2018 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 3.2E-10 T 28-03-2018 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 SUPERFAMILY SSF51905 1 169 1.89E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 SUPERFAMILY SSF51905 271 386 1.89E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 SUPERFAMILY SSF54373 177 272 2.67E-26 T 28-03-2018 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 Gene3D G3DSA:3.50.50.60 1 153 8.3E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 Pfam PF01494 FAD binding domain 1 339 4.1E-54 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 Gene3D G3DSA:3.30.9.10 314 390 1.0E-18 T 28-03-2018 SMD44_RS22355 701f4ee0a03c19cdfb90f538d3b19001 390 Gene3D G3DSA:3.30.9.10 154 295 2.3E-39 T 28-03-2018 SMD44_RS34825 01553be45f12a37958a5abccf5da60ac 444 Pfam PF10011 Predicted membrane protein (DUF2254) 29 396 3.4E-102 T 28-03-2018 IPR018723 Protein of unknown function DUF2254, membrane SMD44_RS01640 6d2b04a01795649f35559378ae21c447 104 SMART SM00418 16 95 7.0E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS01640 6d2b04a01795649f35559378ae21c447 104 Pfam PF12840 Helix-turn-helix domain 16 74 4.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01640 6d2b04a01795649f35559378ae21c447 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 1.3E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS01640 6d2b04a01795649f35559378ae21c447 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.3E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS01640 6d2b04a01795649f35559378ae21c447 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 1.3E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS01640 6d2b04a01795649f35559378ae21c447 104 Gene3D G3DSA:1.10.10.10 1 102 1.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01640 6d2b04a01795649f35559378ae21c447 104 SUPERFAMILY SSF46785 4 95 1.06E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31025 bafbdb4a93df00af3c657dafe92b6b02 511 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 31 105 1.1E-19 T 28-03-2018 IPR024962 YukD-like SMD44_RS31025 bafbdb4a93df00af3c657dafe92b6b02 511 PIRSF PIRSF017804 23 511 4.4E-148 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD SMD44_RS31025 bafbdb4a93df00af3c657dafe92b6b02 511 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 34 507 2.4E-53 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD SMD44_RS20390 f30dd1d49ed18c757a37a177cf3ae8ba 248 SUPERFAMILY SSF55399 147 243 3.66E-26 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS20390 f30dd1d49ed18c757a37a177cf3ae8ba 248 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 159 234 7.0E-11 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS20390 f30dd1d49ed18c757a37a177cf3ae8ba 248 Pfam PF00720 Subtilisin inhibitor-like 147 222 4.4E-13 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS20390 f30dd1d49ed18c757a37a177cf3ae8ba 248 Gene3D G3DSA:3.30.350.10 132 241 5.0E-30 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS20390 f30dd1d49ed18c757a37a177cf3ae8ba 248 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 163 180 - T 28-03-2018 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 SMD44_RS32595 4d896315759f320ba13ba0e4702c1590 863 Gene3D G3DSA:1.25.40.10 734 850 0.085 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32595 4d896315759f320ba13ba0e4702c1590 863 Gene3D G3DSA:1.25.40.120 1 431 6.8E-13 T 28-03-2018 SMD44_RS32595 4d896315759f320ba13ba0e4702c1590 863 Gene3D G3DSA:1.25.40.10 492 733 0.037 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32595 4d896315759f320ba13ba0e4702c1590 863 SUPERFAMILY SSF48452 87 140 6.95E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32595 4d896315759f320ba13ba0e4702c1590 863 SUPERFAMILY SSF48452 290 357 6.95E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 SUPERFAMILY SSF82866 484 703 3.53E-28 T 28-03-2018 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 PRINTS PR00702 Acriflavin resistance protein family signature 304 327 7.4E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 PRINTS PR00702 Acriflavin resistance protein family signature 176 199 7.4E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 PRINTS PR00702 Acriflavin resistance protein family signature 229 253 7.4E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 Pfam PF03176 MMPL family 45 374 5.7E-77 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 Pfam PF03176 MMPL family 437 709 1.2E-35 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 SUPERFAMILY SSF82866 123 334 4.71E-31 T 28-03-2018 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 Gene3D G3DSA:1.20.1640.10 120 334 3.1E-36 T 28-03-2018 SMD44_RS08845 75575915bd33a65138eda8d5e148c5f4 747 Gene3D G3DSA:1.20.1640.10 463 701 2.8E-32 T 28-03-2018 SMD44_RS00575 a2ad6c540fb40b82ec4b7945a928deae 295 Pfam PF13460 NAD(P)H-binding 14 182 6.0E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS00575 a2ad6c540fb40b82ec4b7945a928deae 295 SUPERFAMILY SSF51735 6 247 1.96E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS00575 a2ad6c540fb40b82ec4b7945a928deae 295 Gene3D G3DSA:3.40.50.720 6 286 8.4E-27 T 28-03-2018 SMD44_RS01935 7a4edb92b1062f1747a4e299ac690623 421 SMART SM00825 Beta-ketoacyl synthase 2 399 1.1E-5 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS01935 7a4edb92b1062f1747a4e299ac690623 421 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 252 3.4E-30 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS01935 7a4edb92b1062f1747a4e299ac690623 421 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 376 1.8E-20 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS01935 7a4edb92b1062f1747a4e299ac690623 421 SUPERFAMILY SSF53901 2 103 3.89E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01935 7a4edb92b1062f1747a4e299ac690623 421 SUPERFAMILY SSF53901 140 374 3.89E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01935 7a4edb92b1062f1747a4e299ac690623 421 Gene3D G3DSA:3.40.47.10 268 421 9.5E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01935 7a4edb92b1062f1747a4e299ac690623 421 Gene3D G3DSA:3.40.47.10 1 264 8.5E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS26500 d76d3d169fee874e5394e819c68b91c4 108 Pfam PF13620 Carboxypeptidase regulatory-like domain 19 96 8.3E-11 T 28-03-2018 SMD44_RS26500 d76d3d169fee874e5394e819c68b91c4 108 Gene3D G3DSA:2.60.40.1120 18 107 1.7E-8 T 28-03-2018 SMD44_RS26500 d76d3d169fee874e5394e819c68b91c4 108 SUPERFAMILY SSF49464 19 98 8.63E-11 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMD44_RS12610 3da22339f231fc0cf510d3803a50bf13 278 SMART SM00530 15 70 3.3E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS12610 3da22339f231fc0cf510d3803a50bf13 278 SUPERFAMILY SSF47413 8 66 2.82E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS12610 3da22339f231fc0cf510d3803a50bf13 278 Gene3D G3DSA:1.10.260.40 1 69 7.4E-16 T 28-03-2018 SMD44_RS12610 3da22339f231fc0cf510d3803a50bf13 278 Pfam PF13560 Helix-turn-helix domain 11 68 2.5E-15 T 28-03-2018 SMD44_RS00955 ebb9025b47399bf7ffac78b8cd591277 278 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 87 101 7.9E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS00955 ebb9025b47399bf7ffac78b8cd591277 278 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 21 29 7.9E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS00955 ebb9025b47399bf7ffac78b8cd591277 278 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 47 58 7.9E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD44_RS00955 ebb9025b47399bf7ffac78b8cd591277 278 Gene3D G3DSA:3.40.50.1820 3 272 2.1E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS00955 ebb9025b47399bf7ffac78b8cd591277 278 SUPERFAMILY SSF53474 4 273 1.58E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS00955 ebb9025b47399bf7ffac78b8cd591277 278 Pfam PF00561 alpha/beta hydrolase fold 19 134 1.6E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS39700 109a015d46d381f566936e4fd81cb752 265 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 76 5.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS39700 109a015d46d381f566936e4fd81cb752 265 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 96 259 2.3E-22 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS39700 109a015d46d381f566936e4fd81cb752 265 Gene3D G3DSA:1.10.10.60 9 82 2.4E-15 T 28-03-2018 SMD44_RS39700 109a015d46d381f566936e4fd81cb752 265 SUPERFAMILY SSF48498 221 260 2.67E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS39700 109a015d46d381f566936e4fd81cb752 265 SUPERFAMILY SSF48498 96 170 2.67E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS39700 109a015d46d381f566936e4fd81cb752 265 Gene3D G3DSA:1.10.357.10 83 261 4.0E-39 T 28-03-2018 SMD44_RS39700 109a015d46d381f566936e4fd81cb752 265 SUPERFAMILY SSF46689 24 83 4.79E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS20450 175315f40dc80e3a89570cc37d13b867 359 Gene3D G3DSA:1.20.140.10 178 356 6.0E-24 T 28-03-2018 SMD44_RS20450 175315f40dc80e3a89570cc37d13b867 359 SUPERFAMILY SSF56645 1 186 1.2E-17 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS20450 175315f40dc80e3a89570cc37d13b867 359 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 204 329 4.7E-19 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS20450 175315f40dc80e3a89570cc37d13b867 359 Gene3D G3DSA:1.10.540.10 1 114 1.1E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS20450 175315f40dc80e3a89570cc37d13b867 359 SUPERFAMILY SSF47203 202 335 2.74E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS20450 175315f40dc80e3a89570cc37d13b867 359 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 107 7.5E-7 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS18405 fb00fc03f0b5346762b9ec83ff830d22 319 Gene3D G3DSA:3.60.15.10 4 293 5.4E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS18405 fb00fc03f0b5346762b9ec83ff830d22 319 SUPERFAMILY SSF56281 60 290 1.07E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS18405 fb00fc03f0b5346762b9ec83ff830d22 319 SMART SM00849 58 281 2.1E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS18405 fb00fc03f0b5346762b9ec83ff830d22 319 Pfam PF00753 Metallo-beta-lactamase superfamily 57 281 5.5E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS14420 b55983d8aabf5b90a724bb95a57bc59d 318 SUPERFAMILY SSF103481 179 284 4.71E-16 T 28-03-2018 SMD44_RS14420 b55983d8aabf5b90a724bb95a57bc59d 318 Pfam PF00892 EamA-like transporter family 144 276 6.5E-23 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS14420 b55983d8aabf5b90a724bb95a57bc59d 318 Pfam PF00892 EamA-like transporter family 6 133 2.4E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS14420 b55983d8aabf5b90a724bb95a57bc59d 318 SUPERFAMILY SSF103481 46 135 1.7E-11 T 28-03-2018 SMD44_RS23995 9c99e34b4eac29821864c37a39b0acd8 274 Gene3D G3DSA:3.20.20.150 7 269 1.3E-50 T 28-03-2018 SMD44_RS23995 9c99e34b4eac29821864c37a39b0acd8 274 Pfam PF01261 Xylose isomerase-like TIM barrel 29 216 1.1E-16 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS23995 9c99e34b4eac29821864c37a39b0acd8 274 SUPERFAMILY SSF51658 8 269 1.38E-46 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 SUPERFAMILY SSF46689 233 281 3.84E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 Pfam PF01965 DJ-1/PfpI family 58 192 3.4E-14 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 Gene3D G3DSA:1.10.10.60 249 284 3.2E-7 T 28-03-2018 SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 Pfam PF12833 Helix-turn-helix domain 254 332 6.2E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 SUPERFAMILY SSF46689 285 335 1.48E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 Gene3D G3DSA:1.10.10.60 285 348 9.5E-14 T 28-03-2018 SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 SMART SM00342 248 331 2.3E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 SUPERFAMILY SSF52317 25 213 2.39E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS15025 38e74618dfd48092c0b6c72f0b4be2be 438 Gene3D G3DSA:3.40.50.880 18 248 3.3E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS11775 8e7072de2a305a3220d97d2eea0474b8 331 SUPERFAMILY SSF51735 1 306 1.23E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS11775 8e7072de2a305a3220d97d2eea0474b8 331 Gene3D G3DSA:3.40.50.720 2 306 6.6E-28 T 28-03-2018 SMD44_RS11775 8e7072de2a305a3220d97d2eea0474b8 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 206 6.1E-7 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 PRINTS PR01036 Tetracycline resistance protein TetB signature 39 63 1.6E-9 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 PRINTS PR01036 Tetracycline resistance protein TetB signature 160 184 1.6E-9 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 150 1.6E-9 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 PRINTS PR01036 Tetracycline resistance protein TetB signature 430 449 1.6E-9 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Pfam PF07690 Major Facilitator Superfamily 40 439 5.5E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 SUPERFAMILY SSF49478 773 838 7.06E-11 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Gene3D G3DSA:2.60.40.10 768 849 4.6E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 SUPERFAMILY SSF49464 688 775 2.16E-9 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 SUPERFAMILY SSF103473 499 523 4.84E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 SUPERFAMILY SSF103473 26 220 4.84E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 SUPERFAMILY SSF103473 277 449 4.84E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Gene3D G3DSA:1.20.1250.20 281 538 8.6E-32 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Gene3D G3DSA:1.20.1250.20 35 223 9.3E-30 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Gene3D G3DSA:2.60.40.1120 596 676 4.6E-9 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 SUPERFAMILY SSF49464 605 697 1.33E-11 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Gene3D G3DSA:2.60.40.1120 687 767 3.5E-11 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Pfam PF13620 Carboxypeptidase regulatory-like domain 688 767 6.1E-11 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Pfam PF13620 Carboxypeptidase regulatory-like domain 773 838 8.6E-10 T 28-03-2018 SMD44_RS20280 88c9a88ed0c83b7009fa797e844b44b2 855 Pfam PF13620 Carboxypeptidase regulatory-like domain 605 673 8.1E-11 T 28-03-2018 SMD44_RS08155 7ef71a99612bcd15d7726c662b7ec601 72 Pfam PF05639 Pup-like protein 4 72 3.6E-31 T 28-03-2018 IPR008515 Ubiquitin-like, Pup SMD44_RS08155 7ef71a99612bcd15d7726c662b7ec601 72 Gene3D G3DSA:1.20.120.20 2 72 0.001 T 28-03-2018 SMD44_RS08155 7ef71a99612bcd15d7726c662b7ec601 72 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 41 72 2.9E-21 T 28-03-2018 IPR008515 Ubiquitin-like, Pup SMD44_RS08155 7ef71a99612bcd15d7726c662b7ec601 72 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 72 17.744 T 28-03-2018 IPR008515 Ubiquitin-like, Pup SMD44_RS27420 9dee2a54809d7b0d20a96e120153eb7e 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 SMD44_RS27420 9dee2a54809d7b0d20a96e120153eb7e 253 SUPERFAMILY SSF64005 21 247 1.83E-74 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS27420 9dee2a54809d7b0d20a96e120153eb7e 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 253 36.547 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS27420 9dee2a54809d7b0d20a96e120153eb7e 253 Gene3D G3DSA:3.40.1180.10 10 253 1.3E-85 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS27420 9dee2a54809d7b0d20a96e120153eb7e 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 31 252 2.0E-71 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS27420 9dee2a54809d7b0d20a96e120153eb7e 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 252 4.3E-66 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD44_RS02855 1827903acf2bfbabae8a9a6c903ecc66 290 SUPERFAMILY SSF51430 18 289 2.88E-77 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS02855 1827903acf2bfbabae8a9a6c903ecc66 290 Pfam PF00248 Aldo/keto reductase family 26 288 5.5E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS02855 1827903acf2bfbabae8a9a6c903ecc66 290 Gene3D G3DSA:3.20.20.100 17 290 5.3E-78 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS02855 1827903acf2bfbabae8a9a6c903ecc66 290 PRINTS PR00069 Aldo-keto reductase signature 121 139 1.0E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS02855 1827903acf2bfbabae8a9a6c903ecc66 290 PRINTS PR00069 Aldo-keto reductase signature 56 80 1.0E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS02855 1827903acf2bfbabae8a9a6c903ecc66 290 PRINTS PR00069 Aldo-keto reductase signature 152 169 1.0E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS02855 1827903acf2bfbabae8a9a6c903ecc66 290 PRINTS PR00069 Aldo-keto reductase signature 223 247 1.0E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS22545 338c4a6a3a137fe125b88738bb82b5a0 123 SUPERFAMILY SSF50022 6 87 6.89E-14 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS22545 338c4a6a3a137fe125b88738bb82b5a0 123 Gene3D G3DSA:2.102.10.10 66 122 0.046 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS22545 338c4a6a3a137fe125b88738bb82b5a0 123 Gene3D G3DSA:2.102.10.10 6 65 2.8E-6 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS05915 20be29ebf5fd04c3bdcee414d435780f 466 Gene3D G3DSA:1.20.1250.20 23 216 5.3E-27 T 28-03-2018 SMD44_RS05915 20be29ebf5fd04c3bdcee414d435780f 466 ProSitePatterns PS00216 Sugar transport proteins signature 1. 82 99 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS05915 20be29ebf5fd04c3bdcee414d435780f 466 SUPERFAMILY SSF103473 24 215 9.42E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS05915 20be29ebf5fd04c3bdcee414d435780f 466 SUPERFAMILY SSF103473 260 454 9.42E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS05915 20be29ebf5fd04c3bdcee414d435780f 466 Pfam PF07690 Major Facilitator Superfamily 33 418 9.2E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS05915 20be29ebf5fd04c3bdcee414d435780f 466 Gene3D G3DSA:1.20.1250.20 272 465 1.8E-21 T 28-03-2018 SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 320 2.2E-29 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 SUPERFAMILY SSF52467 184 346 2.53E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 Gene3D G3DSA:3.40.50.970 334 536 1.6E-41 T 28-03-2018 SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 SUPERFAMILY SSF52518 360 543 2.44E-59 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 Gene3D G3DSA:3.40.50.1220 187 333 6.2E-32 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 529 1.1E-40 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 Gene3D G3DSA:3.40.50.970 1 186 4.3E-44 T 28-03-2018 SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 SUPERFAMILY SSF52518 1 177 3.44E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS32980 c160e20dd4934447cb5e3d94dbd71525 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 4.3E-42 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD44_RS14470 1ea338785ac9fabac3ec7ec9718d4de9 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 296 1.7E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS14470 1ea338785ac9fabac3ec7ec9718d4de9 303 SUPERFAMILY SSF161098 30 303 6.07E-74 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS14470 1ea338785ac9fabac3ec7ec9718d4de9 303 Gene3D G3DSA:1.10.3720.10 24 290 1.6E-54 T 28-03-2018 SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 Pfam PF03572 Peptidase family S41 225 380 4.6E-37 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 SMART SM00228 117 197 2.8E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 Gene3D G3DSA:3.30.750.44 42 127 4.0E-4 T 28-03-2018 SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 133 192 5.5E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 SUPERFAMILY SSF50156 106 215 1.86E-19 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 SUPERFAMILY SSF52096 91 143 4.14E-44 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 SUPERFAMILY SSF52096 216 385 4.14E-44 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 SMART SM00245 197 381 6.5E-37 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 Gene3D G3DSA:2.30.42.10 128 205 2.0E-19 T 28-03-2018 SMD44_RS16045 1e4e1eb5aed8d8ab2afb177a162b4663 399 Gene3D G3DSA:3.90.226.10 206 393 3.9E-45 T 28-03-2018 SMD44_RS08300 0ed73ebf9f16c92eca5a27571028e720 294 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 18 294 1.7E-104 T 28-03-2018 IPR022292 Conserved hypothetical protein CHP03843 SMD44_RS37230 1daa9aedf403d69fbd4e9250f73619da 389 Gene3D G3DSA:3.30.565.10 198 385 1.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS37230 1daa9aedf403d69fbd4e9250f73619da 389 SUPERFAMILY SSF55874 257 383 1.43E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS37230 1daa9aedf403d69fbd4e9250f73619da 389 Pfam PF07730 Histidine kinase 169 234 8.2E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS37230 1daa9aedf403d69fbd4e9250f73619da 389 SMART SM00387 282 386 0.001 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS37230 1daa9aedf403d69fbd4e9250f73619da 389 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 384 9.9E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09900 7f55bbf5a9269ef6880d11b605235db5 379 SUPERFAMILY SSF50494 182 358 1.35E-14 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS09900 7f55bbf5a9269ef6880d11b605235db5 379 Gene3D G3DSA:2.40.10.10 264 372 7.3E-12 T 28-03-2018 SMD44_RS06075 13d2655022b815897ed16875e642d927 280 SUPERFAMILY SSF51735 18 279 9.51E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS06075 13d2655022b815897ed16875e642d927 280 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 279 6.7E-35 T 28-03-2018 SMD44_RS06075 13d2655022b815897ed16875e642d927 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 230 1.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06075 13d2655022b815897ed16875e642d927 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 1.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06075 13d2655022b815897ed16875e642d927 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 243 263 1.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06075 13d2655022b815897ed16875e642d927 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 124 1.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06075 13d2655022b815897ed16875e642d927 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 211 1.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS06075 13d2655022b815897ed16875e642d927 280 Gene3D G3DSA:3.40.50.720 3 280 5.3E-49 T 28-03-2018 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 Gene3D G3DSA:3.30.565.10 365 527 2.8E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 Gene3D G3DSA:1.10.287.130 308 364 5.3E-8 T 28-03-2018 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 SUPERFAMILY SSF47384 301 380 2.55E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 Pfam PF00512 His Kinase A (phospho-acceptor) domain 319 379 3.2E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 526 1.5E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 SMART SM00387 418 528 2.3E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 SMART SM00304 263 317 3.6E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 467 2.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 481 2.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 2.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 2.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 SMART SM00388 318 379 1.1E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS29050 292104b6a8c9cdc3732e2402f06f1f2d 532 SUPERFAMILY SSF55874 369 526 2.75E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11780 2f6e2192e2936097500f7cd48ccac4a7 715 Gene3D G3DSA:1.20.1640.10 114 328 2.4E-34 T 28-03-2018 SMD44_RS11780 2f6e2192e2936097500f7cd48ccac4a7 715 Gene3D G3DSA:1.20.1640.10 460 683 1.1E-36 T 28-03-2018 SMD44_RS11780 2f6e2192e2936097500f7cd48ccac4a7 715 Pfam PF03176 MMPL family 80 321 4.5E-45 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS11780 2f6e2192e2936097500f7cd48ccac4a7 715 Pfam PF03176 MMPL family 440 689 4.9E-36 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS11780 2f6e2192e2936097500f7cd48ccac4a7 715 SUPERFAMILY SSF82866 101 321 1.24E-33 T 28-03-2018 SMD44_RS11780 2f6e2192e2936097500f7cd48ccac4a7 715 SUPERFAMILY SSF82866 448 685 1.07E-33 T 28-03-2018 SMD44_RS33285 5408ba15826393d4c3e11315fdc7c02b 568 Gene3D G3DSA:3.40.50.980 46 216 6.2E-33 T 28-03-2018 SMD44_RS33285 5408ba15826393d4c3e11315fdc7c02b 568 SUPERFAMILY SSF56801 25 557 9.68E-129 T 28-03-2018 SMD44_RS33285 5408ba15826393d4c3e11315fdc7c02b 568 Gene3D G3DSA:3.40.50.980 217 364 5.0E-34 T 28-03-2018 SMD44_RS33285 5408ba15826393d4c3e11315fdc7c02b 568 Gene3D G3DSA:3.30.300.30 454 566 8.4E-21 T 28-03-2018 SMD44_RS33285 5408ba15826393d4c3e11315fdc7c02b 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 467 544 1.5E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS33285 5408ba15826393d4c3e11315fdc7c02b 568 Pfam PF00501 AMP-binding enzyme 55 458 3.0E-75 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS33285 5408ba15826393d4c3e11315fdc7c02b 568 Gene3D G3DSA:2.30.38.10 365 451 1.2E-20 T 28-03-2018 SMD44_RS09800 4c17ab7c4312f13c32090114e5f899d7 329 SUPERFAMILY SSF51569 42 327 1.15E-60 T 28-03-2018 SMD44_RS09800 4c17ab7c4312f13c32090114e5f899d7 329 Gene3D G3DSA:3.20.20.70 30 329 7.5E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS09800 4c17ab7c4312f13c32090114e5f899d7 329 Pfam PF00701 Dihydrodipicolinate synthetase family 40 324 3.2E-38 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09800 4c17ab7c4312f13c32090114e5f899d7 329 PIRSF PIRSF001365 36 329 3.2E-54 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09800 4c17ab7c4312f13c32090114e5f899d7 329 SMART SM01130 38 328 7.7E-54 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS03005 b661739d6b3ab2351ceefee3a42f9286 277 Pfam PF03649 Uncharacterised protein family (UPF0014) 23 250 1.2E-42 T 28-03-2018 IPR005226 UPF0014 family SMD44_RS42515 00b4052394708e93a2a23da5e00af523 174 SUPERFAMILY SSF103088 57 171 4.58E-29 T 28-03-2018 IPR006665 OmpA-like domain SMD44_RS42515 00b4052394708e93a2a23da5e00af523 174 Pfam PF00691 OmpA family 68 165 4.5E-18 T 28-03-2018 IPR006665 OmpA-like domain SMD44_RS42515 00b4052394708e93a2a23da5e00af523 174 PRINTS PR01021 OMPA domain signature 69 91 1.7E-9 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD44_RS42515 00b4052394708e93a2a23da5e00af523 174 PRINTS PR01021 OMPA domain signature 100 115 1.7E-9 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD44_RS42515 00b4052394708e93a2a23da5e00af523 174 PRINTS PR01021 OMPA domain signature 115 131 1.7E-9 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD44_RS42515 00b4052394708e93a2a23da5e00af523 174 Gene3D G3DSA:3.30.1330.60 22 174 1.6E-32 T 28-03-2018 IPR006665 OmpA-like domain SMD44_RS18255 bf4af16b4068f8245402105b39a1f8bc 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 7.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18255 bf4af16b4068f8245402105b39a1f8bc 202 SUPERFAMILY SSF46689 11 86 2.26E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS18255 bf4af16b4068f8245402105b39a1f8bc 202 Gene3D G3DSA:1.10.10.60 4 56 1.6E-19 T 28-03-2018 SMD44_RS18255 bf4af16b4068f8245402105b39a1f8bc 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18255 bf4af16b4068f8245402105b39a1f8bc 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18255 bf4af16b4068f8245402105b39a1f8bc 202 Gene3D G3DSA:1.10.10.60 57 145 7.2E-8 T 28-03-2018 SMD44_RS12380 3ddc5c4f3b6de3538dc52f3c10724c89 492 Gene3D G3DSA:3.40.309.10 268 463 4.9E-65 T 28-03-2018 SMD44_RS12380 3ddc5c4f3b6de3538dc52f3c10724c89 492 SUPERFAMILY SSF53720 4 479 4.97E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS12380 3ddc5c4f3b6de3538dc52f3c10724c89 492 Pfam PF00171 Aldehyde dehydrogenase family 24 476 5.1E-148 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS12380 3ddc5c4f3b6de3538dc52f3c10724c89 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS12380 3ddc5c4f3b6de3538dc52f3c10724c89 492 Gene3D G3DSA:3.40.605.10 1 267 2.4E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS30950 6a288c3ce3fed451d4d1dd32d662ac21 511 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 507 8.6E-82 T 28-03-2018 IPR007795 Type VII secretion system EccB SMD44_RS30950 6a288c3ce3fed451d4d1dd32d662ac21 511 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 4 447 1.7E-53 T 28-03-2018 IPR007795 Type VII secretion system EccB SMD44_RS11785 093f2f632a6000ba6c18a60f98c60d7e 425 Gene3D G3DSA:3.30.565.10 298 425 2.0E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11785 093f2f632a6000ba6c18a60f98c60d7e 425 Pfam PF13796 Putative sensor 18 202 2.9E-19 T 28-03-2018 IPR025828 Putative sensor domain SMD44_RS11785 093f2f632a6000ba6c18a60f98c60d7e 425 Pfam PF07730 Histidine kinase 234 301 9.5E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS11785 093f2f632a6000ba6c18a60f98c60d7e 425 SUPERFAMILY SSF55874 310 421 2.49E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11785 093f2f632a6000ba6c18a60f98c60d7e 425 SMART SM00387 334 424 0.0076 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS43890 7265e43fbfab5d62855c03144efb7b25 580 SUPERFAMILY SSF110849 92 168 1.74E-8 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS43890 7265e43fbfab5d62855c03144efb7b25 580 Pfam PF02195 ParB-like nuclease domain 38 88 3.3E-6 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS43890 7265e43fbfab5d62855c03144efb7b25 580 Gene3D G3DSA:3.90.1530.10 5 91 2.4E-9 T 28-03-2018 SMD44_RS43890 7265e43fbfab5d62855c03144efb7b25 580 Gene3D G3DSA:3.90.1530.10 92 186 2.0E-10 T 28-03-2018 SMD44_RS43890 7265e43fbfab5d62855c03144efb7b25 580 SUPERFAMILY SSF110849 24 88 1.57E-8 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS30815 b0eb8be58ce574f038ce3508ee95165a 282 Gene3D G3DSA:3.40.630.30 3 280 2.4E-23 T 28-03-2018 SMD44_RS30815 b0eb8be58ce574f038ce3508ee95165a 282 SUPERFAMILY SSF55729 7 277 7.44E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS30815 b0eb8be58ce574f038ce3508ee95165a 282 Pfam PF13312 Domain of unknown function (DUF4081) 48 152 7.3E-42 T 28-03-2018 IPR025289 Domain of unknown function DUF4081 SMD44_RS30815 b0eb8be58ce574f038ce3508ee95165a 282 Pfam PF00583 Acetyltransferase (GNAT) family 185 271 7.3E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS30815 b0eb8be58ce574f038ce3508ee95165a 282 PIRSF PIRSF021603 1 282 3.7E-140 T 28-03-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like SMD44_RS25000 2959aac5afa0ca805b3af32f64049f14 314 Pfam PF00196 Bacterial regulatory proteins, luxR family 252 291 8.4E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25000 2959aac5afa0ca805b3af32f64049f14 314 Gene3D G3DSA:1.10.10.10 58 306 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25000 2959aac5afa0ca805b3af32f64049f14 314 SUPERFAMILY SSF46894 249 302 7.48E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS25000 2959aac5afa0ca805b3af32f64049f14 314 SMART SM00421 245 302 0.0016 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS25000 2959aac5afa0ca805b3af32f64049f14 314 Gene3D G3DSA:1.10.10.10 13 57 0.12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 Gene3D G3DSA:1.10.10.60 253 290 9.5E-14 T 28-03-2018 SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 SUPERFAMILY SSF52317 22 216 1.67E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 SUPERFAMILY SSF46689 236 286 5.82E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 Gene3D G3DSA:1.10.10.60 291 341 1.3E-7 T 28-03-2018 SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 Gene3D G3DSA:3.40.50.880 18 252 2.4E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 Pfam PF12833 Helix-turn-helix domain 258 336 4.7E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 SUPERFAMILY SSF46689 289 338 9.86E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 Pfam PF01965 DJ-1/PfpI family 24 195 2.2E-16 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS24050 2ccc2a18a510ea445129f6a162964ee8 356 SMART SM00342 252 335 1.8E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS18730 8e623b40410c66c3e4aed83140ae9d09 353 Gene3D G3DSA:1.10.101.10 106 171 1.4E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS18730 8e623b40410c66c3e4aed83140ae9d09 353 Gene3D G3DSA:2.40.50.100 42 99 0.026 T 28-03-2018 SMD44_RS18730 8e623b40410c66c3e4aed83140ae9d09 353 Pfam PF01471 Putative peptidoglycan binding domain 117 168 1.8E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS18730 8e623b40410c66c3e4aed83140ae9d09 353 SUPERFAMILY SSF47090 104 168 2.62E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS21615 333d6555539556da3998352fd5de1f1e 396 Pfam PF00465 Iron-containing alcohol dehydrogenase 22 303 2.0E-23 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 SMD44_RS21615 333d6555539556da3998352fd5de1f1e 396 Gene3D G3DSA:3.40.50.1970 7 195 1.5E-20 T 28-03-2018 SMD44_RS21615 333d6555539556da3998352fd5de1f1e 396 SUPERFAMILY SSF56796 17 301 1.14E-24 T 28-03-2018 SMD44_RS09860 f2b7033b66593347dafbb196655dc622 329 Gene3D G3DSA:3.40.50.720 159 280 3.6E-18 T 28-03-2018 SMD44_RS09860 f2b7033b66593347dafbb196655dc622 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS09860 f2b7033b66593347dafbb196655dc622 329 SUPERFAMILY SSF51735 138 299 1.35E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09860 f2b7033b66593347dafbb196655dc622 329 Pfam PF00107 Zinc-binding dehydrogenase 171 289 2.0E-13 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS09860 f2b7033b66593347dafbb196655dc622 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 129 1.7E-32 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS09860 f2b7033b66593347dafbb196655dc622 329 Gene3D G3DSA:3.90.180.10 1 158 1.3E-48 T 28-03-2018 SMD44_RS09860 f2b7033b66593347dafbb196655dc622 329 SUPERFAMILY SSF50129 2 169 7.76E-51 T 28-03-2018 IPR011032 GroES-like SMD44_RS09860 f2b7033b66593347dafbb196655dc622 329 SMART SM00829 4 327 1.7E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS13810 87fbc91ab2e76b7a9364485b3891e704 272 Pfam PF11296 Protein of unknown function (DUF3097) 12 271 1.9E-124 T 28-03-2018 IPR021447 Protein of unknown function DUF3097 SMD44_RS13035 c5a61927dd2c30553bca13a9f4de45f6 434 Pfam PF07690 Major Facilitator Superfamily 10 362 2.8E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS13035 c5a61927dd2c30553bca13a9f4de45f6 434 SUPERFAMILY SSF103473 5 407 1.57E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS13035 c5a61927dd2c30553bca13a9f4de45f6 434 Gene3D G3DSA:1.20.1250.20 1 179 3.0E-19 T 28-03-2018 SMD44_RS13035 c5a61927dd2c30553bca13a9f4de45f6 434 Gene3D G3DSA:1.20.1250.20 222 421 8.3E-14 T 28-03-2018 SMD44_RS15555 95e8e675ea9050d1c7f1e44de18c512c 246 Pfam PF08044 Domain of unknown function (DUF1707) 28 80 2.0E-24 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 SMD44_RS21940 46f539d13e15fd77ea9938948127d5f6 497 Gene3D G3DSA:1.20.1250.20 14 204 3.3E-27 T 28-03-2018 SMD44_RS21940 46f539d13e15fd77ea9938948127d5f6 497 Gene3D G3DSA:1.20.1250.20 260 491 1.1E-19 T 28-03-2018 SMD44_RS21940 46f539d13e15fd77ea9938948127d5f6 497 Pfam PF07690 Major Facilitator Superfamily 28 421 1.5E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS21940 46f539d13e15fd77ea9938948127d5f6 497 SUPERFAMILY SSF103473 9 203 3.27E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS21940 46f539d13e15fd77ea9938948127d5f6 497 SUPERFAMILY SSF103473 256 475 3.27E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03485 7df408f461b31658e52978978c3749f9 262 SUPERFAMILY SSF46785 10 84 1.44E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03485 7df408f461b31658e52978978c3749f9 262 Pfam PF01614 Bacterial transcriptional regulator 129 249 3.7E-23 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS03485 7df408f461b31658e52978978c3749f9 262 Gene3D G3DSA:3.30.450.40 76 254 7.8E-39 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS03485 7df408f461b31658e52978978c3749f9 262 SUPERFAMILY SSF55781 82 250 1.96E-40 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS03485 7df408f461b31658e52978978c3749f9 262 Gene3D G3DSA:1.10.10.10 2 72 2.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03485 7df408f461b31658e52978978c3749f9 262 SMART SM00346 10 101 7.2E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS03485 7df408f461b31658e52978978c3749f9 262 Pfam PF09339 IclR helix-turn-helix domain 12 63 2.0E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS38950 a6acf888a3f4133e54b4b2f7e816ce9b 355 Gene3D G3DSA:3.40.50.1820 23 355 4.0E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38950 a6acf888a3f4133e54b4b2f7e816ce9b 355 SUPERFAMILY SSF53474 55 349 4.97E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38950 a6acf888a3f4133e54b4b2f7e816ce9b 355 Pfam PF00756 Putative esterase 67 346 3.9E-33 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 Gene3D G3DSA:1.20.120.530 69 215 1.7E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 Gene3D G3DSA:1.10.10.10 4 68 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 Pfam PF07729 FCD domain 76 197 4.9E-21 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 SMART SM00345 8 66 2.2E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 7.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 SUPERFAMILY SSF46785 7 95 5.96E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 SMART SM00895 76 198 3.3E-20 T 28-03-2018 IPR011711 GntR, C-terminal SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 7.7E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 7.7E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS31635 0cbc036aa03de170b8f2032a976b1c55 228 SUPERFAMILY SSF48008 72 201 1.36E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD44_RS16200 d16157aeb668936fab8c092df0976c96 180 Pfam PF07702 UTRA domain 33 170 3.2E-24 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS16200 d16157aeb668936fab8c092df0976c96 180 Gene3D G3DSA:3.40.1410.10 15 175 1.3E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS16200 d16157aeb668936fab8c092df0976c96 180 SMART SM00866 31 172 1.6E-21 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS16200 d16157aeb668936fab8c092df0976c96 180 SUPERFAMILY SSF64288 25 177 7.42E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS36030 8e74eb700f4acfab44d6d82e8715fd69 233 Gene3D G3DSA:3.40.50.970 26 231 1.3E-39 T 28-03-2018 SMD44_RS36030 8e74eb700f4acfab44d6d82e8715fd69 233 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 27 220 9.1E-27 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD44_RS36030 8e74eb700f4acfab44d6d82e8715fd69 233 SUPERFAMILY SSF52518 30 227 1.88E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS00355 9b02202d292bbc6fd69f7c2577f6cfd8 331 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD44_RS00355 9b02202d292bbc6fd69f7c2577f6cfd8 331 PIRSF PIRSF016838 67 233 6.8E-14 T 28-03-2018 IPR028349 Protein PafC SMD44_RS00355 9b02202d292bbc6fd69f7c2577f6cfd8 331 PIRSF PIRSF016838 253 325 29.0 T 28-03-2018 IPR028349 Protein PafC SMD44_RS00355 9b02202d292bbc6fd69f7c2577f6cfd8 331 PIRSF PIRSF016838 1 59 4.4E-4 T 28-03-2018 IPR028349 Protein PafC SMD44_RS00355 9b02202d292bbc6fd69f7c2577f6cfd8 331 Pfam PF13280 WYL domain 140 315 4.8E-27 T 28-03-2018 IPR026881 WYL domain SMD44_RS00355 9b02202d292bbc6fd69f7c2577f6cfd8 331 SUPERFAMILY SSF46785 4 64 1.23E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00355 9b02202d292bbc6fd69f7c2577f6cfd8 331 Gene3D G3DSA:1.10.10.10 1 65 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00355 9b02202d292bbc6fd69f7c2577f6cfd8 331 Pfam PF08279 HTH domain 7 62 1.3E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 Gene3D G3DSA:3.40.50.720 16 310 9.3E-62 T 28-03-2018 SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 235 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 153 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 85 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 254 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 206 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 273 293 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 76 307 8.2E-48 T 28-03-2018 SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 67 226 0.001 T 28-03-2018 SMD44_RS38320 599d12239690cbf60aa8a396e056e999 330 SUPERFAMILY SSF51735 66 307 1.53E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS15735 6be097874e7aa06307af11b107737c0e 159 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 4.8E-36 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD44_RS01440 dc68f080ab7a497378598d1f01185fea 124 Gene3D G3DSA:2.60.20.30 34 118 1.2E-5 T 28-03-2018 IPR015791 Antimicrobial/protein inhibitor, gamma-crystallin-like SMD44_RS01440 dc68f080ab7a497378598d1f01185fea 124 Pfam PF03995 Peptidase inhibitor family I36 31 104 2.3E-18 T 28-03-2018 SMD44_RS14695 8360cd682111483082da580bde79a147 907 SMART SM00382 625 805 7.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14695 8360cd682111483082da580bde79a147 907 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 430 531 5.9E-13 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD44_RS14695 8360cd682111483082da580bde79a147 907 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 97 289 1.9E-17 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMD44_RS14695 8360cd682111483082da580bde79a147 907 SUPERFAMILY SSF52540 589 821 2.4E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14695 8360cd682111483082da580bde79a147 907 Gene3D G3DSA:2.60.120.260 330 558 1.6E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS14695 8360cd682111483082da580bde79a147 907 SMART SM00939 319 548 1.1E-19 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD44_RS14695 8360cd682111483082da580bde79a147 907 Gene3D G3DSA:3.40.50.300 594 846 1.3E-62 T 28-03-2018 SMD44_RS14695 8360cd682111483082da580bde79a147 907 SUPERFAMILY SSF49785 361 548 5.53E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS14695 8360cd682111483082da580bde79a147 907 ProSitePatterns PS00211 ABC transporters family signature. 729 743 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS14695 8360cd682111483082da580bde79a147 907 Gene3D G3DSA:3.40.50.1820 52 329 4.8E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS14695 8360cd682111483082da580bde79a147 907 Pfam PF00005 ABC transporter 617 757 2.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS14695 8360cd682111483082da580bde79a147 907 SUPERFAMILY SSF53474 66 330 1.63E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 SUPERFAMILY SSF46785 2 112 1.56E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 Gene3D G3DSA:3.40.190.10 182 270 4.4E-21 T 28-03-2018 SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 Gene3D G3DSA:3.40.190.10 90 181 4.7E-24 T 28-03-2018 SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 SUPERFAMILY SSF53850 91 298 5.87E-34 T 28-03-2018 SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 Pfam PF03466 LysR substrate binding domain 90 295 1.4E-37 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 Gene3D G3DSA:1.10.10.10 2 84 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29735 f052b8639c54e152010b8f2ab7b4ad70 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.7E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS09600 78d74afd3d7654d3ea18fb2cd5f74e16 88 Pfam PF04149 Domain of unknown function (DUF397) 28 80 2.5E-18 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS03245 ea90edd0ef512fae47145bed73e454f8 379 Pfam PF07995 Glucose / Sorbosone dehydrogenase 50 367 3.6E-43 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMD44_RS03245 ea90edd0ef512fae47145bed73e454f8 379 SUPERFAMILY SSF50952 37 377 1.07E-28 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMD44_RS03245 ea90edd0ef512fae47145bed73e454f8 379 Gene3D G3DSA:2.120.10.30 23 379 3.1E-64 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS26860 b35970f35ca7abb36580961427fe07b9 258 SUPERFAMILY SSF88946 85 171 1.1E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26860 b35970f35ca7abb36580961427fe07b9 258 Pfam PF04542 Sigma-70 region 2 96 159 1.2E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26860 b35970f35ca7abb36580961427fe07b9 258 Gene3D G3DSA:1.10.1740.10 77 156 1.8E-15 T 28-03-2018 SMD44_RS26860 b35970f35ca7abb36580961427fe07b9 258 Gene3D G3DSA:1.10.10.10 157 241 1.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26860 b35970f35ca7abb36580961427fe07b9 258 SUPERFAMILY SSF88659 178 239 1.76E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26860 b35970f35ca7abb36580961427fe07b9 258 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 90 239 5.5E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS26860 b35970f35ca7abb36580961427fe07b9 258 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 85 241 1.3E-61 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD44_RS26860 b35970f35ca7abb36580961427fe07b9 258 Pfam PF08281 Sigma-70, region 4 186 237 2.5E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18945 84b63afca0e22b06fa5a2070d56289e9 293 SUPERFAMILY SSF52833 116 286 7.84E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS18945 84b63afca0e22b06fa5a2070d56289e9 293 Gene3D G3DSA:3.40.30.10 117 292 1.2E-38 T 28-03-2018 SMD44_RS18945 84b63afca0e22b06fa5a2070d56289e9 293 Pfam PF13462 Thioredoxin 119 274 2.3E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS26450 88fe2392674d3be89450458f62cc15f6 169 SUPERFAMILY SSF48317 3 162 5.49E-33 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS26450 88fe2392674d3be89450458f62cc15f6 169 Pfam PF01569 PAP2 superfamily 62 165 1.3E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS26450 88fe2392674d3be89450458f62cc15f6 169 SMART SM00014 57 160 1.1E-11 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS26450 88fe2392674d3be89450458f62cc15f6 169 Gene3D G3DSA:1.20.144.10 2 169 1.1E-32 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS15460 de43c269f5ded4a4e710a799a4b2d355 468 SUPERFAMILY SSF103473 256 465 3.92E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS15460 de43c269f5ded4a4e710a799a4b2d355 468 SUPERFAMILY SSF103473 14 209 3.92E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS15460 de43c269f5ded4a4e710a799a4b2d355 468 Gene3D G3DSA:1.20.1250.20 20 209 1.1E-20 T 28-03-2018 SMD44_RS15460 de43c269f5ded4a4e710a799a4b2d355 468 Gene3D G3DSA:1.20.1250.20 267 468 8.8E-25 T 28-03-2018 SMD44_RS15460 de43c269f5ded4a4e710a799a4b2d355 468 Pfam PF07690 Major Facilitator Superfamily 28 417 8.1E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS28120 d4962f47cfe2f83b265b3010b3d22543 167 SUPERFAMILY SSF55811 3 146 9.61E-23 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS28120 d4962f47cfe2f83b265b3010b3d22543 167 Gene3D G3DSA:3.90.79.10 1 148 2.3E-22 T 28-03-2018 SMD44_RS28120 d4962f47cfe2f83b265b3010b3d22543 167 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS28120 d4962f47cfe2f83b265b3010b3d22543 167 Pfam PF00293 NUDIX domain 7 135 5.3E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS37770 ea7c078d0e7293649d334276956d9a72 125 Gene3D G3DSA:1.10.10.10 13 113 1.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37770 ea7c078d0e7293649d334276956d9a72 125 SUPERFAMILY SSF46785 4 108 1.5E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37770 ea7c078d0e7293649d334276956d9a72 125 Pfam PF01638 HxlR-like helix-turn-helix 16 102 3.4E-30 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS17550 1194112028165dc5f9f0f1e9b580d97c 249 SMART SM01012 175 230 4.7E-16 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS17550 1194112028165dc5f9f0f1e9b580d97c 249 Gene3D G3DSA:3.30.450.40 1 187 7.4E-22 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS17550 1194112028165dc5f9f0f1e9b580d97c 249 Pfam PF03861 ANTAR domain 178 230 1.3E-15 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS17550 1194112028165dc5f9f0f1e9b580d97c 249 Gene3D G3DSA:1.10.10.10 188 231 9.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17550 1194112028165dc5f9f0f1e9b580d97c 249 SUPERFAMILY SSF52172 158 229 9.44E-7 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS17550 1194112028165dc5f9f0f1e9b580d97c 249 PIRSF PIRSF036625 1 238 5.2E-48 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS17550 1194112028165dc5f9f0f1e9b580d97c 249 SUPERFAMILY SSF55781 29 173 6.32E-18 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS17550 1194112028165dc5f9f0f1e9b580d97c 249 Pfam PF13185 GAF domain 29 162 5.1E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 Gene3D G3DSA:3.50.50.60 3 181 1.1E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 SUPERFAMILY SSF51905 3 340 4.37E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 8.5E-14 T 28-03-2018 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 8.5E-14 T 28-03-2018 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 8.5E-14 T 28-03-2018 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 Gene3D G3DSA:3.50.50.60 182 347 1.7E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 328 4.8E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.8E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 305 323 1.8E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS36410 6003691e52d0aad456ae413239462d0f 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 248 1.8E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS23440 97c2dd2339352ef8ade49f7d1cde2978 262 SUPERFAMILY SSF53474 11 259 2.3E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23440 97c2dd2339352ef8ade49f7d1cde2978 262 Pfam PF00561 alpha/beta hydrolase fold 31 133 4.1E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23440 97c2dd2339352ef8ade49f7d1cde2978 262 Gene3D G3DSA:3.40.50.1820 9 260 7.3E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS23440 97c2dd2339352ef8ade49f7d1cde2978 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 3.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23440 97c2dd2339352ef8ade49f7d1cde2978 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 3.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23440 97c2dd2339352ef8ade49f7d1cde2978 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 3.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS13555 7450d08a912e56501302777d91443fbb 138 Pfam PF01475 Ferric uptake regulator family 12 127 1.8E-31 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMD44_RS13555 7450d08a912e56501302777d91443fbb 138 Gene3D G3DSA:1.10.10.10 9 88 1.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13555 7450d08a912e56501302777d91443fbb 138 SUPERFAMILY SSF46785 12 133 4.16E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14335 fb3243dd30801af6db0e16da07075f50 168 PIRSF PIRSF034110 1 167 4.7E-43 T 28-03-2018 IPR009593 Protein of unknown function DUF1203 SMD44_RS14335 fb3243dd30801af6db0e16da07075f50 168 Pfam PF06718 Protein of unknown function (DUF1203) 37 166 1.5E-37 T 28-03-2018 IPR009593 Protein of unknown function DUF1203 SMD44_RS22985 dcf32f025484f5a65898c3d541ccf538 688 Pfam PF00391 PEP-utilising enzyme, mobile domain 610 672 1.3E-10 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS22985 dcf32f025484f5a65898c3d541ccf538 688 SUPERFAMILY SSF52009 601 673 3.14E-12 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS22985 dcf32f025484f5a65898c3d541ccf538 688 SUPERFAMILY SSF56059 18 293 2.0E-39 T 28-03-2018 SMD44_RS22985 dcf32f025484f5a65898c3d541ccf538 688 Gene3D G3DSA:3.50.30.10 550 687 8.3E-15 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD44_RS22985 dcf32f025484f5a65898c3d541ccf538 688 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 32 229 5.3E-24 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD44_RS22985 dcf32f025484f5a65898c3d541ccf538 688 Gene3D G3DSA:3.30.1490.20 14 191 1.7E-26 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS22985 dcf32f025484f5a65898c3d541ccf538 688 Gene3D G3DSA:3.30.470.20 192 290 2.0E-14 T 28-03-2018 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 Pfam PF00557 Metallopeptidase family M24 12 249 6.4E-43 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 5.4E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 5.4E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 5.4E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 5.4E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 Hamap MF_01974 Methionine aminopeptidase [map]. 2 258 37.692 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 SUPERFAMILY SSF55920 2 259 3.27E-73 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 Gene3D G3DSA:3.90.230.10 1 271 5.4E-69 T 28-03-2018 SMD44_RS25615 3fcead8ab76fc0d2b9fa376d69f4a17f 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 257 2.6E-80 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMD44_RS11285 631913113dd14d6553dd3c57a12d60a7 598 SUPERFAMILY SSF56801 17 288 6.8E-116 T 28-03-2018 SMD44_RS11285 631913113dd14d6553dd3c57a12d60a7 598 SUPERFAMILY SSF56801 337 596 6.8E-116 T 28-03-2018 SMD44_RS11285 631913113dd14d6553dd3c57a12d60a7 598 Gene3D G3DSA:3.40.50.980 13 188 6.8E-41 T 28-03-2018 SMD44_RS11285 631913113dd14d6553dd3c57a12d60a7 598 Pfam PF00501 AMP-binding enzyme 23 466 1.2E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS11285 631913113dd14d6553dd3c57a12d60a7 598 Gene3D G3DSA:3.40.50.980 189 387 2.6E-38 T 28-03-2018 SMD44_RS11285 631913113dd14d6553dd3c57a12d60a7 598 Gene3D G3DSA:2.30.38.10 388 459 2.2E-20 T 28-03-2018 SMD44_RS11285 631913113dd14d6553dd3c57a12d60a7 598 Gene3D G3DSA:3.30.300.30 461 598 8.8E-17 T 28-03-2018 SMD44_RS11285 631913113dd14d6553dd3c57a12d60a7 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS11880 69b5451e700a6d795e56578a0e687aff 210 Gene3D G3DSA:1.20.1260.10 39 207 2.5E-54 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS11880 69b5451e700a6d795e56578a0e687aff 210 Pfam PF03713 Domain of unknown function (DUF305) 47 203 1.3E-45 T 28-03-2018 IPR005183 Domain of unknown function DUF305 SMD44_RS30575 1b6bf973ad8e1d92aa64bff3f0617ad8 252 SUPERFAMILY SSF53633 15 245 2.09E-68 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMD44_RS30575 1b6bf973ad8e1d92aa64bff3f0617ad8 252 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 16 245 4.0E-91 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SMD44_RS30575 1b6bf973ad8e1d92aa64bff3f0617ad8 252 Gene3D G3DSA:3.40.1160.10 1 247 8.2E-39 T 28-03-2018 SMD44_RS30575 1b6bf973ad8e1d92aa64bff3f0617ad8 252 PIRSF PIRSF005650 11 252 2.6E-88 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 SMD44_RS30575 1b6bf973ad8e1d92aa64bff3f0617ad8 252 Hamap MF_01220_B Uridylate kinase [pyrH]. 12 246 42.73 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SMD44_RS30575 1b6bf973ad8e1d92aa64bff3f0617ad8 252 Pfam PF00696 Amino acid kinase family 16 224 2.8E-25 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMD44_RS05630 283c194d08817398e623909eee2ed13d 161 Gene3D G3DSA:3.90.960.10 1 161 2.7E-33 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS05630 283c194d08817398e623909eee2ed13d 161 Pfam PF04073 Aminoacyl-tRNA editing domain 31 150 4.1E-21 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS05630 283c194d08817398e623909eee2ed13d 161 SUPERFAMILY SSF55826 6 157 1.57E-30 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 8 343 62.225 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 Pfam PF00814 Glycoprotease family 30 317 3.1E-99 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 10 324 6.3E-127 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 Gene3D G3DSA:3.30.420.40 149 300 1.5E-18 T 28-03-2018 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 SUPERFAMILY SSF53067 9 319 5.4E-39 T 28-03-2018 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 ProSitePatterns PS01016 Glycoprotease family signature. 102 122 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 11 317 4.2E-99 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 Gene3D G3DSA:3.30.420.40 8 148 9.5E-37 T 28-03-2018 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 11 24 5.7E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 274 283 5.7E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 82 102 5.7E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 161 182 5.7E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 103 122 5.7E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25740 3b66c70be85bef70486e63d793127bc1 371 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 137 149 5.7E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25765 0e8b0a6f63e4f60afadbc5c0dd4771c1 335 SUPERFAMILY SSF88713 130 334 8.29E-41 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS25765 0e8b0a6f63e4f60afadbc5c0dd4771c1 335 Gene3D G3DSA:3.20.20.370 124 335 5.8E-39 T 28-03-2018 SMD44_RS25765 0e8b0a6f63e4f60afadbc5c0dd4771c1 335 Pfam PF01522 Polysaccharide deacetylase 149 268 5.3E-28 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS13200 eec3339f44c20df48cbad25746fd6eab 191 Pfam PF02342 TerD domain 1 187 1.9E-85 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS13200 eec3339f44c20df48cbad25746fd6eab 191 Gene3D G3DSA:2.60.60.30 19 186 9.7E-66 T 28-03-2018 SMD44_RS33670 fd04762f269240c9371cb42ab0fd4d63 248 Pfam PF01636 Phosphotransferase enzyme family 20 190 2.1E-18 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS33670 fd04762f269240c9371cb42ab0fd4d63 248 SUPERFAMILY SSF56112 11 221 2.33E-24 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS33670 fd04762f269240c9371cb42ab0fd4d63 248 Gene3D G3DSA:3.90.1200.10 71 222 2.1E-17 T 28-03-2018 SMD44_RS42775 8c1458105fa44a9f42c5aa2b8ef9aafd 474 Gene3D G3DSA:1.10.260.40 45 122 7.9E-8 T 28-03-2018 SMD44_RS42775 8c1458105fa44a9f42c5aa2b8ef9aafd 474 Gene3D G3DSA:1.25.40.10 207 447 1.7E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS33305 199f5beb070e88b95dc5220f405b9387 440 Pfam PF05977 Transmembrane secretion effector 4 400 9.2E-30 T 28-03-2018 IPR010290 Transmembrane secretion effector SMD44_RS33305 199f5beb070e88b95dc5220f405b9387 440 Gene3D G3DSA:1.20.1250.20 210 419 1.7E-15 T 28-03-2018 SMD44_RS33305 199f5beb070e88b95dc5220f405b9387 440 SUPERFAMILY SSF103473 10 401 9.81E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS33305 199f5beb070e88b95dc5220f405b9387 440 Gene3D G3DSA:1.20.1250.20 5 196 2.4E-18 T 28-03-2018 SMD44_RS29565 8a95a5384face2dd503847e701712dc2 413 Pfam PF03734 L,D-transpeptidase catalytic domain 259 364 8.5E-13 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD44_RS29565 8a95a5384face2dd503847e701712dc2 413 Gene3D G3DSA:2.60.40.10 55 152 2.7E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS29565 8a95a5384face2dd503847e701712dc2 413 SUPERFAMILY SSF141523 261 387 1.83E-23 T 28-03-2018 SMD44_RS29565 8a95a5384face2dd503847e701712dc2 413 Gene3D G3DSA:2.40.440.10 253 389 7.9E-27 T 28-03-2018 SMD44_RS38220 29d6d00cb8dc83050e28f2d7a2e2f7c5 537 SUPERFAMILY SSF51445 10 471 4.66E-113 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS38220 29d6d00cb8dc83050e28f2d7a2e2f7c5 537 Pfam PF00128 Alpha amylase, catalytic domain 36 384 3.0E-70 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS38220 29d6d00cb8dc83050e28f2d7a2e2f7c5 537 Pfam PF11941 Domain of unknown function (DUF3459) 458 535 3.8E-5 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMD44_RS38220 29d6d00cb8dc83050e28f2d7a2e2f7c5 537 SMART SM00642 21 412 3.3E-112 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS38220 29d6d00cb8dc83050e28f2d7a2e2f7c5 537 Gene3D G3DSA:3.20.20.80 11 475 2.8E-115 T 28-03-2018 SMD44_RS02810 e6db4b58531dcbca7266910be4495660 106 SUPERFAMILY SSF54292 20 99 2.71E-18 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS02810 e6db4b58531dcbca7266910be4495660 106 Gene3D G3DSA:3.10.20.30 17 98 4.8E-8 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS02810 e6db4b58531dcbca7266910be4495660 106 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 97 6.9E-25 T 28-03-2018 SMD44_RS07820 94079f770afab68f63d14408dd8452f4 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 245 265 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07820 94079f770afab68f63d14408dd8452f4 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07820 94079f770afab68f63d14408dd8452f4 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 225 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07820 94079f770afab68f63d14408dd8452f4 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 34 51 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS07820 94079f770afab68f63d14408dd8452f4 322 SUPERFAMILY SSF51735 30 281 1.33E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS07820 94079f770afab68f63d14408dd8452f4 322 Gene3D G3DSA:3.40.50.720 19 321 2.6E-57 T 28-03-2018 SMD44_RS07820 94079f770afab68f63d14408dd8452f4 322 Pfam PF00106 short chain dehydrogenase 34 162 1.5E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25730 077672aae63ff2d41d9007714a74bbf6 221 Gene3D G3DSA:3.30.420.40 1 138 3.2E-37 T 28-03-2018 SMD44_RS25730 077672aae63ff2d41d9007714a74bbf6 221 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 205 4.3E-57 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 SMD44_RS25730 077672aae63ff2d41d9007714a74bbf6 221 SUPERFAMILY SSF53067 111 203 7.51E-13 T 28-03-2018 SMD44_RS25730 077672aae63ff2d41d9007714a74bbf6 221 Pfam PF00814 Glycoprotease family 35 148 3.8E-31 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS25730 077672aae63ff2d41d9007714a74bbf6 221 SUPERFAMILY SSF53067 3 109 9.06E-23 T 28-03-2018 SMD44_RS34970 34aa52b62069c8627fd74ae179409635 289 SUPERFAMILY SSF56300 12 138 4.1E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS34970 34aa52b62069c8627fd74ae179409635 289 SUPERFAMILY SSF56300 178 264 4.1E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS34970 34aa52b62069c8627fd74ae179409635 289 Pfam PF00149 Calcineurin-like phosphoesterase 14 246 2.6E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS34970 34aa52b62069c8627fd74ae179409635 289 Gene3D G3DSA:3.60.21.10 11 268 1.5E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS34080 fa2d9e0f92f1c0d2eb781f2bf561fb9b 181 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 55 157 1.5E-25 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD44_RS07975 f442d711c27dc7fa323f675b74fb89dd 456 Gene3D G3DSA:3.40.309.10 246 433 1.6E-65 T 28-03-2018 SMD44_RS07975 f442d711c27dc7fa323f675b74fb89dd 456 SUPERFAMILY SSF53720 4 449 4.71E-157 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS07975 f442d711c27dc7fa323f675b74fb89dd 456 Pfam PF00171 Aldehyde dehydrogenase family 5 447 3.1E-162 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS07975 f442d711c27dc7fa323f675b74fb89dd 456 Gene3D G3DSA:3.40.605.10 3 245 4.8E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS07975 f442d711c27dc7fa323f675b74fb89dd 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS07975 f442d711c27dc7fa323f675b74fb89dd 456 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS29975 359d1dfa10feba9c3d655b236f8a55e4 449 Gene3D G3DSA:3.40.1130.10 62 277 3.0E-35 T 28-03-2018 SMD44_RS29975 359d1dfa10feba9c3d655b236f8a55e4 449 SUPERFAMILY SSF69593 86 250 3.92E-33 T 28-03-2018 SMD44_RS29975 359d1dfa10feba9c3d655b236f8a55e4 449 Pfam PF01553 Acyltransferase 92 210 1.9E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS29975 359d1dfa10feba9c3d655b236f8a55e4 449 SMART SM00563 97 213 4.5E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 Pfam PF03793 PASTA domain 380 441 3.0E-12 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 Pfam PF03793 PASTA domain 447 509 1.7E-13 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 Pfam PF03793 PASTA domain 516 576 7.1E-18 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 Pfam PF03793 PASTA domain 587 644 2.1E-7 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 SMART SM00220 11 277 3.0E-68 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 SUPERFAMILY SSF54184 511 572 3.27E-5 T 28-03-2018 SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 SMART SM00740 374 441 3.0E-12 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 SMART SM00740 442 509 2.6E-12 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 SMART SM00740 582 646 7.5E-5 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 SMART SM00740 510 576 9.6E-20 T 28-03-2018 IPR005543 PASTA domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 SUPERFAMILY SSF56112 7 273 1.15E-78 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 Pfam PF00069 Protein kinase domain 11 265 1.7E-52 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 Gene3D G3DSA:3.30.200.20 1 100 2.7E-24 T 28-03-2018 SMD44_RS21445 e4f40b60c376463d4ab72a1dd1c1d976 678 Gene3D G3DSA:1.10.510.10 101 537 8.9E-52 T 28-03-2018 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 SMART SM00421 148 210 2.5E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 Pfam PF00072 Response regulator receiver domain 3 108 3.9E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 SUPERFAMILY SSF52172 2 132 5.12E-16 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 Gene3D G3DSA:3.40.50.2300 1 131 1.7E-21 T 28-03-2018 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 SMART SM00448 1 120 7.0E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 Gene3D G3DSA:1.10.10.10 132 214 4.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 7.5E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23455 7c7e9e02046a9d634e270107085e4f0c 214 SUPERFAMILY SSF46894 137 201 9.86E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS20870 37ca316007e59de41a820f790b9a8032 71 ProDom PD267558 MEMBRANE TRANSMEMBRANE SPANNING SCO3924 1 31 8.0E-10 T 28-03-2018 IPR020246 Uncharacterised protein family SCO3924 SMD44_RS20870 37ca316007e59de41a820f790b9a8032 71 Pfam PF17260 Family of unknown function (DUF5326) 1 71 1.8E-36 T 28-03-2018 IPR020246 Uncharacterised protein family SCO3924 SMD44_RS16135 125468f80950df9c9a00964901d36303 542 Gene3D G3DSA:3.90.550.10 1 298 6.6E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16135 125468f80950df9c9a00964901d36303 542 SUPERFAMILY SSF53448 5 222 8.44E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16135 125468f80950df9c9a00964901d36303 542 Pfam PF00535 Glycosyl transferase family 2 9 133 1.9E-24 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS06825 1ec2c91b14939dfba6078d97a7d8d327 210 Gene3D G3DSA:3.30.1360.40 1 83 1.3E-16 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMD44_RS06825 1ec2c91b14939dfba6078d97a7d8d327 210 SUPERFAMILY SSF50891 87 208 7.21E-37 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS06825 1ec2c91b14939dfba6078d97a7d8d327 210 SMART SM00796 1 197 6.3E-69 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D SMD44_RS06825 1ec2c91b14939dfba6078d97a7d8d327 210 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 197 1.2E-54 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D SMD44_RS06825 1ec2c91b14939dfba6078d97a7d8d327 210 Gene3D G3DSA:2.40.100.10 85 210 4.7E-47 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS11545 4a9b5d203a4084d53993d0323a06caed 329 Pfam PF08279 HTH domain 5 60 2.5E-15 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 SMD44_RS11545 4a9b5d203a4084d53993d0323a06caed 329 PIRSF PIRSF016838 68 329 7.4E-8 T 28-03-2018 IPR028349 Protein PafC SMD44_RS11545 4a9b5d203a4084d53993d0323a06caed 329 PIRSF PIRSF016838 1 52 4.6E-4 T 28-03-2018 IPR028349 Protein PafC SMD44_RS11545 4a9b5d203a4084d53993d0323a06caed 329 Gene3D G3DSA:1.10.10.10 1 64 9.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11545 4a9b5d203a4084d53993d0323a06caed 329 SUPERFAMILY SSF46785 3 59 2.85E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11545 4a9b5d203a4084d53993d0323a06caed 329 Pfam PF13280 WYL domain 140 325 6.6E-41 T 28-03-2018 IPR026881 WYL domain SMD44_RS32730 81abe912a3c44be51187df5c2ed2490f 279 SUPERFAMILY SSF161098 5 278 6.45E-72 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS32730 81abe912a3c44be51187df5c2ed2490f 279 Gene3D G3DSA:1.10.3720.10 1 266 4.1E-50 T 28-03-2018 SMD44_RS32730 81abe912a3c44be51187df5c2ed2490f 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 268 1.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS00760 4e3c19a10ba4a5edb76c11cab696a436 142 SUPERFAMILY SSF54593 8 141 9.45E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS00760 4e3c19a10ba4a5edb76c11cab696a436 142 Gene3D G3DSA:3.10.180.10 1 141 5.5E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 Pfam PF07732 Multicopper oxidase 287 402 6.5E-36 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 SUPERFAMILY SSF49503 545 679 1.4E-33 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 SUPERFAMILY SSF49503 264 402 1.28E-36 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 ProSitePatterns PS00080 Multicopper oxidases signature 2. 664 675 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 Gene3D G3DSA:2.60.40.420 262 403 4.6E-37 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 Pfam PF07731 Multicopper oxidase 577 681 9.4E-27 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 Gene3D G3DSA:2.60.40.420 404 532 6.5E-12 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 SUPERFAMILY SSF49503 407 504 1.43E-7 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS00375 6c4e761b396204a00545bc425519ea87 699 Gene3D G3DSA:2.60.40.420 551 690 3.7E-34 T 28-03-2018 IPR008972 Cupredoxin SMD44_RS09540 8eb42548586b9228d047ba873da3bfa2 278 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 134 154 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD44_RS09540 8eb42548586b9228d047ba873da3bfa2 278 Pfam PF00378 Enoyl-CoA hydratase/isomerase 33 265 9.4E-39 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS09540 8eb42548586b9228d047ba873da3bfa2 278 SUPERFAMILY SSF52096 21 270 1.66E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS09540 8eb42548586b9228d047ba873da3bfa2 278 Gene3D G3DSA:3.90.226.10 12 274 4.8E-58 T 28-03-2018 SMD44_RS40335 be6f4f86a8861863971e611365ff302d 450 Pfam PF01547 Bacterial extracellular solute-binding protein 107 348 1.2E-23 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS40335 be6f4f86a8861863971e611365ff302d 450 Gene3D G3DSA:3.40.190.10 173 369 1.2E-31 T 28-03-2018 SMD44_RS40335 be6f4f86a8861863971e611365ff302d 450 SUPERFAMILY SSF53850 84 442 7.24E-45 T 28-03-2018 SMD44_RS40335 be6f4f86a8861863971e611365ff302d 450 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 167 184 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 SMD44_RS30790 57523f71865b863d3f1b429b6fc64bef 433 Pfam PF13180 PDZ domain 182 237 6.5E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS30790 57523f71865b863d3f1b429b6fc64bef 433 SUPERFAMILY SSF50156 128 237 3.29E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS30790 57523f71865b863d3f1b429b6fc64bef 433 Gene3D G3DSA:2.30.42.10 31 232 2.4E-13 T 28-03-2018 SMD44_RS30790 57523f71865b863d3f1b429b6fc64bef 433 Pfam PF02163 Peptidase family M50 13 386 9.7E-47 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 SMD44_RS13210 f7f1104c2215e011c1dfa301d8bfa33a 311 Gene3D G3DSA:3.30.2010.10 101 187 1.8E-20 T 28-03-2018 SMD44_RS13210 f7f1104c2215e011c1dfa301d8bfa33a 311 Pfam PF01435 Peptidase family M48 104 189 2.6E-14 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 Gene3D G3DSA:3.40.640.10 145 361 5.3E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 SUPERFAMILY SSF53383 119 480 1.22E-72 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 SUPERFAMILY SSF46785 30 101 8.36E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 2.1E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 2.1E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 Pfam PF00155 Aminotransferase class I and II 159 462 9.9E-30 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 Gene3D G3DSA:1.10.10.10 18 98 9.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 Gene3D G3DSA:3.90.1150.10 362 485 1.9E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 Pfam PF00392 Bacterial regulatory proteins, gntR family 35 94 4.3E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS06870 c986f125fa4da9938c195656a712c88d 501 SMART SM00345 38 97 6.1E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS37490 d1c405f28a7051868101b8c7042ddf91 377 Gene3D G3DSA:3.40.220.10 152 363 1.6E-15 T 28-03-2018 SMD44_RS37490 d1c405f28a7051868101b8c7042ddf91 377 PIRSF PIRSF014899 90 366 3.5E-120 T 28-03-2018 IPR012664 Conserved hypothetical protein CHP02452 SMD44_RS37490 d1c405f28a7051868101b8c7042ddf91 377 TIGRFAM TIGR02452 TIGR02452: TIGR02452 family protein 100 361 2.0E-95 T 28-03-2018 IPR012664 Conserved hypothetical protein CHP02452 SMD44_RS37490 d1c405f28a7051868101b8c7042ddf91 377 Pfam PF10021 Uncharacterized protein conserved in bacteria (DUF2263) 101 245 7.7E-55 T 28-03-2018 IPR019261 Domain of unknown function DUF2263 SMD44_RS11140 f9b7b5b0bc6c8efa779c035c78bbae38 306 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 27 299 7.5E-94 T 28-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SMD44_RS11140 f9b7b5b0bc6c8efa779c035c78bbae38 306 Pfam PF02219 Methylenetetrahydrofolate reductase 16 300 2.1E-107 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SMD44_RS11140 f9b7b5b0bc6c8efa779c035c78bbae38 306 SUPERFAMILY SSF51730 15 301 1.06E-91 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SMD44_RS11140 f9b7b5b0bc6c8efa779c035c78bbae38 306 Gene3D G3DSA:3.20.20.220 5 306 2.7E-96 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like SMD44_RS19895 f3bd3cbe7092b99cca6af86ef4c39e5e 292 Gene3D G3DSA:3.40.30.10 87 267 3.8E-43 T 28-03-2018 SMD44_RS19895 f3bd3cbe7092b99cca6af86ef4c39e5e 292 Pfam PF13462 Thioredoxin 98 262 1.4E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS19895 f3bd3cbe7092b99cca6af86ef4c39e5e 292 SUPERFAMILY SSF52833 88 261 1.52E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS18165 4332164a153ad0ecc822547b0f81f99a 263 SMART SM00382 36 232 8.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS18165 4332164a153ad0ecc822547b0f81f99a 263 SUPERFAMILY SSF52540 12 233 1.51E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS18165 4332164a153ad0ecc822547b0f81f99a 263 Pfam PF00005 ABC transporter 29 170 6.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS18165 4332164a153ad0ecc822547b0f81f99a 263 Gene3D G3DSA:3.40.50.300 2 246 3.1E-60 T 28-03-2018 SMD44_RS31205 ef5ea56e4be4fcfccc2f2c507c7399cf 413 Pfam PF01594 AI-2E family transporter 50 370 4.4E-76 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like SMD44_RS30025 4d6aadbcce26021e488ff70ef9a86887 239 Gene3D G3DSA:1.10.357.10 85 231 6.0E-19 T 28-03-2018 SMD44_RS30025 4d6aadbcce26021e488ff70ef9a86887 239 SUPERFAMILY SSF46689 31 104 2.64E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS30025 4d6aadbcce26021e488ff70ef9a86887 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 43 85 3.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30025 4d6aadbcce26021e488ff70ef9a86887 239 Gene3D G3DSA:1.10.10.60 31 84 3.1E-16 T 28-03-2018 SMD44_RS30025 4d6aadbcce26021e488ff70ef9a86887 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 56 8.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30025 4d6aadbcce26021e488ff70ef9a86887 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 64 87 8.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS43760 728379777a67d3ae08a94429fde075bc 200 Pfam PF00929 Exonuclease 10 165 3.2E-16 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS43760 728379777a67d3ae08a94429fde075bc 200 Gene3D G3DSA:1.20.5.140 150 170 5.1E-5 T 28-03-2018 SMD44_RS43760 728379777a67d3ae08a94429fde075bc 200 SMART SM00479 8 174 9.3E-27 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS43760 728379777a67d3ae08a94429fde075bc 200 Gene3D G3DSA:3.30.420.10 5 141 3.3E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS43760 728379777a67d3ae08a94429fde075bc 200 SUPERFAMILY SSF53098 6 177 7.09E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS08010 acc66970b4a5f773d4eb2c2272c8cf0a 265 Gene3D G3DSA:3.40.50.1980 105 255 1.7E-13 T 28-03-2018 SMD44_RS08010 acc66970b4a5f773d4eb2c2272c8cf0a 265 Gene3D G3DSA:3.40.50.1980 3 104 3.9E-17 T 28-03-2018 SMD44_RS08010 acc66970b4a5f773d4eb2c2272c8cf0a 265 SUPERFAMILY SSF53807 4 254 3.02E-30 T 28-03-2018 SMD44_RS11515 e9c463e42cc1ef7b7549c4a5eec2cbc7 264 Pfam PF02654 Cobalamin-5-phosphate synthase 13 255 2.0E-44 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS11515 e9c463e42cc1ef7b7549c4a5eec2cbc7 264 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 264 40.982 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 2.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 Pfam PF00072 Response regulator receiver domain 8 120 7.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 Gene3D G3DSA:1.10.10.10 138 225 5.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 SMART SM00421 163 220 1.6E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 1.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 1.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 1.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 SUPERFAMILY SSF52172 6 138 6.69E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 SUPERFAMILY SSF46894 153 226 2.14E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 SMART SM00448 6 119 2.9E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS33260 42e262273a999b6a75e96136c4c5223c 227 Gene3D G3DSA:3.40.50.2300 5 137 2.0E-38 T 28-03-2018 SMD44_RS25150 4e157b9ac2527d52d38dc2346465fbf7 334 Pfam PF12730 ABC-2 family transporter protein 120 259 1.1E-10 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS05250 bf4a9744caf18750ca8682ae3ca33d1a 194 Pfam PF00581 Rhodanese-like domain 17 102 6.1E-10 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05250 bf4a9744caf18750ca8682ae3ca33d1a 194 Gene3D G3DSA:3.40.250.10 2 116 1.4E-25 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05250 bf4a9744caf18750ca8682ae3ca33d1a 194 SUPERFAMILY SSF52821 7 110 1.26E-25 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05250 bf4a9744caf18750ca8682ae3ca33d1a 194 ProSitePatterns PS00380 Rhodanese signature 1. 35 46 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMD44_RS05250 bf4a9744caf18750ca8682ae3ca33d1a 194 SMART SM00450 10 107 2.6E-16 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS05250 bf4a9744caf18750ca8682ae3ca33d1a 194 Pfam PF11127 Protein of unknown function (DUF2892) 121 174 3.9E-11 T 28-03-2018 IPR021309 Protein of unknown function DUF2892 SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 31 444 2.4E-74 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 Gene3D G3DSA:1.20.1250.20 281 502 1.1E-24 T 28-03-2018 SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 Gene3D G3DSA:1.20.1250.20 20 219 2.9E-35 T 28-03-2018 SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 Pfam PF07690 Major Facilitator Superfamily 34 435 4.7E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 32 56 3.7E-7 T 28-03-2018 SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 153 177 3.7E-7 T 28-03-2018 SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 123 143 3.7E-7 T 28-03-2018 SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 SUPERFAMILY SSF103473 14 219 3.14E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17410 82ac722b288d74f7f0fc9e56d303019c 520 SUPERFAMILY SSF103473 270 492 3.14E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 SMART SM00422 1 69 7.8E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 Pfam PF13411 MerR HTH family regulatory protein 1 67 3.4E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 9.8E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 9.8E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 9.8E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 Gene3D G3DSA:1.10.1660.10 1 54 2.9E-17 T 28-03-2018 SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 Gene3D G3DSA:1.10.1660.10 55 114 6.4E-7 T 28-03-2018 SMD44_RS17540 73692dceeea61c8cdbbc0c853c7e1571 119 SUPERFAMILY SSF46955 1 110 3.37E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS36755 326a288f06fa44c71a654a9590bc50e2 221 SUPERFAMILY SSF52540 61 213 7.0E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS36755 326a288f06fa44c71a654a9590bc50e2 221 Gene3D G3DSA:3.40.50.300 70 220 5.0E-18 T 28-03-2018 SMD44_RS29005 03dd1558405ec91ce1923cd166366085 256 Pfam PF12679 ABC-2 family transporter protein 71 255 8.1E-7 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PIRSF PIRSF001480 1 383 4.1E-96 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 121 129 - T 28-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 SUPERFAMILY SSF51182 3 374 1.35E-94 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 Gene3D G3DSA:2.60.120.10 292 383 2.4E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PRINTS PR00714 Phosphomannose isomerase type I signature 76 97 6.6E-65 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PRINTS PR00714 Phosphomannose isomerase type I signature 216 231 6.6E-65 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PRINTS PR00714 Phosphomannose isomerase type I signature 121 144 6.6E-65 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PRINTS PR00714 Phosphomannose isomerase type I signature 251 270 6.6E-65 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 6.6E-65 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 6.6E-65 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PRINTS PR00714 Phosphomannose isomerase type I signature 232 251 6.6E-65 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 PRINTS PR00714 Phosphomannose isomerase type I signature 270 289 6.6E-65 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 Gene3D G3DSA:2.60.120.10 1 291 4.2E-77 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 Pfam PF01238 Phosphomannose isomerase type I 3 347 3.2E-74 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS16385 5c632507973dd864635156e73a7183a4 383 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 377 2.1E-73 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMD44_RS13120 a4bc5328db1276296ff57f1b4b1c0861 593 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 3 466 1.1E-43 T 28-03-2018 IPR013381 CRISPR-associated protein Cse1 SMD44_RS13120 a4bc5328db1276296ff57f1b4b1c0861 593 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 3 524 8.6E-93 T 28-03-2018 IPR013381 CRISPR-associated protein Cse1 SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 Gene3D G3DSA:3.40.50.2300 191 328 5.1E-48 T 28-03-2018 SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 SMART SM00354 13 83 2.0E-29 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 SUPERFAMILY SSF53822 73 350 2.94E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 Gene3D G3DSA:3.40.50.2300 67 190 4.9E-37 T 28-03-2018 SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 SUPERFAMILY SSF47413 13 71 2.07E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 Gene3D G3DSA:1.10.260.40 15 66 2.6E-22 T 28-03-2018 SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 Pfam PF13377 Periplasmic binding protein-like domain 184 351 1.8E-36 T 28-03-2018 SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 7.1E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS15045 361b65cba9fcba55cba25664e0d213ef 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 28-03-2018 SMD44_RS07735 04cab948b56b649c469f9ed93e61dc36 183 SUPERFAMILY SSF48498 87 176 1.37E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS07735 04cab948b56b649c469f9ed93e61dc36 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS07735 04cab948b56b649c469f9ed93e61dc36 183 SUPERFAMILY SSF46689 4 62 5.2E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS07735 04cab948b56b649c469f9ed93e61dc36 183 Gene3D G3DSA:1.10.357.10 44 180 1.9E-10 T 28-03-2018 SMD44_RS07735 04cab948b56b649c469f9ed93e61dc36 183 Gene3D G3DSA:1.10.10.60 2 43 2.5E-12 T 28-03-2018 SMD44_RS18350 a46895749315dec763aaf45caae7ea34 315 SUPERFAMILY SSF51735 1 276 1.82E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS18350 a46895749315dec763aaf45caae7ea34 315 Pfam PF08338 Domain of unknown function (DUF1731) 259 306 2.5E-8 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 SMD44_RS18350 a46895749315dec763aaf45caae7ea34 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 2.3E-12 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS18350 a46895749315dec763aaf45caae7ea34 315 Gene3D G3DSA:3.40.50.720 1 313 1.9E-29 T 28-03-2018 SMD44_RS18350 a46895749315dec763aaf45caae7ea34 315 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 297 5.1E-64 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 SMD44_RS05080 c229e0735d5614193a18ef7b26501896 329 Pfam PF16169 Domain of unknown function (DUF4872) 155 324 1.9E-52 T 28-03-2018 IPR032369 Domain of unknown function DUF4872 SMD44_RS05080 c229e0735d5614193a18ef7b26501896 329 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 14 142 3.9E-46 T 28-03-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 SMD44_RS05080 c229e0735d5614193a18ef7b26501896 329 Gene3D G3DSA:3.90.70.10 10 180 7.8E-10 T 28-03-2018 SMD44_RS05375 5736c072658bde21b2009bc0cbeffa52 302 SUPERFAMILY SSF53335 41 89 8.94E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS05375 5736c072658bde21b2009bc0cbeffa52 302 SUPERFAMILY SSF53335 125 237 8.94E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS05375 5736c072658bde21b2009bc0cbeffa52 302 Gene3D G3DSA:3.40.50.150 9 281 1.3E-6 T 28-03-2018 SMD44_RS10365 33f51ca56a19c50b404da52628aeffe4 320 SUPERFAMILY SSF56219 3 318 1.8E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS10365 33f51ca56a19c50b404da52628aeffe4 320 Gene3D G3DSA:3.60.10.10 1 319 1.8E-24 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS10365 33f51ca56a19c50b404da52628aeffe4 320 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 311 2.0E-9 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS23265 2e49b116f79d06527ae83afbe02c68b3 389 Gene3D G3DSA:3.40.50.300 168 351 3.2E-12 T 28-03-2018 SMD44_RS23265 2e49b116f79d06527ae83afbe02c68b3 389 SUPERFAMILY SSF52540 48 356 4.78E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23265 2e49b116f79d06527ae83afbe02c68b3 389 Pfam PF00437 Type II/IV secretion system protein 60 334 1.6E-78 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMD44_RS23265 2e49b116f79d06527ae83afbe02c68b3 389 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 10 346 5.2E-158 T 28-03-2018 IPR022399 Helicase/secretion neighbourhood ATPase SMD44_RS23265 2e49b116f79d06527ae83afbe02c68b3 389 Gene3D G3DSA:3.30.450.90 56 160 8.0E-38 T 28-03-2018 SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 Pfam PF08281 Sigma-70, region 4 102 153 6.7E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 Gene3D G3DSA:1.10.10.10 69 155 3.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 SUPERFAMILY SSF54427 166 282 2.01E-16 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 SUPERFAMILY SSF88659 92 159 2.62E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 SUPERFAMILY SSF88946 5 83 8.63E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 Gene3D G3DSA:1.10.1740.10 2 68 6.6E-14 T 28-03-2018 SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 154 6.7E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 Pfam PF04542 Sigma-70 region 2 6 69 1.6E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 5 281 5.7E-103 T 28-03-2018 IPR014303 RNA polymerase sigma-70, ECF type SMD44_RS38530 9ac7a4e726f0a9250e1eca25d1f364e4 298 Gene3D G3DSA:3.10.450.50 156 286 2.2E-19 T 28-03-2018 SMD44_RS08045 be61f6e303bed8140525d77306e4f8d7 319 Gene3D G3DSA:3.30.2350.10 94 299 7.0E-46 T 28-03-2018 SMD44_RS08045 be61f6e303bed8140525d77306e4f8d7 319 Pfam PF00849 RNA pseudouridylate synthase 102 250 1.5E-16 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS08045 be61f6e303bed8140525d77306e4f8d7 319 SUPERFAMILY SSF55120 86 300 8.64E-50 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS08045 be61f6e303bed8140525d77306e4f8d7 319 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 141 155 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS01735 e42a535014925ae8039126d7f31b5d0e 142 SUPERFAMILY SSF54427 9 124 3.26E-14 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS01735 e42a535014925ae8039126d7f31b5d0e 142 Gene3D G3DSA:3.10.450.50 5 137 6.5E-17 T 28-03-2018 SMD44_RS01735 e42a535014925ae8039126d7f31b5d0e 142 Pfam PF12680 SnoaL-like domain 28 121 1.2E-9 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS16920 193084d63ba0edf48e09b570bb23ae65 162 Pfam PF14433 SUKH-3 immunity protein 9 153 1.7E-47 T 28-03-2018 IPR025850 SUKH-3 immunity protein SMD44_RS08320 9e9e19b64cc156b30474685eaf849d6f 262 Gene3D G3DSA:1.20.1260.10 17 213 4.3E-22 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS08320 9e9e19b64cc156b30474685eaf849d6f 262 SUPERFAMILY SSF47240 15 170 7.77E-10 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS36430 b6288bd57415491b74b5aff4e05e6113 354 Gene3D G3DSA:3.20.20.70 81 338 6.7E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS36430 b6288bd57415491b74b5aff4e05e6113 354 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 88 333 6.6E-105 T 28-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD44_RS36430 b6288bd57415491b74b5aff4e05e6113 354 Pfam PF00793 DAHP synthetase I family 98 326 9.7E-63 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 SMD44_RS36430 b6288bd57415491b74b5aff4e05e6113 354 SUPERFAMILY SSF51569 12 334 3.21E-82 T 28-03-2018 SMD44_RS17290 0fb773925132138089b4979c66611b7f 183 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 82 95 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 SMD44_RS17290 0fb773925132138089b4979c66611b7f 183 Pfam PF00994 Probable molybdopterin binding domain 25 163 4.2E-28 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17290 0fb773925132138089b4979c66611b7f 183 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 21 160 9.0E-31 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17290 0fb773925132138089b4979c66611b7f 183 SMART SM00852 24 166 2.8E-20 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17290 0fb773925132138089b4979c66611b7f 183 SUPERFAMILY SSF53218 21 171 7.07E-41 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17290 0fb773925132138089b4979c66611b7f 183 Gene3D G3DSA:3.40.980.10 18 177 1.0E-36 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS21475 0b90a92d2e61a4a9ad9a9584cda11dc9 297 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 213 294 1.9E-14 T 28-03-2018 IPR032030 YscD, cytoplasmic domain SMD44_RS21475 0b90a92d2e61a4a9ad9a9584cda11dc9 297 SMART SM00240 223 272 4.7E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS21475 0b90a92d2e61a4a9ad9a9584cda11dc9 297 SUPERFAMILY SSF49879 181 293 2.49E-22 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS21475 0b90a92d2e61a4a9ad9a9584cda11dc9 297 Gene3D G3DSA:2.60.200.20 83 295 2.2E-21 T 28-03-2018 SMD44_RS21475 0b90a92d2e61a4a9ad9a9584cda11dc9 297 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 1.2E-41 T 28-03-2018 IPR022128 Domain of unknown function DUF3662 SMD44_RS24365 b4c969bbcc4d5a13d3a8e492a76c40c3 240 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 13 219 3.2E-50 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 SMD44_RS24365 b4c969bbcc4d5a13d3a8e492a76c40c3 240 Gene3D G3DSA:1.20.1250.20 5 230 2.1E-5 T 28-03-2018 SMD44_RS11010 a877ee586d63e1a6d937c2f2c5ff7e9d 241 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 14 239 1.7E-70 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase SMD44_RS11010 a877ee586d63e1a6d937c2f2c5ff7e9d 241 Gene3D G3DSA:3.60.140.10 1 241 6.2E-84 T 28-03-2018 SMD44_RS11010 a877ee586d63e1a6d937c2f2c5ff7e9d 241 SUPERFAMILY SSF64438 5 241 1.21E-73 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic SMD44_RS11010 a877ee586d63e1a6d937c2f2c5ff7e9d 241 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 19 240 1.2E-46 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase SMD44_RS34730 bfc55532174281362712f81e9f5b45f3 334 SUPERFAMILY SSF51658 9 317 7.73E-56 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS34730 bfc55532174281362712f81e9f5b45f3 334 Pfam PF01261 Xylose isomerase-like TIM barrel 23 259 8.5E-37 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS34730 bfc55532174281362712f81e9f5b45f3 334 Gene3D G3DSA:3.20.20.150 1 320 1.9E-58 T 28-03-2018 SMD44_RS34730 bfc55532174281362712f81e9f5b45f3 334 Pfam PF07582 AP endonuclease family 2 C terminus 275 329 6.0E-24 T 28-03-2018 IPR011418 AP endonuclease, family 2, C-terminal SMD44_RS16545 bbe21c437ce33f65564bef659454b050 180 Gene3D G3DSA:3.40.50.7700 2 165 4.2E-74 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD44_RS16545 bbe21c437ce33f65564bef659454b050 180 PIRSF PIRSF001338 5 167 7.9E-70 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 SMD44_RS16545 bbe21c437ce33f65564bef659454b050 180 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 9 160 33.022 T 28-03-2018 IPR033747 Class I PurE SMD44_RS16545 bbe21c437ce33f65564bef659454b050 180 Pfam PF00731 AIR carboxylase 9 154 2.5E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD44_RS16545 bbe21c437ce33f65564bef659454b050 180 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 9 163 2.1E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD44_RS16545 bbe21c437ce33f65564bef659454b050 180 SUPERFAMILY SSF52255 7 165 2.49E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD44_RS16545 bbe21c437ce33f65564bef659454b050 180 SMART SM01001 7 156 4.1E-99 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD44_RS42610 787e75fdaef0efdef4bab02a1db80eda 365 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 217 343 3.3E-8 T 28-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal SMD44_RS42610 787e75fdaef0efdef4bab02a1db80eda 365 SUPERFAMILY SSF53901 193 347 3.22E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS42610 787e75fdaef0efdef4bab02a1db80eda 365 PIRSF PIRSF000451 2 354 4.1E-80 T 28-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 SMD44_RS42610 787e75fdaef0efdef4bab02a1db80eda 365 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 66 205 5.9E-20 T 28-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal SMD44_RS42610 787e75fdaef0efdef4bab02a1db80eda 365 Gene3D G3DSA:3.40.47.10 3 207 3.5E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS42610 787e75fdaef0efdef4bab02a1db80eda 365 Gene3D G3DSA:3.40.47.10 213 348 4.7E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS42610 787e75fdaef0efdef4bab02a1db80eda 365 SUPERFAMILY SSF53901 3 205 7.04E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 SUPERFAMILY SSF48208 189 538 8.16E-71 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 SUPERFAMILY SSF52833 1 127 1.19E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 Pfam PF03190 Protein of unknown function, DUF255 3 163 1.7E-74 T 28-03-2018 IPR004879 Domain of unknown function DUF255 SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 478 517 0.071 T 28-03-2018 SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 219 314 0.29 T 28-03-2018 SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 Gene3D G3DSA:1.50.10.10 344 605 5.8E-26 T 28-03-2018 SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 Gene3D G3DSA:1.50.10.10 212 343 7.2E-27 T 28-03-2018 SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 Gene3D G3DSA:3.40.30.10 1 171 6.7E-31 T 28-03-2018 SMD44_RS27185 b1ad0cf3b4b1468978d0b3ed6e22115d 675 PIRSF PIRSF006402 1 674 1.6E-205 T 28-03-2018 IPR024705 Spermatogenesis-associated protein 20 SMD44_RS38185 bbfd3fd503a40f4cebd6c0f0f2653dbe 441 Gene3D G3DSA:3.90.1150.10 305 430 2.4E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS38185 bbfd3fd503a40f4cebd6c0f0f2653dbe 441 SUPERFAMILY SSF53383 45 427 1.39E-49 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS38185 bbfd3fd503a40f4cebd6c0f0f2653dbe 441 Gene3D G3DSA:3.40.640.10 72 304 5.0E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS38185 bbfd3fd503a40f4cebd6c0f0f2653dbe 441 Pfam PF12897 Alanine-glyoxylate amino-transferase 29 436 4.4E-174 T 28-03-2018 IPR024551 Aminotransferase, putative SMD44_RS21820 144d9d5185d14c7a6e02cef0c3af16e3 326 Gene3D G3DSA:3.40.50.920 196 325 1.1E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS21820 144d9d5185d14c7a6e02cef0c3af16e3 326 Pfam PF02780 Transketolase, C-terminal domain 196 315 2.6E-40 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SMD44_RS21820 144d9d5185d14c7a6e02cef0c3af16e3 326 Pfam PF02779 Transketolase, pyrimidine binding domain 5 179 6.5E-47 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS21820 144d9d5185d14c7a6e02cef0c3af16e3 326 Gene3D G3DSA:3.40.50.970 2 195 8.4E-60 T 28-03-2018 SMD44_RS21820 144d9d5185d14c7a6e02cef0c3af16e3 326 SUPERFAMILY SSF52518 5 188 1.03E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS21820 144d9d5185d14c7a6e02cef0c3af16e3 326 SMART SM00861 6 181 1.4E-68 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS21820 144d9d5185d14c7a6e02cef0c3af16e3 326 SUPERFAMILY SSF52922 193 324 3.66E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS11495 4dd0feaef6d1219d6289d1a01fa40a19 401 Gene3D G3DSA:1.10.1610.10 7 72 1.8E-19 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS11495 4dd0feaef6d1219d6289d1a01fa40a19 401 Gene3D G3DSA:3.40.50.10210 73 335 1.6E-85 T 28-03-2018 SMD44_RS11495 4dd0feaef6d1219d6289d1a01fa40a19 401 SUPERFAMILY SSF52733 7 344 2.22E-88 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS11495 4dd0feaef6d1219d6289d1a01fa40a19 401 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 15 354 31.364 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS11495 4dd0feaef6d1219d6289d1a01fa40a19 401 Pfam PF02277 Phosphoribosyltransferase 13 344 1.8E-100 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS11495 4dd0feaef6d1219d6289d1a01fa40a19 401 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 17 345 5.3E-100 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD44_RS13030 c4eb4159f5eefd981216f9ce8ed659fe 295 Gene3D G3DSA:3.60.130.10 44 289 4.1E-17 T 28-03-2018 SMD44_RS13030 c4eb4159f5eefd981216f9ce8ed659fe 295 SUPERFAMILY SSF51197 56 287 5.04E-17 T 28-03-2018 SMD44_RS13030 c4eb4159f5eefd981216f9ce8ed659fe 295 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 65 284 1.7E-10 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD44_RS01225 ba24ebebfaac2f152182085cfecd59cc 687 SUPERFAMILY SSF48452 416 557 1.58E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS01225 ba24ebebfaac2f152182085cfecd59cc 687 SUPERFAMILY SSF52540 26 229 1.95E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS01225 ba24ebebfaac2f152182085cfecd59cc 687 Pfam PF00931 NB-ARC domain 17 203 1.6E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS01225 ba24ebebfaac2f152182085cfecd59cc 687 Gene3D G3DSA:3.40.50.300 3 154 7.5E-7 T 28-03-2018 SMD44_RS01225 ba24ebebfaac2f152182085cfecd59cc 687 Pfam PF13424 Tetratricopeptide repeat 494 561 1.8E-7 T 28-03-2018 SMD44_RS01225 ba24ebebfaac2f152182085cfecd59cc 687 Gene3D G3DSA:1.10.10.10 553 645 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01225 ba24ebebfaac2f152182085cfecd59cc 687 Gene3D G3DSA:1.10.10.10 468 552 1.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01225 ba24ebebfaac2f152182085cfecd59cc 687 SUPERFAMILY SSF48452 532 650 1.39E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS29885 815503c1ea1015ed2826454e5978c9ea 391 Gene3D G3DSA:2.120.10.30 49 304 1.6E-57 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS29885 815503c1ea1015ed2826454e5978c9ea 391 Gene3D G3DSA:2.120.10.30 305 387 0.0067 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS29885 815503c1ea1015ed2826454e5978c9ea 391 Pfam PF07995 Glucose / Sorbosone dehydrogenase 74 374 3.3E-74 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMD44_RS29885 815503c1ea1015ed2826454e5978c9ea 391 SUPERFAMILY SSF50952 64 374 3.27E-45 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMD44_RS19425 9a5dec43c0d846c46da9820f0ff7b7ef 528 SUPERFAMILY SSF56176 69 261 1.12E-52 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS19425 9a5dec43c0d846c46da9820f0ff7b7ef 528 Gene3D G3DSA:3.30.465.10 150 287 1.5E-40 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS19425 9a5dec43c0d846c46da9820f0ff7b7ef 528 Pfam PF08031 Berberine and berberine like 485 527 9.6E-13 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMD44_RS19425 9a5dec43c0d846c46da9820f0ff7b7ef 528 Pfam PF01565 FAD binding domain 96 228 4.5E-31 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD44_RS19425 9a5dec43c0d846c46da9820f0ff7b7ef 528 Gene3D G3DSA:3.30.43.10 70 149 6.4E-19 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD44_RS03420 4736a5c9e53e6e9956b26cffcb512eb5 349 SUPERFAMILY SSF51445 38 347 2.63E-74 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS03420 4736a5c9e53e6e9956b26cffcb512eb5 349 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 170 179 - T 28-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 SMD44_RS03420 4736a5c9e53e6e9956b26cffcb512eb5 349 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 57 308 9.1E-46 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 SMD44_RS03420 4736a5c9e53e6e9956b26cffcb512eb5 349 Gene3D G3DSA:3.20.20.80 38 346 4.2E-48 T 28-03-2018 SMD44_RS10235 4d63c9acd3dba8a63d026bf3f926aa12 664 Gene3D G3DSA:2.60.60.30 28 163 1.7E-19 T 28-03-2018 SMD44_RS10235 4d63c9acd3dba8a63d026bf3f926aa12 664 Pfam PF02342 TerD domain 64 162 6.8E-16 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 SUPERFAMILY SSF50249 1 66 3.05E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 PIRSF PIRSF002599 1 67 2.2E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 PRINTS PR00050 Cold shock protein signature 25 34 5.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 PRINTS PR00050 Cold shock protein signature 4 19 5.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 PRINTS PR00050 Cold shock protein signature 40 58 5.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 SMART SM00357 3 67 7.7E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.5E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS10650 e6b815e9f0b53427200687536154cfa3 67 Gene3D G3DSA:2.40.50.140 1 67 3.2E-28 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 Pfam PF11870 Domain of unknown function (DUF3390) 393 484 1.4E-14 T 28-03-2018 IPR024569 4Fe-4S binding protein, C-terminal SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 Pfam PF02589 LUD domain 73 298 1.3E-46 T 28-03-2018 IPR003741 LUD domain SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 Gene3D G3DSA:3.30.70.20 307 326 0.031 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 SUPERFAMILY SSF100950 136 300 7.53E-34 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 SUPERFAMILY SSF100950 66 90 7.53E-34 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 Pfam PF13183 4Fe-4S dicluster domain 315 384 1.0E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 SUPERFAMILY SSF54862 296 398 7.95E-15 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 Gene3D G3DSA:3.30.70.20 327 378 2.1E-9 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 Gene3D G3DSA:3.40.50.10420 144 300 6.8E-39 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 Gene3D G3DSA:3.40.50.10420 66 143 5.7E-10 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 Gene3D G3DSA:3.30.70.20 379 406 0.38 T 28-03-2018 SMD44_RS38295 b60140583d497bfe360d4d71a7c123fb 519 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 318 329 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS23200 4d3988e87338bc0411bcb7131eb19d9a 400 Gene3D G3DSA:2.40.10.10 182 278 2.3E-16 T 28-03-2018 SMD44_RS23200 4d3988e87338bc0411bcb7131eb19d9a 400 Pfam PF13365 Trypsin-like peptidase domain 221 359 4.4E-22 T 28-03-2018 SMD44_RS23200 4d3988e87338bc0411bcb7131eb19d9a 400 PRINTS PR00834 HtrA/DegQ protease family signature 330 347 6.9E-7 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS23200 4d3988e87338bc0411bcb7131eb19d9a 400 PRINTS PR00834 HtrA/DegQ protease family signature 251 271 6.9E-7 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS23200 4d3988e87338bc0411bcb7131eb19d9a 400 PRINTS PR00834 HtrA/DegQ protease family signature 229 241 6.9E-7 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS23200 4d3988e87338bc0411bcb7131eb19d9a 400 SUPERFAMILY SSF50494 196 384 1.82E-36 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS23200 4d3988e87338bc0411bcb7131eb19d9a 400 Pfam PF02674 Colicin V production protein 4 148 8.3E-21 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 SMD44_RS23200 4d3988e87338bc0411bcb7131eb19d9a 400 Gene3D G3DSA:2.40.10.10 279 385 1.3E-18 T 28-03-2018 SMD44_RS19100 d2e6fbe1b05d0dad500e964c8a111496 204 Gene3D G3DSA:1.20.120.20 3 184 6.8E-4 T 28-03-2018 SMD44_RS27155 baa8db00356e74847adef9550e2897db 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 290 51.648 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 SMD44_RS27155 baa8db00356e74847adef9550e2897db 293 Gene3D G3DSA:3.40.50.10320 1 293 1.5E-67 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS27155 baa8db00356e74847adef9550e2897db 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 289 1.3E-148 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 SMD44_RS27155 baa8db00356e74847adef9550e2897db 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 154 1.1E-25 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD44_RS27155 baa8db00356e74847adef9550e2897db 293 SUPERFAMILY SSF102588 4 291 2.09E-70 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS00280 83201cc349c0fab33f0500f50707ef42 306 ProSitePatterns PS00770 Aminotransferases class-IV signature. 193 222 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS00280 83201cc349c0fab33f0500f50707ef42 306 Gene3D G3DSA:3.30.470.10 1 141 2.4E-39 T 28-03-2018 SMD44_RS00280 83201cc349c0fab33f0500f50707ef42 306 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 10 305 4.6E-118 T 28-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 SMD44_RS00280 83201cc349c0fab33f0500f50707ef42 306 SUPERFAMILY SSF56752 7 303 4.58E-100 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS00280 83201cc349c0fab33f0500f50707ef42 306 Pfam PF01063 Amino-transferase class IV 35 267 5.5E-49 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD44_RS00280 83201cc349c0fab33f0500f50707ef42 306 Gene3D G3DSA:3.20.10.10 142 302 1.3E-51 T 28-03-2018 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 SUPERFAMILY SSF50494 36 261 6.2E-61 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 208 219 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 Pfam PF00089 Trypsin 43 255 1.6E-49 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 Gene3D G3DSA:2.40.10.10 43 70 4.3E-13 T 28-03-2018 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 75 80 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 65 80 1.3E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 120 134 1.3E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 207 219 1.3E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 Gene3D G3DSA:2.40.10.10 71 128 2.2E-14 T 28-03-2018 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 Gene3D G3DSA:2.40.10.10 129 264 1.7E-38 T 28-03-2018 SMD44_RS10635 9d0dbdfc2566ab7df4ea548ac6e7b667 265 SMART SM00020 42 258 1.1E-63 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS36995 10354cc9aa2610fb1f42f9adfc9517f7 146 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 141 4.7E-31 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD44_RS36995 10354cc9aa2610fb1f42f9adfc9517f7 146 Gene3D G3DSA:2.30.110.10 7 144 2.7E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS36995 10354cc9aa2610fb1f42f9adfc9517f7 146 Pfam PF04075 F420H(2)-dependent quinone reductase 15 139 1.5E-40 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD44_RS06275 37e25a22c6e6f40a8e68df1b3471a5fa 184 Gene3D G3DSA:2.160.10.10 4 179 1.7E-40 T 28-03-2018 SMD44_RS06275 37e25a22c6e6f40a8e68df1b3471a5fa 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 125 4.1E-7 T 28-03-2018 IPR001451 Hexapeptide repeat SMD44_RS06275 37e25a22c6e6f40a8e68df1b3471a5fa 184 SUPERFAMILY SSF51161 11 172 1.8E-46 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS12935 dcdecddf64a3511747044638f0e9a964 232 Pfam PF13489 Methyltransferase domain 51 198 9.9E-15 T 28-03-2018 SMD44_RS12935 dcdecddf64a3511747044638f0e9a964 232 Gene3D G3DSA:3.40.50.150 43 228 4.1E-27 T 28-03-2018 SMD44_RS12935 dcdecddf64a3511747044638f0e9a964 232 SUPERFAMILY SSF53335 49 207 1.27E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 Gene3D G3DSA:3.40.50.300 554 804 2.5E-13 T 28-03-2018 SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 16 215 9.7E-25 T 28-03-2018 IPR006483 CRISPR-associated Cas3-HD domain SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 SMART SM00487 270 519 0.0052 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 Gene3D G3DSA:3.40.50.300 261 500 2.1E-12 T 28-03-2018 SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 Gene3D G3DSA:1.10.3210.10 17 214 0.0018 T 28-03-2018 SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 SUPERFAMILY SSF52540 545 693 2.48E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 SUPERFAMILY SSF52540 293 345 2.48E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 SUPERFAMILY SSF52540 415 487 2.48E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43560 4d63e2c937455e0b76fd2082981f1cf6 947 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 296 695 1.1E-45 T 28-03-2018 IPR006474 Helicase Cas3, CRISPR-associated, core SMD44_RS03155 9940707bc5b9f1e727b5df7ce72ea542 440 Gene3D G3DSA:1.20.1250.20 50 232 3.4E-13 T 28-03-2018 SMD44_RS03155 9940707bc5b9f1e727b5df7ce72ea542 440 Pfam PF07690 Major Facilitator Superfamily 54 395 1.6E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS03155 9940707bc5b9f1e727b5df7ce72ea542 440 SUPERFAMILY SSF103473 52 433 4.58E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03155 9940707bc5b9f1e727b5df7ce72ea542 440 Gene3D G3DSA:1.20.1250.20 237 437 7.7E-8 T 28-03-2018 SMD44_RS33095 7c35df73ead7178938ce4f1e47488f9f 239 Gene3D G3DSA:3.10.350.10 179 237 6.4E-12 T 28-03-2018 SMD44_RS33095 7c35df73ead7178938ce4f1e47488f9f 239 Pfam PF01476 LysM domain 186 232 2.1E-7 T 28-03-2018 IPR018392 LysM domain SMD44_RS33095 7c35df73ead7178938ce4f1e47488f9f 239 SUPERFAMILY SSF54106 184 232 9.81E-5 T 28-03-2018 IPR018392 LysM domain SMD44_RS33095 7c35df73ead7178938ce4f1e47488f9f 239 SMART SM00257 185 232 2.2E-4 T 28-03-2018 IPR018392 LysM domain SMD44_RS23890 2a7438f2406c81ac0e26699005e335fc 488 SUPERFAMILY SSF52777 63 214 9.56E-18 T 28-03-2018 SMD44_RS23890 2a7438f2406c81ac0e26699005e335fc 488 SUPERFAMILY SSF52777 230 464 9.67E-15 T 28-03-2018 SMD44_RS23890 2a7438f2406c81ac0e26699005e335fc 488 Pfam PF00668 Condensation domain 67 368 4.9E-16 T 28-03-2018 IPR001242 Condensation domain SMD44_RS23890 2a7438f2406c81ac0e26699005e335fc 488 Gene3D G3DSA:3.30.559.10 35 224 3.5E-13 T 28-03-2018 SMD44_RS04010 098f2288b6c0be14471c6105f82ac06d 170 Pfam PF13581 Histidine kinase-like ATPase domain 14 127 1.1E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04010 098f2288b6c0be14471c6105f82ac06d 170 SUPERFAMILY SSF55874 24 128 2.81E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04010 098f2288b6c0be14471c6105f82ac06d 170 Gene3D G3DSA:3.30.565.10 4 137 1.3E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42305 1506f41c91f6fb557056be188e70bf6e 331 Pfam PF01068 ATP dependent DNA ligase domain 9 200 2.5E-23 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMD44_RS42305 1506f41c91f6fb557056be188e70bf6e 331 Gene3D G3DSA:3.30.470.30 2 136 1.8E-22 T 28-03-2018 SMD44_RS42305 1506f41c91f6fb557056be188e70bf6e 331 SUPERFAMILY SSF56091 5 200 4.32E-30 T 28-03-2018 SMD44_RS42305 1506f41c91f6fb557056be188e70bf6e 331 Gene3D G3DSA:2.40.50.140 204 323 3.8E-8 T 28-03-2018 SMD44_RS42305 1506f41c91f6fb557056be188e70bf6e 331 Gene3D G3DSA:3.30.1490.70 137 202 6.6E-13 T 28-03-2018 SMD44_RS06030 b60db64541845935608886a744a4c32f 385 SUPERFAMILY SSF53067 86 372 2.72E-46 T 28-03-2018 SMD44_RS06030 b60db64541845935608886a744a4c32f 385 Gene3D G3DSA:3.30.420.40 211 381 7.4E-37 T 28-03-2018 SMD44_RS06030 b60db64541845935608886a744a4c32f 385 Pfam PF12802 MarR family 20 70 7.2E-8 T 28-03-2018 SMD44_RS06030 b60db64541845935608886a744a4c32f 385 Pfam PF00480 ROK family 89 367 4.9E-37 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS06030 b60db64541845935608886a744a4c32f 385 Gene3D G3DSA:1.10.10.10 14 75 7.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06030 b60db64541845935608886a744a4c32f 385 Gene3D G3DSA:3.30.420.40 76 210 1.1E-33 T 28-03-2018 SMD44_RS06030 b60db64541845935608886a744a4c32f 385 SUPERFAMILY SSF46785 11 72 1.18E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00105 6b59537bf94e6886286cc96c9d759cb1 175 Gene3D G3DSA:3.40.50.300 43 169 5.5E-8 T 28-03-2018 SMD44_RS00105 6b59537bf94e6886286cc96c9d759cb1 175 Pfam PF13401 AAA domain 70 167 3.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS00105 6b59537bf94e6886286cc96c9d759cb1 175 SUPERFAMILY SSF52540 71 170 3.33E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS24990 0838e27327a31c6d751d43dd15fd9292 418 Pfam PF09588 YqaJ-like viral recombinase domain 92 232 3.7E-21 T 28-03-2018 IPR019080 YqaJ viral recombinase SMD44_RS24990 0838e27327a31c6d751d43dd15fd9292 418 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 87 243 1.7E-25 T 28-03-2018 IPR017482 Putative phage-type endonuclease SMD44_RS24990 0838e27327a31c6d751d43dd15fd9292 418 Gene3D G3DSA:3.90.320.10 88 297 1.1E-34 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMD44_RS24990 0838e27327a31c6d751d43dd15fd9292 418 SUPERFAMILY SSF52980 90 278 1.34E-29 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 Pfam PF01494 FAD binding domain 3 343 2.5E-77 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 SUPERFAMILY SSF54373 175 275 9.02E-39 T 28-03-2018 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 Gene3D G3DSA:3.50.50.60 3 171 4.4E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 SUPERFAMILY SSF51905 1 170 3.2E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 SUPERFAMILY SSF51905 274 377 3.2E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 Gene3D G3DSA:3.30.9.10 172 284 1.2E-51 T 28-03-2018 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 Gene3D G3DSA:3.30.9.10 317 388 2.8E-15 T 28-03-2018 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 6.8E-27 T 28-03-2018 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 6.8E-27 T 28-03-2018 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.8E-27 T 28-03-2018 SMD44_RS16740 61867a75efac872388a501e5b1de9397 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 6.8E-27 T 28-03-2018 SMD44_RS07720 fbe9b21dc0e1008617d27b0e1e1eb3f7 393 SUPERFAMILY SSF51695 60 383 1.1E-77 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS07720 fbe9b21dc0e1008617d27b0e1e1eb3f7 393 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 66 382 3.1E-45 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD44_RS07720 fbe9b21dc0e1008617d27b0e1e1eb3f7 393 Gene3D G3DSA:3.20.20.190 54 391 2.6E-68 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS34005 7689b1d8eb3370c0bba67e6a79014037 338 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 336 1.0E-176 T 28-03-2018 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 SMD44_RS34005 7689b1d8eb3370c0bba67e6a79014037 338 Pfam PF00296 Luciferase-like monooxygenase 10 311 2.1E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS34005 7689b1d8eb3370c0bba67e6a79014037 338 Gene3D G3DSA:3.20.20.30 1 337 3.2E-60 T 28-03-2018 SMD44_RS34005 7689b1d8eb3370c0bba67e6a79014037 338 SUPERFAMILY SSF51679 2 334 3.79E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS14990 fbc958cd23126f67f595879595f199a9 600 Pfam PF04183 IucA / IucC family 152 401 2.2E-75 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMD44_RS14990 fbc958cd23126f67f595879595f199a9 600 Pfam PF06276 Ferric iron reductase FhuF-like transporter 423 579 3.8E-44 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain SMD44_RS14445 2c3bb0498a5f1b984bfba1d1d0989f92 178 SMART SM00507 70 119 1.1E-13 T 28-03-2018 IPR003615 HNH nuclease SMD44_RS14445 2c3bb0498a5f1b984bfba1d1d0989f92 178 Gene3D G3DSA:3.40.1800.10 65 135 4.0E-19 T 28-03-2018 SMD44_RS14445 2c3bb0498a5f1b984bfba1d1d0989f92 178 Pfam PF14279 HNH endonuclease 83 125 5.9E-13 T 28-03-2018 IPR029471 HNH endonuclease 5 SMD44_RS01270 2738ecc36540af6bede5794dde091de9 322 Pfam PF01966 HD domain 51 174 7.1E-11 T 28-03-2018 IPR006674 HD domain SMD44_RS01270 2738ecc36540af6bede5794dde091de9 322 SMART SM00471 47 174 1.4E-5 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS01270 2738ecc36540af6bede5794dde091de9 322 SUPERFAMILY SSF109604 5 265 8.27E-29 T 28-03-2018 SMD44_RS01270 2738ecc36540af6bede5794dde091de9 322 Gene3D G3DSA:1.10.3210.10 4 258 1.3E-20 T 28-03-2018 SMD44_RS24380 6da8201be68e6eb071538da1e8f91c96 211 Pfam PF08281 Sigma-70, region 4 132 182 7.4E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24380 6da8201be68e6eb071538da1e8f91c96 211 Gene3D G3DSA:1.10.10.10 92 189 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24380 6da8201be68e6eb071538da1e8f91c96 211 Pfam PF04542 Sigma-70 region 2 30 98 3.2E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24380 6da8201be68e6eb071538da1e8f91c96 211 SUPERFAMILY SSF88946 15 110 7.32E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24380 6da8201be68e6eb071538da1e8f91c96 211 SUPERFAMILY SSF88659 123 187 4.14E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24380 6da8201be68e6eb071538da1e8f91c96 211 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 186 5.9E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS24380 6da8201be68e6eb071538da1e8f91c96 211 Gene3D G3DSA:1.10.1740.10 11 91 1.1E-21 T 28-03-2018 SMD44_RS34170 babb0e4d10e64309ec95e3b4e72647f7 218 Pfam PF02666 Phosphatidylserine decarboxylase 59 212 4.5E-31 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 SMD44_RS34170 babb0e4d10e64309ec95e3b4e72647f7 218 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 17 218 32.724 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 SMD44_RS34170 babb0e4d10e64309ec95e3b4e72647f7 218 Gene3D G3DSA:2.40.50.100 104 214 7.9E-4 T 28-03-2018 SMD44_RS34170 babb0e4d10e64309ec95e3b4e72647f7 218 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 31 217 4.7E-54 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 SMD44_RS23865 8ae54659f0527068536a756f23e651e2 170 Gene3D G3DSA:3.40.630.30 1 149 8.6E-22 T 28-03-2018 SMD44_RS23865 8ae54659f0527068536a756f23e651e2 170 SUPERFAMILY SSF55729 1 131 6.73E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS23865 8ae54659f0527068536a756f23e651e2 170 Pfam PF13508 Acetyltransferase (GNAT) domain 38 122 6.8E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS03205 3946476321ae0637b9d5436c8c2ce6b3 297 SUPERFAMILY SSF51658 14 272 5.11E-47 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS03205 3946476321ae0637b9d5436c8c2ce6b3 297 Gene3D G3DSA:3.20.20.150 14 293 1.1E-41 T 28-03-2018 SMD44_RS03205 3946476321ae0637b9d5436c8c2ce6b3 297 Pfam PF01261 Xylose isomerase-like TIM barrel 38 227 5.9E-24 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 Gene3D G3DSA:1.10.10.10 16 121 2.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 Pfam PF01022 Bacterial regulatory protein, arsR family 46 93 4.4E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 5.5E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 74 5.5E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 5.5E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 91 106 5.5E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 65 83 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 SMART SM00418 39 120 1.3E-27 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS11685 98db3acd9e82d46efc7fbc46401a8afd 131 SUPERFAMILY SSF46785 25 118 1.41E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 Gene3D G3DSA:3.30.565.10 206 361 3.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 SMART SM00388 140 204 6.8E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 SMART SM00387 246 359 4.5E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 Gene3D G3DSA:1.10.287.130 145 200 5.4E-12 T 28-03-2018 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 SUPERFAMILY SSF55874 207 357 4.19E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 Gene3D G3DSA:3.30.450.20 92 144 4.1E-4 T 28-03-2018 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 357 1.5E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 203 3.2E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 Pfam PF00672 HAMP domain 87 135 1.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 SMART SM00304 86 139 7.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 SUPERFAMILY SSF158472 88 136 5.49E-8 T 28-03-2018 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 356 5.3E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 5.3E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 337 5.3E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS22800 962585a745cf021f6005f66fb26374f3 363 SUPERFAMILY SSF47384 123 203 7.06E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS25250 224a2971c6a3182b04dd3fd0b64bd5a4 461 SUPERFAMILY SSF55874 350 459 4.88E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS25250 224a2971c6a3182b04dd3fd0b64bd5a4 461 Gene3D G3DSA:3.30.565.10 256 460 4.8E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS25250 224a2971c6a3182b04dd3fd0b64bd5a4 461 Pfam PF13796 Putative sensor 57 245 3.6E-48 T 28-03-2018 IPR025828 Putative sensor domain SMD44_RS25250 224a2971c6a3182b04dd3fd0b64bd5a4 461 Pfam PF07730 Histidine kinase 273 338 3.5E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS03455 c6704b6ab215b04e759158db9db1e8c4 514 Gene3D G3DSA:2.30.38.10 331 412 7.8E-28 T 28-03-2018 SMD44_RS03455 c6704b6ab215b04e759158db9db1e8c4 514 Pfam PF00501 AMP-binding enzyme 29 419 1.6E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS03455 c6704b6ab215b04e759158db9db1e8c4 514 Gene3D G3DSA:3.40.50.980 178 330 2.3E-38 T 28-03-2018 SMD44_RS03455 c6704b6ab215b04e759158db9db1e8c4 514 Gene3D G3DSA:3.40.50.980 19 177 1.1E-44 T 28-03-2018 SMD44_RS03455 c6704b6ab215b04e759158db9db1e8c4 514 Gene3D G3DSA:3.30.300.30 414 514 1.4E-26 T 28-03-2018 SMD44_RS03455 c6704b6ab215b04e759158db9db1e8c4 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 501 1.8E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS03455 c6704b6ab215b04e759158db9db1e8c4 514 SUPERFAMILY SSF56801 23 512 1.31E-148 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 275 3.7E-30 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 276 293 3.7E-30 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 242 3.7E-30 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 189 203 3.7E-30 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 301 312 3.7E-30 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 13 139 1.2E-52 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 13 376 8.2E-137 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00097 Anthranilate synthase component II signature 259 270 1.8E-5 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00097 Anthranilate synthase component II signature 350 363 1.8E-5 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00097 Anthranilate synthase component II signature 231 240 1.8E-5 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 Gene3D G3DSA:3.50.30.20 10 153 1.3E-63 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 SMART SM01097 11 141 8.9E-89 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 350 363 8.0E-11 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 240 8.0E-11 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 259 270 8.0E-11 T 28-03-2018 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 11 379 46.136 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 SUPERFAMILY SSF52021 12 147 3.4E-56 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 SUPERFAMILY SSF52317 160 378 5.38E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 Gene3D G3DSA:3.40.50.880 154 380 1.2E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS07260 8b76ad0568005b61aa94cf6b1c639575 380 Pfam PF00117 Glutamine amidotransferase class-I 193 372 6.9E-38 T 28-03-2018 IPR017926 Glutamine amidotransferase SMD44_RS05415 dadbfc20513db84a203610eb4ebc61fc 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 1.8E-5 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMD44_RS05415 dadbfc20513db84a203610eb4ebc61fc 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 1.3E-7 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMD44_RS29255 8d398cf452856e94dbbdbb42339ab33d 454 Gene3D G3DSA:3.40.190.10 21 206 9.4E-34 T 28-03-2018 SMD44_RS29255 8d398cf452856e94dbbdbb42339ab33d 454 Gene3D G3DSA:3.40.190.10 239 406 1.6E-14 T 28-03-2018 SMD44_RS29255 8d398cf452856e94dbbdbb42339ab33d 454 Pfam PF01547 Bacterial extracellular solute-binding protein 54 363 2.6E-33 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS29255 8d398cf452856e94dbbdbb42339ab33d 454 SUPERFAMILY SSF53850 23 452 1.17E-79 T 28-03-2018 SMD44_RS17110 cf54dfbcc6c390e642dff32fdfeae76e 183 SUPERFAMILY SSF55826 34 166 5.89E-35 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS17110 cf54dfbcc6c390e642dff32fdfeae76e 183 Pfam PF04073 Aminoacyl-tRNA editing domain 39 155 5.0E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS17110 cf54dfbcc6c390e642dff32fdfeae76e 183 Gene3D G3DSA:3.90.960.10 11 168 6.2E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD44_RS28840 8cd8c47b0cc324e1688a02f1c2624d4e 215 SUPERFAMILY SSF55821 5 210 7.02E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD44_RS28840 8cd8c47b0cc324e1688a02f1c2624d4e 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 207 2.2E-54 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 SMD44_RS28840 8cd8c47b0cc324e1688a02f1c2624d4e 215 Pfam PF01300 Telomere recombination 23 197 1.2E-45 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 SMD44_RS28840 8cd8c47b0cc324e1688a02f1c2624d4e 215 Gene3D G3DSA:3.90.870.10 1 213 3.8E-66 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD44_RS02990 85130bc359dbcb706e0f2fd26b5efe0d 238 Pfam PF10615 Protein of unknown function (DUF2470) 142 217 5.1E-10 T 28-03-2018 IPR019595 Domain of unknown function DUF2470 SMD44_RS02990 85130bc359dbcb706e0f2fd26b5efe0d 238 SUPERFAMILY SSF50475 46 224 4.32E-12 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS02990 85130bc359dbcb706e0f2fd26b5efe0d 238 Gene3D G3DSA:3.20.180.10 130 223 3.6E-20 T 28-03-2018 IPR019595 Domain of unknown function DUF2470 SMD44_RS08280 92cb09e27f261929b0afca3dd8edb6d5 397 Gene3D G3DSA:1.10.287.100 218 257 8.9E-7 T 28-03-2018 SMD44_RS08280 92cb09e27f261929b0afca3dd8edb6d5 397 Pfam PF09754 PAC2 family 19 236 1.1E-50 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 SMD44_RS08280 92cb09e27f261929b0afca3dd8edb6d5 397 SUPERFAMILY SSF159659 3 260 9.42E-88 T 28-03-2018 SMD44_RS37080 b0058de9cbbfe6a2074edd7ef7212724 481 Gene3D G3DSA:3.40.50.720 42 469 1.8E-49 T 28-03-2018 SMD44_RS37080 b0058de9cbbfe6a2074edd7ef7212724 481 Pfam PF00106 short chain dehydrogenase 137 226 4.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS37080 b0058de9cbbfe6a2074edd7ef7212724 481 SUPERFAMILY SSF51735 322 427 2.31E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS37080 b0058de9cbbfe6a2074edd7ef7212724 481 SUPERFAMILY SSF51735 133 231 2.31E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS06055 cf7b1a42c46fb1dc9ab3c2b22f3a1462 491 Pfam PF00583 Acetyltransferase (GNAT) family 380 452 2.0E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS06055 cf7b1a42c46fb1dc9ab3c2b22f3a1462 491 SUPERFAMILY SSF55021 130 176 8.81E-5 T 28-03-2018 SMD44_RS06055 cf7b1a42c46fb1dc9ab3c2b22f3a1462 491 Gene3D G3DSA:3.40.630.30 320 459 1.6E-20 T 28-03-2018 SMD44_RS06055 cf7b1a42c46fb1dc9ab3c2b22f3a1462 491 Gene3D G3DSA:3.30.70.260 129 201 9.2E-10 T 28-03-2018 SMD44_RS06055 cf7b1a42c46fb1dc9ab3c2b22f3a1462 491 SUPERFAMILY SSF55729 316 455 1.31E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS06850 fea1abf21229308e627c920d106d0a38 472 Gene3D G3DSA:1.25.10.10 12 318 1.7E-6 T 28-03-2018 IPR011989 Armadillo-like helical SMD44_RS06850 fea1abf21229308e627c920d106d0a38 472 SUPERFAMILY SSF48371 234 431 1.44E-5 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS06850 fea1abf21229308e627c920d106d0a38 472 Gene3D G3DSA:1.25.40.70 337 466 0.16 T 28-03-2018 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 Gene3D G3DSA:1.25.40.10 562 591 1.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 Gene3D G3DSA:1.25.40.10 592 684 7.8E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 Gene3D G3DSA:3.30.70.100 535 561 8.2E-10 T 28-03-2018 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 SUPERFAMILY SSF48452 481 687 2.87E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 SUPERFAMILY SSF52540 40 300 1.68E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 SMART SM00028 566 599 4.3 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 SMART SM00028 486 519 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 SMART SM00028 526 559 20.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 SMART SM00028 606 639 3.8 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 Gene3D G3DSA:3.40.50.300 35 200 5.2E-12 T 28-03-2018 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 Pfam PF13424 Tetratricopeptide repeat 569 637 3.3E-10 T 28-03-2018 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 Pfam PF13424 Tetratricopeptide repeat 490 558 6.6E-10 T 28-03-2018 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 Gene3D G3DSA:1.10.150.200 471 534 3.9E-9 T 28-03-2018 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 PRINTS PR00364 Disease resistance protein signature 233 247 3.2E-5 T 28-03-2018 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 PRINTS PR00364 Disease resistance protein signature 149 163 3.2E-5 T 28-03-2018 SMD44_RS04790 58a95378644f4f957086302a4b8dd738 694 PRINTS PR00364 Disease resistance protein signature 71 86 3.2E-5 T 28-03-2018 SMD44_RS02795 21c7842bff289ace415e01557c4f98e7 334 Gene3D G3DSA:3.10.310.10 149 310 2.4E-53 T 28-03-2018 SMD44_RS02795 21c7842bff289ace415e01557c4f98e7 334 Gene3D G3DSA:3.10.310.10 1 148 7.6E-37 T 28-03-2018 SMD44_RS02795 21c7842bff289ace415e01557c4f98e7 334 PIRSF PIRSF029792 1 334 1.3E-125 T 28-03-2018 IPR008794 Proline racemase family SMD44_RS02795 21c7842bff289ace415e01557c4f98e7 334 SUPERFAMILY SSF54506 2 332 4.32E-114 T 28-03-2018 SMD44_RS02795 21c7842bff289ace415e01557c4f98e7 334 Pfam PF05544 Proline racemase 10 332 5.0E-125 T 28-03-2018 IPR008794 Proline racemase family SMD44_RS35325 7850580715b0250472f31cf94b86c1a8 146 Pfam PF04237 YjbR 37 130 1.2E-16 T 28-03-2018 IPR007351 Uncharacterised protein YjbR SMD44_RS35325 7850580715b0250472f31cf94b86c1a8 146 SUPERFAMILY SSF142906 28 143 1.57E-22 T 28-03-2018 SMD44_RS35325 7850580715b0250472f31cf94b86c1a8 146 Gene3D G3DSA:3.30.1460.30 27 132 4.6E-9 T 28-03-2018 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 296 8.1E-91 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 SUPERFAMILY SSF52943 3 296 1.96E-79 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 296 32.909 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 Gene3D G3DSA:1.10.287.80 244 291 7.8E-13 T 28-03-2018 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 Gene3D G3DSA:1.10.287.80 3 42 4.9E-13 T 28-03-2018 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 Pfam PF00231 ATP synthase 4 296 6.0E-86 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 PRINTS PR00126 ATP synthase gamma subunit signature 243 262 2.0E-29 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 PRINTS PR00126 ATP synthase gamma subunit signature 274 295 2.0E-29 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.0E-29 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 2.0E-29 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28890 ab3e6656970637fd6041c10daef45330 305 Gene3D G3DSA:3.40.1380.10 43 243 2.0E-67 T 28-03-2018 SMD44_RS21515 50202e1138ba3127d741285cd9b93f36 391 Gene3D G3DSA:3.40.50.1970 11 188 8.5E-32 T 28-03-2018 SMD44_RS21515 50202e1138ba3127d741285cd9b93f36 391 Gene3D G3DSA:1.20.1090.10 189 391 2.8E-32 T 28-03-2018 SMD44_RS21515 50202e1138ba3127d741285cd9b93f36 391 Pfam PF00465 Iron-containing alcohol dehydrogenase 21 380 4.5E-73 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 SMD44_RS21515 50202e1138ba3127d741285cd9b93f36 391 SUPERFAMILY SSF56796 21 388 8.5E-70 T 28-03-2018 SMD44_RS02720 a2fbbddf02bb0716b92455a908076463 156 Pfam PF01047 MarR family 39 97 2.4E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS02720 a2fbbddf02bb0716b92455a908076463 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 2.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS02720 a2fbbddf02bb0716b92455a908076463 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 2.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS02720 a2fbbddf02bb0716b92455a908076463 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 2.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS02720 a2fbbddf02bb0716b92455a908076463 156 SUPERFAMILY SSF46785 5 144 1.58E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02720 a2fbbddf02bb0716b92455a908076463 156 SMART SM00347 32 130 1.0E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS02720 a2fbbddf02bb0716b92455a908076463 156 Gene3D G3DSA:1.10.10.10 6 144 1.6E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17465 4bde2389b1eba68467bfcb620e1e7fda 482 Pfam PF07063 Domain of unknown function (DUF1338) 24 421 2.3E-99 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 SMD44_RS17465 4bde2389b1eba68467bfcb620e1e7fda 482 SMART SM01150 26 421 3.3E-170 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 SMD44_RS17465 4bde2389b1eba68467bfcb620e1e7fda 482 Gene3D G3DSA:3.10.180.10 80 298 0.002 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS26355 1418974846553d631e006ae75589577b 184 Gene3D G3DSA:1.20.120.450 1 184 2.5E-38 T 28-03-2018 SMD44_RS26355 1418974846553d631e006ae75589577b 184 Pfam PF04978 Protein of unknown function (DUF664) 39 180 1.4E-35 T 28-03-2018 IPR007061 Protein of unknown function DUF664 SMD44_RS26355 1418974846553d631e006ae75589577b 184 SUPERFAMILY SSF109854 12 179 7.94E-35 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS18345 861f8891ef11cedf0a885ab788624fbf 257 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 83 2.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18345 861f8891ef11cedf0a885ab788624fbf 257 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 243 2.7E-29 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS18345 861f8891ef11cedf0a885ab788624fbf 257 SUPERFAMILY SSF46689 27 90 6.48E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS18345 861f8891ef11cedf0a885ab788624fbf 257 SUPERFAMILY SSF48498 101 247 1.07E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS18345 861f8891ef11cedf0a885ab788624fbf 257 Gene3D G3DSA:1.10.357.10 96 256 2.1E-37 T 28-03-2018 SMD44_RS18345 861f8891ef11cedf0a885ab788624fbf 257 Gene3D G3DSA:1.10.10.60 20 89 7.4E-18 T 28-03-2018 SMD44_RS10330 5a0d0f6ad9b8e1497bf0419e346157da 286 SUPERFAMILY SSF47413 14 71 1.89E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS10330 5a0d0f6ad9b8e1497bf0419e346157da 286 SMART SM00530 18 73 8.0E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS10330 5a0d0f6ad9b8e1497bf0419e346157da 286 Gene3D G3DSA:1.10.3100.10 12 160 6.8E-13 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS10330 5a0d0f6ad9b8e1497bf0419e346157da 286 Pfam PF13560 Helix-turn-helix domain 15 75 1.7E-12 T 28-03-2018 SMD44_RS27370 e05714b24c65d471dca1abec9f07537f 340 SUPERFAMILY SSF55729 2 155 2.04E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS27370 e05714b24c65d471dca1abec9f07537f 340 Gene3D G3DSA:3.40.630.30 2 184 7.1E-15 T 28-03-2018 SMD44_RS27370 e05714b24c65d471dca1abec9f07537f 340 Pfam PF13523 Acetyltransferase (GNAT) domain 9 154 3.2E-21 T 28-03-2018 SMD44_RS09740 b0e2a83eb9da3526768f5ce8c9f13787 373 Gene3D G3DSA:3.40.50.720 9 152 1.3E-35 T 28-03-2018 SMD44_RS09740 b0e2a83eb9da3526768f5ce8c9f13787 373 SUPERFAMILY SSF55347 139 310 1.8E-22 T 28-03-2018 SMD44_RS09740 b0e2a83eb9da3526768f5ce8c9f13787 373 Gene3D G3DSA:3.30.360.10 153 373 8.3E-33 T 28-03-2018 SMD44_RS09740 b0e2a83eb9da3526768f5ce8c9f13787 373 SUPERFAMILY SSF51735 9 184 7.03E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09740 b0e2a83eb9da3526768f5ce8c9f13787 373 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 131 5.0E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS00605 919b2a6462a102f5965b0b7009221573 363 Gene3D G3DSA:3.40.50.1820 6 361 1.3E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS00605 919b2a6462a102f5965b0b7009221573 363 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 3 274 1.5E-75 T 28-03-2018 IPR018712 Domain of unknown function DUF2235 SMD44_RS00605 919b2a6462a102f5965b0b7009221573 363 SUPERFAMILY SSF53474 5 158 4.3E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02705 514979d5f8ce8a832aa3b23ebece6bdf 272 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 16 242 6.9E-22 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS02705 514979d5f8ce8a832aa3b23ebece6bdf 272 Gene3D G3DSA:1.20.120.450 1 144 1.8E-16 T 28-03-2018 SMD44_RS02705 514979d5f8ce8a832aa3b23ebece6bdf 272 SUPERFAMILY SSF109854 11 137 1.72E-9 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS02705 514979d5f8ce8a832aa3b23ebece6bdf 272 Pfam PF07398 MDMPI C-terminal domain 150 260 2.5E-10 T 28-03-2018 IPR010872 MDMPI C-terminal SMD44_RS02705 514979d5f8ce8a832aa3b23ebece6bdf 272 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 137 9.9E-23 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS27330 c13a6346bda07696074d359928aafa06 357 ProSitePatterns PS01095 Chitinases family 18 active site. 175 183 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMD44_RS27330 c13a6346bda07696074d359928aafa06 357 Pfam PF00704 Glycosyl hydrolases family 18 69 338 1.7E-30 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMD44_RS27330 c13a6346bda07696074d359928aafa06 357 Gene3D G3DSA:3.20.20.80 61 356 9.7E-49 T 28-03-2018 SMD44_RS27330 c13a6346bda07696074d359928aafa06 357 SMART SM00636 67 338 1.7E-10 T 28-03-2018 IPR011583 Chitinase II GO:0008061 SMD44_RS27330 c13a6346bda07696074d359928aafa06 357 SUPERFAMILY SSF51445 64 345 9.54E-55 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS40565 083efe746a637949510256795eaca6e0 151 Gene3D G3DSA:3.10.180.10 1 149 4.2E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS40565 083efe746a637949510256795eaca6e0 151 SUPERFAMILY SSF54593 2 125 1.97E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS40565 083efe746a637949510256795eaca6e0 151 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 110 2.2E-17 T 28-03-2018 SMD44_RS11235 11742d02306a3e4c98db6aaaa410b5a7 417 Pfam PF07730 Histidine kinase 190 229 4.3E-6 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS11235 11742d02306a3e4c98db6aaaa410b5a7 417 SUPERFAMILY SSF55874 297 407 3.67E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11235 11742d02306a3e4c98db6aaaa410b5a7 417 Gene3D G3DSA:3.30.565.10 247 408 1.9E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11235 11742d02306a3e4c98db6aaaa410b5a7 417 SMART SM00387 309 408 5.0E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11235 11742d02306a3e4c98db6aaaa410b5a7 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 407 1.7E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 PRINTS PR00412 Epoxide hydrolase signature 257 279 2.3E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 PRINTS PR00412 Epoxide hydrolase signature 105 118 2.3E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 PRINTS PR00412 Epoxide hydrolase signature 38 56 2.3E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 7.7E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 226 240 7.7E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 7.7E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 Gene3D G3DSA:3.40.50.1820 11 288 2.3E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 SUPERFAMILY SSF53474 18 281 1.68E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS29745 77a4272b196139328fb503266d2d34de 288 Pfam PF12697 Alpha/beta hydrolase family 34 272 1.8E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS12240 0d335aaaab816bf472cb2e3e073c55da 297 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 247 1.3E-68 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMD44_RS12240 0d335aaaab816bf472cb2e3e073c55da 297 Gene3D G3DSA:3.40.1390.30 112 233 5.2E-37 T 28-03-2018 SMD44_RS12240 0d335aaaab816bf472cb2e3e073c55da 297 Gene3D G3DSA:3.40.1390.30 2 111 1.5E-35 T 28-03-2018 SMD44_RS12240 0d335aaaab816bf472cb2e3e073c55da 297 SUPERFAMILY SSF102705 3 269 5.76E-80 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMD44_RS12240 0d335aaaab816bf472cb2e3e073c55da 297 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 4 265 5.0E-48 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMD44_RS08105 a621e4056a5c2e0fb606bf534bd10be7 339 Gene3D G3DSA:3.40.50.300 80 326 0.0012 T 28-03-2018 SMD44_RS08105 a621e4056a5c2e0fb606bf534bd10be7 339 PIRSF PIRSF016838 2 324 1.8E-82 T 28-03-2018 IPR028349 Protein PafC SMD44_RS08105 a621e4056a5c2e0fb606bf534bd10be7 339 Pfam PF13280 WYL domain 148 315 1.8E-30 T 28-03-2018 IPR026881 WYL domain SMD44_RS08105 a621e4056a5c2e0fb606bf534bd10be7 339 Gene3D G3DSA:1.10.10.10 1 48 0.0056 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33855 6449ad24a9da34e01fc1874dbfa8215b 189 Gene3D G3DSA:2.60.60.30 21 185 1.3E-27 T 28-03-2018 SMD44_RS33855 6449ad24a9da34e01fc1874dbfa8215b 189 Pfam PF02342 TerD domain 1 176 2.4E-25 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS26230 12317286e23be3405c08019a1d1c4dcd 403 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 402 6.1E-140 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain SMD44_RS26230 12317286e23be3405c08019a1d1c4dcd 403 SUPERFAMILY SSF56059 3 169 1.69E-73 T 28-03-2018 SMD44_RS26230 12317286e23be3405c08019a1d1c4dcd 403 SUPERFAMILY SSF56059 279 401 1.69E-73 T 28-03-2018 SMD44_RS26230 12317286e23be3405c08019a1d1c4dcd 403 SUPERFAMILY SSF52440 178 292 3.74E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS03230 8c85e62ccc4eefe16e7506cccd9be12e 407 Pfam PF00480 ROK family 94 389 6.4E-56 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS03230 8c85e62ccc4eefe16e7506cccd9be12e 407 Gene3D G3DSA:3.30.420.40 84 210 1.7E-28 T 28-03-2018 SMD44_RS03230 8c85e62ccc4eefe16e7506cccd9be12e 407 SUPERFAMILY SSF46785 28 83 1.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03230 8c85e62ccc4eefe16e7506cccd9be12e 407 SUPERFAMILY SSF53067 94 392 6.72E-58 T 28-03-2018 SMD44_RS03230 8c85e62ccc4eefe16e7506cccd9be12e 407 Gene3D G3DSA:3.30.420.40 211 396 7.2E-53 T 28-03-2018 SMD44_RS03230 8c85e62ccc4eefe16e7506cccd9be12e 407 Pfam PF12802 MarR family 27 72 7.4E-8 T 28-03-2018 SMD44_RS03230 8c85e62ccc4eefe16e7506cccd9be12e 407 ProSitePatterns PS01125 ROK family signature. 226 253 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS03230 8c85e62ccc4eefe16e7506cccd9be12e 407 Gene3D G3DSA:1.10.10.10 26 83 4.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35635 845727bbbb6a3047d026bd2bf7d0abd6 67 Gene3D G3DSA:1.10.260.40 32 62 1.6E-4 T 28-03-2018 SMD44_RS35635 845727bbbb6a3047d026bd2bf7d0abd6 67 Gene3D G3DSA:1.10.10.60 3 31 3.8E-8 T 28-03-2018 SMD44_RS35635 845727bbbb6a3047d026bd2bf7d0abd6 67 Pfam PF08281 Sigma-70, region 4 4 42 3.3E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS35635 845727bbbb6a3047d026bd2bf7d0abd6 67 SUPERFAMILY SSF88659 7 42 4.8E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21945 85df82664322b145178e33935912dd0c 164 Gene3D G3DSA:3.30.565.10 32 152 3.9E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS21945 85df82664322b145178e33935912dd0c 164 Pfam PF13581 Histidine kinase-like ATPase domain 37 137 2.8E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS21945 85df82664322b145178e33935912dd0c 164 SUPERFAMILY SSF55874 64 133 2.53E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 165 1.7E-58 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 69 4.3E-14 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 12 167 34.548 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 Gene3D G3DSA:3.40.50.620 2 167 6.4E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 21 84 2.0E-4 T 28-03-2018 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 Pfam PF01467 Cytidylyltransferase-like 16 142 8.0E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 12 30 1.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 59 83 1.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 121 143 1.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 30 51 1.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 95 111 1.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMD44_RS30340 dd83bb4c3b2c90326b42d38e28879ca4 169 SUPERFAMILY SSF52374 12 164 5.35E-44 T 28-03-2018 SMD44_RS33975 53c8353e9a03e82b8fffa6b28921c808 188 Gene3D G3DSA:1.20.1250.20 1 187 1.4E-13 T 28-03-2018 SMD44_RS33975 53c8353e9a03e82b8fffa6b28921c808 188 SUPERFAMILY SSF103473 3 177 3.27E-15 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS33975 53c8353e9a03e82b8fffa6b28921c808 188 Pfam PF07690 Major Facilitator Superfamily 7 184 4.4E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS04980 5b58cad1ea1902381f604695f6c04896 322 Gene3D G3DSA:3.40.50.1100 1 117 3.8E-27 T 28-03-2018 SMD44_RS04980 5b58cad1ea1902381f604695f6c04896 322 Gene3D G3DSA:3.40.50.1100 118 322 3.3E-50 T 28-03-2018 SMD44_RS04980 5b58cad1ea1902381f604695f6c04896 322 SUPERFAMILY SSF53686 8 316 5.76E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS04980 5b58cad1ea1902381f604695f6c04896 322 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 47 60 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SMD44_RS04980 5b58cad1ea1902381f604695f6c04896 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 308 1.1E-79 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS11900 ca30c0443a515883c6d2ba3ad683c11e 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 280 1.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS11900 ca30c0443a515883c6d2ba3ad683c11e 287 SUPERFAMILY SSF161098 4 286 4.11E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS11900 ca30c0443a515883c6d2ba3ad683c11e 287 Gene3D G3DSA:1.10.3720.10 60 282 8.6E-36 T 28-03-2018 SMD44_RS24545 0e7872fe1c39b3633723d4f339be0064 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 285 7.9E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS24545 0e7872fe1c39b3633723d4f339be0064 288 Gene3D G3DSA:1.10.3720.10 18 278 1.9E-31 T 28-03-2018 SMD44_RS24545 0e7872fe1c39b3633723d4f339be0064 288 SUPERFAMILY SSF161098 84 273 1.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS36625 077bfc65c328ba6c85d0f6dbdfce9bc0 220 Gene3D G3DSA:3.90.470.20 47 175 5.4E-5 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 Gene3D G3DSA:3.30.70.920 70 159 5.2E-18 T 28-03-2018 SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 Pfam PF01037 Lrp/AsnC ligand binding domain 91 154 1.1E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 SUPERFAMILY SSF46785 17 76 7.12E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 17 64 9.0E-14 T 28-03-2018 SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 Gene3D G3DSA:1.10.10.10 17 68 1.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 SUPERFAMILY SSF54909 80 154 1.33E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 33 2.8E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 44 2.8E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 44 63 2.8E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS21725 799a84921aea8c4101e11df68e465acb 161 SMART SM00344 17 123 4.2E-23 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS19955 70c21ec43e5e53a3a206ea73f5eaec9d 278 SUPERFAMILY SSF109854 11 176 3.3E-17 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS19955 70c21ec43e5e53a3a206ea73f5eaec9d 278 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 249 9.3E-24 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS19955 70c21ec43e5e53a3a206ea73f5eaec9d 278 Pfam PF07398 MDMPI C-terminal domain 187 270 1.1E-7 T 28-03-2018 IPR010872 MDMPI C-terminal SMD44_RS19955 70c21ec43e5e53a3a206ea73f5eaec9d 278 Gene3D G3DSA:1.20.120.450 5 177 9.6E-28 T 28-03-2018 SMD44_RS19955 70c21ec43e5e53a3a206ea73f5eaec9d 278 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 172 1.2E-16 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS30010 6ebf29145be3224b440e3e55e5ba2f82 529 Gene3D G3DSA:2.60.40.380 84 194 3.1E-18 T 28-03-2018 SMD44_RS30010 6ebf29145be3224b440e3e55e5ba2f82 529 Pfam PF00149 Calcineurin-like phosphoesterase 217 406 1.5E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS30010 6ebf29145be3224b440e3e55e5ba2f82 529 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 85 183 3.2E-16 T 28-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 SMD44_RS30010 6ebf29145be3224b440e3e55e5ba2f82 529 Gene3D G3DSA:3.60.21.10 195 529 7.2E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS30010 6ebf29145be3224b440e3e55e5ba2f82 529 SUPERFAMILY SSF49363 80 192 5.75E-16 T 28-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 SMD44_RS30010 6ebf29145be3224b440e3e55e5ba2f82 529 SUPERFAMILY SSF56300 198 525 1.14E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS18675 86c79a7af0001c6959eae18c00b0fe7b 230 Pfam PF03932 CutC family 6 202 6.0E-27 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SMD44_RS18675 86c79a7af0001c6959eae18c00b0fe7b 230 SUPERFAMILY SSF110395 6 228 6.02E-45 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SMD44_RS18675 86c79a7af0001c6959eae18c00b0fe7b 230 Gene3D G3DSA:3.20.20.380 6 230 2.0E-58 T 28-03-2018 SMD44_RS11305 c820b62a82c60e1067fc28123ba21e8a 345 Pfam PF00877 NlpC/P60 family 246 333 2.8E-25 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS11305 c820b62a82c60e1067fc28123ba21e8a 345 Gene3D G3DSA:1.20.120.330 25 213 3.6E-10 T 28-03-2018 SMD44_RS11305 c820b62a82c60e1067fc28123ba21e8a 345 SUPERFAMILY SSF54001 229 335 1.91E-38 T 28-03-2018 SMD44_RS11305 c820b62a82c60e1067fc28123ba21e8a 345 Gene3D G3DSA:3.90.1720.10 223 340 1.1E-38 T 28-03-2018 SMD44_RS23565 807d100f4f8a14d729139d27cb4d10df 762 Gene3D G3DSA:1.25.40.10 51 730 0.0015 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS23565 807d100f4f8a14d729139d27cb4d10df 762 Pfam PF13515 Fusaric acid resistance protein-like 430 551 2.9E-17 T 28-03-2018 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 1 203 8.8E-13 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 326 342 3.6E-8 T 28-03-2018 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 381 3.6E-8 T 28-03-2018 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.6E-8 T 28-03-2018 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 SUPERFAMILY SSF51905 239 406 5.61E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 SUPERFAMILY SSF51905 1 41 5.61E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 SUPERFAMILY SSF51905 81 211 5.61E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 9.6E-12 T 28-03-2018 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 9.6E-12 T 28-03-2018 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 9.6E-12 T 28-03-2018 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 Gene3D G3DSA:3.50.50.60 1 161 8.9E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS21260 4e3f614ab7e703084d1b1f6894b763b0 437 Gene3D G3DSA:3.50.50.60 162 415 9.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS14460 2ad7bdb861763b84c4ffb926d11b81ac 446 SUPERFAMILY SSF53850 40 438 2.17E-63 T 28-03-2018 SMD44_RS14460 2ad7bdb861763b84c4ffb926d11b81ac 446 Gene3D G3DSA:3.40.190.10 229 396 5.0E-11 T 28-03-2018 SMD44_RS14460 2ad7bdb861763b84c4ffb926d11b81ac 446 Gene3D G3DSA:3.40.190.10 33 206 3.5E-39 T 28-03-2018 SMD44_RS14460 2ad7bdb861763b84c4ffb926d11b81ac 446 Pfam PF01547 Bacterial extracellular solute-binding protein 53 354 1.2E-34 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 SMART SM00387 366 470 2.7E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 321 2.5E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 SMART SM00388 255 322 4.3E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 Pfam PF00672 HAMP domain 194 250 2.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 3.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 3.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 3.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 3.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 SUPERFAMILY SSF55874 311 469 2.49E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 Gene3D G3DSA:1.10.287.130 245 318 1.6E-14 T 28-03-2018 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 SMART SM00304 194 254 1.8E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 469 1.0E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 SUPERFAMILY SSF47384 238 322 1.16E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS29170 5f437de231b6d9ef84e53c2ccd0b98c4 470 Gene3D G3DSA:3.30.565.10 326 470 1.1E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 Gene3D G3DSA:3.30.565.10 1 231 3.9E-52 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 Pfam PF00183 Hsp90 protein 229 638 1.8E-125 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 SMART SM00387 28 186 1.8E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 636 29.393 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 PIRSF PIRSF002583 1 639 5.3E-215 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 SUPERFAMILY SSF110942 520 636 6.41E-30 T 28-03-2018 SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 PRINTS PR00775 90kDa heat shock protein signature 77 94 1.6E-58 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 PRINTS PR00775 90kDa heat shock protein signature 124 146 1.6E-58 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 PRINTS PR00775 90kDa heat shock protein signature 6 26 1.6E-58 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 PRINTS PR00775 90kDa heat shock protein signature 27 49 1.6E-58 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 PRINTS PR00775 90kDa heat shock protein signature 174 191 1.6E-58 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 PRINTS PR00775 90kDa heat shock protein signature 197 215 1.6E-58 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 PRINTS PR00775 90kDa heat shock protein signature 95 112 1.6E-58 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 26 35 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 159 7.5E-12 T 28-03-2018 SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 SUPERFAMILY SSF55874 5 222 1.13E-60 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS42125 5c1187eacaee7f745134ebf430f9dcd1 639 SUPERFAMILY SSF54211 238 491 1.14E-90 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS00915 754271cd9d3c63e81e641000ce51ad7d 267 SUPERFAMILY SSF53474 18 262 3.21E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS00915 754271cd9d3c63e81e641000ce51ad7d 267 Pfam PF12697 Alpha/beta hydrolase family 35 259 3.7E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS00915 754271cd9d3c63e81e641000ce51ad7d 267 Gene3D G3DSA:3.40.50.1820 16 264 5.2E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS29500 1b3a1d7d8674e233f265dd547fe5434a 317 Pfam PF00753 Metallo-beta-lactamase superfamily 53 246 5.7E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS29500 1b3a1d7d8674e233f265dd547fe5434a 317 SUPERFAMILY SSF56281 19 302 9.24E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS29500 1b3a1d7d8674e233f265dd547fe5434a 317 SMART SM00849 54 246 5.1E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS29500 1b3a1d7d8674e233f265dd547fe5434a 317 Gene3D G3DSA:3.60.15.10 33 272 1.4E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS12040 f56dea10ab627961d776200ca4c4f32b 519 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 476 511 0.0033 T 28-03-2018 SMD44_RS12040 f56dea10ab627961d776200ca4c4f32b 519 Pfam PF04213 Htaa 263 418 1.1E-35 T 28-03-2018 IPR007331 Htaa SMD44_RS12040 f56dea10ab627961d776200ca4c4f32b 519 Pfam PF04213 Htaa 59 215 6.0E-43 T 28-03-2018 IPR007331 Htaa SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 Pfam PF01494 FAD binding domain 20 370 2.1E-81 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 Gene3D G3DSA:3.50.50.60 14 182 7.2E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 SUPERFAMILY SSF51905 20 190 4.92E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 SUPERFAMILY SSF51905 292 382 4.92E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 Gene3D G3DSA:3.40.30.20 428 498 0.0081 T 28-03-2018 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 1.8E-44 T 28-03-2018 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 21 43 1.8E-44 T 28-03-2018 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 356 372 1.8E-44 T 28-03-2018 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 356 1.8E-44 T 28-03-2018 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 320 1.8E-44 T 28-03-2018 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 1.8E-44 T 28-03-2018 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 Gene3D G3DSA:3.30.9.10 183 314 2.2E-17 T 28-03-2018 SMD44_RS26650 2ce8bbdce1c573a25ecdc2ccefda53eb 507 Gene3D G3DSA:3.30.9.10 315 411 6.8E-20 T 28-03-2018 SMD44_RS20275 12e2a2f8d37de5346627cae0f7e541b2 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 7.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20275 12e2a2f8d37de5346627cae0f7e541b2 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 7.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20275 12e2a2f8d37de5346627cae0f7e541b2 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 7.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20275 12e2a2f8d37de5346627cae0f7e541b2 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 7.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20275 12e2a2f8d37de5346627cae0f7e541b2 167 Gene3D G3DSA:1.10.10.10 1 163 2.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20275 12e2a2f8d37de5346627cae0f7e541b2 167 Pfam PF01047 MarR family 38 89 2.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20275 12e2a2f8d37de5346627cae0f7e541b2 167 SMART SM00347 25 125 1.9E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20275 12e2a2f8d37de5346627cae0f7e541b2 167 SUPERFAMILY SSF46785 36 139 2.42E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01955 5fa59e053be55a2295089fb70e04fc5b 570 Gene3D G3DSA:1.20.1250.20 39 233 5.2E-33 T 28-03-2018 SMD44_RS01955 5fa59e053be55a2295089fb70e04fc5b 570 Gene3D G3DSA:1.20.1250.20 291 543 2.6E-25 T 28-03-2018 SMD44_RS01955 5fa59e053be55a2295089fb70e04fc5b 570 Pfam PF07690 Major Facilitator Superfamily 50 439 1.9E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS01955 5fa59e053be55a2295089fb70e04fc5b 570 SUPERFAMILY SSF103473 502 533 6.02E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS01955 5fa59e053be55a2295089fb70e04fc5b 570 SUPERFAMILY SSF103473 279 450 6.02E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS01955 5fa59e053be55a2295089fb70e04fc5b 570 SUPERFAMILY SSF103473 37 229 6.02E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 SUPERFAMILY SSF53383 32 437 9.08E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 PIRSF PIRSF000521 182 439 5.6E-28 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 PIRSF PIRSF000521 18 142 8.6E-10 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 PIRSF PIRSF000521 137 168 31.0 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 271 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 Gene3D G3DSA:3.90.1150.10 13 184 1.4E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 Gene3D G3DSA:3.40.640.10 185 309 9.3E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 Gene3D G3DSA:3.90.1150.10 310 443 5.1E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS35550 673f82976dbd802c307d75df7bd8f4e9 461 Pfam PF00202 Aminotransferase class-III 42 435 8.0E-89 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS27190 047068d1edb7b02ac0f72adbcc05ba1d 254 Pfam PF01927 Mut7-C RNAse domain 96 237 2.7E-41 T 28-03-2018 IPR002782 Mut7-C RNAse domain SMD44_RS27190 047068d1edb7b02ac0f72adbcc05ba1d 254 Pfam PF14451 Mut7-C ubiquitin 4 82 2.0E-24 T 28-03-2018 IPR027798 Ubiquitin Mut7-C domain SMD44_RS05835 a52bc99d868e324f4748448d0a08854d 275 Gene3D G3DSA:3.40.50.300 1 208 1.3E-48 T 28-03-2018 SMD44_RS05835 a52bc99d868e324f4748448d0a08854d 275 Pfam PF13500 AAA domain 4 202 2.3E-32 T 28-03-2018 SMD44_RS05835 a52bc99d868e324f4748448d0a08854d 275 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 207 25.156 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMD44_RS05835 a52bc99d868e324f4748448d0a08854d 275 SUPERFAMILY SSF52540 1 202 4.91E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS05835 a52bc99d868e324f4748448d0a08854d 275 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 170 5.1E-31 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMD44_RS30070 6dc1c67cc61ca766b5548cdb9f563c10 345 SUPERFAMILY SSF82171 47 326 1.51E-18 T 28-03-2018 SMD44_RS30070 6dc1c67cc61ca766b5548cdb9f563c10 345 Gene3D G3DSA:2.130.10.150 43 196 6.6E-12 T 28-03-2018 SMD44_RS30070 6dc1c67cc61ca766b5548cdb9f563c10 345 Gene3D G3DSA:2.130.10.150 197 344 4.0E-12 T 28-03-2018 SMD44_RS10185 042ccaea6693be5f1bd2c95727ea8ed9 189 SUPERFAMILY SSF101874 20 182 6.28E-42 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS10185 042ccaea6693be5f1bd2c95727ea8ed9 189 SMART SM00867 22 182 1.4E-51 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS10185 042ccaea6693be5f1bd2c95727ea8ed9 189 Gene3D G3DSA:2.40.128.110 18 184 6.7E-47 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS10185 042ccaea6693be5f1bd2c95727ea8ed9 189 Pfam PF04264 YceI-like domain 23 181 1.5E-40 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS07190 971f2d28d25b60843f18e48aefe6c239 158 SUPERFAMILY SSF46785 30 148 5.13E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07190 971f2d28d25b60843f18e48aefe6c239 158 Gene3D G3DSA:1.10.10.10 12 155 2.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15630 923db34a99b6bf90da01d7ea9931067a 437 Pfam PF02378 Phosphotransferase system, EIIC 26 355 1.2E-64 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMD44_RS16265 c5ef6115e76f34031509834baa252764 193 Gene3D G3DSA:3.40.630.30 1 179 4.4E-36 T 28-03-2018 SMD44_RS16265 c5ef6115e76f34031509834baa252764 193 Pfam PF13302 Acetyltransferase (GNAT) domain 10 149 1.6E-30 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS16265 c5ef6115e76f34031509834baa252764 193 SUPERFAMILY SSF55729 1 173 2.3E-44 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 Pfam PF00072 Response regulator receiver domain 5 118 6.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 Gene3D G3DSA:3.40.50.2300 2 129 5.7E-35 T 28-03-2018 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 SUPERFAMILY SSF46894 144 214 3.4E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 SMART SM00421 153 210 4.5E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 4.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 SUPERFAMILY SSF52172 3 131 4.55E-30 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 Gene3D G3DSA:1.10.10.10 130 217 6.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00625 f60a169e99848ec28b41cd514e891467 220 SMART SM00448 3 118 1.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS28005 4912d9fc87985b939017a12d84725ecc 334 SUPERFAMILY SSF161098 110 315 1.26E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS28005 4912d9fc87985b939017a12d84725ecc 334 Gene3D G3DSA:1.10.3720.10 6 321 4.8E-37 T 28-03-2018 SMD44_RS28005 4912d9fc87985b939017a12d84725ecc 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 331 1.1E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13915 ba18c02ad2e535a1597be6d63962f061 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 139 7.6E-8 T 28-03-2018 SMD44_RS13915 ba18c02ad2e535a1597be6d63962f061 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 85 105 7.6E-8 T 28-03-2018 SMD44_RS13915 ba18c02ad2e535a1597be6d63962f061 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 388 407 7.6E-8 T 28-03-2018 SMD44_RS13915 ba18c02ad2e535a1597be6d63962f061 448 Gene3D G3DSA:1.20.1250.20 241 448 1.9E-10 T 28-03-2018 SMD44_RS13915 ba18c02ad2e535a1597be6d63962f061 448 Gene3D G3DSA:1.20.1250.20 1 182 3.3E-26 T 28-03-2018 SMD44_RS13915 ba18c02ad2e535a1597be6d63962f061 448 Pfam PF07690 Major Facilitator Superfamily 2 397 1.3E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS13915 ba18c02ad2e535a1597be6d63962f061 448 SUPERFAMILY SSF103473 236 447 4.88E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS13915 ba18c02ad2e535a1597be6d63962f061 448 SUPERFAMILY SSF103473 2 182 4.88E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17520 34710fdd08c7e729ffd45134b99f0eaa 142 SUPERFAMILY SSF103481 30 129 1.11E-17 T 28-03-2018 SMD44_RS17520 34710fdd08c7e729ffd45134b99f0eaa 142 Pfam PF00893 Small Multidrug Resistance protein 26 117 8.3E-19 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMD44_RS33240 7e5f8489375fad98c97b927bce2209b9 279 Gene3D G3DSA:3.60.15.10 74 269 6.1E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS33240 7e5f8489375fad98c97b927bce2209b9 279 SUPERFAMILY SSF56281 67 251 1.54E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS33240 7e5f8489375fad98c97b927bce2209b9 279 SMART SM00849 83 249 2.2E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 Gene3D G3DSA:3.30.565.10 447 584 6.7E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 SUPERFAMILY SSF55781 34 216 2.55E-37 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 SMART SM00387 479 584 2.7E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 SUPERFAMILY SSF55874 470 581 2.44E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 Pfam PF13185 GAF domain 51 190 4.4E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 Pfam PF13185 GAF domain 220 357 1.6E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 Pfam PF07730 Histidine kinase 374 436 1.4E-10 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 SMART SM00065 220 366 0.0051 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 SMART SM00065 52 199 7.8E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 Gene3D G3DSA:3.30.450.40 3 198 6.2E-35 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 SUPERFAMILY SSF55781 203 383 1.49E-20 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS22880 7de7e19ec5b23b0fa6cd4853dabad390 588 Gene3D G3DSA:3.30.450.40 199 369 2.4E-25 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS34625 ead472f9d0ac6de2dd221b721c48bb10 650 Gene3D G3DSA:2.60.120.200 418 635 1.8E-35 T 28-03-2018 SMD44_RS34625 ead472f9d0ac6de2dd221b721c48bb10 650 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 460 620 3.5E-22 T 28-03-2018 SMD44_RS34625 ead472f9d0ac6de2dd221b721c48bb10 650 SUPERFAMILY SSF50939 62 420 3.36E-86 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD44_RS34625 ead472f9d0ac6de2dd221b721c48bb10 650 SMART SM00282 479 613 2.8E-9 T 28-03-2018 IPR001791 Laminin G domain SMD44_RS34625 ead472f9d0ac6de2dd221b721c48bb10 650 SMART SM00560 479 618 1.6E-27 T 28-03-2018 IPR006558 LamG-like jellyroll fold SMD44_RS34625 ead472f9d0ac6de2dd221b721c48bb10 650 SUPERFAMILY SSF49899 426 623 8.39E-34 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS34625 ead472f9d0ac6de2dd221b721c48bb10 650 Gene3D G3DSA:2.120.10.10 54 417 1.2E-78 T 28-03-2018 SMD44_RS34625 ead472f9d0ac6de2dd221b721c48bb10 650 Pfam PF13088 BNR repeat-like domain 88 393 1.3E-30 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD44_RS20685 af7f9c7acfc0c0b0bd9f391bbab20a95 304 SMART SM00530 47 118 6.0E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS20685 af7f9c7acfc0c0b0bd9f391bbab20a95 304 Gene3D G3DSA:1.10.260.40 30 120 9.3E-12 T 28-03-2018 SMD44_RS20685 af7f9c7acfc0c0b0bd9f391bbab20a95 304 Pfam PF13560 Helix-turn-helix domain 44 117 1.4E-12 T 28-03-2018 SMD44_RS20685 af7f9c7acfc0c0b0bd9f391bbab20a95 304 SUPERFAMILY SSF47413 68 114 4.44E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS01550 fbad7bca9441595241d47434fe088446 292 SUPERFAMILY SSF46785 5 106 2.52E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01550 fbad7bca9441595241d47434fe088446 292 Pfam PF00578 AhpC/TSA family 177 263 1.5E-9 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD44_RS01550 fbad7bca9441595241d47434fe088446 292 Pfam PF01638 HxlR-like helix-turn-helix 18 103 1.2E-21 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS01550 fbad7bca9441595241d47434fe088446 292 Gene3D G3DSA:3.40.30.10 110 283 7.0E-16 T 28-03-2018 SMD44_RS01550 fbad7bca9441595241d47434fe088446 292 Gene3D G3DSA:1.10.10.10 1 103 3.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01550 fbad7bca9441595241d47434fe088446 292 SUPERFAMILY SSF52833 177 282 3.81E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS31880 b70a4b2b844ff8e06039a35cbfff1294 287 Pfam PF03301 Tryptophan 2,3-dioxygenase 22 162 8.6E-25 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMD44_RS31880 b70a4b2b844ff8e06039a35cbfff1294 287 Pfam PF03301 Tryptophan 2,3-dioxygenase 175 242 2.9E-10 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMD44_RS31880 b70a4b2b844ff8e06039a35cbfff1294 287 SUPERFAMILY SSF140959 27 255 3.14E-40 T 28-03-2018 SMD44_RS14720 238305615560d0373113983d1e9e77cf 267 Pfam PF04962 KduI/IolB family 4 263 8.4E-88 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 SMD44_RS14720 238305615560d0373113983d1e9e77cf 267 Gene3D G3DSA:2.60.120.10 15 118 9.1E-39 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS14720 238305615560d0373113983d1e9e77cf 267 PIRSF PIRSF036628 1 266 1.9E-99 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 SMD44_RS14720 238305615560d0373113983d1e9e77cf 267 SUPERFAMILY SSF51182 13 248 2.4E-58 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS14720 238305615560d0373113983d1e9e77cf 267 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 17 263 3.9E-83 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 SMD44_RS14720 238305615560d0373113983d1e9e77cf 267 Gene3D G3DSA:2.60.120.10 119 264 6.6E-62 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 255 3.0E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 Gene3D G3DSA:1.10.540.10 1 159 6.6E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 Gene3D G3DSA:1.20.140.10 267 430 2.5E-35 T 28-03-2018 SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 SUPERFAMILY SSF47203 269 423 2.28E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 SUPERFAMILY SSF56645 99 280 3.78E-58 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 SUPERFAMILY SSF56645 2 67 3.78E-58 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 Gene3D G3DSA:2.40.110.10 160 266 1.2E-30 T 28-03-2018 SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 157 1.0E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS18070 84044c91fe7d2892141eaea876bd5173 435 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 269 421 7.6E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 Gene3D G3DSA:1.10.10.10 1 83 1.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 Gene3D G3DSA:3.40.190.10 180 292 3.8E-21 T 28-03-2018 SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 SUPERFAMILY SSF53850 87 286 3.94E-41 T 28-03-2018 SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 SUPERFAMILY SSF46785 1 83 1.15E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 Pfam PF03466 LysR substrate binding domain 88 286 8.3E-44 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 Gene3D G3DSA:3.40.190.10 87 179 6.0E-29 T 28-03-2018 SMD44_RS02445 98a036b6b7f68fac8622f8fed4007050 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.9E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS41275 e953b08c67c667514c21105f7317cc94 171 Gene3D G3DSA:2.90.10.10 70 141 6.2E-15 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS41275 e953b08c67c667514c21105f7317cc94 171 Gene3D G3DSA:2.90.10.10 142 171 0.0012 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS41275 e953b08c67c667514c21105f7317cc94 171 Pfam PF01453 D-mannose binding lectin 72 141 4.5E-17 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS41275 e953b08c67c667514c21105f7317cc94 171 SUPERFAMILY SSF51110 59 169 4.0E-27 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS41275 e953b08c67c667514c21105f7317cc94 171 SMART SM00108 64 171 4.0E-19 T 28-03-2018 IPR001480 Bulb-type lectin domain SMD44_RS37220 0b73a5dda82fb8682b300f28aae7d29c 480 Pfam PF06762 Lipase maturation factor 121 268 1.5E-56 T 28-03-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 SMD44_RS37220 0b73a5dda82fb8682b300f28aae7d29c 480 Pfam PF06762 Lipase maturation factor 294 471 4.2E-61 T 28-03-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 SMD44_RS32295 d92d1387e28d3ded0541dd10d6f5b9c5 349 SUPERFAMILY SSF53822 23 320 3.03E-61 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS32295 d92d1387e28d3ded0541dd10d6f5b9c5 349 Gene3D G3DSA:3.40.50.2300 20 141 6.1E-17 T 28-03-2018 SMD44_RS32295 d92d1387e28d3ded0541dd10d6f5b9c5 349 Gene3D G3DSA:3.40.50.2300 142 297 2.9E-28 T 28-03-2018 SMD44_RS32295 d92d1387e28d3ded0541dd10d6f5b9c5 349 Pfam PF13407 Periplasmic binding protein domain 31 285 1.5E-57 T 28-03-2018 IPR025997 Periplasmic binding protein SMD44_RS34525 7f4093e1348a48c095bf2d61c6667f9a 307 Gene3D G3DSA:3.40.50.150 4 232 5.4E-25 T 28-03-2018 SMD44_RS34525 7f4093e1348a48c095bf2d61c6667f9a 307 SUPERFAMILY SSF53335 58 231 6.81E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS34525 7f4093e1348a48c095bf2d61c6667f9a 307 Pfam PF13649 Methyltransferase domain 64 160 1.4E-9 T 28-03-2018 SMD44_RS33460 0c82d767a8a3205aa54cd2f1667f8917 161 SUPERFAMILY SSF54637 24 153 1.71E-33 T 28-03-2018 IPR029069 HotDog domain SMD44_RS33460 0c82d767a8a3205aa54cd2f1667f8917 161 Pfam PF13279 Thioesterase-like superfamily 35 140 2.8E-17 T 28-03-2018 SMD44_RS33460 0c82d767a8a3205aa54cd2f1667f8917 161 Gene3D G3DSA:3.10.129.10 19 155 7.0E-27 T 28-03-2018 SMD44_RS12050 72649ed15d5c4601acf7b11c922ee029 341 Gene3D G3DSA:3.40.50.1980 80 184 9.7E-24 T 28-03-2018 SMD44_RS12050 72649ed15d5c4601acf7b11c922ee029 341 SUPERFAMILY SSF53807 62 338 1.84E-44 T 28-03-2018 SMD44_RS12050 72649ed15d5c4601acf7b11c922ee029 341 Pfam PF01497 Periplasmic binding protein 83 313 1.9E-32 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS12050 72649ed15d5c4601acf7b11c922ee029 341 Gene3D G3DSA:3.40.50.1980 185 341 5.9E-31 T 28-03-2018 SMD44_RS10015 b43b5e4bbbb499f4e5575742217a42fe 474 SUPERFAMILY SSF101960 41 471 2.22E-140 T 28-03-2018 SMD44_RS10015 b43b5e4bbbb499f4e5575742217a42fe 474 Pfam PF01458 Uncharacterized protein family (UPF0051) 220 445 1.2E-74 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SMD44_RS10015 b43b5e4bbbb499f4e5575742217a42fe 474 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 18 465 3.7E-220 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 SMD44_RS40715 6f382922a1360707a4da3cdf3ca27612 187 Gene3D G3DSA:3.40.630.30 2 183 1.3E-22 T 28-03-2018 SMD44_RS40715 6f382922a1360707a4da3cdf3ca27612 187 Pfam PF00583 Acetyltransferase (GNAT) family 44 146 1.2E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS40715 6f382922a1360707a4da3cdf3ca27612 187 SUPERFAMILY SSF55729 9 178 1.36E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS35385 53c7dd7e7553812b44ec5360437113bc 427 SMART SM00631 46 264 1.3E-4 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS35385 53c7dd7e7553812b44ec5360437113bc 427 Gene3D G3DSA:3.40.630.10 33 319 1.8E-35 T 28-03-2018 SMD44_RS35385 53c7dd7e7553812b44ec5360437113bc 427 SUPERFAMILY SSF53187 43 227 5.29E-38 T 28-03-2018 SMD44_RS35385 53c7dd7e7553812b44ec5360437113bc 427 Pfam PF00246 Zinc carboxypeptidase 56 166 2.9E-20 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS04950 a934700235690e3e25849dd38d4b60fa 310 Gene3D G3DSA:3.30.2010.10 104 199 5.4E-13 T 28-03-2018 SMD44_RS04950 a934700235690e3e25849dd38d4b60fa 310 Pfam PF01435 Peptidase family M48 136 214 6.2E-9 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD44_RS41495 2f2c2efcaf6102da54e57ec22ebee4c0 146 SUPERFAMILY SSF55620 12 132 3.39E-20 T 28-03-2018 SMD44_RS41495 2f2c2efcaf6102da54e57ec22ebee4c0 146 Gene3D G3DSA:3.30.479.10 3 135 1.0E-20 T 28-03-2018 SMD44_RS41495 2f2c2efcaf6102da54e57ec22ebee4c0 146 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 14 132 2.6E-17 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 SMD44_RS00020 65632524a4520c977f6e1714ac87ee61 322 Gene3D G3DSA:3.40.50.300 45 207 5.8E-7 T 28-03-2018 SMD44_RS00020 65632524a4520c977f6e1714ac87ee61 322 SUPERFAMILY SSF52540 34 301 2.01E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00020 65632524a4520c977f6e1714ac87ee61 322 Pfam PF05621 Bacterial TniB protein 38 299 1.7E-29 T 28-03-2018 IPR008868 Bacterial TniB SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 SUPERFAMILY SSF52540 1 217 7.5E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 Pfam PF00005 ABC transporter 282 442 4.2E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 Pfam PF00005 ABC transporter 14 166 3.8E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 SMART SM00382 23 214 3.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 SMART SM00382 290 498 1.4E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 Gene3D G3DSA:3.40.50.300 261 506 2.0E-33 T 28-03-2018 SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 Gene3D G3DSA:3.40.50.300 1 233 6.5E-52 T 28-03-2018 SMD44_RS40405 cadeb7c0d7a9fe94179b46e53bb94128 515 SUPERFAMILY SSF52540 256 500 2.15E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07630 428cec05ade4b2bce1f6608c1ef904a5 314 Pfam PF01636 Phosphotransferase enzyme family 44 247 2.4E-12 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS07630 428cec05ade4b2bce1f6608c1ef904a5 314 SUPERFAMILY SSF56112 45 247 9.91E-21 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS07630 428cec05ade4b2bce1f6608c1ef904a5 314 Gene3D G3DSA:3.90.1200.10 96 263 1.6E-19 T 28-03-2018 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 2.9E-68 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 Gene3D G3DSA:2.40.50.140 1 123 7.8E-65 T 28-03-2018 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.4E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.4E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.4E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.4E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.4E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.4E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.977 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 SUPERFAMILY SSF50249 2 123 6.77E-53 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 PIRSF PIRSF002133 1 123 9.3E-55 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25475 a0e41c2799cf2c613b8f5763b914b45c 123 Pfam PF00164 Ribosomal protein S12/S23 12 123 7.8E-44 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS10665 4053313b744f526ae3c92f5ab76aa7d8 309 Pfam PF13350 Tyrosine phosphatase family 50 308 3.4E-61 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type SMD44_RS10665 4053313b744f526ae3c92f5ab76aa7d8 309 SUPERFAMILY SSF52799 50 307 5.16E-45 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMD44_RS10665 4053313b744f526ae3c92f5ab76aa7d8 309 Gene3D G3DSA:3.90.190.10 64 253 1.0E-16 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 Pfam PF07739 TipAS antibiotic-recognition domain 132 247 9.5E-36 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 SMART SM00422 3 72 6.2E-31 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 SUPERFAMILY SSF89082 160 246 9.68E-25 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 Pfam PF13411 MerR HTH family regulatory protein 3 70 3.6E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 Gene3D G3DSA:1.10.490.50 162 251 1.8E-24 T 28-03-2018 SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 Gene3D G3DSA:1.10.1660.10 1 161 3.7E-36 T 28-03-2018 SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 SUPERFAMILY SSF46955 3 103 8.79E-30 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS23660 71c3d8346842503274e4c6b0a292c796 256 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS33895 5b97b468b40030b6f7ad81b26659c212 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 258 3.5E-81 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SMD44_RS33895 5b97b468b40030b6f7ad81b26659c212 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 4.5E-20 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS33895 5b97b468b40030b6f7ad81b26659c212 259 SUPERFAMILY SSF56219 1 259 7.2E-68 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS33895 5b97b468b40030b6f7ad81b26659c212 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 6.8E-60 T 28-03-2018 SMD44_RS33895 5b97b468b40030b6f7ad81b26659c212 259 Gene3D G3DSA:3.60.10.10 1 259 9.8E-43 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS21525 3db8d0f4cdbf2f1cf52c05eec73a56dc 438 SUPERFAMILY SSF56059 83 336 1.1E-38 T 28-03-2018 SMD44_RS21525 3db8d0f4cdbf2f1cf52c05eec73a56dc 438 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 3.5E-26 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD44_RS21525 3db8d0f4cdbf2f1cf52c05eec73a56dc 438 SUPERFAMILY SSF52440 2 111 5.76E-26 T 28-03-2018 IPR016185 Pre-ATP-grasp domain SMD44_RS21525 3db8d0f4cdbf2f1cf52c05eec73a56dc 438 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 331 6.8E-26 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD44_RS21525 3db8d0f4cdbf2f1cf52c05eec73a56dc 438 Gene3D G3DSA:3.30.470.20 212 437 3.2E-32 T 28-03-2018 SMD44_RS21525 3db8d0f4cdbf2f1cf52c05eec73a56dc 438 Gene3D G3DSA:3.30.1490.20 119 208 5.6E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS21525 3db8d0f4cdbf2f1cf52c05eec73a56dc 438 Gene3D G3DSA:3.40.50.20 1 118 3.8E-32 T 28-03-2018 SMD44_RS19705 0e2415a6c75b8f8ea142b7301a2a0101 371 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 25 354 4.1E-132 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 SMD44_RS19705 0e2415a6c75b8f8ea142b7301a2a0101 371 Pfam PF01758 Sodium Bile acid symporter family 70 267 1.7E-61 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SMD44_RS19705 0e2415a6c75b8f8ea142b7301a2a0101 371 PIRSF PIRSF005508 11 370 5.8E-139 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 SMD44_RS33085 983054a553304342f14255e135ef5574 150 Pfam PF04965 Gene 25-like lysozyme 26 115 1.9E-21 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD SMD44_RS33085 983054a553304342f14255e135ef5574 150 SUPERFAMILY SSF160719 22 128 1.57E-31 T 28-03-2018 SMD44_RS33085 983054a553304342f14255e135ef5574 150 Gene3D G3DSA:3.10.450.40 1 130 6.9E-41 T 28-03-2018 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 Pfam PF13180 PDZ domain 273 356 8.6E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 Gene3D G3DSA:2.30.42.10 269 358 1.5E-16 T 28-03-2018 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 Gene3D G3DSA:2.40.10.10 155 267 2.5E-31 T 28-03-2018 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 SMART SM00228 241 347 9.0E-4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 SUPERFAMILY SSF50156 241 349 2.89E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 Pfam PF13365 Trypsin-like peptidase domain 81 225 5.6E-30 T 28-03-2018 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 SUPERFAMILY SSF50494 58 265 4.18E-51 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 PRINTS PR00834 HtrA/DegQ protease family signature 90 102 1.1E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 PRINTS PR00834 HtrA/DegQ protease family signature 196 213 1.1E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 PRINTS PR00834 HtrA/DegQ protease family signature 112 132 1.1E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 PRINTS PR00834 HtrA/DegQ protease family signature 154 178 1.1E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 1.1E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 PRINTS PR00834 HtrA/DegQ protease family signature 305 317 1.1E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD44_RS11475 afd511a86e2b1fc41ef1a4d551ff1a05 359 Gene3D G3DSA:2.40.10.10 55 154 1.3E-24 T 28-03-2018 SMD44_RS18850 75ec2de2bc3b88e89c92ab74445fa91a 348 Gene3D G3DSA:2.60.120.260 207 348 6.3E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS18850 75ec2de2bc3b88e89c92ab74445fa91a 348 SUPERFAMILY SSF49785 226 341 2.38E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 409 53.706 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 3 409 3.7E-205 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 39 334 2.1E-79 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 Gene3D G3DSA:1.20.120.640 327 409 3.5E-14 T 28-03-2018 SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 SUPERFAMILY SSF52374 33 334 6.7E-65 T 28-03-2018 SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 Gene3D G3DSA:3.40.50.620 1 326 1.6E-64 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 2.9E-18 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 2.9E-18 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 210 228 2.9E-18 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD44_RS08295 5f0b7a7580023b227b26acda3bbe39da 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 241 262 2.9E-18 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD44_RS21410 f191607d0488bd9d84b12b4008c9a68c 85 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 85 22.42 T 28-03-2018 IPR009619 Cell division protein CrgA SMD44_RS21410 f191607d0488bd9d84b12b4008c9a68c 85 Pfam PF06781 Cell division protein CrgA 2 85 5.4E-29 T 28-03-2018 IPR009619 Cell division protein CrgA SMD44_RS25275 ea5afe51b24d7a8da44ce49072e21f4a 322 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 321 22.308 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25275 ea5afe51b24d7a8da44ce49072e21f4a 322 Pfam PF00146 NADH dehydrogenase 11 314 1.2E-100 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS10950 aee6eb006aaa1ba7172bba00bea3bd45 528 Pfam PF00999 Sodium/hydrogen exchanger family 9 406 7.5E-55 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD44_RS10950 aee6eb006aaa1ba7172bba00bea3bd45 528 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 9 525 4.6E-98 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 SMD44_RS30965 c6be6df1d9259914a66ed5a456bbef0c 598 Gene3D G3DSA:3.40.50.1820 341 590 2.4E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS30965 c6be6df1d9259914a66ed5a456bbef0c 598 SUPERFAMILY SSF53474 396 504 1.82E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS30965 c6be6df1d9259914a66ed5a456bbef0c 598 Gene3D G3DSA:1.10.287.1060 15 111 1.7E-4 T 28-03-2018 SMD44_RS30965 c6be6df1d9259914a66ed5a456bbef0c 598 Pfam PF06259 Alpha/beta hydrolase 342 509 1.4E-37 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 SMD44_RS05475 67a38ae33126fb99df0b38751c677fe3 295 Pfam PF13714 Phosphoenolpyruvate phosphomutase 35 263 2.7E-66 T 28-03-2018 SMD44_RS05475 67a38ae33126fb99df0b38751c677fe3 295 Gene3D G3DSA:3.20.20.60 28 286 4.2E-54 T 28-03-2018 SMD44_RS05475 67a38ae33126fb99df0b38751c677fe3 295 SUPERFAMILY SSF51621 30 284 2.74E-53 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 Pfam PF12796 Ankyrin repeats (3 copies) 14 109 2.6E-15 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 SUPERFAMILY SSF48403 13 140 1.15E-26 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 Gene3D G3DSA:1.25.40.20 1 148 2.6E-32 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 PRINTS PR01415 Ankyrin repeat signature 95 109 1.1E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 PRINTS PR01415 Ankyrin repeat signature 42 57 1.1E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 SMART SM00248 41 70 0.019 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 SMART SM00248 79 108 0.0032 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 SMART SM00248 114 144 400.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMD44_RS30105 b969e80d65547b19df15c63f4eb5510b 151 SMART SM00248 8 37 890.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMD44_RS10505 51a1dd890612500cfadb0920bc0fc78b 332 Pfam PF11271 Protein of unknown function (DUF3068) 5 306 4.1E-78 T 28-03-2018 IPR021424 Porin PorA SMD44_RS36335 8b8f07a72c73e180885a7cedf12f45c2 314 Gene3D G3DSA:1.10.3720.10 81 312 2.3E-45 T 28-03-2018 SMD44_RS36335 8b8f07a72c73e180885a7cedf12f45c2 314 SUPERFAMILY SSF161098 74 301 4.58E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS36335 8b8f07a72c73e180885a7cedf12f45c2 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 309 1.4E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS36335 8b8f07a72c73e180885a7cedf12f45c2 314 Gene3D G3DSA:1.20.58.370 10 63 8.2E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMD44_RS26430 3ae786d281287ebbb68fd49a243ad97d 193 SUPERFAMILY SSF55144 6 174 3.66E-29 T 28-03-2018 IPR009097 Cyclic phosphodiesterase SMD44_RS26430 3ae786d281287ebbb68fd49a243ad97d 193 Pfam PF13563 2'-5' RNA ligase superfamily 13 158 1.6E-19 T 28-03-2018 SMD44_RS26430 3ae786d281287ebbb68fd49a243ad97d 193 Gene3D G3DSA:3.90.1140.10 3 180 2.2E-29 T 28-03-2018 SMD44_RS04855 583dcba3dfb6084eb3d949b426665424 168 SUPERFAMILY SSF50475 15 164 1.86E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS04855 583dcba3dfb6084eb3d949b426665424 168 Gene3D G3DSA:2.30.110.10 2 167 4.6E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS04855 583dcba3dfb6084eb3d949b426665424 168 Pfam PF01613 Flavin reductase like domain 22 166 8.4E-37 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS04855 583dcba3dfb6084eb3d949b426665424 168 SMART SM00903 22 165 8.6E-51 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMD44_RS10525 ec0d3e3e9f25253fe66d6f8fdf46cd6c 165 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 36 146 1.7E-28 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 SMD44_RS10525 ec0d3e3e9f25253fe66d6f8fdf46cd6c 165 Pfam PF03061 Thioesterase superfamily 62 139 5.8E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMD44_RS10525 ec0d3e3e9f25253fe66d6f8fdf46cd6c 165 Gene3D G3DSA:3.10.129.10 22 159 7.0E-27 T 28-03-2018 SMD44_RS10525 ec0d3e3e9f25253fe66d6f8fdf46cd6c 165 SUPERFAMILY SSF54637 27 154 1.31E-28 T 28-03-2018 IPR029069 HotDog domain SMD44_RS25635 05e905e949700a55748efcb6419b1a92 134 Gene3D G3DSA:3.30.420.80 10 134 9.7E-48 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25635 05e905e949700a55748efcb6419b1a92 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.7E-59 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25635 05e905e949700a55748efcb6419b1a92 134 SUPERFAMILY SSF53137 19 134 4.8E-50 T 28-03-2018 SMD44_RS25635 05e905e949700a55748efcb6419b1a92 134 PIRSF PIRSF002131 4 134 4.1E-54 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25635 05e905e949700a55748efcb6419b1a92 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site SMD44_RS25635 05e905e949700a55748efcb6419b1a92 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 6 134 34.428 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25635 05e905e949700a55748efcb6419b1a92 134 Pfam PF00411 Ribosomal protein S11 24 133 1.4E-48 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMD44_RS26520 ab5f0c897c45512fa95320c6ec2a64e9 461 Pfam PF07690 Major Facilitator Superfamily 33 364 1.2E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS26520 ab5f0c897c45512fa95320c6ec2a64e9 461 SUPERFAMILY SSF103473 24 408 2.09E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26520 ab5f0c897c45512fa95320c6ec2a64e9 461 Gene3D G3DSA:1.20.1250.20 21 222 2.9E-18 T 28-03-2018 SMD44_RS26520 ab5f0c897c45512fa95320c6ec2a64e9 461 Gene3D G3DSA:1.20.1250.20 224 415 3.4E-9 T 28-03-2018 SMD44_RS28190 51f436a1225f5067176d4a8b2c0cc43e 978 Pfam PF03699 Uncharacterised protein family (UPF0182) 33 822 2.1E-280 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 SMD44_RS28190 51f436a1225f5067176d4a8b2c0cc43e 978 Hamap MF_01600 UPF0182 protein . 24 897 18.275 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 SMD44_RS12810 b31547e557fda15130d0b4e44139986d 419 SUPERFAMILY SSF53182 334 383 2.49E-24 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMD44_RS12810 b31547e557fda15130d0b4e44139986d 419 SUPERFAMILY SSF53182 165 306 2.49E-24 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMD44_RS12810 b31547e557fda15130d0b4e44139986d 419 Gene3D G3DSA:3.40.630.20 163 418 2.0E-35 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMD44_RS12930 43073375d879fda0a1cc54d83790fc40 499 Gene3D G3DSA:3.40.50.980 158 310 2.2E-41 T 28-03-2018 SMD44_RS12930 43073375d879fda0a1cc54d83790fc40 499 SUPERFAMILY SSF56801 10 496 2.75E-126 T 28-03-2018 SMD44_RS12930 43073375d879fda0a1cc54d83790fc40 499 Pfam PF00501 AMP-binding enzyme 15 404 6.7E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS12930 43073375d879fda0a1cc54d83790fc40 499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS12930 43073375d879fda0a1cc54d83790fc40 499 Gene3D G3DSA:2.30.38.10 311 397 1.5E-28 T 28-03-2018 SMD44_RS12930 43073375d879fda0a1cc54d83790fc40 499 Gene3D G3DSA:3.40.50.980 6 157 2.4E-30 T 28-03-2018 SMD44_RS12930 43073375d879fda0a1cc54d83790fc40 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 490 6.8E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS12930 43073375d879fda0a1cc54d83790fc40 499 Gene3D G3DSA:3.30.300.30 400 498 2.6E-29 T 28-03-2018 SMD44_RS10285 1b971051083f9bd3cca919232433c3a8 264 Pfam PF08241 Methyltransferase domain 48 139 1.1E-9 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS10285 1b971051083f9bd3cca919232433c3a8 264 SUPERFAMILY SSF53335 9 200 4.56E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS10285 1b971051083f9bd3cca919232433c3a8 264 Gene3D G3DSA:3.40.50.150 9 248 9.2E-21 T 28-03-2018 SMD44_RS14280 a6d7c0887bb661699bed5f3f400673a8 599 SUPERFAMILY SSF56300 372 533 5.22E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS14280 a6d7c0887bb661699bed5f3f400673a8 599 SUPERFAMILY SSF56300 132 217 5.22E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS14280 a6d7c0887bb661699bed5f3f400673a8 599 SUPERFAMILY SSF56300 276 303 5.22E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS14280 a6d7c0887bb661699bed5f3f400673a8 599 TIGRFAM TIGR03767 P_acnes_RR: metallophosphoesterase, PPA1498 family 96 599 1.1E-228 T 28-03-2018 IPR022506 Metallophosphoesterase, PPA1498 SMD44_RS14280 a6d7c0887bb661699bed5f3f400673a8 599 Pfam PF00149 Calcineurin-like phosphoesterase 132 499 1.3E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS14280 a6d7c0887bb661699bed5f3f400673a8 599 Gene3D G3DSA:3.60.21.10 127 545 2.4E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS07585 098768347aad12a3c58ecd6a252e83fd 274 Gene3D G3DSA:3.40.630.30 126 273 3.4E-25 T 28-03-2018 SMD44_RS07585 098768347aad12a3c58ecd6a252e83fd 274 Gene3D G3DSA:3.40.630.30 15 115 1.1E-10 T 28-03-2018 SMD44_RS07585 098768347aad12a3c58ecd6a252e83fd 274 SUPERFAMILY SSF55729 113 266 6.69E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS07585 098768347aad12a3c58ecd6a252e83fd 274 Pfam PF00583 Acetyltransferase (GNAT) family 180 262 2.0E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS07585 098768347aad12a3c58ecd6a252e83fd 274 Pfam PF00583 Acetyltransferase (GNAT) family 29 104 1.1E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS07585 098768347aad12a3c58ecd6a252e83fd 274 SUPERFAMILY SSF55729 25 109 1.54E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS07905 0d32693b5c98774639cb478283208046 382 SUPERFAMILY SSF55785 37 128 1.05E-8 T 28-03-2018 IPR000014 PAS domain SMD44_RS07905 0d32693b5c98774639cb478283208046 382 SMART SM00387 265 377 1.0E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07905 0d32693b5c98774639cb478283208046 382 Pfam PF08448 PAS fold 37 148 4.1E-6 T 28-03-2018 IPR013656 PAS fold-4 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 266 375 2.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07905 0d32693b5c98774639cb478283208046 382 Gene3D G3DSA:1.10.287.130 158 214 3.5E-14 T 28-03-2018 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 355 4.5E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 4.5E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 374 4.5E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 4.5E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 Gene3D G3DSA:3.30.565.10 215 377 1.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07905 0d32693b5c98774639cb478283208046 382 SUPERFAMILY SSF55874 210 375 8.64E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS07905 0d32693b5c98774639cb478283208046 382 Gene3D G3DSA:3.30.450.20 37 157 1.6E-14 T 28-03-2018 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 Pfam PF00512 His Kinase A (phospho-acceptor) domain 154 220 3.4E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 SUPERFAMILY SSF47384 139 221 7.85E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS07905 0d32693b5c98774639cb478283208046 382 SMART SM00388 152 220 1.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 Gene3D G3DSA:2.40.100.10 1 176 2.9E-60 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 170 3.8E-43 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 PIRSF PIRSF001467 1 176 3.9E-54 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 SUPERFAMILY SSF50891 6 171 1.04E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 9.6E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 9.6E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 9.6E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 9.6E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 9.6E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD44_RS21400 6fec47747579c90f5b25436f5e3b8234 177 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 SMD44_RS23560 e3e6b94f45b3cf9780cbd13c56ec3c68 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.0E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23560 e3e6b94f45b3cf9780cbd13c56ec3c68 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.0E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23560 e3e6b94f45b3cf9780cbd13c56ec3c68 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.0E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23560 e3e6b94f45b3cf9780cbd13c56ec3c68 126 SMART SM00422 1 69 2.5E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23560 e3e6b94f45b3cf9780cbd13c56ec3c68 126 Gene3D G3DSA:1.10.1660.10 1 54 5.0E-20 T 28-03-2018 SMD44_RS23560 e3e6b94f45b3cf9780cbd13c56ec3c68 126 SUPERFAMILY SSF46955 1 117 5.49E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS23560 e3e6b94f45b3cf9780cbd13c56ec3c68 126 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.8E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS23560 e3e6b94f45b3cf9780cbd13c56ec3c68 126 Gene3D G3DSA:1.10.1660.10 55 126 6.9E-11 T 28-03-2018 SMD44_RS03430 2558ec6232c3b6fd0f029a18e0d37dcc 149 Pfam PF10756 Bacterial PH domain 51 120 1.3E-5 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 SMD44_RS17745 a1f37ae840da5cded0087b11601b3925 179 Pfam PF07883 Cupin domain 55 116 9.7E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS17745 a1f37ae840da5cded0087b11601b3925 179 Gene3D G3DSA:2.60.120.10 11 149 4.1E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS17745 a1f37ae840da5cded0087b11601b3925 179 SUPERFAMILY SSF51182 34 157 1.62E-24 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS00870 1473e0c68cabacdcaa800e90f3844862 201 SUPERFAMILY SSF53597 6 194 7.2E-21 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS00870 1473e0c68cabacdcaa800e90f3844862 201 Gene3D G3DSA:3.40.430.10 2 187 7.6E-23 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS00870 1473e0c68cabacdcaa800e90f3844862 201 Pfam PF01872 RibD C-terminal domain 5 184 1.2E-21 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 Gene3D G3DSA:2.140.10.10 639 754 6.3E-17 T 28-03-2018 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 Gene3D G3DSA:1.10.510.10 97 288 2.2E-39 T 28-03-2018 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 SUPERFAMILY SSF50998 641 752 5.1E-18 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 SMART SM00564 505 537 31.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 SMART SM00564 644 676 0.097 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 SMART SM00564 684 716 0.52 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 SMART SM00564 458 489 85.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 Gene3D G3DSA:3.30.200.20 9 96 4.1E-13 T 28-03-2018 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 SUPERFAMILY SSF56112 11 261 1.09E-58 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 Gene3D G3DSA:2.140.10.10 500 638 2.1E-9 T 28-03-2018 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 Gene3D G3DSA:2.140.10.10 289 499 3.1E-9 T 28-03-2018 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 Pfam PF00069 Protein kinase domain 17 260 9.2E-36 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 42 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 SUPERFAMILY SSF50969 414 754 2.98E-13 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 Pfam PF13360 PQQ-like domain 390 555 1.4E-10 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 Pfam PF13360 PQQ-like domain 571 753 2.6E-13 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS24015 d30c4dfd66a5aa78eb8ba90047472545 759 SMART SM00220 14 263 3.7E-34 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS12365 37ca66d2dd69b248f27c423115ea017b 463 Pfam PF00534 Glycosyl transferases group 1 245 401 1.8E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS12365 37ca66d2dd69b248f27c423115ea017b 463 Pfam PF13439 Glycosyltransferase Family 4 27 231 1.5E-25 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS12365 37ca66d2dd69b248f27c423115ea017b 463 Gene3D G3DSA:3.40.50.2000 8 244 9.4E-13 T 28-03-2018 SMD44_RS12365 37ca66d2dd69b248f27c423115ea017b 463 SUPERFAMILY SSF53756 15 424 1.23E-80 T 28-03-2018 SMD44_RS12365 37ca66d2dd69b248f27c423115ea017b 463 Gene3D G3DSA:3.40.50.2000 245 414 8.2E-40 T 28-03-2018 SMD44_RS14570 be9d08f4c654977971f89c64727d9f59 206 Pfam PF10935 Protein of unknown function (DUF2637) 11 118 2.0E-15 T 28-03-2018 IPR021235 Protein of unknown function DUF2637 SMD44_RS40520 e445af93d720cb6478432ecbc5b2b276 389 Gene3D G3DSA:1.50.10.10 45 388 2.6E-56 T 28-03-2018 SMD44_RS40520 e445af93d720cb6478432ecbc5b2b276 389 Pfam PF07470 Glycosyl Hydrolase Family 88 71 387 4.3E-65 T 28-03-2018 IPR010905 Glycosyl hydrolase, family 88 SMD44_RS40520 e445af93d720cb6478432ecbc5b2b276 389 SUPERFAMILY SSF48208 69 387 1.36E-39 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 Gene3D G3DSA:2.60.40.1180 839 898 1.3E-22 T 28-03-2018 SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 Gene3D G3DSA:2.60.40.10 161 262 3.4E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 SUPERFAMILY SSF81296 33 160 2.66E-30 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 SUPERFAMILY SSF51011 806 896 1.22E-21 T 28-03-2018 SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 40 897 1.9E-302 T 28-03-2018 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 170 248 6.4E-8 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 SUPERFAMILY SSF51445 261 803 2.72E-116 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 Gene3D G3DSA:3.20.20.80 263 838 5.9E-81 T 28-03-2018 SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 Gene3D G3DSA:2.60.40.1130 40 159 3.2E-41 T 28-03-2018 SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 Pfam PF11852 Domain of unknown function (DUF3372) 746 896 2.6E-44 T 28-03-2018 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal SMD44_RS05275 aafe99cbd8d36b39680ac7d3b79d93c5 898 SUPERFAMILY SSF81296 168 265 1.72E-18 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS14520 2600797a317e9e15bc2935a23aed838a 332 SUPERFAMILY SSF53335 36 220 4.18E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS14520 2600797a317e9e15bc2935a23aed838a 332 Gene3D G3DSA:3.40.50.150 27 265 5.1E-45 T 28-03-2018 SMD44_RS14520 2600797a317e9e15bc2935a23aed838a 332 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 85 231 1.1E-25 T 28-03-2018 SMD44_RS25055 9ecf2450edf9782a0bd8d70c441ef50a 462 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 26 363 24.154 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25055 9ecf2450edf9782a0bd8d70c441ef50a 462 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 72 87 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25055 9ecf2450edf9782a0bd8d70c441ef50a 462 Pfam PF00146 NADH dehydrogenase 33 356 2.6E-122 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25055 9ecf2450edf9782a0bd8d70c441ef50a 462 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 239 252 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS15730 1ca3ad3ff7b92c86be827283993443fb 569 Pfam PF10708 Protein of unknown function (DUF2510) 16 45 6.4E-8 T 28-03-2018 IPR018929 Domain of unknown function DUF2510 SMD44_RS15730 1ca3ad3ff7b92c86be827283993443fb 569 Pfam PF06271 RDD family 413 564 6.4E-25 T 28-03-2018 IPR010432 RDD SMD44_RS31510 2b33e9cb2d810d4faa44b6784dd9961b 701 Gene3D G3DSA:1.50.10.10 274 655 3.9E-25 T 28-03-2018 SMD44_RS31510 2b33e9cb2d810d4faa44b6784dd9961b 701 SUPERFAMILY SSF48208 275 686 7.91E-25 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS31510 2b33e9cb2d810d4faa44b6784dd9961b 701 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 71 243 1.7E-17 T 28-03-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal SMD44_RS29270 87c4a9902a15825385d285fc619e2380 472 PRINTS PR00173 Glutamate-aspartate symporter signature 342 361 8.2E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS29270 87c4a9902a15825385d285fc619e2380 472 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 8.2E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS29270 87c4a9902a15825385d285fc619e2380 472 PRINTS PR00173 Glutamate-aspartate symporter signature 24 44 8.2E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS29270 87c4a9902a15825385d285fc619e2380 472 PRINTS PR00173 Glutamate-aspartate symporter signature 307 333 8.2E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS29270 87c4a9902a15825385d285fc619e2380 472 PRINTS PR00173 Glutamate-aspartate symporter signature 91 116 8.2E-26 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS29270 87c4a9902a15825385d285fc619e2380 472 SUPERFAMILY SSF118215 26 416 1.83E-104 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS29270 87c4a9902a15825385d285fc619e2380 472 Pfam PF00375 Sodium:dicarboxylate symporter family 26 415 1.9E-99 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS29270 87c4a9902a15825385d285fc619e2380 472 Gene3D G3DSA:1.10.3860.10 19 423 1.3E-105 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 Gene3D G3DSA:3.40.30.10 1 110 2.4E-34 T 28-03-2018 SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 Pfam PF00085 Thioredoxin 6 105 1.5E-32 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 PRINTS PR00421 Thioredoxin family signature 72 83 9.2E-8 T 28-03-2018 SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 PRINTS PR00421 Thioredoxin family signature 32 41 9.2E-8 T 28-03-2018 SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 PRINTS PR00421 Thioredoxin family signature 24 32 9.2E-8 T 28-03-2018 SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 SUPERFAMILY SSF52833 5 108 4.33E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 PIRSF PIRSF000077 2 108 4.3E-43 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD44_RS21070 01be9a18971c881d8fdda131cd7c6b23 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 1.7E-36 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD44_RS43125 a0942d906aeb0c8a2084f995b0f1701a 206 Pfam PF13563 2'-5' RNA ligase superfamily 51 184 3.2E-7 T 28-03-2018 SMD44_RS43125 a0942d906aeb0c8a2084f995b0f1701a 206 Gene3D G3DSA:3.90.1140.10 22 206 9.6E-12 T 28-03-2018 SMD44_RS43125 a0942d906aeb0c8a2084f995b0f1701a 206 SUPERFAMILY SSF55144 26 185 2.88E-10 T 28-03-2018 IPR009097 Cyclic phosphodiesterase SMD44_RS22025 34579ae7aa93913dd7c25c48beddc4c1 669 Pfam PF13515 Fusaric acid resistance protein-like 383 503 2.8E-20 T 28-03-2018 SMD44_RS22025 34579ae7aa93913dd7c25c48beddc4c1 669 Pfam PF12805 FUSC-like inner membrane protein yccS 86 237 1.2E-10 T 28-03-2018 IPR032692 Integral membrane protein YccS, N-terminal SMD44_RS08605 921e2c4d25d9b60f614665c0ca11be80 295 SUPERFAMILY SSF47413 30 77 1.91E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS08605 921e2c4d25d9b60f614665c0ca11be80 295 Gene3D G3DSA:1.10.260.40 1 87 7.0E-15 T 28-03-2018 SMD44_RS08605 921e2c4d25d9b60f614665c0ca11be80 295 Pfam PF13560 Helix-turn-helix domain 7 85 2.2E-15 T 28-03-2018 SMD44_RS08605 921e2c4d25d9b60f614665c0ca11be80 295 SMART SM00530 10 82 0.0015 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS28955 77378963cbd279074c2def7a4f4abdd5 107 Gene3D G3DSA:3.30.750.24 3 96 7.7E-15 T 28-03-2018 IPR002645 STAS domain SMD44_RS28955 77378963cbd279074c2def7a4f4abdd5 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 96 8.2E-16 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD44_RS28955 77378963cbd279074c2def7a4f4abdd5 107 Pfam PF13466 STAS domain 10 89 2.5E-15 T 28-03-2018 IPR002645 STAS domain SMD44_RS28955 77378963cbd279074c2def7a4f4abdd5 107 SUPERFAMILY SSF52091 2 96 1.79E-21 T 28-03-2018 IPR002645 STAS domain SMD44_RS09630 41c20b95ee85070232a4a01fbfa06e34 494 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 190 9.5E-20 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMD44_RS09630 41c20b95ee85070232a4a01fbfa06e34 494 SUPERFAMILY SSF52317 299 492 2.93E-33 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS09630 41c20b95ee85070232a4a01fbfa06e34 494 Gene3D G3DSA:3.40.50.880 257 449 7.7E-29 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS09630 41c20b95ee85070232a4a01fbfa06e34 494 Gene3D G3DSA:3.40.50.300 45 192 2.6E-30 T 28-03-2018 SMD44_RS09630 41c20b95ee85070232a4a01fbfa06e34 494 Gene3D G3DSA:3.40.50.300 3 44 2.8E-6 T 28-03-2018 SMD44_RS09630 41c20b95ee85070232a4a01fbfa06e34 494 SUPERFAMILY SSF52540 4 196 9.75E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09630 41c20b95ee85070232a4a01fbfa06e34 494 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 300 481 1.5E-24 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SMD44_RS09630 41c20b95ee85070232a4a01fbfa06e34 494 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 2 482 42.262 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 SMD44_RS41730 aaf43d2758ded6807cca02c70031a8b8 299 Pfam PF08443 RimK-like ATP-grasp domain 101 273 3.0E-33 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 SMD44_RS41730 aaf43d2758ded6807cca02c70031a8b8 299 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 55 273 1.4E-49 T 28-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 SMD44_RS41730 aaf43d2758ded6807cca02c70031a8b8 299 SUPERFAMILY SSF56059 102 288 3.18E-27 T 28-03-2018 SMD44_RS41730 aaf43d2758ded6807cca02c70031a8b8 299 Gene3D G3DSA:3.30.1490.20 106 173 7.0E-8 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS41730 aaf43d2758ded6807cca02c70031a8b8 299 Gene3D G3DSA:3.30.470.20 174 278 1.7E-24 T 28-03-2018 SMD44_RS41730 aaf43d2758ded6807cca02c70031a8b8 299 Gene3D G3DSA:3.40.50.20 2 105 7.6E-16 T 28-03-2018 SMD44_RS11770 bddf329aa41a17426fc68bda31de6066 206 SMART SM00862 126 200 5.3E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS11770 bddf329aa41a17426fc68bda31de6066 206 Gene3D G3DSA:1.10.10.10 99 206 2.7E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11770 bddf329aa41a17426fc68bda31de6066 206 Pfam PF00486 Transcriptional regulatory protein, C terminal 126 199 4.4E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS11770 bddf329aa41a17426fc68bda31de6066 206 SUPERFAMILY SSF46894 110 200 2.17E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS43620 01deedd8ab0f4b3eea553a0c8fc1388a 133 Gene3D G3DSA:1.10.260.40 15 53 1.3E-6 T 28-03-2018 SMD44_RS43620 01deedd8ab0f4b3eea553a0c8fc1388a 133 Gene3D G3DSA:1.10.10.60 1 14 0.47 T 28-03-2018 SMD44_RS43620 01deedd8ab0f4b3eea553a0c8fc1388a 133 Pfam PF13560 Helix-turn-helix domain 54 110 9.5E-12 T 28-03-2018 SMD44_RS43620 01deedd8ab0f4b3eea553a0c8fc1388a 133 SMART SM00530 1 44 31.0 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS43620 01deedd8ab0f4b3eea553a0c8fc1388a 133 SMART SM00530 53 108 3.2E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS43620 01deedd8ab0f4b3eea553a0c8fc1388a 133 SUPERFAMILY SSF47413 4 49 2.25E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS43620 01deedd8ab0f4b3eea553a0c8fc1388a 133 SUPERFAMILY SSF47413 54 108 4.35E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS43620 01deedd8ab0f4b3eea553a0c8fc1388a 133 Gene3D G3DSA:1.10.260.40 54 124 2.9E-11 T 28-03-2018 SMD44_RS26385 b71acf0c1027a04500713da6547e23a5 228 Gene3D G3DSA:3.40.50.360 36 227 1.2E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS26385 b71acf0c1027a04500713da6547e23a5 228 SUPERFAMILY SSF52218 35 198 4.19E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS26385 b71acf0c1027a04500713da6547e23a5 228 Pfam PF02525 Flavodoxin-like fold 36 196 3.5E-37 T 28-03-2018 IPR003680 Flavodoxin-like fold SMD44_RS16830 c9c93572716ee560f428757ac99b25a4 703 Gene3D G3DSA:3.90.220.20 570 679 0.001 T 28-03-2018 SMD44_RS16830 c9c93572716ee560f428757ac99b25a4 703 Gene3D G3DSA:3.40.50.150 172 450 7.9E-30 T 28-03-2018 SMD44_RS16830 c9c93572716ee560f428757ac99b25a4 703 Pfam PF02384 N-6 DNA Methylase 157 396 3.0E-33 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMD44_RS16830 c9c93572716ee560f428757ac99b25a4 703 SUPERFAMILY SSF53335 156 456 2.22E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS16830 c9c93572716ee560f428757ac99b25a4 703 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 300 324 6.6E-11 T 28-03-2018 SMD44_RS16830 c9c93572716ee560f428757ac99b25a4 703 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 266 278 6.6E-11 T 28-03-2018 SMD44_RS16830 c9c93572716ee560f428757ac99b25a4 703 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 197 211 6.6E-11 T 28-03-2018 SMD44_RS40125 a45a2d393adde3a1f9e1b71f77419ae7 352 Pfam PF00656 Caspase domain 6 190 5.7E-8 T 28-03-2018 SMD44_RS40125 a45a2d393adde3a1f9e1b71f77419ae7 352 Gene3D G3DSA:3.40.50.1460 2 265 6.3E-26 T 28-03-2018 SMD44_RS27975 4757b95d91f62d53db6f29ec080bf79f 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS27975 4757b95d91f62d53db6f29ec080bf79f 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS27975 4757b95d91f62d53db6f29ec080bf79f 213 SUPERFAMILY SSF48498 92 204 2.1E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS27975 4757b95d91f62d53db6f29ec080bf79f 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 6.2E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS27975 4757b95d91f62d53db6f29ec080bf79f 213 Gene3D G3DSA:1.10.10.60 3 58 3.9E-21 T 28-03-2018 SMD44_RS27975 4757b95d91f62d53db6f29ec080bf79f 213 Gene3D G3DSA:1.10.10.60 59 79 5.0E-14 T 28-03-2018 SMD44_RS27975 4757b95d91f62d53db6f29ec080bf79f 213 SUPERFAMILY SSF46689 12 94 5.49E-22 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS27975 4757b95d91f62d53db6f29ec080bf79f 213 Gene3D G3DSA:1.10.357.10 80 205 7.0E-21 T 28-03-2018 SMD44_RS36910 631ca0c1b6affa2980d01922c8c4c2c8 317 SUPERFAMILY SSF52151 201 287 7.59E-32 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36910 631ca0c1b6affa2980d01922c8c4c2c8 317 SUPERFAMILY SSF52151 9 130 7.59E-32 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS36910 631ca0c1b6affa2980d01922c8c4c2c8 317 Gene3D G3DSA:3.40.366.10 2 309 8.2E-31 T 28-03-2018 SMD44_RS40810 dcb4d6e5291362a0a9bcd75874495112 105 SUPERFAMILY SSF102705 4 103 5.49E-17 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMD44_RS40810 dcb4d6e5291362a0a9bcd75874495112 105 Gene3D G3DSA:3.30.70.120 1 105 8.8E-30 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMD44_RS05210 f8b80893ac7797a837df4a5760fcc05f 297 Gene3D G3DSA:1.10.1040.10 163 294 3.3E-10 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS05210 f8b80893ac7797a837df4a5760fcc05f 297 Gene3D G3DSA:3.40.50.720 1 162 2.5E-31 T 28-03-2018 SMD44_RS05210 f8b80893ac7797a837df4a5760fcc05f 297 PIRSF PIRSF000103 1 297 1.0E-40 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS05210 f8b80893ac7797a837df4a5760fcc05f 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 160 4.6E-25 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS05210 f8b80893ac7797a837df4a5760fcc05f 297 SUPERFAMILY SSF51735 9 159 3.29E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 SUPERFAMILY SSF51126 63 367 3.88E-22 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 SMART SM00710 165 187 1800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 SMART SM00710 249 271 5.9 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 SMART SM00710 344 365 1000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 SMART SM00710 213 248 1100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 SMART SM00710 296 333 35.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 SMART SM00710 273 295 970.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 Pfam PF13229 Right handed beta helix region 166 329 7.3E-11 T 28-03-2018 SMD44_RS38830 c4d9298f55a7b931c6f7787992c39e1b 512 Gene3D G3DSA:2.160.20.10 73 508 8.2E-37 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS09945 758829ee9b0b2f65f773607574c4027e 408 Gene3D G3DSA:2.140.10.30 285 403 4.6E-5 T 28-03-2018 SMD44_RS09945 758829ee9b0b2f65f773607574c4027e 408 Gene3D G3DSA:2.130.10.10 51 282 8.7E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS09945 758829ee9b0b2f65f773607574c4027e 408 SUPERFAMILY SSF82171 159 387 8.24E-14 T 28-03-2018 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 68 155 2.9E-16 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 Gene3D G3DSA:1.10.10.60 2 61 8.4E-15 T 28-03-2018 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 3.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 PRINTS PR00400 Tetracycline repressor protein signature 21 44 3.4E-22 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 PRINTS PR00400 Tetracycline repressor protein signature 129 148 3.4E-22 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 PRINTS PR00400 Tetracycline repressor protein signature 95 118 3.4E-22 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 PRINTS PR00400 Tetracycline repressor protein signature 75 94 3.4E-22 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 SUPERFAMILY SSF46689 4 63 8.21E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 SUPERFAMILY SSF48498 69 187 3.56E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS39930 da6d94ae4a7bd299ddee702b1ac41755 199 Gene3D G3DSA:1.10.357.10 62 190 3.3E-19 T 28-03-2018 SMD44_RS20510 b88715c0510b4ded9ac97aa19ba21c97 223 Pfam PF13671 AAA domain 55 199 9.9E-20 T 28-03-2018 SMD44_RS20510 b88715c0510b4ded9ac97aa19ba21c97 223 SUPERFAMILY SSF52540 47 213 4.43E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20510 b88715c0510b4ded9ac97aa19ba21c97 223 Gene3D G3DSA:3.40.50.300 63 222 4.7E-19 T 28-03-2018 SMD44_RS20510 b88715c0510b4ded9ac97aa19ba21c97 223 Gene3D G3DSA:3.40.50.300 31 62 1.9E-6 T 28-03-2018 SMD44_RS32545 5790062d2570b31773923387ec69c554 219 SUPERFAMILY SSF53300 3 183 2.04E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS32545 5790062d2570b31773923387ec69c554 219 Gene3D G3DSA:3.40.50.410 3 203 1.6E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS17970 97a83ddc64fc96a3e445aa6e256c5033 239 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 198 239 3.3E-10 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS17970 97a83ddc64fc96a3e445aa6e256c5033 239 SUPERFAMILY SSF50475 40 239 9.62E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS17970 97a83ddc64fc96a3e445aa6e256c5033 239 PIRSF PIRSF000190 28 239 3.5E-53 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS17970 97a83ddc64fc96a3e445aa6e256c5033 239 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 61 140 9.3E-18 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS17970 97a83ddc64fc96a3e445aa6e256c5033 239 Gene3D G3DSA:2.30.110.10 40 239 1.0E-53 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS17040 30c2b11bea9027197a8c7366b29885ce 637 Gene3D G3DSA:2.140.10.10 48 397 6.7E-11 T 28-03-2018 SMD44_RS17040 30c2b11bea9027197a8c7366b29885ce 637 Gene3D G3DSA:2.140.10.10 398 613 5.6E-10 T 28-03-2018 SMD44_RS17040 30c2b11bea9027197a8c7366b29885ce 637 SUPERFAMILY SSF50998 171 179 1.61E-15 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS17040 30c2b11bea9027197a8c7366b29885ce 637 SUPERFAMILY SSF50998 263 471 1.61E-15 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS17040 30c2b11bea9027197a8c7366b29885ce 637 SUPERFAMILY SSF50998 410 609 5.89E-7 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS17040 30c2b11bea9027197a8c7366b29885ce 637 Pfam PF13360 PQQ-like domain 245 381 1.2E-8 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 Pfam PF00005 ABC transporter 34 179 1.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 Pfam PF00005 ABC transporter 285 441 5.0E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 SUPERFAMILY SSF52540 258 500 1.52E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 Gene3D G3DSA:3.40.50.300 5 244 3.3E-47 T 28-03-2018 SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 Gene3D G3DSA:3.40.50.300 263 568 3.3E-36 T 28-03-2018 SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 SMART SM00382 42 227 1.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 SMART SM00382 294 490 7.3 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS26775 1e42be133aeacff3f3d83377d708b520 568 SUPERFAMILY SSF52540 18 236 9.25E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07180 a322074a255d38cd7c3c48b534600599 380 SUPERFAMILY SSF88659 91 149 1.9E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS07180 a322074a255d38cd7c3c48b534600599 380 SUPERFAMILY SSF88946 3 85 5.1E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS07180 a322074a255d38cd7c3c48b534600599 380 Gene3D G3DSA:1.10.1740.10 3 73 3.0E-16 T 28-03-2018 SMD44_RS07180 a322074a255d38cd7c3c48b534600599 380 Gene3D G3DSA:1.10.10.10 74 152 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07180 a322074a255d38cd7c3c48b534600599 380 Pfam PF08281 Sigma-70, region 4 98 148 4.4E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS07180 a322074a255d38cd7c3c48b534600599 380 Pfam PF04542 Sigma-70 region 2 5 68 3.4E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS32285 80063daecb2b3ad8363ea956ac3c9c0f 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 302 4.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS32285 80063daecb2b3ad8363ea956ac3c9c0f 308 SUPERFAMILY SSF161098 32 308 7.38E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS32285 80063daecb2b3ad8363ea956ac3c9c0f 308 Gene3D G3DSA:1.10.3720.10 27 296 1.1E-43 T 28-03-2018 SMD44_RS16735 8426520cc9f912b0377975c66cb69bda 307 Pfam PF12811 Bax inhibitor 1 like 5 304 4.3E-81 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 SMD44_RS16735 8426520cc9f912b0377975c66cb69bda 307 PIRSF PIRSF009160 1 307 1.2E-98 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 SMD44_RS34565 bc6dae7494950e1615cec988f152c89e 86 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 29 85 3.0E-6 T 28-03-2018 IPR008792 Coenzyme PQQ synthesis D SMD44_RS34565 bc6dae7494950e1615cec988f152c89e 86 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 7 86 1.1E-17 T 28-03-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 SMD44_RS12140 5b6b6d531efe141fd0787db3cddeee77 286 Pfam PF13649 Methyltransferase domain 68 169 2.2E-10 T 28-03-2018 SMD44_RS12140 5b6b6d531efe141fd0787db3cddeee77 286 Gene3D G3DSA:3.40.50.150 36 285 2.6E-36 T 28-03-2018 SMD44_RS12140 5b6b6d531efe141fd0787db3cddeee77 286 SUPERFAMILY SSF53335 49 271 9.28E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS06730 30d2ecc4b64fe038777a0c8eac6b952e 1216 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 190 5.4E-57 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 SMD44_RS06730 30d2ecc4b64fe038777a0c8eac6b952e 1216 Pfam PF01968 Hydantoinase/oxoprolinase 210 497 1.5E-111 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 SMD44_RS06730 30d2ecc4b64fe038777a0c8eac6b952e 1216 Pfam PF02538 Hydantoinase B/oxoprolinase 692 1199 1.1E-201 T 28-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 SMD44_RS37625 3438c40af829d1c198cfa4443d7b149e 115 Pfam PF09947 Uncharacterized protein conserved in archaea (DUF2180) 49 111 4.7E-9 T 28-03-2018 IPR017211 Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427 SMD44_RS14050 69938198c7f76d3efd40224b219444ce 724 Gene3D G3DSA:3.90.1310.10 29 257 6.7E-44 T 28-03-2018 SMD44_RS14050 69938198c7f76d3efd40224b219444ce 724 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 661 6.4E-181 T 28-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 SMD44_RS14050 69938198c7f76d3efd40224b219444ce 724 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 246 1.1E-39 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMD44_RS14050 69938198c7f76d3efd40224b219444ce 724 SUPERFAMILY SSF56601 213 459 2.33E-84 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS14050 69938198c7f76d3efd40224b219444ce 724 SUPERFAMILY SSF56601 516 665 2.33E-84 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS14050 69938198c7f76d3efd40224b219444ce 724 Gene3D G3DSA:3.40.710.10 258 667 2.5E-82 T 28-03-2018 SMD44_RS14050 69938198c7f76d3efd40224b219444ce 724 SUPERFAMILY SSF56519 53 261 1.96E-37 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMD44_RS14050 69938198c7f76d3efd40224b219444ce 724 Pfam PF00905 Penicillin binding protein transpeptidase domain 298 658 8.6E-85 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 SUPERFAMILY SSF51126 40 286 1.52E-32 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 SMART SM00710 151 179 11.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 SMART SM00710 212 234 2100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 SMART SM00710 241 263 2000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 SMART SM00710 127 149 1100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 SMART SM00710 105 126 140.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 SMART SM00710 187 210 4900.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 Pfam PF13229 Right handed beta helix region 92 242 7.7E-11 T 28-03-2018 SMD44_RS10485 f62cdcfaf6bf9a6d4a69189052841a67 324 Gene3D G3DSA:2.160.20.10 5 320 3.1E-34 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 Gene3D G3DSA:1.20.140.10 225 384 1.0E-63 T 28-03-2018 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 3.5E-27 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 SUPERFAMILY SSF47203 234 384 1.45E-58 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 Gene3D G3DSA:1.10.540.10 3 126 1.1E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 Gene3D G3DSA:2.40.110.10 127 224 1.0E-38 T 28-03-2018 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 124 5.7E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 PIRSF PIRSF016578 8 97 1.4E-7 T 28-03-2018 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 PIRSF PIRSF016578 131 382 7.5E-20 T 28-03-2018 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 SUPERFAMILY SSF56645 12 247 3.01E-78 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS16530 d77dcc6947dca7c854102554edf6fc6a 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 384 1.2E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 Gene3D G3DSA:1.10.287.130 310 365 1.0E-13 T 28-03-2018 SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 Pfam PF17203 Single cache domain 3 22 161 5.0E-32 T 28-03-2018 IPR033463 Single cache domain 3 SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 Gene3D G3DSA:3.30.565.10 368 526 7.1E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 516 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 463 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 497 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 Gene3D G3DSA:3.30.450.20 20 162 9.6E-29 T 28-03-2018 SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 SMART SM00387 410 519 3.9E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 SUPERFAMILY SSF55785 198 301 2.51E-6 T 28-03-2018 IPR000014 PAS domain SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 SUPERFAMILY SSF103190 23 158 2.0E-35 T 28-03-2018 IPR029151 Periplasmic sensor domain-like SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 413 518 1.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 SUPERFAMILY SSF55874 381 519 1.05E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 SUPERFAMILY SSF55890 319 380 2.75E-5 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 SMD44_RS29265 21c2fc523bab52b50480ef73388e35f3 536 Gene3D G3DSA:3.30.450.20 192 309 4.7E-13 T 28-03-2018 SMD44_RS24970 f1684dbc1dc0f725a4f27d35dd7c3b1c 116 Gene3D G3DSA:3.20.20.140 1 112 3.3E-4 T 28-03-2018 SMD44_RS37970 e84ce87d2eba5b936cfa07581090cd99 251 Pfam PF00012 Hsp70 protein 56 124 5.2E-7 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD44_RS37970 e84ce87d2eba5b936cfa07581090cd99 251 SUPERFAMILY SSF53067 48 96 3.37E-6 T 28-03-2018 SMD44_RS37970 e84ce87d2eba5b936cfa07581090cd99 251 Gene3D G3DSA:3.30.420.40 34 121 2.0E-11 T 28-03-2018 SMD44_RS23640 96ef1e2d4aeaf15b23310eb5efba3427 214 SUPERFAMILY SSF46785 4 179 1.36E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23640 96ef1e2d4aeaf15b23310eb5efba3427 214 Gene3D G3DSA:1.10.10.10 1 97 2.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23640 96ef1e2d4aeaf15b23310eb5efba3427 214 Pfam PF03551 Transcriptional regulator PadR-like family 8 84 1.3E-11 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS20445 710342ae6b897b46afc7dcfbe3f43ab8 163 Gene3D G3DSA:3.10.129.10 2 150 7.0E-26 T 28-03-2018 SMD44_RS20445 710342ae6b897b46afc7dcfbe3f43ab8 163 Pfam PF01575 MaoC like domain 16 113 1.3E-6 T 28-03-2018 IPR002539 MaoC-like domain SMD44_RS20445 710342ae6b897b46afc7dcfbe3f43ab8 163 SUPERFAMILY SSF54637 8 150 2.69E-18 T 28-03-2018 IPR029069 HotDog domain SMD44_RS04765 15336c1a9bc40a26c2977699b2434548 500 SUPERFAMILY SSF56349 123 434 2.0E-39 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS04765 15336c1a9bc40a26c2977699b2434548 500 Pfam PF00589 Phage integrase family 226 431 3.6E-12 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS04765 15336c1a9bc40a26c2977699b2434548 500 Gene3D G3DSA:1.10.150.130 102 214 1.9E-12 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS04765 15336c1a9bc40a26c2977699b2434548 500 Gene3D G3DSA:1.10.443.10 215 448 1.6E-27 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS08315 1314a789c834e95eb5dfd7314c8a8f7a 332 SUPERFAMILY SSF144083 267 329 4.18E-19 T 28-03-2018 SMD44_RS08315 1314a789c834e95eb5dfd7314c8a8f7a 332 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 33 332 6.8E-61 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 SMD44_RS08315 1314a789c834e95eb5dfd7314c8a8f7a 332 Pfam PF01544 CorA-like Mg2+ transporter protein 32 328 2.6E-64 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD44_RS08315 1314a789c834e95eb5dfd7314c8a8f7a 332 Gene3D G3DSA:1.20.58.340 140 264 2.3E-31 T 28-03-2018 SMD44_RS08315 1314a789c834e95eb5dfd7314c8a8f7a 332 SUPERFAMILY SSF143865 3 265 6.41E-65 T 28-03-2018 SMD44_RS08315 1314a789c834e95eb5dfd7314c8a8f7a 332 Gene3D G3DSA:1.20.58.340 265 332 4.0E-20 T 28-03-2018 SMD44_RS08315 1314a789c834e95eb5dfd7314c8a8f7a 332 Gene3D G3DSA:3.30.460.20 1 138 1.2E-35 T 28-03-2018 SMD44_RS23930 086ad8230a09ed96b66626814fb77d1f 237 SMART SM00862 164 235 3.1E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS23930 086ad8230a09ed96b66626814fb77d1f 237 SUPERFAMILY SSF52172 3 124 1.99E-40 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS23930 086ad8230a09ed96b66626814fb77d1f 237 Pfam PF00072 Response regulator receiver domain 7 116 2.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23930 086ad8230a09ed96b66626814fb77d1f 237 SUPERFAMILY SSF46894 139 235 1.56E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS23930 086ad8230a09ed96b66626814fb77d1f 237 SMART SM00448 5 115 1.8E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS23930 086ad8230a09ed96b66626814fb77d1f 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 235 1.9E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS23930 086ad8230a09ed96b66626814fb77d1f 237 Gene3D G3DSA:3.40.50.2300 2 137 4.2E-37 T 28-03-2018 SMD44_RS23930 086ad8230a09ed96b66626814fb77d1f 237 Gene3D G3DSA:1.10.10.10 138 237 8.7E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15680 cf40c366ce667d37c6cfbb19f0d172dd 500 Pfam PF00324 Amino acid permease 38 471 4.9E-114 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD44_RS15680 cf40c366ce667d37c6cfbb19f0d172dd 500 ProSitePatterns PS00218 Amino acid permeases signature. 62 92 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD44_RS15680 cf40c366ce667d37c6cfbb19f0d172dd 500 PIRSF PIRSF006060 15 490 4.9E-67 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS36390 2d4185dced6a4811120d96c9aab0ac7d 503 PIRSF PIRSF006060 6 502 5.9E-62 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS36390 2d4185dced6a4811120d96c9aab0ac7d 503 Pfam PF13520 Amino acid permease 33 468 1.3E-60 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS36390 2d4185dced6a4811120d96c9aab0ac7d 503 ProSitePatterns PS00218 Amino acid permeases signature. 60 91 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD44_RS27440 c919e76b97247baa5ddf517d1a9db217 177 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 3 175 2.9E-93 T 28-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS27440 c919e76b97247baa5ddf517d1a9db217 177 Gene3D G3DSA:1.20.1290.10 1 175 3.8E-46 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS27440 c919e76b97247baa5ddf517d1a9db217 177 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 177 85.728 T 28-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS27440 c919e76b97247baa5ddf517d1a9db217 177 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 112 160 1.6E-20 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS27440 c919e76b97247baa5ddf517d1a9db217 177 SUPERFAMILY SSF69118 3 169 9.81E-50 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD44_RS27440 c919e76b97247baa5ddf517d1a9db217 177 Pfam PF02627 Carboxymuconolactone decarboxylase family 94 167 9.5E-16 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD44_RS25280 7252073c8e6a2b55f7ec04710567fa5c 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS25280 7252073c8e6a2b55f7ec04710567fa5c 200 Gene3D G3DSA:3.30.70.20 103 173 2.2E-6 T 28-03-2018 SMD44_RS25280 7252073c8e6a2b55f7ec04710567fa5c 200 Gene3D G3DSA:3.30.70.20 63 102 1.3E-10 T 28-03-2018 SMD44_RS25280 7252073c8e6a2b55f7ec04710567fa5c 200 SUPERFAMILY SSF54862 30 143 2.72E-19 T 28-03-2018 SMD44_RS25280 7252073c8e6a2b55f7ec04710567fa5c 200 Pfam PF00037 4Fe-4S binding domain 95 115 8.5E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS25280 7252073c8e6a2b55f7ec04710567fa5c 200 Gene3D G3DSA:3.30.70.20 18 62 5.9E-5 T 28-03-2018 SMD44_RS25280 7252073c8e6a2b55f7ec04710567fa5c 200 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 3 170 24.178 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS19115 f086e071bdd6d08fbcb6357543328608 250 SUPERFAMILY SSF50969 3 185 5.49E-8 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMD44_RS19115 f086e071bdd6d08fbcb6357543328608 250 Gene3D G3DSA:2.130.10.10 17 227 3.2E-6 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS36010 ec8c058f54dbbb8bdd492d49969a5fe6 323 Gene3D G3DSA:3.40.50.1820 3 323 1.9E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36010 ec8c058f54dbbb8bdd492d49969a5fe6 323 SUPERFAMILY SSF53474 8 321 3.35E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36010 ec8c058f54dbbb8bdd492d49969a5fe6 323 Pfam PF12146 Serine aminopeptidase, S33 36 306 1.2E-48 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 SMD44_RS43600 4c99d36d7029b5296d8f229c986562cb 148 Gene3D G3DSA:1.20.144.10 81 147 1.1E-6 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS43600 4c99d36d7029b5296d8f229c986562cb 148 SUPERFAMILY SSF48317 38 145 6.54E-6 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS23625 c890b791d9316c1230e448a5adc8b980 307 Pfam PF13560 Helix-turn-helix domain 16 78 1.9E-13 T 28-03-2018 SMD44_RS23625 c890b791d9316c1230e448a5adc8b980 307 SUPERFAMILY SSF47413 13 69 4.44E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS23625 c890b791d9316c1230e448a5adc8b980 307 Gene3D G3DSA:1.10.260.40 15 290 2.8E-11 T 28-03-2018 SMD44_RS26130 b59358be7f176e529401e37e297abe88 256 Gene3D G3DSA:3.40.1000.10 93 245 6.0E-8 T 28-03-2018 SMD44_RS35855 09682c4ca48227c8055aee5eee0d7d08 258 Gene3D G3DSA:3.90.320.10 3 205 4.7E-7 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMD44_RS35855 09682c4ca48227c8055aee5eee0d7d08 258 Pfam PF12705 PD-(D/E)XK nuclease superfamily 7 252 2.4E-25 T 28-03-2018 SMD44_RS17245 7b76422ec3c25b24a9ff29a7f2c81f8f 159 Gene3D G3DSA:3.40.630.30 3 156 1.2E-21 T 28-03-2018 SMD44_RS17245 7b76422ec3c25b24a9ff29a7f2c81f8f 159 Pfam PF00583 Acetyltransferase (GNAT) family 21 132 8.4E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS17245 7b76422ec3c25b24a9ff29a7f2c81f8f 159 SUPERFAMILY SSF55729 7 157 1.89E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS23070 d14c4bb37bfb124010a89bf3352b6fc7 115 Gene3D G3DSA:3.30.750.24 3 101 1.3E-10 T 28-03-2018 IPR002645 STAS domain SMD44_RS23070 d14c4bb37bfb124010a89bf3352b6fc7 115 SUPERFAMILY SSF52091 7 95 6.47E-15 T 28-03-2018 IPR002645 STAS domain SMD44_RS23070 d14c4bb37bfb124010a89bf3352b6fc7 115 Pfam PF13466 STAS domain 16 91 2.4E-9 T 28-03-2018 IPR002645 STAS domain SMD44_RS40330 b9871d483ed9a5c7c3a374faa731417e 218 Pfam PF01810 LysE type translocator 24 215 2.4E-13 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMD44_RS15250 4c3f138000e2ee81c8ba757e669b8350 354 Gene3D G3DSA:3.40.1030.10 79 354 4.2E-98 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS15250 4c3f138000e2ee81c8ba757e669b8350 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 13 74 1.3E-15 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS15250 4c3f138000e2ee81c8ba757e669b8350 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 13 345 34.797 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SMD44_RS15250 4c3f138000e2ee81c8ba757e669b8350 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 16 344 2.4E-109 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SMD44_RS15250 4c3f138000e2ee81c8ba757e669b8350 354 Gene3D G3DSA:1.20.970.10 9 75 4.6E-19 T 28-03-2018 SMD44_RS15250 4c3f138000e2ee81c8ba757e669b8350 354 Pfam PF00591 Glycosyl transferase family, a/b domain 82 335 1.4E-81 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS15250 4c3f138000e2ee81c8ba757e669b8350 354 SUPERFAMILY SSF47648 11 77 7.06E-18 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS15250 4c3f138000e2ee81c8ba757e669b8350 354 SUPERFAMILY SSF52418 81 348 6.41E-82 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD44_RS22600 7df713784ed8b21141e989b5dd7ae471 183 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 172 4.4E-37 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS22600 7df713784ed8b21141e989b5dd7ae471 183 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 183 25.187 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS22600 7df713784ed8b21141e989b5dd7ae471 183 Gene3D G3DSA:3.40.50.2020 1 183 3.0E-31 T 28-03-2018 SMD44_RS22600 7df713784ed8b21141e989b5dd7ae471 183 Pfam PF00156 Phosphoribosyl transferase domain 59 162 9.6E-13 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD44_RS22600 7df713784ed8b21141e989b5dd7ae471 183 SUPERFAMILY SSF53271 5 179 4.33E-38 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS30635 0a786757190e713ba1d38ac669ce64d7 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS30635 0a786757190e713ba1d38ac669ce64d7 454 Pfam PF00202 Aminotransferase class-III 30 446 1.4E-92 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS30635 0a786757190e713ba1d38ac669ce64d7 454 Gene3D G3DSA:3.90.1150.10 325 454 1.4E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS30635 0a786757190e713ba1d38ac669ce64d7 454 PIRSF PIRSF000521 29 406 1.9E-22 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS30635 0a786757190e713ba1d38ac669ce64d7 454 Gene3D G3DSA:3.40.640.10 75 324 1.5E-73 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS30635 0a786757190e713ba1d38ac669ce64d7 454 Gene3D G3DSA:3.90.1150.10 1 74 2.3E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS30635 0a786757190e713ba1d38ac669ce64d7 454 SUPERFAMILY SSF53383 10 449 6.69E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 Gene3D G3DSA:3.40.50.10490 1 148 1.1E-41 T 28-03-2018 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 Gene3D G3DSA:1.10.1390.10 515 553 2.3E-20 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 48 527 41.367 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 500 517 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 500 513 8.6E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 468 486 8.6E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 345 366 8.6E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 155 174 8.6E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 268 286 8.6E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 486 500 8.6E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 Gene3D G3DSA:3.40.50.10490 266 514 2.7E-117 T 28-03-2018 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 SUPERFAMILY SSF53697 9 551 7.41E-204 T 28-03-2018 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 Gene3D G3DSA:3.40.50.10490 149 265 9.1E-52 T 28-03-2018 SMD44_RS10095 064dc9e1cb8c446776fff31a0dbc6d3e 553 Pfam PF00342 Phosphoglucose isomerase 54 544 3.4E-216 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD44_RS06670 841c7e67086c5037fe4752028f0c97f7 149 Gene3D G3DSA:2.70.70.10 1 149 5.6E-50 T 28-03-2018 SMD44_RS06670 841c7e67086c5037fe4752028f0c97f7 149 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 3 125 5.5E-39 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SMD44_RS06670 841c7e67086c5037fe4752028f0c97f7 149 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 5 122 2.1E-29 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SMD44_RS06670 841c7e67086c5037fe4752028f0c97f7 149 SUPERFAMILY SSF51261 3 147 8.02E-38 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS10030 80600b94739a27ce4f7212fd5dd6c7ad 308 Gene3D G3DSA:3.40.50.300 3 235 9.5E-60 T 28-03-2018 SMD44_RS10030 80600b94739a27ce4f7212fd5dd6c7ad 308 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS10030 80600b94739a27ce4f7212fd5dd6c7ad 308 SMART SM00382 31 217 7.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS10030 80600b94739a27ce4f7212fd5dd6c7ad 308 SUPERFAMILY SSF52540 6 221 2.06E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10030 80600b94739a27ce4f7212fd5dd6c7ad 308 Pfam PF00005 ABC transporter 23 161 2.6E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 SUPERFAMILY SSF51735 159 396 1.78E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 PIRSF PIRSF000185 2 397 1.5E-94 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 161 317 5.6E-31 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 SUPERFAMILY SSF53223 4 123 1.7E-22 T 28-03-2018 SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 13 91 2.5E-11 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 Gene3D G3DSA:3.40.50.720 153 397 6.1E-41 T 28-03-2018 SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 SMART SM00839 153 394 1.9E-56 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 Gene3D G3DSA:3.40.50.10860 2 138 4.8E-28 T 28-03-2018 SMD44_RS35595 f86bc6c891eee94b4846e2a147a74fd7 402 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 63 76 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMD44_RS30905 5904e04d1e1e2b1b1f9c91d8e5663ac6 339 SUPERFAMILY SSF52540 20 263 6.83E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30905 5904e04d1e1e2b1b1f9c91d8e5663ac6 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 333 1.7E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS30905 5904e04d1e1e2b1b1f9c91d8e5663ac6 339 SMART SM00382 50 241 1.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS30905 5904e04d1e1e2b1b1f9c91d8e5663ac6 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 298 3.7E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS30905 5904e04d1e1e2b1b1f9c91d8e5663ac6 339 Gene3D G3DSA:3.40.50.300 16 324 6.6E-71 T 28-03-2018 SMD44_RS30905 5904e04d1e1e2b1b1f9c91d8e5663ac6 339 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS30905 5904e04d1e1e2b1b1f9c91d8e5663ac6 339 Pfam PF00005 ABC transporter 42 192 1.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19290 8b6550def7156d7e59424d12015ff8c8 84 Gene3D G3DSA:3.10.20.30 4 84 5.3E-16 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS19290 8b6550def7156d7e59424d12015ff8c8 84 SUPERFAMILY SSF54285 5 84 8.04E-12 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMD44_RS19290 8b6550def7156d7e59424d12015ff8c8 84 Pfam PF02597 ThiS family 7 84 4.3E-8 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMD44_RS04660 5058e26988af46ea3b58743d12c63c81 269 Gene3D G3DSA:1.10.260.40 78 104 1.0E-5 T 28-03-2018 SMD44_RS04660 5058e26988af46ea3b58743d12c63c81 269 Pfam PF13384 Homeodomain-like domain 230 264 4.1E-6 T 28-03-2018 SMD44_RS04660 5058e26988af46ea3b58743d12c63c81 269 SUPERFAMILY SSF46689 223 264 7.77E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS04660 5058e26988af46ea3b58743d12c63c81 269 Gene3D G3DSA:1.10.10.60 213 263 1.9E-9 T 28-03-2018 SMD44_RS04660 5058e26988af46ea3b58743d12c63c81 269 Gene3D G3DSA:1.10.260.40 119 176 0.012 T 28-03-2018 SMD44_RS04660 5058e26988af46ea3b58743d12c63c81 269 Gene3D G3DSA:1.10.10.60 46 77 3.5E-4 T 28-03-2018 SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 SUPERFAMILY SSF117892 54 187 1.16E-39 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 SMART SM00244 22 180 5.4E-62 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 Pfam PF01145 SPFH domain / Band 7 family 26 196 8.8E-34 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 PRINTS PR00721 Stomatin signature 175 196 3.9E-62 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 PRINTS PR00721 Stomatin signature 29 51 3.9E-62 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 PRINTS PR00721 Stomatin signature 112 129 3.9E-62 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 PRINTS PR00721 Stomatin signature 200 223 3.9E-62 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 PRINTS PR00721 Stomatin signature 77 98 3.9E-62 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 PRINTS PR00721 Stomatin signature 132 155 3.9E-62 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS05380 a3cb3bfd0fdaa2f75d997678a6424c2e 308 PRINTS PR00721 Stomatin signature 156 174 3.9E-62 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS19075 95314d0b9b89d6fa24163faeb37e00c1 448 Gene3D G3DSA:3.40.50.2000 239 416 1.0E-44 T 28-03-2018 SMD44_RS19075 95314d0b9b89d6fa24163faeb37e00c1 448 Pfam PF00534 Glycosyl transferases group 1 241 413 3.5E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS19075 95314d0b9b89d6fa24163faeb37e00c1 448 SUPERFAMILY SSF53756 30 434 3.77E-81 T 28-03-2018 SMD44_RS19075 95314d0b9b89d6fa24163faeb37e00c1 448 Pfam PF13439 Glycosyltransferase Family 4 49 230 2.7E-31 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS19075 95314d0b9b89d6fa24163faeb37e00c1 448 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 30 437 5.8E-199 T 28-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD44_RS19075 95314d0b9b89d6fa24163faeb37e00c1 448 Gene3D G3DSA:3.40.50.2000 43 238 1.1E-23 T 28-03-2018 SMD44_RS19075 95314d0b9b89d6fa24163faeb37e00c1 448 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 29 440 51.041 T 28-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD44_RS25325 d244b02e7fadac5b27e71052baec3a13 162 SUPERFAMILY SSF89963 5 87 3.4E-28 T 28-03-2018 IPR007551 Protein of unknown function DUF520 SMD44_RS25325 d244b02e7fadac5b27e71052baec3a13 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 25.267 T 28-03-2018 IPR007551 Protein of unknown function DUF520 SMD44_RS25325 d244b02e7fadac5b27e71052baec3a13 162 Gene3D G3DSA:3.30.70.990 12 96 1.1E-31 T 28-03-2018 IPR035570 UPF0234 N-terminal domain SMD44_RS25325 d244b02e7fadac5b27e71052baec3a13 162 SUPERFAMILY SSF89963 90 162 4.05E-24 T 28-03-2018 IPR007551 Protein of unknown function DUF520 SMD44_RS25325 d244b02e7fadac5b27e71052baec3a13 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 1.3E-60 T 28-03-2018 IPR007551 Protein of unknown function DUF520 SMD44_RS25325 d244b02e7fadac5b27e71052baec3a13 162 Gene3D G3DSA:3.30.70.860 97 162 1.8E-29 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain SMD44_RS16730 a157f1e5bb8024e05dc336cc8f4477f2 76 Pfam PF14117 Domain of unknown function (DUF4287) 9 67 3.5E-23 T 28-03-2018 IPR025629 Protein of unknown function DUF4287 SMD44_RS31895 0a1a64e6d2a55dfc0e6c204061349efa 227 SMART SM00862 149 225 1.3E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS31895 0a1a64e6d2a55dfc0e6c204061349efa 227 Pfam PF00072 Response regulator receiver domain 4 112 8.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31895 0a1a64e6d2a55dfc0e6c204061349efa 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 4.3E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS31895 0a1a64e6d2a55dfc0e6c204061349efa 227 SMART SM00448 2 112 6.8E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31895 0a1a64e6d2a55dfc0e6c204061349efa 227 Gene3D G3DSA:3.40.50.2300 1 121 1.6E-37 T 28-03-2018 SMD44_RS31895 0a1a64e6d2a55dfc0e6c204061349efa 227 SUPERFAMILY SSF52172 1 183 1.42E-40 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS31895 0a1a64e6d2a55dfc0e6c204061349efa 227 Gene3D G3DSA:1.10.10.10 122 227 5.4E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS42695 67c000aefaaca0270840f20b7acfe7d1 186 SUPERFAMILY SSF55811 44 174 7.58E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS42695 67c000aefaaca0270840f20b7acfe7d1 186 Gene3D G3DSA:3.90.79.10 34 184 1.3E-23 T 28-03-2018 SMD44_RS42695 67c000aefaaca0270840f20b7acfe7d1 186 Pfam PF00293 NUDIX domain 48 168 2.8E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS30725 22b32937bd841b6fe6defc544d480936 308 SUPERFAMILY SSF161098 23 301 1.7E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30725 22b32937bd841b6fe6defc544d480936 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 296 9.5E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30725 22b32937bd841b6fe6defc544d480936 308 Gene3D G3DSA:1.10.3720.10 27 302 2.8E-41 T 28-03-2018 SMD44_RS05770 5d5a2614f58c1ae9c2d372b5b08ecc1c 99 SUPERFAMILY SSF143120 5 55 4.97E-12 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMD44_RS05770 5d5a2614f58c1ae9c2d372b5b08ecc1c 99 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 56 3.7E-14 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMD44_RS05770 5d5a2614f58c1ae9c2d372b5b08ecc1c 99 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 53 1.1E-15 T 28-03-2018 SMD44_RS05770 5d5a2614f58c1ae9c2d372b5b08ecc1c 99 Gene3D G3DSA:3.40.1620.10 3 60 2.0E-16 T 28-03-2018 SMD44_RS12725 5869b02ae1df614f86432d4cb4df3e5a 403 Gene3D G3DSA:3.40.50.1820 169 383 6.9E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS12725 5869b02ae1df614f86432d4cb4df3e5a 403 Pfam PF06259 Alpha/beta hydrolase 158 331 3.9E-55 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 SMD44_RS12725 5869b02ae1df614f86432d4cb4df3e5a 403 SUPERFAMILY SSF53474 244 332 5.47E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS32360 86de45287e91f597dcb4246790974767 710 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 341 521 1.0E-56 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS32360 86de45287e91f597dcb4246790974767 710 Gene3D G3DSA:1.10.1040.10 524 609 2.5E-12 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS32360 86de45287e91f597dcb4246790974767 710 Gene3D G3DSA:1.10.1040.10 633 707 5.0E-6 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS32360 86de45287e91f597dcb4246790974767 710 Gene3D G3DSA:3.40.50.720 295 523 1.6E-52 T 28-03-2018 SMD44_RS32360 86de45287e91f597dcb4246790974767 710 Gene3D G3DSA:3.90.226.10 20 294 2.4E-32 T 28-03-2018 SMD44_RS32360 86de45287e91f597dcb4246790974767 710 SUPERFAMILY SSF48179 523 616 2.21E-17 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS32360 86de45287e91f597dcb4246790974767 710 Pfam PF00378 Enoyl-CoA hydratase/isomerase 54 236 2.0E-17 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS32360 86de45287e91f597dcb4246790974767 710 SUPERFAMILY SSF52096 35 221 3.89E-34 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS32360 86de45287e91f597dcb4246790974767 710 SUPERFAMILY SSF52096 254 328 3.89E-34 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS32360 86de45287e91f597dcb4246790974767 710 SUPERFAMILY SSF51735 339 523 9.26E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS32360 86de45287e91f597dcb4246790974767 710 SUPERFAMILY SSF48179 635 701 3.66E-10 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS32360 86de45287e91f597dcb4246790974767 710 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 525 607 4.6E-11 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 SUPERFAMILY SSF52172 3 128 8.25E-30 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 SMART SM00448 3 117 1.2E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 SMART SM00421 156 213 5.0E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 Pfam PF00072 Response regulator receiver domain 5 118 1.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 SUPERFAMILY SSF46894 149 218 6.46E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 213 3.8E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 Gene3D G3DSA:3.40.50.2300 2 135 1.3E-34 T 28-03-2018 SMD44_RS10630 e43e61b36c7093bfce0b2dbca0dd5dd7 223 Gene3D G3DSA:1.10.10.10 136 218 7.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16755 57c8a2e9685e03c0a66c0ece77b32e54 272 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS16755 57c8a2e9685e03c0a66c0ece77b32e54 272 SMART SM00382 59 245 6.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16755 57c8a2e9685e03c0a66c0ece77b32e54 272 Gene3D G3DSA:3.40.50.300 26 271 4.5E-62 T 28-03-2018 SMD44_RS16755 57c8a2e9685e03c0a66c0ece77b32e54 272 Pfam PF00005 ABC transporter 50 196 1.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS16755 57c8a2e9685e03c0a66c0ece77b32e54 272 SUPERFAMILY SSF52540 33 249 3.51E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30715 a809fef57434612120b13491a31f127b 414 Gene3D G3DSA:3.40.190.10 75 204 1.2E-16 T 28-03-2018 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 SUPERFAMILY SSF53850 74 409 3.26E-61 T 28-03-2018 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 311 330 3.1E-10 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 135 149 3.1E-10 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 267 286 3.1E-10 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 151 164 3.1E-10 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 228 247 3.1E-10 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 183 199 3.1E-10 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 Gene3D G3DSA:3.40.190.10 205 362 7.5E-29 T 28-03-2018 SMD44_RS30715 a809fef57434612120b13491a31f127b 414 Pfam PF13416 Bacterial extracellular solute-binding protein 98 375 8.5E-29 T 28-03-2018 SMD44_RS04075 0d8c7bc219156236b9fc90fc28d5b8df 233 SMART SM00342 144 220 2.7E-4 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS04075 0d8c7bc219156236b9fc90fc28d5b8df 233 Pfam PF12833 Helix-turn-helix domain 148 221 4.6E-11 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS04075 0d8c7bc219156236b9fc90fc28d5b8df 233 Gene3D G3DSA:1.10.10.60 145 178 0.057 T 28-03-2018 SMD44_RS04075 0d8c7bc219156236b9fc90fc28d5b8df 233 Gene3D G3DSA:1.10.10.60 179 223 6.5E-5 T 28-03-2018 SMD44_RS18645 d4d3d329bced6f1effbe7cdd028e700f 289 Gene3D G3DSA:2.40.10.10 187 289 8.9E-28 T 28-03-2018 SMD44_RS18645 d4d3d329bced6f1effbe7cdd028e700f 289 SUPERFAMILY SSF50494 79 266 7.15E-19 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS18645 d4d3d329bced6f1effbe7cdd028e700f 289 Gene3D G3DSA:2.40.10.10 72 186 2.7E-10 T 28-03-2018 SMD44_RS18645 d4d3d329bced6f1effbe7cdd028e700f 289 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 110 115 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS18645 d4d3d329bced6f1effbe7cdd028e700f 289 Pfam PF00089 Trypsin 90 219 4.3E-5 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS07175 69236b3aa1960d3adc57c50b59a5dddd 713 Gene3D G3DSA:1.20.1640.10 490 700 1.0E-26 T 28-03-2018 SMD44_RS07175 69236b3aa1960d3adc57c50b59a5dddd 713 SUPERFAMILY SSF82866 170 358 5.75E-32 T 28-03-2018 SMD44_RS07175 69236b3aa1960d3adc57c50b59a5dddd 713 Pfam PF03176 MMPL family 479 705 9.4E-50 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS07175 69236b3aa1960d3adc57c50b59a5dddd 713 Pfam PF03176 MMPL family 61 387 2.0E-70 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS07175 69236b3aa1960d3adc57c50b59a5dddd 713 SUPERFAMILY SSF82866 483 703 1.57E-24 T 28-03-2018 SMD44_RS07175 69236b3aa1960d3adc57c50b59a5dddd 713 Gene3D G3DSA:1.20.1640.10 144 355 7.5E-37 T 28-03-2018 SMD44_RS08600 8e6bcfe44449e4d5fcee7dc489ee8043 462 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS08600 8e6bcfe44449e4d5fcee7dc489ee8043 462 Gene3D G3DSA:3.40.309.10 261 446 2.2E-61 T 28-03-2018 SMD44_RS08600 8e6bcfe44449e4d5fcee7dc489ee8043 462 SUPERFAMILY SSF53720 4 460 8.12E-150 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS08600 8e6bcfe44449e4d5fcee7dc489ee8043 462 Pfam PF00171 Aldehyde dehydrogenase family 13 459 1.3E-155 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS08600 8e6bcfe44449e4d5fcee7dc489ee8043 462 Gene3D G3DSA:3.40.605.10 1 260 2.6E-87 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS27340 04a2c6f258227f85bd0c83af73d88669 236 SMART SM00858 41 103 0.0025 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SMD44_RS27340 04a2c6f258227f85bd0c83af73d88669 236 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 10 221 1.3E-28 T 28-03-2018 IPR017592 Pilus assembly, Flp-type CpaB SMD44_RS27340 04a2c6f258227f85bd0c83af73d88669 236 Pfam PF08666 SAF domain 46 102 2.5E-5 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SMD44_RS27340 04a2c6f258227f85bd0c83af73d88669 236 Gene3D G3DSA:3.90.1210.10 40 106 3.6E-9 T 28-03-2018 SMD44_RS27340 04a2c6f258227f85bd0c83af73d88669 236 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 107 214 1.6E-19 T 28-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain SMD44_RS04045 2fe5b93d293c9f07a72aa97935b34152 312 Gene3D G3DSA:3.20.20.140 6 32 1.5E-4 T 28-03-2018 SMD44_RS04045 2fe5b93d293c9f07a72aa97935b34152 312 Pfam PF02126 Phosphotriesterase family 17 302 4.5E-37 T 28-03-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 SMD44_RS04045 2fe5b93d293c9f07a72aa97935b34152 312 PIRSF PIRSF016839 6 311 8.1E-96 T 28-03-2018 SMD44_RS04045 2fe5b93d293c9f07a72aa97935b34152 312 SUPERFAMILY SSF51556 9 308 2.54E-64 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS04045 2fe5b93d293c9f07a72aa97935b34152 312 Gene3D G3DSA:3.20.20.140 33 307 7.2E-44 T 28-03-2018 SMD44_RS32605 299decde311e9fecf4f84172ebd51889 675 SUPERFAMILY SSF48452 155 220 2.98E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32605 299decde311e9fecf4f84172ebd51889 675 SUPERFAMILY SSF48452 3 86 1.48E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32605 299decde311e9fecf4f84172ebd51889 675 Gene3D G3DSA:1.25.40.10 44 95 1.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32605 299decde311e9fecf4f84172ebd51889 675 Gene3D G3DSA:1.25.40.10 1 43 1.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32605 299decde311e9fecf4f84172ebd51889 675 Gene3D G3DSA:1.25.40.10 136 522 2.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS32605 299decde311e9fecf4f84172ebd51889 675 Gene3D G3DSA:1.25.40.10 523 672 2.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 10 422 1.1E-77 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 SUPERFAMILY SSF103473 456 486 5.89E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 SUPERFAMILY SSF103473 243 414 5.89E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 SUPERFAMILY SSF103473 5 195 5.89E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 Gene3D G3DSA:1.20.1250.20 5 196 1.7E-38 T 28-03-2018 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 Gene3D G3DSA:1.20.1250.20 247 489 1.5E-34 T 28-03-2018 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 13 37 1.5E-9 T 28-03-2018 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 1.5E-9 T 28-03-2018 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 1.5E-9 T 28-03-2018 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 1.5E-9 T 28-03-2018 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 198 216 1.5E-9 T 28-03-2018 SMD44_RS22030 619b0c7b16d7adc9f3ed4dbac29da711 529 Pfam PF07690 Major Facilitator Superfamily 14 404 2.5E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS38585 a53ecc3aead648d31098c24cc5205be7 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 92 5.3E-11 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS38585 a53ecc3aead648d31098c24cc5205be7 107 SUPERFAMILY SSF54292 3 105 7.35E-29 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD44_RS38585 a53ecc3aead648d31098c24cc5205be7 107 PRINTS PR00355 Adrenodoxin signature 40 50 1.2E-7 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 SMD44_RS38585 a53ecc3aead648d31098c24cc5205be7 107 PRINTS PR00355 Adrenodoxin signature 59 73 1.2E-7 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 SMD44_RS38585 a53ecc3aead648d31098c24cc5205be7 107 PRINTS PR00355 Adrenodoxin signature 83 91 1.2E-7 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 SMD44_RS38585 a53ecc3aead648d31098c24cc5205be7 107 Gene3D G3DSA:3.10.20.30 2 106 1.9E-23 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS20610 6c4e64bb6a9fede5b12904f2b8aeab00 328 Gene3D G3DSA:3.10.450.50 1 51 7.1E-8 T 28-03-2018 SMD44_RS20610 6c4e64bb6a9fede5b12904f2b8aeab00 328 Pfam PF02810 SEC-C motif 33 49 5.8E-8 T 28-03-2018 IPR004027 SEC-C motif SMD44_RS20610 6c4e64bb6a9fede5b12904f2b8aeab00 328 SUPERFAMILY SSF103642 30 49 9.48E-7 T 28-03-2018 SMD44_RS25145 c206286620f36dc78d0e78a1cc802ec9 317 Gene3D G3DSA:3.40.50.300 10 266 5.6E-59 T 28-03-2018 SMD44_RS25145 c206286620f36dc78d0e78a1cc802ec9 317 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS25145 c206286620f36dc78d0e78a1cc802ec9 317 SMART SM00382 37 221 9.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS25145 c206286620f36dc78d0e78a1cc802ec9 317 Pfam PF00005 ABC transporter 29 173 2.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS25145 c206286620f36dc78d0e78a1cc802ec9 317 SUPERFAMILY SSF52540 11 233 1.25E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 Gene3D G3DSA:2.60.120.280 14 157 2.7E-13 T 28-03-2018 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 SUPERFAMILY SSF51215 6 160 5.62E-22 T 28-03-2018 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 Pfam PF02311 AraC-like ligand binding domain 28 143 4.3E-9 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 235 250 8.6E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 266 8.6E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 SUPERFAMILY SSF46689 219 269 3.32E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 Gene3D G3DSA:1.10.10.60 158 223 4.3E-8 T 28-03-2018 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 Pfam PF12833 Helix-turn-helix domain 190 267 1.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 Gene3D G3DSA:1.10.10.60 224 273 1.2E-14 T 28-03-2018 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 220 262 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS10600 1249d69aa3e16ca7f243044e6c49a89b 318 SMART SM00342 183 266 1.0E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS19595 f908b31e8f9dccc692614db96b2de82f 303 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 34 269 29.231 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMD44_RS19595 f908b31e8f9dccc692614db96b2de82f 303 Gene3D G3DSA:3.40.50.150 40 277 4.7E-33 T 28-03-2018 SMD44_RS19595 f908b31e8f9dccc692614db96b2de82f 303 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 92 268 1.8E-48 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMD44_RS19595 f908b31e8f9dccc692614db96b2de82f 303 Pfam PF02390 Putative methyltransferase 95 263 9.4E-53 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMD44_RS19595 f908b31e8f9dccc692614db96b2de82f 303 SUPERFAMILY SSF53335 27 268 2.15E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 SUPERFAMILY SSF48264 13 396 1.83E-86 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 Pfam PF00067 Cytochrome P450 31 370 2.0E-30 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 288 315 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 190 212 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 346 357 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 337 346 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 316 331 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 77 88 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 123 139 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 140 155 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 PRINTS PR00359 B-class P450 signature 271 282 3.2E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07145 8e049ed85c478a8a55f727ec3eb388d3 397 Gene3D G3DSA:1.10.630.10 15 397 5.9E-68 T 28-03-2018 SMD44_RS37895 86696183d116352eff398af002bd2ad5 186 Gene3D G3DSA:1.20.120.520 3 165 4.1E-25 T 28-03-2018 SMD44_RS37895 86696183d116352eff398af002bd2ad5 186 Pfam PF01814 Hemerythrin HHE cation binding domain 8 125 4.6E-14 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 SMD44_RS08470 d24589386899dc27a5d0249e0c6f5335 499 PIRSF PIRSF006060 1 489 2.0E-53 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS08470 d24589386899dc27a5d0249e0c6f5335 499 Pfam PF13520 Amino acid permease 22 432 6.6E-22 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS28435 e4dc2c2c2ed6622efddf2f2eaaae97d4 303 Gene3D G3DSA:3.40.50.1100 145 301 1.7E-13 T 28-03-2018 SMD44_RS28435 e4dc2c2c2ed6622efddf2f2eaaae97d4 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 14 299 1.2E-21 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS28435 e4dc2c2c2ed6622efddf2f2eaaae97d4 303 SUPERFAMILY SSF53686 14 299 2.16E-52 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS28435 e4dc2c2c2ed6622efddf2f2eaaae97d4 303 Gene3D G3DSA:3.40.50.1100 48 144 1.7E-29 T 28-03-2018 SMD44_RS28435 e4dc2c2c2ed6622efddf2f2eaaae97d4 303 PIRSF PIRSF006278 1 303 1.5E-83 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase SMD44_RS25670 7673b8629578b07a1b91f6b9c45b44a4 174 Gene3D G3DSA:3.30.230.10 43 174 1.9E-46 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS25670 7673b8629578b07a1b91f6b9c45b44a4 174 ProSitePatterns PS00360 Ribosomal protein S9 signature. 112 130 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 SMD44_RS25670 7673b8629578b07a1b91f6b9c45b44a4 174 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 44 174 32.555 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid SMD44_RS25670 7673b8629578b07a1b91f6b9c45b44a4 174 SUPERFAMILY SSF54211 50 174 1.74E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS25670 7673b8629578b07a1b91f6b9c45b44a4 174 Pfam PF00380 Ribosomal protein S9/S16 53 174 7.6E-43 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 SMD44_RS19475 cd7cd4b9946414761fbb3d1660723cda 281 Gene3D G3DSA:3.10.450.50 108 247 0.0018 T 28-03-2018 SMD44_RS35815 4ab03eeff44b8e21b94dc1e9c83521ef 470 Pfam PF03354 Phage Terminase 64 314 5.3E-8 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type SMD44_RS00345 1bcdf3b342385b497262d8276b2b4cff 260 Pfam PF00248 Aldo/keto reductase family 30 225 7.7E-37 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS00345 1bcdf3b342385b497262d8276b2b4cff 260 SUPERFAMILY SSF51430 1 227 1.7E-53 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS00345 1bcdf3b342385b497262d8276b2b4cff 260 Gene3D G3DSA:3.20.20.100 32 234 1.0E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS00345 1bcdf3b342385b497262d8276b2b4cff 260 Gene3D G3DSA:3.20.20.100 1 31 4.4E-4 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS20920 d4c6ba522082833645071690981a2fbd 292 SUPERFAMILY SSF55729 11 269 3.95E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS20920 d4c6ba522082833645071690981a2fbd 292 Gene3D G3DSA:3.40.630.30 1 145 1.4E-16 T 28-03-2018 SMD44_RS20920 d4c6ba522082833645071690981a2fbd 292 Pfam PF13673 Acetyltransferase (GNAT) domain 77 137 2.3E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS20920 d4c6ba522082833645071690981a2fbd 292 Gene3D G3DSA:3.40.630.30 146 271 9.4E-9 T 28-03-2018 SMD44_RS05995 954b871ed80f2dbe5ee5e165b958bef2 345 Gene3D G3DSA:3.40.50.300 52 262 1.7E-38 T 28-03-2018 SMD44_RS05995 954b871ed80f2dbe5ee5e165b958bef2 345 Gene3D G3DSA:1.10.287.130 264 325 4.1E-25 T 28-03-2018 SMD44_RS05995 954b871ed80f2dbe5ee5e165b958bef2 345 SUPERFAMILY SSF52540 5 325 6.09E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS05995 954b871ed80f2dbe5ee5e165b958bef2 345 Pfam PF03308 ArgK protein 22 293 1.6E-112 T 28-03-2018 SMD44_RS05995 954b871ed80f2dbe5ee5e165b958bef2 345 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 322 1.1E-115 T 28-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD44_RS05995 954b871ed80f2dbe5ee5e165b958bef2 345 Gene3D G3DSA:1.20.5.170 6 50 4.1E-21 T 28-03-2018 SMD44_RS02270 9505e94939c99aac6e5d966aafae1b10 252 SUPERFAMILY SSF53474 10 245 6.99E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02270 9505e94939c99aac6e5d966aafae1b10 252 Pfam PF00975 Thioesterase domain 23 241 7.5E-61 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS02270 9505e94939c99aac6e5d966aafae1b10 252 SMART SM00824 Thioesterase 25 245 1.5E-5 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD44_RS02270 9505e94939c99aac6e5d966aafae1b10 252 Gene3D G3DSA:3.40.50.1820 3 248 3.0E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS00385 aedbf04aeeba4cfae3d47dd98eaeecad 323 Gene3D G3DSA:3.40.50.720 146 241 5.5E-22 T 28-03-2018 SMD44_RS00385 aedbf04aeeba4cfae3d47dd98eaeecad 323 SUPERFAMILY SSF51735 109 277 4.17E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS00385 aedbf04aeeba4cfae3d47dd98eaeecad 323 Gene3D G3DSA:3.90.180.10 1 145 3.0E-47 T 28-03-2018 SMD44_RS00385 aedbf04aeeba4cfae3d47dd98eaeecad 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 85 4.2E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS00385 aedbf04aeeba4cfae3d47dd98eaeecad 323 SMART SM00829 10 321 7.6E-38 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS00385 aedbf04aeeba4cfae3d47dd98eaeecad 323 SUPERFAMILY SSF50129 1 142 3.93E-41 T 28-03-2018 IPR011032 GroES-like SMD44_RS00385 aedbf04aeeba4cfae3d47dd98eaeecad 323 Gene3D G3DSA:3.90.180.10 242 323 0.018 T 28-03-2018 SMD44_RS00385 aedbf04aeeba4cfae3d47dd98eaeecad 323 Pfam PF00107 Zinc-binding dehydrogenase 149 253 1.5E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS05645 ec80b78b0ab6c40eb32d0e3556176aa4 62 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 8 56 8.1E-9 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD44_RS05645 ec80b78b0ab6c40eb32d0e3556176aa4 62 Pfam PF12728 Helix-turn-helix domain 8 57 2.1E-12 T 28-03-2018 SMD44_RS05645 ec80b78b0ab6c40eb32d0e3556176aa4 62 Gene3D G3DSA:1.10.10.10 8 61 1.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 ProSitePatterns PS00449 ATP synthase a subunit signature. 180 189 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 18 251 3.4E-38 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 PRINTS PR00123 ATP synthase A subunit signature 235 250 3.5E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 PRINTS PR00123 ATP synthase A subunit signature 177 199 3.5E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 PRINTS PR00123 ATP synthase A subunit signature 92 108 3.5E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 Gene3D G3DSA:1.20.120.220 79 255 1.3E-31 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 SUPERFAMILY SSF81336 84 249 8.37E-32 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 Pfam PF00119 ATP synthase A chain 34 249 3.0E-48 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28865 2f8cda2d4fba8d6c197740bfa86288a3 256 Hamap MF_01393 ATP synthase subunit a [atpB]. 21 255 12.324 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 Hamap MF_00152 Probable endonuclease 4 [nfo]. 18 297 38.8 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 Pfam PF01261 Xylose isomerase-like TIM barrel 35 256 4.1E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 232 248 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 20 294 2.4E-60 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 192 199 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 Gene3D G3DSA:3.20.20.150 17 299 1.5E-47 T 28-03-2018 SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 83 91 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 SUPERFAMILY SSF51658 20 297 5.76E-72 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS11180 451bcc172fe087600186835c17bd82f9 299 SMART SM00518 19 297 1.1E-111 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMD44_RS36365 4344b3392e4ef906282fd528b16d9c14 436 SUPERFAMILY SSF102114 159 415 2.16E-10 T 28-03-2018 SMD44_RS36365 4344b3392e4ef906282fd528b16d9c14 436 Gene3D G3DSA:3.20.20.70 131 423 8.8E-14 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 Pfam PF01479 S4 domain 7 49 1.2E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 PIRSF PIRSF005578 3 268 7.3E-93 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 Gene3D G3DSA:3.40.50.150 68 268 1.4E-54 T 28-03-2018 SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 SUPERFAMILY SSF55174 6 67 1.09E-10 T 28-03-2018 SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 8 245 4.8E-59 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 Gene3D G3DSA:3.10.290.10 3 67 9.6E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 SUPERFAMILY SSF53335 57 251 2.82E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 Pfam PF01728 FtsJ-like methyltransferase 65 250 8.6E-18 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 SMD44_RS09170 2fdf99a13b9808a06890815ef4a4d121 271 SMART SM00363 7 74 1.0E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS38990 2f4da880d897bc85c8b423017bdbe379 157 Gene3D G3DSA:3.10.129.10 30 155 7.9E-26 T 28-03-2018 SMD44_RS38990 2f4da880d897bc85c8b423017bdbe379 157 SUPERFAMILY SSF54637 32 151 4.48E-22 T 28-03-2018 IPR029069 HotDog domain SMD44_RS38990 2f4da880d897bc85c8b423017bdbe379 157 Pfam PF13279 Thioesterase-like superfamily 43 144 1.7E-10 T 28-03-2018 SMD44_RS01360 6a03c07949d75892f9ab0db9a492dd07 549 SUPERFAMILY SSF56601 220 516 3.48E-73 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS01360 6a03c07949d75892f9ab0db9a492dd07 549 Gene3D G3DSA:3.40.710.10 192 536 5.1E-74 T 28-03-2018 SMD44_RS01360 6a03c07949d75892f9ab0db9a492dd07 549 Pfam PF00144 Beta-lactamase 198 508 8.3E-61 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS02685 a4f20cc5fc804a58152410d0ddcc511c 292 Gene3D G3DSA:1.10.260.40 24 99 0.0056 T 28-03-2018 SMD44_RS02685 a4f20cc5fc804a58152410d0ddcc511c 292 Gene3D G3DSA:1.10.10.10 176 292 4.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02685 a4f20cc5fc804a58152410d0ddcc511c 292 SUPERFAMILY SSF88659 230 288 3.49E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21540 ae85c16972c7b7f1c299a2a91f4f03d4 343 SUPERFAMILY SSF55729 80 246 2.77E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS21540 ae85c16972c7b7f1c299a2a91f4f03d4 343 Gene3D G3DSA:3.40.630.30 54 247 1.0E-20 T 28-03-2018 SMD44_RS25410 aa2fbfca40d734f1dd93447a162bc2c3 95 Gene3D G3DSA:1.20.5.1030 39 90 1.6E-20 T 28-03-2018 SMD44_RS25410 aa2fbfca40d734f1dd93447a162bc2c3 95 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 42 70 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS25410 aa2fbfca40d734f1dd93447a162bc2c3 95 Hamap MF_00422 Protein translocase subunit SecE [secE]. 37 92 13.648 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS25410 aa2fbfca40d734f1dd93447a162bc2c3 95 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 42 93 8.4E-20 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD44_RS25410 aa2fbfca40d734f1dd93447a162bc2c3 95 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 41 95 5.0E-23 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SMD44_RS25160 293722df7acd22f6a06a9ffedd7b8f71 320 Pfam PF04389 Peptidase family M28 109 314 1.4E-49 T 28-03-2018 IPR007484 Peptidase M28 SMD44_RS25160 293722df7acd22f6a06a9ffedd7b8f71 320 Gene3D G3DSA:3.40.630.10 44 320 3.0E-65 T 28-03-2018 SMD44_RS25160 293722df7acd22f6a06a9ffedd7b8f71 320 SUPERFAMILY SSF53187 54 318 4.1E-68 T 28-03-2018 SMD44_RS17305 8b6ef3e6cfeb559a22cb702e1645fc62 300 SUPERFAMILY SSF53448 8 287 2.38E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS17305 8b6ef3e6cfeb559a22cb702e1645fc62 300 Gene3D G3DSA:3.90.550.10 1 300 2.0E-60 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS17305 8b6ef3e6cfeb559a22cb702e1645fc62 300 Pfam PF00483 Nucleotidyl transferase 10 273 1.9E-27 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD44_RS17305 8b6ef3e6cfeb559a22cb702e1645fc62 300 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 8.7E-104 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 SMD44_RS24670 19ed8bd647759b2f72222de8d043b16a 283 Gene3D G3DSA:3.40.50.300 2 255 3.5E-9 T 28-03-2018 SMD44_RS24670 19ed8bd647759b2f72222de8d043b16a 283 SUPERFAMILY SSF52540 3 229 2.05E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS40655 301484addaeccdac307c409bf583f95a 158 Gene3D G3DSA:1.10.10.10 34 92 1.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40655 301484addaeccdac307c409bf583f95a 158 Gene3D G3DSA:1.10.10.10 93 149 2.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40655 301484addaeccdac307c409bf583f95a 158 SUPERFAMILY SSF48452 34 131 9.11E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40655 301484addaeccdac307c409bf583f95a 158 Pfam PF13424 Tetratricopeptide repeat 64 127 2.3E-14 T 28-03-2018 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 PIRSF PIRSF016578 128 384 9.4E-9 T 28-03-2018 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 PIRSF PIRSF016578 3 114 6.3E-4 T 28-03-2018 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 222 6.4E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 SUPERFAMILY SSF56645 2 247 1.7E-79 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 1.3E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 Gene3D G3DSA:1.20.140.10 223 384 3.9E-55 T 28-03-2018 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.1E-37 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 Gene3D G3DSA:2.40.110.10 121 222 1.1E-31 T 28-03-2018 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 Gene3D G3DSA:1.10.540.10 1 120 7.2E-40 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS14965 ae26ed162dd816470dea1b2844ed1808 386 SUPERFAMILY SSF47203 232 382 1.05E-51 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS10295 949a079fa20526383e38679792ad1ccc 139 Pfam PF00571 CBS domain 81 123 1.5E-8 T 28-03-2018 IPR000644 CBS domain SMD44_RS10295 949a079fa20526383e38679792ad1ccc 139 Pfam PF00571 CBS domain 4 55 2.9E-9 T 28-03-2018 IPR000644 CBS domain SMD44_RS10295 949a079fa20526383e38679792ad1ccc 139 SUPERFAMILY SSF54631 2 127 4.42E-31 T 28-03-2018 SMD44_RS10295 949a079fa20526383e38679792ad1ccc 139 Gene3D G3DSA:3.10.580.10 1 134 2.8E-27 T 28-03-2018 SMD44_RS10295 949a079fa20526383e38679792ad1ccc 139 SMART SM00116 77 124 1.9E-4 T 28-03-2018 IPR000644 CBS domain SMD44_RS10295 949a079fa20526383e38679792ad1ccc 139 SMART SM00116 11 59 0.0024 T 28-03-2018 IPR000644 CBS domain SMD44_RS20635 3171d570b444217829ecea79b1146407 424 Pfam PF07690 Major Facilitator Superfamily 16 359 1.3E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS20635 3171d570b444217829ecea79b1146407 424 Gene3D G3DSA:1.20.1250.20 7 191 9.7E-17 T 28-03-2018 SMD44_RS20635 3171d570b444217829ecea79b1146407 424 SUPERFAMILY SSF103473 14 386 6.54E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20635 3171d570b444217829ecea79b1146407 424 Gene3D G3DSA:1.20.1250.20 201 395 1.8E-8 T 28-03-2018 SMD44_RS12760 015a5d999749e70f308422dcc0f37ed3 379 Gene3D G3DSA:1.20.1420.10 1 295 5.7E-4 T 28-03-2018 SMD44_RS12760 015a5d999749e70f308422dcc0f37ed3 379 Gene3D G3DSA:1.10.10.60 296 347 1.3E-4 T 28-03-2018 SMD44_RS12760 015a5d999749e70f308422dcc0f37ed3 379 Pfam PF13556 PucR C-terminal helix-turn-helix domain 311 368 6.5E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS11270 4be598c64d63b8d893003e9d6132c76b 390 SUPERFAMILY SSF49764 306 380 2.62E-5 T 28-03-2018 IPR008978 HSP20-like chaperone SMD44_RS11270 4be598c64d63b8d893003e9d6132c76b 390 Pfam PF02374 Anion-transporting ATPase 1 278 4.7E-30 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMD44_RS11270 4be598c64d63b8d893003e9d6132c76b 390 Gene3D G3DSA:3.40.50.300 2 302 2.4E-46 T 28-03-2018 SMD44_RS11270 4be598c64d63b8d893003e9d6132c76b 390 SUPERFAMILY SSF52540 1 273 1.33E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 Gene3D G3DSA:3.30.420.40 147 296 1.2E-16 T 28-03-2018 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 339 57.711 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 313 1.0E-91 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 Pfam PF00814 Glycoprotease family 27 313 2.5E-90 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 Gene3D G3DSA:3.30.420.40 5 146 7.3E-38 T 28-03-2018 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 318 2.1E-116 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 159 180 1.5E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 1.5E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 1.5E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 270 279 1.5E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 1.5E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 1.5E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD44_RS39960 a06e4a48b72a2350aefa545aa37d267e 354 SUPERFAMILY SSF53067 5 315 5.55E-37 T 28-03-2018 SMD44_RS06150 55e630ed1ea16449bb02d04be3d15310 332 Pfam PF01435 Peptidase family M48 163 210 1.1E-7 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD44_RS06150 55e630ed1ea16449bb02d04be3d15310 332 Gene3D G3DSA:3.30.2010.10 99 208 1.5E-16 T 28-03-2018 SMD44_RS32785 e7619eac66532b39b9b58a6d9ed53fda 309 SMART SM00460 90 153 2.9E-4 T 28-03-2018 IPR002931 Transglutaminase-like SMD44_RS32785 e7619eac66532b39b9b58a6d9ed53fda 309 SUPERFAMILY SSF54001 94 188 5.05E-16 T 28-03-2018 SMD44_RS32785 e7619eac66532b39b9b58a6d9ed53fda 309 Pfam PF01841 Transglutaminase-like superfamily 95 151 1.4E-11 T 28-03-2018 IPR002931 Transglutaminase-like SMD44_RS27960 a052519d9f813cbb959d53493ca39cd7 265 SUPERFAMILY SSF47240 55 174 3.79E-9 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS27960 a052519d9f813cbb959d53493ca39cd7 265 Gene3D G3DSA:1.20.1260.10 48 265 3.2E-46 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS27960 a052519d9f813cbb959d53493ca39cd7 265 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 49 233 1.4E-95 T 28-03-2018 SMD44_RS19560 cee76a012d7c1f3d0a9907e1fa52d4fc 452 Gene3D G3DSA:3.50.50.60 6 166 4.2E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19560 cee76a012d7c1f3d0a9907e1fa52d4fc 452 Gene3D G3DSA:3.40.50.720 173 403 2.0E-29 T 28-03-2018 SMD44_RS19560 cee76a012d7c1f3d0a9907e1fa52d4fc 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 342 2.5E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19560 cee76a012d7c1f3d0a9907e1fa52d4fc 452 SUPERFAMILY SSF51905 2 232 7.98E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19560 cee76a012d7c1f3d0a9907e1fa52d4fc 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 2.1E-9 T 28-03-2018 SMD44_RS19560 cee76a012d7c1f3d0a9907e1fa52d4fc 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.1E-9 T 28-03-2018 SMD44_RS19560 cee76a012d7c1f3d0a9907e1fa52d4fc 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.1E-9 T 28-03-2018 SMD44_RS19560 cee76a012d7c1f3d0a9907e1fa52d4fc 452 SUPERFAMILY SSF51905 172 355 4.74E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS05320 63ec16e1164fc7622e9f73ac9ebd4a60 472 SUPERFAMILY SSF52540 32 272 4.66E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS05320 63ec16e1164fc7622e9f73ac9ebd4a60 472 Pfam PF00005 ABC transporter 51 190 6.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS05320 63ec16e1164fc7622e9f73ac9ebd4a60 472 Gene3D G3DSA:3.40.50.300 29 343 7.1E-60 T 28-03-2018 SMD44_RS05320 63ec16e1164fc7622e9f73ac9ebd4a60 472 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS05320 63ec16e1164fc7622e9f73ac9ebd4a60 472 SMART SM00382 60 242 6.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS05320 63ec16e1164fc7622e9f73ac9ebd4a60 472 Pfam PF09821 C-terminal AAA-associated domain 331 447 1.9E-35 T 28-03-2018 IPR018632 C-terminal AAA-associated domain SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 SUPERFAMILY SSF51735 261 314 2.21E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 SUPERFAMILY SSF51735 419 476 2.21E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 SUPERFAMILY SSF51735 35 179 2.26E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 Pfam PF01658 Myo-inositol-1-phosphate synthase 316 420 6.3E-24 T 28-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 SUPERFAMILY SSF55347 315 419 6.28E-28 T 28-03-2018 SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 Gene3D G3DSA:3.30.360.10 328 401 8.5E-25 T 28-03-2018 SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 PIRSF PIRSF015578 237 481 4.2E-65 T 28-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 PIRSF PIRSF015578 28 193 1.7E-20 T 28-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 Gene3D G3DSA:3.40.50.720 402 474 0.042 T 28-03-2018 SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 Gene3D G3DSA:3.40.50.720 24 327 1.9E-94 T 28-03-2018 SMD44_RS34745 8e97d64dede0a4a57ae4330d64773ef7 482 Pfam PF07994 Myo-inositol-1-phosphate synthase 264 456 2.8E-17 T 28-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 SUPERFAMILY SSF56655 10 262 2.75E-40 T 28-03-2018 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 Gene3D G3DSA:3.40.190.80 160 263 4.3E-13 T 28-03-2018 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 Gene3D G3DSA:3.30.540.10 7 134 1.5E-21 T 28-03-2018 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 Pfam PF00459 Inositol monophosphatase family 13 258 1.9E-30 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 3.4E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 3.4E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 3.4E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 3.4E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS40775 91d9eaee2d236e745c86c2a819a67467 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 3.4E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMD44_RS28880 7c872cae85614045df6791505c92cb1a 274 Pfam PF00213 ATP synthase delta (OSCP) subunit 110 269 8.5E-34 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28880 7c872cae85614045df6791505c92cb1a 274 PRINTS PR00125 ATP synthase delta subunit signature 231 246 5.9E-7 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28880 7c872cae85614045df6791505c92cb1a 274 PRINTS PR00125 ATP synthase delta subunit signature 246 264 5.9E-7 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28880 7c872cae85614045df6791505c92cb1a 274 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 112 266 2.1E-20 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28880 7c872cae85614045df6791505c92cb1a 274 Hamap MF_01416 ATP synthase subunit delta [atpD]. 97 273 14.73 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28880 7c872cae85614045df6791505c92cb1a 274 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 233 252 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28880 7c872cae85614045df6791505c92cb1a 274 Gene3D G3DSA:1.10.520.20 110 202 1.0E-15 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28880 7c872cae85614045df6791505c92cb1a 274 Gene3D G3DSA:1.10.520.20 10 109 1.4E-10 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS12045 0ae7f2d57655c4a3e35b46f9c7402c93 521 Pfam PF04213 Htaa 43 208 3.5E-54 T 28-03-2018 IPR007331 Htaa SMD44_RS12045 0ae7f2d57655c4a3e35b46f9c7402c93 521 Pfam PF04213 Htaa 257 409 2.9E-43 T 28-03-2018 IPR007331 Htaa SMD44_RS07965 3a8c526b6fe63ed3e80d2ca9b529cca9 433 Pfam PF12710 haloacid dehalogenase-like hydrolase 185 349 1.2E-10 T 28-03-2018 SMD44_RS07965 3a8c526b6fe63ed3e80d2ca9b529cca9 433 Gene3D G3DSA:3.40.50.1000 74 364 1.1E-11 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS07965 3a8c526b6fe63ed3e80d2ca9b529cca9 433 SUPERFAMILY SSF56784 76 89 8.6E-15 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS07965 3a8c526b6fe63ed3e80d2ca9b529cca9 433 SUPERFAMILY SSF56784 125 352 8.6E-15 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS15865 48336c2f1285d311cf052e57ba602495 232 SUPERFAMILY SSF141523 80 201 2.22E-18 T 28-03-2018 SMD44_RS15865 48336c2f1285d311cf052e57ba602495 232 Gene3D G3DSA:2.40.440.10 75 203 2.3E-20 T 28-03-2018 SMD44_RS15865 48336c2f1285d311cf052e57ba602495 232 Pfam PF03734 L,D-transpeptidase catalytic domain 83 201 5.1E-13 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD44_RS18760 e0bc5fa34fd318662ceb71eb62971ce1 309 Pfam PF01380 SIS domain 146 275 1.2E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS18760 e0bc5fa34fd318662ceb71eb62971ce1 309 Pfam PF01418 Helix-turn-helix domain, rpiR family 20 93 1.8E-12 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMD44_RS18760 e0bc5fa34fd318662ceb71eb62971ce1 309 SUPERFAMILY SSF46689 21 92 5.38E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS18760 e0bc5fa34fd318662ceb71eb62971ce1 309 Gene3D G3DSA:3.40.50.10490 115 301 6.0E-34 T 28-03-2018 SMD44_RS18760 e0bc5fa34fd318662ceb71eb62971ce1 309 Gene3D G3DSA:1.10.10.10 18 114 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18760 e0bc5fa34fd318662ceb71eb62971ce1 309 SUPERFAMILY SSF53697 115 281 3.77E-35 T 28-03-2018 SMD44_RS34400 9811782b9f5fb8520af2a8823516060f 542 Pfam PF00005 ABC transporter 21 191 1.3E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS34400 9811782b9f5fb8520af2a8823516060f 542 Pfam PF00005 ABC transporter 348 478 5.3E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS34400 9811782b9f5fb8520af2a8823516060f 542 Gene3D G3DSA:3.40.50.300 330 542 1.9E-31 T 28-03-2018 SMD44_RS34400 9811782b9f5fb8520af2a8823516060f 542 SUPERFAMILY SSF52540 347 527 2.33E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34400 9811782b9f5fb8520af2a8823516060f 542 SMART SM00382 29 236 1.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS34400 9811782b9f5fb8520af2a8823516060f 542 SMART SM00382 356 530 2.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS34400 9811782b9f5fb8520af2a8823516060f 542 SUPERFAMILY SSF52540 15 233 5.5E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34400 9811782b9f5fb8520af2a8823516060f 542 Gene3D G3DSA:3.40.50.300 3 329 3.4E-41 T 28-03-2018 SMD44_RS30325 1c8c4deab5ba15a1a7b3baaa191a7b13 578 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 578 6.3E-135 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV SMD44_RS30325 1c8c4deab5ba15a1a7b3baaa191a7b13 578 SMART SM01121 273 578 2.3E-98 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain SMD44_RS30325 1c8c4deab5ba15a1a7b3baaa191a7b13 578 Pfam PF13684 Dihydroxyacetone kinase family 275 578 1.7E-78 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain SMD44_RS30325 1c8c4deab5ba15a1a7b3baaa191a7b13 578 SUPERFAMILY SSF101473 6 108 1.44E-27 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS30325 1c8c4deab5ba15a1a7b3baaa191a7b13 578 SUPERFAMILY SSF101473 143 237 1.44E-27 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS30325 1c8c4deab5ba15a1a7b3baaa191a7b13 578 SMART SM01120 35 235 2.4E-39 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS30325 1c8c4deab5ba15a1a7b3baaa191a7b13 578 Pfam PF02734 DAK2 domain 35 233 2.5E-26 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD44_RS05420 b13cbfac58b65bb6a223033f60977600 300 Gene3D G3DSA:1.10.1040.10 175 300 1.1E-12 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS05420 b13cbfac58b65bb6a223033f60977600 300 SUPERFAMILY SSF51735 19 173 1.32E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS05420 b13cbfac58b65bb6a223033f60977600 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 20 172 1.8E-24 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS05420 b13cbfac58b65bb6a223033f60977600 300 PIRSF PIRSF000103 12 300 6.7E-44 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS05420 b13cbfac58b65bb6a223033f60977600 300 Gene3D G3DSA:3.40.50.720 3 174 1.1E-32 T 28-03-2018 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 Gene3D G3DSA:1.10.390.10 292 458 7.4E-46 T 28-03-2018 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 142 157 2.4E-18 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 306 321 2.4E-18 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 2.4E-18 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 325 337 2.4E-18 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 272 282 2.4E-18 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 855 0.0 T 28-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 SUPERFAMILY SSF55486 220 464 1.95E-73 T 28-03-2018 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 Gene3D G3DSA:2.60.40.1730 16 202 6.2E-30 T 28-03-2018 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 Pfam PF01433 Peptidase family M1 domain 243 454 4.3E-58 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 SUPERFAMILY SSF63737 10 201 4.58E-33 T 28-03-2018 SMD44_RS14260 b8089339689b9b9354ed36fa19a55d1c 862 Pfam PF11838 ERAP1-like C-terminal domain 537 848 7.1E-63 T 28-03-2018 IPR024571 ERAP1-like C-terminal domain SMD44_RS16010 cbd25011fb8b4575fd4a8866b4e68797 717 SUPERFAMILY SSF53448 356 594 1.13E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16010 cbd25011fb8b4575fd4a8866b4e68797 717 Gene3D G3DSA:3.90.550.10 329 589 5.1E-61 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16010 cbd25011fb8b4575fd4a8866b4e68797 717 Pfam PF13641 Glycosyltransferase like family 2 356 574 1.5E-37 T 28-03-2018 SMD44_RS16010 cbd25011fb8b4575fd4a8866b4e68797 717 Pfam PF01522 Polysaccharide deacetylase 66 173 1.4E-31 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS16010 cbd25011fb8b4575fd4a8866b4e68797 717 Gene3D G3DSA:3.20.20.370 48 270 7.7E-52 T 28-03-2018 SMD44_RS16010 cbd25011fb8b4575fd4a8866b4e68797 717 SUPERFAMILY SSF88713 64 262 3.95E-56 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS23150 6cebdbad8b5cef6447abd457588d720b 450 SUPERFAMILY SSF52540 231 292 3.07E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23150 6cebdbad8b5cef6447abd457588d720b 450 SUPERFAMILY SSF52540 18 189 3.07E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23150 6cebdbad8b5cef6447abd457588d720b 450 Gene3D G3DSA:3.40.50.300 8 450 1.2E-115 T 28-03-2018 SMD44_RS23150 6cebdbad8b5cef6447abd457588d720b 450 Pfam PF02374 Anion-transporting ATPase 21 294 5.6E-27 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMD44_RS27985 890a528f96b9e0dba4199cdb7c65db33 347 SUPERFAMILY SSF53474 31 311 7.32E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27985 890a528f96b9e0dba4199cdb7c65db33 347 Gene3D G3DSA:3.40.50.1820 28 320 2.3E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27985 890a528f96b9e0dba4199cdb7c65db33 347 Pfam PF12697 Alpha/beta hydrolase family 56 307 4.5E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS00710 0313dc4603c61f55555ce896fb0dd596 186 Gene3D G3DSA:3.40.630.30 1 171 7.7E-21 T 28-03-2018 SMD44_RS00710 0313dc4603c61f55555ce896fb0dd596 186 Pfam PF00583 Acetyltransferase (GNAT) family 50 143 2.8E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS00710 0313dc4603c61f55555ce896fb0dd596 186 SUPERFAMILY SSF55729 3 155 7.93E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 3.9E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 3.9E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 3.9E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 Pfam PF07568 Histidine kinase 293 363 9.2E-22 T 28-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 Gene3D G3DSA:3.30.450.20 140 283 1.7E-11 T 28-03-2018 SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 SUPERFAMILY SSF55785 176 284 4.71E-6 T 28-03-2018 IPR000014 PAS domain SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 Gene3D G3DSA:3.30.565.10 284 488 3.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 Pfam PF08448 PAS fold 174 279 3.3E-14 T 28-03-2018 IPR013656 PAS fold-4 SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 388 487 7.0E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 SUPERFAMILY SSF55874 370 487 1.44E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 Pfam PF12282 Signal transduction histidine kinase 4 147 6.6E-61 T 28-03-2018 IPR022066 Signal transduction histidine kinase SMD44_RS28395 b47a86eb634073ed196719c36f87550b 491 SMART SM00387 385 489 9.3E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06495 6c5f6b6932a40e3af8610601caf9a663 155 SUPERFAMILY SSF50475 7 150 2.32E-32 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS06495 6c5f6b6932a40e3af8610601caf9a663 155 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 100 1.4E-19 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS06495 6c5f6b6932a40e3af8610601caf9a663 155 Gene3D G3DSA:2.30.110.10 7 154 7.2E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS06155 9621ba3a1f8a43932b064ba3c8eb9837 136 Gene3D G3DSA:1.10.10.10 19 81 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06155 9621ba3a1f8a43932b064ba3c8eb9837 136 SUPERFAMILY SSF46785 19 127 3.35E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06155 9621ba3a1f8a43932b064ba3c8eb9837 136 Pfam PF03965 Penicillinase repressor 19 125 3.3E-23 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMD44_RS30035 9200f3a31fa1b5567af2624fdf32e205 489 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 10 448 1.6E-99 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMD44_RS30035 9200f3a31fa1b5567af2624fdf32e205 489 PIRSF PIRSF002744 1 469 1.4E-71 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMD44_RS15360 004f6eb76bcabdf29ff041e900689a0c 208 Pfam PF04203 Sortase family 61 202 3.1E-16 T 28-03-2018 IPR005754 Sortase family SMD44_RS15360 004f6eb76bcabdf29ff041e900689a0c 208 SUPERFAMILY SSF63817 53 202 2.16E-14 T 28-03-2018 IPR023365 Sortase domain SMD44_RS15360 004f6eb76bcabdf29ff041e900689a0c 208 Gene3D G3DSA:2.40.260.10 28 208 5.8E-24 T 28-03-2018 IPR023365 Sortase domain SMD44_RS16600 80008a90cf4e232cd552ef850d0af98c 169 SUPERFAMILY SSF55874 75 163 4.45E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16600 80008a90cf4e232cd552ef850d0af98c 169 Gene3D G3DSA:3.30.565.10 33 169 3.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16600 80008a90cf4e232cd552ef850d0af98c 169 Pfam PF13581 Histidine kinase-like ATPase domain 69 161 3.9E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28765 25d79c8bed582559b993dffe68b0fcdb 272 Pfam PF04672 S-adenosyl methyltransferase 13 272 1.0E-101 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS28765 25d79c8bed582559b993dffe68b0fcdb 272 PIRSF PIRSF017393 3 272 2.9E-100 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS28765 25d79c8bed582559b993dffe68b0fcdb 272 Gene3D G3DSA:3.40.50.150 2 272 2.5E-51 T 28-03-2018 SMD44_RS28765 25d79c8bed582559b993dffe68b0fcdb 272 SUPERFAMILY SSF53335 23 257 2.51E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS06840 c32c73c579e3a752c6c456aa8af3cf83 489 Gene3D G3DSA:3.40.50.2000 209 370 2.2E-33 T 28-03-2018 SMD44_RS06840 c32c73c579e3a752c6c456aa8af3cf83 489 Pfam PF13439 Glycosyltransferase Family 4 30 195 5.3E-15 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS06840 c32c73c579e3a752c6c456aa8af3cf83 489 Pfam PF13692 Glycosyl transferases group 1 219 353 4.1E-21 T 28-03-2018 SMD44_RS06840 c32c73c579e3a752c6c456aa8af3cf83 489 SUPERFAMILY SSF53756 21 381 4.71E-56 T 28-03-2018 SMD44_RS06840 c32c73c579e3a752c6c456aa8af3cf83 489 Gene3D G3DSA:3.40.50.2000 15 208 5.8E-10 T 28-03-2018 SMD44_RS25710 d0e0f93b833198f909f18062a27a4bf4 426 SUPERFAMILY SSF53474 134 413 5.09E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS25710 d0e0f93b833198f909f18062a27a4bf4 426 Gene3D G3DSA:3.40.50.1820 98 418 7.5E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS25710 d0e0f93b833198f909f18062a27a4bf4 426 Pfam PF12697 Alpha/beta hydrolase family 146 408 2.2E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS28255 13bd83c59bf28a510d40c767e4b18c5e 271 SUPERFAMILY SSF143081 2 261 2.49E-65 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) SMD44_RS28255 13bd83c59bf28a510d40c767e4b18c5e 271 Gene3D G3DSA:3.90.1680.10 1 269 6.4E-82 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) SMD44_RS28255 13bd83c59bf28a510d40c767e4b18c5e 271 Pfam PF02586 SOS response associated peptidase (SRAP) 1 251 4.6E-68 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) SMD44_RS09965 89d9fa982ab4807df3372a7123aa18f7 415 SUPERFAMILY SSF103473 14 393 1.57E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS09965 89d9fa982ab4807df3372a7123aa18f7 415 Pfam PF07690 Major Facilitator Superfamily 21 346 9.9E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS09965 89d9fa982ab4807df3372a7123aa18f7 415 Gene3D G3DSA:1.20.1250.20 210 407 8.6E-17 T 28-03-2018 SMD44_RS09965 89d9fa982ab4807df3372a7123aa18f7 415 Gene3D G3DSA:1.20.1250.20 11 203 2.0E-29 T 28-03-2018 SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 Gene3D G3DSA:3.40.190.10 124 203 2.3E-8 T 28-03-2018 SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 Gene3D G3DSA:1.10.10.10 29 113 3.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 71 82 4.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 4.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 71 4.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 SUPERFAMILY SSF46785 32 109 1.94E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 SUPERFAMILY SSF53850 125 328 4.19E-29 T 28-03-2018 SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 Gene3D G3DSA:3.40.190.10 204 295 4.6E-25 T 28-03-2018 SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 36 91 3.2E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03825 95264b185f6ae962eba6e07c8f42520c 330 Pfam PF03466 LysR substrate binding domain 126 326 1.0E-26 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS03105 3579f5f3d65841aeafe0f4e4eb3067ee 288 SUPERFAMILY SSF51197 2 229 3.11E-59 T 28-03-2018 SMD44_RS03105 3579f5f3d65841aeafe0f4e4eb3067ee 288 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 8 207 2.1E-34 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMD44_RS03105 3579f5f3d65841aeafe0f4e4eb3067ee 288 Gene3D G3DSA:2.60.120.620 1 219 4.6E-47 T 28-03-2018 SMD44_RS03045 37370e0886720dc3ee328574aa6171f8 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 2.7E-31 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 SUPERFAMILY SSF48264 18 412 4.98E-84 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 334 349 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 306 333 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 211 233 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 152 168 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 365 376 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 289 300 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 102 113 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 356 365 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 PRINTS PR00359 B-class P450 signature 169 184 2.2E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 Pfam PF00067 Cytochrome P450 292 382 7.8E-17 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS12460 88b4635e79a8f11e559971e9f4171f74 414 Gene3D G3DSA:1.10.630.10 13 412 4.7E-66 T 28-03-2018 SMD44_RS21345 b0b36606a62a0a881b2bf842bb40b14d 220 SMART SM00756 34 175 1.2E-55 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMD44_RS21345 b0b36606a62a0a881b2bf842bb40b14d 220 Pfam PF07884 Vitamin K epoxide reductase family 40 171 4.7E-29 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 SUPERFAMILY SSF46785 2 109 8.57E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 6.4E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 SUPERFAMILY SSF53850 83 244 2.85E-27 T 28-03-2018 SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 Gene3D G3DSA:3.40.190.10 90 170 9.5E-17 T 28-03-2018 SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 Gene3D G3DSA:1.10.10.10 2 84 1.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 Gene3D G3DSA:3.40.190.10 171 253 5.8E-13 T 28-03-2018 SMD44_RS34610 3f6f36f39cf88e7c3f9ba21fb6557c36 297 Pfam PF03466 LysR substrate binding domain 86 244 3.7E-29 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS00235 6d06d729f3ce7b93f9a4e8c6a44f90be 289 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 91 2.3E-28 T 28-03-2018 IPR025161 Putative transposase IS4/IS5 family SMD44_RS00235 6d06d729f3ce7b93f9a4e8c6a44f90be 289 Pfam PF01609 Transposase DDE domain 110 251 1.6E-12 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SMD44_RS15260 6d06d729f3ce7b93f9a4e8c6a44f90be 289 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 91 2.3E-28 T 28-03-2018 IPR025161 Putative transposase IS4/IS5 family SMD44_RS15260 6d06d729f3ce7b93f9a4e8c6a44f90be 289 Pfam PF01609 Transposase DDE domain 110 251 1.6E-12 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SMD44_RS33155 50c47f30aa25ffc982acb6766bc152d6 696 Gene3D G3DSA:3.40.50.300 418 626 9.0E-27 T 28-03-2018 SMD44_RS33155 50c47f30aa25ffc982acb6766bc152d6 696 SUPERFAMILY SSF52540 439 669 5.4E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS33155 50c47f30aa25ffc982acb6766bc152d6 696 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 488 612 5.0E-22 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS33155 50c47f30aa25ffc982acb6766bc152d6 696 SMART SM00382 483 615 1.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS35975 b583361d705976029f9dc9830ac5a0c7 288 SUPERFAMILY SSF161098 79 262 2.88E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS35975 b583361d705976029f9dc9830ac5a0c7 288 Gene3D G3DSA:1.10.3720.10 79 273 8.2E-28 T 28-03-2018 SMD44_RS35975 b583361d705976029f9dc9830ac5a0c7 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 272 3.0E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS34530 ba56ff259be5b97dbb1c524086dc71c9 233 SUPERFAMILY SSF54593 7 126 6.7E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS34530 ba56ff259be5b97dbb1c524086dc71c9 233 Gene3D G3DSA:3.10.180.10 8 170 2.4E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS11680 3ff0a77d5f5c92092b2edf9cc6021234 154 SMART SM00226 25 150 5.7E-46 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS11680 3ff0a77d5f5c92092b2edf9cc6021234 154 SUPERFAMILY SSF52788 24 148 7.33E-37 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS11680 3ff0a77d5f5c92092b2edf9cc6021234 154 Gene3D G3DSA:3.40.50.2300 23 154 2.3E-38 T 28-03-2018 SMD44_RS11680 3ff0a77d5f5c92092b2edf9cc6021234 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 27 148 2.5E-21 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS34345 54ba6d7f3420b20de38ffe835bbe4d83 144 Pfam PF00741 Gas vesicle protein 18 55 9.4E-12 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMD44_RS34345 54ba6d7f3420b20de38ffe835bbe4d83 144 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 5 92 29.349 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMD44_RS34345 54ba6d7f3420b20de38ffe835bbe4d83 144 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 51 64 - T 28-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMD44_RS34345 54ba6d7f3420b20de38ffe835bbe4d83 144 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 18 32 - T 28-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMD44_RS03735 e8d1acb283252921d5022cce8ffd1efc 111 SMART SM00418 18 98 1.2E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS03735 e8d1acb283252921d5022cce8ffd1efc 111 SUPERFAMILY SSF46785 9 98 1.26E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03735 e8d1acb283252921d5022cce8ffd1efc 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 3.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS03735 e8d1acb283252921d5022cce8ffd1efc 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 3.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS03735 e8d1acb283252921d5022cce8ffd1efc 111 Gene3D G3DSA:1.10.10.10 4 92 4.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03735 e8d1acb283252921d5022cce8ffd1efc 111 Pfam PF12840 Helix-turn-helix domain 19 73 2.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17945 bb7ffb8190d059111f71b5f3c2ab3790 158 Pfam PF04075 F420H(2)-dependent quinone reductase 36 153 1.8E-23 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD44_RS17945 bb7ffb8190d059111f71b5f3c2ab3790 158 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 46 156 6.3E-24 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD44_RS17945 bb7ffb8190d059111f71b5f3c2ab3790 158 Gene3D G3DSA:2.30.110.10 20 158 1.5E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 Gene3D G3DSA:2.40.180.10 1 363 1.7E-163 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 Pfam PF06628 Catalase-related immune-responsive 423 484 1.3E-20 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 PIRSF PIRSF038928 2 488 5.1E-220 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 SUPERFAMILY SSF56634 9 485 9.29E-206 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 SMART SM01060 13 397 1.3E-281 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 339 347 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 Pfam PF00199 Catalase 13 394 1.2E-186 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 PRINTS PR00067 Catalase signature 294 321 3.3E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 PRINTS PR00067 Catalase signature 26 49 3.3E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 PRINTS PR00067 Catalase signature 129 147 3.3E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 PRINTS PR00067 Catalase signature 326 352 3.3E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 PRINTS PR00067 Catalase signature 89 107 3.3E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 PRINTS PR00067 Catalase signature 110 127 3.3E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS28215 b1b94e418279f52555831e7242899f50 489 ProSitePatterns PS00438 Catalase proximal active site signature. 49 65 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMD44_RS17815 7328c338a1fae2d0dcf19051ebb292c2 124 Pfam PF12840 Helix-turn-helix domain 14 76 2.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17815 7328c338a1fae2d0dcf19051ebb292c2 124 SUPERFAMILY SSF46785 3 96 3.14E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17815 7328c338a1fae2d0dcf19051ebb292c2 124 Gene3D G3DSA:1.10.10.10 1 105 3.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17815 7328c338a1fae2d0dcf19051ebb292c2 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 2.4E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS17815 7328c338a1fae2d0dcf19051ebb292c2 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.4E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS17815 7328c338a1fae2d0dcf19051ebb292c2 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 2.4E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS17815 7328c338a1fae2d0dcf19051ebb292c2 124 SMART SM00418 15 96 7.4E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19690 a61ff659e8d01fb175b8ce634a3ddc56 136 SUPERFAMILY SSF52788 7 130 1.44E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS19690 a61ff659e8d01fb175b8ce634a3ddc56 136 SMART SM00226 7 132 1.3E-47 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS19690 a61ff659e8d01fb175b8ce634a3ddc56 136 Gene3D G3DSA:3.40.50.2300 5 136 2.3E-40 T 28-03-2018 SMD44_RS19690 a61ff659e8d01fb175b8ce634a3ddc56 136 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 129 6.0E-24 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS28080 3c25c6be2a7cf6bff38af89eb0a03dee 473 Gene3D G3DSA:3.40.630.10 15 213 8.4E-42 T 28-03-2018 SMD44_RS28080 3c25c6be2a7cf6bff38af89eb0a03dee 473 Gene3D G3DSA:3.30.70.360 214 377 9.6E-54 T 28-03-2018 SMD44_RS28080 3c25c6be2a7cf6bff38af89eb0a03dee 473 Pfam PF07687 Peptidase dimerisation domain 207 366 1.2E-24 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS28080 3c25c6be2a7cf6bff38af89eb0a03dee 473 SUPERFAMILY SSF53187 381 466 5.43E-63 T 28-03-2018 SMD44_RS28080 3c25c6be2a7cf6bff38af89eb0a03dee 473 SUPERFAMILY SSF53187 14 210 5.43E-63 T 28-03-2018 SMD44_RS28080 3c25c6be2a7cf6bff38af89eb0a03dee 473 Pfam PF01546 Peptidase family M20/M25/M40 94 460 1.6E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 40 1.4E-4 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 53 193 3.7E-22 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 SUPERFAMILY SSF46689 3 49 9.23E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 PRINTS PR00400 Tetracycline repressor protein signature 59 78 3.7E-6 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 PRINTS PR00400 Tetracycline repressor protein signature 8 31 3.7E-6 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 PRINTS PR00400 Tetracycline repressor protein signature 115 134 3.7E-6 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 Gene3D G3DSA:1.10.10.60 1 48 6.8E-10 T 28-03-2018 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 Gene3D G3DSA:1.10.357.10 49 195 7.4E-35 T 28-03-2018 SMD44_RS40770 6c80ea42563c62e9169401816605aa1c 201 SUPERFAMILY SSF48498 58 194 2.0E-33 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS27860 d3f67dfbed5ea2c6b980c021a6e19efe 252 SUPERFAMILY SSF88659 166 224 4.49E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS27860 d3f67dfbed5ea2c6b980c021a6e19efe 252 Pfam PF04542 Sigma-70 region 2 70 135 1.1E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS27860 d3f67dfbed5ea2c6b980c021a6e19efe 252 SUPERFAMILY SSF88946 65 147 3.45E-24 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS27860 d3f67dfbed5ea2c6b980c021a6e19efe 252 Gene3D G3DSA:1.10.10.10 133 226 5.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27860 d3f67dfbed5ea2c6b980c021a6e19efe 252 Gene3D G3DSA:1.10.1740.10 53 132 1.8E-23 T 28-03-2018 SMD44_RS27860 d3f67dfbed5ea2c6b980c021a6e19efe 252 Pfam PF08281 Sigma-70, region 4 168 219 1.4E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS27860 d3f67dfbed5ea2c6b980c021a6e19efe 252 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 66 223 2.7E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS00670 42fb1ef885625bdec996e902541f7976 392 PIRSF PIRSF016578 6 386 7.5E-66 T 28-03-2018 SMD44_RS00670 42fb1ef885625bdec996e902541f7976 392 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 238 365 5.0E-16 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMD44_RS00670 42fb1ef885625bdec996e902541f7976 392 SUPERFAMILY SSF47203 221 381 2.86E-12 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS00670 42fb1ef885625bdec996e902541f7976 392 Gene3D G3DSA:2.40.110.10 123 211 3.7E-12 T 28-03-2018 SMD44_RS00670 42fb1ef885625bdec996e902541f7976 392 SUPERFAMILY SSF56645 21 211 3.24E-24 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS00670 42fb1ef885625bdec996e902541f7976 392 Gene3D G3DSA:1.10.540.10 6 121 4.1E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS00670 42fb1ef885625bdec996e902541f7976 392 Gene3D G3DSA:1.20.140.10 212 389 3.1E-17 T 28-03-2018 SMD44_RS30345 5667096df8a6ba3acd5c85e9b66cf035 389 Gene3D G3DSA:1.20.5.620 47 119 9.7E-8 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD44_RS10680 2e570ee9ae2de83d78c1695f63302204 366 Gene3D G3DSA:1.10.220.30 22 170 4.5E-6 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical SMD44_RS10680 2e570ee9ae2de83d78c1695f63302204 366 SUPERFAMILY SSF158791 78 137 6.67E-5 T 28-03-2018 SMD44_RS03250 5911c8b61209db1cf0ad6826bfc30986 326 SUPERFAMILY SSF63829 49 306 1.31E-17 T 28-03-2018 SMD44_RS03250 5911c8b61209db1cf0ad6826bfc30986 326 Gene3D G3DSA:2.130.10.10 31 186 1.5E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS03250 5911c8b61209db1cf0ad6826bfc30986 326 Gene3D G3DSA:2.130.10.10 187 305 6.3E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS32680 85682731dc328a18d8d0676e971d3d27 416 SMART SM00631 9 240 0.0037 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS32680 85682731dc328a18d8d0676e971d3d27 416 Pfam PF00246 Zinc carboxypeptidase 18 108 4.3E-14 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS32680 85682731dc328a18d8d0676e971d3d27 416 Gene3D G3DSA:3.40.630.10 1 188 3.5E-25 T 28-03-2018 SMD44_RS32680 85682731dc328a18d8d0676e971d3d27 416 SUPERFAMILY SSF53187 8 248 1.26E-25 T 28-03-2018 SMD44_RS43445 b6589f736bf97976a3222162cff7dc2c 336 Pfam PF02467 Transcription factor WhiB 188 254 2.7E-6 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS43365 19c26c8ed2a0a67a5d8c5151f2a24919 347 Gene3D G3DSA:1.10.10.10 7 107 1.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS43365 19c26c8ed2a0a67a5d8c5151f2a24919 347 SUPERFAMILY SSF46785 20 116 5.15E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS43365 19c26c8ed2a0a67a5d8c5151f2a24919 347 Pfam PF13814 Replication-relaxation 27 226 1.0E-31 T 28-03-2018 IPR025855 Plasmid replication-relaxation SMD44_RS12245 d6fc9feb97f8c521b1bdd1986697f710 357 Pfam PF01497 Periplasmic binding protein 105 332 1.6E-27 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS12245 d6fc9feb97f8c521b1bdd1986697f710 357 SUPERFAMILY SSF53807 85 351 1.41E-62 T 28-03-2018 SMD44_RS12245 d6fc9feb97f8c521b1bdd1986697f710 357 Gene3D G3DSA:3.40.50.1980 82 206 6.5E-27 T 28-03-2018 SMD44_RS12245 d6fc9feb97f8c521b1bdd1986697f710 357 Gene3D G3DSA:3.40.50.1980 207 357 2.3E-32 T 28-03-2018 SMD44_RS35185 c9e474dc9d2501cba74cbcdfbeb7fa53 224 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 6 220 1.8E-102 T 28-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 SMD44_RS35185 c9e474dc9d2501cba74cbcdfbeb7fa53 224 Gene3D G3DSA:2.60.130.10 8 221 1.4E-61 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD44_RS35185 c9e474dc9d2501cba74cbcdfbeb7fa53 224 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 63 91 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMD44_RS35185 c9e474dc9d2501cba74cbcdfbeb7fa53 224 SUPERFAMILY SSF49482 30 220 2.22E-67 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD44_RS35185 c9e474dc9d2501cba74cbcdfbeb7fa53 224 Pfam PF00775 Dioxygenase 32 212 4.9E-56 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMD44_RS05090 267aab3534643c39623d29272c6b9f9f 493 Pfam PF01425 Amidase 27 474 2.1E-83 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS05090 267aab3534643c39623d29272c6b9f9f 493 ProSitePatterns PS00571 Amidases signature. 148 179 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMD44_RS05090 267aab3534643c39623d29272c6b9f9f 493 Gene3D G3DSA:3.90.1300.10 2 493 1.5E-121 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS05090 267aab3534643c39623d29272c6b9f9f 493 SUPERFAMILY SSF75304 3 391 7.98E-116 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS05090 267aab3534643c39623d29272c6b9f9f 493 SUPERFAMILY SSF75304 427 483 7.98E-116 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 PRINTS PR00095 Anthranilate synthase component I signature 427 441 6.6E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 PRINTS PR00095 Anthranilate synthase component I signature 442 456 6.6E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 PRINTS PR00095 Anthranilate synthase component I signature 347 360 6.6E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 PRINTS PR00095 Anthranilate synthase component I signature 333 346 6.6E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 25 494 2.2E-173 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 Gene3D G3DSA:3.60.120.10 14 497 1.3E-166 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 Pfam PF00425 chorismate binding enzyme 228 485 1.3E-98 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 168 1.4E-30 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD44_RS10800 f88b0ea1a0bfec2991c394e27cf653cb 507 SUPERFAMILY SSF56322 14 494 9.16E-158 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS39590 27bed98474bdfb3eaba2d83961b4870e 290 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.2E-122 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 SMD44_RS39590 27bed98474bdfb3eaba2d83961b4870e 290 SUPERFAMILY SSF53448 2 285 6.44E-78 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS39590 27bed98474bdfb3eaba2d83961b4870e 290 Pfam PF00483 Nucleotidyl transferase 2 236 2.2E-57 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD44_RS39590 27bed98474bdfb3eaba2d83961b4870e 290 Gene3D G3DSA:3.90.550.10 1 290 2.1E-61 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS18950 66655a833a3ada82fe1bc9582867b3df 466 Pfam PF01266 FAD dependent oxidoreductase 34 393 1.5E-51 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS18950 66655a833a3ada82fe1bc9582867b3df 466 Gene3D G3DSA:3.30.9.10 229 354 2.0E-18 T 28-03-2018 SMD44_RS18950 66655a833a3ada82fe1bc9582867b3df 466 SUPERFAMILY SSF51905 182 308 1.01E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS18950 66655a833a3ada82fe1bc9582867b3df 466 SUPERFAMILY SSF51905 13 127 1.01E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS18950 66655a833a3ada82fe1bc9582867b3df 466 Gene3D G3DSA:3.50.50.60 10 228 1.3E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS39425 5a3bb77cb2bf93bfbba5c79fa3fc0574 424 Pfam PF07690 Major Facilitator Superfamily 23 365 1.1E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS39425 5a3bb77cb2bf93bfbba5c79fa3fc0574 424 Gene3D G3DSA:1.20.1250.20 16 208 8.9E-15 T 28-03-2018 SMD44_RS39425 5a3bb77cb2bf93bfbba5c79fa3fc0574 424 Gene3D G3DSA:1.20.1250.20 209 414 1.4E-12 T 28-03-2018 SMD44_RS39425 5a3bb77cb2bf93bfbba5c79fa3fc0574 424 SUPERFAMILY SSF103473 20 408 1.57E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17450 824e8c9c783be493a745135999f1cf64 380 SUPERFAMILY SSF50249 5 78 3.6E-7 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS17450 824e8c9c783be493a745135999f1cf64 380 Gene3D G3DSA:3.40.50.300 60 318 3.7E-57 T 28-03-2018 SMD44_RS17450 824e8c9c783be493a745135999f1cf64 380 Pfam PF07497 Rho termination factor, RNA-binding domain 8 78 2.9E-11 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 SMD44_RS17450 824e8c9c783be493a745135999f1cf64 380 SUPERFAMILY SSF52540 74 325 1.09E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS17450 824e8c9c783be493a745135999f1cf64 380 Gene3D G3DSA:2.40.50.140 5 59 4.8E-14 T 28-03-2018 SMD44_RS17450 824e8c9c783be493a745135999f1cf64 380 SMART SM00382 124 309 2.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS17450 824e8c9c783be493a745135999f1cf64 380 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 113 317 7.9E-21 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD44_RS17450 824e8c9c783be493a745135999f1cf64 380 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 373 158.488 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SMD44_RS25875 d1064bb9debe5bf1609fb4c5cc477ab5 608 Pfam PF00732 GMC oxidoreductase 17 297 6.6E-11 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS25875 d1064bb9debe5bf1609fb4c5cc477ab5 608 Pfam PF05199 GMC oxidoreductase 496 553 5.4E-13 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS25875 d1064bb9debe5bf1609fb4c5cc477ab5 608 Gene3D G3DSA:3.50.50.60 1 576 4.8E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25875 d1064bb9debe5bf1609fb4c5cc477ab5 608 SUPERFAMILY SSF51905 498 558 8.75E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25875 d1064bb9debe5bf1609fb4c5cc477ab5 608 SUPERFAMILY SSF51905 15 173 8.75E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25875 d1064bb9debe5bf1609fb4c5cc477ab5 608 SUPERFAMILY SSF51905 207 322 8.75E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS16355 e4b76b29c7f7ca8e07bfddfd73c0f898 335 Pfam PF01944 Stage II sporulation protein M 108 283 3.7E-35 T 28-03-2018 IPR002798 Stage II sporulation protein M-like SMD44_RS30200 2d53c6aaffad6e4c87f7fc6fd57cd5dc 265 Gene3D G3DSA:3.90.850.10 38 265 1.7E-87 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS30200 2d53c6aaffad6e4c87f7fc6fd57cd5dc 265 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 64 261 1.9E-71 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS30200 2d53c6aaffad6e4c87f7fc6fd57cd5dc 265 SUPERFAMILY SSF56529 56 262 8.11E-79 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS30200 2d53c6aaffad6e4c87f7fc6fd57cd5dc 265 Pfam PF10370 Domain of unknown function (DUF2437) 2 59 2.0E-11 T 28-03-2018 IPR018833 Domain of unknown function DUF2437 SMD44_RS18210 f9d495407c3ab984fa86dcb9cf7d74cd 362 Gene3D G3DSA:1.10.101.10 116 184 3.4E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS18210 f9d495407c3ab984fa86dcb9cf7d74cd 362 Pfam PF13437 HlyD family secretion protein 186 281 3.7E-7 T 28-03-2018 SMD44_RS18210 f9d495407c3ab984fa86dcb9cf7d74cd 362 Pfam PF01471 Putative peptidoglycan binding domain 130 178 1.7E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS18210 f9d495407c3ab984fa86dcb9cf7d74cd 362 SUPERFAMILY SSF47090 116 180 4.19E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 Gene3D G3DSA:3.40.50.620 6 638 9.8E-128 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 Gene3D G3DSA:1.10.730.10 641 825 1.3E-43 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 1.7E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 1.7E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 45 56 1.7E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 559 568 1.7E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 1.7E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 9 838 4.3E-272 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 SUPERFAMILY SSF52374 394 648 2.7E-122 T 28-03-2018 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 SUPERFAMILY SSF52374 9 202 2.7E-122 T 28-03-2018 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 SUPERFAMILY SSF50677 205 394 1.88E-46 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 Pfam PF08264 Anticodon-binding domain of tRNA 687 832 2.7E-30 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 22 628 1.6E-168 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 7 1045 13.813 T 28-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD44_RS10985 9ee1d2fb312d2e51f6e7d35fd3fa33b9 1047 SUPERFAMILY SSF47323 655 892 2.43E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS24010 3fea576294846292e397db3a4efd549b 119 Gene3D G3DSA:2.30.30.410 28 117 1.4E-10 T 28-03-2018 SMD44_RS24010 3fea576294846292e397db3a4efd549b 119 Pfam PF08239 Bacterial SH3 domain 50 107 3.3E-8 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type SMD44_RS25585 4055d2d41edfab4cde0ec9d813d16158 127 Gene3D G3DSA:3.30.420.100 1 127 3.7E-40 T 28-03-2018 SMD44_RS25585 4055d2d41edfab4cde0ec9d813d16158 127 SUPERFAMILY SSF53137 14 125 8.5E-48 T 28-03-2018 SMD44_RS25585 4055d2d41edfab4cde0ec9d813d16158 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 26.655 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25585 4055d2d41edfab4cde0ec9d813d16158 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 15 127 2.8E-40 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25585 4055d2d41edfab4cde0ec9d813d16158 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 13 127 1.2E-49 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS01425 1c07dbf9f77bcb075d7cdc1f219607c8 217 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 164 2.6E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS01425 1c07dbf9f77bcb075d7cdc1f219607c8 217 Gene3D G3DSA:1.10.1740.10 1 74 5.7E-17 T 28-03-2018 SMD44_RS01425 1c07dbf9f77bcb075d7cdc1f219607c8 217 Gene3D G3DSA:1.10.10.10 75 167 1.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01425 1c07dbf9f77bcb075d7cdc1f219607c8 217 Pfam PF08281 Sigma-70, region 4 113 163 4.6E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS01425 1c07dbf9f77bcb075d7cdc1f219607c8 217 Pfam PF04542 Sigma-70 region 2 10 78 1.0E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS01425 1c07dbf9f77bcb075d7cdc1f219607c8 217 SUPERFAMILY SSF88659 91 165 4.11E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS01425 1c07dbf9f77bcb075d7cdc1f219607c8 217 SUPERFAMILY SSF88946 3 81 2.33E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS14090 8f48ec18d65e38be7e8d810a8cfd0327 499 Gene3D G3DSA:3.30.565.10 260 336 1.4E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14090 8f48ec18d65e38be7e8d810a8cfd0327 499 Pfam PF01391 Collagen triple helix repeat (20 copies) 347 399 5.6E-7 T 28-03-2018 IPR008160 Collagen triple helix repeat SMD44_RS14090 8f48ec18d65e38be7e8d810a8cfd0327 499 Pfam PF07730 Histidine kinase 191 246 8.9E-8 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS14090 8f48ec18d65e38be7e8d810a8cfd0327 499 SUPERFAMILY SSF55874 267 334 1.11E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS14090 8f48ec18d65e38be7e8d810a8cfd0327 499 Gene3D G3DSA:2.160.20.50 337 443 2.9E-5 T 28-03-2018 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 SUPERFAMILY SSF52402 3 165 3.97E-42 T 28-03-2018 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 SUPERFAMILY SSF69864 171 394 2.88E-84 T 28-03-2018 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 Gene3D G3DSA:3.90.1260.10 162 352 1.4E-74 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 Gene3D G3DSA:1.20.5.470 362 394 4.8E-10 T 28-03-2018 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 Pfam PF00764 Arginosuccinate synthase 6 391 2.4E-185 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 Gene3D G3DSA:3.40.50.620 3 161 5.7E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 392 4.1E-147 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS07750 b94657bfe3f53e4026f26f98d1196565 397 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 52.163 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD44_RS13205 7dc67e02f1a6f33cf28d84871f50ba94 134 SUPERFAMILY SSF46785 19 127 2.03E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13205 7dc67e02f1a6f33cf28d84871f50ba94 134 Pfam PF03965 Penicillinase repressor 19 126 1.7E-21 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMD44_RS13205 7dc67e02f1a6f33cf28d84871f50ba94 134 Gene3D G3DSA:1.10.10.10 19 81 1.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16170 16a3cf2be4b12bcb98704e7e731a4a10 213 Gene3D G3DSA:1.10.10.60 29 76 3.7E-13 T 28-03-2018 SMD44_RS16170 16a3cf2be4b12bcb98704e7e731a4a10 213 SUPERFAMILY SSF46689 28 82 3.34E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS16170 16a3cf2be4b12bcb98704e7e731a4a10 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 46 77 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS16170 16a3cf2be4b12bcb98704e7e731a4a10 213 Gene3D G3DSA:1.10.357.10 77 213 7.4E-17 T 28-03-2018 SMD44_RS16170 16a3cf2be4b12bcb98704e7e731a4a10 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 78 2.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS16170 16a3cf2be4b12bcb98704e7e731a4a10 213 Pfam PF16859 Bacterial transcriptional repressor C-terminal 92 204 1.2E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS16170 16a3cf2be4b12bcb98704e7e731a4a10 213 SUPERFAMILY SSF48498 92 209 4.45E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS09475 00120568ee49173e79a9c46a8db9c5a4 265 Gene3D G3DSA:2.40.400.10 9 238 3.5E-40 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 SMD44_RS09475 00120568ee49173e79a9c46a8db9c5a4 265 Pfam PF06314 Acetoacetate decarboxylase (ADC) 19 225 3.3E-44 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 SMD44_RS09475 00120568ee49173e79a9c46a8db9c5a4 265 SUPERFAMILY SSF160104 28 224 3.79E-42 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 SMD44_RS37295 1a46224b7865deeeb32a77750a36f480 481 PIRSF PIRSF006060 13 480 1.0E-87 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS37295 1a46224b7865deeeb32a77750a36f480 481 Pfam PF13520 Amino acid permease 35 439 5.4E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS37470 8121aea40b3a02b49671e428b0d7f0a8 322 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 316 8.8E-116 T 28-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 SMD44_RS37470 8121aea40b3a02b49671e428b0d7f0a8 322 SUPERFAMILY SSF53335 229 237 2.0E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS37470 8121aea40b3a02b49671e428b0d7f0a8 322 SUPERFAMILY SSF53335 282 307 2.0E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS37470 8121aea40b3a02b49671e428b0d7f0a8 322 SUPERFAMILY SSF53335 29 192 2.0E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS37470 8121aea40b3a02b49671e428b0d7f0a8 322 PIRSF PIRSF018005 5 320 1.1E-138 T 28-03-2018 IPR017804 Methyltransferase EgtD-like SMD44_RS37470 8121aea40b3a02b49671e428b0d7f0a8 322 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 319 55.774 T 28-03-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 SMD44_RS37470 8121aea40b3a02b49671e428b0d7f0a8 322 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 19 317 5.1E-113 T 28-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent SMD44_RS37470 8121aea40b3a02b49671e428b0d7f0a8 322 Gene3D G3DSA:3.40.50.150 19 319 1.5E-21 T 28-03-2018 SMD44_RS42560 c333f22a7837c10104d8552943f18def 423 SUPERFAMILY SSF103473 21 406 7.85E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS42560 c333f22a7837c10104d8552943f18def 423 Pfam PF07690 Major Facilitator Superfamily 31 308 5.9E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS42560 c333f22a7837c10104d8552943f18def 423 Gene3D G3DSA:1.20.1250.20 12 201 8.7E-31 T 28-03-2018 SMD44_RS42560 c333f22a7837c10104d8552943f18def 423 Gene3D G3DSA:1.20.1250.20 219 418 2.3E-11 T 28-03-2018 SMD44_RS09985 b7b4bd400ce2cb734c70b6571bab0097 115 Gene3D G3DSA:3.30.300.130 13 110 5.9E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SMD44_RS09985 b7b4bd400ce2cb734c70b6571bab0097 115 Pfam PF01883 Iron-sulfur cluster assembly protein 17 78 3.8E-19 T 28-03-2018 IPR002744 MIP18 family-like SMD44_RS09985 b7b4bd400ce2cb734c70b6571bab0097 115 SUPERFAMILY SSF117916 15 109 6.54E-28 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SMD44_RS08830 5f5d69c91575601d1c2199a85ef9d189 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 18 40 9.6E-9 T 28-03-2018 SMD44_RS08830 5f5d69c91575601d1c2199a85ef9d189 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 9.6E-9 T 28-03-2018 SMD44_RS08830 5f5d69c91575601d1c2199a85ef9d189 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 165 180 9.6E-9 T 28-03-2018 SMD44_RS08830 5f5d69c91575601d1c2199a85ef9d189 410 Gene3D G3DSA:3.50.50.60 18 363 8.9E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08830 5f5d69c91575601d1c2199a85ef9d189 410 Pfam PF01494 FAD binding domain 18 354 3.0E-16 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS08830 5f5d69c91575601d1c2199a85ef9d189 410 SUPERFAMILY SSF51905 19 186 8.46E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS08830 5f5d69c91575601d1c2199a85ef9d189 410 SUPERFAMILY SSF51905 285 391 8.46E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 193 388 1.9E-52 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 SUPERFAMILY SSF52402 192 392 2.01E-39 T 28-03-2018 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 Pfam PF02926 THUMP domain 90 180 5.5E-13 T 28-03-2018 IPR004114 THUMP domain GO:0003723 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 SMART SM00981 90 183 4.2E-15 T 28-03-2018 IPR004114 THUMP domain GO:0003723 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 Gene3D G3DSA:3.30.70.1510 21 97 2.6E-15 T 28-03-2018 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 SUPERFAMILY SSF143437 21 191 4.71E-36 T 28-03-2018 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 426 109.31 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 Gene3D G3DSA:3.30.2300.10 103 180 1.1E-15 T 28-03-2018 SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 Gene3D G3DSA:3.40.50.620 193 404 3.4E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS01090 7ae130e1d825896dc72f38db17684ad6 426 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 22 392 2.1E-90 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 SMD44_RS00495 1b88c91e20ee08c8ae47e8e388e41490 145 Gene3D G3DSA:2.40.50.140 68 144 4.4E-18 T 28-03-2018 SMD44_RS00495 1b88c91e20ee08c8ae47e8e388e41490 145 SUPERFAMILY SSF141322 78 138 2.35E-6 T 28-03-2018 SMD44_RS00495 1b88c91e20ee08c8ae47e8e388e41490 145 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 140 1.2E-16 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain SMD44_RS00550 af8b2feef4e10bb490c41f525278c5eb 160 Gene3D G3DSA:2.30.220.10 2 51 6.3E-4 T 28-03-2018 SMD44_RS00275 23c09f627fd32fb618b68667378f261d 418 SMART SM01209 108 283 9.9E-5 T 28-03-2018 SMD44_RS00275 23c09f627fd32fb618b68667378f261d 418 Gene3D G3DSA:3.40.50.20 2 116 1.7E-5 T 28-03-2018 SMD44_RS00275 23c09f627fd32fb618b68667378f261d 418 Gene3D G3DSA:3.30.1490.20 117 191 5.0E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS00275 23c09f627fd32fb618b68667378f261d 418 SUPERFAMILY SSF56059 101 312 3.54E-39 T 28-03-2018 SMD44_RS00275 23c09f627fd32fb618b68667378f261d 418 Pfam PF13535 ATP-grasp domain 145 285 5.5E-19 T 28-03-2018 SMD44_RS00275 23c09f627fd32fb618b68667378f261d 418 Gene3D G3DSA:3.30.470.20 192 402 2.9E-26 T 28-03-2018 SMD44_RS39385 92c256f405f25762c70e8a6ae22a122f 142 Gene3D G3DSA:2.30.110.10 1 139 7.5E-29 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS39385 92c256f405f25762c70e8a6ae22a122f 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 135 9.3E-40 T 28-03-2018 IPR019920 F420-binding domain, putative SMD44_RS39385 92c256f405f25762c70e8a6ae22a122f 142 SUPERFAMILY SSF50475 3 136 4.75E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS39385 92c256f405f25762c70e8a6ae22a122f 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 91 2.5E-18 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS21610 6bbc18e50a7c1bf1724b9a3de6e7a6c9 699 Gene3D G3DSA:2.160.20.50 109 296 0.12 T 28-03-2018 SMD44_RS21610 6bbc18e50a7c1bf1724b9a3de6e7a6c9 699 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 385 657 2.0E-38 T 28-03-2018 IPR003776 YcaO-like domain SMD44_RS07470 99c9348dcfb6aa09a1c1e36d7a111b06 307 PIRSF PIRSF029271 8 307 5.3E-150 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07470 99c9348dcfb6aa09a1c1e36d7a111b06 307 SUPERFAMILY SSF51366 31 277 5.65E-63 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD44_RS07470 99c9348dcfb6aa09a1c1e36d7a111b06 307 Gene3D G3DSA:3.20.20.70 272 307 0.45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS07470 99c9348dcfb6aa09a1c1e36d7a111b06 307 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 22 307 2.2E-143 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07470 99c9348dcfb6aa09a1c1e36d7a111b06 307 Pfam PF01680 SOR/SNZ family 20 225 2.7E-107 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07470 99c9348dcfb6aa09a1c1e36d7a111b06 307 ProSitePatterns PS01235 PdxS/SNZ family signature. 218 236 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07470 99c9348dcfb6aa09a1c1e36d7a111b06 307 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 17 307 52.002 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD44_RS07470 99c9348dcfb6aa09a1c1e36d7a111b06 307 Gene3D G3DSA:3.20.20.70 31 271 1.2E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS39985 5190fed5688cc7ab0ad3e984f423aa3b 366 Pfam PF16113 Enoyl-CoA hydratase/isomerase 27 345 3.1E-125 T 28-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 SMD44_RS39985 5190fed5688cc7ab0ad3e984f423aa3b 366 Gene3D G3DSA:3.90.226.10 4 339 5.2E-96 T 28-03-2018 SMD44_RS39985 5190fed5688cc7ab0ad3e984f423aa3b 366 SUPERFAMILY SSF52096 15 206 8.48E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS39985 5190fed5688cc7ab0ad3e984f423aa3b 366 SUPERFAMILY SSF52096 258 328 8.48E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS08185 e534a37cf9c5ecb1e6fcfc6c5af46aa0 300 PIRSF PIRSF017269 7 277 5.1E-85 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 SMD44_RS08185 e534a37cf9c5ecb1e6fcfc6c5af46aa0 300 Gene3D G3DSA:3.40.50.150 76 273 2.0E-36 T 28-03-2018 SMD44_RS08185 e534a37cf9c5ecb1e6fcfc6c5af46aa0 300 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 80 243 3.6E-21 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 SMD44_RS08185 e534a37cf9c5ecb1e6fcfc6c5af46aa0 300 Gene3D G3DSA:3.10.330.20 8 74 8.3E-26 T 28-03-2018 SMD44_RS08185 e534a37cf9c5ecb1e6fcfc6c5af46aa0 300 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 11 61 3.0E-28 T 28-03-2018 SMD44_RS08185 e534a37cf9c5ecb1e6fcfc6c5af46aa0 300 SUPERFAMILY SSF53335 13 266 2.0E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS30060 51494074447db652720798a7c06713b2 364 SUPERFAMILY SSF63825 260 346 8.11E-5 T 28-03-2018 SMD44_RS30060 51494074447db652720798a7c06713b2 364 Gene3D G3DSA:2.120.10.60 263 358 8.5E-7 T 28-03-2018 SMD44_RS30060 51494074447db652720798a7c06713b2 364 Gene3D G3DSA:2.140.10.30 30 262 1.4E-18 T 28-03-2018 SMD44_RS30060 51494074447db652720798a7c06713b2 364 SUPERFAMILY SSF69304 67 282 2.88E-19 T 28-03-2018 SMD44_RS33845 86131a3e9f02d9a5a89f3585548ff64b 385 Pfam PF07786 Protein of unknown function (DUF1624) 3 199 7.1E-8 T 28-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 SMD44_RS33845 86131a3e9f02d9a5a89f3585548ff64b 385 Pfam PF04235 Protein of unknown function (DUF418) 274 378 7.7E-10 T 28-03-2018 IPR007349 Domain of unknown function DUF418 SMD44_RS40765 d920c7d6057a4c55bb5ce932dd1b9a28 238 Gene3D G3DSA:3.40.50.720 3 235 2.5E-17 T 28-03-2018 SMD44_RS40765 d920c7d6057a4c55bb5ce932dd1b9a28 238 SUPERFAMILY SSF51735 7 221 3.68E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS40765 d920c7d6057a4c55bb5ce932dd1b9a28 238 Pfam PF13460 NAD(P)H-binding 13 210 1.1E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS00535 841af05d95ace384a92d92d1e87308d2 354 Pfam PF13556 PucR C-terminal helix-turn-helix domain 285 341 2.4E-15 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS12985 7e5f5cd5189c3f233d66afea98821088 374 SUPERFAMILY SSF52540 57 125 2.02E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS12985 7e5f5cd5189c3f233d66afea98821088 374 SUPERFAMILY SSF52540 191 354 2.02E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS12985 7e5f5cd5189c3f233d66afea98821088 374 SMART SM00382 72 292 2.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS12985 7e5f5cd5189c3f233d66afea98821088 374 Gene3D G3DSA:3.40.50.300 52 321 1.6E-27 T 28-03-2018 SMD44_RS12985 7e5f5cd5189c3f233d66afea98821088 374 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 365 374 9.5E-6 T 28-03-2018 SMD44_RS12985 7e5f5cd5189c3f233d66afea98821088 374 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 80 99 9.5E-6 T 28-03-2018 SMD44_RS12985 7e5f5cd5189c3f233d66afea98821088 374 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 76 106 2.4E-4 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS00945 13ad2328260f2c4d052b37d6fde6b998 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 1.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS00945 13ad2328260f2c4d052b37d6fde6b998 232 SMART SM00448 4 115 1.2E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS00945 13ad2328260f2c4d052b37d6fde6b998 232 Pfam PF00072 Response regulator receiver domain 7 115 1.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS00945 13ad2328260f2c4d052b37d6fde6b998 232 Gene3D G3DSA:1.10.10.10 122 231 2.6E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00945 13ad2328260f2c4d052b37d6fde6b998 232 Gene3D G3DSA:3.40.50.2300 1 121 4.4E-34 T 28-03-2018 SMD44_RS00945 13ad2328260f2c4d052b37d6fde6b998 232 SUPERFAMILY SSF52172 3 171 1.85E-38 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS00945 13ad2328260f2c4d052b37d6fde6b998 232 SMART SM00862 149 227 9.1E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 Pfam PF13286 Phosphohydrolase-associated domain 339 426 2.8E-13 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 SUPERFAMILY SSF109604 327 396 1.85E-48 T 28-03-2018 SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 SUPERFAMILY SSF109604 204 252 1.85E-48 T 28-03-2018 SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 SUPERFAMILY SSF109604 283 293 1.85E-48 T 28-03-2018 SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 SUPERFAMILY SSF109604 25 172 1.85E-48 T 28-03-2018 SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 SMART SM00471 59 233 1.0E-10 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 Pfam PF01966 HD domain 63 222 4.0E-13 T 28-03-2018 IPR006674 HD domain SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 26 428 2.1E-61 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 Gene3D G3DSA:1.10.3210.10 3 215 1.4E-50 T 28-03-2018 SMD44_RS02520 451fa2a07a2a0c8c325adf8ea0c40abf 441 Gene3D G3DSA:1.10.3410.10 216 359 5.3E-13 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain SMD44_RS12445 da374587cb33ba56a4611db3d97f88e7 287 PIRSF PIRSF037395 19 283 6.1E-112 T 28-03-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 SMD44_RS12445 da374587cb33ba56a4611db3d97f88e7 287 Pfam PF12822 ECF transporter, substrate-specific component 90 259 3.6E-19 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 SMD44_RS10730 671aa1cfc4756245309ff3845d39c56a 398 Gene3D G3DSA:1.10.4080.10 17 386 5.8E-61 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10730 671aa1cfc4756245309ff3845d39c56a 398 SUPERFAMILY SSF101478 19 256 4.97E-44 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10730 671aa1cfc4756245309ff3845d39c56a 398 SUPERFAMILY SSF101478 288 359 4.97E-44 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10730 671aa1cfc4756245309ff3845d39c56a 398 Pfam PF03747 ADP-ribosylglycohydrolase 26 347 5.9E-47 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS30475 da687171ccd63e90f3c8bd367efa6d03 144 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 5.2E-32 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30475 da687171ccd63e90f3c8bd367efa6d03 144 SUPERFAMILY SSF54565 2 91 5.1E-34 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30475 da687171ccd63e90f3c8bd367efa6d03 144 Pfam PF00886 Ribosomal protein S16 9 67 3.8E-24 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30475 da687171ccd63e90f3c8bd367efa6d03 144 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.556 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS30475 da687171ccd63e90f3c8bd367efa6d03 144 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 28-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS30475 da687171ccd63e90f3c8bd367efa6d03 144 Gene3D G3DSA:3.30.1320.10 2 85 5.0E-32 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS01305 c7f8c03b3a68cb1b6f9435ddeddbd2c3 246 SUPERFAMILY SSF51735 1 212 9.18E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01305 c7f8c03b3a68cb1b6f9435ddeddbd2c3 246 Gene3D G3DSA:3.40.50.720 1 241 2.9E-18 T 28-03-2018 SMD44_RS01305 c7f8c03b3a68cb1b6f9435ddeddbd2c3 246 Pfam PF13460 NAD(P)H-binding 7 174 9.1E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS37825 8a365d49ea218694bb6f37fbddd3eb9b 133 SUPERFAMILY SSF54593 8 128 6.46E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS37825 8a365d49ea218694bb6f37fbddd3eb9b 133 Gene3D G3DSA:3.10.180.10 7 123 3.2E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS14845 17a1ec9a9f30d701b3d44b56a13691d4 273 SUPERFAMILY SSF51658 1 268 5.37E-46 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS14845 17a1ec9a9f30d701b3d44b56a13691d4 273 Pfam PF01261 Xylose isomerase-like TIM barrel 19 219 6.7E-33 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS14845 17a1ec9a9f30d701b3d44b56a13691d4 273 Gene3D G3DSA:3.20.20.150 1 273 3.7E-54 T 28-03-2018 SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 Pfam PF12419 SNF2 Helicase protein 2 139 3.5E-31 T 28-03-2018 IPR022138 Helicase SWF/SNF-related SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 SMART SM00487 180 358 6.3E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 SUPERFAMILY SSF52540 170 392 2.27E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 SUPERFAMILY SSF52540 399 655 7.69E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 SMART SM00490 516 598 1.1E-23 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 Pfam PF00176 SNF2 family N-terminal domain 203 460 1.7E-48 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 Pfam PF00271 Helicase conserved C-terminal domain 488 598 5.5E-18 T 28-03-2018 IPR001650 Helicase, C-terminal SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 Gene3D G3DSA:3.40.50.10810 162 391 9.0E-50 T 28-03-2018 SMD44_RS10395 ae39ea57fbd2c9c040e3d8f652f2e954 659 Gene3D G3DSA:3.40.50.300 477 636 1.8E-39 T 28-03-2018 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 Gene3D G3DSA:1.10.230.10 256 345 9.5E-22 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 PIRSF PIRSF001369 11 389 4.1E-95 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 PRINTS PR00143 Citrate synthase signature 142 155 4.0E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 PRINTS PR00143 Citrate synthase signature 191 206 4.0E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 PRINTS PR00143 Citrate synthase signature 266 286 4.0E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 PRINTS PR00143 Citrate synthase signature 325 341 4.0E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 PRINTS PR00143 Citrate synthase signature 345 359 4.0E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 PRINTS PR00143 Citrate synthase signature 213 241 4.0E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 ProSitePatterns PS00480 Citrate synthase signature. 273 285 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 Gene3D G3DSA:1.10.580.10 6 255 1.9E-71 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 SUPERFAMILY SSF48256 16 387 7.46E-102 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS31595 4e6177e2c349df662f6d804420b5f9e0 395 Pfam PF00285 Citrate synthase, C-terminal domain 19 375 1.2E-100 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 SMD44_RS13605 be748edcd9ba4a14246b4352ec3e3f9a 126 Gene3D G3DSA:2.30.30.410 28 126 0.001 T 28-03-2018 SMD44_RS25880 90b93e11f0d977946e30ae90509bb49d 382 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 341 376 0.0025 T 28-03-2018 SMD44_RS14655 d037b16ef11d2caa51e1fa89de7a54da 575 SUPERFAMILY SSF53756 156 361 5.96E-7 T 28-03-2018 SMD44_RS14655 d037b16ef11d2caa51e1fa89de7a54da 575 Gene3D G3DSA:3.40.50.2000 218 358 2.0E-5 T 28-03-2018 SMD44_RS33755 b881bf8854af76415c1a511a8f3fcce9 143 Gene3D G3DSA:3.40.630.30 1 140 1.1E-4 T 28-03-2018 SMD44_RS26090 96e644cb1891e4f8dfff9762da92b1da 203 Pfam PF13560 Helix-turn-helix domain 22 81 8.7E-12 T 28-03-2018 SMD44_RS26090 96e644cb1891e4f8dfff9762da92b1da 203 Gene3D G3DSA:1.10.260.40 16 84 6.7E-9 T 28-03-2018 SMD44_RS26090 96e644cb1891e4f8dfff9762da92b1da 203 SUPERFAMILY SSF47413 21 77 1.03E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS00630 30828a46eb0b1c3c011f5074552882c0 390 SUPERFAMILY SSF55874 279 377 1.92E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS00630 30828a46eb0b1c3c011f5074552882c0 390 Gene3D G3DSA:3.30.565.10 250 384 1.9E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS00630 30828a46eb0b1c3c011f5074552882c0 390 SMART SM00387 288 379 8.7E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS00630 30828a46eb0b1c3c011f5074552882c0 390 Pfam PF07730 Histidine kinase 181 245 3.0E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS31150 77e54bb8eacd9ff837f8d922120fb473 124 SUPERFAMILY SSF47413 3 73 1.18E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS31150 77e54bb8eacd9ff837f8d922120fb473 124 SMART SM00530 11 66 1.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS31150 77e54bb8eacd9ff837f8d922120fb473 124 Gene3D G3DSA:1.10.260.40 2 77 5.4E-15 T 28-03-2018 SMD44_RS31150 77e54bb8eacd9ff837f8d922120fb473 124 Pfam PF13560 Helix-turn-helix domain 8 65 3.5E-11 T 28-03-2018 SMD44_RS34950 e930cc4d921ca3d6ad68a8bf0c33d5c7 366 Gene3D G3DSA:3.20.20.70 12 352 1.8E-28 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS34950 e930cc4d921ca3d6ad68a8bf0c33d5c7 366 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 25 36 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 SMD44_RS34950 e930cc4d921ca3d6ad68a8bf0c33d5c7 366 Pfam PF04055 Radical SAM superfamily 25 191 2.6E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS34950 e930cc4d921ca3d6ad68a8bf0c33d5c7 366 SUPERFAMILY SSF102114 17 331 3.92E-39 T 28-03-2018 SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 Gene3D G3DSA:1.25.40.10 651 805 1.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 Gene3D G3DSA:1.25.40.10 553 650 0.027 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 PRINTS PR00364 Disease resistance protein signature 250 264 4.2E-8 T 28-03-2018 SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 PRINTS PR00364 Disease resistance protein signature 337 351 4.2E-8 T 28-03-2018 SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 PRINTS PR00364 Disease resistance protein signature 168 183 4.2E-8 T 28-03-2018 SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 SUPERFAMILY SSF48452 639 747 3.04E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 Pfam PF00931 NB-ARC domain 165 351 2.4E-9 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 SUPERFAMILY SSF52540 136 398 1.08E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14660 957926eeee0a464df13092e1afa0f6ed 813 Gene3D G3DSA:3.40.50.300 125 288 1.1E-13 T 28-03-2018 SMD44_RS03690 3189a47a4cb0a064532464c469aa9a08 339 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 38 74 1.4E-8 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS03690 3189a47a4cb0a064532464c469aa9a08 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 145 336 3.3E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS03690 3189a47a4cb0a064532464c469aa9a08 339 SUPERFAMILY SSF161098 122 320 1.18E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS03690 3189a47a4cb0a064532464c469aa9a08 339 Gene3D G3DSA:1.10.3720.10 42 327 7.2E-52 T 28-03-2018 SMD44_RS38345 9c2c546672f4d352be030fc6a554e949 531 Gene3D G3DSA:3.90.76.10 62 155 8.3E-31 T 28-03-2018 SMD44_RS38345 9c2c546672f4d352be030fc6a554e949 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 435 2.7E-88 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS38345 9c2c546672f4d352be030fc6a554e949 531 PIRSF PIRSF002741 1 524 2.1E-106 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS38345 9c2c546672f4d352be030fc6a554e949 531 Gene3D G3DSA:3.40.190.10 156 289 3.4E-34 T 28-03-2018 SMD44_RS38345 9c2c546672f4d352be030fc6a554e949 531 Gene3D G3DSA:3.10.105.10 290 491 4.2E-43 T 28-03-2018 SMD44_RS38345 9c2c546672f4d352be030fc6a554e949 531 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 85 107 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site SMD44_RS38345 9c2c546672f4d352be030fc6a554e949 531 SUPERFAMILY SSF53850 42 505 3.08E-119 T 28-03-2018 SMD44_RS15475 d8dc1cca5f612f883d8e2b659d4f8354 282 Pfam PF04203 Sortase family 140 276 1.1E-25 T 28-03-2018 IPR005754 Sortase family SMD44_RS15475 d8dc1cca5f612f883d8e2b659d4f8354 282 TIGRFAM TIGR01076 sortase_fam: sortase 139 275 6.4E-13 T 28-03-2018 IPR005754 Sortase family SMD44_RS15475 d8dc1cca5f612f883d8e2b659d4f8354 282 SUPERFAMILY SSF63817 131 280 5.36E-31 T 28-03-2018 IPR023365 Sortase domain SMD44_RS15475 d8dc1cca5f612f883d8e2b659d4f8354 282 Gene3D G3DSA:2.40.260.10 51 282 2.8E-41 T 28-03-2018 IPR023365 Sortase domain SMD44_RS42350 5b82ded72b984f7299e6e2b2ff46099d 112 Pfam PF00216 Bacterial DNA-binding protein 1 87 6.0E-24 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS42350 5b82ded72b984f7299e6e2b2ff46099d 112 SMART SM00411 1 90 8.9E-25 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS42350 5b82ded72b984f7299e6e2b2ff46099d 112 SUPERFAMILY SSF47729 1 91 1.4E-22 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD44_RS42350 5b82ded72b984f7299e6e2b2ff46099d 112 Gene3D G3DSA:4.10.520.10 1 92 6.6E-24 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD44_RS42350 5b82ded72b984f7299e6e2b2ff46099d 112 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 7.1E-6 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS42350 5b82ded72b984f7299e6e2b2ff46099d 112 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 7.1E-6 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS42350 5b82ded72b984f7299e6e2b2ff46099d 112 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 7.1E-6 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD44_RS16225 c38eeb299bd8a9cae3639c741f2de5d8 176 Pfam PF04138 GtrA-like protein 37 156 2.7E-18 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 Pfam PF03453 MoeA N-terminal region (domain I and II) 18 200 5.6E-46 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 Gene3D G3DSA:3.40.980.10 196 371 2.7E-56 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 Gene3D G3DSA:3.90.105.10 161 195 4.0E-10 T 28-03-2018 SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 Gene3D G3DSA:3.90.105.10 37 70 3.8E-9 T 28-03-2018 SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 SUPERFAMILY SSF53218 209 369 6.02E-38 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 Pfam PF00994 Probable molybdopterin binding domain 214 363 1.1E-24 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 Gene3D G3DSA:2.40.340.10 377 449 4.2E-24 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 SMART SM00852 213 364 3.8E-39 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 SUPERFAMILY SSF63867 378 448 1.96E-16 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 SUPERFAMILY SSF63882 16 209 1.05E-49 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 210 360 3.0E-32 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 Gene3D G3DSA:2.170.190.11 71 160 1.6E-30 T 28-03-2018 SMD44_RS17300 24e20064c7db3e6607112c1208f15305 449 Pfam PF03454 MoeA C-terminal region (domain IV) 381 448 3.2E-19 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 SUPERFAMILY SSF55781 235 395 6.76E-17 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 Gene3D G3DSA:3.30.450.40 213 395 1.7E-20 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 Gene3D G3DSA:3.30.450.40 10 212 1.0E-21 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 Pfam PF13185 GAF domain 235 382 5.3E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 Pfam PF13185 GAF domain 150 201 2.3E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 SMART SM00065 25 211 3.6E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 SMART SM00065 232 392 2.6E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 Pfam PF07730 Histidine kinase 400 463 2.7E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS13005 27cd6a57bad8f196bf630b387335efca 571 SUPERFAMILY SSF55781 156 225 3.93E-12 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS28045 247ad503a98da7855a62fef3f7abdd2e 516 SUPERFAMILY SSF53474 196 486 2.75E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28045 247ad503a98da7855a62fef3f7abdd2e 516 SUPERFAMILY SSF53474 96 153 2.75E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28045 247ad503a98da7855a62fef3f7abdd2e 516 Gene3D G3DSA:3.40.50.1820 83 505 1.8E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS28045 247ad503a98da7855a62fef3f7abdd2e 516 Pfam PF08386 TAP-like protein 411 515 1.5E-31 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD44_RS08985 15db74274948ed6835085c2ec838d8e4 421 Gene3D G3DSA:3.40.50.2000 143 362 3.0E-40 T 28-03-2018 SMD44_RS08985 15db74274948ed6835085c2ec838d8e4 421 Pfam PF13439 Glycosyltransferase Family 4 13 191 2.8E-8 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS08985 15db74274948ed6835085c2ec838d8e4 421 SUPERFAMILY SSF53756 4 375 1.69E-66 T 28-03-2018 SMD44_RS08985 15db74274948ed6835085c2ec838d8e4 421 Pfam PF00534 Glycosyl transferases group 1 201 355 5.6E-36 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS18535 ea2ee1fbe79f246cc8dc84e4e7eeb311 481 Pfam PF00860 Permease family 40 437 2.5E-26 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS42880 63082d33471891e758dd21a459c8ff70 470 Gene3D G3DSA:1.25.40.10 175 454 1.2E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS42880 63082d33471891e758dd21a459c8ff70 470 SMART SM00028 402 435 11.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS42880 63082d33471891e758dd21a459c8ff70 470 SMART SM00028 363 396 2.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS42880 63082d33471891e758dd21a459c8ff70 470 SUPERFAMILY SSF48452 368 435 2.11E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS43230 2cce9423d73fe6067fb5afe60dccbd39 390 Pfam PF09511 RNA ligase 54 250 6.4E-12 T 28-03-2018 IPR019039 RNA ligase T4 Rnl1, N-terminal SMD44_RS28570 2b14c5615ee16c9b864cd2a93213ac3d 220 SUPERFAMILY SSF46689 32 108 2.19E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS28570 2b14c5615ee16c9b864cd2a93213ac3d 220 SUPERFAMILY SSF48498 111 218 1.37E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS28570 2b14c5615ee16c9b864cd2a93213ac3d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 58 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28570 2b14c5615ee16c9b864cd2a93213ac3d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28570 2b14c5615ee16c9b864cd2a93213ac3d 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 90 2.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28570 2b14c5615ee16c9b864cd2a93213ac3d 220 Gene3D G3DSA:1.10.10.60 27 66 1.6E-16 T 28-03-2018 SMD44_RS28570 2b14c5615ee16c9b864cd2a93213ac3d 220 Gene3D G3DSA:1.10.357.10 94 218 2.9E-13 T 28-03-2018 SMD44_RS28570 2b14c5615ee16c9b864cd2a93213ac3d 220 Gene3D G3DSA:1.10.260.40 67 93 1.3E-12 T 28-03-2018 SMD44_RS11110 71c6a3e1424a919614db2b36a8e57c67 290 Pfam PF00005 ABC transporter 27 186 1.3E-7 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS11110 71c6a3e1424a919614db2b36a8e57c67 290 SUPERFAMILY SSF52540 11 219 4.3E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11110 71c6a3e1424a919614db2b36a8e57c67 290 Gene3D G3DSA:3.40.50.300 3 224 1.9E-23 T 28-03-2018 SMD44_RS10105 9efd909f6bf0d129c52dbe9129302e67 111 Pfam PF13397 RNA polymerase-binding protein 5 108 5.7E-43 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMD44_RS10105 9efd909f6bf0d129c52dbe9129302e67 111 ProSitePatterns PS00202 Rubredoxin signature. 51 61 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 SMD44_RS10105 9efd909f6bf0d129c52dbe9129302e67 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 110 23.84 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMD44_RS32535 e7995247ea83f881d9fe403049b1155a 268 Gene3D G3DSA:3.40.50.1820 7 258 5.9E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS32535 e7995247ea83f881d9fe403049b1155a 268 SUPERFAMILY SSF53474 10 253 7.58E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS32535 e7995247ea83f881d9fe403049b1155a 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS32535 e7995247ea83f881d9fe403049b1155a 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 197 211 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS32535 e7995247ea83f881d9fe403049b1155a 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS32535 e7995247ea83f881d9fe403049b1155a 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS32535 e7995247ea83f881d9fe403049b1155a 268 Pfam PF00561 alpha/beta hydrolase fold 18 240 1.7E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS24230 b1307f73f1167e1e6e17eb426019d32c 242 Pfam PF13649 Methyltransferase domain 37 130 3.9E-18 T 28-03-2018 SMD44_RS24230 b1307f73f1167e1e6e17eb426019d32c 242 SUPERFAMILY SSF53335 18 205 3.31E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS24230 b1307f73f1167e1e6e17eb426019d32c 242 Gene3D G3DSA:3.40.50.150 11 218 1.4E-29 T 28-03-2018 SMD44_RS40475 22b1c3dcf37d239c1ed0f065e097229f 150 Gene3D G3DSA:3.90.79.10 1 149 4.7E-22 T 28-03-2018 SMD44_RS40475 22b1c3dcf37d239c1ed0f065e097229f 150 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS40475 22b1c3dcf37d239c1ed0f065e097229f 150 PRINTS PR00502 NUDIX hydrolase family signature 48 63 3.4E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS40475 22b1c3dcf37d239c1ed0f065e097229f 150 PRINTS PR00502 NUDIX hydrolase family signature 34 48 3.4E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS40475 22b1c3dcf37d239c1ed0f065e097229f 150 SUPERFAMILY SSF55811 10 136 9.34E-23 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS40475 22b1c3dcf37d239c1ed0f065e097229f 150 Pfam PF00293 NUDIX domain 9 122 3.0E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS38060 382701a9528542ee690dbcc17cd78981 528 Pfam PF07969 Amidohydrolase family 261 492 4.6E-34 T 28-03-2018 IPR013108 Amidohydrolase 3 SMD44_RS38060 382701a9528542ee690dbcc17cd78981 528 SUPERFAMILY SSF51556 277 493 1.08E-21 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS38060 382701a9528542ee690dbcc17cd78981 528 Gene3D G3DSA:3.20.20.140 151 491 6.0E-22 T 28-03-2018 SMD44_RS11395 bab30859f4d8485aa61994cf3595b9ba 415 Pfam PF03734 L,D-transpeptidase catalytic domain 248 363 4.2E-14 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD44_RS11395 bab30859f4d8485aa61994cf3595b9ba 415 SUPERFAMILY SSF141523 241 363 1.24E-27 T 28-03-2018 SMD44_RS11395 bab30859f4d8485aa61994cf3595b9ba 415 Gene3D G3DSA:2.60.40.1580 52 167 3.6E-4 T 28-03-2018 SMD44_RS11395 bab30859f4d8485aa61994cf3595b9ba 415 Gene3D G3DSA:2.40.440.10 236 365 9.9E-23 T 28-03-2018 SMD44_RS18700 0aa1c9297cb23cfe23f769eb8059a0cc 358 Gene3D G3DSA:3.40.630.30 238 358 3.8E-15 T 28-03-2018 SMD44_RS18700 0aa1c9297cb23cfe23f769eb8059a0cc 358 SUPERFAMILY SSF55729 232 347 5.23E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS18700 0aa1c9297cb23cfe23f769eb8059a0cc 358 Pfam PF13302 Acetyltransferase (GNAT) domain 241 341 4.9E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS18700 0aa1c9297cb23cfe23f769eb8059a0cc 358 Gene3D G3DSA:1.20.120.450 1 145 7.2E-6 T 28-03-2018 SMD44_RS32810 14c0b77f306a4cd521df8ccccf123c58 271 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS32810 14c0b77f306a4cd521df8ccccf123c58 271 SMART SM00382 56 229 6.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS32810 14c0b77f306a4cd521df8ccccf123c58 271 SUPERFAMILY SSF52540 30 246 1.82E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32810 14c0b77f306a4cd521df8ccccf123c58 271 Pfam PF00005 ABC transporter 47 179 9.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS32810 14c0b77f306a4cd521df8ccccf123c58 271 Gene3D G3DSA:3.40.50.300 24 264 1.0E-57 T 28-03-2018 SMD44_RS31900 3413ab6ca5cc00ce943297c64beddff5 136 PIRSF PIRSF006910 1 133 1.1E-54 T 28-03-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted SMD44_RS31900 3413ab6ca5cc00ce943297c64beddff5 136 Gene3D G3DSA:2.40.50.140 44 132 8.1E-9 T 28-03-2018 SMD44_RS34210 094dd75c99dd5e267bb6e0759a93d045 197 SUPERFAMILY SSF48371 42 189 1.87E-9 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS34210 094dd75c99dd5e267bb6e0759a93d045 197 Gene3D G3DSA:1.25.40.70 2 94 1.2E-4 T 28-03-2018 SMD44_RS34210 094dd75c99dd5e267bb6e0759a93d045 197 Gene3D G3DSA:1.25.40.70 95 191 7.6E-5 T 28-03-2018 SMD44_RS34210 094dd75c99dd5e267bb6e0759a93d045 197 SMART SM00567 E-Z type HEAT repeats 79 108 230.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS34210 094dd75c99dd5e267bb6e0759a93d045 197 SMART SM00567 E-Z type HEAT repeats 148 177 8.1 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS34210 094dd75c99dd5e267bb6e0759a93d045 197 SMART SM00567 E-Z type HEAT repeats 48 77 52.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD44_RS39955 16f01f6b3ad489022192fc68229e4d36 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 182 7.3E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS39955 16f01f6b3ad489022192fc68229e4d36 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 64 3.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS39955 16f01f6b3ad489022192fc68229e4d36 190 Gene3D G3DSA:1.10.10.60 1 62 1.3E-12 T 28-03-2018 SMD44_RS39955 16f01f6b3ad489022192fc68229e4d36 190 Gene3D G3DSA:1.10.357.10 63 190 3.9E-11 T 28-03-2018 SMD44_RS39955 16f01f6b3ad489022192fc68229e4d36 190 SUPERFAMILY SSF48498 79 185 1.82E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS39955 16f01f6b3ad489022192fc68229e4d36 190 SUPERFAMILY SSF46689 11 71 1.9E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 Pfam PF01494 FAD binding domain 6 338 5.3E-65 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 3.2E-37 T 28-03-2018 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.2E-37 T 28-03-2018 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 3.2E-37 T 28-03-2018 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 3.2E-37 T 28-03-2018 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 3.2E-37 T 28-03-2018 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 326 3.2E-37 T 28-03-2018 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 Gene3D G3DSA:3.50.50.60 1 386 4.8E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 SUPERFAMILY SSF51905 262 358 7.07E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS19870 81854fc62cf2620d507f2815803a9c8f 514 SUPERFAMILY SSF51905 6 175 7.07E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS24830 4ec526ab665d66240a2c5828919f55c4 686 Gene3D G3DSA:1.20.5.1230 459 649 3.6E-5 T 28-03-2018 SMD44_RS24830 4ec526ab665d66240a2c5828919f55c4 686 Gene3D G3DSA:1.20.5.1230 16 458 5.4E-6 T 28-03-2018 SMD44_RS06335 aa80c3d6ae9f4029a959116b26951ea5 264 SUPERFAMILY SSF53335 10 216 9.3E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS06335 aa80c3d6ae9f4029a959116b26951ea5 264 Gene3D G3DSA:3.40.50.150 1 254 2.8E-37 T 28-03-2018 SMD44_RS09735 d43868adba914a96036f18185b6e0d9a 127 Gene3D G3DSA:1.10.10.10 31 127 4.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09735 d43868adba914a96036f18185b6e0d9a 127 SUPERFAMILY SSF46785 19 122 4.08E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09735 d43868adba914a96036f18185b6e0d9a 127 Pfam PF01638 HxlR-like helix-turn-helix 34 120 3.3E-25 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS18695 4a24df6185f066b392eb22b919118d45 219 SUPERFAMILY SSF109604 36 215 8.07E-29 T 28-03-2018 SMD44_RS18695 4a24df6185f066b392eb22b919118d45 219 Gene3D G3DSA:1.10.472.50 36 126 3.5E-14 T 28-03-2018 SMD44_RS18695 4a24df6185f066b392eb22b919118d45 219 PIRSF PIRSF035170 2 219 1.8E-73 T 28-03-2018 IPR009218 Predicted HD phosphohydrolase SMD44_RS04525 197d9052ca61d80d047a8bfd0e4bb949 138 SUPERFAMILY SSF55811 10 126 9.75E-32 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS04525 197d9052ca61d80d047a8bfd0e4bb949 138 Gene3D G3DSA:3.90.79.10 2 136 2.0E-28 T 28-03-2018 SMD44_RS04525 197d9052ca61d80d047a8bfd0e4bb949 138 PRINTS PR00502 NUDIX hydrolase family signature 50 65 2.2E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS04525 197d9052ca61d80d047a8bfd0e4bb949 138 PRINTS PR00502 NUDIX hydrolase family signature 36 50 2.2E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS04525 197d9052ca61d80d047a8bfd0e4bb949 138 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS04525 197d9052ca61d80d047a8bfd0e4bb949 138 Pfam PF00293 NUDIX domain 11 114 4.4E-24 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS02940 f822fabea05f602097409c5f26061bea 404 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 56 2.1E-8 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS02940 f822fabea05f602097409c5f26061bea 404 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 223 382 2.0E-8 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 SMD44_RS02940 f822fabea05f602097409c5f26061bea 404 SUPERFAMILY SSF53756 2 400 4.4E-81 T 28-03-2018 SMD44_RS02940 f822fabea05f602097409c5f26061bea 404 Gene3D G3DSA:3.40.50.2000 244 388 6.2E-31 T 28-03-2018 SMD44_RS02940 f822fabea05f602097409c5f26061bea 404 Gene3D G3DSA:3.40.50.2000 2 243 6.0E-41 T 28-03-2018 SMD44_RS14985 7bb06978025bbc60edc34e0513829027 202 SMART SM01006 17 64 4.2E-12 T 28-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain SMD44_RS14985 7bb06978025bbc60edc34e0513829027 202 Pfam PF13523 Acetyltransferase (GNAT) domain 21 163 1.3E-48 T 28-03-2018 SMD44_RS14985 7bb06978025bbc60edc34e0513829027 202 Gene3D G3DSA:3.40.630.30 5 181 1.5E-19 T 28-03-2018 SMD44_RS14985 7bb06978025bbc60edc34e0513829027 202 SUPERFAMILY SSF55729 3 177 1.09E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS11955 fa9c3d185469fb51421a3d07fa063869 340 SUPERFAMILY SSF56219 124 339 8.11E-27 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS11955 fa9c3d185469fb51421a3d07fa063869 340 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 129 331 4.3E-13 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS11955 fa9c3d185469fb51421a3d07fa063869 340 Gene3D G3DSA:3.60.10.10 125 340 1.3E-22 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS34790 675f9ba1a2b7bb749577e4235b5b9565 480 Pfam PF07690 Major Facilitator Superfamily 292 472 9.7E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS34790 675f9ba1a2b7bb749577e4235b5b9565 480 Gene3D G3DSA:1.20.1250.20 276 472 4.9E-24 T 28-03-2018 SMD44_RS34790 675f9ba1a2b7bb749577e4235b5b9565 480 SUPERFAMILY SSF103473 47 459 1.57E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS34790 675f9ba1a2b7bb749577e4235b5b9565 480 Gene3D G3DSA:1.20.1250.20 48 247 9.5E-19 T 28-03-2018 SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 Gene3D G3DSA:2.60.120.10 1 143 2.3E-36 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 4.7E-6 T 28-03-2018 SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 4.7E-6 T 28-03-2018 SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 4.7E-6 T 28-03-2018 SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 4.7E-6 T 28-03-2018 SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 SMART SM00100 10 128 4.0E-27 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 Gene3D G3DSA:1.10.10.10 144 224 6.7E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 4.0E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 SMART SM00419 167 215 2.1E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 SUPERFAMILY SSF51206 3 142 1.57E-39 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 78 95 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 SUPERFAMILY SSF46785 145 222 2.93E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23185 852867701b4a91fd6008c7dc6bb7fc28 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 110 1.0E-25 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS32300 8f0d0098f46eeb3061d1ff11c439b3e2 266 Pfam PF00005 ABC transporter 25 175 1.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS32300 8f0d0098f46eeb3061d1ff11c439b3e2 266 SUPERFAMILY SSF52540 8 225 1.98E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32300 8f0d0098f46eeb3061d1ff11c439b3e2 266 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS32300 8f0d0098f46eeb3061d1ff11c439b3e2 266 Gene3D G3DSA:3.40.50.300 6 266 2.0E-57 T 28-03-2018 SMD44_RS32300 8f0d0098f46eeb3061d1ff11c439b3e2 266 SMART SM00382 34 223 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 Gene3D G3DSA:3.30.70.270 337 557 1.1E-73 T 28-03-2018 SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 SUPERFAMILY SSF55073 428 553 2.35E-36 T 28-03-2018 IPR029787 Nucleotide cyclase SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 SUPERFAMILY SSF55785 201 321 2.74E-19 T 28-03-2018 IPR000014 PAS domain SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 SMART SM00086 283 325 2.4E-4 T 28-03-2018 IPR001610 PAC motif SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 SMART SM00091 213 283 1.8E-6 T 28-03-2018 IPR000014 PAS domain SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 209 331 3.7E-16 T 28-03-2018 IPR000014 PAS domain SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 Gene3D G3DSA:3.30.450.20 191 336 1.9E-30 T 28-03-2018 SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 427 551 4.4E-29 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 Pfam PF00990 Diguanylate cyclase, GGDEF domain 428 551 2.0E-31 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 Pfam PF00989 PAS fold 234 312 2.9E-8 T 28-03-2018 IPR013767 PAS fold GO:0006355 SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 SUPERFAMILY SSF55781 12 192 3.49E-16 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 SMART SM00267 325 557 8.1E-28 T 28-03-2018 IPR000160 GGDEF domain SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 SMART SM00065 29 195 0.0016 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS18855 9ec78b173bcfddb84c669a6acc6aa0d7 558 Gene3D G3DSA:3.30.450.40 9 190 3.1E-27 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 208 1.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 SMART SM00448 1 114 2.4E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 Gene3D G3DSA:3.40.50.2300 1 124 1.9E-39 T 28-03-2018 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 Gene3D G3DSA:1.10.10.10 125 214 1.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 SMART SM00421 151 208 3.7E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 SUPERFAMILY SSF52172 2 130 1.12E-36 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 Pfam PF00072 Response regulator receiver domain 3 114 1.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS04150 6a955b0e072e9a88a710d7e1bdc8f715 214 SUPERFAMILY SSF46894 152 214 2.28E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS38160 b6bc4c65a1e0cad512df4d5786b19abc 191 SUPERFAMILY SSF48498 78 181 4.23E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS38160 b6bc4c65a1e0cad512df4d5786b19abc 191 Gene3D G3DSA:1.10.10.60 2 69 9.3E-10 T 28-03-2018 SMD44_RS38160 b6bc4c65a1e0cad512df4d5786b19abc 191 SUPERFAMILY SSF46689 6 68 1.15E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS38160 b6bc4c65a1e0cad512df4d5786b19abc 191 Gene3D G3DSA:1.10.357.10 72 191 2.5E-23 T 28-03-2018 SMD44_RS38160 b6bc4c65a1e0cad512df4d5786b19abc 191 Pfam PF13305 WHG domain 84 160 6.3E-7 T 28-03-2018 IPR025996 WHG domain SMD44_RS38160 b6bc4c65a1e0cad512df4d5786b19abc 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 3.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS38065 9b1519edf11ea3c4a34d4df4be64460b 407 Gene3D G3DSA:2.120.10.30 203 352 3.8E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS38065 9b1519edf11ea3c4a34d4df4be64460b 407 Gene3D G3DSA:2.120.10.30 55 202 2.4E-15 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS38065 9b1519edf11ea3c4a34d4df4be64460b 407 SUPERFAMILY SSF63829 56 333 1.8E-28 T 28-03-2018 SMD44_RS17470 243e5b62b3f66563ff63de82748343cd 418 Gene3D G3DSA:3.30.9.10 193 342 4.3E-43 T 28-03-2018 SMD44_RS17470 243e5b62b3f66563ff63de82748343cd 418 SUPERFAMILY SSF54373 251 343 7.06E-7 T 28-03-2018 SMD44_RS17470 243e5b62b3f66563ff63de82748343cd 418 Pfam PF01266 FAD dependent oxidoreductase 36 381 5.0E-68 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS17470 243e5b62b3f66563ff63de82748343cd 418 Gene3D G3DSA:3.50.50.60 2 92 2.6E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17470 243e5b62b3f66563ff63de82748343cd 418 Gene3D G3DSA:3.30.9.10 115 192 3.8E-14 T 28-03-2018 SMD44_RS17470 243e5b62b3f66563ff63de82748343cd 418 SUPERFAMILY SSF51905 35 251 1.17E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS17470 243e5b62b3f66563ff63de82748343cd 418 SUPERFAMILY SSF51905 343 401 1.17E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32780 ec9f5675b6026cea9b4f7cdf542bbb7e 127 SUPERFAMILY SSF54427 12 118 7.8E-14 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS32780 ec9f5675b6026cea9b4f7cdf542bbb7e 127 Pfam PF14534 Domain of unknown function (DUF4440) 14 110 3.1E-12 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 SMD44_RS32780 ec9f5675b6026cea9b4f7cdf542bbb7e 127 Gene3D G3DSA:3.10.450.50 7 118 7.2E-24 T 28-03-2018 SMD44_RS09560 a4e8754d190b44a14558d0bf63a98d7f 137 Gene3D G3DSA:3.10.180.10 8 136 1.5E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS09560 a4e8754d190b44a14558d0bf63a98d7f 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 128 5.3E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS09560 a4e8754d190b44a14558d0bf63a98d7f 137 SUPERFAMILY SSF54593 14 134 2.82E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS38280 280153307c92de404037cde165629526 307 SUPERFAMILY SSF53850 34 306 1.44E-42 T 28-03-2018 SMD44_RS38280 280153307c92de404037cde165629526 307 Gene3D G3DSA:3.40.190.120 156 246 7.5E-25 T 28-03-2018 SMD44_RS38280 280153307c92de404037cde165629526 307 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 33 302 1.9E-50 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD44_RS38280 280153307c92de404037cde165629526 307 Gene3D G3DSA:3.40.190.10 18 155 6.9E-20 T 28-03-2018 SMD44_RS17750 f3a1f183b29b7da9acc2e50e0023f04e 432 Pfam PF07690 Major Facilitator Superfamily 25 248 1.8E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS17750 f3a1f183b29b7da9acc2e50e0023f04e 432 SUPERFAMILY SSF103473 23 409 9.94E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17750 f3a1f183b29b7da9acc2e50e0023f04e 432 Gene3D G3DSA:1.20.1250.20 6 204 2.1E-15 T 28-03-2018 SMD44_RS17750 f3a1f183b29b7da9acc2e50e0023f04e 432 Gene3D G3DSA:1.20.1250.20 230 419 1.7E-13 T 28-03-2018 SMD44_RS42845 61bb28a9b138f6fbd6994e96e2eba544 217 SUPERFAMILY SSF52540 21 205 7.11E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS42845 61bb28a9b138f6fbd6994e96e2eba544 217 Gene3D G3DSA:3.40.50.300 16 208 2.9E-21 T 28-03-2018 SMD44_RS42845 61bb28a9b138f6fbd6994e96e2eba544 217 Pfam PF03029 Conserved hypothetical ATP binding protein 30 200 3.3E-17 T 28-03-2018 IPR004130 GPN-loop GTPase SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 175 0.001 T 28-03-2018 SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 8.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 8.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 8.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 240 8.4E-54 T 28-03-2018 SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 SUPERFAMILY SSF51735 4 240 3.31E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 6.1E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 6.1E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 6.1E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 6.1E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.1E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 6.1E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 Gene3D G3DSA:3.40.50.720 45 246 4.0E-52 T 28-03-2018 SMD44_RS35155 6b365bd2e31a2d83b0629d733099c174 254 Gene3D G3DSA:3.40.50.720 1 44 1.2E-8 T 28-03-2018 SMD44_RS09015 24522686b622e23aa5d5a2410f5e3a18 184 SMART SM00257 133 182 8.4E-9 T 28-03-2018 IPR018392 LysM domain SMD44_RS09015 24522686b622e23aa5d5a2410f5e3a18 184 Pfam PF06737 Transglycosylase-like domain 42 113 2.9E-30 T 28-03-2018 IPR010618 Transglycosylase-like SMD44_RS09015 24522686b622e23aa5d5a2410f5e3a18 184 SUPERFAMILY SSF53955 41 116 1.1E-29 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS09015 24522686b622e23aa5d5a2410f5e3a18 184 SUPERFAMILY SSF54106 132 182 2.22E-7 T 28-03-2018 IPR018392 LysM domain SMD44_RS09015 24522686b622e23aa5d5a2410f5e3a18 184 Gene3D G3DSA:3.10.350.10 131 184 1.8E-14 T 28-03-2018 SMD44_RS09015 24522686b622e23aa5d5a2410f5e3a18 184 Gene3D G3DSA:1.10.530.10 20 120 1.6E-30 T 28-03-2018 SMD44_RS09015 24522686b622e23aa5d5a2410f5e3a18 184 Pfam PF01476 LysM domain 134 182 4.0E-9 T 28-03-2018 IPR018392 LysM domain SMD44_RS32525 32ba144115aa14a2068893fc31c48b0a 422 Pfam PF06889 Protein of unknown function (DUF1266) 211 421 1.2E-42 T 28-03-2018 IPR009677 Protein of unknown function DUF1266 SMD44_RS22110 6c189c6a4bae9a41f4b58eee148964b7 342 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 136 323 9.7E-13 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS22110 6c189c6a4bae9a41f4b58eee148964b7 342 Gene3D G3DSA:3.60.10.10 117 341 7.1E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS22110 6c189c6a4bae9a41f4b58eee148964b7 342 SUPERFAMILY SSF56219 118 332 4.06E-26 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 Pfam PF00069 Protein kinase domain 269 431 8.5E-8 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 SMART SM01260 523 833 4.8E-4 T 28-03-2018 IPR007822 Lanthionine synthetase C-like SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 SUPERFAMILY SSF158745 517 783 1.57E-22 T 28-03-2018 SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 Gene3D G3DSA:1.20.1250.20 886 1067 9.1E-19 T 28-03-2018 SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 Pfam PF07690 Major Facilitator Superfamily 889 1064 1.1E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 Gene3D G3DSA:1.10.510.10 268 471 2.1E-14 T 28-03-2018 SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 SUPERFAMILY SSF103473 889 1063 2.88E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 Gene3D G3DSA:1.50.10.20 472 816 3.3E-7 T 28-03-2018 SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 SMART SM00220 232 522 5.9E-4 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS41455 a0bff0b1c41b2ee9e264e9012b7aaa45 1088 SUPERFAMILY SSF56112 268 444 5.26E-17 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS38535 d632ace090983e4552f98063f0ccc299 154 SUPERFAMILY SSF55961 6 142 6.26E-18 T 28-03-2018 SMD44_RS38535 d632ace090983e4552f98063f0ccc299 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 137 7.8E-16 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS38535 d632ace090983e4552f98063f0ccc299 154 Gene3D G3DSA:3.30.530.20 2 151 1.9E-18 T 28-03-2018 IPR023393 START-like domain SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 Gene3D G3DSA:2.140.10.10 668 827 2.2E-11 T 28-03-2018 SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 Pfam PF13360 PQQ-like domain 688 817 2.0E-8 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 Gene3D G3DSA:2.140.10.10 404 638 3.8E-8 T 28-03-2018 SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 SUPERFAMILY SSF56112 13 273 2.83E-59 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 Gene3D G3DSA:1.10.510.10 97 317 9.7E-41 T 28-03-2018 SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 SUPERFAMILY SSF50998 429 568 1.74E-10 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 SUPERFAMILY SSF50998 691 817 1.74E-10 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 SUPERFAMILY SSF50998 606 664 1.74E-10 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 Pfam PF00069 Protein kinase domain 19 268 1.1E-36 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 Gene3D G3DSA:3.30.200.20 6 96 4.1E-11 T 28-03-2018 SMD44_RS09880 3a44832bc5d30a159487410673081fce 827 SMART SM00220 16 277 1.0E-38 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS14610 e0ba595c39ee2921605b4e03e59215e8 417 Gene3D G3DSA:1.10.443.10 190 404 2.4E-24 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS14610 e0ba595c39ee2921605b4e03e59215e8 417 Gene3D G3DSA:1.10.150.130 78 189 5.0E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS14610 e0ba595c39ee2921605b4e03e59215e8 417 Pfam PF00589 Phage integrase family 215 389 1.4E-8 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS14610 e0ba595c39ee2921605b4e03e59215e8 417 SUPERFAMILY SSF56349 82 396 2.59E-40 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS30490 d923b3abe18de67322dc70e37f88ded1 273 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 238 2.4E-65 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD44_RS30490 d923b3abe18de67322dc70e37f88ded1 273 PIRSF PIRSF000386 1 259 1.9E-95 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD44_RS30490 d923b3abe18de67322dc70e37f88ded1 273 SUPERFAMILY SSF75217 1 246 6.19E-84 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SMD44_RS30490 d923b3abe18de67322dc70e37f88ded1 273 Gene3D G3DSA:1.10.1270.20 179 256 5.1E-28 T 28-03-2018 SMD44_RS30490 d923b3abe18de67322dc70e37f88ded1 273 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 273 99.459 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD44_RS30490 d923b3abe18de67322dc70e37f88ded1 273 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 232 1.2E-71 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD44_RS30490 d923b3abe18de67322dc70e37f88ded1 273 Gene3D G3DSA:3.40.1280.10 1 178 2.9E-66 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD44_RS01310 1f5a0cc494dd60a4abc65d74a23056c3 163 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 47 65 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site SMD44_RS01310 1f5a0cc494dd60a4abc65d74a23056c3 163 Gene3D G3DSA:1.10.10.10 1 147 4.1E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01310 1f5a0cc494dd60a4abc65d74a23056c3 163 Pfam PF02082 Transcriptional regulator 1 81 2.5E-24 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type SMD44_RS01310 1f5a0cc494dd60a4abc65d74a23056c3 163 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 9.6E-30 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type SMD44_RS01310 1f5a0cc494dd60a4abc65d74a23056c3 163 SUPERFAMILY SSF46785 7 136 7.86E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14185 3abd67f437dfa0a5f0b1b5759bb2a26a 147 SUPERFAMILY SSF109604 5 145 2.7E-22 T 28-03-2018 SMD44_RS14185 3abd67f437dfa0a5f0b1b5759bb2a26a 147 Pfam PF13328 HD domain 12 68 2.3E-7 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS15015 1f61a9b7a8965cc599da67003ae7fb11 174 PRINTS PR01438 Universal stress protein signature 38 56 2.6E-6 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS15015 1f61a9b7a8965cc599da67003ae7fb11 174 PRINTS PR01438 Universal stress protein signature 152 174 2.6E-6 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS15015 1f61a9b7a8965cc599da67003ae7fb11 174 Pfam PF00582 Universal stress protein family 41 174 3.5E-23 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS15015 1f61a9b7a8965cc599da67003ae7fb11 174 SUPERFAMILY SSF52402 41 174 7.12E-22 T 28-03-2018 SMD44_RS15015 1f61a9b7a8965cc599da67003ae7fb11 174 Gene3D G3DSA:3.40.50.620 15 173 7.4E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS31470 ea647d99db6c1634907f7916810d69f8 308 Pfam PF03747 ADP-ribosylglycohydrolase 17 281 4.4E-46 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS31470 ea647d99db6c1634907f7916810d69f8 308 SUPERFAMILY SSF101478 10 303 2.75E-52 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS31470 ea647d99db6c1634907f7916810d69f8 308 Gene3D G3DSA:1.10.4080.10 8 302 2.1E-63 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS01325 185c6d213dd18f16494ab8e0e6bdd631 193 PIRSF PIRSF016573 4 188 2.3E-33 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS01325 185c6d213dd18f16494ab8e0e6bdd631 193 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 162 176 2.2E-16 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS01325 185c6d213dd18f16494ab8e0e6bdd631 193 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 48 74 2.2E-16 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS01325 185c6d213dd18f16494ab8e0e6bdd631 193 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 135 159 2.2E-16 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS01325 185c6d213dd18f16494ab8e0e6bdd631 193 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 49 170 1.0E-27 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS01325 185c6d213dd18f16494ab8e0e6bdd631 193 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 42 177 1.9E-27 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD44_RS01325 185c6d213dd18f16494ab8e0e6bdd631 193 SUPERFAMILY SSF55486 43 175 5.06E-22 T 28-03-2018 SMD44_RS01325 185c6d213dd18f16494ab8e0e6bdd631 193 Gene3D G3DSA:3.40.390.10 41 177 1.9E-19 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD44_RS41020 3f8b9a546ef91bfd46e6c546795d6f8f 343 Gene3D G3DSA:3.30.1370.60 180 341 1.6E-47 T 28-03-2018 SMD44_RS41020 3f8b9a546ef91bfd46e6c546795d6f8f 343 SUPERFAMILY SSF89733 174 339 9.42E-44 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 SMD44_RS41020 3f8b9a546ef91bfd46e6c546795d6f8f 343 Pfam PF02615 Malate/L-lactate dehydrogenase 180 339 6.0E-47 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 SMD44_RS36645 6b3696156cc96df8ffb74cb6e9d45ca5 264 Gene3D G3DSA:3.90.1300.10 13 251 4.4E-38 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS36645 6b3696156cc96df8ffb74cb6e9d45ca5 264 Pfam PF01425 Amidase 31 225 1.6E-20 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS36645 6b3696156cc96df8ffb74cb6e9d45ca5 264 SUPERFAMILY SSF75304 27 242 4.19E-38 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS13320 c687ae778522a27775650483669d5452 427 Gene3D G3DSA:1.10.10.10 356 427 1.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13320 c687ae778522a27775650483669d5452 427 SUPERFAMILY SSF88946 126 264 2.75E-51 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 218 231 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 387 413 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 Gene3D G3DSA:1.10.10.10 300 318 0.082 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13320 c687ae778522a27775650483669d5452 427 Pfam PF00140 Sigma-70 factor, region 1.2 129 162 4.5E-15 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 Gene3D G3DSA:1.10.601.10 62 263 2.8E-68 T 28-03-2018 SMD44_RS13320 c687ae778522a27775650483669d5452 427 Pfam PF04545 Sigma-70, region 4 362 415 9.5E-20 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 Gene3D G3DSA:1.10.10.10 264 299 4.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13320 c687ae778522a27775650483669d5452 427 Pfam PF04542 Sigma-70 region 2 194 263 1.9E-23 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 SUPERFAMILY SSF88659 325 423 4.3E-28 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 190 415 2.8E-38 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 Pfam PF04539 Sigma-70 region 3 273 349 5.0E-27 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 PRINTS PR00046 Major sigma-70 factor signature 218 231 9.6E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 PRINTS PR00046 Major sigma-70 factor signature 366 378 9.6E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 PRINTS PR00046 Major sigma-70 factor signature 402 413 9.6E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 PRINTS PR00046 Major sigma-70 factor signature 242 250 9.6E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 PRINTS PR00046 Major sigma-70 factor signature 387 402 9.6E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS13320 c687ae778522a27775650483669d5452 427 SUPERFAMILY SSF88659 267 340 3.4E-19 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS15275 d5479ef8f0274909e6ba86a2328e35f2 743 SUPERFAMILY SSF82866 138 337 1.57E-32 T 28-03-2018 SMD44_RS15275 d5479ef8f0274909e6ba86a2328e35f2 743 Pfam PF03176 MMPL family 69 362 1.3E-52 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS15275 d5479ef8f0274909e6ba86a2328e35f2 743 Pfam PF03176 MMPL family 467 683 4.1E-29 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS15275 d5479ef8f0274909e6ba86a2328e35f2 743 SUPERFAMILY SSF82866 476 680 2.09E-23 T 28-03-2018 SMD44_RS15275 d5479ef8f0274909e6ba86a2328e35f2 743 Gene3D G3DSA:1.20.1640.10 458 679 1.9E-31 T 28-03-2018 SMD44_RS15275 d5479ef8f0274909e6ba86a2328e35f2 743 Gene3D G3DSA:1.20.1640.10 127 346 3.2E-37 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:1.25.40.10 592 674 4.7E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:1.10.10.10 487 504 0.012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:1.25.40.10 561 591 1.6E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:1.25.40.10 433 468 1.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:2.60.40.1180 505 520 0.17 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:2.60.40.1180 469 486 0.14 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Pfam PF13374 Tetratricopeptide repeat 609 635 5.8E-4 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Pfam PF13374 Tetratricopeptide repeat 454 476 0.0048 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Pfam PF13374 Tetratricopeptide repeat 546 571 0.0039 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Pfam PF13374 Tetratricopeptide repeat 422 444 0.0077 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 SUPERFAMILY SSF81901 419 649 1.78E-29 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:3.40.50.880 70 390 0.068 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Pfam PF13432 Tetratricopeptide repeat 486 537 0.0022 T 28-03-2018 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:1.25.40.10 521 560 5.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Pfam PF07721 Tetratricopeptide repeat 579 601 0.0099 T 28-03-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Pfam PF07721 Tetratricopeptide repeat 642 666 0.0098 T 28-03-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 SMD44_RS18430 ad780c7859d8ab4dca371990841a62a7 674 Gene3D G3DSA:1.25.40.10 391 432 0.022 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.9E-9 T 28-03-2018 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.9E-9 T 28-03-2018 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 369 1.9E-9 T 28-03-2018 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 1.9E-9 T 28-03-2018 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 Gene3D G3DSA:3.50.50.60 2 171 1.2E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 SUPERFAMILY SSF51905 4 387 1.01E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 Gene3D G3DSA:3.50.50.60 172 400 2.6E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.8E-7 T 28-03-2018 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 4.8E-7 T 28-03-2018 SMD44_RS25105 818e38b150f1c999b8313c9fc46c4c3b 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 213 2.0E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS26785 bb2cc04ba33ac8fa4d471bf012d9e18d 420 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 345 1.6E-35 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS26785 bb2cc04ba33ac8fa4d471bf012d9e18d 420 Gene3D G3DSA:1.10.3470.10 50 408 6.4E-48 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS20440 2c6e86cded245a9d7c974c28d385c2ed 388 PIRSF PIRSF000429 10 373 1.7E-19 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS20440 2c6e86cded245a9d7c974c28d385c2ed 388 Gene3D G3DSA:3.40.47.10 5 140 4.8E-8 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS20440 2c6e86cded245a9d7c974c28d385c2ed 388 Gene3D G3DSA:3.40.47.10 152 383 5.6E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS20440 2c6e86cded245a9d7c974c28d385c2ed 388 SUPERFAMILY SSF53901 12 237 5.07E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS20440 2c6e86cded245a9d7c974c28d385c2ed 388 SUPERFAMILY SSF53901 266 377 4.08E-12 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01930 d3192b7d431be0cba510e3c09cf146df 596 Pfam PF01144 Coenzyme A transferase 17 246 1.3E-23 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMD44_RS01930 d3192b7d431be0cba510e3c09cf146df 596 SUPERFAMILY SSF100950 348 593 2.51E-25 T 28-03-2018 SMD44_RS01930 d3192b7d431be0cba510e3c09cf146df 596 Gene3D G3DSA:3.40.1080.10 344 596 9.8E-28 T 28-03-2018 SMD44_RS01930 d3192b7d431be0cba510e3c09cf146df 596 Gene3D G3DSA:3.40.1080.10 13 332 2.1E-41 T 28-03-2018 SMD44_RS01930 d3192b7d431be0cba510e3c09cf146df 596 SMART SM00882 14 250 1.7E-6 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMD44_RS01930 d3192b7d431be0cba510e3c09cf146df 596 SUPERFAMILY SSF100950 16 325 1.41E-50 T 28-03-2018 SMD44_RS13040 1d0ef12492614446a7790d5cf06d55bc 342 Gene3D G3DSA:3.40.50.1980 33 170 7.0E-24 T 28-03-2018 SMD44_RS13040 1d0ef12492614446a7790d5cf06d55bc 342 Gene3D G3DSA:3.40.50.1980 171 337 9.4E-34 T 28-03-2018 SMD44_RS13040 1d0ef12492614446a7790d5cf06d55bc 342 SUPERFAMILY SSF53807 41 317 2.2E-40 T 28-03-2018 SMD44_RS13040 1d0ef12492614446a7790d5cf06d55bc 342 Pfam PF01497 Periplasmic binding protein 61 314 3.9E-30 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 Pfam PF00156 Phosphoribosyl transferase domain 306 403 2.7E-6 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 PIRSF PIRSF000485 19 485 2.8E-160 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 473 45.984 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 SUPERFAMILY SSF56235 23 286 6.86E-64 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 Pfam PF13522 Glutamine amidotransferase domain 83 227 4.5E-15 T 28-03-2018 SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 SUPERFAMILY SSF53271 268 482 3.09E-68 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 474 4.7E-156 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 Gene3D G3DSA:3.60.20.10 23 261 9.5E-61 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS19945 f4eda9c0fe70139377b41a4134c85afe 508 Gene3D G3DSA:3.40.50.2020 262 459 1.7E-31 T 28-03-2018 SMD44_RS28715 75dd4fd2f1119911c5eb101e1f1cfbf7 459 Pfam PF01098 Cell cycle protein 82 442 1.9E-70 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SMD44_RS24085 c1007418acaed89a7907163b4734acc5 418 SUPERFAMILY SSF103473 7 396 1.7E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS24085 c1007418acaed89a7907163b4734acc5 418 Gene3D G3DSA:1.20.1250.20 216 407 1.9E-24 T 28-03-2018 SMD44_RS24085 c1007418acaed89a7907163b4734acc5 418 Gene3D G3DSA:1.20.1250.20 4 183 5.9E-10 T 28-03-2018 SMD44_RS24085 c1007418acaed89a7907163b4734acc5 418 Pfam PF07690 Major Facilitator Superfamily 224 398 8.0E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS04250 df0df0b79932bd4659f29b136e07686c 344 Gene3D G3DSA:1.10.150.130 51 151 5.8E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS04250 df0df0b79932bd4659f29b136e07686c 344 SUPERFAMILY SSF56349 54 318 1.38E-38 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS04250 df0df0b79932bd4659f29b136e07686c 344 Gene3D G3DSA:1.10.443.10 154 324 1.5E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS04250 df0df0b79932bd4659f29b136e07686c 344 Pfam PF00589 Phage integrase family 156 317 2.4E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS25560 c80fdbb0bf18ac58d8993bc249685cab 185 SUPERFAMILY SSF55282 8 183 1.27E-74 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25560 c80fdbb0bf18ac58d8993bc249685cab 185 PIRSF PIRSF002161 1 185 4.4E-63 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25560 c80fdbb0bf18ac58d8993bc249685cab 185 Gene3D G3DSA:3.30.1440.10 6 184 2.1E-74 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25560 c80fdbb0bf18ac58d8993bc249685cab 185 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 6 184 43.189 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS25560 c80fdbb0bf18ac58d8993bc249685cab 185 Pfam PF00673 ribosomal L5P family C-terminus 89 182 9.1E-39 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25560 c80fdbb0bf18ac58d8993bc249685cab 185 Pfam PF00281 Ribosomal protein L5 29 85 1.3E-28 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25560 c80fdbb0bf18ac58d8993bc249685cab 185 ProSitePatterns PS00358 Ribosomal protein L5 signature. 62 78 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS29185 60e886e9d790d91520ba3891362b9833 339 Gene3D G3DSA:3.90.25.10 189 337 1.1E-34 T 28-03-2018 SMD44_RS29185 60e886e9d790d91520ba3891362b9833 339 SUPERFAMILY SSF51735 12 331 5.68E-93 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29185 60e886e9d790d91520ba3891362b9833 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 20 319 7.2E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29185 60e886e9d790d91520ba3891362b9833 339 Gene3D G3DSA:3.40.50.720 17 188 6.6E-42 T 28-03-2018 SMD44_RS28105 ff136d9dd9bc42d4df24d236b8ba125e 122 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 27 111 14.703 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS28105 ff136d9dd9bc42d4df24d236b8ba125e 122 Pfam PF02467 Transcription factor WhiB 49 97 9.3E-15 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS28105 ff136d9dd9bc42d4df24d236b8ba125e 122 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 107 117 - T 28-03-2018 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 SMART SM00220 17 177 0.0012 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 Gene3D G3DSA:2.140.10.10 531 753 3.2E-9 T 28-03-2018 SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 Gene3D G3DSA:1.10.510.10 39 210 2.2E-27 T 28-03-2018 SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 SUPERFAMILY SSF50998 624 707 8.77E-19 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 SUPERFAMILY SSF50998 399 587 8.77E-19 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 Pfam PF00069 Protein kinase domain 45 175 5.8E-18 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 Pfam PF13360 PQQ-like domain 409 578 3.5E-15 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 Gene3D G3DSA:2.140.10.10 340 530 9.1E-16 T 28-03-2018 SMD44_RS29470 83ecf20312ce0e03aedd501e849a434b 764 SUPERFAMILY SSF56112 44 177 1.35E-29 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS22325 6a4028f4f02ff2c5130f9bc332688a34 360 Gene3D G3DSA:3.40.50.1820 65 357 2.5E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS22325 6a4028f4f02ff2c5130f9bc332688a34 360 SUPERFAMILY SSF53474 66 356 4.46E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS22325 6a4028f4f02ff2c5130f9bc332688a34 360 PRINTS PR00412 Epoxide hydrolase signature 92 110 6.6E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS22325 6a4028f4f02ff2c5130f9bc332688a34 360 PRINTS PR00412 Epoxide hydrolase signature 174 187 6.6E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS22325 6a4028f4f02ff2c5130f9bc332688a34 360 PRINTS PR00412 Epoxide hydrolase signature 335 357 6.6E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS22325 6a4028f4f02ff2c5130f9bc332688a34 360 PRINTS PR00412 Epoxide hydrolase signature 112 127 6.6E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS22325 6a4028f4f02ff2c5130f9bc332688a34 360 PRINTS PR00412 Epoxide hydrolase signature 160 173 6.6E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS22325 6a4028f4f02ff2c5130f9bc332688a34 360 Pfam PF00561 alpha/beta hydrolase fold 86 215 3.8E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 140 156 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 94 105 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 157 172 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 278 289 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 323 338 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 353 364 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 197 219 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 295 322 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 PRINTS PR00359 B-class P450 signature 344 353 3.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 Pfam PF00067 Cytochrome P450 277 371 6.6E-17 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 Gene3D G3DSA:1.10.630.10 2 404 4.6E-69 T 28-03-2018 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS31860 cfeddf89cd9bf1dd74627a3ca8e69ad0 404 SUPERFAMILY SSF48264 16 404 2.36E-84 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS06390 d77f1f3ca5f7df2f856c3afaaf7a4a39 201 Pfam PF07883 Cupin domain 73 139 2.5E-15 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS06390 d77f1f3ca5f7df2f856c3afaaf7a4a39 201 SUPERFAMILY SSF51182 25 167 4.1E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS06390 d77f1f3ca5f7df2f856c3afaaf7a4a39 201 Gene3D G3DSA:2.60.120.10 28 161 3.1E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS39275 16bbd0556782410f57168770d2c900fc 214 SUPERFAMILY SSF55846 72 212 5.5E-41 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS39275 16bbd0556782410f57168770d2c900fc 214 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 78 199 6.5E-31 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS39275 16bbd0556782410f57168770d2c900fc 214 Gene3D G3DSA:3.40.80.10 39 214 1.5E-40 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS39275 16bbd0556782410f57168770d2c900fc 214 SMART SM00644 69 199 9.7E-47 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS30500 acf7f3e944d3287698a02b2e17379d7a 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 69 85 2.3E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30500 acf7f3e944d3287698a02b2e17379d7a 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 123 135 2.3E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30500 acf7f3e944d3287698a02b2e17379d7a 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 171 190 2.3E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30500 acf7f3e944d3287698a02b2e17379d7a 240 Pfam PF00717 Peptidase S24-like 76 148 1.9E-14 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30500 acf7f3e944d3287698a02b2e17379d7a 240 ProSitePatterns PS00501 Signal peptidases I serine active site. 78 85 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 SMD44_RS30500 acf7f3e944d3287698a02b2e17379d7a 240 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 54 217 3.1E-38 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30500 acf7f3e944d3287698a02b2e17379d7a 240 Gene3D G3DSA:2.10.109.10 65 232 7.8E-43 T 28-03-2018 SMD44_RS30500 acf7f3e944d3287698a02b2e17379d7a 240 SUPERFAMILY SSF51306 68 223 4.53E-45 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS43700 6f5a63ca8ddf2f85f708deb8278b90a8 482 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 35 151 2.5E-6 T 28-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 SMD44_RS43700 6f5a63ca8ddf2f85f708deb8278b90a8 482 Pfam PF12696 TraM recognition site of TraD and TraG 291 411 1.0E-23 T 28-03-2018 IPR032689 TraD/TraG, TraM recognition site SMD44_RS43700 6f5a63ca8ddf2f85f708deb8278b90a8 482 Gene3D G3DSA:3.40.50.300 33 437 8.0E-20 T 28-03-2018 SMD44_RS43700 6f5a63ca8ddf2f85f708deb8278b90a8 482 SUPERFAMILY SSF52540 12 429 1.13E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS41585 3c0b78c06f055ba05c0b952c9ec0ea36 208 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 11 159 1.4E-37 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 SMD44_RS41585 3c0b78c06f055ba05c0b952c9ec0ea36 208 SUPERFAMILY SSF89155 3 164 1.57E-30 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMD44_RS41585 3c0b78c06f055ba05c0b952c9ec0ea36 208 Gene3D G3DSA:1.10.3480.10 1 181 3.4E-28 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMD44_RS41585 3c0b78c06f055ba05c0b952c9ec0ea36 208 Pfam PF02613 Nitrate reductase delta subunit 39 155 1.2E-11 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMD44_RS16150 4dcc0f66a091f6805e7407f853535b7b 286 SMART SM00382 72 277 1.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16150 4dcc0f66a091f6805e7407f853535b7b 286 Pfam PF00005 ABC transporter 64 210 4.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS16150 4dcc0f66a091f6805e7407f853535b7b 286 SUPERFAMILY SSF52540 47 263 6.05E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16150 4dcc0f66a091f6805e7407f853535b7b 286 Gene3D G3DSA:3.40.50.300 44 270 3.6E-63 T 28-03-2018 SMD44_RS16150 4dcc0f66a091f6805e7407f853535b7b 286 ProSitePatterns PS00211 ABC transporters family signature. 183 197 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS01300 85092bd7c48b301cf1c205117f367215 502 Pfam PF00561 alpha/beta hydrolase fold 111 296 5.1E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS01300 85092bd7c48b301cf1c205117f367215 502 SUPERFAMILY SSF53474 345 495 2.83E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01300 85092bd7c48b301cf1c205117f367215 502 SUPERFAMILY SSF53474 205 259 2.83E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01300 85092bd7c48b301cf1c205117f367215 502 SUPERFAMILY SSF53474 131 164 2.83E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01300 85092bd7c48b301cf1c205117f367215 502 Gene3D G3DSA:3.40.50.1820 81 498 4.3E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01300 85092bd7c48b301cf1c205117f367215 502 Pfam PF08386 TAP-like protein 411 497 5.1E-13 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD44_RS03350 332c17cfc5a7ca62d3960b5dded22499 220 SUPERFAMILY SSF160904 17 215 3.66E-33 T 28-03-2018 SMD44_RS03350 332c17cfc5a7ca62d3960b5dded22499 220 Gene3D G3DSA:1.10.3300.10 14 218 6.1E-42 T 28-03-2018 IPR023286 ABATE domain SMD44_RS03350 332c17cfc5a7ca62d3960b5dded22499 220 Pfam PF11706 CGNR zinc finger 176 215 6.3E-10 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS03350 332c17cfc5a7ca62d3960b5dded22499 220 Pfam PF07336 Putative stress-induced transcription regulator 23 172 9.3E-15 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS11870 fd4d7f25195db64f38a847891cbb2ad9 453 SMART SM01230 104 363 6.9E-123 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11870 fd4d7f25195db64f38a847891cbb2ad9 453 Gene3D G3DSA:3.30.590.10 104 453 4.5E-113 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD44_RS11870 fd4d7f25195db64f38a847891cbb2ad9 453 SUPERFAMILY SSF55931 106 450 2.45E-113 T 28-03-2018 SMD44_RS11870 fd4d7f25195db64f38a847891cbb2ad9 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 3.2E-28 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11870 fd4d7f25195db64f38a847891cbb2ad9 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMD44_RS11870 fd4d7f25195db64f38a847891cbb2ad9 453 Gene3D G3DSA:3.10.20.70 1 103 1.4E-33 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11870 fd4d7f25195db64f38a847891cbb2ad9 453 Pfam PF00120 Glutamine synthetase, catalytic domain 105 448 9.1E-127 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS11870 fd4d7f25195db64f38a847891cbb2ad9 453 SUPERFAMILY SSF54368 8 103 3.92E-30 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD44_RS07920 d70cdf92faafd7fcccf81a69dbb9db5f 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.765 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD44_RS07920 d70cdf92faafd7fcccf81a69dbb9db5f 64 Pfam PF01632 Ribosomal protein L35 2 62 4.7E-24 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS07920 d70cdf92faafd7fcccf81a69dbb9db5f 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 8.1E-17 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD44_RS07920 d70cdf92faafd7fcccf81a69dbb9db5f 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 8.1E-17 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD44_RS07920 d70cdf92faafd7fcccf81a69dbb9db5f 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 8.1E-17 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD44_RS07920 d70cdf92faafd7fcccf81a69dbb9db5f 64 SUPERFAMILY SSF143034 2 63 6.41E-22 T 28-03-2018 SMD44_RS07920 d70cdf92faafd7fcccf81a69dbb9db5f 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS07920 d70cdf92faafd7fcccf81a69dbb9db5f 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 4.4E-26 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD44_RS09365 e6648f57433214f06aa103cf57de56ba 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 1.5E-63 T 28-03-2018 SMD44_RS09365 e6648f57433214f06aa103cf57de56ba 258 Gene3D G3DSA:3.40.50.720 3 257 3.3E-41 T 28-03-2018 SMD44_RS09365 e6648f57433214f06aa103cf57de56ba 258 SUPERFAMILY SSF51735 6 256 2.92E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09365 e6648f57433214f06aa103cf57de56ba 258 PIRSF PIRSF000094 2 258 4.1E-77 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMD44_RS08750 482c6f9802ee862022769a515382f04d 310 Pfam PF00583 Acetyltransferase (GNAT) family 42 134 1.5E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS08750 482c6f9802ee862022769a515382f04d 310 Gene3D G3DSA:3.40.630.30 164 310 4.1E-15 T 28-03-2018 SMD44_RS08750 482c6f9802ee862022769a515382f04d 310 SUPERFAMILY SSF55729 9 137 4.39E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS08750 482c6f9802ee862022769a515382f04d 310 SUPERFAMILY SSF55729 123 302 4.1E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS08750 482c6f9802ee862022769a515382f04d 310 Gene3D G3DSA:3.40.630.30 1 141 3.6E-18 T 28-03-2018 SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 Pfam PF00005 ABC transporter 24 181 5.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 Pfam PF00005 ABC transporter 296 440 1.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 SMART SM00382 304 490 5.3E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 SMART SM00382 32 231 3.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 SUPERFAMILY SSF52540 7 253 4.11E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 492 533 5.6E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 265 1.7E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 SUPERFAMILY SSF52540 276 512 9.26E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 Gene3D G3DSA:3.40.50.300 4 271 1.5E-66 T 28-03-2018 SMD44_RS28010 af5962dcec38f3c383a451ac5e376b72 567 Gene3D G3DSA:3.40.50.300 272 556 1.2E-73 T 28-03-2018 SMD44_RS36170 a8ad2227f69e1e94e5cf20273496f858 336 SUPERFAMILY SSF53067 128 304 9.07E-32 T 28-03-2018 SMD44_RS36170 a8ad2227f69e1e94e5cf20273496f858 336 Gene3D G3DSA:3.30.420.150 125 309 2.9E-38 T 28-03-2018 SMD44_RS36170 a8ad2227f69e1e94e5cf20273496f858 336 Gene3D G3DSA:3.30.420.40 1 123 2.3E-29 T 28-03-2018 SMD44_RS36170 a8ad2227f69e1e94e5cf20273496f858 336 Pfam PF02541 Ppx/GppA phosphatase family 16 302 2.0E-55 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SMD44_RS36170 a8ad2227f69e1e94e5cf20273496f858 336 SUPERFAMILY SSF53067 2 124 1.51E-24 T 28-03-2018 SMD44_RS39280 5c219a9a97ebe50b419913aa6f9e1450 423 SUPERFAMILY SSF46785 48 110 2.54E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39280 5c219a9a97ebe50b419913aa6f9e1450 423 Gene3D G3DSA:3.30.420.40 114 239 2.3E-24 T 28-03-2018 SMD44_RS39280 5c219a9a97ebe50b419913aa6f9e1450 423 SUPERFAMILY SSF53067 123 415 3.94E-44 T 28-03-2018 SMD44_RS39280 5c219a9a97ebe50b419913aa6f9e1450 423 Gene3D G3DSA:1.10.10.10 46 113 5.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39280 5c219a9a97ebe50b419913aa6f9e1450 423 Gene3D G3DSA:3.30.420.40 240 422 4.2E-50 T 28-03-2018 SMD44_RS39280 5c219a9a97ebe50b419913aa6f9e1450 423 Pfam PF00480 ROK family 123 409 8.3E-45 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS34595 5a835faaa437b9964b9fbb912a3b1b8f 607 Gene3D G3DSA:2.30.38.10 398 469 2.1E-20 T 28-03-2018 SMD44_RS34595 5a835faaa437b9964b9fbb912a3b1b8f 607 Pfam PF00501 AMP-binding enzyme 29 476 3.0E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS34595 5a835faaa437b9964b9fbb912a3b1b8f 607 Gene3D G3DSA:3.30.300.30 471 607 9.9E-17 T 28-03-2018 SMD44_RS34595 5a835faaa437b9964b9fbb912a3b1b8f 607 Gene3D G3DSA:3.40.50.980 13 188 1.3E-36 T 28-03-2018 SMD44_RS34595 5a835faaa437b9964b9fbb912a3b1b8f 607 SUPERFAMILY SSF56801 19 293 3.66E-111 T 28-03-2018 SMD44_RS34595 5a835faaa437b9964b9fbb912a3b1b8f 607 SUPERFAMILY SSF56801 347 605 3.66E-111 T 28-03-2018 SMD44_RS34595 5a835faaa437b9964b9fbb912a3b1b8f 607 Gene3D G3DSA:3.40.50.980 189 397 1.4E-38 T 28-03-2018 SMD44_RS34595 5a835faaa437b9964b9fbb912a3b1b8f 607 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS43585 15a4a436d7937bdd1de93edb0d53b757 224 Gene3D G3DSA:3.30.70.1210 96 219 7.9E-23 T 28-03-2018 SMD44_RS43585 15a4a436d7937bdd1de93edb0d53b757 224 Pfam PF08798 CRISPR associated protein 4 219 2.2E-45 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 SMD44_RS43585 15a4a436d7937bdd1de93edb0d53b757 224 Gene3D G3DSA:3.30.70.1200 1 92 3.1E-18 T 28-03-2018 SMD44_RS43585 15a4a436d7937bdd1de93edb0d53b757 224 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 29 219 8.5E-18 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 SMD44_RS43585 15a4a436d7937bdd1de93edb0d53b757 224 SUPERFAMILY SSF117987 97 219 4.18E-23 T 28-03-2018 SMD44_RS43585 15a4a436d7937bdd1de93edb0d53b757 224 SUPERFAMILY SSF117987 4 90 3.66E-17 T 28-03-2018 SMD44_RS43585 15a4a436d7937bdd1de93edb0d53b757 224 SMART SM01101 3 219 1.6E-57 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 SMD44_RS29820 7575b2f1a8823b402a2fc443b7767683 704 Pfam PF09594 Glycosyltransferase family 87 181 429 4.7E-48 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD44_RS03380 679d01d42780e65e320d1e9d225afc83 528 Gene3D G3DSA:3.20.20.140 160 477 2.5E-50 T 28-03-2018 SMD44_RS03380 679d01d42780e65e320d1e9d225afc83 528 SUPERFAMILY SSF51556 172 480 1.06E-29 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS03380 679d01d42780e65e320d1e9d225afc83 528 SUPERFAMILY SSF51556 56 113 1.06E-29 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS03380 679d01d42780e65e320d1e9d225afc83 528 SUPERFAMILY SSF51338 5 57 4.03E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS03380 679d01d42780e65e320d1e9d225afc83 528 SUPERFAMILY SSF51338 479 517 4.03E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS03380 679d01d42780e65e320d1e9d225afc83 528 Pfam PF07969 Amidohydrolase family 45 517 1.1E-80 T 28-03-2018 IPR013108 Amidohydrolase 3 SMD44_RS03380 679d01d42780e65e320d1e9d225afc83 528 Gene3D G3DSA:2.30.40.10 3 108 3.3E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS31000 3f9d7646e6e663112c62755f5e30c97a 112 Gene3D G3DSA:1.10.287.1060 11 101 2.2E-11 T 28-03-2018 SMD44_RS31000 3f9d7646e6e663112c62755f5e30c97a 112 Pfam PF06013 Proteins of 100 residues with WXG 15 72 5.3E-9 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMD44_RS31000 3f9d7646e6e663112c62755f5e30c97a 112 SUPERFAMILY SSF140453 14 97 9.68E-13 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMD44_RS06485 108a7f28ef17e28d454f8faadae4ec9b 155 Pfam PF00355 Rieske [2Fe-2S] domain 66 142 1.2E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS06485 108a7f28ef17e28d454f8faadae4ec9b 155 PRINTS PR00162 Rieske 2Fe-2S subunit signature 115 127 9.2E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS06485 108a7f28ef17e28d454f8faadae4ec9b 155 PRINTS PR00162 Rieske 2Fe-2S subunit signature 95 106 9.2E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS06485 108a7f28ef17e28d454f8faadae4ec9b 155 PRINTS PR00162 Rieske 2Fe-2S subunit signature 128 140 9.2E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS06485 108a7f28ef17e28d454f8faadae4ec9b 155 SUPERFAMILY SSF50022 62 154 1.44E-29 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS06485 108a7f28ef17e28d454f8faadae4ec9b 155 Gene3D G3DSA:2.102.10.10 24 154 5.5E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS21285 b129b6b0a5d3e1fb02a5af4a3241f0c3 385 Gene3D G3DSA:3.40.50.2000 1 180 1.8E-22 T 28-03-2018 SMD44_RS21285 b129b6b0a5d3e1fb02a5af4a3241f0c3 385 SUPERFAMILY SSF53756 1 375 3.84E-68 T 28-03-2018 SMD44_RS21285 b129b6b0a5d3e1fb02a5af4a3241f0c3 385 Gene3D G3DSA:3.40.50.2000 181 358 3.1E-37 T 28-03-2018 SMD44_RS21285 b129b6b0a5d3e1fb02a5af4a3241f0c3 385 Pfam PF13692 Glycosyl transferases group 1 194 338 8.6E-17 T 28-03-2018 SMD44_RS21285 b129b6b0a5d3e1fb02a5af4a3241f0c3 385 Pfam PF13439 Glycosyltransferase Family 4 12 171 1.2E-22 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS29340 18778511e4c735f9e1a2f6ff5796d152 548 SMART SM00382 273 400 3.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29340 18778511e4c735f9e1a2f6ff5796d152 548 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 277 397 3.8E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS29340 18778511e4c735f9e1a2f6ff5796d152 548 SUPERFAMILY SSF52540 237 469 5.18E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29340 18778511e4c735f9e1a2f6ff5796d152 548 Gene3D G3DSA:3.40.50.300 232 410 5.6E-23 T 28-03-2018 SMD44_RS07680 50169decbafd1405199b09a369c58a56 277 SUPERFAMILY SSF53850 38 277 1.87E-80 T 28-03-2018 SMD44_RS07680 50169decbafd1405199b09a369c58a56 277 Pfam PF03180 NLPA lipoprotein 38 276 2.3E-92 T 28-03-2018 IPR004872 Lipoprotein NlpA family SMD44_RS07680 50169decbafd1405199b09a369c58a56 277 PIRSF PIRSF002854 2 277 2.4E-108 T 28-03-2018 IPR004872 Lipoprotein NlpA family SMD44_RS07680 50169decbafd1405199b09a369c58a56 277 Gene3D G3DSA:3.40.190.10 135 277 8.0E-54 T 28-03-2018 SMD44_RS07680 50169decbafd1405199b09a369c58a56 277 Gene3D G3DSA:3.40.190.10 36 134 5.4E-23 T 28-03-2018 SMD44_RS19125 8f6cdca8dbfcec7b6bcbe1e5054dd5d3 153 SUPERFAMILY SSF50475 17 138 1.54E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS19125 8f6cdca8dbfcec7b6bcbe1e5054dd5d3 153 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 19 97 2.0E-10 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS19125 8f6cdca8dbfcec7b6bcbe1e5054dd5d3 153 Gene3D G3DSA:2.30.110.10 9 150 3.1E-23 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS24290 d0fa53380e2edae2d507d344792fded5 180 SUPERFAMILY SSF55729 6 162 6.49E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS24290 d0fa53380e2edae2d507d344792fded5 180 Gene3D G3DSA:3.40.630.30 2 180 3.2E-23 T 28-03-2018 SMD44_RS24290 d0fa53380e2edae2d507d344792fded5 180 Pfam PF13302 Acetyltransferase (GNAT) domain 9 146 1.1E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 PRINTS PR00127 Clp protease catalytic subunit P signature 165 184 1.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 PRINTS PR00127 Clp protease catalytic subunit P signature 108 127 1.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 PRINTS PR00127 Clp protease catalytic subunit P signature 87 104 1.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 PRINTS PR00127 Clp protease catalytic subunit P signature 56 76 1.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 1.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 SUPERFAMILY SSF52096 17 189 3.84E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 Gene3D G3DSA:3.90.226.10 19 190 2.5E-40 T 28-03-2018 SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 190 37.871 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14150 eb5b84e3088ebcb639e5f4fbe95d9a2b 201 Pfam PF00574 Clp protease 17 188 5.8E-74 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 SUPERFAMILY SSF49879 169 325 4.02E-26 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 SMART SM00382 344 538 2.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 Gene3D G3DSA:2.60.200.20 7 92 3.0E-22 T 28-03-2018 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 SUPERFAMILY SSF52540 311 553 1.49E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 Pfam PF01061 ABC-2 type transporter 608 824 4.4E-13 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 Pfam PF00498 FHA domain 25 88 1.8E-16 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 Pfam PF00498 FHA domain 231 297 5.2E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 Gene3D G3DSA:3.40.50.300 316 579 2.0E-67 T 28-03-2018 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 SUPERFAMILY SSF49879 12 90 2.68E-22 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 Pfam PF00005 ABC transporter 335 482 9.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 Gene3D G3DSA:2.60.200.20 145 311 3.8E-27 T 28-03-2018 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 SMART SM00240 24 74 5.4E-13 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS09320 88dcce5512bb484b160fd6ef9523a36e 887 SMART SM00240 229 280 1.2E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS00485 9080e58dee3ed323034376962cbc297e 476 SUPERFAMILY SSF103473 34 435 1.57E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS00485 9080e58dee3ed323034376962cbc297e 476 Pfam PF07690 Major Facilitator Superfamily 40 221 1.8E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS00485 9080e58dee3ed323034376962cbc297e 476 Gene3D G3DSA:1.20.1250.20 256 450 3.3E-9 T 28-03-2018 SMD44_RS00485 9080e58dee3ed323034376962cbc297e 476 Gene3D G3DSA:1.20.1250.20 28 222 4.5E-21 T 28-03-2018 SMD44_RS42115 2c5a76df34b8dc63e34d740ff0b3b1d1 143 Pfam PF00011 Hsp20/alpha crystallin family 35 133 2.9E-20 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain SMD44_RS42115 2c5a76df34b8dc63e34d740ff0b3b1d1 143 SUPERFAMILY SSF49764 17 133 2.48E-29 T 28-03-2018 IPR008978 HSP20-like chaperone SMD44_RS42115 2c5a76df34b8dc63e34d740ff0b3b1d1 143 Gene3D G3DSA:2.60.40.790 3 133 1.5E-27 T 28-03-2018 IPR008978 HSP20-like chaperone SMD44_RS22535 9855303fae560b14eb19eaacf0a6690d 329 SMART SM00421 260 317 1.8E-4 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22535 9855303fae560b14eb19eaacf0a6690d 329 Gene3D G3DSA:1.10.10.10 246 322 2.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22535 9855303fae560b14eb19eaacf0a6690d 329 SUPERFAMILY SSF46894 250 324 1.94E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS22535 9855303fae560b14eb19eaacf0a6690d 329 Gene3D G3DSA:3.30.870.10 108 245 0.0048 T 28-03-2018 SMD44_RS22615 e1e0df290e6de7f8df0f85abbfeb1628 137 PIRSF PIRSF017349 1 137 5.2E-66 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 SMD44_RS22615 e1e0df290e6de7f8df0f85abbfeb1628 137 Gene3D G3DSA:1.25.40.10 23 136 2.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS22615 e1e0df290e6de7f8df0f85abbfeb1628 137 Pfam PF11349 Protein of unknown function (DUF3151) 10 134 3.0E-58 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 Pfam PF03466 LysR substrate binding domain 104 273 4.2E-13 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 SUPERFAMILY SSF53850 100 275 5.07E-15 T 28-03-2018 SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 Gene3D G3DSA:3.40.190.10 84 177 3.7E-5 T 28-03-2018 SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 Gene3D G3DSA:1.10.10.10 1 83 8.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 SUPERFAMILY SSF46785 1 100 9.09E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 60 1.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS32630 7b395251e157b7a1a28282dd725de986 288 Gene3D G3DSA:3.40.190.10 178 263 2.3E-17 T 28-03-2018 SMD44_RS33365 2a01bed210f3e9ec474c9bb044a70c30 443 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 9 422 7.9E-107 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SMD44_RS33365 2a01bed210f3e9ec474c9bb044a70c30 443 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 340 360 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SMD44_RS33365 2a01bed210f3e9ec474c9bb044a70c30 443 TIGRFAM TIGR03173 pbuX: xanthine permease 14 425 9.3E-144 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 SMD44_RS33365 2a01bed210f3e9ec474c9bb044a70c30 443 Pfam PF00860 Permease family 10 392 9.2E-94 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS41865 2328314dc2946f457c0d2fa8b451c124 186 Gene3D G3DSA:1.10.10.60 1 50 7.4E-8 T 28-03-2018 SMD44_RS41865 2328314dc2946f457c0d2fa8b451c124 186 Gene3D G3DSA:1.10.357.10 51 176 5.1E-22 T 28-03-2018 SMD44_RS41865 2328314dc2946f457c0d2fa8b451c124 186 Pfam PF13305 WHG domain 74 149 2.5E-11 T 28-03-2018 IPR025996 WHG domain SMD44_RS41865 2328314dc2946f457c0d2fa8b451c124 186 SUPERFAMILY SSF46689 2 60 6.16E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS41865 2328314dc2946f457c0d2fa8b451c124 186 SUPERFAMILY SSF48498 68 174 3.5E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS41865 2328314dc2946f457c0d2fa8b451c124 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 36 2.7E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS03495 f2f58fd81e10167e0a519072ead3432d 211 Gene3D G3DSA:1.10.10.60 16 71 5.7E-19 T 28-03-2018 SMD44_RS03495 f2f58fd81e10167e0a519072ead3432d 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS03495 f2f58fd81e10167e0a519072ead3432d 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS03495 f2f58fd81e10167e0a519072ead3432d 211 SUPERFAMILY SSF48498 91 205 4.11E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS03495 f2f58fd81e10167e0a519072ead3432d 211 Gene3D G3DSA:1.10.357.10 72 209 1.2E-23 T 28-03-2018 SMD44_RS03495 f2f58fd81e10167e0a519072ead3432d 211 SUPERFAMILY SSF46689 16 93 4.05E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS03495 f2f58fd81e10167e0a519072ead3432d 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 1.9E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00750 1b48a11bb8d7e12b662381d1332953aa 179 SUPERFAMILY SSF46689 2 76 1.54E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00750 1b48a11bb8d7e12b662381d1332953aa 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 1.4E-4 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00750 1b48a11bb8d7e12b662381d1332953aa 179 Gene3D G3DSA:1.10.357.10 7 178 2.0E-18 T 28-03-2018 SMD44_RS21195 00958e1562c18b5e4c6695c0380519ac 553 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS21195 00958e1562c18b5e4c6695c0380519ac 553 Pfam PF00069 Protein kinase domain 9 248 4.2E-37 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS21195 00958e1562c18b5e4c6695c0380519ac 553 SMART SM00220 9 511 8.3E-35 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS21195 00958e1562c18b5e4c6695c0380519ac 553 SUPERFAMILY SSF56112 3 258 5.72E-60 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS21195 00958e1562c18b5e4c6695c0380519ac 553 Gene3D G3DSA:3.30.200.20 4 85 2.0E-14 T 28-03-2018 SMD44_RS21195 00958e1562c18b5e4c6695c0380519ac 553 Gene3D G3DSA:1.10.510.10 86 304 2.4E-38 T 28-03-2018 SMD44_RS39830 a6e4a67121c0154a7310d8e6a0196db9 194 SUPERFAMILY SSF46689 9 80 1.65E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS39830 a6e4a67121c0154a7310d8e6a0196db9 194 Gene3D G3DSA:1.10.260.40 47 68 2.8E-10 T 28-03-2018 SMD44_RS39830 a6e4a67121c0154a7310d8e6a0196db9 194 Gene3D G3DSA:1.10.357.10 69 190 1.6E-9 T 28-03-2018 SMD44_RS39830 a6e4a67121c0154a7310d8e6a0196db9 194 Gene3D G3DSA:1.10.10.60 4 46 9.5E-15 T 28-03-2018 SMD44_RS39830 a6e4a67121c0154a7310d8e6a0196db9 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 3.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS39830 a6e4a67121c0154a7310d8e6a0196db9 194 SUPERFAMILY SSF48498 85 189 7.63E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS28375 1757eaa55b351a900fb73450f56a583a 261 SUPERFAMILY SSF100950 2 255 2.23E-86 T 28-03-2018 SMD44_RS28375 1757eaa55b351a900fb73450f56a583a 261 Gene3D G3DSA:3.40.50.1360 1 255 9.2E-76 T 28-03-2018 SMD44_RS28375 1757eaa55b351a900fb73450f56a583a 261 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 15 246 8.2E-75 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 SMD44_RS28375 1757eaa55b351a900fb73450f56a583a 261 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 227 6.0E-23 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 SMD44_RS28375 1757eaa55b351a900fb73450f56a583a 261 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 242 38.545 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 SMD44_RS28375 1757eaa55b351a900fb73450f56a583a 261 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 SMD44_RS21465 4a35134cd517c42483bc46b963b03151 543 SUPERFAMILY SSF81606 19 251 8.76E-67 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS21465 4a35134cd517c42483bc46b963b03151 543 SMART SM00332 17 250 4.2E-29 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS21465 4a35134cd517c42483bc46b963b03151 543 SMART SM00331 26 252 1.2E-41 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS21465 4a35134cd517c42483bc46b963b03151 543 Gene3D G3DSA:3.60.40.10 20 252 1.0E-44 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS21465 4a35134cd517c42483bc46b963b03151 543 Pfam PF00481 Protein phosphatase 2C 37 245 4.3E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS08510 38ae3b8bccae49787b5bac37332c3800 347 Gene3D G3DSA:3.30.200.20 11 113 5.5E-31 T 28-03-2018 SMD44_RS08510 38ae3b8bccae49787b5bac37332c3800 347 Pfam PF01636 Phosphotransferase enzyme family 36 295 3.1E-50 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS08510 38ae3b8bccae49787b5bac37332c3800 347 Gene3D G3DSA:3.90.1200.10 114 304 2.8E-31 T 28-03-2018 SMD44_RS08510 38ae3b8bccae49787b5bac37332c3800 347 SUPERFAMILY SSF56112 10 320 4.52E-61 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 Pfam PF00919 Uncharacterized protein family UPF0004 7 105 3.8E-31 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 477 3.1E-116 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 Gene3D G3DSA:2.40.50.140 416 483 1.7E-20 T 28-03-2018 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 187 207 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 SUPERFAMILY SSF102114 173 405 2.35E-42 T 28-03-2018 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 Gene3D G3DSA:3.80.30.20 183 415 1.3E-35 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 Gene3D G3DSA:3.90.190.20 55 139 0.19 T 28-03-2018 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 181 475 1.1E-77 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 Pfam PF04055 Radical SAM superfamily 189 359 2.3E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 480 59.44 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 SMD44_RS31135 56ae882b73621e87abe43706a73fb020 509 SMART SM00729 183 401 2.3E-39 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS13875 867b1c4cf6000b078e7b2340713bff36 281 Gene3D G3DSA:3.30.1180.10 154 281 1.9E-44 T 28-03-2018 SMD44_RS13875 867b1c4cf6000b078e7b2340713bff36 281 SUPERFAMILY SSF82549 5 280 1.83E-77 T 28-03-2018 SMD44_RS13875 867b1c4cf6000b078e7b2340713bff36 281 Gene3D G3DSA:3.40.50.10170 1 153 6.5E-46 T 28-03-2018 SMD44_RS13875 867b1c4cf6000b078e7b2340713bff36 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 280 1.9E-87 T 28-03-2018 IPR003797 DegV SMD44_RS13875 867b1c4cf6000b078e7b2340713bff36 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 278 5.0E-88 T 28-03-2018 IPR003797 DegV SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Gene3D G3DSA:2.10.10.20 1017 1060 2.9E-13 T 28-03-2018 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 346 506 2.6E-26 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Gene3D G3DSA:3.40.630.10 626 911 1.4E-58 T 28-03-2018 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Gene3D G3DSA:3.10.170.10 196 339 1.9E-30 T 28-03-2018 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Pfam PF04389 Peptidase family M28 693 898 2.6E-42 T 28-03-2018 IPR007484 Peptidase M28 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Gene3D G3DSA:1.10.390.10 341 507 1.3E-31 T 28-03-2018 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 SUPERFAMILY SSF55486 197 506 2.8E-53 T 28-03-2018 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 68 109 1.0E-6 T 28-03-2018 IPR011096 FTP domain SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Gene3D G3DSA:2.60.40.10 912 1009 5.4E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Gene3D G3DSA:2.60.40.10 521 624 1.2E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 SUPERFAMILY SSF53187 635 903 7.43E-60 T 28-03-2018 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 SUPERFAMILY SSF51055 1018 1060 1.12E-15 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 SMART SM00495 1015 1061 3.7E-10 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD44_RS36385 25a322fbc44278e3072ec266cd5d0feb 1061 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 198 333 1.2E-24 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 SUPERFAMILY SSF52317 5 197 5.38E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 SUPERFAMILY SSF46689 269 316 2.69E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 Pfam PF01965 DJ-1/PfpI family 5 176 6.1E-25 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 Gene3D G3DSA:3.40.50.880 1 215 3.5E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 Pfam PF12833 Helix-turn-helix domain 238 309 7.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 Gene3D G3DSA:1.10.10.60 273 316 7.6E-8 T 28-03-2018 SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 SMART SM00342 232 315 2.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 Gene3D G3DSA:1.10.10.60 216 272 3.5E-10 T 28-03-2018 SMD44_RS17665 8227d1379fbdcf779ac963486f0df53a 334 SUPERFAMILY SSF46689 216 263 5.02E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS06865 d39f94a11b41e4e3caf95fb98e41adf8 523 Gene3D G3DSA:3.40.50.300 262 461 5.6E-12 T 28-03-2018 SMD44_RS06865 d39f94a11b41e4e3caf95fb98e41adf8 523 SUPERFAMILY SSF52540 221 489 3.09E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS22580 ed4798b15f8cba0225be7fbeb0051101 173 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 4 168 1.0E-76 T 28-03-2018 IPR024486 Protein of unknown function DUF2617 SMD44_RS22580 ed4798b15f8cba0225be7fbeb0051101 173 Pfam PF10936 Protein of unknown function DUF2617 3 165 1.0E-59 T 28-03-2018 IPR024486 Protein of unknown function DUF2617 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 Gene3D G3DSA:3.40.50.1820 3 280 2.1E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 Pfam PF00561 alpha/beta hydrolase fold 26 266 1.4E-32 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 3.5E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 3.5E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 3.5E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 PRINTS PR00412 Epoxide hydrolase signature 255 277 3.0E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 PRINTS PR00412 Epoxide hydrolase signature 51 66 3.0E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 PRINTS PR00412 Epoxide hydrolase signature 31 49 3.0E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 PRINTS PR00412 Epoxide hydrolase signature 221 237 3.0E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS02725 75971006b180ef109dd1ef21516c575d 280 SUPERFAMILY SSF53474 12 279 4.65E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01510 ef533eeb8499b853f46df45cc31233a7 316 Gene3D G3DSA:1.10.3720.10 30 303 1.4E-40 T 28-03-2018 SMD44_RS01510 ef533eeb8499b853f46df45cc31233a7 316 SUPERFAMILY SSF161098 38 315 3.92E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS01510 ef533eeb8499b853f46df45cc31233a7 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 300 7.3E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS37300 975e2d2e8010606e4c995205f75d6f65 156 PRINTS PR01438 Universal stress protein signature 134 156 1.4E-6 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS37300 975e2d2e8010606e4c995205f75d6f65 156 PRINTS PR01438 Universal stress protein signature 19 37 1.4E-6 T 28-03-2018 IPR006015 Universal stress protein A SMD44_RS37300 975e2d2e8010606e4c995205f75d6f65 156 Pfam PF00582 Universal stress protein family 20 156 5.4E-21 T 28-03-2018 IPR006016 UspA GO:0006950 SMD44_RS37300 975e2d2e8010606e4c995205f75d6f65 156 Gene3D G3DSA:3.40.50.620 3 156 8.7E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS37300 975e2d2e8010606e4c995205f75d6f65 156 SUPERFAMILY SSF52402 20 156 2.18E-23 T 28-03-2018 SMD44_RS30420 ae18eca1fa2bf16a1fb6699a1175255d 225 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 37 202 7.3E-16 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS30420 ae18eca1fa2bf16a1fb6699a1175255d 225 SMART SM00943 35 213 4.2E-33 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS34155 6c9d5f976451bae85a847dd7840b3a29 376 Pfam PF03747 ADP-ribosylglycohydrolase 16 320 2.8E-51 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS34155 6c9d5f976451bae85a847dd7840b3a29 376 Gene3D G3DSA:1.10.4080.10 8 362 1.4E-59 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS34155 6c9d5f976451bae85a847dd7840b3a29 376 SUPERFAMILY SSF101478 9 352 6.54E-42 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS33450 61f7066c85290e28f009b6f695acf504 224 Gene3D G3DSA:1.10.10.10 159 224 1.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33450 61f7066c85290e28f009b6f695acf504 224 SMART SM00421 164 221 8.5E-4 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS33450 61f7066c85290e28f009b6f695acf504 224 SUPERFAMILY SSF46894 161 221 8.5E-6 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS42590 bb5d5b635e5583286130c128f33823e9 283 SUPERFAMILY SSF47413 7 71 1.17E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS42590 bb5d5b635e5583286130c128f33823e9 283 SMART SM00530 74 128 0.034 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS42590 bb5d5b635e5583286130c128f33823e9 283 SMART SM00530 11 66 1.5E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS42590 bb5d5b635e5583286130c128f33823e9 283 Gene3D G3DSA:3.30.1190.10 36 74 0.0011 T 28-03-2018 SMD44_RS42590 bb5d5b635e5583286130c128f33823e9 283 Gene3D G3DSA:1.10.10.60 9 35 2.0E-5 T 28-03-2018 SMD44_RS42590 bb5d5b635e5583286130c128f33823e9 283 Gene3D G3DSA:1.10.260.40 75 132 3.5E-4 T 28-03-2018 SMD44_RS42590 bb5d5b635e5583286130c128f33823e9 283 Gene3D G3DSA:1.10.260.40 168 233 0.12 T 28-03-2018 SMD44_RS42590 bb5d5b635e5583286130c128f33823e9 283 Pfam PF01381 Helix-turn-helix 23 65 4.7E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS25540 c41fffdb54364650d40915c6e95b4633 74 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 17.986 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25540 c41fffdb54364650d40915c6e95b4633 74 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25540 c41fffdb54364650d40915c6e95b4633 74 SUPERFAMILY SSF46561 5 67 3.27E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25540 c41fffdb54364650d40915c6e95b4633 74 Pfam PF00831 Ribosomal L29 protein 8 64 4.6E-26 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25540 c41fffdb54364650d40915c6e95b4633 74 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 5.5E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25540 c41fffdb54364650d40915c6e95b4633 74 Gene3D G3DSA:1.10.287.310 5 69 3.6E-27 T 28-03-2018 SMD44_RS09795 1b3042de7edfe6822a76f88c25ff0ea0 570 SUPERFAMILY SSF143975 5 372 9.15E-116 T 28-03-2018 SMD44_RS09795 1b3042de7edfe6822a76f88c25ff0ea0 570 SUPERFAMILY SSF52016 373 558 9.42E-58 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD44_RS09795 1b3042de7edfe6822a76f88c25ff0ea0 570 Pfam PF00920 Dehydratase family 37 553 2.5E-170 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD44_RS09795 1b3042de7edfe6822a76f88c25ff0ea0 570 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 120 130 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD44_RS25735 0b40f4c78b72f18e6cc406df86c7e20e 196 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 149 2.0E-29 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 SMD44_RS25735 0b40f4c78b72f18e6cc406df86c7e20e 196 Pfam PF00583 Acetyltransferase (GNAT) family 13 129 3.9E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS25735 0b40f4c78b72f18e6cc406df86c7e20e 196 Gene3D G3DSA:3.40.630.30 1 174 3.2E-30 T 28-03-2018 SMD44_RS25735 0b40f4c78b72f18e6cc406df86c7e20e 196 SUPERFAMILY SSF55729 5 152 7.98E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS22740 f51abed454b22267ee6f4b9bba277cf3 452 Pfam PF00202 Aminotransferase class-III 33 444 2.6E-95 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS22740 f51abed454b22267ee6f4b9bba277cf3 452 Gene3D G3DSA:3.90.1150.10 4 194 1.2E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS22740 f51abed454b22267ee6f4b9bba277cf3 452 Gene3D G3DSA:3.40.640.10 195 322 5.4E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS22740 f51abed454b22267ee6f4b9bba277cf3 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 286 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS22740 f51abed454b22267ee6f4b9bba277cf3 452 Gene3D G3DSA:3.90.1150.10 323 452 2.4E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS22740 f51abed454b22267ee6f4b9bba277cf3 452 SUPERFAMILY SSF53383 20 445 1.93E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS36600 433bb3a189ff558e224a6cce34388b16 192 Pfam PF03745 Domain of unknown function (DUF309) 58 115 2.1E-18 T 28-03-2018 IPR005500 Protein of unknown function DUF309 SMD44_RS36600 433bb3a189ff558e224a6cce34388b16 192 SUPERFAMILY SSF140663 39 160 3.79E-24 T 28-03-2018 IPR023203 TTHA0068-like domain SMD44_RS36600 433bb3a189ff558e224a6cce34388b16 192 Gene3D G3DSA:1.10.3450.10 11 178 7.1E-44 T 28-03-2018 IPR023203 TTHA0068-like domain SMD44_RS18725 113b0ca5ddbff582871198f4ff9b218e 219 Gene3D G3DSA:2.60.40.10 25 105 0.051 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS18725 113b0ca5ddbff582871198f4ff9b218e 219 Gene3D G3DSA:2.60.40.10 116 182 0.0037 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS21720 b9adbfe3d120da9a6ac75c0fc8544726 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 5.9E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21720 b9adbfe3d120da9a6ac75c0fc8544726 197 Gene3D G3DSA:1.10.10.60 1 64 2.2E-19 T 28-03-2018 SMD44_RS21720 b9adbfe3d120da9a6ac75c0fc8544726 197 SUPERFAMILY SSF46689 3 84 1.08E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS21720 b9adbfe3d120da9a6ac75c0fc8544726 197 SUPERFAMILY SSF48498 81 195 2.16E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS21720 b9adbfe3d120da9a6ac75c0fc8544726 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21720 b9adbfe3d120da9a6ac75c0fc8544726 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21720 b9adbfe3d120da9a6ac75c0fc8544726 197 Gene3D G3DSA:1.10.357.10 65 196 2.5E-21 T 28-03-2018 SMD44_RS03720 274844dfc45012859b39b4b4e1cee367 210 Pfam PF08281 Sigma-70, region 4 140 191 1.1E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS03720 274844dfc45012859b39b4b4e1cee367 210 Pfam PF04542 Sigma-70 region 2 36 106 4.0E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS03720 274844dfc45012859b39b4b4e1cee367 210 Gene3D G3DSA:1.10.10.10 109 198 1.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03720 274844dfc45012859b39b4b4e1cee367 210 Gene3D G3DSA:1.10.1740.10 13 108 5.4E-19 T 28-03-2018 SMD44_RS03720 274844dfc45012859b39b4b4e1cee367 210 SUPERFAMILY SSF88946 23 115 1.22E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS03720 274844dfc45012859b39b4b4e1cee367 210 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 195 1.2E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS03720 274844dfc45012859b39b4b4e1cee367 210 SUPERFAMILY SSF88659 132 196 1.87E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS01335 0db03789889534d4124fd9f1b9f086b5 185 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 3.2E-12 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS01335 0db03789889534d4124fd9f1b9f086b5 185 SUPERFAMILY SSF46785 3 179 4.95E-40 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01335 0db03789889534d4124fd9f1b9f086b5 185 Gene3D G3DSA:1.10.10.10 1 92 1.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01335 0db03789889534d4124fd9f1b9f086b5 185 Pfam PF10400 Virulence activator alpha C-term 92 179 5.8E-25 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal SMD44_RS32635 2722fc6f30ed60bb65584ad1845bc4a4 266 Gene3D G3DSA:2.30.42.10 77 266 1.1E-11 T 28-03-2018 SMD44_RS32635 2722fc6f30ed60bb65584ad1845bc4a4 266 SUPERFAMILY SSF50156 179 257 2.29E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS32635 2722fc6f30ed60bb65584ad1845bc4a4 266 SMART SM00228 180 252 0.0033 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS32635 2722fc6f30ed60bb65584ad1845bc4a4 266 Pfam PF13180 PDZ domain 180 253 2.0E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS27400 3ba1c4064ba92588e32693440cbaef80 314 Pfam PF04672 S-adenosyl methyltransferase 69 312 8.0E-69 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS27400 3ba1c4064ba92588e32693440cbaef80 314 Gene3D G3DSA:3.40.50.150 55 313 7.5E-38 T 28-03-2018 SMD44_RS27400 3ba1c4064ba92588e32693440cbaef80 314 SUPERFAMILY SSF53335 71 296 1.02E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS27400 3ba1c4064ba92588e32693440cbaef80 314 PIRSF PIRSF017393 53 313 1.2E-68 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS18080 996fd6ed3c775fd428088697712e955e 314 Pfam PF04199 Putative cyclase 94 245 1.9E-20 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 SMD44_RS18080 996fd6ed3c775fd428088697712e955e 314 SUPERFAMILY SSF102198 97 313 3.14E-21 T 28-03-2018 SMD44_RS18080 996fd6ed3c775fd428088697712e955e 314 Gene3D G3DSA:3.50.30.50 51 314 8.1E-46 T 28-03-2018 SMD44_RS19615 86f38504a39ddab82759ad476580f0ed 373 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 167 367 2.2E-41 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19615 86f38504a39ddab82759ad476580f0ed 373 SUPERFAMILY SSF81606 156 366 4.45E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19615 86f38504a39ddab82759ad476580f0ed 373 SMART SM00331 141 367 1.6E-24 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19615 86f38504a39ddab82759ad476580f0ed 373 Gene3D G3DSA:3.60.40.10 104 370 2.4E-31 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS02015 0c3e0d54d6bdb3bed0ee9c9ddb4e519b 295 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 56 67 2.7E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS02015 0c3e0d54d6bdb3bed0ee9c9ddb4e519b 295 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 113 130 2.7E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS02015 0c3e0d54d6bdb3bed0ee9c9ddb4e519b 295 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 140 153 2.7E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS02015 0c3e0d54d6bdb3bed0ee9c9ddb4e519b 295 Gene3D G3DSA:3.40.710.10 18 293 4.1E-45 T 28-03-2018 SMD44_RS02015 0c3e0d54d6bdb3bed0ee9c9ddb4e519b 295 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 50 254 2.9E-31 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD44_RS02015 0c3e0d54d6bdb3bed0ee9c9ddb4e519b 295 SUPERFAMILY SSF56601 48 257 3.09E-41 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS41165 c6bb2f4428650d9ff4d27a1f0e16f798 343 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 7 127 4.3E-16 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 SMD44_RS41165 c6bb2f4428650d9ff4d27a1f0e16f798 343 SUPERFAMILY SSF51735 5 149 2.12E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS41165 c6bb2f4428650d9ff4d27a1f0e16f798 343 Gene3D G3DSA:3.40.50.720 1 153 1.7E-23 T 28-03-2018 SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 Gene3D G3DSA:3.40.50.720 48 261 3.7E-58 T 28-03-2018 SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 Gene3D G3DSA:3.40.50.720 1 47 1.6E-7 T 28-03-2018 SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 SUPERFAMILY SSF51735 5 257 9.72E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 255 1.8E-60 T 28-03-2018 SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 6.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17870 a3a4726ea8e9d41f8ead3477724939cf 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS01100 e49dcdcb1401ef2868bda1e94d1b1306 208 Pfam PF07931 Chloramphenicol phosphotransferase-like protein 35 207 1.1E-63 T 28-03-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 SMD44_RS01100 e49dcdcb1401ef2868bda1e94d1b1306 208 SUPERFAMILY SSF52540 35 196 4.13E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS01100 e49dcdcb1401ef2868bda1e94d1b1306 208 PIRSF PIRSF007531 8 208 1.3E-68 T 28-03-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 SMD44_RS01100 e49dcdcb1401ef2868bda1e94d1b1306 208 Gene3D G3DSA:3.40.50.300 32 208 1.7E-18 T 28-03-2018 SMD44_RS14910 843986ff3b29de1dd8fe617b09d4d05b 574 Pfam PF07905 Purine catabolism regulatory protein-like family 22 145 3.5E-23 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain SMD44_RS14910 843986ff3b29de1dd8fe617b09d4d05b 574 Pfam PF13556 PucR C-terminal helix-turn-helix domain 513 567 1.9E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS38235 1cf62b9acc983dd04687106bde5191b8 474 SUPERFAMILY SSF53850 32 472 1.26E-53 T 28-03-2018 SMD44_RS38235 1cf62b9acc983dd04687106bde5191b8 474 Gene3D G3DSA:3.40.190.10 259 444 0.11 T 28-03-2018 SMD44_RS38235 1cf62b9acc983dd04687106bde5191b8 474 Gene3D G3DSA:3.40.190.10 63 258 3.7E-32 T 28-03-2018 SMD44_RS38445 04a474ac4ba6ae52426ccf7db1da7787 118 PIRSF PIRSF009151 1 118 2.2E-59 T 28-03-2018 IPR008497 Protein of unknown function DUF779 SMD44_RS38445 04a474ac4ba6ae52426ccf7db1da7787 118 Pfam PF05610 Protein of unknown function (DUF779) 16 115 2.7E-47 T 28-03-2018 IPR008497 Protein of unknown function DUF779 SMD44_RS14700 2aeb0ec87ec7083fb8e41426c6c6c2d6 408 Gene3D G3DSA:3.40.50.1100 95 222 5.0E-19 T 28-03-2018 SMD44_RS14700 2aeb0ec87ec7083fb8e41426c6c6c2d6 408 SUPERFAMILY SSF53686 48 385 4.71E-60 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS14700 2aeb0ec87ec7083fb8e41426c6c6c2d6 408 Gene3D G3DSA:3.40.50.1100 223 388 3.8E-27 T 28-03-2018 SMD44_RS14700 2aeb0ec87ec7083fb8e41426c6c6c2d6 408 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 88 375 3.0E-54 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS20780 98e1f6b625e002284dd3f480254c70b1 337 Gene3D G3DSA:1.10.1660.10 85 135 8.1E-5 T 28-03-2018 SMD44_RS20780 98e1f6b625e002284dd3f480254c70b1 337 Pfam PF13411 MerR HTH family regulatory protein 30 97 7.5E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS20780 98e1f6b625e002284dd3f480254c70b1 337 SUPERFAMILY SSF46955 30 101 4.4E-17 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS20780 98e1f6b625e002284dd3f480254c70b1 337 SMART SM00422 30 98 4.9E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS20780 98e1f6b625e002284dd3f480254c70b1 337 Gene3D G3DSA:1.10.1660.10 27 84 3.5E-17 T 28-03-2018 SMD44_RS06050 8b0afe8291416fb89f9d35245b803690 526 Gene3D G3DSA:3.60.21.10 145 524 1.5E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS06050 8b0afe8291416fb89f9d35245b803690 526 Pfam PF09423 PhoD-like phosphatase 156 503 3.2E-76 T 28-03-2018 IPR018946 Alkaline phosphatase D-related SMD44_RS06050 8b0afe8291416fb89f9d35245b803690 526 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 49 139 6.9E-14 T 28-03-2018 IPR032093 Phospholipase D, N-terminal SMD44_RS06050 8b0afe8291416fb89f9d35245b803690 526 SUPERFAMILY SSF56300 145 519 5.22E-38 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS29705 b9ac49f901cfe357e7e8a327d1f94d0b 362 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 256 317 2.8E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS29705 b9ac49f901cfe357e7e8a327d1f94d0b 362 Pfam PF00005 ABC transporter 42 204 2.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS29705 b9ac49f901cfe357e7e8a327d1f94d0b 362 SUPERFAMILY SSF52540 22 275 2.77E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29705 b9ac49f901cfe357e7e8a327d1f94d0b 362 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 255 345 5.1E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS29705 b9ac49f901cfe357e7e8a327d1f94d0b 362 SMART SM00382 50 254 9.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29705 b9ac49f901cfe357e7e8a327d1f94d0b 362 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS29705 b9ac49f901cfe357e7e8a327d1f94d0b 362 Gene3D G3DSA:3.40.50.300 19 360 2.8E-79 T 28-03-2018 SMD44_RS28990 f206be2aa1cdf6fb17f5b8e7de44eb48 388 Pfam PF00005 ABC transporter 19 156 1.6E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS28990 f206be2aa1cdf6fb17f5b8e7de44eb48 388 SUPERFAMILY SSF52540 2 220 5.61E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28990 f206be2aa1cdf6fb17f5b8e7de44eb48 388 SMART SM00382 26 213 7.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS28990 f206be2aa1cdf6fb17f5b8e7de44eb48 388 Gene3D G3DSA:3.40.50.300 1 258 5.4E-53 T 28-03-2018 SMD44_RS06610 7caeb1c6a781bf5100fa50b3a0188f35 157 Pfam PF02577 Bifunctional nuclease 6 128 5.1E-45 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 SMD44_RS06610 7caeb1c6a781bf5100fa50b3a0188f35 157 SUPERFAMILY SSF103256 3 136 2.22E-46 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 SMD44_RS12670 1115c6986e2d688d676d8c069c97e73f 298 Gene3D G3DSA:2.60.60.30 15 175 3.2E-43 T 28-03-2018 SMD44_RS12670 1115c6986e2d688d676d8c069c97e73f 298 Pfam PF02342 TerD domain 1 176 3.6E-43 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS24185 4e24e1c0738e8899d587bc4040f78ac0 558 Pfam PF13560 Helix-turn-helix domain 54 117 4.4E-12 T 28-03-2018 SMD44_RS24185 4e24e1c0738e8899d587bc4040f78ac0 558 SUPERFAMILY SSF47413 58 121 7.62E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS24185 4e24e1c0738e8899d587bc4040f78ac0 558 SMART SM00530 58 114 2.3E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS24185 4e24e1c0738e8899d587bc4040f78ac0 558 Gene3D G3DSA:1.10.260.40 53 118 4.6E-9 T 28-03-2018 SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 Pfam PF13377 Periplasmic binding protein-like domain 165 321 8.2E-31 T 28-03-2018 SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 28-03-2018 SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 SUPERFAMILY SSF53822 58 321 5.55E-63 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 SUPERFAMILY SSF47413 1 56 2.81E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 Gene3D G3DSA:3.40.50.2300 172 323 1.4E-38 T 28-03-2018 SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 SMART SM00354 1 68 3.2E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 Gene3D G3DSA:3.40.50.2300 53 171 4.8E-34 T 28-03-2018 SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 7.0E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS04800 56a5abbbb08862d787c29acd5e5e7e31 328 Gene3D G3DSA:1.10.260.40 1 52 3.4E-21 T 28-03-2018 SMD44_RS20100 1b40b72335793c3a3a7484ba2a23b1cd 374 Gene3D G3DSA:3.40.50.450 3 150 2.0E-16 T 28-03-2018 SMD44_RS20100 1b40b72335793c3a3a7484ba2a23b1cd 374 Gene3D G3DSA:1.10.287.1060 151 241 0.017 T 28-03-2018 SMD44_RS05710 1feb9f0e98b97df87f3f69d96b864071 306 Pfam PF08378 Nuclease-related domain 148 252 1.8E-13 T 28-03-2018 IPR011528 Nuclease-related domain, NERD SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 Gene3D G3DSA:1.10.3110.10 135 215 7.3E-24 T 28-03-2018 SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 Pfam PF01593 Flavin containing amine oxidoreductase 35 477 4.0E-50 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 SUPERFAMILY SSF51905 27 335 1.48E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 SUPERFAMILY SSF51905 446 478 1.48E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 Gene3D G3DSA:3.90.660.20 249 429 4.9E-42 T 28-03-2018 SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 27 477 2.8E-62 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 Gene3D G3DSA:3.90.660.20 73 134 7.6E-6 T 28-03-2018 SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 Gene3D G3DSA:3.50.50.60 20 72 4.1E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32400 c9bd9a1d9ee7d6b28adb97edb15ee837 501 SUPERFAMILY SSF54373 319 429 6.08E-27 T 28-03-2018 SMD44_RS39790 9474710a913ecc16201414c68beda6b3 312 Pfam PF04909 Amidohydrolase 6 299 1.0E-33 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS39790 9474710a913ecc16201414c68beda6b3 312 Gene3D G3DSA:3.20.20.140 1 307 5.9E-46 T 28-03-2018 SMD44_RS39790 9474710a913ecc16201414c68beda6b3 312 SUPERFAMILY SSF51556 4 304 3.26E-42 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS23605 800c01e0ead3e6d36f52b61f0ac6a911 394 SMART SM00833 252 368 1.6E-39 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS23605 800c01e0ead3e6d36f52b61f0ac6a911 394 SUPERFAMILY SSF90002 253 315 8.37E-11 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS23605 800c01e0ead3e6d36f52b61f0ac6a911 394 SUPERFAMILY SSF90002 342 368 8.37E-11 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS23605 800c01e0ead3e6d36f52b61f0ac6a911 394 Gene3D G3DSA:3.30.1220.10 230 369 9.3E-21 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS23605 800c01e0ead3e6d36f52b61f0ac6a911 394 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 253 368 1.5E-20 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD44_RS23605 800c01e0ead3e6d36f52b61f0ac6a911 394 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 79 197 1.5E-4 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMD44_RS23605 800c01e0ead3e6d36f52b61f0ac6a911 394 Gene3D G3DSA:3.40.50.300 18 228 6.6E-9 T 28-03-2018 SMD44_RS23750 7f32db9f1b20ef9f2be865756c60f7b1 387 Gene3D G3DSA:3.40.50.300 1 240 4.1E-74 T 28-03-2018 SMD44_RS23750 7f32db9f1b20ef9f2be865756c60f7b1 387 SUPERFAMILY SSF54631 275 364 6.33E-8 T 28-03-2018 SMD44_RS23750 7f32db9f1b20ef9f2be865756c60f7b1 387 SUPERFAMILY SSF52540 1 239 3.93E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23750 7f32db9f1b20ef9f2be865756c60f7b1 387 Pfam PF00005 ABC transporter 19 164 1.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS23750 7f32db9f1b20ef9f2be865756c60f7b1 387 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 362 8.6E-100 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMD44_RS23750 7f32db9f1b20ef9f2be865756c60f7b1 387 SMART SM00382 27 214 2.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS23750 7f32db9f1b20ef9f2be865756c60f7b1 387 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS23750 7f32db9f1b20ef9f2be865756c60f7b1 387 Gene3D G3DSA:3.10.580.10 241 377 4.4E-5 T 28-03-2018 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 PRINTS PR00162 Rieske 2Fe-2S subunit signature 484 496 3.0E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 PRINTS PR00162 Rieske 2Fe-2S subunit signature 463 474 3.0E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 PRINTS PR00162 Rieske 2Fe-2S subunit signature 496 508 3.0E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 Pfam PF00355 Rieske [2Fe-2S] domain 429 509 3.0E-16 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 Gene3D G3DSA:3.50.50.60 19 413 1.8E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 Gene3D G3DSA:2.102.10.10 414 518 1.7E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 Pfam PF01266 FAD dependent oxidoreductase 32 380 3.3E-45 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 SUPERFAMILY SSF51905 31 237 9.45E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 SUPERFAMILY SSF51905 342 412 9.45E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS32670 ea0cd69075f4d3b077eb333264b0f730 522 SUPERFAMILY SSF50022 425 513 1.23E-26 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS25505 7e0b04b10e723cf3c360d79c5812fc3f 218 SUPERFAMILY SSF52166 1 205 4.19E-73 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SMD44_RS25505 7e0b04b10e723cf3c360d79c5812fc3f 218 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 209 33.379 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25505 7e0b04b10e723cf3c360d79c5812fc3f 218 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 2.3E-63 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 SMD44_RS25505 7e0b04b10e723cf3c360d79c5812fc3f 218 Gene3D G3DSA:3.40.1370.10 147 206 1.0E-11 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SMD44_RS25505 7e0b04b10e723cf3c360d79c5812fc3f 218 Gene3D G3DSA:3.40.1370.10 2 146 2.3E-50 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SMD44_RS25505 7e0b04b10e723cf3c360d79c5812fc3f 218 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 6.7E-70 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS36905 1bc425da5f3b66ea9a3369841f60339d 478 ProSitePatterns PS00455 Putative AMP-binding domain signature. 135 146 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS36905 1bc425da5f3b66ea9a3369841f60339d 478 Gene3D G3DSA:3.30.300.30 377 469 9.7E-17 T 28-03-2018 SMD44_RS36905 1bc425da5f3b66ea9a3369841f60339d 478 Gene3D G3DSA:3.40.50.980 3 141 7.0E-23 T 28-03-2018 SMD44_RS36905 1bc425da5f3b66ea9a3369841f60339d 478 Pfam PF00501 AMP-binding enzyme 9 371 1.6E-67 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS36905 1bc425da5f3b66ea9a3369841f60339d 478 Gene3D G3DSA:3.40.50.980 142 290 4.7E-32 T 28-03-2018 SMD44_RS36905 1bc425da5f3b66ea9a3369841f60339d 478 Gene3D G3DSA:2.30.38.10 291 370 1.2E-19 T 28-03-2018 SMD44_RS36905 1bc425da5f3b66ea9a3369841f60339d 478 SUPERFAMILY SSF56801 6 469 1.96E-94 T 28-03-2018 SMD44_RS36905 1bc425da5f3b66ea9a3369841f60339d 478 Pfam PF13193 AMP-binding enzyme C-terminal domain 394 456 1.2E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS14935 729b3d9036f3e9225ddd24363d024352 291 Gene3D G3DSA:3.10.129.10 133 289 1.2E-48 T 28-03-2018 SMD44_RS14935 729b3d9036f3e9225ddd24363d024352 291 Gene3D G3DSA:3.10.129.10 2 116 6.0E-46 T 28-03-2018 SMD44_RS14935 729b3d9036f3e9225ddd24363d024352 291 SUPERFAMILY SSF54637 116 289 5.1E-45 T 28-03-2018 IPR029069 HotDog domain SMD44_RS14935 729b3d9036f3e9225ddd24363d024352 291 SUPERFAMILY SSF54637 6 114 1.42E-42 T 28-03-2018 IPR029069 HotDog domain SMD44_RS14935 729b3d9036f3e9225ddd24363d024352 291 Pfam PF13622 Thioesterase-like superfamily 33 285 6.2E-62 T 28-03-2018 SMD44_RS11730 c9c9bfe160a5ce9c047e330ed42f3646 303 SMART SM00342 195 283 3.7E-10 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS11730 c9c9bfe160a5ce9c047e330ed42f3646 303 Gene3D G3DSA:1.10.10.60 139 234 1.9E-7 T 28-03-2018 SMD44_RS11730 c9c9bfe160a5ce9c047e330ed42f3646 303 SUPERFAMILY SSF46689 247 284 2.96E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS11730 c9c9bfe160a5ce9c047e330ed42f3646 303 Gene3D G3DSA:1.10.10.60 235 292 1.1E-8 T 28-03-2018 SMD44_RS11730 c9c9bfe160a5ce9c047e330ed42f3646 303 Pfam PF12833 Helix-turn-helix domain 201 283 1.5E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS11730 c9c9bfe160a5ce9c047e330ed42f3646 303 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 237 279 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS29095 9eb2040fbb6a2b77ffb5db10a53ff447 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 8.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29095 9eb2040fbb6a2b77ffb5db10a53ff447 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29095 9eb2040fbb6a2b77ffb5db10a53ff447 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS29095 9eb2040fbb6a2b77ffb5db10a53ff447 215 Gene3D G3DSA:1.10.357.10 1 214 4.5E-24 T 28-03-2018 SMD44_RS29095 9eb2040fbb6a2b77ffb5db10a53ff447 215 SUPERFAMILY SSF46689 4 82 6.16E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS23585 6ea113bd45b41883115acccfa8225cd8 101 Gene3D G3DSA:4.10.830.10 1 101 4.5E-29 T 28-03-2018 SMD44_RS23585 6ea113bd45b41883115acccfa8225cd8 101 SUPERFAMILY SSF57716 2 101 6.7E-32 T 28-03-2018 SMD44_RS23585 6ea113bd45b41883115acccfa8225cd8 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.13 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid SMD44_RS23585 6ea113bd45b41883115acccfa8225cd8 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 2.2E-20 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD44_RS08195 a6f512dedcee7eb9e1b30e90dd691917 293 SUPERFAMILY SSF52980 42 199 5.25E-10 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS08195 a6f512dedcee7eb9e1b30e90dd691917 293 Pfam PF12705 PD-(D/E)XK nuclease superfamily 16 264 1.1E-38 T 28-03-2018 SMD44_RS08195 a6f512dedcee7eb9e1b30e90dd691917 293 Gene3D G3DSA:3.90.320.10 2 207 2.7E-31 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMD44_RS02165 c2b18c02402eeac786a2640f873074e6 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 6.4E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02165 c2b18c02402eeac786a2640f873074e6 198 Gene3D G3DSA:1.10.10.60 1 39 4.9E-16 T 28-03-2018 SMD44_RS02165 c2b18c02402eeac786a2640f873074e6 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02165 c2b18c02402eeac786a2640f873074e6 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02165 c2b18c02402eeac786a2640f873074e6 198 SUPERFAMILY SSF46689 6 90 1.03E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS02165 c2b18c02402eeac786a2640f873074e6 198 Gene3D G3DSA:1.10.357.10 71 198 1.9E-19 T 28-03-2018 SMD44_RS02165 c2b18c02402eeac786a2640f873074e6 198 Gene3D G3DSA:1.10.260.40 40 70 8.0E-14 T 28-03-2018 SMD44_RS43500 4359246b625dc0a156dff6df84e5b84c 240 Gene3D G3DSA:3.40.50.410 39 229 7.3E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS43500 4359246b625dc0a156dff6df84e5b84c 240 SUPERFAMILY SSF53300 45 199 4.13E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS43500 4359246b625dc0a156dff6df84e5b84c 240 Pfam PF10138 vWA found in TerF C terminus 44 238 1.4E-33 T 28-03-2018 IPR019303 vWA found in TerF C terminus SMD44_RS41995 27df1752bcbafc2332d62a47468256df 101 Pfam PF08386 TAP-like protein 11 101 3.9E-22 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD44_RS41995 27df1752bcbafc2332d62a47468256df 101 Gene3D G3DSA:3.40.50.1820 4 93 1.6E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS41995 27df1752bcbafc2332d62a47468256df 101 SUPERFAMILY SSF53474 32 75 7.1E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06480 1d53265ddcdc7e8f44a89c8a58999a1c 759 SUPERFAMILY SSF53474 515 757 9.65E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06480 1d53265ddcdc7e8f44a89c8a58999a1c 759 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 140 371 2.9E-21 T 28-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SMD44_RS06480 1d53265ddcdc7e8f44a89c8a58999a1c 759 Gene3D G3DSA:2.140.10.30 7 498 1.0E-45 T 28-03-2018 SMD44_RS06480 1d53265ddcdc7e8f44a89c8a58999a1c 759 Pfam PF00326 Prolyl oligopeptidase family 560 758 8.0E-47 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD44_RS06480 1d53265ddcdc7e8f44a89c8a58999a1c 759 SUPERFAMILY SSF82171 116 288 6.8E-24 T 28-03-2018 SMD44_RS06480 1d53265ddcdc7e8f44a89c8a58999a1c 759 SUPERFAMILY SSF82171 323 466 6.8E-24 T 28-03-2018 SMD44_RS06480 1d53265ddcdc7e8f44a89c8a58999a1c 759 Gene3D G3DSA:3.40.50.1820 499 759 1.5E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS12795 31835f90db2bd1486b5f4fcc000d9f1e 129 Pfam PF01042 Endoribonuclease L-PSP 10 123 1.9E-20 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS12795 31835f90db2bd1486b5f4fcc000d9f1e 129 Gene3D G3DSA:3.30.1330.40 1 126 2.1E-29 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS12795 31835f90db2bd1486b5f4fcc000d9f1e 129 SUPERFAMILY SSF55298 5 123 2.2E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS16430 18bfa8538485e8e2317750198431ee44 87 Pfam PF02467 Transcription factor WhiB 19 82 6.3E-27 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS16430 18bfa8538485e8e2317750198431ee44 87 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 87 18.896 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS23375 1f08b7a31b59ee6d0fdd1167a30e5033 260 Pfam PF01614 Bacterial transcriptional regulator 181 230 7.0E-5 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS23375 1f08b7a31b59ee6d0fdd1167a30e5033 260 Gene3D G3DSA:3.30.450.40 86 260 4.3E-17 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS23375 1f08b7a31b59ee6d0fdd1167a30e5033 260 SUPERFAMILY SSF46785 24 87 1.47E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23375 1f08b7a31b59ee6d0fdd1167a30e5033 260 SUPERFAMILY SSF55781 82 248 7.85E-14 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS23375 1f08b7a31b59ee6d0fdd1167a30e5033 260 SMART SM00346 19 106 7.7E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS23375 1f08b7a31b59ee6d0fdd1167a30e5033 260 Pfam PF09339 IclR helix-turn-helix domain 26 70 6.1E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS23375 1f08b7a31b59ee6d0fdd1167a30e5033 260 Gene3D G3DSA:1.10.10.10 15 85 2.9E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS41035 49a2e136bd90d389be1dea5ba8d59b6b 341 SUPERFAMILY SSF103481 107 206 2.09E-5 T 28-03-2018 SMD44_RS41035 49a2e136bd90d389be1dea5ba8d59b6b 341 Pfam PF00892 EamA-like transporter family 71 206 2.1E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS20005 f893dfb59d33db712d3d3c3861fee101 331 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS20005 f893dfb59d33db712d3d3c3861fee101 331 SUPERFAMILY SSF52540 3 223 1.58E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20005 f893dfb59d33db712d3d3c3861fee101 331 SMART SM00382 31 217 2.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS20005 f893dfb59d33db712d3d3c3861fee101 331 Pfam PF00005 ABC transporter 23 160 3.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS20005 f893dfb59d33db712d3d3c3861fee101 331 Gene3D G3DSA:3.40.50.300 2 330 9.0E-64 T 28-03-2018 SMD44_RS04310 eb32490ce00f9baa1bc33fe168dfbbdd 184 SUPERFAMILY SSF53098 6 175 5.94E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS04310 eb32490ce00f9baa1bc33fe168dfbbdd 184 Gene3D G3DSA:3.30.420.10 2 184 1.7E-4 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS04310 eb32490ce00f9baa1bc33fe168dfbbdd 184 Pfam PF16473 3' exoribonuclease, RNase T-like 6 172 3.1E-17 T 28-03-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain SMD44_RS28690 f59e31a835d0faa801b4889c8170101a 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 6.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28690 f59e31a835d0faa801b4889c8170101a 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 6.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS28690 f59e31a835d0faa801b4889c8170101a 243 Gene3D G3DSA:1.10.357.10 4 239 1.6E-39 T 28-03-2018 SMD44_RS28690 f59e31a835d0faa801b4889c8170101a 243 SUPERFAMILY SSF46689 11 84 5.99E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS28690 f59e31a835d0faa801b4889c8170101a 243 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 70 1.2E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18320 756fd441e4d7af5f6d0cde4b609cdad9 329 SUPERFAMILY SSF103481 80 172 8.89E-6 T 28-03-2018 SMD44_RS18320 756fd441e4d7af5f6d0cde4b609cdad9 329 SUPERFAMILY SSF103481 235 317 1.44E-10 T 28-03-2018 SMD44_RS18320 756fd441e4d7af5f6d0cde4b609cdad9 329 Pfam PF00892 EamA-like transporter family 184 313 4.5E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 Gene3D G3DSA:1.10.1660.10 1 54 1.1E-20 T 28-03-2018 SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 SUPERFAMILY SSF46955 1 114 7.69E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.1E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.1E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 6.1E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 SMART SM00422 1 69 1.2E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 Gene3D G3DSA:1.10.1660.10 55 125 1.3E-11 T 28-03-2018 SMD44_RS02175 6ebf68c5fff39de35567533dfb237680 126 Pfam PF13411 MerR HTH family regulatory protein 3 67 2.0E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 SUPERFAMILY SSF54631 325 459 4.8E-15 T 28-03-2018 SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 Pfam PF00571 CBS domain 340 395 4.6E-5 T 28-03-2018 IPR000644 CBS domain SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 Pfam PF00571 CBS domain 410 458 0.0029 T 28-03-2018 IPR000644 CBS domain SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 Gene3D G3DSA:3.40.50.1100 142 316 4.1E-52 T 28-03-2018 SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 SMART SM00116 340 396 0.23 T 28-03-2018 IPR000644 CBS domain SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 SMART SM00116 413 458 17.0 T 28-03-2018 IPR000644 CBS domain SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 3.4E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 458 1.8E-212 T 28-03-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 Gene3D G3DSA:3.10.580.10 318 463 2.0E-20 T 28-03-2018 SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 SUPERFAMILY SSF53686 3 317 3.54E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 Gene3D G3DSA:3.40.50.1100 41 141 1.5E-37 T 28-03-2018 SMD44_RS16705 8fa1ec30563f96e781d5aab438308168 463 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SMD44_RS27465 b1d29a72f2ebb3c714407947664cd33f 175 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 1.3E-14 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS27465 b1d29a72f2ebb3c714407947664cd33f 175 SUPERFAMILY SSF46785 3 167 1.17E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27465 b1d29a72f2ebb3c714407947664cd33f 175 Gene3D G3DSA:1.10.10.10 1 92 7.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19600 573c6bbb2d43cc5604a0c01a3dc93a5f 455 Pfam PF13367 Protease prsW family 90 289 1.5E-50 T 28-03-2018 IPR026898 Protease PrsW GO:0008233 SMD44_RS28460 b414166daa4bf7ef5db2bb3624303032 199 Gene3D G3DSA:3.40.630.30 2 198 7.0E-34 T 28-03-2018 SMD44_RS28460 b414166daa4bf7ef5db2bb3624303032 199 SUPERFAMILY SSF55729 5 77 1.46E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS28460 b414166daa4bf7ef5db2bb3624303032 199 SUPERFAMILY SSF55729 109 184 1.46E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS28460 b414166daa4bf7ef5db2bb3624303032 199 Pfam PF00583 Acetyltransferase (GNAT) family 105 174 2.4E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS13465 fe3c37ffca953ca1fd743cabc91ff7dc 521 SUPERFAMILY SSF53474 195 249 5.3E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS13465 fe3c37ffca953ca1fd743cabc91ff7dc 521 SUPERFAMILY SSF53474 340 468 5.3E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS13465 fe3c37ffca953ca1fd743cabc91ff7dc 521 SUPERFAMILY SSF53474 93 153 5.3E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS13465 fe3c37ffca953ca1fd743cabc91ff7dc 521 Gene3D G3DSA:3.40.50.1820 18 480 1.9E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS13465 fe3c37ffca953ca1fd743cabc91ff7dc 521 Pfam PF00561 alpha/beta hydrolase fold 103 463 1.3E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS23380 df62e746cfda3758cdc0e326593d2242 520 Pfam PF00501 AMP-binding enzyme 14 416 1.2E-74 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS23380 df62e746cfda3758cdc0e326593d2242 520 Gene3D G3DSA:2.30.38.10 324 409 2.5E-18 T 28-03-2018 SMD44_RS23380 df62e746cfda3758cdc0e326593d2242 520 SUPERFAMILY SSF56801 13 513 5.23E-128 T 28-03-2018 SMD44_RS23380 df62e746cfda3758cdc0e326593d2242 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 503 9.8E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS23380 df62e746cfda3758cdc0e326593d2242 520 Gene3D G3DSA:3.40.50.980 10 171 2.7E-36 T 28-03-2018 SMD44_RS23380 df62e746cfda3758cdc0e326593d2242 520 Gene3D G3DSA:3.40.50.980 172 323 2.1E-32 T 28-03-2018 SMD44_RS23380 df62e746cfda3758cdc0e326593d2242 520 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS23380 df62e746cfda3758cdc0e326593d2242 520 Gene3D G3DSA:3.30.300.30 411 517 4.9E-29 T 28-03-2018 SMD44_RS06135 9844ad6b68809c7853773b5c6c068cbc 222 PRINTS PR01399 Enterobactin synthetase component D signature 67 85 1.7E-25 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD44_RS06135 9844ad6b68809c7853773b5c6c068cbc 222 PRINTS PR01399 Enterobactin synthetase component D signature 37 57 1.7E-25 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD44_RS06135 9844ad6b68809c7853773b5c6c068cbc 222 PRINTS PR01399 Enterobactin synthetase component D signature 145 161 1.7E-25 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD44_RS06135 9844ad6b68809c7853773b5c6c068cbc 222 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 101 185 7.7E-11 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS06135 9844ad6b68809c7853773b5c6c068cbc 222 SUPERFAMILY SSF56214 99 215 2.79E-12 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS06135 9844ad6b68809c7853773b5c6c068cbc 222 Gene3D G3DSA:3.90.470.20 9 109 7.7E-17 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS06135 9844ad6b68809c7853773b5c6c068cbc 222 Gene3D G3DSA:3.90.470.20 110 217 3.9E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS01085 ab2eec4df116cc48749c6be9f3d68a18 340 Pfam PF00268 Ribonucleotide reductase, small chain 29 299 3.1E-78 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS01085 ab2eec4df116cc48749c6be9f3d68a18 340 SUPERFAMILY SSF47240 26 340 6.39E-92 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS01085 ab2eec4df116cc48749c6be9f3d68a18 340 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 27 340 2.4E-129 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD44_RS01085 ab2eec4df116cc48749c6be9f3d68a18 340 Gene3D G3DSA:1.10.620.20 14 313 1.7E-64 T 28-03-2018 SMD44_RS26310 9e23fcf21e00cf58a9e7ba0d3d6d616b 146 SUPERFAMILY SSF55874 45 136 8.66E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26310 9e23fcf21e00cf58a9e7ba0d3d6d616b 146 Gene3D G3DSA:3.30.565.10 14 143 2.1E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26310 9e23fcf21e00cf58a9e7ba0d3d6d616b 146 Pfam PF13581 Histidine kinase-like ATPase domain 24 123 1.5E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS35165 238cdd61b7fa86997459d72ea061acba 486 Pfam PF00916 Sulfate permease family 9 375 2.6E-59 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMD44_RS24390 da8b933b529fdac33a230d2baf6a5a9a 169 SUPERFAMILY SSF55961 11 162 1.63E-28 T 28-03-2018 SMD44_RS24390 da8b933b529fdac33a230d2baf6a5a9a 169 Gene3D G3DSA:3.30.530.20 1 169 6.8E-27 T 28-03-2018 IPR023393 START-like domain SMD44_RS24390 da8b933b529fdac33a230d2baf6a5a9a 169 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 30 146 4.2E-11 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMD44_RS22160 4e60baf3a2a454f4f41c46b0861bfbe2 148 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 19 135 1.2E-21 T 28-03-2018 IPR018727 Protein of unknown function DUF2267 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 Gene3D G3DSA:3.40.50.2300 4 132 4.3E-38 T 28-03-2018 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 SUPERFAMILY SSF46894 166 227 1.84E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 186 8.5E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 214 8.5E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 202 8.5E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 Pfam PF00072 Response regulator receiver domain 7 121 3.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 SMART SM00421 169 226 2.2E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 SUPERFAMILY SSF52172 5 130 3.13E-33 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 SMART SM00448 5 121 3.7E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 Gene3D G3DSA:1.10.10.10 133 231 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01370 0a42a84afed0792b11a9a95af899e9b3 261 Pfam PF00196 Bacterial regulatory proteins, luxR family 172 225 4.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS27080 66ec7dbf46309cc9407398264df87f77 266 Pfam PF00561 alpha/beta hydrolase fold 22 248 6.5E-26 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS27080 66ec7dbf46309cc9407398264df87f77 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 1.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS27080 66ec7dbf46309cc9407398264df87f77 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS27080 66ec7dbf46309cc9407398264df87f77 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 1.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS27080 66ec7dbf46309cc9407398264df87f77 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 1.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS27080 66ec7dbf46309cc9407398264df87f77 266 Gene3D G3DSA:3.40.50.1820 1 266 4.8E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27080 66ec7dbf46309cc9407398264df87f77 266 SUPERFAMILY SSF53474 8 262 9.13E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS03100 fdc59a4d83cb5b58229d0c7fa7402eb7 366 Pfam PF00296 Luciferase-like monooxygenase 22 319 2.3E-52 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS03100 fdc59a4d83cb5b58229d0c7fa7402eb7 366 SUPERFAMILY SSF51679 27 346 5.1E-67 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS03100 fdc59a4d83cb5b58229d0c7fa7402eb7 366 Gene3D G3DSA:3.20.20.30 1 350 6.6E-62 T 28-03-2018 SMD44_RS29580 01afee60533563fe6792e3bdda3e08fe 254 SUPERFAMILY SSF88713 57 253 2.47E-36 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS29580 01afee60533563fe6792e3bdda3e08fe 254 Pfam PF01522 Polysaccharide deacetylase 64 184 3.6E-15 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS29580 01afee60533563fe6792e3bdda3e08fe 254 Gene3D G3DSA:3.20.20.370 54 254 3.3E-35 T 28-03-2018 SMD44_RS14825 08d792d56b5996b2ef12cab4f37af183 103 SUPERFAMILY SSF55811 22 98 4.47E-10 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS14825 08d792d56b5996b2ef12cab4f37af183 103 Gene3D G3DSA:3.90.79.10 11 102 8.0E-8 T 28-03-2018 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 Pfam PF13549 ATP-grasp domain 520 736 4.7E-62 T 28-03-2018 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 SUPERFAMILY SSF51735 53 181 4.89E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 Gene3D G3DSA:3.30.470.20 610 741 2.8E-29 T 28-03-2018 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 Gene3D G3DSA:3.30.1490.20 547 609 2.1E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 SUPERFAMILY SSF52210 338 495 4.32E-25 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 SUPERFAMILY SSF52210 192 334 3.79E-32 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 SUPERFAMILY SSF56059 528 739 2.16E-40 T 28-03-2018 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 Pfam PF13380 CoA binding domain 61 181 3.7E-15 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 Gene3D G3DSA:3.40.50.720 52 176 5.4E-31 T 28-03-2018 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 Gene3D G3DSA:3.40.50.261 336 502 3.4E-24 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 SMART SM00881 56 151 6.7E-19 T 28-03-2018 IPR003781 CoA-binding GO:0048037 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 Gene3D G3DSA:3.40.50.261 177 335 2.4E-26 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD44_RS17995 7a7919cd37544fdc8aa40f68df7536f5 741 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 198 332 5.2E-44 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 SMART SM00331 353 570 1.9E-38 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 379 571 2.5E-54 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 Gene3D G3DSA:3.30.565.10 575 698 9.9E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 SUPERFAMILY SSF81606 367 571 1.8E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 Gene3D G3DSA:3.60.40.10 326 573 1.5E-44 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 SUPERFAMILY SSF55874 605 694 1.49E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 SUPERFAMILY SSF55781 275 339 3.45E-7 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 Pfam PF13581 Histidine kinase-like ATPase domain 591 678 3.2E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27480 b0f4b5bc5b6785ee3dec266a1be71580 698 Gene3D G3DSA:3.30.450.40 130 325 9.0E-21 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS02010 b05c3ff3b44d99910fa200a4c7cdc8c7 286 SUPERFAMILY SSF56219 71 286 2.09E-27 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS02010 b05c3ff3b44d99910fa200a4c7cdc8c7 286 Gene3D G3DSA:3.60.10.10 64 285 1.6E-24 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS02010 b05c3ff3b44d99910fa200a4c7cdc8c7 286 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 88 277 1.1E-11 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS16945 c57d1fb9ccb126a0de0e6abcf12174ed 328 SUPERFAMILY SSF53271 77 313 6.66E-62 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS16945 c57d1fb9ccb126a0de0e6abcf12174ed 328 SMART SM01400 12 128 1.1E-70 T 28-03-2018 SMD44_RS16945 c57d1fb9ccb126a0de0e6abcf12174ed 328 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 322 46.341 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMD44_RS16945 c57d1fb9ccb126a0de0e6abcf12174ed 328 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 1.4E-44 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMD44_RS16945 c57d1fb9ccb126a0de0e6abcf12174ed 328 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 321 4.6E-24 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMD44_RS16945 c57d1fb9ccb126a0de0e6abcf12174ed 328 Gene3D G3DSA:3.40.50.2020 165 298 4.4E-37 T 28-03-2018 SMD44_RS16945 c57d1fb9ccb126a0de0e6abcf12174ed 328 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 12 322 1.1E-112 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMD44_RS16945 c57d1fb9ccb126a0de0e6abcf12174ed 328 Gene3D G3DSA:3.40.50.2020 9 164 1.7E-59 T 28-03-2018 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 SMART SM00530 12 68 3.3E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 SMART SM00028 209 242 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 SMART SM00028 257 290 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 SMART SM00028 169 202 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 SMART SM00028 341 374 1.9 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 SUPERFAMILY SSF47413 7 70 8.04E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 Gene3D G3DSA:1.25.40.10 223 249 0.27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 Gene3D G3DSA:1.25.40.10 85 222 0.006 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 Gene3D G3DSA:1.10.260.40 1 84 2.2E-15 T 28-03-2018 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 Pfam PF13560 Helix-turn-helix domain 9 66 4.8E-14 T 28-03-2018 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 SUPERFAMILY SSF48452 339 376 7.32E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 SUPERFAMILY SSF48452 169 294 7.32E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS05705 b0cdd9a58922f3093d22c17cd97e6b11 411 Gene3D G3DSA:1.25.40.10 250 383 7.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS42735 86ae77b26fb789763931abb93f0374e8 369 SUPERFAMILY SSF53383 27 361 2.11E-68 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS42735 86ae77b26fb789763931abb93f0374e8 369 Gene3D G3DSA:3.40.640.10 17 237 2.5E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS42735 86ae77b26fb789763931abb93f0374e8 369 PIRSF PIRSF000390 19 366 4.5E-68 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD44_RS42735 86ae77b26fb789763931abb93f0374e8 369 Gene3D G3DSA:3.90.1150.10 238 366 6.1E-10 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS42735 86ae77b26fb789763931abb93f0374e8 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 30 345 4.1E-71 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD44_RS36075 2f381dcd65ba0a7e632ad7b6b3b469f0 105 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 102 4.7E-13 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD SMD44_RS19960 b89d4251f9b00a737f1d2a4d12de7f45 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 87 2.9E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19960 b89d4251f9b00a737f1d2a4d12de7f45 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 57 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19960 b89d4251f9b00a737f1d2a4d12de7f45 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19960 b89d4251f9b00a737f1d2a4d12de7f45 237 Gene3D G3DSA:1.10.357.10 86 232 2.1E-20 T 28-03-2018 SMD44_RS19960 b89d4251f9b00a737f1d2a4d12de7f45 237 Gene3D G3DSA:1.10.10.60 22 85 8.7E-21 T 28-03-2018 SMD44_RS19960 b89d4251f9b00a737f1d2a4d12de7f45 237 SUPERFAMILY SSF46689 32 108 1.28E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS07840 38db7f5c8bfb545ea9c4e03062da4643 191 SUPERFAMILY SSF53254 15 186 5.78E-28 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS07840 38db7f5c8bfb545ea9c4e03062da4643 191 Gene3D G3DSA:3.40.50.1240 5 187 2.4E-18 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS07840 38db7f5c8bfb545ea9c4e03062da4643 191 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 23 185 3.9E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS10495 f48aabe30a67069ead5649cb10f38aea 276 SUPERFAMILY SSF53335 27 255 1.74E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS10495 f48aabe30a67069ead5649cb10f38aea 276 Gene3D G3DSA:3.40.50.150 19 232 2.9E-31 T 28-03-2018 SMD44_RS10495 f48aabe30a67069ead5649cb10f38aea 276 Pfam PF08241 Methyltransferase domain 79 175 3.3E-19 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 SUPERFAMILY SSF48613 10 219 2.52E-59 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 PRINTS PR00088 Haem oxygenase signature 167 188 7.7E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 PRINTS PR00088 Haem oxygenase signature 70 95 7.7E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 PRINTS PR00088 Haem oxygenase signature 10 35 7.7E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 PRINTS PR00088 Haem oxygenase signature 45 70 7.7E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 PRINTS PR00088 Haem oxygenase signature 123 144 7.7E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 PIRSF PIRSF000343 1 225 1.5E-65 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 Gene3D G3DSA:1.20.910.10 2 222 6.2E-67 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS12030 f57344050d31e1751b45bc154d082004 225 Pfam PF01126 Heme oxygenase 10 216 9.9E-63 T 28-03-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS16660 37246f8a012389e04df6668081855f74 136 Gene3D G3DSA:3.30.450.30 2 135 3.1E-31 T 28-03-2018 SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 Pfam PF12802 MarR family 74 133 1.5E-12 T 28-03-2018 SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 125 2.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 159 179 2.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 129 145 2.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 2.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 SUPERFAMILY SSF46785 48 180 4.3E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 SMART SM00347 68 169 3.7E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 ProSitePatterns PS01117 MarR-type HTH domain signature. 108 142 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS26525 d7bb95f66446de154002ef54cf4da836 192 Gene3D G3DSA:1.10.10.10 25 186 3.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24255 ae4e62814cbde65c4cbba301bf3527bd 525 Pfam PF10935 Protein of unknown function (DUF2637) 13 166 1.3E-41 T 28-03-2018 IPR021235 Protein of unknown function DUF2637 SMD44_RS34510 7758e3623f117f81d97f6656c53c2c57 112 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 3 106 20.305 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMD44_RS34510 7758e3623f117f81d97f6656c53c2c57 112 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 104 3.9E-23 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMD44_RS34510 7758e3623f117f81d97f6656c53c2c57 112 SUPERFAMILY SSF55248 4 106 1.31E-21 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMD44_RS34510 7758e3623f117f81d97f6656c53c2c57 112 Gene3D G3DSA:3.30.1360.20 13 110 3.6E-25 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 Gene3D G3DSA:1.10.1660.10 59 140 1.4E-6 T 28-03-2018 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 8.1E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 8.1E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 8.1E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 Gene3D G3DSA:1.10.1660.10 1 58 6.5E-22 T 28-03-2018 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 Gene3D G3DSA:1.10.490.50 162 251 1.3E-10 T 28-03-2018 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 Pfam PF13411 MerR HTH family regulatory protein 5 71 5.9E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 Pfam PF07739 TipAS antibiotic-recognition domain 149 247 5.6E-11 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 SUPERFAMILY SSF89082 167 249 2.62E-10 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 SMART SM00422 3 72 1.9E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS41860 b6b2d4257d1963132050e658f092725f 253 SUPERFAMILY SSF46955 4 107 4.4E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS00890 57c39508e6dc2959b64d417105f1b1b7 251 SUPERFAMILY SSF48498 98 233 3.56E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS00890 57c39508e6dc2959b64d417105f1b1b7 251 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00890 57c39508e6dc2959b64d417105f1b1b7 251 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00890 57c39508e6dc2959b64d417105f1b1b7 251 SUPERFAMILY SSF46689 14 88 9.98E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00890 57c39508e6dc2959b64d417105f1b1b7 251 Gene3D G3DSA:1.10.10.60 1 46 8.9E-15 T 28-03-2018 SMD44_RS00890 57c39508e6dc2959b64d417105f1b1b7 251 Gene3D G3DSA:1.10.260.40 47 78 2.2E-12 T 28-03-2018 SMD44_RS00890 57c39508e6dc2959b64d417105f1b1b7 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 6.0E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00890 57c39508e6dc2959b64d417105f1b1b7 251 Gene3D G3DSA:1.10.357.10 79 238 2.8E-27 T 28-03-2018 SMD44_RS38730 7dbfac300b55206598a384832cfe976d 122 SUPERFAMILY SSF54427 1 116 4.9E-21 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS38730 7dbfac300b55206598a384832cfe976d 122 Gene3D G3DSA:3.10.450.50 3 122 3.5E-21 T 28-03-2018 SMD44_RS38730 7dbfac300b55206598a384832cfe976d 122 Pfam PF12680 SnoaL-like domain 10 109 1.2E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS32340 13944169683c93ebd6f751b55d439b68 160 Pfam PF14102 Capsule biosynthesis CapC 17 133 1.5E-32 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMD44_RS32340 13944169683c93ebd6f751b55d439b68 160 PRINTS PR01759 Capsule biosynthesis protein CapC signature 25 42 5.2E-6 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMD44_RS32340 13944169683c93ebd6f751b55d439b68 160 PRINTS PR01759 Capsule biosynthesis protein CapC signature 71 85 5.2E-6 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMD44_RS23535 0e5c3346f4bba0cb8a71ad9182a857b5 282 SUPERFAMILY SSF56317 1 268 2.22E-60 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS23535 0e5c3346f4bba0cb8a71ad9182a857b5 282 Gene3D G3DSA:3.60.110.10 1 275 1.3E-61 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS23535 0e5c3346f4bba0cb8a71ad9182a857b5 282 Pfam PF00795 Carbon-nitrogen hydrolase 2 254 4.1E-30 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS15185 1e4bc34b993de1efb0835517cedac040 467 SUPERFAMILY SSF75304 1 453 7.46E-134 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS15185 1e4bc34b993de1efb0835517cedac040 467 Pfam PF01425 Amidase 25 447 1.0E-100 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS15185 1e4bc34b993de1efb0835517cedac040 467 ProSitePatterns PS00571 Amidases signature. 154 185 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMD44_RS15185 1e4bc34b993de1efb0835517cedac040 467 Gene3D G3DSA:3.90.1300.10 1 465 4.2E-136 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD44_RS09265 e00aed3784722861edd804b050e8e339 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 39 170 1.8E-40 T 28-03-2018 IPR005247 YbhB/YbcL SMD44_RS09265 e00aed3784722861edd804b050e8e339 179 Gene3D G3DSA:3.90.280.10 6 175 8.7E-47 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS09265 e00aed3784722861edd804b050e8e339 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 1.8E-36 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS09265 e00aed3784722861edd804b050e8e339 179 SUPERFAMILY SSF49777 20 174 1.28E-48 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMD44_RS09140 8fc87f42fb8981007c512237b1341925 544 Gene3D G3DSA:1.10.10.60 465 517 8.2E-9 T 28-03-2018 SMD44_RS09140 8fc87f42fb8981007c512237b1341925 544 Pfam PF07905 Purine catabolism regulatory protein-like family 15 135 2.2E-37 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain SMD44_RS09140 8fc87f42fb8981007c512237b1341925 544 Pfam PF13556 PucR C-terminal helix-turn-helix domain 481 539 2.1E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS09140 8fc87f42fb8981007c512237b1341925 544 Gene3D G3DSA:3.40.50.2300 18 161 1.8E-5 T 28-03-2018 SMD44_RS37985 2458f32203dc96485256e82ce4022cfb 226 Pfam PF13353 4Fe-4S single cluster domain 29 162 1.1E-28 T 28-03-2018 SMD44_RS37985 2458f32203dc96485256e82ce4022cfb 226 Pfam PF04055 Radical SAM superfamily 37 132 2.8E-7 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS37985 2458f32203dc96485256e82ce4022cfb 226 Gene3D G3DSA:3.20.20.70 24 216 1.2E-10 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS37985 2458f32203dc96485256e82ce4022cfb 226 SUPERFAMILY SSF102114 39 107 2.35E-7 T 28-03-2018 SMD44_RS27720 6b3318e39bb63e72a6d0fce9bbe10982 307 SUPERFAMILY SSF161098 91 288 9.16E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS27720 6b3318e39bb63e72a6d0fce9bbe10982 307 Gene3D G3DSA:1.10.3720.10 2 294 7.9E-45 T 28-03-2018 SMD44_RS27720 6b3318e39bb63e72a6d0fce9bbe10982 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 6.8E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS37085 9da7bba3eac4caa9611738a65ce17a92 279 SMART SM00418 34 114 1.5E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS37085 9da7bba3eac4caa9611738a65ce17a92 279 SUPERFAMILY SSF46785 30 107 2.12E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37085 9da7bba3eac4caa9611738a65ce17a92 279 Pfam PF12840 Helix-turn-helix domain 35 88 2.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37085 9da7bba3eac4caa9611738a65ce17a92 279 Gene3D G3DSA:1.10.10.10 4 190 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20860 21af7906aacd2c7a7c66d08c152a6a5d 145 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 1.3E-32 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD44_RS42505 bfa16086940a56b8478ff20aad6fbdad 410 Pfam PF02378 Phosphotransferase system, EIIC 33 332 1.3E-40 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMD44_RS27840 58c8d002f4feb6a45f01239f315a9e10 196 Pfam PF03352 Methyladenine glycosylase 17 189 2.5E-67 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 SMD44_RS27840 58c8d002f4feb6a45f01239f315a9e10 196 Gene3D G3DSA:1.10.340.30 13 191 2.1E-75 T 28-03-2018 SMD44_RS27840 58c8d002f4feb6a45f01239f315a9e10 196 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 14 190 1.6E-72 T 28-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 SMD44_RS27840 58c8d002f4feb6a45f01239f315a9e10 196 SUPERFAMILY SSF48150 13 191 8.63E-69 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD44_RS29110 a9f85dee6ee50177c81afe9d9ec9b664 252 Gene3D G3DSA:3.90.1560.10 18 252 2.0E-61 T 28-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 SMD44_RS29110 a9f85dee6ee50177c81afe9d9ec9b664 252 SUPERFAMILY SSF142823 12 248 1.44E-38 T 28-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 SMD44_RS29110 a9f85dee6ee50177c81afe9d9ec9b664 252 Pfam PF04029 2-phosphosulpholactate phosphatase 31 244 8.6E-21 T 28-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 SMD44_RS16325 6eeca6debbe8975780363af3c89fa86f 327 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 1.6E-64 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SMD44_RS16325 6eeca6debbe8975780363af3c89fa86f 327 SMART SM00382 46 187 0.0032 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16325 6eeca6debbe8975780363af3c89fa86f 327 SUPERFAMILY SSF52540 19 302 9.07E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16325 6eeca6debbe8975780363af3c89fa86f 327 Gene3D G3DSA:1.10.8.300 215 323 1.5E-35 T 28-03-2018 SMD44_RS16325 6eeca6debbe8975780363af3c89fa86f 327 Gene3D G3DSA:3.40.50.300 30 196 2.4E-27 T 28-03-2018 SMD44_RS16325 6eeca6debbe8975780363af3c89fa86f 327 PIRSF PIRSF002849 2 327 5.8E-133 T 28-03-2018 SMD44_RS01645 4506d3c73aead4b7f9bfb6011518b504 391 SUPERFAMILY SSF103473 3 373 4.32E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS01645 4506d3c73aead4b7f9bfb6011518b504 391 Gene3D G3DSA:1.20.1250.20 1 183 3.9E-26 T 28-03-2018 SMD44_RS01645 4506d3c73aead4b7f9bfb6011518b504 391 Pfam PF07690 Major Facilitator Superfamily 203 381 5.2E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS01645 4506d3c73aead4b7f9bfb6011518b504 391 Pfam PF07690 Major Facilitator Superfamily 8 175 6.2E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS01645 4506d3c73aead4b7f9bfb6011518b504 391 Gene3D G3DSA:1.20.1250.20 189 381 2.5E-18 T 28-03-2018 SMD44_RS28920 45601b9b12a2904116fbb015a4f9bcd4 399 Pfam PF07730 Histidine kinase 185 248 2.3E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS28920 45601b9b12a2904116fbb015a4f9bcd4 399 Gene3D G3DSA:3.30.565.10 256 397 5.8E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28920 45601b9b12a2904116fbb015a4f9bcd4 399 SUPERFAMILY SSF55874 274 367 5.85E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS10625 ccffa57f3984bebea8c56a41ee51688d 388 Pfam PF07730 Histidine kinase 184 248 1.1E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS10625 ccffa57f3984bebea8c56a41ee51688d 388 Gene3D G3DSA:3.30.565.10 250 387 6.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS10625 ccffa57f3984bebea8c56a41ee51688d 388 SUPERFAMILY SSF55874 288 382 9.64E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS31455 4dbcf504e2b5763cdc0e331aeab86a39 210 Gene3D G3DSA:1.10.10.60 1 74 3.1E-14 T 28-03-2018 SMD44_RS31455 4dbcf504e2b5763cdc0e331aeab86a39 210 SUPERFAMILY SSF48498 88 205 3.89E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS31455 4dbcf504e2b5763cdc0e331aeab86a39 210 SUPERFAMILY SSF46689 21 82 1.25E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS31455 4dbcf504e2b5763cdc0e331aeab86a39 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 74 4.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS31455 4dbcf504e2b5763cdc0e331aeab86a39 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 87 195 5.1E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS31455 4dbcf504e2b5763cdc0e331aeab86a39 210 Gene3D G3DSA:1.10.357.10 75 210 8.4E-24 T 28-03-2018 SMD44_RS16140 26c40734d63e1a68a118c82fd6202bfa 328 Gene3D G3DSA:3.40.50.720 1 169 9.6E-32 T 28-03-2018 SMD44_RS16140 26c40734d63e1a68a118c82fd6202bfa 328 Gene3D G3DSA:3.90.25.10 170 328 6.4E-33 T 28-03-2018 SMD44_RS16140 26c40734d63e1a68a118c82fd6202bfa 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 320 2.8E-99 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 SMD44_RS16140 26c40734d63e1a68a118c82fd6202bfa 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 242 3.9E-50 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS16140 26c40734d63e1a68a118c82fd6202bfa 328 SUPERFAMILY SSF51735 1 317 3.84E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31485 d2d4b49fc15f6ac0213f6a1b25a88b39 233 Gene3D G3DSA:3.30.420.10 3 228 4.3E-60 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS31485 d2d4b49fc15f6ac0213f6a1b25a88b39 233 Hamap MF_00052_B Ribonuclease HII [rnhB]. 22 202 35.359 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 SMD44_RS31485 d2d4b49fc15f6ac0213f6a1b25a88b39 233 Pfam PF01351 Ribonuclease HII 24 200 7.4E-34 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain SMD44_RS31485 d2d4b49fc15f6ac0213f6a1b25a88b39 233 SUPERFAMILY SSF53098 17 217 1.4E-56 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS42680 07bb613e94f2a7a109b677b1d96a916c 646 SUPERFAMILY SSF90123 72 367 4.19E-12 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS42680 07bb613e94f2a7a109b677b1d96a916c 646 Pfam PF00005 ABC transporter 421 572 1.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS42680 07bb613e94f2a7a109b677b1d96a916c 646 Gene3D G3DSA:1.20.1560.10 69 388 1.3E-8 T 28-03-2018 SMD44_RS42680 07bb613e94f2a7a109b677b1d96a916c 646 SMART SM00382 428 618 1.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS42680 07bb613e94f2a7a109b677b1d96a916c 646 Gene3D G3DSA:3.40.50.300 389 644 5.5E-63 T 28-03-2018 SMD44_RS42680 07bb613e94f2a7a109b677b1d96a916c 646 SUPERFAMILY SSF52540 397 633 9.69E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PRINTS PR00733 Glycosyl hydrolase family 6 signature 188 201 5.4E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PRINTS PR00733 Glycosyl hydrolase family 6 signature 63 82 5.4E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PRINTS PR00733 Glycosyl hydrolase family 6 signature 267 287 5.4E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PRINTS PR00733 Glycosyl hydrolase family 6 signature 291 305 5.4E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PRINTS PR00733 Glycosyl hydrolase family 6 signature 103 116 5.4E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PRINTS PR00733 Glycosyl hydrolase family 6 signature 131 146 5.4E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PRINTS PR00733 Glycosyl hydrolase family 6 signature 218 228 5.4E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PRINTS PR00733 Glycosyl hydrolase family 6 signature 248 261 5.4E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 Gene3D G3DSA:3.20.20.40 39 328 6.5E-100 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 SUPERFAMILY SSF51989 34 327 3.79E-89 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 Pfam PF01341 Glycosyl hydrolases family 6 50 310 3.3E-82 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS15340 0068a04dab2a9f5cf8f9c31d8d29acca 329 PIRSF PIRSF001100 8 329 8.2E-92 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS23670 19f8e85436c654042dc1fc6d9f855887 550 Pfam PF06738 Putative threonine/serine exporter 128 372 2.5E-61 T 28-03-2018 IPR010619 Putative threonine/serine exporter SMD44_RS23670 19f8e85436c654042dc1fc6d9f855887 550 Pfam PF12821 Threonine/Serine exporter, ThrE 395 520 5.6E-15 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE SMD44_RS19490 cad1adaf7b8ce37ea15af51de3cd38ef 476 Pfam PF12846 AAA-like domain 69 350 1.1E-14 T 28-03-2018 SMD44_RS19490 cad1adaf7b8ce37ea15af51de3cd38ef 476 Gene3D G3DSA:3.40.50.300 51 451 7.8E-15 T 28-03-2018 SMD44_RS19490 cad1adaf7b8ce37ea15af51de3cd38ef 476 SUPERFAMILY SSF52540 40 423 5.04E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14240 f8afd55ad20417e1bd395d3c33449722 464 ProSitePatterns PS00218 Amino acid permeases signature. 47 77 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD44_RS14240 f8afd55ad20417e1bd395d3c33449722 464 PIRSF PIRSF006060 2 462 4.6E-73 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS14240 f8afd55ad20417e1bd395d3c33449722 464 Pfam PF00324 Amino acid permease 22 446 1.7E-111 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD44_RS17620 74a2c62a2e18109a792cab562fa025ed 406 SUPERFAMILY SSF56601 4 265 1.46E-37 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS17620 74a2c62a2e18109a792cab562fa025ed 406 Gene3D G3DSA:3.40.710.10 18 341 1.1E-41 T 28-03-2018 SMD44_RS17620 74a2c62a2e18109a792cab562fa025ed 406 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 72 264 1.2E-29 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD44_RS17620 74a2c62a2e18109a792cab562fa025ed 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 79 90 3.8E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS17620 74a2c62a2e18109a792cab562fa025ed 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 139 156 3.8E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS17620 74a2c62a2e18109a792cab562fa025ed 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 167 180 3.8E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD44_RS22385 4c5c1faf80b18ca2f8de9fb4413d16ea 61 Pfam PF12728 Helix-turn-helix domain 4 52 9.2E-8 T 28-03-2018 SMD44_RS22385 4c5c1faf80b18ca2f8de9fb4413d16ea 61 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 1.6E-10 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD44_RS22385 4c5c1faf80b18ca2f8de9fb4413d16ea 61 Gene3D G3DSA:1.10.10.10 4 61 6.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS43090 946637e6a25097bddcb0918a4a8a00a4 465 Pfam PF00437 Type II/IV secretion system protein 94 359 2.5E-36 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMD44_RS43090 946637e6a25097bddcb0918a4a8a00a4 465 Gene3D G3DSA:3.40.50.300 187 407 1.1E-10 T 28-03-2018 SMD44_RS43090 946637e6a25097bddcb0918a4a8a00a4 465 SUPERFAMILY SSF52540 79 378 1.12E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43090 946637e6a25097bddcb0918a4a8a00a4 465 Gene3D G3DSA:3.30.450.90 86 186 2.9E-23 T 28-03-2018 SMD44_RS17880 c78b82549dd50341c7ecde606a129491 425 Gene3D G3DSA:3.20.20.140 22 415 7.2E-62 T 28-03-2018 SMD44_RS17880 c78b82549dd50341c7ecde606a129491 425 SUPERFAMILY SSF51556 115 414 7.99E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS17880 c78b82549dd50341c7ecde606a129491 425 SUPERFAMILY SSF51556 23 51 7.99E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS17880 c78b82549dd50341c7ecde606a129491 425 Pfam PF04909 Amidohydrolase 116 414 6.5E-39 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS32270 4aea4f7872ab846e51281bfee559334a 446 Pfam PF07693 KAP family P-loop domain 22 314 1.4E-37 T 28-03-2018 IPR011646 KAP family P-loop domain SMD44_RS32270 4aea4f7872ab846e51281bfee559334a 446 Gene3D G3DSA:3.40.50.300 19 249 3.4E-13 T 28-03-2018 SMD44_RS32270 4aea4f7872ab846e51281bfee559334a 446 SUPERFAMILY SSF52540 38 90 1.06E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS32270 4aea4f7872ab846e51281bfee559334a 446 SUPERFAMILY SSF52540 162 313 1.06E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 55 72 - T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 SUPERFAMILY SSF48056 3 287 7.68E-60 T 28-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 Pfam PF00264 Common central domain of tyrosinase 30 238 4.2E-41 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 Gene3D G3DSA:1.10.1280.10 2 289 3.0E-66 T 28-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 PRINTS PR00092 Tyrosinase copper-binding domain signature 55 72 9.0E-17 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 PRINTS PR00092 Tyrosinase copper-binding domain signature 198 209 9.0E-17 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 PRINTS PR00092 Tyrosinase copper-binding domain signature 84 89 9.0E-17 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 PRINTS PR00092 Tyrosinase copper-binding domain signature 217 235 9.0E-17 T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS21355 1ad871cffee1d03b0d1db06a41387f07 289 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 218 229 - T 28-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 SMD44_RS20745 eda293c2e74c48b23142b74291ad0ad8 240 Pfam PF12679 ABC-2 family transporter protein 56 169 4.9E-9 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS07535 ec66abeb4259005ad063492a53936d37 241 SUPERFAMILY SSF53098 4 203 7.59E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS07535 ec66abeb4259005ad063492a53936d37 241 Pfam PF00929 Exonuclease 11 179 4.3E-14 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS07535 ec66abeb4259005ad063492a53936d37 241 Gene3D G3DSA:3.30.420.10 8 203 3.4E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS07535 ec66abeb4259005ad063492a53936d37 241 SMART SM00479 8 189 2.6E-20 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS22445 2a17a26476865be8123f3025c7bc4d0e 420 SMART SM00530 18 74 1.8E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS22445 2a17a26476865be8123f3025c7bc4d0e 420 Gene3D G3DSA:1.10.260.40 7 81 6.1E-12 T 28-03-2018 SMD44_RS22445 2a17a26476865be8123f3025c7bc4d0e 420 SUPERFAMILY SSF47413 13 75 5.04E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS22445 2a17a26476865be8123f3025c7bc4d0e 420 Pfam PF13560 Helix-turn-helix domain 15 71 7.8E-11 T 28-03-2018 SMD44_RS24345 5b3da61f4d5ee19f39b25d8b2960e542 444 SUPERFAMILY SSF53383 10 429 3.46E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS24345 5b3da61f4d5ee19f39b25d8b2960e542 444 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 12 433 95.439 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 SMD44_RS24345 5b3da61f4d5ee19f39b25d8b2960e542 444 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 243 279 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS24345 5b3da61f4d5ee19f39b25d8b2960e542 444 Gene3D G3DSA:3.40.640.10 177 318 3.9E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS24345 5b3da61f4d5ee19f39b25d8b2960e542 444 Pfam PF00202 Aminotransferase class-III 42 426 6.1E-81 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS24345 5b3da61f4d5ee19f39b25d8b2960e542 444 Gene3D G3DSA:3.90.1150.10 8 176 2.5E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS24345 5b3da61f4d5ee19f39b25d8b2960e542 444 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 13 429 2.2E-179 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 SMD44_RS24345 5b3da61f4d5ee19f39b25d8b2960e542 444 Gene3D G3DSA:3.90.1150.10 319 436 1.2E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS40160 be16538571e3fdf70ac2c15688249344 117 Pfam PF12840 Helix-turn-helix domain 24 75 1.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40160 be16538571e3fdf70ac2c15688249344 117 SMART SM00418 23 102 4.5E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS40160 be16538571e3fdf70ac2c15688249344 117 SUPERFAMILY SSF46785 9 102 9.68E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40160 be16538571e3fdf70ac2c15688249344 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 25 40 7.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS40160 be16538571e3fdf70ac2c15688249344 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 7.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS40160 be16538571e3fdf70ac2c15688249344 117 Gene3D G3DSA:1.10.10.10 3 114 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36275 972db0e4304647e2ba4dc6b3070995e6 214 Gene3D G3DSA:1.10.260.40 41 92 5.7E-10 T 28-03-2018 SMD44_RS36275 972db0e4304647e2ba4dc6b3070995e6 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS36275 972db0e4304647e2ba4dc6b3070995e6 214 SUPERFAMILY SSF46689 2 72 4.31E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS36275 972db0e4304647e2ba4dc6b3070995e6 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS36275 972db0e4304647e2ba4dc6b3070995e6 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS36275 972db0e4304647e2ba4dc6b3070995e6 214 Gene3D G3DSA:1.10.10.60 5 40 4.2E-16 T 28-03-2018 SMD44_RS03150 8259838a458c81ceb4c52dc51365d0b9 119 SUPERFAMILY SSF46785 6 114 1.44E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03150 8259838a458c81ceb4c52dc51365d0b9 119 Gene3D G3DSA:1.10.10.10 2 118 1.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03150 8259838a458c81ceb4c52dc51365d0b9 119 Pfam PF01638 HxlR-like helix-turn-helix 21 107 6.3E-25 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS42405 20a1bd4bd9766fb4a5037cef98af6a03 206 SUPERFAMILY SSF56091 3 201 3.6E-22 T 28-03-2018 SMD44_RS42405 20a1bd4bd9766fb4a5037cef98af6a03 206 Gene3D G3DSA:3.20.20.120 25 162 2.6E-4 T 28-03-2018 IPR029065 Enolase C-terminal domain-like SMD44_RS42405 20a1bd4bd9766fb4a5037cef98af6a03 206 Pfam PF09414 RNA ligase 37 189 1.0E-15 T 28-03-2018 IPR021122 RNA ligase domain, REL/Rln2 SMD44_RS23045 d3702f8394e1872386e9c3158f36a079 114 Pfam PF00196 Bacterial regulatory proteins, luxR family 23 73 2.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23045 d3702f8394e1872386e9c3158f36a079 114 Gene3D G3DSA:1.10.10.10 3 82 2.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23045 d3702f8394e1872386e9c3158f36a079 114 SMART SM00421 20 77 2.3E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23045 d3702f8394e1872386e9c3158f36a079 114 SUPERFAMILY SSF46894 14 75 5.78E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS23045 d3702f8394e1872386e9c3158f36a079 114 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 37 53 8.7E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23045 d3702f8394e1872386e9c3158f36a079 114 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 53 65 8.7E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS23045 d3702f8394e1872386e9c3158f36a079 114 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 23 37 8.7E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22595 536d1aecf2425976b194c67590fd00ba 267 SUPERFAMILY SSF74650 6 264 1.88E-43 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD44_RS22595 536d1aecf2425976b194c67590fd00ba 267 Pfam PF01263 Aldose 1-epimerase 8 191 3.0E-21 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 SMD44_RS22595 536d1aecf2425976b194c67590fd00ba 267 Gene3D G3DSA:2.70.98.10 2 267 7.9E-46 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMD44_RS00215 009c7628df6ccd115a6931a101508bdb 254 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 82 8.7E-12 T 28-03-2018 IPR027805 Transposase, Helix-turn-helix domain SMD44_RS00215 009c7628df6ccd115a6931a101508bdb 254 Gene3D G3DSA:1.10.10.10 9 243 0.0024 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00215 009c7628df6ccd115a6931a101508bdb 254 Pfam PF13359 DDE superfamily endonuclease 102 249 5.1E-27 T 28-03-2018 IPR027806 Harbinger transposase-derived nuclease domain SMD44_RS43770 52d7d5f47688dcc89b18945814201c72 258 SUPERFAMILY SSF51430 14 254 9.69E-58 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS43770 52d7d5f47688dcc89b18945814201c72 258 Gene3D G3DSA:3.20.20.100 6 256 2.0E-57 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS43770 52d7d5f47688dcc89b18945814201c72 258 Pfam PF00248 Aldo/keto reductase family 19 217 1.3E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS20675 6a9766677c040badcd5d21be79832a19 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 250 5.8E-50 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS20675 6a9766677c040badcd5d21be79832a19 328 Gene3D G3DSA:3.90.25.10 173 327 2.9E-29 T 28-03-2018 SMD44_RS20675 6a9766677c040badcd5d21be79832a19 328 Gene3D G3DSA:3.40.50.720 3 172 5.8E-28 T 28-03-2018 SMD44_RS20675 6a9766677c040badcd5d21be79832a19 328 SUPERFAMILY SSF51735 1 316 9.55E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS20675 6a9766677c040badcd5d21be79832a19 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 321 1.8E-92 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 SMD44_RS34685 f509e4fc9d77cad46af5578592b423a0 459 Gene3D G3DSA:1.20.1250.20 220 428 9.3E-19 T 28-03-2018 SMD44_RS34685 f509e4fc9d77cad46af5578592b423a0 459 Gene3D G3DSA:1.20.1250.20 11 197 9.6E-16 T 28-03-2018 SMD44_RS34685 f509e4fc9d77cad46af5578592b423a0 459 Pfam PF07690 Major Facilitator Superfamily 37 378 8.4E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS34685 f509e4fc9d77cad46af5578592b423a0 459 SUPERFAMILY SSF103473 32 428 2.09E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS40155 4bd5c977914ed2a6d98002a399208329 360 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 345 2.3E-74 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD44_RS40155 4bd5c977914ed2a6d98002a399208329 360 SUPERFAMILY SSF51395 2 357 2.2E-121 T 28-03-2018 SMD44_RS40155 4bd5c977914ed2a6d98002a399208329 360 Gene3D G3DSA:3.20.20.70 1 359 1.6E-129 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS19195 8be63dd1c5857d1a40c974a7ac1a29db 365 Pfam PF01636 Phosphotransferase enzyme family 75 269 3.1E-18 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS19195 8be63dd1c5857d1a40c974a7ac1a29db 365 SUPERFAMILY SSF56112 68 271 6.95E-19 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS19195 8be63dd1c5857d1a40c974a7ac1a29db 365 Gene3D G3DSA:3.90.1200.10 55 354 3.9E-21 T 28-03-2018 SMD44_RS32345 056d9bd7fb05532e197b0d975b46dec6 356 Gene3D G3DSA:3.90.1720.10 193 356 2.1E-13 T 28-03-2018 SMD44_RS32345 056d9bd7fb05532e197b0d975b46dec6 356 Pfam PF00877 NlpC/P60 family 218 327 2.6E-7 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS32345 056d9bd7fb05532e197b0d975b46dec6 356 SUPERFAMILY SSF54001 196 355 4.58E-11 T 28-03-2018 SMD44_RS06970 b1272ed80ac38574a44472b61bf5e79d 465 Pfam PF13529 Peptidase_C39 like family 251 403 5.4E-28 T 28-03-2018 SMD44_RS06970 b1272ed80ac38574a44472b61bf5e79d 465 Gene3D G3DSA:3.90.70.10 272 458 9.3E-19 T 28-03-2018 SMD44_RS05855 093d1b9211e223c1fb5e02cc4638e500 75 SUPERFAMILY SSF47598 4 41 1.15E-5 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMD44_RS05855 093d1b9211e223c1fb5e02cc4638e500 75 Gene3D G3DSA:1.10.1220.10 2 39 3.7E-9 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS05855 093d1b9211e223c1fb5e02cc4638e500 75 Pfam PF05534 HicB family 5 36 7.6E-5 T 28-03-2018 IPR008651 Uncharacterised protein family HicB SMD44_RS02645 c0f8035ed7f231264bcbc1dcf99e70b4 383 SUPERFAMILY SSF55874 282 381 1.12E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS02645 c0f8035ed7f231264bcbc1dcf99e70b4 383 Pfam PF07730 Histidine kinase 179 245 2.9E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS02645 c0f8035ed7f231264bcbc1dcf99e70b4 383 Gene3D G3DSA:3.30.565.10 252 383 2.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS12855 34bbf4f4f8a74990434b79a5ad3bad3e 343 Pfam PF11271 Protein of unknown function (DUF3068) 8 304 1.2E-70 T 28-03-2018 IPR021424 Porin PorA SMD44_RS17310 6ccd8c7e9df5f38156f9c9cb951aa00a 203 PIRSF PIRSF006806 8 199 7.8E-35 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMD44_RS17310 6ccd8c7e9df5f38156f9c9cb951aa00a 203 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 11 196 1.0E-39 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMD44_RS17310 6ccd8c7e9df5f38156f9c9cb951aa00a 203 Gene3D G3DSA:3.40.50.10420 5 203 1.3E-56 T 28-03-2018 SMD44_RS17310 6ccd8c7e9df5f38156f9c9cb951aa00a 203 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 11 196 2.2E-43 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMD44_RS17310 6ccd8c7e9df5f38156f9c9cb951aa00a 203 SUPERFAMILY SSF100950 10 202 5.3E-42 T 28-03-2018 SMD44_RS25200 41fd56221f7766193cea2c2c85932bd2 152 SUPERFAMILY SSF46785 36 146 1.8E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25200 41fd56221f7766193cea2c2c85932bd2 152 Gene3D G3DSA:1.10.10.10 32 151 2.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25200 41fd56221f7766193cea2c2c85932bd2 152 Pfam PF01638 HxlR-like helix-turn-helix 48 133 1.5E-25 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS25180 3ae35a404caf64fff6a77a2fcf454bc3 327 Gene3D G3DSA:3.40.50.880 11 240 4.6E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS25180 3ae35a404caf64fff6a77a2fcf454bc3 327 SUPERFAMILY SSF46689 224 272 8.96E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS25180 3ae35a404caf64fff6a77a2fcf454bc3 327 SUPERFAMILY SSF52317 15 205 9.96E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS25180 3ae35a404caf64fff6a77a2fcf454bc3 327 SMART SM00342 239 322 3.4E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS25180 3ae35a404caf64fff6a77a2fcf454bc3 327 Pfam PF12833 Helix-turn-helix domain 245 324 5.4E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS25180 3ae35a404caf64fff6a77a2fcf454bc3 327 Pfam PF01965 DJ-1/PfpI family 77 184 1.7E-12 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS25180 3ae35a404caf64fff6a77a2fcf454bc3 327 Gene3D G3DSA:1.10.10.60 241 277 3.8E-9 T 28-03-2018 SMD44_RS25180 3ae35a404caf64fff6a77a2fcf454bc3 327 Gene3D G3DSA:1.10.10.60 278 325 1.9E-7 T 28-03-2018 SMD44_RS31585 0b825e89745342e23340f167ffa04423 301 SUPERFAMILY SSF52833 128 219 3.91E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS31585 0b825e89745342e23340f167ffa04423 301 Pfam PF06999 Sucrase/ferredoxin-like 15 214 1.6E-20 T 28-03-2018 IPR009737 Thioredoxin-like ferredoxin SMD44_RS31585 0b825e89745342e23340f167ffa04423 301 Gene3D G3DSA:3.40.30.10 128 221 6.6E-13 T 28-03-2018 SMD44_RS31585 0b825e89745342e23340f167ffa04423 301 PIRSF PIRSF035042 1 301 2.8E-71 T 28-03-2018 IPR010350 Thioredoxin-like ferredoxin, bacteria SMD44_RS28960 4b8783d1c09cbb130a199bb3dc483ca1 875 Gene3D G3DSA:3.40.50.300 110 254 2.2E-9 T 28-03-2018 SMD44_RS28960 4b8783d1c09cbb130a199bb3dc483ca1 875 SUPERFAMILY SSF52540 117 321 1.42E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS03855 a11b603a31c8643f355d03d7341bf054 235 Gene3D G3DSA:3.30.70.100 1 100 5.2E-20 T 28-03-2018 SMD44_RS03855 a11b603a31c8643f355d03d7341bf054 235 Gene3D G3DSA:3.30.70.100 115 215 0.19 T 28-03-2018 SMD44_RS03855 a11b603a31c8643f355d03d7341bf054 235 Pfam PF07978 NIPSNAP 2 98 4.8E-16 T 28-03-2018 IPR012577 NIPSNAP SMD44_RS03855 a11b603a31c8643f355d03d7341bf054 235 SUPERFAMILY SSF54909 1 98 4.54E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS30665 76953d9917f250fae56dd2fd61c08b17 203 SUPERFAMILY SSF46689 3 85 1.69E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS30665 76953d9917f250fae56dd2fd61c08b17 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.5E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30665 76953d9917f250fae56dd2fd61c08b17 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS30665 76953d9917f250fae56dd2fd61c08b17 203 Gene3D G3DSA:1.10.357.10 62 195 1.7E-28 T 28-03-2018 SMD44_RS30665 76953d9917f250fae56dd2fd61c08b17 203 SUPERFAMILY SSF48498 81 195 1.06E-30 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS30665 76953d9917f250fae56dd2fd61c08b17 203 Gene3D G3DSA:1.10.10.60 1 61 3.6E-17 T 28-03-2018 SMD44_RS10170 e29108a3c3e47660e66829f8ed8b9161 139 Gene3D G3DSA:2.102.10.10 36 139 1.3E-21 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS10170 e29108a3c3e47660e66829f8ed8b9161 139 SUPERFAMILY SSF50022 41 135 8.9E-26 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS10170 e29108a3c3e47660e66829f8ed8b9161 139 Pfam PF00355 Rieske [2Fe-2S] domain 44 125 3.5E-16 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS10170 e29108a3c3e47660e66829f8ed8b9161 139 PRINTS PR00162 Rieske 2Fe-2S subunit signature 109 121 2.6E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS10170 e29108a3c3e47660e66829f8ed8b9161 139 PRINTS PR00162 Rieske 2Fe-2S subunit signature 76 87 2.6E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS10170 e29108a3c3e47660e66829f8ed8b9161 139 PRINTS PR00162 Rieske 2Fe-2S subunit signature 96 108 2.6E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 44 486 8.4E-146 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 SUPERFAMILY SSF81442 31 542 6.28E-177 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 35 539 2.2E-214 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 264 318 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 443 464 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 108 132 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 308 323 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 412 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 151 163 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 34 59 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 330 351 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 212 231 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 183 201 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 81 104 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 241 262 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 262 283 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 365 383 1.3E-104 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11405 c611f6c38198ea82f6a4f7aa8f9390d5 578 Gene3D G3DSA:1.20.210.10 30 543 4.0E-197 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS21675 98f01551f8c37dde380e615b4fd2ad8e 147 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 1 146 9.9E-55 T 28-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit SMD44_RS21675 98f01551f8c37dde380e615b4fd2ad8e 147 Gene3D G3DSA:3.30.300.130 1 86 1.8E-18 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SMD44_RS21675 98f01551f8c37dde380e615b4fd2ad8e 147 Pfam PF01883 Iron-sulfur cluster assembly protein 1 63 1.4E-11 T 28-03-2018 IPR002744 MIP18 family-like SMD44_RS21675 98f01551f8c37dde380e615b4fd2ad8e 147 SUPERFAMILY SSF117916 1 84 8.83E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SMD44_RS02830 49d967c9c9a1e6405e03c2288ea61c22 334 SUPERFAMILY SSF161098 125 313 4.19E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02830 49d967c9c9a1e6405e03c2288ea61c22 334 Gene3D G3DSA:1.10.3720.10 43 321 2.9E-45 T 28-03-2018 SMD44_RS02830 49d967c9c9a1e6405e03c2288ea61c22 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 147 330 3.7E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02830 49d967c9c9a1e6405e03c2288ea61c22 334 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 40 75 2.7E-6 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS19205 ed34965d22dd71f96318799e2381604b 238 SUPERFAMILY SSF56784 18 235 1.44E-28 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS19205 ed34965d22dd71f96318799e2381604b 238 Gene3D G3DSA:3.40.50.1000 18 238 1.9E-22 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS19205 ed34965d22dd71f96318799e2381604b 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 111 205 7.9E-13 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS19205 ed34965d22dd71f96318799e2381604b 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 118 200 1.2E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS28155 01cbd161bd537e8df77488a6d5de88bb 174 Pfam PF00293 NUDIX domain 44 156 4.2E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS28155 01cbd161bd537e8df77488a6d5de88bb 174 SUPERFAMILY SSF55811 44 169 3.25E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS28155 01cbd161bd537e8df77488a6d5de88bb 174 Gene3D G3DSA:3.90.79.10 10 174 1.5E-21 T 28-03-2018 SMD44_RS21510 e33cdf52a0512d78854aa40bd23b0c65 384 SUPERFAMILY SSF52518 187 355 5.36E-28 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS21510 e33cdf52a0512d78854aa40bd23b0c65 384 TIGRFAM TIGR03297 Ppyr-DeCO2ase: phosphonopyruvate decarboxylase 15 372 1.0E-107 T 28-03-2018 IPR017684 Phosphonopyruvate decarboxylase GO:0032923|GO:0033980 KEGG: 00440+4.1.1.82|MetaCyc: PWY-5757|MetaCyc: PWY-6322|MetaCyc: PWY-6682|MetaCyc: PWY-6839|MetaCyc: PWY-7510|MetaCyc: PWY-7769 SMD44_RS21510 e33cdf52a0512d78854aa40bd23b0c65 384 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 244 263 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMD44_RS21510 e33cdf52a0512d78854aa40bd23b0c65 384 Gene3D G3DSA:3.40.50.970 4 168 8.7E-22 T 28-03-2018 SMD44_RS21510 e33cdf52a0512d78854aa40bd23b0c65 384 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 231 346 9.6E-17 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD44_RS21510 e33cdf52a0512d78854aa40bd23b0c65 384 Gene3D G3DSA:3.40.50.970 170 371 6.2E-24 T 28-03-2018 SMD44_RS21510 e33cdf52a0512d78854aa40bd23b0c65 384 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 150 1.4E-8 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD44_RS21510 e33cdf52a0512d78854aa40bd23b0c65 384 SUPERFAMILY SSF52518 7 155 4.26E-17 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS38510 026b502667908720f3be6afac0eff93a 325 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 63 319 4.6E-14 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS38510 026b502667908720f3be6afac0eff93a 325 SUPERFAMILY SSF56219 37 324 2.09E-71 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS38510 026b502667908720f3be6afac0eff93a 325 Gene3D G3DSA:3.60.10.10 24 324 1.0E-34 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS38510 026b502667908720f3be6afac0eff93a 325 TIGRFAM TIGR03395 sphingomy: sphingomyelin phosphodiesterase 39 324 6.6E-97 T 28-03-2018 IPR017766 Sphingomyelinase C/phospholipase C GO:0005576|GO:0008081 SMD44_RS21395 5a07a16b977b1c2ef3593cffb08fc6ba 240 ProDom PD190647 REGULATORY RESISTANCE TRANSCRIPTION TRANSCRIPTIONAL ANTIBIOTIC DNA-BINDING ACTIVATOR REGULATION ORF699 NOSIHEPTIDE 1 228 4.0E-33 T 28-03-2018 IPR035214 Protein of unknown function DUF5324 SMD44_RS21395 5a07a16b977b1c2ef3593cffb08fc6ba 240 Pfam PF17258 Family of unknown function (DUF5324) 1 227 8.2E-107 T 28-03-2018 IPR035214 Protein of unknown function DUF5324 SMD44_RS21395 5a07a16b977b1c2ef3593cffb08fc6ba 240 Gene3D G3DSA:1.20.120.20 2 149 5.6E-4 T 28-03-2018 SMD44_RS18995 669d27d34333b93b808b3c60df627d26 134 Gene3D G3DSA:2.30.110.10 2 134 1.1E-22 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS18995 669d27d34333b93b808b3c60df627d26 134 SUPERFAMILY SSF50475 5 132 2.22E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS18995 669d27d34333b93b808b3c60df627d26 134 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 90 1.1E-15 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS18995 669d27d34333b93b808b3c60df627d26 134 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 132 5.3E-39 T 28-03-2018 IPR019920 F420-binding domain, putative SMD44_RS23155 7038b52d2089cde69eb312486e8f3180 324 Gene3D G3DSA:3.40.50.300 3 324 4.9E-55 T 28-03-2018 SMD44_RS23155 7038b52d2089cde69eb312486e8f3180 324 SUPERFAMILY SSF52540 5 225 3.07E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23155 7038b52d2089cde69eb312486e8f3180 324 Pfam PF02374 Anion-transporting ATPase 6 180 3.4E-20 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMD44_RS13805 d629a9ef1ebcd0802a557da07b36426f 255 SMART SM00849 37 232 1.3E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS13805 d629a9ef1ebcd0802a557da07b36426f 255 SUPERFAMILY SSF56281 14 251 1.01E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS13805 d629a9ef1ebcd0802a557da07b36426f 255 Gene3D G3DSA:3.60.15.10 12 252 1.9E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS13805 d629a9ef1ebcd0802a557da07b36426f 255 Pfam PF00753 Metallo-beta-lactamase superfamily 37 232 6.2E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS40760 7c2d9721493f04c0b0c14f3ba62fa46c 153 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS40760 7c2d9721493f04c0b0c14f3ba62fa46c 153 Pfam PF00293 NUDIX domain 4 148 1.6E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS40760 7c2d9721493f04c0b0c14f3ba62fa46c 153 SUPERFAMILY SSF55811 3 149 5.96E-17 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS40760 7c2d9721493f04c0b0c14f3ba62fa46c 153 Gene3D G3DSA:3.90.79.10 1 153 1.7E-22 T 28-03-2018 SMD44_RS08825 d18c5948261388845007ae5ce97cc8eb 463 SUPERFAMILY SSF103473 250 459 4.05E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08825 d18c5948261388845007ae5ce97cc8eb 463 SUPERFAMILY SSF103473 13 204 4.05E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08825 d18c5948261388845007ae5ce97cc8eb 463 Pfam PF07690 Major Facilitator Superfamily 23 322 1.3E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS08825 d18c5948261388845007ae5ce97cc8eb 463 Gene3D G3DSA:1.20.1250.20 253 463 7.3E-24 T 28-03-2018 SMD44_RS08825 d18c5948261388845007ae5ce97cc8eb 463 Gene3D G3DSA:1.20.1250.20 10 200 1.4E-26 T 28-03-2018 SMD44_RS27995 baf06ba3d468db63f58baae3bd6a3273 575 PIRSF PIRSF002741 7 568 9.5E-67 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS27995 baf06ba3d468db63f58baae3bd6a3273 575 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 487 6.3E-76 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS27995 baf06ba3d468db63f58baae3bd6a3273 575 Gene3D G3DSA:3.40.190.10 223 331 7.9E-18 T 28-03-2018 SMD44_RS27995 baf06ba3d468db63f58baae3bd6a3273 575 Gene3D G3DSA:3.90.76.10 58 222 4.1E-30 T 28-03-2018 SMD44_RS27995 baf06ba3d468db63f58baae3bd6a3273 575 Gene3D G3DSA:3.10.105.10 332 545 1.7E-47 T 28-03-2018 SMD44_RS27995 baf06ba3d468db63f58baae3bd6a3273 575 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 105 126 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site SMD44_RS27995 baf06ba3d468db63f58baae3bd6a3273 575 SUPERFAMILY SSF53850 44 563 1.36E-97 T 28-03-2018 SMD44_RS10240 7e0865067961ccbef5d3f3571a01b054 192 Gene3D G3DSA:2.60.60.30 20 185 4.4E-44 T 28-03-2018 SMD44_RS10240 7e0865067961ccbef5d3f3571a01b054 192 Pfam PF02342 TerD domain 2 183 1.8E-43 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS05370 de003762f63c6dbb56fb9e4bd95e99c4 247 SUPERFAMILY SSF53335 15 245 1.84E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS05370 de003762f63c6dbb56fb9e4bd95e99c4 247 Pfam PF13649 Methyltransferase domain 60 159 1.6E-19 T 28-03-2018 SMD44_RS05370 de003762f63c6dbb56fb9e4bd95e99c4 247 Gene3D G3DSA:3.40.50.150 9 245 1.4E-31 T 28-03-2018 SMD44_RS24880 868a5300c1d8dd93604305ce51e6bd82 59 Gene3D G3DSA:1.10.10.620 4 53 1.9E-9 T 28-03-2018 SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 4.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 4.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 4.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 4.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 Pfam PF12802 MarR family 36 93 3.8E-15 T 28-03-2018 SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 SUPERFAMILY SSF46785 14 136 4.51E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 Gene3D G3DSA:1.10.287.100 115 144 4.7E-12 T 28-03-2018 SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 SMART SM00347 29 129 7.0E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS18525 99d50d388871f1fc614e78d66e6eae7e 145 Gene3D G3DSA:1.10.10.10 17 114 1.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32500 963e3e28066ba4a438723a16490706b7 270 SUPERFAMILY SSF53597 51 268 9.28E-37 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS32500 963e3e28066ba4a438723a16490706b7 270 Gene3D G3DSA:3.40.430.10 39 270 1.1E-47 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS32500 963e3e28066ba4a438723a16490706b7 270 Pfam PF01872 RibD C-terminal domain 51 246 1.1E-28 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 Pfam PF02875 Mur ligase family, glutamate ligase domain 338 421 6.6E-22 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 Pfam PF08245 Mur ligase middle domain 116 317 8.1E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 26 490 2.3E-127 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 Gene3D G3DSA:3.40.1190.10 107 342 2.4E-58 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 Gene3D G3DSA:3.40.1390.10 1 106 1.5E-16 T 28-03-2018 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 SUPERFAMILY SSF53244 338 491 1.44E-45 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 491 31.169 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 Gene3D G3DSA:3.90.190.20 343 503 1.0E-42 T 28-03-2018 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 SUPERFAMILY SSF63418 22 106 2.09E-12 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD44_RS16215 47bbed302479ef049168c21820f02972 521 SUPERFAMILY SSF53623 107 337 6.28E-62 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS10100 b787fd90289b169bfb394a5bc9966f81 412 Gene3D G3DSA:1.20.1250.20 209 402 7.2E-19 T 28-03-2018 SMD44_RS10100 b787fd90289b169bfb394a5bc9966f81 412 SUPERFAMILY SSF103473 16 395 9.02E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS10100 b787fd90289b169bfb394a5bc9966f81 412 Pfam PF07690 Major Facilitator Superfamily 18 364 1.8E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS10100 b787fd90289b169bfb394a5bc9966f81 412 Gene3D G3DSA:1.20.1250.20 7 206 4.1E-11 T 28-03-2018 SMD44_RS26315 4a19262d764b83f141ba90b107303957 177 Gene3D G3DSA:3.40.630.30 1 165 1.0E-26 T 28-03-2018 SMD44_RS26315 4a19262d764b83f141ba90b107303957 177 SUPERFAMILY SSF55729 1 155 2.51E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS26315 4a19262d764b83f141ba90b107303957 177 Pfam PF13302 Acetyltransferase (GNAT) domain 8 150 8.9E-30 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 Pfam PF03466 LysR substrate binding domain 96 281 5.3E-23 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 4.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 4.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 4.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 SUPERFAMILY SSF53850 97 281 1.35E-22 T 28-03-2018 SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 SUPERFAMILY SSF46785 14 96 2.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 Gene3D G3DSA:3.40.190.10 182 268 8.9E-17 T 28-03-2018 SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 Gene3D G3DSA:1.10.10.10 9 92 2.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 Gene3D G3DSA:3.40.190.10 93 181 1.6E-9 T 28-03-2018 SMD44_RS15915 c5e4f01ad7edd97ec5ca66c4e50d20fd 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 74 3.4E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS21275 e4b0a498216179162c907c0aef807a0f 387 Pfam PF13480 Acetyltransferase (GNAT) domain 176 320 4.2E-17 T 28-03-2018 SMD44_RS21275 e4b0a498216179162c907c0aef807a0f 387 Gene3D G3DSA:3.40.630.30 1 110 0.0053 T 28-03-2018 SMD44_RS21275 e4b0a498216179162c907c0aef807a0f 387 Gene3D G3DSA:3.40.630.30 124 369 7.1E-14 T 28-03-2018 SMD44_RS21275 e4b0a498216179162c907c0aef807a0f 387 SUPERFAMILY SSF55729 165 332 5.3E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS24405 e585ce1ee5d93a49d10e92fb9968d8c9 483 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 448 1.1E-140 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 SMD44_RS24405 e585ce1ee5d93a49d10e92fb9968d8c9 483 SUPERFAMILY SSF143968 318 483 9.02E-55 T 28-03-2018 SMD44_RS24405 e585ce1ee5d93a49d10e92fb9968d8c9 483 Gene3D G3DSA:3.40.1670.10 318 453 2.2E-40 T 28-03-2018 SMD44_RS24405 e585ce1ee5d93a49d10e92fb9968d8c9 483 SUPERFAMILY SSF50475 3 317 1.96E-115 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS24405 e585ce1ee5d93a49d10e92fb9968d8c9 483 Gene3D G3DSA:1.20.5.570 454 483 4.2E-11 T 28-03-2018 SMD44_RS24405 e585ce1ee5d93a49d10e92fb9968d8c9 483 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 9 440 3.8E-197 T 28-03-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 SMD44_RS24405 e585ce1ee5d93a49d10e92fb9968d8c9 483 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 423 5.3E-159 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 9.6E-23 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 PRINTS PR01755 Bacterial translocase SecF protein signature 237 252 9.6E-23 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 PRINTS PR01755 Bacterial translocase SecF protein signature 154 168 9.6E-23 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 PRINTS PR01755 Bacterial translocase SecF protein signature 202 220 9.6E-23 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 Gene3D G3DSA:1.20.1640.10 63 315 1.2E-24 T 28-03-2018 SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 Pfam PF02355 Protein export membrane protein 112 303 2.7E-66 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 90 291 1.5E-50 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 SUPERFAMILY SSF82866 105 302 1.57E-30 T 28-03-2018 SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 305 23.856 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 294 5.5E-75 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMD44_RS07430 c4685829cd69ff8974ecc3d22531c22d 377 Pfam PF07549 SecD/SecF GG Motif 41 59 4.2E-4 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMD44_RS02345 f6d062839ddad0530f20118393249b8b 332 Gene3D G3DSA:3.40.50.720 3 116 2.6E-30 T 28-03-2018 SMD44_RS02345 f6d062839ddad0530f20118393249b8b 332 SUPERFAMILY SSF52283 23 141 2.84E-28 T 28-03-2018 SMD44_RS02345 f6d062839ddad0530f20118393249b8b 332 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD44_RS02345 f6d062839ddad0530f20118393249b8b 332 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 39 321 1.1E-27 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMD44_RS02345 f6d062839ddad0530f20118393249b8b 332 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMD44_RS02345 f6d062839ddad0530f20118393249b8b 332 SUPERFAMILY SSF51735 110 289 7.24E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02345 f6d062839ddad0530f20118393249b8b 332 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 116 289 1.1E-56 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD44_RS02345 f6d062839ddad0530f20118393249b8b 332 Gene3D G3DSA:3.40.50.720 117 291 4.5E-57 T 28-03-2018 SMD44_RS25790 cf324c000163eab80d2dc517b20f59a9 222 SUPERFAMILY SSF50800 1 219 1.62E-55 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMD44_RS25790 cf324c000163eab80d2dc517b20f59a9 222 Pfam PF03473 MOSC domain 57 170 5.5E-22 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 SMD44_RS25790 cf324c000163eab80d2dc517b20f59a9 222 Gene3D G3DSA:2.40.33.20 1 221 8.4E-47 T 28-03-2018 SMD44_RS18465 e75c2cd56d0f497068ac815520b4a5c7 765 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 611 676 3.0E-7 T 28-03-2018 SMD44_RS18465 e75c2cd56d0f497068ac815520b4a5c7 765 Gene3D G3DSA:2.130.10.130 636 765 1.2E-10 T 28-03-2018 SMD44_RS18465 e75c2cd56d0f497068ac815520b4a5c7 765 Gene3D G3DSA:2.130.10.130 491 635 6.0E-12 T 28-03-2018 SMD44_RS18465 e75c2cd56d0f497068ac815520b4a5c7 765 SUPERFAMILY SSF69318 501 729 1.57E-23 T 28-03-2018 SMD44_RS18465 e75c2cd56d0f497068ac815520b4a5c7 765 Gene3D G3DSA:2.120.10.70 31 236 0.022 T 28-03-2018 SMD44_RS18465 e75c2cd56d0f497068ac815520b4a5c7 765 Gene3D G3DSA:2.120.10.70 242 443 0.064 T 28-03-2018 SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 425 43.262 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 424 5.6E-128 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 SUPERFAMILY SSF51338 367 427 3.17E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 SUPERFAMILY SSF51338 1 50 3.17E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 SUPERFAMILY SSF51556 51 362 2.18E-101 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 Gene3D G3DSA:2.30.40.10 1 64 2.3E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 Pfam PF01979 Amidohydrolase family 47 419 1.4E-18 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMD44_RS07270 242b79c32ff8b4550df3f8a9af6bafb7 428 Gene3D G3DSA:3.20.20.140 65 407 8.5E-94 T 28-03-2018 SMD44_RS26185 09f6c8d4fb4e9e484f83b42c1d4daacc 245 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 243 3.8E-66 T 28-03-2018 SMD44_RS26185 09f6c8d4fb4e9e484f83b42c1d4daacc 245 Gene3D G3DSA:3.20.20.60 1 245 7.1E-59 T 28-03-2018 SMD44_RS26185 09f6c8d4fb4e9e484f83b42c1d4daacc 245 SUPERFAMILY SSF51621 9 244 2.74E-54 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 165 182 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 143 158 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 38 54 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 262 279 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 61 78 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 199 216 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 366 382 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 114 129 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 PRINTS PR01758 Capsule biosynthesis protein CapB signature 297 312 4.9E-33 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 SUPERFAMILY SSF53623 36 201 1.09E-10 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 Gene3D G3DSA:3.40.1190.10 34 246 5.4E-14 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 Pfam PF08245 Mur ligase middle domain 41 201 3.6E-6 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD44_RS32335 49c4dd85d6b3c015a865f7b1dc153771 633 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 7 387 3.1E-116 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 Gene3D G3DSA:3.40.50.620 4 351 9.9E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 1.5E-27 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 PRINTS PR01041 Methionyl-tRNA synthetase signature 263 278 1.5E-27 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 1.5E-27 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 PRINTS PR01041 Methionyl-tRNA synthetase signature 228 239 1.5E-27 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 PRINTS PR01041 Methionyl-tRNA synthetase signature 355 366 1.5E-27 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 1.5E-27 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 SUPERFAMILY SSF47323 356 506 6.35E-23 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 SUPERFAMILY SSF52374 4 354 9.29E-89 T 28-03-2018 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 Pfam PF09334 tRNA synthetases class I (M) 133 367 6.7E-62 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS02870 76462bd7966f54b3ff64157cd1ebad98 510 Gene3D G3DSA:1.10.730.10 352 507 7.7E-25 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS08920 518b7ffa1576b576c770fecf032be4e2 360 Gene3D G3DSA:3.20.20.30 13 266 1.1E-48 T 28-03-2018 SMD44_RS08920 518b7ffa1576b576c770fecf032be4e2 360 PIRSF PIRSF000337 273 357 5.9E-18 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMD44_RS08920 518b7ffa1576b576c770fecf032be4e2 360 PIRSF PIRSF000337 2 265 7.8E-58 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMD44_RS08920 518b7ffa1576b576c770fecf032be4e2 360 Gene3D G3DSA:3.20.20.30 269 359 1.1E-17 T 28-03-2018 SMD44_RS08920 518b7ffa1576b576c770fecf032be4e2 360 Pfam PF00296 Luciferase-like monooxygenase 23 262 1.4E-33 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS08920 518b7ffa1576b576c770fecf032be4e2 360 SUPERFAMILY SSF51679 20 348 4.12E-73 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS04465 ac8eb630c7ed4696d20ef07b88e11184 259 Gene3D G3DSA:2.10.230.10 53 139 0.0054 T 28-03-2018 SMD44_RS07960 7e21a8395265b2d01f7dd3aee23f1c1c 436 SUPERFAMILY SSF56784 71 95 2.75E-13 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS07960 7e21a8395265b2d01f7dd3aee23f1c1c 436 SUPERFAMILY SSF56784 159 311 2.75E-13 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS07960 7e21a8395265b2d01f7dd3aee23f1c1c 436 Gene3D G3DSA:3.40.50.1000 76 358 7.7E-10 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS30600 5487ca8add608b642d3f22cafba1c3f5 569 SUPERFAMILY SSF161098 28 286 1.57E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30600 5487ca8add608b642d3f22cafba1c3f5 569 Gene3D G3DSA:1.10.3720.10 306 568 1.7E-36 T 28-03-2018 SMD44_RS30600 5487ca8add608b642d3f22cafba1c3f5 569 Gene3D G3DSA:1.10.3720.10 31 290 1.2E-40 T 28-03-2018 SMD44_RS30600 5487ca8add608b642d3f22cafba1c3f5 569 SUPERFAMILY SSF161098 306 564 1.57E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30600 5487ca8add608b642d3f22cafba1c3f5 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 379 557 2.5E-7 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30600 5487ca8add608b642d3f22cafba1c3f5 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 272 4.2E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS01665 c3fe20c06745c476032e7c88aca4f988 353 Gene3D G3DSA:3.20.20.100 8 325 6.7E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS01665 c3fe20c06745c476032e7c88aca4f988 353 PRINTS PR00069 Aldo-keto reductase signature 256 280 9.7E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS01665 c3fe20c06745c476032e7c88aca4f988 353 PRINTS PR00069 Aldo-keto reductase signature 113 131 9.7E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS01665 c3fe20c06745c476032e7c88aca4f988 353 Pfam PF00248 Aldo/keto reductase family 20 322 1.1E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS01665 c3fe20c06745c476032e7c88aca4f988 353 SUPERFAMILY SSF51430 8 322 3.67E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS06645 1adffdf1d2b5c77e5bab99a5a096b5df 202 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD44_RS06645 1adffdf1d2b5c77e5bab99a5a096b5df 202 PIRSF PIRSF000847 11 202 1.1E-43 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 SMD44_RS06645 1adffdf1d2b5c77e5bab99a5a096b5df 202 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 85 5.3E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD44_RS34505 aa79d7751b80bf5e7499df82d23a7b3e 370 SUPERFAMILY SSF101478 16 112 1.27E-59 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS34505 aa79d7751b80bf5e7499df82d23a7b3e 370 SUPERFAMILY SSF101478 149 365 1.27E-59 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS34505 aa79d7751b80bf5e7499df82d23a7b3e 370 Pfam PF03747 ADP-ribosylglycohydrolase 22 345 1.2E-65 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS34505 aa79d7751b80bf5e7499df82d23a7b3e 370 Gene3D G3DSA:1.10.4080.10 12 370 1.9E-74 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS28495 ec64f15b75dff7c55f2baab54f5254cf 131 SUPERFAMILY SSF109770 15 131 4.58E-52 T 28-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMD44_RS28495 ec64f15b75dff7c55f2baab54f5254cf 131 Pfam PF09055 Nickel-containing superoxide dismutase 11 129 3.2E-42 T 28-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMD44_RS28495 ec64f15b75dff7c55f2baab54f5254cf 131 Gene3D G3DSA:1.20.120.400 15 129 2.2E-39 T 28-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMD44_RS28495 ec64f15b75dff7c55f2baab54f5254cf 131 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 1 131 8.3E-55 T 28-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 SUPERFAMILY SSF49265 145 342 1.89E-18 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 SMART SM00060 49 122 1.3E-11 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 SMART SM00060 241 328 24.0 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 SMART SM00060 146 222 1.4E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 SUPERFAMILY SSF49265 47 138 9.57E-18 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 Pfam PF00041 Fibronectin type III domain 147 217 7.7E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 Pfam PF00041 Fibronectin type III domain 50 125 1.5E-12 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 Gene3D G3DSA:2.60.40.10 237 344 4.3E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 Gene3D G3DSA:2.60.40.10 141 232 5.6E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS03790 a585b1f5d067d0078403e6d26583439f 344 Gene3D G3DSA:2.60.40.10 44 135 5.8E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS08450 2334d5e7e176c5a416b690970556da98 169 Gene3D G3DSA:3.40.50.300 3 168 2.8E-27 T 28-03-2018 SMD44_RS08450 2334d5e7e176c5a416b690970556da98 169 Pfam PF01202 Shikimate kinase 14 159 6.1E-8 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMD44_RS08450 2334d5e7e176c5a416b690970556da98 169 SUPERFAMILY SSF52540 4 165 2.31E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS08450 2334d5e7e176c5a416b690970556da98 169 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 7 158 5.6E-57 T 28-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 SMD44_RS17630 e27347e487274a25903c81cc6844d2d5 285 SUPERFAMILY SSF47413 10 70 2.53E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS17630 e27347e487274a25903c81cc6844d2d5 285 SMART SM00530 17 72 5.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS17630 e27347e487274a25903c81cc6844d2d5 285 Gene3D G3DSA:1.10.260.40 5 87 1.3E-19 T 28-03-2018 SMD44_RS17630 e27347e487274a25903c81cc6844d2d5 285 Pfam PF13560 Helix-turn-helix domain 13 70 1.2E-16 T 28-03-2018 SMD44_RS39455 95f7bd3eb9e53e02c7692e1574d63b22 243 Pfam PF03734 L,D-transpeptidase catalytic domain 89 234 8.5E-8 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD44_RS39455 95f7bd3eb9e53e02c7692e1574d63b22 243 Gene3D G3DSA:2.40.440.10 69 235 4.6E-8 T 28-03-2018 SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 Gene3D G3DSA:3.40.50.720 45 248 2.7E-66 T 28-03-2018 SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 1.0E-62 T 28-03-2018 SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 192 1.2E-6 T 28-03-2018 SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 SUPERFAMILY SSF51735 8 248 1.22E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 Gene3D G3DSA:3.40.50.10090 5 44 1.5E-7 T 28-03-2018 SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 9.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 9.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 9.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41170 dca7b17e21360af6e1467b3d6bd91c45 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.8E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS39050 674ee21ab6311eeb24eb44d8c0ad76b3 85 Pfam PF01455 HupF/HypC family 2 69 1.3E-25 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD44_RS39050 674ee21ab6311eeb24eb44d8c0ad76b3 85 SUPERFAMILY SSF159127 2 78 1.26E-22 T 28-03-2018 SMD44_RS39050 674ee21ab6311eeb24eb44d8c0ad76b3 85 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.8E-17 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD44_RS39050 674ee21ab6311eeb24eb44d8c0ad76b3 85 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 42 58 1.8E-17 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD44_RS39050 674ee21ab6311eeb24eb44d8c0ad76b3 85 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 60 72 1.8E-17 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD44_RS39050 674ee21ab6311eeb24eb44d8c0ad76b3 85 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 21 37 1.8E-17 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD44_RS39050 674ee21ab6311eeb24eb44d8c0ad76b3 85 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 2 78 4.1E-23 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD44_RS20065 3f0a5a2a2f3d1f74bc47b45846ad826d 82 Gene3D G3DSA:1.10.443.10 5 75 2.7E-7 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS20065 3f0a5a2a2f3d1f74bc47b45846ad826d 82 SUPERFAMILY SSF56349 10 68 2.15E-6 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS11815 cef05c1254d638a847311b7568ae0ed9 165 Gene3D G3DSA:1.25.40.10 46 90 0.067 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS11815 cef05c1254d638a847311b7568ae0ed9 165 SUPERFAMILY SSF48452 37 159 2.53E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS11815 cef05c1254d638a847311b7568ae0ed9 165 Pfam PF12688 Tetratrico peptide repeat 45 161 1.0E-52 T 28-03-2018 SMD44_RS11815 cef05c1254d638a847311b7568ae0ed9 165 Gene3D G3DSA:1.25.40.10 91 163 1.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS22250 30b620777703fa83ee7797ba8bff010b 539 Pfam PF13360 PQQ-like domain 311 437 2.8E-4 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS22250 30b620777703fa83ee7797ba8bff010b 539 Pfam PF13360 PQQ-like domain 147 279 6.9E-15 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS22250 30b620777703fa83ee7797ba8bff010b 539 SUPERFAMILY SSF50998 161 437 2.98E-17 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS22250 30b620777703fa83ee7797ba8bff010b 539 Gene3D G3DSA:2.140.10.10 75 294 3.6E-12 T 28-03-2018 SMD44_RS22250 30b620777703fa83ee7797ba8bff010b 539 Gene3D G3DSA:2.140.10.10 295 507 7.0E-8 T 28-03-2018 SMD44_RS22250 30b620777703fa83ee7797ba8bff010b 539 SMART SM00564 402 439 6.2 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS22250 30b620777703fa83ee7797ba8bff010b 539 SMART SM00564 297 330 6.3 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS22250 30b620777703fa83ee7797ba8bff010b 539 SMART SM00564 154 184 490.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS11260 85f6fdf2da404f4bad7480436cb2f2f2 317 Gene3D G3DSA:3.30.420.40 1 115 7.4E-36 T 28-03-2018 SMD44_RS11260 85f6fdf2da404f4bad7480436cb2f2f2 317 Gene3D G3DSA:3.30.420.40 116 313 1.4E-59 T 28-03-2018 SMD44_RS11260 85f6fdf2da404f4bad7480436cb2f2f2 317 SUPERFAMILY SSF53067 2 312 1.05E-68 T 28-03-2018 SMD44_RS11260 85f6fdf2da404f4bad7480436cb2f2f2 317 ProSitePatterns PS01125 ROK family signature. 130 157 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS11260 85f6fdf2da404f4bad7480436cb2f2f2 317 Pfam PF00480 ROK family 4 312 6.2E-106 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS11260 85f6fdf2da404f4bad7480436cb2f2f2 317 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 312 4.9E-144 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SMD44_RS01740 b47fd753a8e7aba378070f3a69166c6d 196 Gene3D G3DSA:1.10.260.40 44 65 4.1E-10 T 28-03-2018 SMD44_RS01740 b47fd753a8e7aba378070f3a69166c6d 196 SUPERFAMILY SSF48498 84 191 1.01E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS01740 b47fd753a8e7aba378070f3a69166c6d 196 Gene3D G3DSA:1.10.10.60 3 43 1.1E-14 T 28-03-2018 SMD44_RS01740 b47fd753a8e7aba378070f3a69166c6d 196 SUPERFAMILY SSF46689 4 87 1.95E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS01740 b47fd753a8e7aba378070f3a69166c6d 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 1.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS01740 b47fd753a8e7aba378070f3a69166c6d 196 Gene3D G3DSA:1.10.357.10 66 193 2.3E-18 T 28-03-2018 SMD44_RS29620 f4675d99fd1d1f50f506c95522327cba 276 Pfam PF02540 NAD synthase 29 273 7.7E-64 T 28-03-2018 IPR022310 NAD/GMP synthase SMD44_RS29620 f4675d99fd1d1f50f506c95522327cba 276 TIGRFAM TIGR00552 nadE: NAD+ synthetase 24 274 1.2E-63 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 SMD44_RS29620 f4675d99fd1d1f50f506c95522327cba 276 SUPERFAMILY SSF52402 9 274 1.84E-74 T 28-03-2018 SMD44_RS29620 f4675d99fd1d1f50f506c95522327cba 276 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 23 276 32.213 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 SMD44_RS29620 f4675d99fd1d1f50f506c95522327cba 276 Gene3D G3DSA:3.40.50.620 8 276 5.8E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS15000 4bc5b68f270e7a5fc6109f21fbb45bbd 296 Pfam PF14472 Domain of unknown function (DUF4429) 139 225 8.8E-21 T 28-03-2018 IPR027860 Domain of unknown function DUF4429 SMD44_RS15000 4bc5b68f270e7a5fc6109f21fbb45bbd 296 Pfam PF14472 Domain of unknown function (DUF4429) 11 105 2.6E-19 T 28-03-2018 IPR027860 Domain of unknown function DUF4429 SMD44_RS15000 4bc5b68f270e7a5fc6109f21fbb45bbd 296 Pfam PF09851 Short C-terminal domain 267 293 1.6E-7 T 28-03-2018 IPR018649 SHOCT domain SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 2.6E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 SUPERFAMILY SSF52172 1 131 7.12E-32 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 Gene3D G3DSA:3.40.50.2300 1 132 4.4E-36 T 28-03-2018 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 Pfam PF00072 Response regulator receiver domain 4 115 3.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 SMART SM00448 2 114 1.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 Gene3D G3DSA:1.10.10.10 133 215 1.7E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 SUPERFAMILY SSF46894 150 215 3.74E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS28915 3a9e1f047284c9f5d6b3057321e44153 216 SMART SM00421 154 211 1.3E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 PIRSF PIRSF000110 8 507 2.6E-181 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 257 3.7E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 347 373 3.7E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 177 3.7E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 258 274 3.7E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 188 216 3.7E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 Gene3D G3DSA:3.40.50.720 19 209 6.7E-71 T 28-03-2018 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 SUPERFAMILY SSF51735 11 211 3.35E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 23 506 1.7E-202 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 Gene3D G3DSA:3.30.360.10 210 507 1.8E-127 T 28-03-2018 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 21 506 87.563 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 198 204 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 210 505 1.1E-115 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 SUPERFAMILY SSF55347 198 505 6.87E-115 T 28-03-2018 SMD44_RS10075 c8bab8b9fe55f60507ecff818622c1ae 507 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 25 208 8.4E-64 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD44_RS25155 c65d24842bffe32981b3df6a5162f4f4 204 Pfam PF03358 NADPH-dependent FMN reductase 7 137 1.6E-16 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD44_RS25155 c65d24842bffe32981b3df6a5162f4f4 204 SUPERFAMILY SSF52218 7 187 3.47E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS25155 c65d24842bffe32981b3df6a5162f4f4 204 Gene3D G3DSA:3.40.50.360 2 188 7.6E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS22550 9f7d3a372e83d3fa8c0675250f37d7f4 149 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 19 109 2.8E-9 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS22550 9f7d3a372e83d3fa8c0675250f37d7f4 149 Gene3D G3DSA:2.30.110.10 14 146 1.6E-28 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS22550 9f7d3a372e83d3fa8c0675250f37d7f4 149 SUPERFAMILY SSF50475 20 146 1.02E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS34615 c894b5faec4c66acbc9b14e72be1a75e 375 PIRSF PIRSF026166 205 352 2.1E-48 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter SMD44_RS34615 c894b5faec4c66acbc9b14e72be1a75e 375 PIRSF PIRSF026166 2 200 2.5E-67 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter SMD44_RS34615 c894b5faec4c66acbc9b14e72be1a75e 375 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 14 335 3.7E-86 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter SMD44_RS07135 a573685948c132611a9f2403bfc53c83 332 PIRSF PIRSF005739 1 330 5.2E-42 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD44_RS07135 a573685948c132611a9f2403bfc53c83 332 Pfam PF00891 O-methyltransferase 98 312 2.4E-44 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD44_RS07135 a573685948c132611a9f2403bfc53c83 332 Pfam PF16864 Dimerisation domain 3 65 6.9E-7 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain SMD44_RS07135 a573685948c132611a9f2403bfc53c83 332 Gene3D G3DSA:3.40.50.150 87 331 8.9E-43 T 28-03-2018 SMD44_RS07135 a573685948c132611a9f2403bfc53c83 332 Gene3D G3DSA:1.10.10.10 1 86 6.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07135 a573685948c132611a9f2403bfc53c83 332 SUPERFAMILY SSF46785 3 82 6.62E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07135 a573685948c132611a9f2403bfc53c83 332 SUPERFAMILY SSF53335 84 327 3.66E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS42780 9e8e4a3e3c09b8ec1f233143cf83dab5 345 Gene3D G3DSA:3.40.50.20 10 135 1.4E-5 T 28-03-2018 SMD44_RS42780 9e8e4a3e3c09b8ec1f233143cf83dab5 345 SUPERFAMILY SSF56059 122 322 1.44E-12 T 28-03-2018 SMD44_RS42780 9e8e4a3e3c09b8ec1f233143cf83dab5 345 Gene3D G3DSA:3.30.1490.20 136 183 0.0022 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS42780 9e8e4a3e3c09b8ec1f233143cf83dab5 345 Gene3D G3DSA:3.30.470.20 201 309 1.2E-9 T 28-03-2018 SMD44_RS27550 c67d8bf8868746d938fb01bcd887737b 331 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 13 291 3.4E-96 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMD44_RS27550 c67d8bf8868746d938fb01bcd887737b 331 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 11 294 36.631 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMD44_RS27550 c67d8bf8868746d938fb01bcd887737b 331 Gene3D G3DSA:3.40.50.2300 3 284 4.2E-4 T 28-03-2018 SMD44_RS27550 c67d8bf8868746d938fb01bcd887737b 331 Pfam PF02401 LytB protein 13 290 6.0E-88 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMD44_RS35380 e34064fcc588c9433e07eb8f831184f4 665 SUPERFAMILY SSF53474 50 402 2.43E-67 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS35380 e34064fcc588c9433e07eb8f831184f4 665 Gene3D G3DSA:2.60.120.260 396 627 6.7E-39 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS35380 e34064fcc588c9433e07eb8f831184f4 665 SMART SM00939 367 623 1.8E-39 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD44_RS35380 e34064fcc588c9433e07eb8f831184f4 665 SUPERFAMILY SSF49785 422 628 3.19E-37 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS35380 e34064fcc588c9433e07eb8f831184f4 665 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 79 352 7.6E-55 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMD44_RS35380 e34064fcc588c9433e07eb8f831184f4 665 Gene3D G3DSA:3.40.50.1820 45 395 7.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS35380 e34064fcc588c9433e07eb8f831184f4 665 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 379 628 8.2E-45 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 Gene3D G3DSA:1.10.10.10 14 131 1.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 ProSitePatterns PS01117 MarR-type HTH domain signature. 55 89 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 SUPERFAMILY SSF46785 8 127 1.24E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 Pfam PF01047 MarR family 24 80 5.5E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 125 6.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 40 56 6.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 72 6.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 6.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS40435 5201ff035de21e4e399d6f11af3f15d1 131 SMART SM00347 17 115 8.8E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS00460 65275cf9bfa4ac2911ff5a900503b621 138 Gene3D G3DSA:3.30.530.20 3 138 7.4E-21 T 28-03-2018 IPR023393 START-like domain SMD44_RS00460 65275cf9bfa4ac2911ff5a900503b621 138 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 132 2.1E-11 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS00460 65275cf9bfa4ac2911ff5a900503b621 138 SUPERFAMILY SSF55961 1 122 2.47E-20 T 28-03-2018 SMD44_RS20940 941787010f7d0fb093c1b34b835bca88 150 Gene3D G3DSA:3.40.630.30 1 150 2.1E-27 T 28-03-2018 SMD44_RS20940 941787010f7d0fb093c1b34b835bca88 150 Pfam PF00583 Acetyltransferase (GNAT) family 36 139 9.1E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS20940 941787010f7d0fb093c1b34b835bca88 150 SUPERFAMILY SSF55729 2 144 1.66E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS40080 013adc799eba49f5c2aecacd73a98631 279 Gene3D G3DSA:1.10.3720.10 2 267 1.5E-36 T 28-03-2018 SMD44_RS40080 013adc799eba49f5c2aecacd73a98631 279 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 3 52 1.5E-6 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS40080 013adc799eba49f5c2aecacd73a98631 279 SUPERFAMILY SSF161098 71 258 4.06E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS40080 013adc799eba49f5c2aecacd73a98631 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 279 1.2E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS21870 973114e4b000ff60b1083c992fd6a4e9 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 1.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS21870 973114e4b000ff60b1083c992fd6a4e9 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS21870 973114e4b000ff60b1083c992fd6a4e9 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS21870 973114e4b000ff60b1083c992fd6a4e9 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 1.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS21870 973114e4b000ff60b1083c992fd6a4e9 277 Pfam PF00561 alpha/beta hydrolase fold 25 253 3.5E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS21870 973114e4b000ff60b1083c992fd6a4e9 277 Gene3D G3DSA:3.40.50.1820 3 265 1.8E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS21870 973114e4b000ff60b1083c992fd6a4e9 277 SUPERFAMILY SSF53474 16 265 4.4E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS38775 99724811762a6fbdfc522839747109a2 183 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 176 1.8E-54 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SMD44_RS38775 99724811762a6fbdfc522839747109a2 183 Gene3D G3DSA:2.60.120.10 1 183 6.8E-57 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS38775 99724811762a6fbdfc522839747109a2 183 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 182 4.0E-87 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SMD44_RS38775 99724811762a6fbdfc522839747109a2 183 SUPERFAMILY SSF51182 8 178 1.0E-56 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS33780 7ae11f85f377fcb1ac06df5f31a60956 142 SUPERFAMILY SSF55729 5 113 3.74E-6 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS33780 7ae11f85f377fcb1ac06df5f31a60956 142 Gene3D G3DSA:3.40.630.30 1 126 6.4E-8 T 28-03-2018 SMD44_RS12655 5737191b4be3479ae0dd5cdb20367bc1 283 SUPERFAMILY SSF56784 55 240 1.21E-14 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS12655 5737191b4be3479ae0dd5cdb20367bc1 283 SUPERFAMILY SSF56784 17 28 1.21E-14 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS12655 5737191b4be3479ae0dd5cdb20367bc1 283 Gene3D G3DSA:3.40.50.1000 17 260 1.8E-9 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 SUPERFAMILY SSF52540 335 571 1.41E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 SUPERFAMILY SSF90123 671 987 3.14E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 Pfam PF00664 ABC transporter transmembrane region 683 953 2.4E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 Pfam PF00664 ABC transporter transmembrane region 27 294 3.0E-36 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 Pfam PF00005 ABC transporter 355 504 1.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 Pfam PF00005 ABC transporter 1018 1167 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 SUPERFAMILY SSF52540 990 1252 8.7E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 SMART SM00382 1027 1229 5.3E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 SMART SM00382 364 550 7.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 Gene3D G3DSA:1.20.1560.10 2 327 3.4E-64 T 28-03-2018 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 Gene3D G3DSA:1.20.1560.10 666 989 3.7E-61 T 28-03-2018 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 Gene3D G3DSA:3.40.50.300 996 1250 1.3E-68 T 28-03-2018 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 SUPERFAMILY SSF90123 8 326 2.09E-72 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS14885 c7701b520a1d3c1e83ac4f62795f2983 1260 Gene3D G3DSA:3.40.50.300 329 577 3.2E-71 T 28-03-2018 SMD44_RS05170 29d481b76d51533f4b9d5db8b705c9b1 452 SUPERFAMILY SSF55729 251 400 8.8E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS05170 29d481b76d51533f4b9d5db8b705c9b1 452 Gene3D G3DSA:3.90.190.10 19 183 3.5E-27 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMD44_RS05170 29d481b76d51533f4b9d5db8b705c9b1 452 Pfam PF13673 Acetyltransferase (GNAT) domain 289 400 1.8E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS05170 29d481b76d51533f4b9d5db8b705c9b1 452 SUPERFAMILY SSF52799 5 241 1.39E-48 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMD44_RS05170 29d481b76d51533f4b9d5db8b705c9b1 452 Pfam PF13350 Tyrosine phosphatase family 5 242 4.4E-61 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type SMD44_RS05170 29d481b76d51533f4b9d5db8b705c9b1 452 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 137 147 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 SMD44_RS05170 29d481b76d51533f4b9d5db8b705c9b1 452 Gene3D G3DSA:3.40.630.30 233 417 3.8E-24 T 28-03-2018 SMD44_RS15490 fcd96ca61a40dacb5f6b75d8de5224f7 132 SUPERFAMILY SSF52980 1 114 3.22E-34 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS15490 fcd96ca61a40dacb5f6b75d8de5224f7 132 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 107 2.0E-37 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 SMD44_RS15490 fcd96ca61a40dacb5f6b75d8de5224f7 132 Gene3D G3DSA:3.40.960.10 8 130 7.0E-27 T 28-03-2018 SMD44_RS15490 fcd96ca61a40dacb5f6b75d8de5224f7 132 Pfam PF03852 DNA mismatch endonuclease Vsr 1 60 2.4E-17 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 SMD44_RS13745 85ebec7e44e2ab0b4eae2b32e48f4d30 373 Pfam PF02562 PhoH-like protein 148 351 4.3E-95 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 SMD44_RS13745 85ebec7e44e2ab0b4eae2b32e48f4d30 373 Gene3D G3DSA:3.40.50.300 145 351 1.3E-30 T 28-03-2018 SMD44_RS13745 85ebec7e44e2ab0b4eae2b32e48f4d30 373 SUPERFAMILY SSF52540 141 326 2.84E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 SUPERFAMILY SSF55973 250 401 2.55E-67 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 SUPERFAMILY SSF55973 120 248 1.96E-44 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 Gene3D G3DSA:3.30.300.10 136 248 2.3E-39 T 28-03-2018 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 Pfam PF02772 S-adenosylmethionine synthetase, central domain 124 248 2.7E-43 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 56.531 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 399 7.1E-168 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 PIRSF PIRSF000497 1 401 1.6E-162 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 2.7E-67 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 Gene3D G3DSA:3.30.300.10 11 135 9.9E-43 T 28-03-2018 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 9.5E-40 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 SUPERFAMILY SSF55973 3 109 5.49E-44 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD44_RS07220 4a22bda2a67c74c0843ac304bd2c33e8 402 Gene3D G3DSA:3.30.300.10 265 402 6.4E-49 T 28-03-2018 SMD44_RS20945 95f2b55a432531b6ef970bdce958ab6d 457 SUPERFAMILY SSF56601 14 323 1.56E-70 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS20945 95f2b55a432531b6ef970bdce958ab6d 457 Gene3D G3DSA:3.40.710.10 8 338 1.3E-70 T 28-03-2018 SMD44_RS20945 95f2b55a432531b6ef970bdce958ab6d 457 Pfam PF00144 Beta-lactamase 18 329 2.2E-57 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS17790 d8fd44472e85222e44639b9ea624816f 302 Gene3D G3DSA:3.20.20.70 180 266 2.3E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS17790 d8fd44472e85222e44639b9ea624816f 302 Gene3D G3DSA:3.20.20.70 2 179 4.4E-24 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS17790 d8fd44472e85222e44639b9ea624816f 302 SUPERFAMILY SSF102114 10 247 4.71E-37 T 28-03-2018 SMD44_RS17790 d8fd44472e85222e44639b9ea624816f 302 Pfam PF13186 Iron-sulfur cluster-binding domain 203 272 1.1E-6 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain SMD44_RS17790 d8fd44472e85222e44639b9ea624816f 302 Pfam PF04055 Radical SAM superfamily 14 149 3.4E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS26465 388e7edf57ac255e14404d0634238b27 315 PIRSF PIRSF035875 12 302 2.9E-28 T 28-03-2018 IPR017039 Virulence factor BrkB SMD44_RS26465 388e7edf57ac255e14404d0634238b27 315 Pfam PF03631 Virulence factor BrkB 33 280 5.0E-46 T 28-03-2018 IPR017039 Virulence factor BrkB SMD44_RS10190 48099c7a8796935869469f5c8362db0e 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 234 2.8E-40 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS10190 48099c7a8796935869469f5c8362db0e 263 Gene3D G3DSA:3.90.226.10 1 259 5.2E-61 T 28-03-2018 SMD44_RS10190 48099c7a8796935869469f5c8362db0e 263 SUPERFAMILY SSF52096 8 251 3.2E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS10190 48099c7a8796935869469f5c8362db0e 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD44_RS27770 0d377498dbdd14cbfacd7e30d1f1d98f 264 Pfam PF12698 ABC-2 family transporter protein 68 249 9.3E-12 T 28-03-2018 SMD44_RS27770 0d377498dbdd14cbfacd7e30d1f1d98f 264 PIRSF PIRSF006648 1 261 1.5E-20 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS41800 dd1675f765c053223f618593144ce047 285 Pfam PF01380 SIS domain 133 258 4.3E-12 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMD44_RS41800 dd1675f765c053223f618593144ce047 285 SUPERFAMILY SSF53697 109 265 1.13E-14 T 28-03-2018 SMD44_RS41800 dd1675f765c053223f618593144ce047 285 Gene3D G3DSA:3.40.50.10490 86 283 1.1E-19 T 28-03-2018 SMD44_RS41800 dd1675f765c053223f618593144ce047 285 SUPERFAMILY SSF46689 14 86 8.42E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS41800 dd1675f765c053223f618593144ce047 285 Gene3D G3DSA:1.10.10.10 11 85 4.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13895 940367fbf57e645180c6694d1bae6912 530 SUPERFAMILY SSF54862 440 499 8.37E-7 T 28-03-2018 SMD44_RS13895 940367fbf57e645180c6694d1bae6912 530 SUPERFAMILY SSF140490 322 419 1.96E-16 T 28-03-2018 SMD44_RS13895 940367fbf57e645180c6694d1bae6912 530 SMART SM00928 325 369 8.1E-4 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS13895 940367fbf57e645180c6694d1bae6912 530 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 55 217 3.4E-31 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS13895 940367fbf57e645180c6694d1bae6912 530 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 328 409 7.4E-15 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS13895 940367fbf57e645180c6694d1bae6912 530 Pfam PF13459 4Fe-4S single cluster domain 442 498 4.3E-12 T 28-03-2018 SMD44_RS13895 940367fbf57e645180c6694d1bae6912 530 SUPERFAMILY SSF142984 242 316 1.83E-7 T 28-03-2018 SMD44_RS13895 940367fbf57e645180c6694d1bae6912 530 SUPERFAMILY SSF142019 29 239 1.02E-33 T 28-03-2018 SMD44_RS18940 9e28b3ed5b2aa2547ab62134f0db0052 300 Gene3D G3DSA:3.90.1200.10 111 293 5.1E-10 T 28-03-2018 SMD44_RS18940 9e28b3ed5b2aa2547ab62134f0db0052 300 SUPERFAMILY SSF56112 37 283 1.09E-28 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS18940 9e28b3ed5b2aa2547ab62134f0db0052 300 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 39 283 1.5E-59 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 SMD44_RS05235 8204bf5ae21105c442dc6af4690bdcc6 264 SUPERFAMILY SSF53474 16 256 1.51E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05235 8204bf5ae21105c442dc6af4690bdcc6 264 Pfam PF00975 Thioesterase domain 36 258 1.7E-50 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS05235 8204bf5ae21105c442dc6af4690bdcc6 264 SMART SM00824 Thioesterase 38 258 0.0023 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD44_RS05235 8204bf5ae21105c442dc6af4690bdcc6 264 Gene3D G3DSA:3.40.50.1820 16 259 6.5E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS03315 23a6cca444f463b7e9e49cdecb5f15ff 295 Pfam PF07676 WD40-like Beta Propeller Repeat 122 137 0.13 T 28-03-2018 IPR011659 WD40-like Beta Propeller SMD44_RS03315 23a6cca444f463b7e9e49cdecb5f15ff 295 Pfam PF07676 WD40-like Beta Propeller Repeat 19 48 0.13 T 28-03-2018 IPR011659 WD40-like Beta Propeller SMD44_RS03315 23a6cca444f463b7e9e49cdecb5f15ff 295 Gene3D G3DSA:2.130.10.10 2 117 8.0E-14 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS03315 23a6cca444f463b7e9e49cdecb5f15ff 295 Gene3D G3DSA:2.130.10.10 118 223 2.1E-6 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS03315 23a6cca444f463b7e9e49cdecb5f15ff 295 SUPERFAMILY SSF69304 20 196 1.29E-18 T 28-03-2018 SMD44_RS11005 fae1a5df738f523d2e6a69dd29acba9a 239 PIRSF PIRSF004848 1 239 4.9E-65 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SMD44_RS11005 fae1a5df738f523d2e6a69dd29acba9a 239 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SMD44_RS11005 fae1a5df738f523d2e6a69dd29acba9a 239 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 9 235 1.7E-42 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SMD44_RS11005 fae1a5df738f523d2e6a69dd29acba9a 239 SUPERFAMILY SSF51419 4 233 7.41E-60 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS11005 fae1a5df738f523d2e6a69dd29acba9a 239 Pfam PF01168 Alanine racemase, N-terminal domain 12 235 1.8E-20 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS11005 fae1a5df738f523d2e6a69dd29acba9a 239 Gene3D G3DSA:3.20.20.10 1 237 3.7E-60 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS00655 f7991e0e920cd8d95ee832d6bde51c5b 182 Pfam PF11706 CGNR zinc finger 135 177 1.7E-17 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS00655 f7991e0e920cd8d95ee832d6bde51c5b 182 SUPERFAMILY SSF160904 3 176 7.19E-42 T 28-03-2018 SMD44_RS00655 f7991e0e920cd8d95ee832d6bde51c5b 182 Pfam PF07336 Putative stress-induced transcription regulator 9 128 4.3E-17 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS00655 f7991e0e920cd8d95ee832d6bde51c5b 182 Gene3D G3DSA:1.10.3300.10 1 179 3.2E-45 T 28-03-2018 IPR023286 ABATE domain SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 ProSitePatterns PS00605 ATP synthase c subunit signature. 45 66 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 SUPERFAMILY SSF81333 19 78 3.66E-16 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 25 75 6.3E-15 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 Hamap MF_01396 ATP synthase subunit c [atpH]. 15 80 14.599 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 PRINTS PR00124 ATP synthase C subunit signature 38 53 1.4E-16 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 PRINTS PR00124 ATP synthase C subunit signature 55 80 1.4E-16 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 PRINTS PR00124 ATP synthase C subunit signature 17 36 1.4E-16 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 Pfam PF00137 ATP synthase subunit C 22 76 4.5E-11 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SMD44_RS28870 52d28ab1fdd91e24439e2b2c0790cdf0 81 Gene3D G3DSA:1.20.20.10 13 79 1.2E-17 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SMD44_RS14020 43dcda9375eae8e369804df35976d270 266 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 220 1.3E-52 T 28-03-2018 IPR018768 Domain of unknown function DUF2344 SMD44_RS14020 43dcda9375eae8e369804df35976d270 266 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 196 1.1E-47 T 28-03-2018 IPR018768 Domain of unknown function DUF2344 SMD44_RS08125 7caccd880502410ef16ea2fbd4b07045 453 PIRSF PIRSF018077 1 453 4.6E-182 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMD44_RS08125 7caccd880502410ef16ea2fbd4b07045 453 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 1.0E-231 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 SMD44_RS08125 7caccd880502410ef16ea2fbd4b07045 453 Pfam PF03136 Pup-ligase protein 4 423 6.6E-157 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMD44_RS08125 7caccd880502410ef16ea2fbd4b07045 453 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 50.144 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 SMD44_RS32430 b71d608bf0e6e5f84038de7447514010 462 SUPERFAMILY SSF51658 23 220 2.49E-10 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS32430 b71d608bf0e6e5f84038de7447514010 462 Pfam PF05114 Protein of unknown function (DUF692) 6 270 3.0E-80 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 SMD44_RS32430 b71d608bf0e6e5f84038de7447514010 462 Gene3D G3DSA:3.20.20.150 1 282 3.7E-74 T 28-03-2018 SMD44_RS19255 6475438a85d2e812d76370cf4c295dd5 190 Gene3D G3DSA:2.40.128.20 1 167 2.0E-58 T 28-03-2018 IPR012674 Calycin SMD44_RS19255 6475438a85d2e812d76370cf4c295dd5 190 SUPERFAMILY SSF50814 7 165 1.49E-40 T 28-03-2018 IPR012674 Calycin SMD44_RS19255 6475438a85d2e812d76370cf4c295dd5 190 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 4 166 31.894 T 28-03-2018 IPR022939 Uncharacterised protein family UPF0678 SMD44_RS19255 6475438a85d2e812d76370cf4c295dd5 190 Pfam PF08768 Domain of unknown function (DUF1794) 12 164 4.8E-49 T 28-03-2018 IPR014878 Domain of unknown function DUF1794 SMD44_RS14810 226fd1b66671d5b239dac5155f1612fd 383 Gene3D G3DSA:3.40.50.720 1 153 4.1E-29 T 28-03-2018 SMD44_RS14810 226fd1b66671d5b239dac5155f1612fd 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 137 5.6E-10 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS14810 226fd1b66671d5b239dac5155f1612fd 383 Gene3D G3DSA:3.30.360.10 154 382 9.7E-39 T 28-03-2018 SMD44_RS14810 226fd1b66671d5b239dac5155f1612fd 383 SUPERFAMILY SSF51735 4 173 1.38E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS14810 226fd1b66671d5b239dac5155f1612fd 383 SUPERFAMILY SSF55347 146 343 2.94E-30 T 28-03-2018 SMD44_RS43360 b965e6fcfab51292195e7b4a04328fdd 443 Gene3D G3DSA:3.90.1530.10 13 147 1.0E-13 T 28-03-2018 SMD44_RS43360 b965e6fcfab51292195e7b4a04328fdd 443 SMART SM00470 38 141 6.6E-6 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS43360 b965e6fcfab51292195e7b4a04328fdd 443 Pfam PF02195 ParB-like nuclease domain 55 140 5.3E-9 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS43360 b965e6fcfab51292195e7b4a04328fdd 443 SUPERFAMILY SSF110849 54 143 1.22E-9 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS10290 6889cc980c73b0a253b2909a0e7a93af 384 SUPERFAMILY SSF144083 320 381 2.09E-19 T 28-03-2018 SMD44_RS10290 6889cc980c73b0a253b2909a0e7a93af 384 Gene3D G3DSA:3.30.460.20 25 195 3.4E-36 T 28-03-2018 SMD44_RS10290 6889cc980c73b0a253b2909a0e7a93af 384 Pfam PF01544 CorA-like Mg2+ transporter protein 84 380 3.2E-59 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD44_RS10290 6889cc980c73b0a253b2909a0e7a93af 384 Gene3D G3DSA:1.20.58.340 198 316 1.9E-32 T 28-03-2018 SMD44_RS10290 6889cc980c73b0a253b2909a0e7a93af 384 Gene3D G3DSA:1.20.58.340 317 384 8.2E-19 T 28-03-2018 SMD44_RS10290 6889cc980c73b0a253b2909a0e7a93af 384 SUPERFAMILY SSF143865 70 316 7.59E-62 T 28-03-2018 SMD44_RS20700 bb145386299f3a1964d3e9df5cb81b9c 247 Pfam PF07987 Domain of unkown function (DUF1775) 29 177 5.6E-49 T 28-03-2018 IPR012533 YcnI-like SMD44_RS27885 95e23b07c6bd8c986cea54ad543cfaac 377 Pfam PF01883 Iron-sulfur cluster assembly protein 4 76 3.9E-18 T 28-03-2018 IPR002744 MIP18 family-like SMD44_RS27885 95e23b07c6bd8c986cea54ad543cfaac 377 SUPERFAMILY SSF52540 111 360 1.13E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27885 95e23b07c6bd8c986cea54ad543cfaac 377 Hamap MF_02040 Iron-sulfur cluster carrier protein. 102 358 35.148 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein SMD44_RS27885 95e23b07c6bd8c986cea54ad543cfaac 377 SUPERFAMILY SSF117916 1 88 5.89E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SMD44_RS27885 95e23b07c6bd8c986cea54ad543cfaac 377 Gene3D G3DSA:3.40.50.300 87 365 3.4E-59 T 28-03-2018 SMD44_RS27885 95e23b07c6bd8c986cea54ad543cfaac 377 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 111 357 1.4E-92 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 SMD44_RS27885 95e23b07c6bd8c986cea54ad543cfaac 377 Gene3D G3DSA:3.30.300.130 1 86 1.3E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain SMD44_RS27885 95e23b07c6bd8c986cea54ad543cfaac 377 ProSitePatterns PS01215 Mrp family signature. 215 231 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 SMD44_RS33385 fe8f72f35f3a81b30df3e941095ee7ec 213 Pfam PF14273 Domain of unknown function (DUF4360) 34 212 2.7E-68 T 28-03-2018 IPR025649 Protein of unknown function DUF4360 SMD44_RS34880 a80cdbb102b6b0eb10e6a2502e9890c6 456 Gene3D G3DSA:3.40.1190.20 59 406 0.0011 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS34880 a80cdbb102b6b0eb10e6a2502e9890c6 456 Pfam PF13148 Protein of unknown function (DUF3987) 118 310 3.0E-11 T 28-03-2018 IPR025048 Protein of unknown function DUF3987) SMD44_RS00805 4b5656204e0a1de0c062ca7113836b5b 200 SUPERFAMILY SSF47413 10 73 1.46E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS00805 4b5656204e0a1de0c062ca7113836b5b 200 Pfam PF07883 Cupin domain 117 178 3.3E-13 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS00805 4b5656204e0a1de0c062ca7113836b5b 200 Pfam PF13560 Helix-turn-helix domain 12 70 4.0E-15 T 28-03-2018 SMD44_RS00805 4b5656204e0a1de0c062ca7113836b5b 200 SUPERFAMILY SSF51182 68 178 1.01E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS00805 4b5656204e0a1de0c062ca7113836b5b 200 SMART SM00530 15 70 4.0E-18 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS00805 4b5656204e0a1de0c062ca7113836b5b 200 Gene3D G3DSA:1.10.260.40 4 69 1.7E-19 T 28-03-2018 SMD44_RS00805 4b5656204e0a1de0c062ca7113836b5b 200 Gene3D G3DSA:2.60.120.10 70 200 1.6E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS09580 4f784594cde5c910258caae84c25bcc1 424 Pfam PF01384 Phosphate transporter family 22 320 3.2E-78 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMD44_RS14835 a3671466ae03dd2472e8de0a7f0358f4 341 Gene3D G3DSA:2.120.10.30 16 190 1.3E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMD44_RS14835 a3671466ae03dd2472e8de0a7f0358f4 341 SUPERFAMILY SSF63829 59 297 1.86E-21 T 28-03-2018 SMD44_RS14835 a3671466ae03dd2472e8de0a7f0358f4 341 Gene3D G3DSA:2.130.10.120 191 331 1.0E-5 T 28-03-2018 SMD44_RS34845 c870ca2617d2002772a16cf597b51103 52 Gene3D G3DSA:1.10.10.10 1 52 1.9E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34845 c870ca2617d2002772a16cf597b51103 52 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 1 47 7.0E-9 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD44_RS34845 c870ca2617d2002772a16cf597b51103 52 Pfam PF12728 Helix-turn-helix domain 1 49 2.0E-11 T 28-03-2018 SMD44_RS20800 48e91bb8021f20989b280f4ad8960c05 371 Pfam PF01551 Peptidase family M23 263 350 9.8E-26 T 28-03-2018 IPR016047 Peptidase M23 SMD44_RS20800 48e91bb8021f20989b280f4ad8960c05 371 Gene3D G3DSA:2.70.70.10 149 367 1.6E-39 T 28-03-2018 SMD44_RS20800 48e91bb8021f20989b280f4ad8960c05 371 SUPERFAMILY SSF51261 186 364 5.02E-39 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS02570 e7fe253c2d56d30ca3efa2f7f74953d3 214 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 136 1.0E-17 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS02570 e7fe253c2d56d30ca3efa2f7f74953d3 214 SUPERFAMILY SSF109854 9 132 9.46E-19 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS02570 e7fe253c2d56d30ca3efa2f7f74953d3 214 Gene3D G3DSA:1.20.120.450 2 194 2.1E-21 T 28-03-2018 SMD44_RS02570 e7fe253c2d56d30ca3efa2f7f74953d3 214 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 195 4.6E-33 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS40660 8d4aa2146ddf38546fd9be42b8d52a1e 200 SUPERFAMILY SSF48452 42 182 2.78E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40660 8d4aa2146ddf38546fd9be42b8d52a1e 200 Pfam PF13424 Tetratricopeptide repeat 91 158 9.6E-13 T 28-03-2018 SMD44_RS40660 8d4aa2146ddf38546fd9be42b8d52a1e 200 Pfam PF13374 Tetratricopeptide repeat 46 87 6.8E-8 T 28-03-2018 SMD44_RS40660 8d4aa2146ddf38546fd9be42b8d52a1e 200 Gene3D G3DSA:1.10.10.10 72 109 5.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40660 8d4aa2146ddf38546fd9be42b8d52a1e 200 Gene3D G3DSA:1.10.10.10 110 194 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS40660 8d4aa2146ddf38546fd9be42b8d52a1e 200 Gene3D G3DSA:1.10.10.10 37 71 4.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09715 c62d3a53c30229600bb1fb2f09bc571f 356 Gene3D G3DSA:3.20.20.70 1 356 6.8E-118 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS09715 c62d3a53c30229600bb1fb2f09bc571f 356 SUPERFAMILY SSF51395 2 353 3.36E-113 T 28-03-2018 SMD44_RS09715 c62d3a53c30229600bb1fb2f09bc571f 356 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 330 2.2E-74 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD44_RS32405 18b9692f088f3c8d82e56cd3f1212960 239 SUPERFAMILY SSF54909 19 238 1.53E-75 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS32405 18b9692f088f3c8d82e56cd3f1212960 239 Gene3D G3DSA:3.30.70.1030 18 132 1.8E-40 T 28-03-2018 SMD44_RS32405 18b9692f088f3c8d82e56cd3f1212960 239 Pfam PF06778 Chlorite dismutase 44 228 2.7E-74 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase SMD44_RS32405 18b9692f088f3c8d82e56cd3f1212960 239 Gene3D G3DSA:3.30.70.1100 136 236 2.9E-28 T 28-03-2018 SMD44_RS09635 1b028915156872abe349b63c2b8432bf 246 SUPERFAMILY SSF53790 7 236 2.36E-41 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09635 1b028915156872abe349b63c2b8432bf 246 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 216 7.3E-46 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09635 1b028915156872abe349b63c2b8432bf 246 Gene3D G3DSA:3.40.1010.10 6 153 2.9E-28 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD44_RS09635 1b028915156872abe349b63c2b8432bf 246 PIRSF PIRSF036427 4 243 3.0E-72 T 28-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 SMD44_RS09635 1b028915156872abe349b63c2b8432bf 246 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 7 235 2.7E-73 T 28-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 SMD44_RS16895 e416f446d9769bd13cb1dda7ddead6a2 527 Pfam PF00474 Sodium:solute symporter family 30 444 6.8E-50 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS21735 765036fadc56ccd73906234f8fed0293 334 SUPERFAMILY SSF52922 196 327 1.26E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS21735 765036fadc56ccd73906234f8fed0293 334 SUPERFAMILY SSF52518 8 193 2.69E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold SMD44_RS21735 765036fadc56ccd73906234f8fed0293 334 Pfam PF02779 Transketolase, pyrimidine binding domain 9 182 2.8E-46 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS21735 765036fadc56ccd73906234f8fed0293 334 Gene3D G3DSA:3.40.50.970 5 200 2.9E-63 T 28-03-2018 SMD44_RS21735 765036fadc56ccd73906234f8fed0293 334 SMART SM00861 9 184 1.4E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMD44_RS21735 765036fadc56ccd73906234f8fed0293 334 Pfam PF02780 Transketolase, C-terminal domain 200 321 1.3E-36 T 28-03-2018 IPR033248 Transketolase, C-terminal domain SMD44_RS21735 765036fadc56ccd73906234f8fed0293 334 Gene3D G3DSA:3.40.50.920 201 329 2.8E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD44_RS15615 10dd509f8445ff0505387ee90e5aa1cc 132 Gene3D G3DSA:1.20.120.570 28 129 4.5E-6 T 28-03-2018 SMD44_RS37105 a55eab32e08e5f8a558bceef276cdf32 352 Pfam PF12833 Helix-turn-helix domain 228 304 3.0E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS37105 a55eab32e08e5f8a558bceef276cdf32 352 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 300 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS37105 a55eab32e08e5f8a558bceef276cdf32 352 SUPERFAMILY SSF46689 209 256 5.02E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS37105 a55eab32e08e5f8a558bceef276cdf32 352 Gene3D G3DSA:2.60.120.10 5 149 1.0E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS37105 a55eab32e08e5f8a558bceef276cdf32 352 SMART SM00342 222 304 2.7E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS37105 a55eab32e08e5f8a558bceef276cdf32 352 SUPERFAMILY SSF51182 81 183 4.83E-12 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS37105 a55eab32e08e5f8a558bceef276cdf32 352 Gene3D G3DSA:1.10.10.60 263 309 0.0016 T 28-03-2018 SMD44_RS37105 a55eab32e08e5f8a558bceef276cdf32 352 Gene3D G3DSA:1.10.10.60 202 262 7.0E-11 T 28-03-2018 SMD44_RS34360 321cd41722b7db68711fb144b5cb0dcb 190 Gene3D G3DSA:1.20.120.20 51 186 1.7E-5 T 28-03-2018 SMD44_RS04805 a9299e6b832bd786089d03d5ef9dfdfb 124 Gene3D G3DSA:2.60.20.10 23 124 2.1E-7 T 28-03-2018 SMD44_RS12890 2489a8ed31a12fee8f173c3f18376b5c 85 Gene3D G3DSA:2.20.25.10 10 84 4.2E-18 T 28-03-2018 SMD44_RS12890 2489a8ed31a12fee8f173c3f18376b5c 85 Pfam PF03966 Trm112p-like protein 5 59 5.3E-9 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 SMD44_RS12890 2489a8ed31a12fee8f173c3f18376b5c 85 SUPERFAMILY SSF158997 4 76 2.62E-13 T 28-03-2018 SMD44_RS03930 d4b220edc9556118b722ed354fe1eb36 156 Pfam PF00293 NUDIX domain 22 133 3.8E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS03930 d4b220edc9556118b722ed354fe1eb36 156 SUPERFAMILY SSF55811 9 137 3.52E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS03930 d4b220edc9556118b722ed354fe1eb36 156 Gene3D G3DSA:3.90.79.10 5 153 3.0E-30 T 28-03-2018 SMD44_RS25035 d7152c48615604b86e83445bcff741e8 444 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 42 444 7.6E-175 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25035 d7152c48615604b86e83445bcff741e8 444 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 79 90 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25035 d7152c48615604b86e83445bcff741e8 444 SUPERFAMILY SSF56762 52 444 9.81E-124 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25035 d7152c48615604b86e83445bcff741e8 444 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 159 444 1.3E-115 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25035 d7152c48615604b86e83445bcff741e8 444 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 38 444 47.091 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25035 d7152c48615604b86e83445bcff741e8 444 Gene3D G3DSA:1.10.645.10 234 440 1.8E-46 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25035 d7152c48615604b86e83445bcff741e8 444 Gene3D G3DSA:1.10.645.10 38 233 1.2E-48 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS05220 43dce67648fbd8215b0723b896ba8d3d 254 SUPERFAMILY SSF53335 30 225 2.89E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS05220 43dce67648fbd8215b0723b896ba8d3d 254 Pfam PF13649 Methyltransferase domain 71 166 1.1E-19 T 28-03-2018 SMD44_RS05220 43dce67648fbd8215b0723b896ba8d3d 254 Gene3D G3DSA:3.40.50.150 20 192 4.8E-37 T 28-03-2018 SMD44_RS17320 a720f01e357b6238d1714c3b73be2ca0 499 Pfam PF00999 Sodium/hydrogen exchanger family 15 383 2.6E-49 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD44_RS17320 a720f01e357b6238d1714c3b73be2ca0 499 SUPERFAMILY SSF116726 409 478 1.57E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS17320 a720f01e357b6238d1714c3b73be2ca0 499 Pfam PF02080 TrkA-C domain 414 469 2.1E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS17320 a720f01e357b6238d1714c3b73be2ca0 499 Gene3D G3DSA:3.30.70.1450 408 487 1.9E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD44_RS33135 023a19e94ba6181dc8fa0528a9052682 533 Pfam PF17482 Phage tail sheath C-terminal domain 416 522 8.6E-21 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain SMD44_RS33135 023a19e94ba6181dc8fa0528a9052682 533 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 249 415 3.2E-41 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain SMD44_RS10760 b9429435d4ed530588e4da99e042d8fd 260 Pfam PF13462 Thioredoxin 83 256 6.3E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS10760 b9429435d4ed530588e4da99e042d8fd 260 Gene3D G3DSA:3.40.30.10 80 260 5.6E-35 T 28-03-2018 SMD44_RS10760 b9429435d4ed530588e4da99e042d8fd 260 SUPERFAMILY SSF52833 83 258 5.87E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS20980 f4213dd34861b6cd2b59b299cafbd98b 199 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 29.949 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD44_RS20980 f4213dd34861b6cd2b59b299cafbd98b 199 Gene3D G3DSA:2.40.50.140 1 120 4.5E-41 T 28-03-2018 SMD44_RS20980 f4213dd34861b6cd2b59b299cafbd98b 199 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 126 5.6E-29 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD44_RS20980 f4213dd34861b6cd2b59b299cafbd98b 199 Pfam PF00436 Single-strand binding protein family 7 107 1.1E-29 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SMD44_RS20980 f4213dd34861b6cd2b59b299cafbd98b 199 SUPERFAMILY SSF50249 6 199 3.18E-41 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS21025 f06ea23f6093faf6a9cd1d43f68b0e13 418 Gene3D G3DSA:1.20.1250.20 9 211 2.3E-15 T 28-03-2018 SMD44_RS21025 f06ea23f6093faf6a9cd1d43f68b0e13 418 Gene3D G3DSA:1.20.1250.20 222 417 2.5E-11 T 28-03-2018 SMD44_RS21025 f06ea23f6093faf6a9cd1d43f68b0e13 418 SUPERFAMILY SSF103473 22 412 6.41E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS21025 f06ea23f6093faf6a9cd1d43f68b0e13 418 Pfam PF07690 Major Facilitator Superfamily 44 378 4.0E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS09825 8f87d5e092580f66829ff68ed32b0220 313 SUPERFAMILY SSF51569 12 304 1.78E-65 T 28-03-2018 SMD44_RS09825 8f87d5e092580f66829ff68ed32b0220 313 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 12 306 44.21 T 28-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 SMD44_RS09825 8f87d5e092580f66829ff68ed32b0220 313 Pfam PF00701 Dihydrodipicolinate synthetase family 16 303 1.4E-52 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09825 8f87d5e092580f66829ff68ed32b0220 313 SMART SM01130 12 305 5.3E-75 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS09825 8f87d5e092580f66829ff68ed32b0220 313 Gene3D G3DSA:3.20.20.70 12 308 6.9E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS09825 8f87d5e092580f66829ff68ed32b0220 313 PIRSF PIRSF001365 11 311 9.5E-59 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMD44_RS33160 274c08cec428f0edebc3bc9ff5866b77 231 Pfam PF14065 Protein of unknown function (DUF4255) 4 181 2.6E-46 T 28-03-2018 IPR025351 Protein of unknown function DUF4255 SMD44_RS38330 47c37db058a0e2e409d650000b3acf2d 325 Pfam PF00107 Zinc-binding dehydrogenase 144 264 1.1E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS38330 47c37db058a0e2e409d650000b3acf2d 325 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 133 154 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD44_RS38330 47c37db058a0e2e409d650000b3acf2d 325 Gene3D G3DSA:3.90.180.10 1 127 1.2E-31 T 28-03-2018 SMD44_RS38330 47c37db058a0e2e409d650000b3acf2d 325 SUPERFAMILY SSF51735 105 260 1.38E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS38330 47c37db058a0e2e409d650000b3acf2d 325 SUPERFAMILY SSF50129 1 133 1.32E-32 T 28-03-2018 IPR011032 GroES-like SMD44_RS38330 47c37db058a0e2e409d650000b3acf2d 325 Gene3D G3DSA:3.40.50.720 128 301 2.6E-38 T 28-03-2018 SMD44_RS38330 47c37db058a0e2e409d650000b3acf2d 325 SMART SM00829 13 315 2.0E-31 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS14560 fd99f3eadcb688c615c84ecba9323970 442 SUPERFAMILY SSF52540 149 363 3.98E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14560 fd99f3eadcb688c615c84ecba9323970 442 Pfam PF01580 FtsK/SpoIIIE family 150 264 9.0E-15 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS14560 fd99f3eadcb688c615c84ecba9323970 442 Pfam PF01580 FtsK/SpoIIIE family 272 327 9.2E-7 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD44_RS14560 fd99f3eadcb688c615c84ecba9323970 442 Gene3D G3DSA:3.40.50.300 125 409 1.2E-13 T 28-03-2018 SMD44_RS10745 ddbfbe5974f08bc726fd8c79f5b210b7 411 Pfam PF02515 CoA-transferase family III 20 388 6.2E-119 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMD44_RS10745 ddbfbe5974f08bc726fd8c79f5b210b7 411 SUPERFAMILY SSF89796 18 410 7.72E-123 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS10745 ddbfbe5974f08bc726fd8c79f5b210b7 411 Gene3D G3DSA:3.40.50.10540 15 411 1.9E-133 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS22860 d07c7c879c62d86494c181b87b401878 256 Pfam PF02104 SURF1 family 19 224 5.1E-25 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 3.5E-4 T 28-03-2018 SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 Pfam PF00106 short chain dehydrogenase 9 195 4.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 Gene3D G3DSA:3.40.50.720 2 269 7.5E-54 T 28-03-2018 SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.4E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.4E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.4E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 SUPERFAMILY SSF51735 4 266 6.94E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS17215 03b5282cb7216ec3a6417fcf6a279543 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS23095 77faafe4af077153900140ffc92e3761 337 PRINTS PR00075 Fatty acid desaturase family 1 signature 282 296 1.5E-18 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD44_RS23095 77faafe4af077153900140ffc92e3761 337 PRINTS PR00075 Fatty acid desaturase family 1 signature 77 99 1.5E-18 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD44_RS23095 77faafe4af077153900140ffc92e3761 337 PRINTS PR00075 Fatty acid desaturase family 1 signature 100 120 1.5E-18 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD44_RS23095 77faafe4af077153900140ffc92e3761 337 PRINTS PR00075 Fatty acid desaturase family 1 signature 237 258 1.5E-18 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD44_RS23095 77faafe4af077153900140ffc92e3761 337 Pfam PF00487 Fatty acid desaturase 83 295 6.6E-16 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SMD44_RS11575 731d9f796d212bfbdf6d3aab0476c7de 162 Pfam PF00583 Acetyltransferase (GNAT) family 32 136 1.7E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS11575 731d9f796d212bfbdf6d3aab0476c7de 162 Gene3D G3DSA:3.40.630.30 2 162 5.9E-33 T 28-03-2018 SMD44_RS11575 731d9f796d212bfbdf6d3aab0476c7de 162 SUPERFAMILY SSF55729 5 162 6.86E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS43035 b555a1b69ba622a8f66d2da8c53dcd0d 236 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 208 2.7E-41 T 28-03-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 SMD44_RS43035 b555a1b69ba622a8f66d2da8c53dcd0d 236 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 207 1.3E-42 T 28-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 SMD44_RS43035 b555a1b69ba622a8f66d2da8c53dcd0d 236 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 44 2.2E-11 T 28-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal SMD44_RS09375 5807f51b7ab8a231cbed5d946179078e 507 Gene3D G3DSA:3.30.2290.10 1 243 1.1E-54 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SMD44_RS09375 5807f51b7ab8a231cbed5d946179078e 507 SUPERFAMILY SSF111283 13 498 6.93E-97 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMD44_RS09375 5807f51b7ab8a231cbed5d946179078e 507 Pfam PF01523 Putative modulator of DNA gyrase 32 347 1.1E-54 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMD44_RS19765 b71787dff0a4349225593d83cbab999f 155 SMART SM00347 19 121 2.0E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS19765 b71787dff0a4349225593d83cbab999f 155 Gene3D G3DSA:1.10.10.10 14 98 7.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19765 b71787dff0a4349225593d83cbab999f 155 Pfam PF12802 MarR family 27 83 7.8E-13 T 28-03-2018 SMD44_RS19765 b71787dff0a4349225593d83cbab999f 155 Gene3D G3DSA:1.10.287.100 99 136 8.9E-7 T 28-03-2018 SMD44_RS19765 b71787dff0a4349225593d83cbab999f 155 SUPERFAMILY SSF46785 22 137 1.62E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16625 7167b89b85717f89022fe1e6be4e569d 402 SUPERFAMILY SSF53187 324 400 1.11E-68 T 28-03-2018 SMD44_RS16625 7167b89b85717f89022fe1e6be4e569d 402 SUPERFAMILY SSF53187 11 213 1.11E-68 T 28-03-2018 SMD44_RS16625 7167b89b85717f89022fe1e6be4e569d 402 Pfam PF01546 Peptidase family M20/M25/M40 67 397 9.6E-26 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS16625 7167b89b85717f89022fe1e6be4e569d 402 Gene3D G3DSA:3.40.630.10 1 240 1.3E-31 T 28-03-2018 SMD44_RS16625 7167b89b85717f89022fe1e6be4e569d 402 Gene3D G3DSA:3.40.630.10 241 402 8.2E-22 T 28-03-2018 SMD44_RS16625 7167b89b85717f89022fe1e6be4e569d 402 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 5 395 3.9E-86 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 SMD44_RS16625 7167b89b85717f89022fe1e6be4e569d 402 PIRSF PIRSF001235 1 402 2.7E-125 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 SMD44_RS16625 7167b89b85717f89022fe1e6be4e569d 402 SUPERFAMILY SSF55031 206 315 5.76E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS28295 198393114d7206bfda89c90736739745 371 SUPERFAMILY SSF48576 24 332 4.32E-49 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS28295 198393114d7206bfda89c90736739745 371 Gene3D G3DSA:1.10.600.10 11 355 2.4E-63 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS16695 361f837986a37dd5ca76b72a1269a85c 242 Gene3D G3DSA:3.40.1050.10 45 242 7.9E-48 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS16695 361f837986a37dd5ca76b72a1269a85c 242 SMART SM00947 90 242 1.1E-34 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS16695 361f837986a37dd5ca76b72a1269a85c 242 SUPERFAMILY SSF53056 54 241 4.58E-41 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS16695 361f837986a37dd5ca76b72a1269a85c 242 Pfam PF00484 Carbonic anhydrase 98 236 3.8E-27 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD44_RS41425 f816899941a6afe38700f58bde6e2c67 156 Gene3D G3DSA:3.40.630.30 3 152 9.1E-31 T 28-03-2018 SMD44_RS41425 f816899941a6afe38700f58bde6e2c67 156 SUPERFAMILY SSF55729 8 147 2.96E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS41425 f816899941a6afe38700f58bde6e2c67 156 Pfam PF00583 Acetyltransferase (GNAT) family 39 141 5.1E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS12800 f947a3ee17fdf54be56cf88069863471 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 26 39 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS12800 f947a3ee17fdf54be56cf88069863471 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 24 170 3.9E-34 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS12800 f947a3ee17fdf54be56cf88069863471 296 Gene3D G3DSA:1.10.1040.10 187 293 2.7E-7 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS12800 f947a3ee17fdf54be56cf88069863471 296 SUPERFAMILY SSF48179 177 289 1.11E-13 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS12800 f947a3ee17fdf54be56cf88069863471 296 Gene3D G3DSA:3.40.50.720 1 186 7.0E-27 T 28-03-2018 SMD44_RS12800 f947a3ee17fdf54be56cf88069863471 296 PIRSF PIRSF000103 16 296 2.9E-60 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS12800 f947a3ee17fdf54be56cf88069863471 296 SUPERFAMILY SSF51735 22 172 1.12E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS13645 bef7ca90128090a447d6a805ffbdf47d 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 316 4.1E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13645 bef7ca90128090a447d6a805ffbdf47d 319 SUPERFAMILY SSF161098 94 299 3.92E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13645 bef7ca90128090a447d6a805ffbdf47d 319 Gene3D G3DSA:1.10.3720.10 11 317 1.5E-34 T 28-03-2018 SMD44_RS08455 bce2173461420208323f070ea5c59d44 468 Pfam PF02447 GntP family permease 27 467 2.5E-141 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD44_RS08455 bce2173461420208323f070ea5c59d44 468 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 27 468 2.7E-137 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD44_RS08455 bce2173461420208323f070ea5c59d44 468 PIRSF PIRSF002746 20 468 6.0E-141 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD44_RS03125 3a1cf9074eae504f97e83bd411deeb2f 413 Gene3D G3DSA:3.30.470.20 124 405 2.6E-36 T 28-03-2018 SMD44_RS03125 3a1cf9074eae504f97e83bd411deeb2f 413 Gene3D G3DSA:3.40.50.20 25 123 1.7E-5 T 28-03-2018 SMD44_RS03125 3a1cf9074eae504f97e83bd411deeb2f 413 SUPERFAMILY SSF56059 106 323 4.07E-39 T 28-03-2018 SMD44_RS03125 3a1cf9074eae504f97e83bd411deeb2f 413 Pfam PF07478 D-ala D-ala ligase C-terminus 128 284 2.1E-8 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS10820 895acaa74822e741aef1212aab35f3b0 413 Gene3D G3DSA:1.20.1250.20 223 410 3.5E-9 T 28-03-2018 SMD44_RS10820 895acaa74822e741aef1212aab35f3b0 413 Gene3D G3DSA:1.20.1250.20 16 210 9.3E-18 T 28-03-2018 SMD44_RS10820 895acaa74822e741aef1212aab35f3b0 413 SUPERFAMILY SSF103473 20 407 8.11E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS10820 895acaa74822e741aef1212aab35f3b0 413 Pfam PF07690 Major Facilitator Superfamily 27 248 5.2E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS17780 0695f18c851b09f101de8d738c17567d 392 Pfam PF13560 Helix-turn-helix domain 4 61 1.7E-11 T 28-03-2018 SMD44_RS17780 0695f18c851b09f101de8d738c17567d 392 Gene3D G3DSA:1.25.40.10 68 364 3.8E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS17780 0695f18c851b09f101de8d738c17567d 392 Gene3D G3DSA:1.10.260.40 1 67 1.1E-15 T 28-03-2018 SMD44_RS17780 0695f18c851b09f101de8d738c17567d 392 SUPERFAMILY SSF47413 2 63 2.95E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS17780 0695f18c851b09f101de8d738c17567d 392 SMART SM00530 7 63 4.3E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS23840 b9de914e2e885f1c7ef076bf3533847e 268 Pfam PF03309 Type III pantothenate kinase 2 211 1.6E-68 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD44_RS23840 b9de914e2e885f1c7ef076bf3533847e 268 Gene3D G3DSA:3.30.420.40 94 268 4.4E-59 T 28-03-2018 SMD44_RS23840 b9de914e2e885f1c7ef076bf3533847e 268 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 261 6.7E-75 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD44_RS23840 b9de914e2e885f1c7ef076bf3533847e 268 SUPERFAMILY SSF53067 1 127 1.94E-32 T 28-03-2018 SMD44_RS23840 b9de914e2e885f1c7ef076bf3533847e 268 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 265 35.653 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD44_RS23840 b9de914e2e885f1c7ef076bf3533847e 268 SUPERFAMILY SSF53067 129 264 1.04E-35 T 28-03-2018 SMD44_RS01695 a359b39aa376d7113359dc804273eff4 220 SUPERFAMILY SSF51306 28 158 6.93E-20 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS01695 a359b39aa376d7113359dc804273eff4 220 Gene3D G3DSA:2.10.109.10 13 153 1.0E-17 T 28-03-2018 SMD44_RS01695 a359b39aa376d7113359dc804273eff4 220 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 25 41 3.3E-10 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS01695 a359b39aa376d7113359dc804273eff4 220 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 87 99 3.3E-10 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS01695 a359b39aa376d7113359dc804273eff4 220 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 115 134 3.3E-10 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS01695 a359b39aa376d7113359dc804273eff4 220 Pfam PF00717 Peptidase S24-like 31 97 7.8E-7 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS39265 43658037ad69490f793fd0c2aa090762 507 SUPERFAMILY SSF53720 14 499 6.41E-161 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS39265 43658037ad69490f793fd0c2aa090762 507 Gene3D G3DSA:3.40.309.10 279 481 6.9E-63 T 28-03-2018 SMD44_RS39265 43658037ad69490f793fd0c2aa090762 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS39265 43658037ad69490f793fd0c2aa090762 507 Gene3D G3DSA:3.40.605.10 8 278 3.9E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS39265 43658037ad69490f793fd0c2aa090762 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS39265 43658037ad69490f793fd0c2aa090762 507 Pfam PF00171 Aldehyde dehydrogenase family 32 494 1.0E-160 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS36185 0f280526deb08be76d6582a11db8376d 381 SUPERFAMILY SSF53335 177 343 6.07E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS36185 0f280526deb08be76d6582a11db8376d 381 Gene3D G3DSA:3.40.50.150 170 354 8.1E-33 T 28-03-2018 SMD44_RS36185 0f280526deb08be76d6582a11db8376d 381 Pfam PF13649 Methyltransferase domain 193 289 2.6E-15 T 28-03-2018 SMD44_RS27750 717b8c3d73e8014285e23915f7527b96 302 SUPERFAMILY SSF102588 7 295 2.62E-69 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS27750 717b8c3d73e8014285e23915f7527b96 302 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 10 295 3.7E-130 T 28-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS27750 717b8c3d73e8014285e23915f7527b96 302 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 9 295 42.116 T 28-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD44_RS27750 717b8c3d73e8014285e23915f7527b96 302 Pfam PF02585 GlcNAc-PI de-N-acetylase 10 160 1.5E-25 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD44_RS27750 717b8c3d73e8014285e23915f7527b96 302 Gene3D G3DSA:3.40.50.10320 3 302 5.8E-77 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS27845 ffabd37adcfc2a789c4311853d66fb4c 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 264 3.8E-54 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS27845 ffabd37adcfc2a789c4311853d66fb4c 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD44_RS27845 ffabd37adcfc2a789c4311853d66fb4c 266 Gene3D G3DSA:1.10.12.10 225 266 2.0E-12 T 28-03-2018 IPR014748 Crontonase, C-terminal SMD44_RS27845 ffabd37adcfc2a789c4311853d66fb4c 266 SUPERFAMILY SSF52096 2 265 1.23E-76 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS27845 ffabd37adcfc2a789c4311853d66fb4c 266 Gene3D G3DSA:3.90.226.10 4 224 4.6E-60 T 28-03-2018 SMD44_RS32435 82f5a38674ed84536d73e94c47066629 255 Pfam PF13628 Domain of unknown function (DUF4142) 54 184 5.5E-18 T 28-03-2018 IPR025419 Domain of unknown function DUF4142 SMD44_RS32435 82f5a38674ed84536d73e94c47066629 255 Gene3D G3DSA:1.20.1260.10 43 189 5.0E-14 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS00620 52ec7019058ed4058eb763ef25f7bbd4 346 SUPERFAMILY SSF56281 1 149 3.97E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS00620 52ec7019058ed4058eb763ef25f7bbd4 346 SUPERFAMILY SSF56281 206 300 3.97E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS00620 52ec7019058ed4058eb763ef25f7bbd4 346 Gene3D G3DSA:3.60.15.10 8 337 1.5E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS25620 ffd3dec81afb81d0a38d164adb6bf337 73 SUPERFAMILY SSF50249 4 72 9.3E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS25620 ffd3dec81afb81d0a38d164adb6bf337 73 SMART SM00316 5 73 3.8E-5 T 28-03-2018 IPR022967 RNA-binding domain, S1 SMD44_RS25620 ffd3dec81afb81d0a38d164adb6bf337 73 Gene3D G3DSA:2.40.50.140 1 73 1.4E-37 T 28-03-2018 SMD44_RS25620 ffd3dec81afb81d0a38d164adb6bf337 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.839 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SMD44_RS25620 ffd3dec81afb81d0a38d164adb6bf337 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.9E-29 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 SMD44_RS25620 ffd3dec81afb81d0a38d164adb6bf337 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 3.5E-38 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 Gene3D G3DSA:2.60.120.280 19 208 2.8E-16 T 28-03-2018 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 278 320 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 Gene3D G3DSA:1.10.10.60 209 253 1.7E-5 T 28-03-2018 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 SUPERFAMILY SSF46689 224 274 6.81E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 Pfam PF12833 Helix-turn-helix domain 247 326 1.4E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 SUPERFAMILY SSF46689 277 328 6.27E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 Pfam PF12852 Cupin 2 208 4.9E-47 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 Gene3D G3DSA:1.10.260.40 254 290 0.0063 T 28-03-2018 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 SMART SM00342 241 324 3.4E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS18410 5cb2c92c54d657606580521df88bd4da 347 Gene3D G3DSA:1.10.10.60 291 330 4.8E-17 T 28-03-2018 SMD44_RS31925 b95f8b06e92884b46a53f4ce863104e4 118 SUPERFAMILY SSF46785 4 84 4.48E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31925 b95f8b06e92884b46a53f4ce863104e4 118 SMART SM00418 8 95 4.4E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS31925 b95f8b06e92884b46a53f4ce863104e4 118 Gene3D G3DSA:1.10.10.10 1 86 2.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31925 b95f8b06e92884b46a53f4ce863104e4 118 Pfam PF01022 Bacterial regulatory protein, arsR family 17 59 4.2E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS36500 7f3659c5f2b194cc3f655ee76e213d8b 343 Gene3D G3DSA:3.40.366.10 1 284 6.3E-27 T 28-03-2018 SMD44_RS36500 7f3659c5f2b194cc3f655ee76e213d8b 343 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 290 3.4E-6 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMD44_RS36500 7f3659c5f2b194cc3f655ee76e213d8b 343 Pfam PF00698 Acyl transferase domain 1 86 1.9E-24 T 28-03-2018 IPR014043 Acyl transferase SMD44_RS36500 7f3659c5f2b194cc3f655ee76e213d8b 343 SUPERFAMILY SSF52151 1 87 1.86E-19 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD44_RS18475 ed7354ef2bd11f793dade029887ed680 487 Gene3D G3DSA:1.10.260.40 10 95 7.2E-6 T 28-03-2018 SMD44_RS18475 ed7354ef2bd11f793dade029887ed680 487 Pfam PF13560 Helix-turn-helix domain 15 78 2.3E-8 T 28-03-2018 SMD44_RS18475 ed7354ef2bd11f793dade029887ed680 487 SUPERFAMILY SSF47413 19 86 1.73E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS10620 ef179b2b5b54c78668484d6145df7777 1038 Gene3D G3DSA:2.60.120.260 869 1038 1.6E-50 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS10620 ef179b2b5b54c78668484d6145df7777 1038 Gene3D G3DSA:2.60.120.260 712 864 4.6E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS10620 ef179b2b5b54c78668484d6145df7777 1038 Gene3D G3DSA:2.70.98.10 55 305 1.3E-87 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMD44_RS10620 ef179b2b5b54c78668484d6145df7777 1038 Pfam PF17451 Glycosyl hydrolase 101 beta sandwich domain 574 676 2.5E-27 T 28-03-2018 IPR035364 Glycosyl hydrolase 101, beta-sandwich domain SMD44_RS10620 ef179b2b5b54c78668484d6145df7777 1038 Gene3D G3DSA:2.60.40.1180 578 703 1.1E-44 T 28-03-2018 SMD44_RS10620 ef179b2b5b54c78668484d6145df7777 1038 Pfam PF12905 Endo-alpha-N-acetylgalactosaminidase 295 568 7.4E-125 T 28-03-2018 IPR025706 Endo-alpha-N-acetylgalactosaminidase GO:0033926 SMD44_RS10620 ef179b2b5b54c78668484d6145df7777 1038 Gene3D G3DSA:3.20.20.80 308 577 4.2E-106 T 28-03-2018 SMD44_RS09870 8a4dd82844ac64d10581dad269ffd5ab 409 Gene3D G3DSA:2.60.60.30 245 402 3.7E-42 T 28-03-2018 SMD44_RS09870 8a4dd82844ac64d10581dad269ffd5ab 409 Gene3D G3DSA:2.60.60.30 8 157 5.1E-32 T 28-03-2018 SMD44_RS09870 8a4dd82844ac64d10581dad269ffd5ab 409 Pfam PF02342 TerD domain 227 395 5.1E-40 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS09870 8a4dd82844ac64d10581dad269ffd5ab 409 Pfam PF02342 TerD domain 20 158 4.5E-27 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS30520 65ce0c8f6fa5a5f425df9f065b28d158 170 Pfam PF00293 NUDIX domain 13 137 6.5E-21 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS30520 65ce0c8f6fa5a5f425df9f065b28d158 170 PRINTS PR00502 NUDIX hydrolase family signature 44 58 5.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS30520 65ce0c8f6fa5a5f425df9f065b28d158 170 PRINTS PR00502 NUDIX hydrolase family signature 58 73 5.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD44_RS30520 65ce0c8f6fa5a5f425df9f065b28d158 170 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS30520 65ce0c8f6fa5a5f425df9f065b28d158 170 Gene3D G3DSA:3.90.79.10 5 166 5.6E-24 T 28-03-2018 SMD44_RS30520 65ce0c8f6fa5a5f425df9f065b28d158 170 SUPERFAMILY SSF55811 12 155 2.98E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS01760 38a4c4bf0dde00e807ed616a3586954b 201 Pfam PF13560 Helix-turn-helix domain 12 70 3.1E-16 T 28-03-2018 SMD44_RS01760 38a4c4bf0dde00e807ed616a3586954b 201 Gene3D G3DSA:1.10.260.40 4 66 5.9E-21 T 28-03-2018 SMD44_RS01760 38a4c4bf0dde00e807ed616a3586954b 201 SMART SM00530 15 70 1.1E-18 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS01760 38a4c4bf0dde00e807ed616a3586954b 201 SUPERFAMILY SSF47413 7 75 1.3E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS01760 38a4c4bf0dde00e807ed616a3586954b 201 Pfam PF07883 Cupin domain 119 177 9.3E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS01760 38a4c4bf0dde00e807ed616a3586954b 201 SUPERFAMILY SSF51182 66 176 7.56E-21 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS01760 38a4c4bf0dde00e807ed616a3586954b 201 Gene3D G3DSA:2.60.120.10 67 194 2.1E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS10810 56b3429964eddb3cd1ef1d120fa34cfd 211 SUPERFAMILY SSF109854 12 114 1.1E-6 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS10810 56b3429964eddb3cd1ef1d120fa34cfd 211 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 204 3.5E-81 T 28-03-2018 IPR017519 Conserved hypothetical protein CHP03085 SMD44_RS10810 56b3429964eddb3cd1ef1d120fa34cfd 211 Gene3D G3DSA:1.20.120.450 1 179 1.1E-21 T 28-03-2018 SMD44_RS10810 56b3429964eddb3cd1ef1d120fa34cfd 211 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 141 4.6E-6 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS10810 56b3429964eddb3cd1ef1d120fa34cfd 211 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 185 3.6E-40 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD44_RS14685 f4101abbd4e249ae3d7ddd3c5051f2ee 529 Pfam PF12450 von Willebrand factor 61 122 7.4E-18 T 28-03-2018 IPR022156 Uncharacterised protein YfbK, N-terminal SMD44_RS14685 f4101abbd4e249ae3d7ddd3c5051f2ee 529 SMART SM00327 148 325 3.9E-26 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS14685 f4101abbd4e249ae3d7ddd3c5051f2ee 529 Pfam PF00092 von Willebrand factor type A domain 151 320 3.8E-23 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS14685 f4101abbd4e249ae3d7ddd3c5051f2ee 529 SUPERFAMILY SSF53300 146 321 4.84E-34 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS14685 f4101abbd4e249ae3d7ddd3c5051f2ee 529 Gene3D G3DSA:3.40.50.410 137 325 1.1E-33 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS14685 f4101abbd4e249ae3d7ddd3c5051f2ee 529 Pfam PF12034 Domain of unknown function (DUF3520) 333 453 1.5E-23 T 28-03-2018 IPR021908 Protein of unknown function DUF3520 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Gene3D G3DSA:2.150.10.10 21 202 1.8E-6 T 28-03-2018 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Gene3D G3DSA:2.150.10.10 203 279 1.5E-19 T 28-03-2018 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 PRINTS PR00313 NodO calcium binding signature 235 243 1.5E-10 T 28-03-2018 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 PRINTS PR00313 NodO calcium binding signature 180 191 1.5E-10 T 28-03-2018 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 PRINTS PR00313 NodO calcium binding signature 199 207 1.5E-10 T 28-03-2018 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 PRINTS PR00313 NodO calcium binding signature 262 271 1.5E-10 T 28-03-2018 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 249 267 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 SUPERFAMILY SSF51120 182 276 6.54E-21 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 SUPERFAMILY SSF51120 113 192 6.54E-5 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 234 251 3.3E-5 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 182 190 2.3 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 216 233 0.0082 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 198 209 31.0 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 162 175 50.0 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 252 269 0.0066 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMD44_RS17965 ae86df1374403d3ac19da64a237088ca 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 145 157 5.2 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMD44_RS04820 a5d76c90c9621afe83d66093c7cf55ac 232 Pfam PF08281 Sigma-70, region 4 157 207 1.7E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS04820 a5d76c90c9621afe83d66093c7cf55ac 232 SUPERFAMILY SSF88946 52 132 5.89E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS04820 a5d76c90c9621afe83d66093c7cf55ac 232 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 56 210 6.6E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS04820 a5d76c90c9621afe83d66093c7cf55ac 232 Pfam PF04542 Sigma-70 region 2 60 127 1.2E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS04820 a5d76c90c9621afe83d66093c7cf55ac 232 SUPERFAMILY SSF88659 152 211 1.7E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS04820 a5d76c90c9621afe83d66093c7cf55ac 232 Gene3D G3DSA:1.10.1740.10 44 130 1.4E-14 T 28-03-2018 SMD44_RS04820 a5d76c90c9621afe83d66093c7cf55ac 232 Gene3D G3DSA:1.10.10.10 155 230 2.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09820 f88a7152e0136c2230ec45906f8929c5 388 Gene3D G3DSA:3.20.20.70 17 225 4.8E-8 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS02475 23ae9fb179093190260c672751cb213e 275 SUPERFAMILY SSF53335 2 273 4.85E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS02475 23ae9fb179093190260c672751cb213e 275 Gene3D G3DSA:3.40.50.150 35 275 4.2E-35 T 28-03-2018 SMD44_RS02475 23ae9fb179093190260c672751cb213e 275 Pfam PF08241 Methyltransferase domain 67 165 2.8E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS05105 f27fa177136c75489ed11723d85dac1b 240 Gene3D G3DSA:1.10.357.10 55 237 4.9E-28 T 28-03-2018 SMD44_RS05105 f27fa177136c75489ed11723d85dac1b 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 67 113 7.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS05105 f27fa177136c75489ed11723d85dac1b 240 SUPERFAMILY SSF46689 55 135 9.23E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00680 54ae93c19e548258330f3030b04a03a7 194 Pfam PF04978 Protein of unknown function (DUF664) 10 158 9.3E-44 T 28-03-2018 IPR007061 Protein of unknown function DUF664 SMD44_RS00680 54ae93c19e548258330f3030b04a03a7 194 Gene3D G3DSA:1.20.120.450 6 185 1.6E-29 T 28-03-2018 SMD44_RS00680 54ae93c19e548258330f3030b04a03a7 194 SUPERFAMILY SSF109854 8 157 3.51E-35 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS13615 31fe83e0e4f2484c4e63811cccdb14fa 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 7.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS13615 31fe83e0e4f2484c4e63811cccdb14fa 191 Gene3D G3DSA:1.10.260.40 40 67 1.9E-11 T 28-03-2018 SMD44_RS13615 31fe83e0e4f2484c4e63811cccdb14fa 191 SUPERFAMILY SSF46689 4 82 4.27E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS13615 31fe83e0e4f2484c4e63811cccdb14fa 191 Gene3D G3DSA:1.10.10.60 1 39 1.8E-14 T 28-03-2018 SMD44_RS13615 31fe83e0e4f2484c4e63811cccdb14fa 191 Gene3D G3DSA:1.10.357.10 68 186 3.7E-8 T 28-03-2018 SMD44_RS10690 6be80dbb7a02dc575d4106e05953b161 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 264 6.3E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS10690 6be80dbb7a02dc575d4106e05953b161 277 Gene3D G3DSA:1.10.3720.10 1 264 8.5E-47 T 28-03-2018 SMD44_RS10690 6be80dbb7a02dc575d4106e05953b161 277 SUPERFAMILY SSF161098 7 277 7.29E-70 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS41140 3bcb5a990f432ce24171aded42049f47 101 SUPERFAMILY SSF46785 5 97 6.18E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS41140 3bcb5a990f432ce24171aded42049f47 101 Pfam PF03551 Transcriptional regulator PadR-like family 9 80 2.2E-23 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS41140 3bcb5a990f432ce24171aded42049f47 101 Gene3D G3DSA:1.10.10.10 1 92 3.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13960 65d20357d3cab43895c2963440827a5a 377 Gene3D G3DSA:3.30.2010.10 72 162 4.4E-18 T 28-03-2018 SMD44_RS13960 65d20357d3cab43895c2963440827a5a 377 Pfam PF01435 Peptidase family M48 81 275 8.5E-25 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD44_RS34160 97f64d924b4beece82de52b65c778eb1 373 Gene3D G3DSA:3.90.1510.10 40 274 1.4E-87 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 SMD44_RS34160 97f64d924b4beece82de52b65c778eb1 373 SUPERFAMILY SSF110738 1 369 1.44E-114 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD44_RS34160 97f64d924b4beece82de52b65c778eb1 373 PIRSF PIRSF006078 1 373 2.5E-119 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD44_RS34160 97f64d924b4beece82de52b65c778eb1 373 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 1 369 1.0E-118 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD44_RS34160 97f64d924b4beece82de52b65c778eb1 373 Pfam PF02595 Glycerate kinase family 1 369 2.2E-129 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD44_RS18050 2d57a3f4b1d73b9a2cf471e70f712139 190 SUPERFAMILY SSF55729 9 175 1.95E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS18050 2d57a3f4b1d73b9a2cf471e70f712139 190 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 1.2E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS18050 2d57a3f4b1d73b9a2cf471e70f712139 190 Gene3D G3DSA:3.40.630.30 4 183 1.3E-29 T 28-03-2018 SMD44_RS36580 38b7aa759436b09673dfe4cafbc7524e 264 Pfam PF01925 Sulfite exporter TauE/SafE 22 260 2.5E-24 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 Pfam PF02881 SRP54-type protein, helical bundle domain 120 185 4.8E-13 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 SMART SM00962 206 405 1.1E-104 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 378 391 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 Pfam PF00448 SRP54-type protein, GTPase domain 207 404 6.6E-73 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 Gene3D G3DSA:1.20.120.140 96 187 1.6E-19 T 28-03-2018 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 SMART SM00963 109 189 2.3E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 Gene3D G3DSA:3.40.50.300 202 406 1.4E-38 T 28-03-2018 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 SUPERFAMILY SSF47364 105 183 1.1E-18 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 SMART SM00382 205 355 3.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 SUPERFAMILY SSF52540 204 404 1.46E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 132 405 58.443 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SMD44_RS30415 804d8e37d2187803aefdf257cceb66b0 406 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 133 403 5.6E-102 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SMD44_RS22785 d18d017ca45b59a1a0e1732cea125db3 365 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 139 355 3.2E-10 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS22785 d18d017ca45b59a1a0e1732cea125db3 365 Gene3D G3DSA:3.60.10.10 127 363 3.3E-22 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS22785 d18d017ca45b59a1a0e1732cea125db3 365 SUPERFAMILY SSF56219 133 363 1.23E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS15545 b4b0887fe640aed729d42ffe2a144800 459 Pfam PF04286 Protein of unknown function (DUF445) 94 455 4.1E-103 T 28-03-2018 IPR007383 Protein of unknown function DUF445 SMD44_RS02975 571ace609d1dbba47743713aa47848a9 216 Pfam PF07336 Putative stress-induced transcription regulator 27 154 1.7E-19 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS02975 571ace609d1dbba47743713aa47848a9 216 SUPERFAMILY SSF160904 21 200 5.36E-42 T 28-03-2018 SMD44_RS02975 571ace609d1dbba47743713aa47848a9 216 Gene3D G3DSA:1.10.3300.10 17 203 4.2E-46 T 28-03-2018 IPR023286 ABATE domain SMD44_RS02975 571ace609d1dbba47743713aa47848a9 216 Pfam PF11706 CGNR zinc finger 158 201 3.5E-19 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS11690 c111e1f384b5ad4b62c432a8843668c3 249 Pfam PF13847 Methyltransferase domain 76 206 3.7E-26 T 28-03-2018 IPR025714 Methyltransferase domain SMD44_RS11690 c111e1f384b5ad4b62c432a8843668c3 249 Gene3D G3DSA:3.40.50.150 2 246 9.0E-36 T 28-03-2018 SMD44_RS11690 c111e1f384b5ad4b62c432a8843668c3 249 SUPERFAMILY SSF53335 63 229 3.2E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS06240 a1c8d475a7b69ea8d5a0228530db1fe1 284 Gene3D G3DSA:3.40.630.30 39 179 9.0E-34 T 28-03-2018 SMD44_RS06240 a1c8d475a7b69ea8d5a0228530db1fe1 284 SUPERFAMILY SSF55729 38 245 5.82E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS06240 a1c8d475a7b69ea8d5a0228530db1fe1 284 Pfam PF13444 Acetyltransferase (GNAT) domain 56 153 7.6E-29 T 28-03-2018 SMD44_RS22370 02b41f45cb5b0a8ce0414b8a4b46e111 245 Pfam PF07702 UTRA domain 101 236 2.0E-19 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS22370 02b41f45cb5b0a8ce0414b8a4b46e111 245 SMART SM00866 97 237 3.5E-11 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS22370 02b41f45cb5b0a8ce0414b8a4b46e111 245 Gene3D G3DSA:1.10.10.10 5 81 3.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22370 02b41f45cb5b0a8ce0414b8a4b46e111 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 2.7E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS22370 02b41f45cb5b0a8ce0414b8a4b46e111 245 SUPERFAMILY SSF64288 61 236 2.67E-23 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS22370 02b41f45cb5b0a8ce0414b8a4b46e111 245 SMART SM00345 14 73 9.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS22370 02b41f45cb5b0a8ce0414b8a4b46e111 245 Gene3D G3DSA:3.40.1410.10 94 236 1.8E-25 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS22370 02b41f45cb5b0a8ce0414b8a4b46e111 245 SUPERFAMILY SSF46785 1 86 5.17E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15145 47280bf56466f8688189d77e81cf9106 408 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 74 337 5.8E-56 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD44_RS35990 e99422abf6b3be8110b3841701da96f7 199 SUPERFAMILY SSF47413 20 86 2.73E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS35990 e99422abf6b3be8110b3841701da96f7 199 Gene3D G3DSA:1.10.260.40 13 88 4.0E-18 T 28-03-2018 SMD44_RS35990 e99422abf6b3be8110b3841701da96f7 199 SUPERFAMILY SSF51182 66 195 5.94E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS35990 e99422abf6b3be8110b3841701da96f7 199 Gene3D G3DSA:2.60.120.10 89 199 2.0E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS35990 e99422abf6b3be8110b3841701da96f7 199 SMART SM00530 25 80 2.6E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS35990 e99422abf6b3be8110b3841701da96f7 199 Pfam PF07883 Cupin domain 142 195 1.3E-6 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS35990 e99422abf6b3be8110b3841701da96f7 199 Pfam PF13560 Helix-turn-helix domain 21 78 4.3E-14 T 28-03-2018 SMD44_RS16540 49dfa2c8a021d1a27b194585bb5e2fb7 396 SUPERFAMILY SSF51556 6 254 1.17E-102 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS16540 49dfa2c8a021d1a27b194585bb5e2fb7 396 SUPERFAMILY SSF51556 294 382 1.17E-102 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS16540 49dfa2c8a021d1a27b194585bb5e2fb7 396 Gene3D G3DSA:3.20.20.140 4 396 8.3E-143 T 28-03-2018 SMD44_RS16540 49dfa2c8a021d1a27b194585bb5e2fb7 396 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 12 371 6.0E-116 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 SUPERFAMILY SSF51735 10 256 3.9E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 3.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 3.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 3.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 3.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 Gene3D G3DSA:3.40.50.720 46 258 4.1E-63 T 28-03-2018 SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 Gene3D G3DSA:3.40.50.720 3 45 8.6E-11 T 28-03-2018 SMD44_RS31165 b72039a040657e71292a31876d74aa75 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 254 2.0E-66 T 28-03-2018 SMD44_RS07290 c82657b3bc055f0062374d9cb901b572 143 SUPERFAMILY SSF48013 4 132 1.57E-39 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD44_RS07290 c82657b3bc055f0062374d9cb901b572 143 Pfam PF01029 NusB family 6 132 1.2E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD44_RS07290 c82657b3bc055f0062374d9cb901b572 143 Gene3D G3DSA:1.10.940.10 1 132 3.9E-41 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD44_RS07290 c82657b3bc055f0062374d9cb901b572 143 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 133 3.3E-39 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 SMD44_RS07290 c82657b3bc055f0062374d9cb901b572 143 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 137 22.233 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 SMD44_RS11170 34b8c2f73e99cddd73d50df04d467f67 264 Gene3D G3DSA:3.20.20.70 3 261 9.7E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS11170 34b8c2f73e99cddd73d50df04d467f67 264 Hamap MF_00443 Thiazole synthase [thiG]. 5 256 42.311 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 SMD44_RS11170 34b8c2f73e99cddd73d50df04d467f67 264 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 250 2.5E-104 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 SMD44_RS11170 34b8c2f73e99cddd73d50df04d467f67 264 SUPERFAMILY SSF110399 4 242 6.28E-81 T 28-03-2018 SMD44_RS09660 150dc49ecf731338d0b1e4e104983e4b 201 Gene3D G3DSA:3.40.50.10230 1 191 3.6E-62 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMD44_RS09660 150dc49ecf731338d0b1e4e104983e4b 201 SUPERFAMILY SSF63965 6 187 4.19E-53 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMD44_RS09660 150dc49ecf731338d0b1e4e104983e4b 201 Pfam PF02570 Precorrin-8X methylmutase 8 186 1.4E-53 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMD44_RS25525 9468d6f8d05f0bc90ecce93fddeaa2df 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 111 30.034 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25525 9468d6f8d05f0bc90ecce93fddeaa2df 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD44_RS25525 9468d6f8d05f0bc90ecce93fddeaa2df 115 Gene3D G3DSA:3.90.470.10 1 115 6.9E-45 T 28-03-2018 SMD44_RS25525 9468d6f8d05f0bc90ecce93fddeaa2df 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 108 1.3E-44 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS25525 9468d6f8d05f0bc90ecce93fddeaa2df 115 Pfam PF00237 Ribosomal protein L22p/L17e 5 108 2.8E-36 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SMD44_RS25525 9468d6f8d05f0bc90ecce93fddeaa2df 115 SUPERFAMILY SSF54843 1 112 4.71E-42 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SMD44_RS15920 076817d858acb6b4e4edcacbced12e76 189 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 8 186 26.744 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 SMD44_RS15920 076817d858acb6b4e4edcacbced12e76 189 Gene3D G3DSA:3.40.1740.10 1 87 3.4E-19 T 28-03-2018 SMD44_RS15920 076817d858acb6b4e4edcacbced12e76 189 Gene3D G3DSA:3.40.1740.10 117 178 2.4E-9 T 28-03-2018 SMD44_RS15920 076817d858acb6b4e4edcacbced12e76 189 SUPERFAMILY SSF143456 4 183 1.23E-47 T 28-03-2018 SMD44_RS15920 076817d858acb6b4e4edcacbced12e76 189 Pfam PF02622 Uncharacterized ACR, COG1678 19 172 4.2E-35 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 SMD44_RS08115 50b3edec2a49af470a2bb411d16fb84c 124 SUPERFAMILY SSF54534 15 124 3.34E-40 T 28-03-2018 SMD44_RS08115 50b3edec2a49af470a2bb411d16fb84c 124 Gene3D G3DSA:3.10.50.40 4 124 5.9E-41 T 28-03-2018 SMD44_RS08115 50b3edec2a49af470a2bb411d16fb84c 124 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 31 121 3.1E-31 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SMD44_RS36870 9f54886c6d1bc0e83002235725b44f21 269 SMART SM00823 Phosphopantetheine attachment site 114 186 1.7E-32 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD44_RS36870 9f54886c6d1bc0e83002235725b44f21 269 Gene3D G3DSA:1.10.1200.10 73 195 7.4E-21 T 28-03-2018 SMD44_RS36870 9f54886c6d1bc0e83002235725b44f21 269 SUPERFAMILY SSF47336 112 192 3.53E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36870 9f54886c6d1bc0e83002235725b44f21 269 SMART SM01294 115 182 3.8E-7 T 28-03-2018 SMD44_RS36870 9f54886c6d1bc0e83002235725b44f21 269 Pfam PF00550 Phosphopantetheine attachment site 117 182 1.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS36870 9f54886c6d1bc0e83002235725b44f21 269 ProSitePatterns PS00012 Phosphopantetheine attachment site. 141 156 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 SMART SM00421 147 209 3.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 Gene3D G3DSA:3.40.50.2300 1 131 1.2E-29 T 28-03-2018 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 SUPERFAMILY SSF52172 2 131 4.7E-22 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 SUPERFAMILY SSF46894 136 194 5.78E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 SMART SM00448 1 120 9.1E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 194 1.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 Pfam PF00072 Response regulator receiver domain 3 107 1.9E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS16160 1b2d39c13d2c899bb990aac334fcda0b 214 Gene3D G3DSA:1.10.10.10 132 214 7.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19130 c73237c91c607b460ea681c6291e8fb6 210 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 1 188 9.0E-41 T 28-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 SMD44_RS19130 c73237c91c607b460ea681c6291e8fb6 210 Gene3D G3DSA:3.40.50.1000 68 209 1.2E-16 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS19130 c73237c91c607b460ea681c6291e8fb6 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 85 177 2.7E-8 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS19130 c73237c91c607b460ea681c6291e8fb6 210 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 2 172 1.8E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS19130 c73237c91c607b460ea681c6291e8fb6 210 SUPERFAMILY SSF56784 1 208 3.83E-36 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS15465 b786054ab7d98de601ac5343cecdc520 521 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 423 443 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 SMD44_RS15465 b786054ab7d98de601ac5343cecdc520 521 Pfam PF00474 Sodium:solute symporter family 46 441 3.8E-17 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS16500 1cb1105fd5e1f1df1045a878d693a722 180 SUPERFAMILY SSF54637 18 173 2.3E-43 T 28-03-2018 IPR029069 HotDog domain SMD44_RS16500 1cb1105fd5e1f1df1045a878d693a722 180 Gene3D G3DSA:3.10.129.10 15 169 1.1E-50 T 28-03-2018 SMD44_RS16500 1cb1105fd5e1f1df1045a878d693a722 180 Pfam PF03061 Thioesterase superfamily 38 108 2.5E-20 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMD44_RS09185 210b4a377a3ab54c170c74c7b43e30fd 265 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS09185 210b4a377a3ab54c170c74c7b43e30fd 265 SUPERFAMILY SSF52540 4 229 1.63E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09185 210b4a377a3ab54c170c74c7b43e30fd 265 Gene3D G3DSA:3.40.50.300 2 246 8.4E-59 T 28-03-2018 SMD44_RS09185 210b4a377a3ab54c170c74c7b43e30fd 265 Pfam PF00005 ABC transporter 21 167 1.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS09185 210b4a377a3ab54c170c74c7b43e30fd 265 SMART SM00382 28 217 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS36235 e9c9252ea1d60ae5e5ee9c80f2210f31 296 Gene3D G3DSA:1.10.10.10 7 282 0.011 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17355 db4e9a22afb51f2b9a127265701dd2ff 242 Gene3D G3DSA:3.80.30.10 66 242 1.3E-33 T 28-03-2018 SMD44_RS17355 db4e9a22afb51f2b9a127265701dd2ff 242 Pfam PF13353 4Fe-4S single cluster domain 14 122 2.5E-14 T 28-03-2018 SMD44_RS17355 db4e9a22afb51f2b9a127265701dd2ff 242 ProSitePatterns PS01087 Radical activating enzymes signature. 16 37 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 SMD44_RS17355 db4e9a22afb51f2b9a127265701dd2ff 242 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 5 235 9.9E-86 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 SMD44_RS17355 db4e9a22afb51f2b9a127265701dd2ff 242 SUPERFAMILY SSF102114 21 208 1.14E-24 T 28-03-2018 SMD44_RS17355 db4e9a22afb51f2b9a127265701dd2ff 242 Pfam PF04055 Radical SAM superfamily 22 175 7.7E-24 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS29350 83cb88eaa814aed316f39c9694f20393 134 ProDom PD082409 MEMBRANE YVAD TRANSMEMBRANE 1 125 5.0E-27 T 28-03-2018 IPR020348 Uncharacterised protein family YvaD SMD44_RS29350 83cb88eaa814aed316f39c9694f20393 134 Pfam PF17314 Family of unknown function (DUF5360) 1 127 2.5E-44 T 28-03-2018 IPR020348 Uncharacterised protein family YvaD SMD44_RS08930 4272ef0a97c9f2c415049936b3f42acc 287 SUPERFAMILY SSF161098 72 265 7.72E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS08930 4272ef0a97c9f2c415049936b3f42acc 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 278 2.9E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS08930 4272ef0a97c9f2c415049936b3f42acc 287 Gene3D G3DSA:1.10.3720.10 33 285 1.1E-48 T 28-03-2018 SMD44_RS08930 4272ef0a97c9f2c415049936b3f42acc 287 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 71 174 5.0E-20 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD44_RS32480 b46473c46f29778bd0e81401fd88be1a 148 Gene3D G3DSA:3.40.50.1010 5 143 6.8E-16 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS32480 b46473c46f29778bd0e81401fd88be1a 148 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 139 12.913 T 28-03-2018 IPR022907 VapC family GO:0004540 SMD44_RS32480 b46473c46f29778bd0e81401fd88be1a 148 SUPERFAMILY SSF88723 7 132 1.99E-13 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS32480 b46473c46f29778bd0e81401fd88be1a 148 Pfam PF01850 PIN domain 7 130 3.0E-14 T 28-03-2018 IPR002716 PIN domain SMD44_RS39090 0cc165d0c856ffe51f5fdc5c8c9531b8 163 SMART SM00257 111 160 2.8E-12 T 28-03-2018 IPR018392 LysM domain SMD44_RS39090 0cc165d0c856ffe51f5fdc5c8c9531b8 163 Pfam PF10648 Immunoglobulin-like domain of bacterial spore germination 5 87 6.1E-14 T 28-03-2018 IPR018911 Bacterial spore germination, immunoglobulin-like domain SMD44_RS39090 0cc165d0c856ffe51f5fdc5c8c9531b8 163 Pfam PF01476 LysM domain 112 160 1.4E-10 T 28-03-2018 IPR018392 LysM domain SMD44_RS39090 0cc165d0c856ffe51f5fdc5c8c9531b8 163 SUPERFAMILY SSF54106 110 160 4.32E-6 T 28-03-2018 IPR018392 LysM domain SMD44_RS39090 0cc165d0c856ffe51f5fdc5c8c9531b8 163 Gene3D G3DSA:3.10.350.10 105 163 4.7E-15 T 28-03-2018 SMD44_RS10010 3216b530dff68ddbf4a4223862419ad2 393 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 112 381 4.5E-76 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 SMD44_RS10010 3216b530dff68ddbf4a4223862419ad2 393 Pfam PF01458 Uncharacterized protein family (UPF0051) 145 364 1.2E-71 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SMD44_RS10010 3216b530dff68ddbf4a4223862419ad2 393 SUPERFAMILY SSF101960 38 390 7.45E-92 T 28-03-2018 SMD44_RS16645 3883e61a5644862616b09e1cefc49158 216 Pfam PF01814 Hemerythrin HHE cation binding domain 11 141 2.4E-18 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 SMD44_RS16645 3883e61a5644862616b09e1cefc49158 216 Gene3D G3DSA:1.20.120.520 3 160 1.1E-22 T 28-03-2018 SMD44_RS43345 0d9964b70b834800c09498aa99c17443 489 Pfam PF12224 Putative amidoligase enzyme 197 350 2.7E-13 T 28-03-2018 IPR022025 Putative amidoligase enzyme SMD44_RS12180 e9ea6925a959e723f87b50c6634c5d7d 423 Pfam PF00999 Sodium/hydrogen exchanger family 16 399 5.1E-37 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD44_RS12180 e9ea6925a959e723f87b50c6634c5d7d 423 Gene3D G3DSA:1.20.91.10 253 335 1.9E-9 T 28-03-2018 SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 1.3E-41 T 28-03-2018 SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 Gene3D G3DSA:3.40.50.720 41 239 2.2E-45 T 28-03-2018 SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 Gene3D G3DSA:3.40.50.720 1 40 1.5E-7 T 28-03-2018 SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 179 0.0013 T 28-03-2018 SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 5.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 5.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 5.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 5.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 5.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05110 09e4a5180a612ad92aa4f08ecd4a64e4 239 SUPERFAMILY SSF51735 3 235 8.54E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS17230 e39282dc3637bcd4deb21da9e8f4c08b 223 Gene3D G3DSA:1.10.1660.10 1 196 1.4E-22 T 28-03-2018 SMD44_RS17230 e39282dc3637bcd4deb21da9e8f4c08b 223 SUPERFAMILY SSF46955 2 70 7.33E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS17230 e39282dc3637bcd4deb21da9e8f4c08b 223 SMART SM00422 3 67 3.9E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS17230 e39282dc3637bcd4deb21da9e8f4c08b 223 Pfam PF13411 MerR HTH family regulatory protein 1 65 1.2E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS30125 36176bfa29e32ab3e08b4485ad414703 201 Pfam PF04264 YceI-like domain 29 195 2.5E-46 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS30125 36176bfa29e32ab3e08b4485ad414703 201 SMART SM00867 28 197 2.7E-75 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS30125 36176bfa29e32ab3e08b4485ad414703 201 Gene3D G3DSA:2.40.128.110 24 201 2.5E-60 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS30125 36176bfa29e32ab3e08b4485ad414703 201 SUPERFAMILY SSF101874 27 199 1.57E-58 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD44_RS24415 d48059c0b98b508086d55378a3f32f84 230 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 15 221 30.752 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMD44_RS24415 d48059c0b98b508086d55378a3f32f84 230 Gene3D G3DSA:3.40.50.1950 16 229 5.9E-44 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS24415 d48059c0b98b508086d55378a3f32f84 230 SUPERFAMILY SSF52507 16 221 1.01E-43 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS24415 d48059c0b98b508086d55378a3f32f84 230 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 96 219 1.8E-35 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMD44_RS24415 d48059c0b98b508086d55378a3f32f84 230 Pfam PF02441 Flavoprotein 17 200 1.3E-16 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD44_RS15840 d11dc0f636c221025a1c9598c7149313 89 Pfam PF04149 Domain of unknown function (DUF397) 35 87 2.7E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS15840 d11dc0f636c221025a1c9598c7149313 89 Pfam PF04149 Domain of unknown function (DUF397) 14 33 4.8E-6 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS32715 83657df63609a0f86d262560b08343ed 242 SUPERFAMILY SSF53098 4 203 1.22E-44 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS32715 83657df63609a0f86d262560b08343ed 242 Gene3D G3DSA:3.30.420.10 6 200 3.7E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS32715 83657df63609a0f86d262560b08343ed 242 Pfam PF00929 Exonuclease 10 178 2.5E-14 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS32715 83657df63609a0f86d262560b08343ed 242 SMART SM00479 7 188 6.1E-11 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS30335 e58dd3e503ae0ecb16ce65205f96f82c 197 SUPERFAMILY SSF53335 2 182 1.41E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS30335 e58dd3e503ae0ecb16ce65205f96f82c 197 Pfam PF03602 Conserved hypothetical protein 95 2 183 1.9E-53 T 28-03-2018 SMD44_RS30335 e58dd3e503ae0ecb16ce65205f96f82c 197 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD44_RS30335 e58dd3e503ae0ecb16ce65205f96f82c 197 PIRSF PIRSF004553 1 186 5.5E-51 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 SMD44_RS30335 e58dd3e503ae0ecb16ce65205f96f82c 197 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 183 1.0E-46 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 SMD44_RS30335 e58dd3e503ae0ecb16ce65205f96f82c 197 Gene3D G3DSA:3.40.50.150 1 190 1.2E-32 T 28-03-2018 SMD44_RS09350 5c8c049213b51c634f167004356e0b78 466 SUPERFAMILY SSF103473 56 447 1.31E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS09350 5c8c049213b51c634f167004356e0b78 466 TIGRFAM TIGR00896 CynX: cyanate transporter 67 427 1.1E-136 T 28-03-2018 IPR004747 Cyanate transport system protein GO:0016021 SMD44_RS09350 5c8c049213b51c634f167004356e0b78 466 Gene3D G3DSA:1.20.1250.20 55 252 7.0E-21 T 28-03-2018 SMD44_RS09350 5c8c049213b51c634f167004356e0b78 466 Pfam PF07690 Major Facilitator Superfamily 84 381 9.5E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS09350 5c8c049213b51c634f167004356e0b78 466 Gene3D G3DSA:1.20.1250.20 260 450 7.8E-17 T 28-03-2018 SMD44_RS14750 904169d93df0ff6e4eafe79eb1bb9d89 81 Pfam PF00403 Heavy-metal-associated domain 16 76 7.0E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD44_RS14750 904169d93df0ff6e4eafe79eb1bb9d89 81 Gene3D G3DSA:3.30.70.100 1 80 1.2E-18 T 28-03-2018 SMD44_RS14750 904169d93df0ff6e4eafe79eb1bb9d89 81 PRINTS PR00944 Copper ion binding protein signature 26 39 1.6E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMD44_RS14750 904169d93df0ff6e4eafe79eb1bb9d89 81 PRINTS PR00944 Copper ion binding protein signature 14 26 1.6E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMD44_RS14750 904169d93df0ff6e4eafe79eb1bb9d89 81 PRINTS PR00944 Copper ion binding protein signature 64 77 1.6E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMD44_RS14750 904169d93df0ff6e4eafe79eb1bb9d89 81 SUPERFAMILY SSF55008 9 78 6.15E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD44_RS12130 60321b3a91ce74bcea9c1041b53091b0 107 Gene3D G3DSA:3.10.450.50 11 104 1.2E-9 T 28-03-2018 SMD44_RS12130 60321b3a91ce74bcea9c1041b53091b0 107 SUPERFAMILY SSF54427 12 102 3.73E-10 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS42820 96fd7b156cc1b23afb2e22462595d9d8 598 SUPERFAMILY SSF48208 192 590 1.36E-97 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS42820 96fd7b156cc1b23afb2e22462595d9d8 598 Gene3D G3DSA:1.50.10.10 189 570 1.3E-92 T 28-03-2018 SMD44_RS42820 96fd7b156cc1b23afb2e22462595d9d8 598 Pfam PF00723 Glycosyl hydrolases family 15 216 582 6.3E-63 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMD44_RS05490 62dfcd369d8c2114127521f15901bc9b 198 Gene3D G3DSA:2.40.260.10 11 198 1.4E-27 T 28-03-2018 IPR023365 Sortase domain SMD44_RS05490 62dfcd369d8c2114127521f15901bc9b 198 SUPERFAMILY SSF63817 53 193 4.45E-17 T 28-03-2018 IPR023365 Sortase domain SMD44_RS05490 62dfcd369d8c2114127521f15901bc9b 198 Pfam PF04203 Sortase family 58 195 5.6E-19 T 28-03-2018 IPR005754 Sortase family SMD44_RS10225 dd5a9b58e068f5a6b02a8efd9d433fa0 366 Pfam PF01699 Sodium/calcium exchanger protein 37 188 7.8E-14 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 SMD44_RS10225 dd5a9b58e068f5a6b02a8efd9d433fa0 366 Pfam PF01699 Sodium/calcium exchanger protein 222 361 4.1E-15 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 SMD44_RS30310 7446fef91a5b463a598f507a520d1e86 417 Gene3D G3DSA:3.50.50.60 15 401 9.6E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS30310 7446fef91a5b463a598f507a520d1e86 417 Pfam PF01494 FAD binding domain 17 349 4.6E-16 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS30310 7446fef91a5b463a598f507a520d1e86 417 SUPERFAMILY SSF51905 280 382 4.63E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS30310 7446fef91a5b463a598f507a520d1e86 417 SUPERFAMILY SSF51905 17 179 4.63E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS30310 7446fef91a5b463a598f507a520d1e86 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 4.3E-10 T 28-03-2018 SMD44_RS30310 7446fef91a5b463a598f507a520d1e86 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 4.3E-10 T 28-03-2018 SMD44_RS30310 7446fef91a5b463a598f507a520d1e86 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 18 40 4.3E-10 T 28-03-2018 SMD44_RS25930 46cec39e241902954d6fd646758f5659 445 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 339 440 1.8E-9 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF SMD44_RS25930 46cec39e241902954d6fd646758f5659 445 Pfam PF04024 PspC domain 35 90 1.8E-15 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal SMD44_RS05305 34928a1ac4523ed01132ced34b357ce8 423 Gene3D G3DSA:3.40.190.10 36 167 2.2E-22 T 28-03-2018 SMD44_RS05305 34928a1ac4523ed01132ced34b357ce8 423 SUPERFAMILY SSF53850 39 411 2.07E-88 T 28-03-2018 SMD44_RS05305 34928a1ac4523ed01132ced34b357ce8 423 Gene3D G3DSA:3.40.190.10 168 350 3.2E-47 T 28-03-2018 SMD44_RS05305 34928a1ac4523ed01132ced34b357ce8 423 Pfam PF13416 Bacterial extracellular solute-binding protein 56 363 2.3E-50 T 28-03-2018 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 Pfam PF00365 Phosphofructokinase 2 297 6.3E-101 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 42.974 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.7E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 SUPERFAMILY SSF53784 1 332 2.75E-120 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 PIRSF PIRSF000532 1 340 2.8E-116 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 Gene3D G3DSA:3.40.50.450 208 332 5.9E-9 T 28-03-2018 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 Gene3D G3DSA:3.40.50.450 1 207 2.6E-76 T 28-03-2018 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD44_RS29235 dca605afff1b04b51e1a7512bfcddd90 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 5.3E-143 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD44_RS14045 96729f9ea7ee821678b738c66fb96023 398 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 352 376 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SMD44_RS14045 96729f9ea7ee821678b738c66fb96023 398 Pfam PF01098 Cell cycle protein 34 393 3.2E-94 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SMD44_RS14045 96729f9ea7ee821678b738c66fb96023 398 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 33 394 4.4E-107 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 SMD44_RS30840 f8d55334d7e9164400c9c867dcbb8f23 149 Gene3D G3DSA:1.20.1260.10 1 123 3.6E-15 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS30840 f8d55334d7e9164400c9c867dcbb8f23 149 SUPERFAMILY SSF47240 2 133 2.43E-38 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS30840 f8d55334d7e9164400c9c867dcbb8f23 149 Pfam PF14530 Domain of unknown function (DUF4439) 3 133 6.4E-47 T 28-03-2018 IPR029447 Domain of unknown function DUF4439 SMD44_RS38465 3c0ee71c0395c2c95956561039af9c70 182 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 18 179 30.132 T 28-03-2018 IPR022939 Uncharacterised protein family UPF0678 SMD44_RS38465 3c0ee71c0395c2c95956561039af9c70 182 Gene3D G3DSA:2.40.128.20 2 179 3.5E-57 T 28-03-2018 IPR012674 Calycin SMD44_RS38465 3c0ee71c0395c2c95956561039af9c70 182 Pfam PF08768 Domain of unknown function (DUF1794) 26 177 1.1E-47 T 28-03-2018 IPR014878 Domain of unknown function DUF1794 SMD44_RS38465 3c0ee71c0395c2c95956561039af9c70 182 SUPERFAMILY SSF50814 23 177 1.17E-42 T 28-03-2018 IPR012674 Calycin SMD44_RS27730 54328af33270e8227ec100602afad851 347 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS27730 54328af33270e8227ec100602afad851 347 SUPERFAMILY SSF52540 20 270 9.06E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27730 54328af33270e8227ec100602afad851 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 315 8.7E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS27730 54328af33270e8227ec100602afad851 347 Pfam PF00005 ABC transporter 41 199 3.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS27730 54328af33270e8227ec100602afad851 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 249 327 4.7E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD44_RS27730 54328af33270e8227ec100602afad851 347 Gene3D G3DSA:3.40.50.300 17 346 1.0E-74 T 28-03-2018 SMD44_RS27730 54328af33270e8227ec100602afad851 347 SMART SM00382 49 249 9.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 SMART SM00320 387 425 6.3E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 SMART SM00320 428 472 0.53 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 SMART SM00320 131 167 6.7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 Gene3D G3DSA:2.130.10.10 380 538 1.9E-20 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 Gene3D G3DSA:2.130.10.120 206 379 3.0E-10 T 28-03-2018 SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 SUPERFAMILY SSF50998 329 476 3.14E-30 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 SUPERFAMILY SSF50998 105 300 3.14E-30 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 Gene3D G3DSA:2.130.10.10 23 205 7.2E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 Pfam PF00400 WD domain, G-beta repeat 450 471 6.2E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS34540 5f9c1ab742c14130f7d6ef05538052f2 587 Pfam PF00400 WD domain, G-beta repeat 389 425 0.0056 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 SMD44_RS17625 bc44ec0c021103cabc8876007ebc50db 256 Gene3D G3DSA:1.10.3630.10 2 201 3.7E-41 T 28-03-2018 SMD44_RS17625 bc44ec0c021103cabc8876007ebc50db 256 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 202 4.3E-47 T 28-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 SUPERFAMILY SSF54909 61 143 1.1E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.4E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.4E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.4E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 SMART SM00344 1 108 1.1E-44 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 Pfam PF01037 Lrp/AsnC ligand binding domain 74 137 4.9E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 1.2E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 Gene3D G3DSA:1.10.10.10 1 52 5.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 Gene3D G3DSA:3.30.70.920 53 146 9.3E-22 T 28-03-2018 SMD44_RS06910 28367e9a94187158011430976e2f2c7a 146 SUPERFAMILY SSF46785 1 60 1.53E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16195 ed4b53ede7202145acdf3444f4379350 132 Pfam PF13581 Histidine kinase-like ATPase domain 3 110 1.2E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16195 ed4b53ede7202145acdf3444f4379350 132 SUPERFAMILY SSF55874 25 113 4.32E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16195 ed4b53ede7202145acdf3444f4379350 132 Gene3D G3DSA:3.30.565.10 1 120 2.0E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 9.1E-51 T 28-03-2018 SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 SUPERFAMILY SSF51735 6 250 4.57E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 Gene3D G3DSA:3.40.50.720 40 252 1.3E-55 T 28-03-2018 SMD44_RS28385 909c0cebfde0993a6583d45622652c9e 252 Gene3D G3DSA:3.40.50.720 1 39 1.7E-10 T 28-03-2018 SMD44_RS43440 277b22a0193545885da4cf3b52191c53 88 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 50 6.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS43440 277b22a0193545885da4cf3b52191c53 88 SUPERFAMILY SSF46785 7 57 5.33E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS43440 277b22a0193545885da4cf3b52191c53 88 Gene3D G3DSA:1.10.10.10 3 67 9.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02315 d670b24fddc40951df10c38ac98be837 320 Pfam PF07859 alpha/beta hydrolase fold 88 294 1.1E-44 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMD44_RS02315 d670b24fddc40951df10c38ac98be837 320 Gene3D G3DSA:3.40.50.1820 9 320 3.8E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02315 d670b24fddc40951df10c38ac98be837 320 SUPERFAMILY SSF53474 32 316 3.82E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS19505 95645e76b80a5a14bede5c5f6984aa38 309 SMART SM00382 29 207 2.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS19505 95645e76b80a5a14bede5c5f6984aa38 309 Gene3D G3DSA:3.40.50.300 1 249 4.9E-55 T 28-03-2018 SMD44_RS19505 95645e76b80a5a14bede5c5f6984aa38 309 Pfam PF00005 ABC transporter 21 159 3.4E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS19505 95645e76b80a5a14bede5c5f6984aa38 309 SUPERFAMILY SSF52540 2 223 1.36E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS17865 9b3972fe78c942daabc49a9bba78445e 373 SUPERFAMILY SSF51679 2 357 1.44E-64 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS17865 9b3972fe78c942daabc49a9bba78445e 373 Pfam PF00296 Luciferase-like monooxygenase 2 328 3.2E-42 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS17865 9b3972fe78c942daabc49a9bba78445e 373 Gene3D G3DSA:3.20.20.30 1 372 4.6E-65 T 28-03-2018 SMD44_RS29630 9802cb5e362bb3bfc7bb1b2f4e135492 339 Gene3D G3DSA:3.90.180.10 1 156 9.3E-39 T 28-03-2018 SMD44_RS29630 9802cb5e362bb3bfc7bb1b2f4e135492 339 SUPERFAMILY SSF51735 131 273 4.31E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29630 9802cb5e362bb3bfc7bb1b2f4e135492 339 Gene3D G3DSA:3.40.50.720 157 310 5.9E-31 T 28-03-2018 SMD44_RS29630 9802cb5e362bb3bfc7bb1b2f4e135492 339 SMART SM00829 23 337 1.8E-42 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD44_RS29630 9802cb5e362bb3bfc7bb1b2f4e135492 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 40 102 1.3E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD44_RS29630 9802cb5e362bb3bfc7bb1b2f4e135492 339 Pfam PF00107 Zinc-binding dehydrogenase 170 265 7.1E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD44_RS29630 9802cb5e362bb3bfc7bb1b2f4e135492 339 SUPERFAMILY SSF50129 14 164 8.37E-36 T 28-03-2018 IPR011032 GroES-like SMD44_RS04175 886f6c466264fe9b5bc07aa978f5ff63 129 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 21 118 1.7E-17 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD44_RS04175 886f6c466264fe9b5bc07aa978f5ff63 129 Gene3D G3DSA:3.30.750.24 18 128 1.7E-14 T 28-03-2018 IPR002645 STAS domain SMD44_RS04175 886f6c466264fe9b5bc07aa978f5ff63 129 Pfam PF13466 STAS domain 29 108 4.0E-9 T 28-03-2018 IPR002645 STAS domain SMD44_RS04175 886f6c466264fe9b5bc07aa978f5ff63 129 SUPERFAMILY SSF52091 18 123 6.87E-20 T 28-03-2018 IPR002645 STAS domain SMD44_RS12750 64eea5a8c5c5600a401c5e4f89452ec1 271 SUPERFAMILY SSF56601 6 267 2.9E-58 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS12750 64eea5a8c5c5600a401c5e4f89452ec1 271 Pfam PF00144 Beta-lactamase 13 263 9.5E-39 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS12750 64eea5a8c5c5600a401c5e4f89452ec1 271 Gene3D G3DSA:3.40.710.10 3 271 8.6E-59 T 28-03-2018 SMD44_RS38600 550eb06b1e72a3907c6a293e2a03284f 645 SUPERFAMILY SSF51645 142 588 2.09E-82 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMD44_RS38600 550eb06b1e72a3907c6a293e2a03284f 645 Pfam PF01274 Malate synthase 138 585 9.9E-80 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMD44_RS38600 550eb06b1e72a3907c6a293e2a03284f 645 Gene3D G3DSA:3.20.20.360 151 479 5.1E-51 T 28-03-2018 SMD44_RS38600 550eb06b1e72a3907c6a293e2a03284f 645 Gene3D G3DSA:1.20.1220.12 480 587 3.1E-28 T 28-03-2018 SMD44_RS33370 eceb75bc4f6baa244464a4fbe4c681ff 466 SUPERFAMILY SSF51556 71 386 1.51E-93 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS33370 eceb75bc4f6baa244464a4fbe4c681ff 466 SUPERFAMILY SSF51338 13 84 8.64E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS33370 eceb75bc4f6baa244464a4fbe4c681ff 466 Gene3D G3DSA:3.20.20.140 85 386 6.4E-62 T 28-03-2018 SMD44_RS33370 eceb75bc4f6baa244464a4fbe4c681ff 466 Pfam PF01979 Amidohydrolase family 69 421 9.4E-61 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS33370 eceb75bc4f6baa244464a4fbe4c681ff 466 Gene3D G3DSA:2.30.40.10 2 84 1.9E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS33370 eceb75bc4f6baa244464a4fbe4c681ff 466 SUPERFAMILY SSF51338 345 464 3.24E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS05865 83937a8fbe0007ee671400b0ce1ba4e2 854 Pfam PF02687 FtsX-like permease family 294 389 1.4E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS05865 83937a8fbe0007ee671400b0ce1ba4e2 854 Pfam PF02687 FtsX-like permease family 756 846 1.6E-13 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS05865 83937a8fbe0007ee671400b0ce1ba4e2 854 Pfam PF12704 MacB-like periplasmic core domain 17 232 8.0E-12 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS05865 83937a8fbe0007ee671400b0ce1ba4e2 854 Pfam PF12704 MacB-like periplasmic core domain 492 697 2.8E-8 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS07715 67e05ecc2cbeb25ecdb0e2ca15a129a8 185 Gene3D G3DSA:1.10.1740.10 16 85 4.2E-9 T 28-03-2018 SMD44_RS07715 67e05ecc2cbeb25ecdb0e2ca15a129a8 185 SUPERFAMILY SSF88659 97 173 1.55E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS07715 67e05ecc2cbeb25ecdb0e2ca15a129a8 185 SUPERFAMILY SSF88946 21 94 1.49E-5 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS07715 67e05ecc2cbeb25ecdb0e2ca15a129a8 185 Gene3D G3DSA:1.10.10.10 86 175 6.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS42205 ecc3d30d64bc562458d7808bef1e0a44 171 SUPERFAMILY SSF50370 41 164 7.55E-9 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS42205 ecc3d30d64bc562458d7808bef1e0a44 171 Gene3D G3DSA:2.80.10.50 39 171 1.4E-7 T 28-03-2018 SMD44_RS15195 1091d21dd9ae8725b9a3eeccfc300dcd 299 Gene3D G3DSA:3.40.190.10 157 236 5.6E-14 T 28-03-2018 SMD44_RS15195 1091d21dd9ae8725b9a3eeccfc300dcd 299 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 27 298 1.7E-75 T 28-03-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 SMD44_RS15195 1091d21dd9ae8725b9a3eeccfc300dcd 299 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 57 282 2.2E-41 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS15195 1091d21dd9ae8725b9a3eeccfc300dcd 299 SUPERFAMILY SSF53850 52 283 2.51E-44 T 28-03-2018 SMD44_RS15195 1091d21dd9ae8725b9a3eeccfc300dcd 299 Gene3D G3DSA:3.40.190.10 46 156 3.4E-23 T 28-03-2018 SMD44_RS15195 1091d21dd9ae8725b9a3eeccfc300dcd 299 SMART SM00062 56 286 1.6E-34 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 Hamap MF_00942 Endonuclease III [nth]. 38 257 37.378 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 SUPERFAMILY SSF48150 54 261 4.71E-69 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 Gene3D G3DSA:1.10.340.30 63 166 1.9E-25 T 28-03-2018 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 TIGRFAM TIGR01083 nth: endonuclease III 53 242 7.2E-74 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 ProSitePatterns PS01155 Endonuclease III family signature. 150 179 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 SMART SM00478 86 233 2.1E-57 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 235 251 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 SMART SM00525 234 254 1.4E-6 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 Pfam PF00633 Helix-hairpin-helix motif 148 170 4.3E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 235 251 3.9E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 Gene3D G3DSA:1.10.1670.10 167 268 1.5E-30 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMD44_RS23190 9b05c0f3e75ed552b595e9e9e0da15ae 298 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 82 210 4.1E-21 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD44_RS29375 8fa60368dbe349936b1802b0229d8296 310 SUPERFAMILY SSF53335 25 292 2.15E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS29375 8fa60368dbe349936b1802b0229d8296 310 Pfam PF13649 Methyltransferase domain 60 161 1.3E-16 T 28-03-2018 SMD44_RS29375 8fa60368dbe349936b1802b0229d8296 310 Gene3D G3DSA:3.40.50.150 21 298 1.7E-34 T 28-03-2018 SMD44_RS05805 fb936c961160ff51d40826767aff6f19 143 Pfam PF13581 Histidine kinase-like ATPase domain 11 134 3.0E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05805 fb936c961160ff51d40826767aff6f19 143 SUPERFAMILY SSF55874 28 137 1.64E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05805 fb936c961160ff51d40826767aff6f19 143 Gene3D G3DSA:3.30.565.10 2 143 3.7E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS02140 d3e54ba5b246973821884274773a0f03 191 Gene3D G3DSA:1.10.3300.10 5 185 3.1E-39 T 28-03-2018 IPR023286 ABATE domain SMD44_RS02140 d3e54ba5b246973821884274773a0f03 191 Pfam PF11706 CGNR zinc finger 140 181 2.0E-15 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS02140 d3e54ba5b246973821884274773a0f03 191 Pfam PF07336 Putative stress-induced transcription regulator 14 135 1.5E-17 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS02140 d3e54ba5b246973821884274773a0f03 191 SUPERFAMILY SSF160904 7 181 1.44E-39 T 28-03-2018 SMD44_RS06320 c0312f4feca6e94ea511d33fe154c8fc 339 SUPERFAMILY SSF81995 4 64 2.62E-6 T 28-03-2018 SMD44_RS34130 f2b04c8ba1676e7e744ff553e786d3de 473 Pfam PF13424 Tetratricopeptide repeat 340 402 1.2E-9 T 28-03-2018 SMD44_RS34130 f2b04c8ba1676e7e744ff553e786d3de 473 Pfam PF13424 Tetratricopeptide repeat 254 312 4.6E-9 T 28-03-2018 SMD44_RS34130 f2b04c8ba1676e7e744ff553e786d3de 473 Pfam PF13374 Tetratricopeptide repeat 416 457 1.9E-4 T 28-03-2018 SMD44_RS34130 f2b04c8ba1676e7e744ff553e786d3de 473 SUPERFAMILY SSF48452 253 314 3.45E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34130 f2b04c8ba1676e7e744ff553e786d3de 473 Gene3D G3DSA:1.10.10.10 350 398 7.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34130 f2b04c8ba1676e7e744ff553e786d3de 473 Gene3D G3DSA:1.10.10.10 399 467 7.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34130 f2b04c8ba1676e7e744ff553e786d3de 473 Gene3D G3DSA:1.10.10.10 260 349 3.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34130 f2b04c8ba1676e7e744ff553e786d3de 473 SUPERFAMILY SSF48452 328 464 2.32E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS27685 f646a3bfa2d84d3c4a970628b7591d8b 540 Gene3D G3DSA:3.10.105.10 304 510 3.5E-37 T 28-03-2018 SMD44_RS27685 f646a3bfa2d84d3c4a970628b7591d8b 540 Gene3D G3DSA:3.90.76.10 49 208 9.2E-31 T 28-03-2018 SMD44_RS27685 f646a3bfa2d84d3c4a970628b7591d8b 540 Gene3D G3DSA:3.40.190.10 209 303 1.3E-14 T 28-03-2018 SMD44_RS27685 f646a3bfa2d84d3c4a970628b7591d8b 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 458 2.8E-51 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain SMD44_RS27685 f646a3bfa2d84d3c4a970628b7591d8b 540 PIRSF PIRSF002741 3 538 2.1E-61 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD44_RS27685 f646a3bfa2d84d3c4a970628b7591d8b 540 SUPERFAMILY SSF53850 38 535 7.96E-91 T 28-03-2018 SMD44_RS05245 41c8297bfbd888c34893d914cc61c44d 147 Gene3D G3DSA:3.90.190.10 20 143 1.5E-11 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMD44_RS05245 41c8297bfbd888c34893d914cc61c44d 147 SUPERFAMILY SSF52799 53 141 3.96E-17 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMD44_RS08785 724255d0e1137ccecdfcfe3fc1aa5b19 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 333 2.2E-29 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 SMD44_RS08785 724255d0e1137ccecdfcfe3fc1aa5b19 333 Gene3D G3DSA:3.40.190.10 141 307 7.2E-13 T 28-03-2018 SMD44_RS08785 724255d0e1137ccecdfcfe3fc1aa5b19 333 SUPERFAMILY SSF53850 44 298 3.62E-8 T 28-03-2018 SMD44_RS08785 724255d0e1137ccecdfcfe3fc1aa5b19 333 PIRSF PIRSF017082 8 333 8.3E-92 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 116 743 5.6E-297 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 SUPERFAMILY SSF51445 187 635 6.24E-109 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 132 214 4.3E-19 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 Pfam PF00128 Alpha amylase, catalytic domain 274 346 1.5E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 PIRSF PIRSF000463 17 745 1.1E-295 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 Gene3D G3DSA:3.20.20.80 244 653 7.6E-75 T 28-03-2018 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 SUPERFAMILY SSF51011 641 744 5.52E-29 T 28-03-2018 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 Gene3D G3DSA:2.60.40.10 13 111 7.8E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 Gene3D G3DSA:2.60.40.10 112 230 1.4E-30 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 108 745 43.46 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 646 744 1.3E-19 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 SMART SM00642 257 622 2.5E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 SUPERFAMILY SSF81296 25 120 4.55E-18 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS29430 6d6e9a5928f64cb072d879469768ac15 745 Gene3D G3DSA:2.60.40.1180 654 745 3.4E-31 T 28-03-2018 SMD44_RS25010 d9631b8a6bf83c66cc5fe1075cf85eb4 311 Pfam PF00877 NlpC/P60 family 209 301 2.7E-21 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS25010 d9631b8a6bf83c66cc5fe1075cf85eb4 311 SUPERFAMILY SSF54001 192 304 7.36E-36 T 28-03-2018 SMD44_RS25010 d9631b8a6bf83c66cc5fe1075cf85eb4 311 Gene3D G3DSA:3.90.1720.10 185 308 4.0E-32 T 28-03-2018 SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 190 3.5E-4 T 28-03-2018 SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 Gene3D G3DSA:3.40.50.720 48 248 1.5E-63 T 28-03-2018 SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 Gene3D G3DSA:3.40.50.720 1 47 2.3E-9 T 28-03-2018 SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 1.0E-59 T 28-03-2018 SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 SUPERFAMILY SSF51735 7 248 5.13E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31870 b1fc5b0264b1a7652ff2eab0e6e7c6a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS23835 2c2156b2062fc63cd64d66ced088e724 335 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 70 157 5.5E-24 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 SMD44_RS23835 2c2156b2062fc63cd64d66ced088e724 335 PIRSF PIRSF006250 48 327 6.8E-94 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 SMD44_RS23835 2c2156b2062fc63cd64d66ced088e724 335 SUPERFAMILY SSF51690 159 324 4.71E-58 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMD44_RS23835 2c2156b2062fc63cd64d66ced088e724 335 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 58 323 2.3E-91 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 SMD44_RS23835 2c2156b2062fc63cd64d66ced088e724 335 Gene3D G3DSA:3.90.1170.20 36 184 1.5E-40 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 SMD44_RS23835 2c2156b2062fc63cd64d66ced088e724 335 SUPERFAMILY SSF54675 48 158 5.49E-27 T 28-03-2018 SMD44_RS23835 2c2156b2062fc63cd64d66ced088e724 335 Gene3D G3DSA:3.20.20.70 185 314 3.1E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS23835 2c2156b2062fc63cd64d66ced088e724 335 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 159 323 8.9E-57 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 SMART SM00342 62 145 5.4E-35 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 SUPERFAMILY SSF46689 98 148 3.81E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 SUPERFAMILY SSF46689 46 96 7.77E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 99 141 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 Pfam PF12833 Helix-turn-helix domain 68 147 2.7E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 Gene3D G3DSA:1.10.10.60 102 153 5.1E-15 T 28-03-2018 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 114 129 4.2E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 129 145 4.2E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD44_RS37695 05324ed0e72203cb8d080dfdf683f0d5 154 Gene3D G3DSA:1.10.10.60 20 101 1.3E-14 T 28-03-2018 SMD44_RS22910 9f605ccc6a0d4dba4f25165d5a84181e 167 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS22910 9f605ccc6a0d4dba4f25165d5a84181e 167 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 91 106 1.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS22910 9f605ccc6a0d4dba4f25165d5a84181e 167 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 106 121 1.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS22910 9f605ccc6a0d4dba4f25165d5a84181e 167 Gene3D G3DSA:1.10.10.10 50 158 9.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22910 9f605ccc6a0d4dba4f25165d5a84181e 167 SUPERFAMILY SSF46785 53 148 9.67E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22910 9f605ccc6a0d4dba4f25165d5a84181e 167 Pfam PF12840 Helix-turn-helix domain 57 115 2.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22910 9f605ccc6a0d4dba4f25165d5a84181e 167 SMART SM00418 56 138 1.1E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS16655 7283ac40ed77d7cd8a5e7c4fede89dc5 455 Pfam PF13520 Amino acid permease 29 414 3.9E-45 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS16655 7283ac40ed77d7cd8a5e7c4fede89dc5 455 PIRSF PIRSF006060 5 454 6.3E-82 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS21470 7ffd3f22d779a8acfac3adf1be6f3521 168 SMART SM00240 94 145 7.6E-13 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS21470 7ffd3f22d779a8acfac3adf1be6f3521 168 SUPERFAMILY SSF49879 66 167 1.21E-27 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS21470 7ffd3f22d779a8acfac3adf1be6f3521 168 Pfam PF00498 FHA domain 96 160 1.5E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS21470 7ffd3f22d779a8acfac3adf1be6f3521 168 Gene3D G3DSA:2.60.200.20 47 168 1.6E-27 T 28-03-2018 SMD44_RS04925 f46a6b89210d57d5fdeab7f8b6e8f7c9 184 Gene3D G3DSA:3.40.630.30 8 98 6.4E-14 T 28-03-2018 SMD44_RS04925 f46a6b89210d57d5fdeab7f8b6e8f7c9 184 Pfam PF13673 Acetyltransferase (GNAT) domain 56 156 1.3E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS04925 f46a6b89210d57d5fdeab7f8b6e8f7c9 184 Gene3D G3DSA:3.40.630.30 99 166 2.5E-13 T 28-03-2018 SMD44_RS04925 f46a6b89210d57d5fdeab7f8b6e8f7c9 184 SUPERFAMILY SSF55729 13 164 3.04E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 Pfam PF12833 Helix-turn-helix domain 245 323 7.8E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 SMART SM00342 239 322 2.2E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 Gene3D G3DSA:3.40.50.880 2 241 2.9E-60 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 SUPERFAMILY SSF52317 17 205 1.83E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 Pfam PF01965 DJ-1/PfpI family 95 184 1.0E-13 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 Gene3D G3DSA:1.10.10.60 279 328 9.1E-10 T 28-03-2018 SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 SUPERFAMILY SSF46689 276 325 3.23E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 Gene3D G3DSA:1.10.10.60 242 278 7.3E-13 T 28-03-2018 SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 276 318 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS05215 3018231ea55bad0cdf4410f9618d06ce 351 SUPERFAMILY SSF46689 225 273 1.02E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29240 fc995adaba1fbbb0196c049e77ee0240 217 Gene3D G3DSA:1.10.260.40 58 135 1.5E-6 T 28-03-2018 SMD44_RS29240 fc995adaba1fbbb0196c049e77ee0240 217 Gene3D G3DSA:1.10.260.40 11 57 1.1E-6 T 28-03-2018 SMD44_RS29240 fc995adaba1fbbb0196c049e77ee0240 217 SUPERFAMILY SSF47413 58 120 8.44E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS29240 fc995adaba1fbbb0196c049e77ee0240 217 SMART SM00530 59 115 0.028 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS29240 fc995adaba1fbbb0196c049e77ee0240 217 SMART SM00530 5 53 11.0 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS02835 0bbfb53e6090d4a18de9e7bd287dbceb 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 327 1.7E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02835 0bbfb53e6090d4a18de9e7bd287dbceb 328 SUPERFAMILY SSF161098 103 315 1.11E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02835 0bbfb53e6090d4a18de9e7bd287dbceb 328 Gene3D G3DSA:1.10.3720.10 2 316 2.1E-32 T 28-03-2018 SMD44_RS35810 112f42917c528cb214ab2a42201462a0 451 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 18 398 1.4E-32 T 28-03-2018 IPR021145 Portal protein SMD44_RS30425 0104200b04253901a0cc90655b1ceaab 492 SUPERFAMILY SSF48452 413 450 1.22E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS30425 0104200b04253901a0cc90655b1ceaab 492 SUPERFAMILY SSF48452 236 353 1.22E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS30425 0104200b04253901a0cc90655b1ceaab 492 Gene3D G3DSA:1.25.40.10 207 491 4.3E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS22850 08ce1558e5f916fc988efe963803189f 218 Pfam PF08281 Sigma-70, region 4 157 210 2.4E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22850 08ce1558e5f916fc988efe963803189f 218 Pfam PF04542 Sigma-70 region 2 66 130 3.2E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22850 08ce1558e5f916fc988efe963803189f 218 SUPERFAMILY SSF88946 60 131 1.22E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22850 08ce1558e5f916fc988efe963803189f 218 Gene3D G3DSA:1.10.1740.10 54 131 3.7E-14 T 28-03-2018 SMD44_RS22850 08ce1558e5f916fc988efe963803189f 218 Gene3D G3DSA:1.10.10.10 138 218 5.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22850 08ce1558e5f916fc988efe963803189f 218 SUPERFAMILY SSF88659 141 215 1.21E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS22850 08ce1558e5f916fc988efe963803189f 218 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 57 216 1.1E-56 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD44_RS22850 08ce1558e5f916fc988efe963803189f 218 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 62 213 8.5E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS16040 e57fb4f1cb1c7d0afc401894f455904a 173 SUPERFAMILY SSF74982 18 146 3.4E-53 T 28-03-2018 IPR023620 Small protein B SMD44_RS16040 e57fb4f1cb1c7d0afc401894f455904a 173 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 23 146 2.0E-58 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 SMD44_RS16040 e57fb4f1cb1c7d0afc401894f455904a 173 Pfam PF01668 SmpB protein 23 163 2.2E-61 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 SMD44_RS16040 e57fb4f1cb1c7d0afc401894f455904a 173 Hamap MF_00023 SsrA-binding protein [smpB]. 1 170 67.415 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 SMD44_RS16040 e57fb4f1cb1c7d0afc401894f455904a 173 ProSitePatterns PS01317 SsrA-binding protein. 41 53 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site SMD44_RS16040 e57fb4f1cb1c7d0afc401894f455904a 173 TIGRFAM TIGR00086 smpB: SsrA-binding protein 23 163 2.3E-58 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 SMD44_RS16040 e57fb4f1cb1c7d0afc401894f455904a 173 Gene3D G3DSA:2.40.280.10 23 141 2.3E-50 T 28-03-2018 IPR023620 Small protein B SMD44_RS07480 804f4e48216606eba5a321922273292f 181 Gene3D G3DSA:1.20.1440.20 14 176 3.5E-36 T 28-03-2018 SMD44_RS11295 e29e49ca0ef4e2b005e704dd5325b032 404 Pfam PF09594 Glycosyltransferase family 87 49 295 3.7E-13 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD44_RS11295 e29e49ca0ef4e2b005e704dd5325b032 404 PIRSF PIRSF010361 1 397 3.8E-75 T 28-03-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane SMD44_RS36985 0a2c431ae9c24840867042931959ac93 118 SUPERFAMILY SSF55729 25 95 1.83E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS36985 0a2c431ae9c24840867042931959ac93 118 Pfam PF14542 GCN5-related N-acetyl-transferase 23 94 5.6E-17 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase SMD44_RS36985 0a2c431ae9c24840867042931959ac93 118 Gene3D G3DSA:3.40.630.30 4 98 9.7E-14 T 28-03-2018 SMD44_RS09590 1b1176f26ad4f149780e91a86ed4b052 286 SMART SM00530 17 72 1.6E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS09590 1b1176f26ad4f149780e91a86ed4b052 286 SUPERFAMILY SSF47413 12 71 1.13E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS09590 1b1176f26ad4f149780e91a86ed4b052 286 Pfam PF13560 Helix-turn-helix domain 17 71 9.5E-13 T 28-03-2018 SMD44_RS09590 1b1176f26ad4f149780e91a86ed4b052 286 Gene3D G3DSA:1.10.260.40 7 86 9.5E-13 T 28-03-2018 SMD44_RS28030 439f857944f3dbe5bd34cd53819c51b6 253 Pfam PF12138 Spherulation-specific family 4 22 246 1.5E-19 T 28-03-2018 IPR021986 Spherulation-specific family 4 SMD44_RS39375 42efb6050b7f9b331ad90ff6cc92a3de 140 Gene3D G3DSA:1.10.10.10 49 118 1.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39375 42efb6050b7f9b331ad90ff6cc92a3de 140 Pfam PF05331 Protein of unknown function (DUF742) 20 140 3.5E-37 T 28-03-2018 IPR007995 Protein of unknown function DUF742 SMD44_RS38310 49340fa1c927ed9f8d52eeb2eff81c5e 252 Pfam PF02585 GlcNAc-PI de-N-acetylase 25 153 2.4E-27 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD44_RS38310 49340fa1c927ed9f8d52eeb2eff81c5e 252 Gene3D G3DSA:3.40.50.10320 1 252 3.6E-55 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS38310 49340fa1c927ed9f8d52eeb2eff81c5e 252 SUPERFAMILY SSF102588 21 219 2.62E-44 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS05840 addb4016f2f83956f393a44f65e0fba4 226 Pfam PF08241 Methyltransferase domain 50 142 6.6E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS05840 addb4016f2f83956f393a44f65e0fba4 226 Gene3D G3DSA:3.40.50.150 8 210 1.7E-20 T 28-03-2018 SMD44_RS05840 addb4016f2f83956f393a44f65e0fba4 226 SUPERFAMILY SSF53335 39 218 2.66E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS33600 baf3818f876f9b5bf6febfa489db2e75 339 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 122 2.6E-17 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS33600 baf3818f876f9b5bf6febfa489db2e75 339 SUPERFAMILY SSF51735 2 152 1.43E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS33600 baf3818f876f9b5bf6febfa489db2e75 339 Gene3D G3DSA:3.30.360.10 135 334 2.6E-45 T 28-03-2018 SMD44_RS33600 baf3818f876f9b5bf6febfa489db2e75 339 Gene3D G3DSA:3.40.50.720 1 134 9.0E-31 T 28-03-2018 SMD44_RS33600 baf3818f876f9b5bf6febfa489db2e75 339 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 240 3.3E-7 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS33600 baf3818f876f9b5bf6febfa489db2e75 339 SUPERFAMILY SSF55347 131 288 2.62E-26 T 28-03-2018 SMD44_RS34985 7b0de71732dc2e2bc957941028b5a949 547 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 126 299 1.5E-56 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 SMD44_RS34985 7b0de71732dc2e2bc957941028b5a949 547 SUPERFAMILY SSF81342 25 302 3.3E-62 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SMD44_RS34985 7b0de71732dc2e2bc957941028b5a949 547 Gene3D G3DSA:1.20.810.10 28 447 1.9E-101 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 SMD44_RS17105 ecf741970172c357ca4ebad7ffda1cff 571 Gene3D G3DSA:3.10.450.100 56 165 1.1E-5 T 28-03-2018 SMD44_RS17105 ecf741970172c357ca4ebad7ffda1cff 571 Pfam PF00905 Penicillin binding protein transpeptidase domain 294 567 2.5E-36 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS17105 ecf741970172c357ca4ebad7ffda1cff 571 Gene3D G3DSA:3.40.710.10 268 568 7.1E-54 T 28-03-2018 SMD44_RS17105 ecf741970172c357ca4ebad7ffda1cff 571 SUPERFAMILY SSF56601 268 567 1.88E-51 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS17105 ecf741970172c357ca4ebad7ffda1cff 571 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 62 170 4.0E-7 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 SMD44_RS18625 d0ac64004f00c17c5923286632d275ad 325 Gene3D G3DSA:3.40.50.1980 161 325 8.0E-31 T 28-03-2018 SMD44_RS18625 d0ac64004f00c17c5923286632d275ad 325 SUPERFAMILY SSF53807 46 319 1.73E-58 T 28-03-2018 SMD44_RS18625 d0ac64004f00c17c5923286632d275ad 325 Gene3D G3DSA:3.40.50.1980 42 160 9.0E-29 T 28-03-2018 SMD44_RS18625 d0ac64004f00c17c5923286632d275ad 325 Pfam PF01497 Periplasmic binding protein 63 300 6.4E-29 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS05085 72f41b3a5e37b48d0edff7aeffeeb8c2 125 Gene3D G3DSA:1.10.1660.10 3 117 2.9E-14 T 28-03-2018 SMD44_RS05085 72f41b3a5e37b48d0edff7aeffeeb8c2 125 Pfam PF13411 MerR HTH family regulatory protein 7 74 2.6E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS05085 72f41b3a5e37b48d0edff7aeffeeb8c2 125 SMART SM00422 6 76 3.1E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS05085 72f41b3a5e37b48d0edff7aeffeeb8c2 125 SUPERFAMILY SSF46955 5 80 6.41E-16 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS07160 8bdbac2b34c5a7eb57674b740c504058 144 Gene3D G3DSA:3.10.450.30 52 144 4.1E-34 T 28-03-2018 SMD44_RS07160 8bdbac2b34c5a7eb57674b740c504058 144 Pfam PF00545 ribonuclease 62 140 1.0E-29 T 28-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 SMD44_RS07160 8bdbac2b34c5a7eb57674b740c504058 144 SUPERFAMILY SSF53933 53 142 7.94E-36 T 28-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD44_RS27050 098e81704ea528519bb9fc02aa8a1097 149 Gene3D G3DSA:1.10.10.10 34 148 9.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27050 098e81704ea528519bb9fc02aa8a1097 149 Pfam PF01638 HxlR-like helix-turn-helix 53 137 1.8E-20 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS27050 098e81704ea528519bb9fc02aa8a1097 149 SUPERFAMILY SSF46785 40 141 4.63E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28635 0f2565505fc3cdfd4ed069c44b368a63 279 SMART SM00641 74 183 2.0E-50 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup SMD44_RS28635 0f2565505fc3cdfd4ed069c44b368a63 279 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 78 111 - T 28-03-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 SMD44_RS28635 0f2565505fc3cdfd4ed069c44b368a63 279 SUPERFAMILY SSF51445 74 278 2.95E-66 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS28635 0f2565505fc3cdfd4ed069c44b368a63 279 Gene3D G3DSA:3.20.20.80 61 279 1.6E-63 T 28-03-2018 SMD44_RS28635 0f2565505fc3cdfd4ed069c44b368a63 279 Pfam PF01183 Glycosyl hydrolases family 25 77 261 3.6E-54 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 SMD44_RS10785 a28d5469b14c570c641e40b4930b1932 145 Pfam PF10825 Protein of unknown function (DUF2752) 51 99 8.1E-16 T 28-03-2018 IPR021215 Protein of unknown function DUF2752 SMD44_RS19700 d6af14161b691df923f9c51fced33e2c 103 SMART SM00418 8 85 2.5E-25 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19700 d6af14161b691df923f9c51fced33e2c 103 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 2.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19700 d6af14161b691df923f9c51fced33e2c 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 9.0E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19700 d6af14161b691df923f9c51fced33e2c 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 9.0E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19700 d6af14161b691df923f9c51fced33e2c 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 9.0E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS19700 d6af14161b691df923f9c51fced33e2c 103 SUPERFAMILY SSF46785 7 92 1.72E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19700 d6af14161b691df923f9c51fced33e2c 103 Gene3D G3DSA:1.10.10.10 3 103 3.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19950 2f52594cedfa897e3b9f23d9f9df6760 278 Gene3D G3DSA:3.40.190.10 1 275 3.2E-5 T 28-03-2018 SMD44_RS19950 2f52594cedfa897e3b9f23d9f9df6760 278 Pfam PF03724 META domain 161 271 6.0E-26 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ SMD44_RS19950 2f52594cedfa897e3b9f23d9f9df6760 278 Pfam PF03724 META domain 50 154 1.1E-17 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ SMD44_RS21535 a4bf11d28a798979c1a712e5a3e02abd 458 Gene3D G3DSA:1.20.1250.20 21 209 2.6E-14 T 28-03-2018 SMD44_RS21535 a4bf11d28a798979c1a712e5a3e02abd 458 SUPERFAMILY SSF103473 21 401 2.22E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS21535 a4bf11d28a798979c1a712e5a3e02abd 458 Gene3D G3DSA:1.20.1250.20 212 404 3.2E-9 T 28-03-2018 SMD44_RS21535 a4bf11d28a798979c1a712e5a3e02abd 458 Pfam PF07690 Major Facilitator Superfamily 43 360 3.5E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS28440 f4c4111dbaf672df7c95455e1fdd82f7 196 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 179 1.7E-20 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS28440 f4c4111dbaf672df7c95455e1fdd82f7 196 SUPERFAMILY SSF55846 18 192 9.95E-25 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS28440 f4c4111dbaf672df7c95455e1fdd82f7 196 Gene3D G3DSA:3.40.80.10 18 192 1.8E-30 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS28440 f4c4111dbaf672df7c95455e1fdd82f7 196 SMART SM00644 27 180 1.5E-21 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS38200 1860fb2ea819483d84a6f8a55ae73eec 269 SUPERFAMILY SSF52218 17 245 2.48E-68 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS38200 1860fb2ea819483d84a6f8a55ae73eec 269 Pfam PF02525 Flavodoxin-like fold 17 224 2.3E-56 T 28-03-2018 IPR003680 Flavodoxin-like fold SMD44_RS38200 1860fb2ea819483d84a6f8a55ae73eec 269 Gene3D G3DSA:3.40.50.360 2 267 2.2E-62 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS01635 f474c63c6a84305deefe6b2eb4606a12 398 Gene3D G3DSA:3.40.710.10 50 398 3.3E-81 T 28-03-2018 SMD44_RS01635 f474c63c6a84305deefe6b2eb4606a12 398 SUPERFAMILY SSF56601 56 373 1.88E-77 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS01635 f474c63c6a84305deefe6b2eb4606a12 398 Pfam PF00144 Beta-lactamase 70 390 1.4E-64 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS43195 a3b4d721ce895f5902a6b9ca6b072b79 237 Gene3D G3DSA:3.40.50.150 18 223 4.1E-27 T 28-03-2018 SMD44_RS43195 a3b4d721ce895f5902a6b9ca6b072b79 237 SUPERFAMILY SSF53335 56 227 1.33E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS43195 a3b4d721ce895f5902a6b9ca6b072b79 237 Pfam PF13649 Methyltransferase domain 67 158 3.9E-12 T 28-03-2018 SMD44_RS41920 33e5da050013294ffa52e3f3ba5b4296 567 Pfam PF00664 ABC transporter transmembrane region 55 236 1.3E-22 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS41920 33e5da050013294ffa52e3f3ba5b4296 567 Gene3D G3DSA:3.40.50.300 276 565 1.7E-66 T 28-03-2018 SMD44_RS41920 33e5da050013294ffa52e3f3ba5b4296 567 Gene3D G3DSA:1.20.1560.10 41 272 3.0E-32 T 28-03-2018 SMD44_RS41920 33e5da050013294ffa52e3f3ba5b4296 567 SMART SM00382 350 536 1.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS41920 33e5da050013294ffa52e3f3ba5b4296 567 SUPERFAMILY SSF52540 336 560 9.11E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS41920 33e5da050013294ffa52e3f3ba5b4296 567 SUPERFAMILY SSF90123 54 270 5.62E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS41920 33e5da050013294ffa52e3f3ba5b4296 567 ProSitePatterns PS00211 ABC transporters family signature. 462 476 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS41920 33e5da050013294ffa52e3f3ba5b4296 567 Pfam PF00005 ABC transporter 342 490 5.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS21655 f565eb09f58bab46c294af39326552a9 300 Gene3D G3DSA:1.10.287.110 151 206 3.5E-5 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS21655 f565eb09f58bab46c294af39326552a9 300 SUPERFAMILY SSF46565 164 205 4.71E-7 T 28-03-2018 IPR001623 DnaJ domain SMD44_RS02895 aa747f0ea77ff64dd586c2d1b16c23c8 116 SUPERFAMILY SSF54593 6 115 2.69E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS02895 aa747f0ea77ff64dd586c2d1b16c23c8 116 Gene3D G3DSA:3.10.180.10 1 116 8.6E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS02895 aa747f0ea77ff64dd586c2d1b16c23c8 116 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 108 1.8E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS03915 aafa6e6416d993402047197f363904da 225 Gene3D G3DSA:2.60.120.590 10 223 8.1E-46 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SMD44_RS03915 aafa6e6416d993402047197f363904da 225 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 16 220 4.2E-43 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SMD44_RS03915 aafa6e6416d993402047197f363904da 225 SUPERFAMILY SSF51197 14 221 2.61E-44 T 28-03-2018 SMD44_RS28060 ecf97815adad6a26945ad29563cf23f8 157 Gene3D G3DSA:1.10.10.10 18 130 9.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28060 ecf97815adad6a26945ad29563cf23f8 157 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 23 82 1.2E-17 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS28060 ecf97815adad6a26945ad29563cf23f8 157 SUPERFAMILY SSF46767 21 81 3.53E-14 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD44_RS35210 fd74c87d2f398255cca681a9cfc55997 597 Gene3D G3DSA:3.50.50.60 9 567 8.2E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS35210 fd74c87d2f398255cca681a9cfc55997 597 SUPERFAMILY SSF51905 518 554 3.24E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS35210 fd74c87d2f398255cca681a9cfc55997 597 SUPERFAMILY SSF51905 49 386 3.24E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS35210 fd74c87d2f398255cca681a9cfc55997 597 Pfam PF01593 Flavin containing amine oxidoreductase 56 553 1.8E-17 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS17175 fe2dadfe68401902ccf21f0d65728853 259 Gene3D G3DSA:3.40.50.300 11 245 1.2E-63 T 28-03-2018 SMD44_RS17175 fe2dadfe68401902ccf21f0d65728853 259 Pfam PF00005 ABC transporter 33 176 5.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS17175 fe2dadfe68401902ccf21f0d65728853 259 SUPERFAMILY SSF52540 15 239 1.22E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS17175 fe2dadfe68401902ccf21f0d65728853 259 SMART SM00382 40 229 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS17175 fe2dadfe68401902ccf21f0d65728853 259 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS20585 78e967243306ba372ba264afc87dab32 458 Gene3D G3DSA:1.10.443.10 233 447 1.3E-25 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS20585 78e967243306ba372ba264afc87dab32 458 SUPERFAMILY SSF56349 172 439 2.83E-26 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS20585 78e967243306ba372ba264afc87dab32 458 Pfam PF00589 Phage integrase family 237 429 1.7E-5 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS20585 78e967243306ba372ba264afc87dab32 458 Gene3D G3DSA:1.10.150.130 70 232 7.7E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS05315 d095a60e6cea00e5d0446278f695215e 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 1.5E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS05315 d095a60e6cea00e5d0446278f695215e 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 50 1.5E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS05315 d095a60e6cea00e5d0446278f695215e 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 1.5E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS05315 d095a60e6cea00e5d0446278f695215e 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.5E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS05315 d095a60e6cea00e5d0446278f695215e 135 Pfam PF12840 Helix-turn-helix domain 19 75 4.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05315 d095a60e6cea00e5d0446278f695215e 135 Gene3D G3DSA:1.10.10.10 2 94 2.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05315 d095a60e6cea00e5d0446278f695215e 135 SMART SM00418 18 94 1.2E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS05315 d095a60e6cea00e5d0446278f695215e 135 SUPERFAMILY SSF46785 14 84 1.73E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34140 485ac7732bce393e5ed629e8db7a19cf 365 Gene3D G3DSA:3.40.50.300 52 324 5.0E-24 T 28-03-2018 SMD44_RS34140 485ac7732bce393e5ed629e8db7a19cf 365 SMART SM00382 62 296 4.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS34140 485ac7732bce393e5ed629e8db7a19cf 365 SUPERFAMILY SSF52540 54 115 1.13E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS34140 485ac7732bce393e5ed629e8db7a19cf 365 SUPERFAMILY SSF52540 181 326 1.13E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43745 a6e40b4d8c8b6152a06a68ce8b8a972c 338 Pfam PF00303 Thymidylate synthase 13 233 1.0E-12 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SMD44_RS43745 a6e40b4d8c8b6152a06a68ce8b8a972c 338 Gene3D G3DSA:3.30.572.10 11 275 7.3E-32 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SMD44_RS43745 a6e40b4d8c8b6152a06a68ce8b8a972c 338 SUPERFAMILY SSF55831 5 256 3.01E-38 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SMD44_RS17805 64157c21d98bcec6e7b3bb006b3c939f 505 SUPERFAMILY SSF89550 188 395 2.75E-34 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD44_RS17805 64157c21d98bcec6e7b3bb006b3c939f 505 SMART SM00481 191 255 0.002 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMD44_RS17805 64157c21d98bcec6e7b3bb006b3c939f 505 Gene3D G3DSA:3.20.20.140 180 383 2.0E-23 T 28-03-2018 SMD44_RS03470 83b324074d331fe117892017aad1211f 372 Pfam PF03060 Nitronate monooxygenase 16 355 6.2E-50 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMD44_RS03470 83b324074d331fe117892017aad1211f 372 Gene3D G3DSA:3.20.20.70 14 369 1.1E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS03470 83b324074d331fe117892017aad1211f 372 SUPERFAMILY SSF51412 22 58 1.01E-42 T 28-03-2018 SMD44_RS03470 83b324074d331fe117892017aad1211f 372 SUPERFAMILY SSF51412 98 315 1.01E-42 T 28-03-2018 SMD44_RS38970 3011271e67a3dc126e0510598a89d3ef 126 SUPERFAMILY SSF54593 33 118 5.04E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS38970 3011271e67a3dc126e0510598a89d3ef 126 Gene3D G3DSA:3.10.180.10 7 123 1.3E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS24730 0f936ecdf1bfc71b3d9875357348d487 231 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 229 4.0E-72 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMD44_RS24730 0f936ecdf1bfc71b3d9875357348d487 231 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 34.477 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMD44_RS24730 0f936ecdf1bfc71b3d9875357348d487 231 SUPERFAMILY SSF53335 4 227 7.28E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS24730 0f936ecdf1bfc71b3d9875357348d487 231 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 229 1.5E-62 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMD44_RS24730 0f936ecdf1bfc71b3d9875357348d487 231 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 SMD44_RS24730 0f936ecdf1bfc71b3d9875357348d487 231 Gene3D G3DSA:3.40.50.150 2 229 8.8E-41 T 28-03-2018 SMD44_RS30945 89368a99868329c884cd6efacc1577cb 432 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 225 333 1.1E-30 T 28-03-2018 IPR021368 Type VII secretion system protein EccE SMD44_RS30945 89368a99868329c884cd6efacc1577cb 432 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 42 432 1.3E-84 T 28-03-2018 IPR021368 Type VII secretion system protein EccE SMD44_RS05880 03ca3714ae04b458c0bfec2c78c31536 337 Pfam PF01595 Domain of unknown function DUF21 8 199 2.8E-41 T 28-03-2018 IPR002550 Domain of unknown function DUF21 SMD44_RS05880 03ca3714ae04b458c0bfec2c78c31536 337 Gene3D G3DSA:3.10.580.10 197 336 1.4E-27 T 28-03-2018 SMD44_RS05880 03ca3714ae04b458c0bfec2c78c31536 337 Pfam PF00571 CBS domain 286 333 1.4E-7 T 28-03-2018 IPR000644 CBS domain SMD44_RS05880 03ca3714ae04b458c0bfec2c78c31536 337 Pfam PF00571 CBS domain 222 271 2.1E-4 T 28-03-2018 IPR000644 CBS domain SMD44_RS05880 03ca3714ae04b458c0bfec2c78c31536 337 SUPERFAMILY SSF54631 205 334 1.21E-24 T 28-03-2018 SMD44_RS05880 03ca3714ae04b458c0bfec2c78c31536 337 SMART SM00116 225 273 0.0097 T 28-03-2018 IPR000644 CBS domain SMD44_RS05880 03ca3714ae04b458c0bfec2c78c31536 337 SMART SM00116 285 333 0.31 T 28-03-2018 IPR000644 CBS domain SMD44_RS32050 31dc35bb19a53f03ec5d0199fc7c6986 294 SUPERFAMILY SSF81345 19 264 2.48E-20 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS32050 31dc35bb19a53f03ec5d0199fc7c6986 294 Gene3D G3DSA:1.10.3470.10 10 276 1.3E-21 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS32050 31dc35bb19a53f03ec5d0199fc7c6986 294 Pfam PF00950 ABC 3 transport family 18 266 2.8E-33 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 SMD44_RS06140 2e193d9fda2a72345318d421929d66c4 230 SUPERFAMILY SSF48613 16 226 6.67E-27 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS06140 2e193d9fda2a72345318d421929d66c4 230 Gene3D G3DSA:1.20.910.10 1 228 7.0E-16 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD44_RS08960 0610109adbb0d5f8d191802abc118cd6 391 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 100 218 8.1E-8 T 28-03-2018 SMD44_RS00985 1c533df849cbaca698f9b760ea353477 140 Gene3D G3DSA:3.30.1330.40 15 136 8.5E-27 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS00985 1c533df849cbaca698f9b760ea353477 140 Pfam PF01042 Endoribonuclease L-PSP 17 136 1.5E-20 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS00985 1c533df849cbaca698f9b760ea353477 140 SUPERFAMILY SSF55298 12 137 2.2E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS43100 2a61480df0e096c813d9920cc5ac771d 224 Pfam PF08666 SAF domain 60 119 4.4E-6 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SMD44_RS43100 2a61480df0e096c813d9920cc5ac771d 224 SMART SM00858 59 122 0.0058 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SMD44_RS43100 2a61480df0e096c813d9920cc5ac771d 224 Gene3D G3DSA:3.90.1210.10 55 140 1.1E-8 T 28-03-2018 SMD44_RS22530 c170b4b0c7b966a1bee5a77651da8fb8 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 276 292 3.5E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22530 c170b4b0c7b966a1bee5a77651da8fb8 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 262 276 3.5E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22530 c170b4b0c7b966a1bee5a77651da8fb8 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 292 304 3.5E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22530 c170b4b0c7b966a1bee5a77651da8fb8 326 SUPERFAMILY SSF46894 248 323 1.09E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS22530 c170b4b0c7b966a1bee5a77651da8fb8 326 Gene3D G3DSA:1.10.10.10 252 326 8.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22530 c170b4b0c7b966a1bee5a77651da8fb8 326 SMART SM00421 259 316 9.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS12075 cc163123876e8fc6b3a9753d7169b21a 317 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 45 266 3.8E-21 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD44_RS12075 cc163123876e8fc6b3a9753d7169b21a 317 SUPERFAMILY SSF51695 40 269 1.26E-38 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS12075 cc163123876e8fc6b3a9753d7169b21a 317 Gene3D G3DSA:3.20.20.190 35 278 2.0E-41 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS33930 7cc01cd6c24c0f60b981fc7cf9fb2052 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 267 3.5E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS33930 7cc01cd6c24c0f60b981fc7cf9fb2052 298 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 69 159 8.5E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD44_RS33930 7cc01cd6c24c0f60b981fc7cf9fb2052 298 SUPERFAMILY SSF161098 68 250 3.27E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS33930 7cc01cd6c24c0f60b981fc7cf9fb2052 298 Gene3D G3DSA:1.10.3720.10 63 268 4.5E-39 T 28-03-2018 SMD44_RS38640 3e4f9b64e7cbd5436113bc2e5e2f347e 279 SMART SM00382 43 231 8.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS38640 3e4f9b64e7cbd5436113bc2e5e2f347e 279 Pfam PF00005 ABC transporter 35 182 6.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS38640 3e4f9b64e7cbd5436113bc2e5e2f347e 279 SUPERFAMILY SSF52540 19 243 2.83E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS38640 3e4f9b64e7cbd5436113bc2e5e2f347e 279 Gene3D G3DSA:3.40.50.300 6 257 5.5E-63 T 28-03-2018 SMD44_RS38640 3e4f9b64e7cbd5436113bc2e5e2f347e 279 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS11090 bf1185cb1aa38bb12d60645694b84c4b 804 SUPERFAMILY SSF54001 422 559 1.68E-31 T 28-03-2018 SMD44_RS11090 bf1185cb1aa38bb12d60645694b84c4b 804 Pfam PF01841 Transglutaminase-like superfamily 437 552 9.6E-25 T 28-03-2018 IPR002931 Transglutaminase-like SMD44_RS11090 bf1185cb1aa38bb12d60645694b84c4b 804 Pfam PF13559 Domain of unknown function (DUF4129) 673 744 5.7E-7 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 SMD44_RS11090 bf1185cb1aa38bb12d60645694b84c4b 804 Gene3D G3DSA:3.90.260.10 433 570 1.1E-16 T 28-03-2018 IPR002931 Transglutaminase-like SMD44_RS11090 bf1185cb1aa38bb12d60645694b84c4b 804 SMART SM00460 484 554 6.4E-21 T 28-03-2018 IPR002931 Transglutaminase-like SMD44_RS00690 d9b9a27bd59a73a5be57a33aa1223b19 224 Gene3D G3DSA:1.10.10.60 1 82 7.8E-19 T 28-03-2018 SMD44_RS00690 d9b9a27bd59a73a5be57a33aa1223b19 224 Gene3D G3DSA:1.10.357.10 83 218 5.5E-24 T 28-03-2018 SMD44_RS00690 d9b9a27bd59a73a5be57a33aa1223b19 224 Pfam PF16859 Bacterial transcriptional repressor C-terminal 91 202 1.2E-30 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS00690 d9b9a27bd59a73a5be57a33aa1223b19 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 78 7.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00690 d9b9a27bd59a73a5be57a33aa1223b19 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00690 d9b9a27bd59a73a5be57a33aa1223b19 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS00690 d9b9a27bd59a73a5be57a33aa1223b19 224 SUPERFAMILY SSF46689 25 85 5.2E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00690 d9b9a27bd59a73a5be57a33aa1223b19 224 SUPERFAMILY SSF48498 92 205 1.09E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS11440 67bf4b3eaefe1da39d3645c805be7e07 398 Gene3D G3DSA:3.40.50.10800 148 264 7.6E-26 T 28-03-2018 SMD44_RS11440 67bf4b3eaefe1da39d3645c805be7e07 398 Hamap MF_00569 Quinolinate synthase A [nadA]. 47 397 57.362 T 28-03-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD44_RS11440 67bf4b3eaefe1da39d3645c805be7e07 398 SUPERFAMILY SSF142754 56 397 1.96E-93 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD44_RS11440 67bf4b3eaefe1da39d3645c805be7e07 398 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 58 397 1.2E-97 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD44_RS11440 67bf4b3eaefe1da39d3645c805be7e07 398 Gene3D G3DSA:3.40.50.10800 51 147 2.1E-17 T 28-03-2018 SMD44_RS11440 67bf4b3eaefe1da39d3645c805be7e07 398 Gene3D G3DSA:3.40.50.10800 265 374 1.4E-22 T 28-03-2018 SMD44_RS11440 67bf4b3eaefe1da39d3645c805be7e07 398 Pfam PF02445 Quinolinate synthetase A protein 57 396 5.3E-107 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD44_RS38105 136166cf81ab30c9f1fd4ada27f70f50 142 Gene3D G3DSA:3.10.180.10 3 141 5.2E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS38105 136166cf81ab30c9f1fd4ada27f70f50 142 SUPERFAMILY SSF54593 8 141 4.27E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS01395 882262045c932b3ba29d7a68c1730b85 222 Gene3D G3DSA:1.25.40.70 68 130 1.8E-7 T 28-03-2018 SMD44_RS01395 882262045c932b3ba29d7a68c1730b85 222 Gene3D G3DSA:1.25.40.70 8 67 5.2E-5 T 28-03-2018 SMD44_RS01395 882262045c932b3ba29d7a68c1730b85 222 Gene3D G3DSA:1.25.40.70 133 207 0.01 T 28-03-2018 SMD44_RS01395 882262045c932b3ba29d7a68c1730b85 222 Pfam PF13646 HEAT repeats 52 123 1.9E-7 T 28-03-2018 SMD44_RS01395 882262045c932b3ba29d7a68c1730b85 222 SUPERFAMILY SSF48371 15 190 4.61E-19 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMD44_RS24640 2aa626045cff12f9bf09f5eead908424 104 SUPERFAMILY SSF49498 34 96 6.28E-6 T 28-03-2018 IPR000833 Alpha-amylase inhibitor GO:0015066 SMD44_RS24640 2aa626045cff12f9bf09f5eead908424 104 Gene3D G3DSA:2.60.40.20 34 104 4.1E-22 T 28-03-2018 SMD44_RS03460 7ce2244b46948e74cbd079aa5deaf3d9 806 Gene3D G3DSA:1.10.1400.10 548 717 4.0E-34 T 28-03-2018 SMD44_RS03460 7ce2244b46948e74cbd079aa5deaf3d9 806 Gene3D G3DSA:3.60.20.10 242 328 7.7E-19 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS03460 7ce2244b46948e74cbd079aa5deaf3d9 806 Gene3D G3DSA:3.60.20.10 339 547 5.4E-26 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS03460 7ce2244b46948e74cbd079aa5deaf3d9 806 Gene3D G3DSA:3.60.20.10 718 796 3.8E-11 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS03460 7ce2244b46948e74cbd079aa5deaf3d9 806 Pfam PF01804 Penicillin amidase 46 793 1.8E-127 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 SMD44_RS03460 7ce2244b46948e74cbd079aa5deaf3d9 806 SUPERFAMILY SSF56235 41 205 7.46E-151 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS03460 7ce2244b46948e74cbd079aa5deaf3d9 806 SUPERFAMILY SSF56235 239 796 7.46E-151 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS03460 7ce2244b46948e74cbd079aa5deaf3d9 806 Gene3D G3DSA:1.10.439.10 36 214 1.7E-34 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 SMD44_RS14300 093919bd720be4cd2502ef118e7a27cd 499 SUPERFAMILY SSF53187 60 107 2.52E-64 T 28-03-2018 SMD44_RS14300 093919bd720be4cd2502ef118e7a27cd 499 SUPERFAMILY SSF53187 249 492 2.52E-64 T 28-03-2018 SMD44_RS14300 093919bd720be4cd2502ef118e7a27cd 499 Gene3D G3DSA:3.40.630.10 55 498 1.5E-61 T 28-03-2018 SMD44_RS14300 093919bd720be4cd2502ef118e7a27cd 499 SUPERFAMILY SSF52025 134 247 7.98E-16 T 28-03-2018 SMD44_RS14300 093919bd720be4cd2502ef118e7a27cd 499 Pfam PF04389 Peptidase family M28 265 486 1.5E-43 T 28-03-2018 IPR007484 Peptidase M28 SMD44_RS14300 093919bd720be4cd2502ef118e7a27cd 499 Pfam PF02225 PA domain 150 239 1.6E-17 T 28-03-2018 IPR003137 PA domain SMD44_RS10085 a6378feff6b2f073fc8ce2af7f76a136 266 SUPERFAMILY SSF100950 7 261 1.45E-62 T 28-03-2018 SMD44_RS10085 a6378feff6b2f073fc8ce2af7f76a136 266 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 12 246 8.4E-75 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 SMD44_RS10085 a6378feff6b2f073fc8ce2af7f76a136 266 Gene3D G3DSA:3.40.50.1360 2 257 1.2E-77 T 28-03-2018 SMD44_RS10085 a6378feff6b2f073fc8ce2af7f76a136 266 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 9 256 2.6E-76 T 28-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 SMD44_RS28180 ebd1b48b266035e4d41238bef376a79d 364 Pfam PF13180 PDZ domain 132 191 9.6E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS28180 ebd1b48b266035e4d41238bef376a79d 364 SUPERFAMILY SSF50156 139 254 1.97E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS28180 ebd1b48b266035e4d41238bef376a79d 364 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 254 343 2.3E-8 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 SMD44_RS28180 ebd1b48b266035e4d41238bef376a79d 364 Gene3D G3DSA:3.30.230.10 40 363 3.7E-45 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS28180 ebd1b48b266035e4d41238bef376a79d 364 SUPERFAMILY SSF54211 217 346 4.55E-20 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS28180 ebd1b48b266035e4d41238bef376a79d 364 SMART SM00228 131 197 1.4E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 SMD44_RS15775 e63cfc389839cd2338da7b05119618bd 314 SUPERFAMILY SSF53850 40 312 1.19E-56 T 28-03-2018 SMD44_RS15775 e63cfc389839cd2338da7b05119618bd 314 Gene3D G3DSA:3.40.190.10 190 310 2.8E-20 T 28-03-2018 SMD44_RS15775 e63cfc389839cd2338da7b05119618bd 314 Gene3D G3DSA:3.40.190.10 30 189 1.0E-23 T 28-03-2018 SMD44_RS15775 e63cfc389839cd2338da7b05119618bd 314 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 40 306 4.0E-58 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD44_RS36990 f1c1a4e9e6186258cea5544c18ee1f65 229 Gene3D G3DSA:3.40.50.1860 110 198 0.0025 T 28-03-2018 SMD44_RS36990 f1c1a4e9e6186258cea5544c18ee1f65 229 Gene3D G3DSA:3.40.50.1860 12 109 5.6E-7 T 28-03-2018 SMD44_RS30410 861c32cffabd320079496dd719008fd0 488 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 21 438 2.3E-96 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMD44_RS30410 861c32cffabd320079496dd719008fd0 488 PIRSF PIRSF002744 1 476 2.0E-108 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMD44_RS05300 08a4b315b06037f568b6d09fb326b189 336 Gene3D G3DSA:1.10.3720.10 41 335 2.6E-55 T 28-03-2018 SMD44_RS05300 08a4b315b06037f568b6d09fb326b189 336 SUPERFAMILY SSF161098 95 322 1.44E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS05300 08a4b315b06037f568b6d09fb326b189 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 329 1.9E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 253 264 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 163 177 4.4E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 252 264 4.4E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 93 108 4.4E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 103 108 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 SUPERFAMILY SSF50494 47 303 5.42E-63 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 Pfam PF00089 Trypsin 61 303 1.7E-50 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 Gene3D G3DSA:2.40.10.10 102 308 3.5E-56 T 28-03-2018 SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 SMART SM00020 60 304 4.1E-60 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD44_RS24660 51f75bb444d1fb6cdfbe3c75a7f5ca34 322 Gene3D G3DSA:2.40.10.10 61 101 4.2E-15 T 28-03-2018 SMD44_RS08135 5c32e80583e66bac399a4db7c4e0f9a1 344 SUPERFAMILY SSF47413 12 72 2.46E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS08135 5c32e80583e66bac399a4db7c4e0f9a1 344 Gene3D G3DSA:3.40.50.2300 187 340 9.8E-35 T 28-03-2018 SMD44_RS08135 5c32e80583e66bac399a4db7c4e0f9a1 344 SUPERFAMILY SSF53822 71 322 3.26E-49 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS08135 5c32e80583e66bac399a4db7c4e0f9a1 344 Gene3D G3DSA:3.40.50.2300 66 186 3.5E-26 T 28-03-2018 SMD44_RS08135 5c32e80583e66bac399a4db7c4e0f9a1 344 SMART SM00354 12 84 1.5E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS08135 5c32e80583e66bac399a4db7c4e0f9a1 344 Gene3D G3DSA:1.10.260.40 11 65 2.5E-22 T 28-03-2018 SMD44_RS08135 5c32e80583e66bac399a4db7c4e0f9a1 344 Pfam PF13377 Periplasmic binding protein-like domain 179 336 1.4E-31 T 28-03-2018 SMD44_RS08135 5c32e80583e66bac399a4db7c4e0f9a1 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 16 61 1.1E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS10090 01f6c4d462fc5a0f82cf1d074d213862 122 Pfam PF05423 Mycobacterium membrane protein 31 113 1.2E-5 T 28-03-2018 IPR008693 Transport accessory protein MmpS SMD44_RS10090 01f6c4d462fc5a0f82cf1d074d213862 122 Gene3D G3DSA:2.60.40.10 19 114 9.0E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS16450 ab5cee07f4c83450f52b2a1cd353ad58 334 Gene3D G3DSA:1.10.340.30 116 298 9.9E-20 T 28-03-2018 SMD44_RS16450 ab5cee07f4c83450f52b2a1cd353ad58 334 SUPERFAMILY SSF48150 133 314 1.3E-28 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD44_RS16330 371fd9e623c7c8e675c86743fd456efb 436 Pfam PF01882 Protein of unknown function DUF58 192 277 5.9E-19 T 28-03-2018 IPR002881 Domain of unknown function DUF58 SMD44_RS16330 371fd9e623c7c8e675c86743fd456efb 436 Gene3D G3DSA:2.60.40.10 46 146 0.0013 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS16330 371fd9e623c7c8e675c86743fd456efb 436 Gene3D G3DSA:3.40.50.410 204 417 2.6E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS16330 371fd9e623c7c8e675c86743fd456efb 436 Pfam PF01345 Domain of unknown function DUF11 54 131 2.3E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 240 250 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 447 457 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 SUPERFAMILY SSF52743 375 526 7.2E-71 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 SUPERFAMILY SSF52743 169 348 7.2E-71 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 193 204 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 188 207 3.7E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 236 249 3.7E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 446 462 3.7E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 Pfam PF00082 Subtilase family 189 483 2.4E-43 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS09420 70fcf293457be3e834b5ee38d0ea3cae 527 Gene3D G3DSA:3.40.50.200 148 527 2.4E-72 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD44_RS04680 c142ed3c877bc6b0d9384589e452160d 269 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 26 223 2.8E-32 T 28-03-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 SMD44_RS04680 c142ed3c877bc6b0d9384589e452160d 269 Pfam PF03837 RecT family 38 232 6.0E-43 T 28-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 SMD44_RS15640 a497cb37f491793eee98b42a495c2157 251 SMART SM00849 18 217 3.3E-6 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS15640 a497cb37f491793eee98b42a495c2157 251 Pfam PF12706 Beta-lactamase superfamily domain 30 218 1.5E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS15640 a497cb37f491793eee98b42a495c2157 251 Gene3D G3DSA:3.60.15.10 1 251 2.0E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS15640 a497cb37f491793eee98b42a495c2157 251 SUPERFAMILY SSF56281 1 247 5.37E-53 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS11960 648776820c18379fc3824cab70746b52 222 Gene3D G3DSA:1.10.357.10 92 222 1.5E-22 T 28-03-2018 SMD44_RS11960 648776820c18379fc3824cab70746b52 222 SUPERFAMILY SSF48498 106 220 5.4E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS11960 648776820c18379fc3824cab70746b52 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 59 89 2.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11960 648776820c18379fc3824cab70746b52 222 Gene3D G3DSA:1.10.10.60 28 91 6.4E-12 T 28-03-2018 SMD44_RS11960 648776820c18379fc3824cab70746b52 222 Pfam PF16859 Bacterial transcriptional repressor C-terminal 106 214 1.2E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS11960 648776820c18379fc3824cab70746b52 222 SUPERFAMILY SSF46689 34 97 3.19E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 Gene3D G3DSA:1.20.1250.20 21 212 2.3E-34 T 28-03-2018 SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 Pfam PF07690 Major Facilitator Superfamily 34 424 2.1E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 SUPERFAMILY SSF103473 15 214 5.89E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 SUPERFAMILY SSF103473 263 434 5.89E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 SUPERFAMILY SSF103473 479 506 5.89E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 92 114 3.2E-9 T 28-03-2018 SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 32 56 3.2E-9 T 28-03-2018 SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 154 178 3.2E-9 T 28-03-2018 SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 415 434 3.2E-9 T 28-03-2018 SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 Gene3D G3DSA:1.20.1250.20 274 510 2.4E-26 T 28-03-2018 SMD44_RS39505 e959f1d46dc1bfeb8b3379700e5c2aa9 513 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 99 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 Gene3D G3DSA:3.20.20.100 5 286 2.5E-96 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 137 154 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 PRINTS PR00069 Aldo-keto reductase signature 171 200 1.1E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 PRINTS PR00069 Aldo-keto reductase signature 209 233 1.1E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 PRINTS PR00069 Aldo-keto reductase signature 49 73 1.1E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 PRINTS PR00069 Aldo-keto reductase signature 105 123 1.1E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 PRINTS PR00069 Aldo-keto reductase signature 137 154 1.1E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 SUPERFAMILY SSF51430 19 279 3.01E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 PIRSF PIRSF000097 13 282 4.8E-88 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 242 257 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMD44_RS34545 08288e7199bfd907dd55a1e005e2e61e 286 Pfam PF00248 Aldo/keto reductase family 30 274 1.8E-46 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 Gene3D G3DSA:1.20.1090.10 664 886 1.8E-63 T 28-03-2018 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 Gene3D G3DSA:3.40.605.10 5 243 2.6E-27 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 PIRSF PIRSF000111 7 883 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 SUPERFAMILY SSF53720 342 474 1.1E-78 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 SUPERFAMILY SSF53720 23 313 1.1E-78 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 Pfam PF00171 Aldehyde dehydrogenase family 20 424 4.7E-22 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 Gene3D G3DSA:3.40.50.1970 451 663 2.3E-49 T 28-03-2018 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 SUPERFAMILY SSF56796 469 882 9.29E-118 T 28-03-2018 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 Pfam PF00465 Iron-containing alcohol dehydrogenase 478 866 2.6E-117 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 652 680 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SMD44_RS08860 aeb15685f9d1705786017bb4646b2e31 886 Gene3D G3DSA:3.40.309.10 244 425 8.9E-27 T 28-03-2018 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 SUPERFAMILY SSF48264 8 397 7.2E-92 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 141 156 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 338 347 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 317 332 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 289 316 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 347 358 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 124 140 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 191 213 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 78 89 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 PRINTS PR00359 B-class P450 signature 272 283 7.6E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 Gene3D G3DSA:1.10.630.10 1 398 1.5E-71 T 28-03-2018 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 Pfam PF00067 Cytochrome P450 33 394 2.3E-33 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS07130 ee69a395f52a7861e7a3e9ec47971aa4 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS26585 e7bcc8e3c34092aad6b2ae242a948f5d 126 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 6 111 3.4E-29 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26585 e7bcc8e3c34092aad6b2ae242a948f5d 126 PIRSF PIRSF000178 2 116 5.9E-10 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26585 e7bcc8e3c34092aad6b2ae242a948f5d 126 Gene3D G3DSA:1.20.1300.10 5 118 3.1E-28 T 28-03-2018 SMD44_RS26585 e7bcc8e3c34092aad6b2ae242a948f5d 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 5 108 6.1E-24 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS26585 e7bcc8e3c34092aad6b2ae242a948f5d 126 SUPERFAMILY SSF81343 2 113 1.05E-28 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD44_RS35100 d2f054b0f84f9701b2baeb9d210f5b33 334 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 190 317 1.8E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS35100 d2f054b0f84f9701b2baeb9d210f5b33 334 SUPERFAMILY SSF47203 192 330 1.11E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS35100 d2f054b0f84f9701b2baeb9d210f5b33 334 Gene3D G3DSA:1.10.540.10 1 121 6.4E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS35100 d2f054b0f84f9701b2baeb9d210f5b33 334 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 3.9E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS35100 d2f054b0f84f9701b2baeb9d210f5b33 334 SUPERFAMILY SSF56645 1 142 6.34E-12 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS35100 d2f054b0f84f9701b2baeb9d210f5b33 334 Gene3D G3DSA:1.20.140.10 168 317 3.3E-29 T 28-03-2018 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 SUPERFAMILY SSF55120 211 400 1.37E-43 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 Pfam PF01479 S4 domain 166 208 4.1E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 Gene3D G3DSA:3.30.2350.10 224 402 8.7E-38 T 28-03-2018 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 SUPERFAMILY SSF55174 158 231 1.3E-11 T 28-03-2018 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 SMART SM00363 166 226 5.8E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 Pfam PF00849 RNA pseudouridylate synthase 227 358 3.8E-25 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 Gene3D G3DSA:3.10.290.10 160 223 1.8E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 264 278 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SMD44_RS09090 7bcebde7c830090c087dbcc2d8ea6e3d 402 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 231 389 1.2E-42 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SMD44_RS19580 cd8395b819ca09f5ee6fd77de64e3319 699 SUPERFAMILY SSF52402 266 407 3.68E-7 T 28-03-2018 SMD44_RS19580 cd8395b819ca09f5ee6fd77de64e3319 699 SUPERFAMILY SSF52402 522 583 3.68E-7 T 28-03-2018 SMD44_RS19580 cd8395b819ca09f5ee6fd77de64e3319 699 Gene3D G3DSA:3.60.20.10 73 206 6.5E-5 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS19580 cd8395b819ca09f5ee6fd77de64e3319 699 Pfam PF00733 Asparagine synthase 271 663 8.0E-8 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD44_RS19580 cd8395b819ca09f5ee6fd77de64e3319 699 SUPERFAMILY SSF56235 75 202 6.79E-14 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS19580 cd8395b819ca09f5ee6fd77de64e3319 699 Gene3D G3DSA:3.40.50.620 207 669 8.2E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS18560 95438843a87e88f583221b67f11e4123 1106 Gene3D G3DSA:3.30.565.10 24 299 1.7E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04935 69419015796970e75f804cb5d454f30a 378 SUPERFAMILY SSF52129 16 196 6.91E-8 T 28-03-2018 IPR029030 Caspase-like domain SMD44_RS04935 69419015796970e75f804cb5d454f30a 378 Gene3D G3DSA:3.40.50.1460 13 218 1.2E-23 T 28-03-2018 SMD44_RS04935 69419015796970e75f804cb5d454f30a 378 Pfam PF00656 Caspase domain 16 170 1.8E-7 T 28-03-2018 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 68 125 7.0E-24 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 Pfam PF00361 Proton-conducting membrane transporter 137 421 3.7E-83 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 627 3.1E-241 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 266 288 1.8E-9 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 88 108 1.8E-9 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 422 444 1.8E-9 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 62 86 1.8E-9 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 114 134 1.0E-58 T 28-03-2018 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 161 182 1.0E-58 T 28-03-2018 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 248 274 1.0E-58 T 28-03-2018 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 316 328 1.0E-58 T 28-03-2018 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 423 442 1.0E-58 T 28-03-2018 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 226 247 1.0E-58 T 28-03-2018 SMD44_RS25075 4233cba0cf9457eea5fcf4423ef04577 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 1.0E-58 T 28-03-2018 SMD44_RS28455 1eb19c454bd8a99a6d645417f45e8096 368 Gene3D G3DSA:1.10.600.10 29 368 1.3E-88 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS28455 1eb19c454bd8a99a6d645417f45e8096 368 SUPERFAMILY SSF48576 76 367 2.52E-70 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS28455 1eb19c454bd8a99a6d645417f45e8096 368 Pfam PF00348 Polyprenyl synthetase 82 312 2.2E-54 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMD44_RS28455 1eb19c454bd8a99a6d645417f45e8096 368 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 121 135 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMD44_RS30735 2ecb47adfc8a0a49ce04844281454dff 473 Pfam PF01266 FAD dependent oxidoreductase 43 407 1.4E-50 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD44_RS30735 2ecb47adfc8a0a49ce04844281454dff 473 Gene3D G3DSA:3.40.50.720 39 146 2.5E-4 T 28-03-2018 SMD44_RS30735 2ecb47adfc8a0a49ce04844281454dff 473 Gene3D G3DSA:3.30.9.10 243 369 3.7E-20 T 28-03-2018 SMD44_RS30735 2ecb47adfc8a0a49ce04844281454dff 473 Gene3D G3DSA:3.30.9.10 147 242 2.5E-8 T 28-03-2018 SMD44_RS30735 2ecb47adfc8a0a49ce04844281454dff 473 SUPERFAMILY SSF51905 19 136 1.06E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS30735 2ecb47adfc8a0a49ce04844281454dff 473 SUPERFAMILY SSF51905 193 323 1.06E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS09415 be61480b19ff07f63e586be0ab7b52d4 122 Pfam PF04341 Protein of unknown function, DUF485 29 115 8.5E-32 T 28-03-2018 IPR007436 Protein of unknown function DUF485 SMD44_RS22620 79e2800fbddce76e1d0defe77cca1a53 275 SUPERFAMILY SSF140959 19 274 1.57E-78 T 28-03-2018 SMD44_RS22620 79e2800fbddce76e1d0defe77cca1a53 275 Pfam PF03301 Tryptophan 2,3-dioxygenase 7 202 5.1E-52 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMD44_RS22620 79e2800fbddce76e1d0defe77cca1a53 275 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 13 275 36.557 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMD44_RS05160 1d92a2a356c4119681272102b415af46 384 PRINTS PR00412 Epoxide hydrolase signature 103 121 3.7E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS05160 1d92a2a356c4119681272102b415af46 384 PRINTS PR00412 Epoxide hydrolase signature 191 204 3.7E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS05160 1d92a2a356c4119681272102b415af46 384 PRINTS PR00412 Epoxide hydrolase signature 132 147 3.7E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS05160 1d92a2a356c4119681272102b415af46 384 PRINTS PR00412 Epoxide hydrolase signature 354 376 3.7E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS05160 1d92a2a356c4119681272102b415af46 384 Gene3D G3DSA:3.40.50.1820 1 384 3.2E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05160 1d92a2a356c4119681272102b415af46 384 SUPERFAMILY SSF53474 2 378 2.09E-82 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05160 1d92a2a356c4119681272102b415af46 384 Pfam PF06441 Epoxide hydrolase N terminus 3 112 1.8E-29 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 SMD44_RS05160 1d92a2a356c4119681272102b415af46 384 PIRSF PIRSF001112 1 383 2.0E-95 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 SMD44_RS05510 8424106399243f254895c90d0cc57fa7 417 Pfam PF08281 Sigma-70, region 4 121 165 1.6E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05510 8424106399243f254895c90d0cc57fa7 417 SUPERFAMILY SSF88946 6 73 2.67E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05510 8424106399243f254895c90d0cc57fa7 417 Gene3D G3DSA:1.10.1740.10 3 78 7.1E-16 T 28-03-2018 SMD44_RS05510 8424106399243f254895c90d0cc57fa7 417 Gene3D G3DSA:1.10.10.10 79 218 1.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05510 8424106399243f254895c90d0cc57fa7 417 SUPERFAMILY SSF88659 109 167 2.05E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05510 8424106399243f254895c90d0cc57fa7 417 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 166 4.2E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS05510 8424106399243f254895c90d0cc57fa7 417 Pfam PF04542 Sigma-70 region 2 10 75 2.6E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS27090 80b89fd2867adecf26808a4e139c04b4 372 Gene3D G3DSA:1.25.40.10 70 330 5.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS06245 5a7c57da410db209e09e78e657d05f1b 136 SUPERFAMILY SSF54593 8 128 5.91E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS06245 5a7c57da410db209e09e78e657d05f1b 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 124 2.2E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS06245 5a7c57da410db209e09e78e657d05f1b 136 Gene3D G3DSA:3.10.180.10 6 135 4.1E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS32720 412159ce56cbe8a7e2a1e9580afd510f 288 Pfam PF01636 Phosphotransferase enzyme family 33 235 3.5E-16 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS32720 412159ce56cbe8a7e2a1e9580afd510f 288 Gene3D G3DSA:1.10.510.10 51 237 3.2E-14 T 28-03-2018 SMD44_RS32720 412159ce56cbe8a7e2a1e9580afd510f 288 SUPERFAMILY SSF56112 2 259 1.09E-32 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS32075 eac5ea92016d06181341e06fa10a4dc5 127 Pfam PF04472 Cell division protein SepF 48 117 5.3E-19 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SMD44_RS01065 8d162c7893465d080ae369b947578e2b 577 SUPERFAMILY SSF110921 473 556 9.29E-10 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS01065 8d162c7893465d080ae369b947578e2b 577 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 17 563 4.7E-157 T 28-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 SMD44_RS01065 8d162c7893465d080ae369b947578e2b 577 Pfam PF08502 LeuA allosteric (dimerisation) domain 388 558 4.8E-11 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS01065 8d162c7893465d080ae369b947578e2b 577 SMART SM00917 387 560 7.4E-14 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS01065 8d162c7893465d080ae369b947578e2b 577 Pfam PF00682 HMGL-like 18 269 1.8E-40 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMD44_RS01065 8d162c7893465d080ae369b947578e2b 577 SUPERFAMILY SSF51569 13 306 1.56E-69 T 28-03-2018 SMD44_RS01065 8d162c7893465d080ae369b947578e2b 577 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 24 40 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD44_RS01065 8d162c7893465d080ae369b947578e2b 577 Gene3D G3DSA:3.20.20.70 3 360 4.0E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13730 414d1bd5294bcfffc69fcf031002a9d7 118 SUPERFAMILY SSF142906 1 115 3.66E-41 T 28-03-2018 SMD44_RS13730 414d1bd5294bcfffc69fcf031002a9d7 118 Pfam PF04237 YjbR 11 102 8.6E-29 T 28-03-2018 IPR007351 Uncharacterised protein YjbR SMD44_RS35320 9b4b4d0a24b71a7b4b87af4aeaf730fe 395 SUPERFAMILY SSF51735 10 164 3.58E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35320 9b4b4d0a24b71a7b4b87af4aeaf730fe 395 Gene3D G3DSA:3.40.50.720 1 150 4.2E-22 T 28-03-2018 SMD44_RS35320 9b4b4d0a24b71a7b4b87af4aeaf730fe 395 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 12 120 3.6E-12 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 SMD44_RS28760 6526dc5461a16d092b0fc5b568ff2a4f 273 Pfam PF12147 Putative methyltransferase 4 262 2.0E-72 T 28-03-2018 IPR022744 Methyltransferase domain, putative SMD44_RS28760 6526dc5461a16d092b0fc5b568ff2a4f 273 SUPERFAMILY SSF53335 64 253 1.88E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS28760 6526dc5461a16d092b0fc5b568ff2a4f 273 Gene3D G3DSA:3.40.50.150 60 254 1.2E-24 T 28-03-2018 SMD44_RS32305 d51775b18aaee02e88921afcb47cd2b9 438 Pfam PF02653 Branched-chain amino acid transport system / permease component 89 422 8.6E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS32305 d51775b18aaee02e88921afcb47cd2b9 438 Gene3D G3DSA:1.10.3470.10 79 431 1.2E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS07195 a709d148e2c29aa72b2ee9b2fc93d1bf 216 Gene3D G3DSA:1.10.357.10 2 211 2.1E-33 T 28-03-2018 SMD44_RS07195 a709d148e2c29aa72b2ee9b2fc93d1bf 216 SUPERFAMILY SSF48498 104 211 8.9E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS07195 a709d148e2c29aa72b2ee9b2fc93d1bf 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 81 2.5E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS07195 a709d148e2c29aa72b2ee9b2fc93d1bf 216 SUPERFAMILY SSF46689 26 97 2.08E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS07195 a709d148e2c29aa72b2ee9b2fc93d1bf 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 3.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS07195 a709d148e2c29aa72b2ee9b2fc93d1bf 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 3.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS19090 09092bfc2ddf3812d4d7bfa97f355b73 529 SMART SM00448 77 261 0.0046 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19090 09092bfc2ddf3812d4d7bfa97f355b73 529 SMART SM00331 303 527 5.6E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19090 09092bfc2ddf3812d4d7bfa97f355b73 529 SUPERFAMILY SSF52172 74 134 2.99E-6 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS19090 09092bfc2ddf3812d4d7bfa97f355b73 529 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 332 527 3.6E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19090 09092bfc2ddf3812d4d7bfa97f355b73 529 SUPERFAMILY SSF52172 207 292 3.21E-6 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS19090 09092bfc2ddf3812d4d7bfa97f355b73 529 Gene3D G3DSA:3.60.40.10 281 528 2.5E-24 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS19090 09092bfc2ddf3812d4d7bfa97f355b73 529 Gene3D G3DSA:3.40.50.2300 73 280 4.0E-26 T 28-03-2018 SMD44_RS25320 832edc27fd977e1aa5e525971a737466 88 Pfam PF04226 Transglycosylase associated protein 33 83 2.4E-7 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SMD44_RS22590 b3948dab3138143d466dad38cc2f4458 292 Gene3D G3DSA:3.30.530.20 1 160 3.5E-13 T 28-03-2018 IPR023393 START-like domain SMD44_RS22590 b3948dab3138143d466dad38cc2f4458 292 SUPERFAMILY SSF55961 1 146 3.41E-16 T 28-03-2018 SMD44_RS22590 b3948dab3138143d466dad38cc2f4458 292 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 146 2.4E-7 T 28-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G SMD44_RS12305 ace5f784a13ab16677e2e84a1233c912 331 Gene3D G3DSA:3.40.630.40 101 331 4.9E-39 T 28-03-2018 SMD44_RS12305 ace5f784a13ab16677e2e84a1233c912 331 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 115 326 2.7E-32 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SMD44_RS12305 ace5f784a13ab16677e2e84a1233c912 331 SMART SM00646 198 326 1.0E-14 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SMD44_RS12305 ace5f784a13ab16677e2e84a1233c912 331 SUPERFAMILY SSF53187 112 329 3.45E-29 T 28-03-2018 SMD44_RS41880 1c3f62e8117eee969c237e61d9fa4743 372 Pfam PF00487 Fatty acid desaturase 67 334 8.3E-26 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SMD44_RS19095 236e5b998ed0647404497459a13b9df3 112 Pfam PF10724 Protein of unknown function (DUF2516) 7 92 1.2E-31 T 28-03-2018 IPR019662 Protein of unknown function DUF2516 SMD44_RS16915 d604572126cc156c348ba3b59c07a76e 188 Pfam PF14431 YwqJ-like deaminase 55 177 1.1E-23 T 28-03-2018 IPR025968 YwqJ-like deaminase SMD44_RS22710 26be4e7293f9877e155057793252c79d 198 Pfam PF01965 DJ-1/PfpI family 7 168 2.8E-32 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS22710 26be4e7293f9877e155057793252c79d 198 Gene3D G3DSA:3.40.50.880 1 197 1.4E-29 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS22710 26be4e7293f9877e155057793252c79d 198 SUPERFAMILY SSF52317 7 170 1.09E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS06710 64d8544061ee6b19e005df68de948e68 396 SUPERFAMILY SSF53901 180 369 1.29E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS06710 64d8544061ee6b19e005df68de948e68 396 SUPERFAMILY SSF53901 17 119 1.29E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS06710 64d8544061ee6b19e005df68de948e68 396 Pfam PF00108 Thiolase, N-terminal domain 24 111 1.4E-6 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD44_RS06710 64d8544061ee6b19e005df68de948e68 396 PIRSF PIRSF000429 1 396 2.4E-32 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS06710 64d8544061ee6b19e005df68de948e68 396 Gene3D G3DSA:3.40.47.10 218 394 3.1E-15 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS06710 64d8544061ee6b19e005df68de948e68 396 Gene3D G3DSA:3.40.47.10 18 217 1.7E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS32330 7c67bbff9f743f8d6c752707ca2ddb02 744 SUPERFAMILY SSF158472 679 725 8.24E-6 T 28-03-2018 SMD44_RS32330 7c67bbff9f743f8d6c752707ca2ddb02 744 Pfam PF00672 HAMP domain 680 723 4.0E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS32330 7c67bbff9f743f8d6c752707ca2ddb02 744 SMART SM00304 326 378 0.65 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS32330 7c67bbff9f743f8d6c752707ca2ddb02 744 SMART SM00304 678 730 0.0067 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS32330 7c67bbff9f743f8d6c752707ca2ddb02 744 Gene3D G3DSA:3.30.450.20 439 504 2.3E-6 T 28-03-2018 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 430 1.8E-106 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 Gene3D G3DSA:3.65.10.10 29 239 2.3E-54 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 438 28.876 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 PIRSF PIRSF000505 8 438 6.7E-114 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 Gene3D G3DSA:3.65.10.10 240 436 3.3E-51 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 SUPERFAMILY SSF55205 16 435 3.14E-102 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 ProSitePatterns PS00104 EPSP synthase signature 1. 98 112 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 436 3.0E-113 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD44_RS28245 3dc76b9d67959a3bd30487d5616391b0 438 ProSitePatterns PS00885 EPSP synthase signature 2. 351 369 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD44_RS02675 ada9ac184da6a1ccdb890bf48694f8e6 285 SUPERFAMILY SSF51569 3 283 6.89E-79 T 28-03-2018 SMD44_RS02675 ada9ac184da6a1ccdb890bf48694f8e6 285 Gene3D G3DSA:3.20.20.70 1 285 2.7E-87 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS02675 ada9ac184da6a1ccdb890bf48694f8e6 285 PIRSF PIRSF001359 1 285 2.5E-72 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD44_RS02675 ada9ac184da6a1ccdb890bf48694f8e6 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 283 1.5E-78 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD44_RS02675 ada9ac184da6a1ccdb890bf48694f8e6 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 282 1.1E-71 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD44_RS33330 956959d9258f42e8eae512dd891a3119 296 SUPERFAMILY SSF51735 5 165 1.05E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS33330 956959d9258f42e8eae512dd891a3119 296 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 6 295 5.0E-150 T 28-03-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 SMD44_RS33330 956959d9258f42e8eae512dd891a3119 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 286 4.8E-41 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMD44_RS33330 956959d9258f42e8eae512dd891a3119 296 Gene3D G3DSA:1.10.1040.10 166 296 9.6E-37 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS33330 956959d9258f42e8eae512dd891a3119 296 PIRSF PIRSF000103 1 295 8.0E-84 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS33330 956959d9258f42e8eae512dd891a3119 296 Gene3D G3DSA:3.40.50.720 4 165 6.4E-38 T 28-03-2018 SMD44_RS33330 956959d9258f42e8eae512dd891a3119 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 165 1.8E-50 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS33330 956959d9258f42e8eae512dd891a3119 296 SUPERFAMILY SSF48179 166 294 5.1E-38 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS15215 329b18894320648568e3500c7782792d 252 SUPERFAMILY SSF46785 13 81 1.04E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15215 329b18894320648568e3500c7782792d 252 SUPERFAMILY SSF55781 76 241 1.96E-24 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS15215 329b18894320648568e3500c7782792d 252 Gene3D G3DSA:3.30.450.40 81 251 4.8E-24 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS15215 329b18894320648568e3500c7782792d 252 Pfam PF01614 Bacterial transcriptional regulator 133 229 2.0E-14 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS15215 329b18894320648568e3500c7782792d 252 Gene3D G3DSA:1.10.10.10 8 80 6.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15215 329b18894320648568e3500c7782792d 252 Pfam PF09339 IclR helix-turn-helix domain 14 62 5.1E-6 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS41820 3bc945b568712a2437332aa7ced366e9 331 Gene3D G3DSA:1.10.10.60 63 267 8.3E-9 T 28-03-2018 SMD44_RS41820 3bc945b568712a2437332aa7ced366e9 331 Gene3D G3DSA:1.10.10.60 268 324 3.8E-11 T 28-03-2018 SMD44_RS41820 3bc945b568712a2437332aa7ced366e9 331 Pfam PF14525 AraC-binding-like domain 20 197 4.0E-27 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMD44_RS41820 3bc945b568712a2437332aa7ced366e9 331 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 270 315 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD44_RS41820 3bc945b568712a2437332aa7ced366e9 331 SMART SM00342 232 319 2.7E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS41820 3bc945b568712a2437332aa7ced366e9 331 Pfam PF12833 Helix-turn-helix domain 238 320 7.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS41820 3bc945b568712a2437332aa7ced366e9 331 SUPERFAMILY SSF46689 270 321 6.72E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS23920 ad6277485d8628e574e9431adb826b16 148 SUPERFAMILY SSF54593 1 138 4.16E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS23920 ad6277485d8628e574e9431adb826b16 148 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 132 8.1E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS23920 ad6277485d8628e574e9431adb826b16 148 Gene3D G3DSA:3.10.180.10 1 148 2.8E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS41025 941af26bbc9f81a2ca7eada7bd94c668 334 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 25 311 8.1E-56 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF SMD44_RS41025 941af26bbc9f81a2ca7eada7bd94c668 334 Gene3D G3DSA:1.10.620.20 58 280 1.2E-4 T 28-03-2018 SMD44_RS08675 c2c064585fc3bfefcc2e55c687008bcd 196 Pfam PF08281 Sigma-70, region 4 135 188 1.5E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS08675 c2c064585fc3bfefcc2e55c687008bcd 196 SUPERFAMILY SSF88946 17 117 6.75E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS08675 c2c064585fc3bfefcc2e55c687008bcd 196 SUPERFAMILY SSF88659 128 193 1.09E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS08675 c2c064585fc3bfefcc2e55c687008bcd 196 Gene3D G3DSA:1.10.10.10 114 196 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08675 c2c064585fc3bfefcc2e55c687008bcd 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 192 5.7E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS08675 c2c064585fc3bfefcc2e55c687008bcd 196 Pfam PF04542 Sigma-70 region 2 43 104 5.0E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS08675 c2c064585fc3bfefcc2e55c687008bcd 196 Gene3D G3DSA:1.10.1740.10 13 113 1.1E-20 T 28-03-2018 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 331 433 3.0E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 Gene3D G3DSA:3.30.565.10 273 438 1.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 SMART SM00388 220 288 4.8E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 SUPERFAMILY SSF55874 287 432 1.07E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 SUPERFAMILY SSF47384 203 283 1.96E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 285 7.8E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 Pfam PF00672 HAMP domain 167 216 3.8E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 SUPERFAMILY SSF158472 167 216 3.92E-8 T 28-03-2018 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 SMART SM00387 328 434 2.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 SMART SM00304 166 219 1.0E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 412 5.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 389 5.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 5.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 431 5.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS01170 f75805c98bb2a978a308e2ac35b90af8 444 Gene3D G3DSA:1.10.287.130 210 272 1.3E-14 T 28-03-2018 SMD44_RS12170 705204a29be704e55c50022a9ab21c1d 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 75 2.5E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS12170 705204a29be704e55c50022a9ab21c1d 255 Pfam PF03704 Bacterial transcriptional activator domain 95 239 2.4E-45 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS12170 705204a29be704e55c50022a9ab21c1d 255 SUPERFAMILY SSF48452 90 248 6.32E-38 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12170 705204a29be704e55c50022a9ab21c1d 255 Gene3D G3DSA:1.25.40.10 92 249 9.9E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12170 705204a29be704e55c50022a9ab21c1d 255 SUPERFAMILY SSF46894 2 88 9.07E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS12170 705204a29be704e55c50022a9ab21c1d 255 Gene3D G3DSA:1.10.10.10 1 91 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS12170 705204a29be704e55c50022a9ab21c1d 255 SMART SM00862 15 88 3.5E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS12170 705204a29be704e55c50022a9ab21c1d 255 SMART SM01043 95 239 2.6E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS13280 4b317b39d936d278458660431bafa868 77 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 43 1.1E-16 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 4.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 4.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 4.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 4.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 4.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 4.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 Gene3D G3DSA:3.40.50.720 1 269 9.6E-62 T 28-03-2018 SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 27 263 2.9E-45 T 28-03-2018 SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 4.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 4.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 4.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS09890 06019d0e60ce21940dbb28f9ddea8dc3 269 SUPERFAMILY SSF51735 16 267 3.36E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24035 b1780758329e7ea35f75b876f6f2c4ea 245 PIRSF PIRSF006648 2 245 5.3E-22 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS24035 b1780758329e7ea35f75b876f6f2c4ea 245 Pfam PF01061 ABC-2 type transporter 9 206 1.9E-35 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS02130 15d858b5e80ce679611e117e4efe80d7 150 Pfam PF12802 MarR family 34 87 4.2E-8 T 28-03-2018 SMD44_RS02130 15d858b5e80ce679611e117e4efe80d7 150 SMART SM00347 29 129 1.5E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS02130 15d858b5e80ce679611e117e4efe80d7 150 Gene3D G3DSA:1.10.10.10 1 147 8.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02130 15d858b5e80ce679611e117e4efe80d7 150 SUPERFAMILY SSF46785 6 144 1.99E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15205 b1ec3a1cd7550c58dd46d40d067ef6d1 221 Gene3D G3DSA:1.10.3720.10 1 221 5.2E-40 T 28-03-2018 SMD44_RS15205 b1ec3a1cd7550c58dd46d40d067ef6d1 221 SUPERFAMILY SSF161098 18 205 1.96E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15205 b1ec3a1cd7550c58dd46d40d067ef6d1 221 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 8 219 9.2E-78 T 28-03-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD SMD44_RS15205 b1ec3a1cd7550c58dd46d40d067ef6d1 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 114 6.5E-29 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD44_RS15205 b1ec3a1cd7550c58dd46d40d067ef6d1 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 219 2.6E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS29750 fa8cf6cf5f6c1d51362b2c3b7ffd7932 221 SUPERFAMILY SSF46689 12 84 2.43E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS29750 fa8cf6cf5f6c1d51362b2c3b7ffd7932 221 Gene3D G3DSA:1.10.357.10 4 206 2.6E-31 T 28-03-2018 SMD44_RS29750 fa8cf6cf5f6c1d51362b2c3b7ffd7932 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 6.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS20455 4f5eb90954f25b87adcc0ad81d8b04ef 373 SUPERFAMILY SSF50249 205 335 9.25E-35 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS20455 4f5eb90954f25b87adcc0ad81d8b04ef 373 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 220 256 2.4E-8 T 28-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMD44_RS20455 4f5eb90954f25b87adcc0ad81d8b04ef 373 Pfam PF13452 N-terminal half of MaoC dehydratase 39 163 9.3E-16 T 28-03-2018 SMD44_RS20455 4f5eb90954f25b87adcc0ad81d8b04ef 373 Gene3D G3DSA:3.10.129.10 20 191 2.2E-31 T 28-03-2018 SMD44_RS20455 4f5eb90954f25b87adcc0ad81d8b04ef 373 SUPERFAMILY SSF54637 43 170 5.86E-14 T 28-03-2018 IPR029069 HotDog domain SMD44_RS20455 4f5eb90954f25b87adcc0ad81d8b04ef 373 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 258 329 2.2E-20 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMD44_RS20455 4f5eb90954f25b87adcc0ad81d8b04ef 373 Gene3D G3DSA:2.40.50.140 260 333 4.4E-20 T 28-03-2018 SMD44_RS10735 9800c627cacb9344a87a8315e2e60610 489 Pfam PF03747 ADP-ribosylglycohydrolase 139 445 1.5E-62 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10735 9800c627cacb9344a87a8315e2e60610 489 Gene3D G3DSA:1.10.4080.10 131 481 1.4E-58 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10735 9800c627cacb9344a87a8315e2e60610 489 SUPERFAMILY SSF101478 132 454 1.31E-43 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS19160 cd2eac46f357a4d7a37a74f85ac605a2 379 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 344 2.8E-62 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS19160 cd2eac46f357a4d7a37a74f85ac605a2 379 Gene3D G3DSA:3.40.50.1100 65 176 3.3E-29 T 28-03-2018 SMD44_RS19160 cd2eac46f357a4d7a37a74f85ac605a2 379 Gene3D G3DSA:3.40.50.1100 177 370 3.5E-29 T 28-03-2018 SMD44_RS19160 cd2eac46f357a4d7a37a74f85ac605a2 379 SUPERFAMILY SSF53686 45 346 8.12E-56 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD44_RS10060 5f67236c1436b3499eb27a6ac0b9a9c6 344 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 55 342 19.484 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SMD44_RS10060 5f67236c1436b3499eb27a6ac0b9a9c6 344 Pfam PF01040 UbiA prenyltransferase family 71 326 1.8E-66 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMD44_RS10060 5f67236c1436b3499eb27a6ac0b9a9c6 344 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 110 132 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site SMD44_RS10060 5f67236c1436b3499eb27a6ac0b9a9c6 344 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 57 340 8.2E-97 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 5.1E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 5.1E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 5.1E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 PRINTS PR01466 Bacterial arginine deiminase signature 1 20 5.1E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 5.1E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 5.1E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 SUPERFAMILY SSF55909 2 407 3.34E-124 T 28-03-2018 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 Pfam PF02274 Amidinotransferase 17 404 2.0E-94 T 28-03-2018 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 Gene3D G3DSA:3.75.10.10 2 405 2.6E-100 T 28-03-2018 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 Hamap MF_00242 Arginine deiminase [arcA]. 1 407 41.756 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD44_RS32140 280098c3e20f7fc05ea5849e8efc312d 408 PIRSF PIRSF006356 1 407 8.8E-149 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD44_RS31905 734bfaf487e44d7e3986bacb3045fc2d 255 PIRSF PIRSF010219 15 242 4.9E-80 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 SMD44_RS31905 734bfaf487e44d7e3986bacb3045fc2d 255 Pfam PF11361 Protein of unknown function (DUF3159) 42 228 1.2E-57 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 Gene3D G3DSA:2.140.10.10 392 576 1.8E-13 T 28-03-2018 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 SMART SM00220 16 275 7.2E-41 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 Gene3D G3DSA:2.140.10.10 577 774 3.7E-17 T 28-03-2018 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 53 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 SMART SM00564 458 489 710.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 SMART SM00564 542 583 14.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 SMART SM00564 591 623 11.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 SMART SM00564 503 533 260.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 Gene3D G3DSA:1.10.510.10 107 278 7.1E-42 T 28-03-2018 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 143 155 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 Pfam PF00069 Protein kinase domain 19 270 2.4E-36 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 Pfam PF13360 PQQ-like domain 518 714 4.2E-13 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 Gene3D G3DSA:3.30.200.20 9 106 2.9E-12 T 28-03-2018 SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 SUPERFAMILY SSF56112 13 295 3.24E-60 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS29465 9c1ad3c03fbbff89e31e279c154f4b9a 784 SUPERFAMILY SSF50998 443 743 1.3E-18 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD44_RS23215 e7807a735447992e35dac777527a8824 165 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 15 133 3.0E-22 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III SMD44_RS35750 f21dad8a747bfb9efa9cedc65dd4a031 410 Pfam PF14594 Siphovirus ReqiPepy6 Gp37-like protein 12 376 6.4E-59 T 28-03-2018 IPR029432 Siphovirus Gp37-like protein SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 SUPERFAMILY SSF56719 42 499 7.19E-165 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 Gene3D G3DSA:1.10.268.10 357 499 4.9E-46 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 43 484 7.8E-149 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 669 714 1.3E-6 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 740 771 0.0023 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 Gene3D G3DSA:3.90.199.10 45 225 3.0E-80 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 Gene3D G3DSA:2.120.10.90 512 778 1.6E-52 T 28-03-2018 SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 SMART SM00434 22 477 6.1E-255 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 SUPERFAMILY SSF101904 514 775 2.49E-41 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SMD44_RS31615 4f2a089b6cc962c2bb1221b3ca80c658 817 Gene3D G3DSA:3.30.1360.40 248 345 1.8E-27 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMD44_RS29015 c273b4e2ec31b87ca87cba554f271156 311 Gene3D G3DSA:1.20.1270.70 17 77 0.003 T 28-03-2018 SMD44_RS32170 168a2946f7dad5e8de033e9fea9265f6 552 Pfam PF00501 AMP-binding enzyme 45 453 1.2E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS32170 168a2946f7dad5e8de033e9fea9265f6 552 Gene3D G3DSA:3.40.50.980 204 365 5.3E-39 T 28-03-2018 SMD44_RS32170 168a2946f7dad5e8de033e9fea9265f6 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS32170 168a2946f7dad5e8de033e9fea9265f6 552 Gene3D G3DSA:2.30.38.10 366 446 2.0E-15 T 28-03-2018 SMD44_RS32170 168a2946f7dad5e8de033e9fea9265f6 552 Gene3D G3DSA:3.40.50.980 35 203 1.8E-33 T 28-03-2018 SMD44_RS32170 168a2946f7dad5e8de033e9fea9265f6 552 SUPERFAMILY SSF56801 27 549 4.19E-133 T 28-03-2018 SMD44_RS32170 168a2946f7dad5e8de033e9fea9265f6 552 Gene3D G3DSA:3.30.300.30 447 549 6.7E-32 T 28-03-2018 SMD44_RS32170 168a2946f7dad5e8de033e9fea9265f6 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 462 537 2.5E-24 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMD44_RS25025 4b570f816e892234299d5e52324cf7cb 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25025 4b570f816e892234299d5e52324cf7cb 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.431 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25025 4b570f816e892234299d5e52324cf7cb 184 SUPERFAMILY SSF56770 9 154 1.24E-65 T 28-03-2018 SMD44_RS25025 4b570f816e892234299d5e52324cf7cb 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 4.6E-25 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25025 4b570f816e892234299d5e52324cf7cb 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 4.4E-70 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25025 4b570f816e892234299d5e52324cf7cb 184 Gene3D G3DSA:3.40.50.700 12 173 1.9E-43 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS30430 02c878ad73d4c3454a2e1fb118264e1c 454 ProSitePatterns PS01219 Ammonium transporters signature. 173 198 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 SMD44_RS30430 02c878ad73d4c3454a2e1fb118264e1c 454 Gene3D G3DSA:1.10.3430.10 10 399 7.1E-130 T 28-03-2018 SMD44_RS30430 02c878ad73d4c3454a2e1fb118264e1c 454 SUPERFAMILY SSF111352 15 399 3.4E-121 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 SMD44_RS30430 02c878ad73d4c3454a2e1fb118264e1c 454 Pfam PF00909 Ammonium Transporter Family 21 418 1.5E-124 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 SMD44_RS30430 02c878ad73d4c3454a2e1fb118264e1c 454 TIGRFAM TIGR00836 amt: ammonium transporter 18 418 9.5E-133 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 SMD44_RS23300 3b42d81e3d888922efdc291d2f156d2e 113 Pfam PF01740 STAS domain 12 108 4.1E-17 T 28-03-2018 IPR002645 STAS domain SMD44_RS23300 3b42d81e3d888922efdc291d2f156d2e 113 SUPERFAMILY SSF52091 3 110 1.22E-30 T 28-03-2018 IPR002645 STAS domain SMD44_RS23300 3b42d81e3d888922efdc291d2f156d2e 113 Gene3D G3DSA:3.30.750.24 1 113 2.9E-23 T 28-03-2018 IPR002645 STAS domain SMD44_RS23300 3b42d81e3d888922efdc291d2f156d2e 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 107 1.3E-32 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD44_RS06445 3785cf78f07dfd82a1a75e341e3e1634 164 Gene3D G3DSA:1.25.40.10 1 161 6.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS34770 c0f64cb6fd84d24da07d7d3233be5f94 404 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 211 218 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMD44_RS34770 c0f64cb6fd84d24da07d7d3233be5f94 404 SUPERFAMILY SSF51658 67 249 3.14E-25 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS34770 c0f64cb6fd84d24da07d7d3233be5f94 404 Pfam PF01261 Xylose isomerase-like TIM barrel 54 236 2.4E-11 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS34770 c0f64cb6fd84d24da07d7d3233be5f94 404 Gene3D G3DSA:3.20.20.150 38 399 2.4E-34 T 28-03-2018 SMD44_RS37520 e4bf3b06080fa682a35e63d85b55510a 506 Gene3D G3DSA:1.10.510.10 96 300 3.6E-21 T 28-03-2018 SMD44_RS37520 e4bf3b06080fa682a35e63d85b55510a 506 SUPERFAMILY SSF56112 53 307 2.5E-44 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS37520 e4bf3b06080fa682a35e63d85b55510a 506 Pfam PF02467 Transcription factor WhiB 418 482 3.7E-21 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS37520 e4bf3b06080fa682a35e63d85b55510a 506 Pfam PF01636 Phosphotransferase enzyme family 71 300 1.1E-31 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS37520 e4bf3b06080fa682a35e63d85b55510a 506 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 409 491 17.225 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 SUPERFAMILY SSF46785 2 86 1.25E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 Gene3D G3DSA:3.40.190.10 176 269 1.2E-10 T 28-03-2018 SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 Gene3D G3DSA:3.40.190.10 88 175 6.2E-17 T 28-03-2018 SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 SUPERFAMILY SSF53850 104 217 1.45E-17 T 28-03-2018 SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 Pfam PF03466 LysR substrate binding domain 87 217 1.7E-17 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 Gene3D G3DSA:1.10.10.10 1 83 1.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06395 4d3640d064667e10d79b2e98373edc93 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.5E-24 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS31980 35f9630a1b4e3c4e651ff8f1f5c1b931 197 Pfam PF00753 Metallo-beta-lactamase superfamily 28 96 5.2E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS31980 35f9630a1b4e3c4e651ff8f1f5c1b931 197 SMART SM00849 28 185 1.5E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS31980 35f9630a1b4e3c4e651ff8f1f5c1b931 197 Gene3D G3DSA:3.60.15.10 5 195 1.9E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS31980 35f9630a1b4e3c4e651ff8f1f5c1b931 197 SUPERFAMILY SSF56281 25 190 5.24E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS00195 028b2677856c15c91025a492565e2c95 100 Pfam PF00550 Phosphopantetheine attachment site 19 85 3.0E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS00195 028b2677856c15c91025a492565e2c95 100 Gene3D G3DSA:1.10.1200.10 3 99 5.4E-15 T 28-03-2018 SMD44_RS00195 028b2677856c15c91025a492565e2c95 100 SUPERFAMILY SSF47336 11 92 1.57E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS32085 71a1ec45dfa065d44762c1c2fe91eb03 107 SUPERFAMILY SSF101386 4 106 1.25E-32 T 28-03-2018 SMD44_RS32085 71a1ec45dfa065d44762c1c2fe91eb03 107 Gene3D G3DSA:1.10.287.1080 1 107 1.0E-23 T 28-03-2018 SMD44_RS32085 71a1ec45dfa065d44762c1c2fe91eb03 107 PIRSF PIRSF029826 2 107 7.5E-40 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 SMD44_RS32085 71a1ec45dfa065d44762c1c2fe91eb03 107 Pfam PF12643 MazG-like family 35 105 1.7E-11 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 SMD44_RS31765 91b2066fdb1551516deea69cc8d36aa2 240 Pfam PF02669 K+-transporting ATPase, c chain 14 233 1.3E-60 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMD44_RS31765 91b2066fdb1551516deea69cc8d36aa2 240 PIRSF PIRSF001296 8 239 9.0E-61 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMD44_RS31765 91b2066fdb1551516deea69cc8d36aa2 240 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 235 30.374 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMD44_RS21690 edd4d5664a3618c905018a7c69162df7 337 Gene3D G3DSA:1.10.620.20 25 317 5.9E-86 T 28-03-2018 SMD44_RS21690 edd4d5664a3618c905018a7c69162df7 337 Pfam PF05138 Phenylacetic acid catabolic protein 43 317 1.1E-107 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 SMD44_RS21690 edd4d5664a3618c905018a7c69162df7 337 SUPERFAMILY SSF47240 53 296 4.06E-84 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS21690 edd4d5664a3618c905018a7c69162df7 337 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 33 321 4.3E-159 T 28-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 SMD44_RS41870 ac79eebfdcbcc5474a336de97fb94606 278 Pfam PF12697 Alpha/beta hydrolase family 23 265 4.3E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS41870 ac79eebfdcbcc5474a336de97fb94606 278 SUPERFAMILY SSF53474 3 272 2.16E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS41870 ac79eebfdcbcc5474a336de97fb94606 278 PRINTS PR00412 Epoxide hydrolase signature 27 45 7.5E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS41870 ac79eebfdcbcc5474a336de97fb94606 278 PRINTS PR00412 Epoxide hydrolase signature 248 270 7.5E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS41870 ac79eebfdcbcc5474a336de97fb94606 278 PRINTS PR00412 Epoxide hydrolase signature 47 62 7.5E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS41870 ac79eebfdcbcc5474a336de97fb94606 278 Gene3D G3DSA:3.40.50.1820 1 277 5.1E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27075 4c0d8a84ae6df00e69c6cfd70f140da6 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 1.0E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS27075 4c0d8a84ae6df00e69c6cfd70f140da6 128 Gene3D G3DSA:3.10.180.10 2 128 2.4E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS27075 4c0d8a84ae6df00e69c6cfd70f140da6 128 SUPERFAMILY SSF54593 1 124 6.19E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS33340 2a67ca5bcf6e877a30f3570feb221e76 92 Gene3D G3DSA:3.30.70.930 1 91 3.3E-10 T 28-03-2018 IPR029756 MTH1187/YkoF-like SMD44_RS33340 2a67ca5bcf6e877a30f3570feb221e76 92 SUPERFAMILY SSF89957 3 77 5.1E-9 T 28-03-2018 IPR029756 MTH1187/YkoF-like SMD44_RS04645 54c6141b32649926c0542b7d7464a4de 194 Gene3D G3DSA:3.40.50.300 18 183 1.7E-7 T 28-03-2018 SMD44_RS04645 54c6141b32649926c0542b7d7464a4de 194 Pfam PF01695 IstB-like ATP binding protein 57 163 6.7E-10 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 SMD44_RS04645 54c6141b32649926c0542b7d7464a4de 194 SUPERFAMILY SSF52540 55 177 1.78E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS07285 1cc477d8fd7df5b780126199243ed2d4 166 Pfam PF01381 Helix-turn-helix 13 69 1.3E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS07285 1cc477d8fd7df5b780126199243ed2d4 166 SUPERFAMILY SSF47413 4 75 2.96E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS07285 1cc477d8fd7df5b780126199243ed2d4 166 Gene3D G3DSA:1.10.260.40 1 71 2.7E-12 T 28-03-2018 SMD44_RS07285 1cc477d8fd7df5b780126199243ed2d4 166 SMART SM00530 12 69 2.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS32125 d1324154741127edae6fe5071eb0be43 334 SUPERFAMILY SSF51735 5 140 5.3E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS32125 d1324154741127edae6fe5071eb0be43 334 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 5 316 8.7E-61 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS32125 d1324154741127edae6fe5071eb0be43 334 Gene3D G3DSA:1.10.1040.10 177 328 8.3E-29 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS32125 d1324154741127edae6fe5071eb0be43 334 Pfam PF02558 Ketopantoate reductase PanE/ApbA 7 152 5.5E-36 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS32125 d1324154741127edae6fe5071eb0be43 334 Gene3D G3DSA:3.40.50.720 5 176 1.0E-29 T 28-03-2018 SMD44_RS32125 d1324154741127edae6fe5071eb0be43 334 SUPERFAMILY SSF48179 176 315 2.38E-21 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS32125 d1324154741127edae6fe5071eb0be43 334 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 176 314 4.3E-20 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS31570 6d3ec2c5a23b69e4b96dcd379f5b6032 530 Pfam PF00474 Sodium:solute symporter family 38 453 2.7E-84 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS10360 d01568b0722cfe544453c14c6d72522c 453 Gene3D G3DSA:2.30.40.10 1 84 7.2E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS10360 d01568b0722cfe544453c14c6d72522c 453 Pfam PF01979 Amidohydrolase family 68 413 9.9E-57 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS10360 d01568b0722cfe544453c14c6d72522c 453 SUPERFAMILY SSF51338 11 70 7.27E-29 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS10360 d01568b0722cfe544453c14c6d72522c 453 SUPERFAMILY SSF51338 365 439 7.27E-29 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS10360 d01568b0722cfe544453c14c6d72522c 453 SUPERFAMILY SSF51556 70 365 6.01E-80 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS10360 d01568b0722cfe544453c14c6d72522c 453 Gene3D G3DSA:3.20.20.140 85 381 1.2E-50 T 28-03-2018 SMD44_RS29055 40d67bae0cf4fae46e66552170f14d1f 158 SMART SM00347 34 137 1.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS29055 40d67bae0cf4fae46e66552170f14d1f 158 Pfam PF12802 MarR family 41 100 5.0E-12 T 28-03-2018 SMD44_RS29055 40d67bae0cf4fae46e66552170f14d1f 158 Gene3D G3DSA:1.10.10.10 7 158 6.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29055 40d67bae0cf4fae46e66552170f14d1f 158 SUPERFAMILY SSF46785 7 152 9.9E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05025 153e0aa9ef7e329e5b0adf8164834a26 281 SUPERFAMILY SSF56235 50 263 2.85E-52 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS05025 153e0aa9ef7e329e5b0adf8164834a26 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 275 47.285 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 SMD44_RS05025 153e0aa9ef7e329e5b0adf8164834a26 281 Pfam PF00227 Proteasome subunit 52 230 5.9E-35 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMD44_RS05025 153e0aa9ef7e329e5b0adf8164834a26 281 Gene3D G3DSA:3.60.20.10 49 274 1.4E-45 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS05025 153e0aa9ef7e329e5b0adf8164834a26 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 269 7.0E-106 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 SMD44_RS02715 3995382bd3bd3f8bbe79ed235a8b490e 364 Gene3D G3DSA:3.20.20.10 7 244 2.3E-44 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS02715 3995382bd3bd3f8bbe79ed235a8b490e 364 SUPERFAMILY SSF51419 17 239 8.9E-34 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS02715 3995382bd3bd3f8bbe79ed235a8b490e 364 Pfam PF01168 Alanine racemase, N-terminal domain 16 239 6.5E-29 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS02715 3995382bd3bd3f8bbe79ed235a8b490e 364 SMART SM01119 254 347 2.2E-23 T 28-03-2018 IPR026956 D-serine dehydratase-like domain SMD44_RS02715 3995382bd3bd3f8bbe79ed235a8b490e 364 Pfam PF14031 Putative serine dehydratase domain 254 346 6.9E-16 T 28-03-2018 IPR026956 D-serine dehydratase-like domain SMD44_RS14780 f90d1584e61c667db8cf42fcbe6be3b5 636 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 297 3.4E-48 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS14780 f90d1584e61c667db8cf42fcbe6be3b5 636 Gene3D G3DSA:3.40.50.2300 465 636 6.5E-50 T 28-03-2018 SMD44_RS14780 f90d1584e61c667db8cf42fcbe6be3b5 636 Gene3D G3DSA:1.10.3470.10 8 305 3.2E-36 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS14780 f90d1584e61c667db8cf42fcbe6be3b5 636 SUPERFAMILY SSF53822 340 635 2.91E-89 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS14780 f90d1584e61c667db8cf42fcbe6be3b5 636 Gene3D G3DSA:3.40.50.2300 360 464 6.1E-27 T 28-03-2018 SMD44_RS14780 f90d1584e61c667db8cf42fcbe6be3b5 636 Pfam PF13407 Periplasmic binding protein domain 362 615 2.4E-64 T 28-03-2018 IPR025997 Periplasmic binding protein SMD44_RS43000 708fa5fdb9fd2911cbc2dd7008a059b1 145 Gene3D G3DSA:1.10.10.10 33 78 9.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS43000 708fa5fdb9fd2911cbc2dd7008a059b1 145 Gene3D G3DSA:1.10.10.10 79 129 8.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS37200 55bd7cc8d78d0deaab60b288539d0f8a 351 Pfam PF00248 Aldo/keto reductase family 28 328 5.1E-42 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS37200 55bd7cc8d78d0deaab60b288539d0f8a 351 Gene3D G3DSA:3.20.20.100 14 329 8.6E-60 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS37200 55bd7cc8d78d0deaab60b288539d0f8a 351 SUPERFAMILY SSF51430 16 326 4.32E-61 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS17740 7a69a251eb0583056116e35a9f311398 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 124 1.2E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS17740 7a69a251eb0583056116e35a9f311398 132 Gene3D G3DSA:3.10.180.10 4 131 6.9E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS17740 7a69a251eb0583056116e35a9f311398 132 SUPERFAMILY SSF54593 9 129 2.01E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS22225 ac7a83786d941d436c001475e6ae16b5 161 SUPERFAMILY SSF46785 8 141 1.23E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22225 ac7a83786d941d436c001475e6ae16b5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS22225 ac7a83786d941d436c001475e6ae16b5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS22225 ac7a83786d941d436c001475e6ae16b5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS22225 ac7a83786d941d436c001475e6ae16b5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS22225 ac7a83786d941d436c001475e6ae16b5 161 Pfam PF12802 MarR family 37 93 1.1E-8 T 28-03-2018 SMD44_RS22225 ac7a83786d941d436c001475e6ae16b5 161 SMART SM00347 30 129 1.7E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS22225 ac7a83786d941d436c001475e6ae16b5 161 Gene3D G3DSA:1.10.10.10 2 143 4.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36015 82c8836f410a83e933b3b0b98033ddae 118 Pfam PF04237 YjbR 12 98 1.0E-17 T 28-03-2018 IPR007351 Uncharacterised protein YjbR SMD44_RS36015 82c8836f410a83e933b3b0b98033ddae 118 SUPERFAMILY SSF142906 1 114 2.75E-21 T 28-03-2018 SMD44_RS36015 82c8836f410a83e933b3b0b98033ddae 118 Gene3D G3DSA:3.30.1460.30 3 102 3.0E-14 T 28-03-2018 SMD44_RS23180 5f8941c4a0cf129dcb5414c5b0bd58d4 278 SUPERFAMILY SSF81301 25 83 7.27E-8 T 28-03-2018 SMD44_RS23180 5f8941c4a0cf129dcb5414c5b0bd58d4 278 Gene3D G3DSA:3.30.460.10 24 185 4.5E-10 T 28-03-2018 SMD44_RS21390 108659d73ee624b5a82fa46f919a42b1 238 Pfam PF03861 ANTAR domain 180 231 2.6E-14 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS21390 108659d73ee624b5a82fa46f919a42b1 238 Pfam PF13185 GAF domain 25 165 3.7E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS21390 108659d73ee624b5a82fa46f919a42b1 238 PIRSF PIRSF036625 2 236 1.7E-32 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS21390 108659d73ee624b5a82fa46f919a42b1 238 SMART SM00065 25 175 0.0022 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS21390 108659d73ee624b5a82fa46f919a42b1 238 SUPERFAMILY SSF55781 25 177 2.06E-13 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS21390 108659d73ee624b5a82fa46f919a42b1 238 SMART SM01012 177 232 1.6E-14 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS21390 108659d73ee624b5a82fa46f919a42b1 238 Gene3D G3DSA:3.30.450.40 6 181 2.2E-18 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS21390 108659d73ee624b5a82fa46f919a42b1 238 Gene3D G3DSA:1.10.10.10 182 233 3.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36730 11f1e3d30af79a1aac27ab2135154e46 189 SUPERFAMILY SSF46689 2 68 2.36E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS36730 11f1e3d30af79a1aac27ab2135154e46 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 4.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS36730 11f1e3d30af79a1aac27ab2135154e46 189 Gene3D G3DSA:1.10.357.10 60 183 1.7E-6 T 28-03-2018 SMD44_RS36730 11f1e3d30af79a1aac27ab2135154e46 189 Gene3D G3DSA:1.10.10.60 5 59 5.7E-15 T 28-03-2018 SMD44_RS24865 168b2e6bf7347a3bcc7e2af2087264b3 129 Gene3D G3DSA:1.10.3230.10 5 118 1.3E-4 T 28-03-2018 SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 SUPERFAMILY SSF53822 73 349 1.61E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 Gene3D G3DSA:1.10.10.10 11 30 0.28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 Gene3D G3DSA:3.40.50.2300 184 350 1.4E-48 T 28-03-2018 SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 ProSitePatterns PS00356 LacI-type HTH domain signature. 19 37 - T 28-03-2018 SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 SMART SM00354 16 83 9.4E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 Pfam PF13377 Periplasmic binding protein-like domain 185 347 1.6E-36 T 28-03-2018 SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 Gene3D G3DSA:3.40.50.2300 70 183 9.0E-28 T 28-03-2018 SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 61 1.9E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 Gene3D G3DSA:1.10.260.40 31 69 9.3E-16 T 28-03-2018 SMD44_RS05285 dfe1bacc776f4a9879f593dfe6e6a736 354 SUPERFAMILY SSF47413 17 62 2.49E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS24645 232c2635866bbc445fc31097f0e36d64 161 Pfam PF11292 Protein of unknown function (DUF3093) 3 103 8.2E-5 T 28-03-2018 IPR021443 Protein of unknown function DUF3093 SMD44_RS33235 f1c877dbf2502ba85db413a8f1c54585 299 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 205 5.9E-15 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS33235 f1c877dbf2502ba85db413a8f1c54585 299 Gene3D G3DSA:3.40.50.720 1 284 2.8E-31 T 28-03-2018 SMD44_RS33235 f1c877dbf2502ba85db413a8f1c54585 299 SUPERFAMILY SSF51735 1 277 7.24E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS16930 af6701c7984d822a5815193a7986c6ae 290 Gene3D G3DSA:1.10.10.60 59 135 1.1E-7 T 28-03-2018 SMD44_RS16930 af6701c7984d822a5815193a7986c6ae 290 Gene3D G3DSA:1.10.10.10 4 48 0.0045 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13245 8539b058fdb8aa912d94db11842e69f3 342 Pfam PF01595 Domain of unknown function DUF21 9 198 4.0E-38 T 28-03-2018 IPR002550 Domain of unknown function DUF21 SMD44_RS13245 8539b058fdb8aa912d94db11842e69f3 342 SMART SM00116 225 273 18.0 T 28-03-2018 IPR000644 CBS domain SMD44_RS13245 8539b058fdb8aa912d94db11842e69f3 342 SMART SM00116 285 333 0.15 T 28-03-2018 IPR000644 CBS domain SMD44_RS13245 8539b058fdb8aa912d94db11842e69f3 342 Gene3D G3DSA:3.20.20.70 159 336 1.0E-22 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13245 8539b058fdb8aa912d94db11842e69f3 342 Pfam PF00571 CBS domain 285 333 6.4E-4 T 28-03-2018 IPR000644 CBS domain SMD44_RS13245 8539b058fdb8aa912d94db11842e69f3 342 SUPERFAMILY SSF54631 206 334 1.89E-20 T 28-03-2018 SMD44_RS01975 e410bc82218138efadf354b0f4964a81 263 Gene3D G3DSA:3.60.10.10 23 261 1.7E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS01975 e410bc82218138efadf354b0f4964a81 263 SUPERFAMILY SSF56219 29 260 1.31E-33 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS01975 e410bc82218138efadf354b0f4964a81 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 31 253 6.6E-14 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS03160 631a8c6cf9fee8478ec4d8a355c49fbc 258 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS03160 631a8c6cf9fee8478ec4d8a355c49fbc 258 Pfam PF00005 ABC transporter 18 156 4.0E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS03160 631a8c6cf9fee8478ec4d8a355c49fbc 258 SUPERFAMILY SSF52540 2 221 4.7E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS03160 631a8c6cf9fee8478ec4d8a355c49fbc 258 Gene3D G3DSA:3.40.50.300 1 256 9.6E-60 T 28-03-2018 SMD44_RS03160 631a8c6cf9fee8478ec4d8a355c49fbc 258 SMART SM00382 26 204 5.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS25005 9eee4e6339aca162d2b5ff06a13709a1 560 Gene3D G3DSA:3.40.50.1390 7 171 6.9E-21 T 28-03-2018 SMD44_RS25005 9eee4e6339aca162d2b5ff06a13709a1 560 Pfam PF00239 Resolvase, N terminal domain 14 163 1.6E-14 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS25005 9eee4e6339aca162d2b5ff06a13709a1 560 SUPERFAMILY SSF53041 13 163 4.58E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS25005 9eee4e6339aca162d2b5ff06a13709a1 560 SMART SM00857 11 164 5.3E-13 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD44_RS25005 9eee4e6339aca162d2b5ff06a13709a1 560 Pfam PF07508 Recombinase 190 345 8.6E-5 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 SMD44_RS09670 c4eb325126d5b32f1eca005814ebbfc3 411 SUPERFAMILY SSF53383 33 345 3.94E-59 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS09670 c4eb325126d5b32f1eca005814ebbfc3 411 Gene3D G3DSA:3.90.1150.10 247 354 2.7E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS09670 c4eb325126d5b32f1eca005814ebbfc3 411 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 216 229 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMD44_RS09670 c4eb325126d5b32f1eca005814ebbfc3 411 Gene3D G3DSA:3.40.640.10 53 246 4.1E-24 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS09670 c4eb325126d5b32f1eca005814ebbfc3 411 Pfam PF00155 Aminotransferase class I and II 38 344 3.1E-32 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS15175 dafef970cc653387b40bb8105333e2a7 312 Pfam PF01177 Asp/Glu/Hydantoin racemase 65 227 3.8E-7 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS15175 dafef970cc653387b40bb8105333e2a7 312 Gene3D G3DSA:3.40.50.2300 117 258 3.8E-9 T 28-03-2018 SMD44_RS08460 d931341acf22f11782660f0ffca48dd4 217 Gene3D G3DSA:1.20.950.20 20 217 5.0E-32 T 28-03-2018 SMD44_RS08460 d931341acf22f11782660f0ffca48dd4 217 SUPERFAMILY SSF81342 21 216 2.59E-25 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SMD44_RS08460 d931341acf22f11782660f0ffca48dd4 217 Pfam PF01292 Prokaryotic cytochrome b561 26 194 2.9E-12 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 SMD44_RS25910 616ab41c6ee3df7da598560a2003833b 261 Gene3D G3DSA:3.40.225.10 19 256 2.0E-67 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMD44_RS25910 616ab41c6ee3df7da598560a2003833b 261 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 33 212 3.2E-49 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMD44_RS25910 616ab41c6ee3df7da598560a2003833b 261 SUPERFAMILY SSF53639 26 243 7.46E-68 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMD44_RS25910 616ab41c6ee3df7da598560a2003833b 261 SMART SM01007 32 212 4.2E-57 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMD44_RS21440 7a1c63db63404e4b8babd4496d493b05 261 SUPERFAMILY SSF63817 99 247 1.16E-28 T 28-03-2018 IPR023365 Sortase domain SMD44_RS21440 7a1c63db63404e4b8babd4496d493b05 261 TIGRFAM TIGR01076 sortase_fam: sortase 107 243 3.4E-12 T 28-03-2018 IPR005754 Sortase family SMD44_RS21440 7a1c63db63404e4b8babd4496d493b05 261 Pfam PF04203 Sortase family 110 244 1.4E-24 T 28-03-2018 IPR005754 Sortase family SMD44_RS21440 7a1c63db63404e4b8babd4496d493b05 261 Gene3D G3DSA:2.40.260.10 1 259 1.9E-36 T 28-03-2018 IPR023365 Sortase domain SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 SUPERFAMILY SSF57716 11 46 1.37E-11 T 28-03-2018 SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 Gene3D G3DSA:1.10.8.60 318 410 3.8E-32 T 28-03-2018 SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 Gene3D G3DSA:3.40.50.300 53 316 7.3E-68 T 28-03-2018 SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 412 2.2E-196 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 SMART SM00382 114 334 3.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 SMART SM00994 10 49 1.1E-23 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 SUPERFAMILY SSF52540 58 403 7.52E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 SMART SM01086 318 412 2.1E-30 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 416 52.363 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 312 4.2E-51 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMD44_RS14140 3c0c5612980e55022601cd7af6097263 428 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 395 2.0E-15 T 28-03-2018 IPR019489 Clp ATPase, C-terminal SMD44_RS11830 c442880d21ed60b5b267c7ec1c4c7945 234 Gene3D G3DSA:1.10.357.10 70 197 2.9E-12 T 28-03-2018 SMD44_RS11830 c442880d21ed60b5b267c7ec1c4c7945 234 Gene3D G3DSA:1.10.10.60 51 69 1.2E-11 T 28-03-2018 SMD44_RS11830 c442880d21ed60b5b267c7ec1c4c7945 234 Gene3D G3DSA:1.10.10.60 1 50 2.1E-16 T 28-03-2018 SMD44_RS11830 c442880d21ed60b5b267c7ec1c4c7945 234 SUPERFAMILY SSF46689 5 79 2.92E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS11830 c442880d21ed60b5b267c7ec1c4c7945 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11830 c442880d21ed60b5b267c7ec1c4c7945 234 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS11830 c442880d21ed60b5b267c7ec1c4c7945 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS11830 c442880d21ed60b5b267c7ec1c4c7945 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 Gene3D G3DSA:3.40.50.2300 1 160 1.1E-49 T 28-03-2018 SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 105 118 8.0E-20 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 8.0E-20 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 8.0E-20 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 8.0E-20 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 8.0E-20 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 SUPERFAMILY SSF52788 3 153 3.4E-46 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 150 1.0E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS20885 118c3919b740edb15462363a0ccec2a9 162 SMART SM00226 3 152 1.2E-49 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS34265 cffa1ddd95b7c7c3642740e9ad8b59b4 382 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 50 377 2.5E-107 T 28-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 SMD44_RS34265 cffa1ddd95b7c7c3642740e9ad8b59b4 382 SUPERFAMILY SSF55909 45 377 4.46E-107 T 28-03-2018 SMD44_RS34265 cffa1ddd95b7c7c3642740e9ad8b59b4 382 Gene3D G3DSA:3.75.10.10 37 382 4.2E-118 T 28-03-2018 SMD44_RS25715 c0e65cd63e63f967f29c51f3515fc42c 170 Gene3D G3DSA:3.40.50.300 10 168 5.5E-47 T 28-03-2018 SMD44_RS25715 c0e65cd63e63f967f29c51f3515fc42c 170 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 22 141 4.4E-25 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SMD44_RS25715 c0e65cd63e63f967f29c51f3515fc42c 170 SUPERFAMILY SSF52540 34 152 1.11E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS25715 c0e65cd63e63f967f29c51f3515fc42c 170 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 18 139 8.7E-29 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SMD44_RS43570 3198f31ecd81a90b979945bd44697fae 247 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 41 218 6.8E-29 T 28-03-2018 IPR013382 CRISPR-associated protein Cse2 SMD44_RS43570 3198f31ecd81a90b979945bd44697fae 247 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 20 220 2.1E-31 T 28-03-2018 IPR013382 CRISPR-associated protein Cse2 SMD44_RS18005 0113efc31474f89f438301441b61c858 162 SUPERFAMILY SSF102405 1 157 1.83E-13 T 28-03-2018 SMD44_RS18005 0113efc31474f89f438301441b61c858 162 Gene3D G3DSA:3.40.50.450 1 161 4.7E-34 T 28-03-2018 SMD44_RS15790 ab2bec3c28ba68b11d808232dacda58f 269 SUPERFAMILY SSF54211 125 257 1.48E-16 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMD44_RS15790 ab2bec3c28ba68b11d808232dacda58f 269 Gene3D G3DSA:3.30.230.10 38 267 2.9E-33 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD44_RS15790 ab2bec3c28ba68b11d808232dacda58f 269 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 160 250 3.4E-7 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 SMD44_RS30770 cce75f8b3c85f37ea3aa64a177fdf98c 534 Pfam PF13556 PucR C-terminal helix-turn-helix domain 470 528 3.8E-22 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS30770 cce75f8b3c85f37ea3aa64a177fdf98c 534 Pfam PF07905 Purine catabolism regulatory protein-like family 8 126 2.2E-33 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain SMD44_RS30770 cce75f8b3c85f37ea3aa64a177fdf98c 534 Gene3D G3DSA:1.10.10.60 455 506 6.8E-6 T 28-03-2018 SMD44_RS28360 59224cb7c35e7ae453affd6caca867ad 329 Gene3D G3DSA:1.10.3720.10 39 328 1.2E-47 T 28-03-2018 SMD44_RS28360 59224cb7c35e7ae453affd6caca867ad 329 SUPERFAMILY SSF161098 86 314 1.27E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS28360 59224cb7c35e7ae453affd6caca867ad 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 318 7.4E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS35095 1b4699a865cd644e8da69940c646714c 393 Gene3D G3DSA:3.30.420.40 241 375 5.2E-24 T 28-03-2018 SMD44_RS35095 1b4699a865cd644e8da69940c646714c 393 Gene3D G3DSA:3.30.420.40 1 181 4.4E-49 T 28-03-2018 SMD44_RS35095 1b4699a865cd644e8da69940c646714c 393 SUPERFAMILY SSF53067 143 328 1.51E-11 T 28-03-2018 SMD44_RS35095 1b4699a865cd644e8da69940c646714c 393 SUPERFAMILY SSF53067 67 110 1.51E-11 T 28-03-2018 SMD44_RS35095 1b4699a865cd644e8da69940c646714c 393 SUPERFAMILY SSF53067 1 35 1.51E-11 T 28-03-2018 SMD44_RS35095 1b4699a865cd644e8da69940c646714c 393 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 369 34.943 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 SMD44_RS35095 1b4699a865cd644e8da69940c646714c 393 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 368 1.5E-113 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 SMD44_RS02160 18e5e1a90b36f9611543af4dc20d68d9 138 Gene3D G3DSA:3.10.180.10 1 134 1.0E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS02160 18e5e1a90b36f9611543af4dc20d68d9 138 SUPERFAMILY SSF54593 7 124 6.33E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS08175 d01209d267809749e5727206d8690db7 104 Pfam PF13459 4Fe-4S single cluster domain 19 89 2.1E-18 T 28-03-2018 SMD44_RS08175 d01209d267809749e5727206d8690db7 104 PRINTS PR00352 3Fe-4S ferredoxin signature 32 42 2.3E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS08175 d01209d267809749e5727206d8690db7 104 PRINTS PR00352 3Fe-4S ferredoxin signature 75 87 2.3E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS08175 d01209d267809749e5727206d8690db7 104 PRINTS PR00352 3Fe-4S ferredoxin signature 21 32 2.3E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD44_RS08175 d01209d267809749e5727206d8690db7 104 Gene3D G3DSA:3.30.70.20 16 95 1.3E-6 T 28-03-2018 SMD44_RS08175 d01209d267809749e5727206d8690db7 104 SUPERFAMILY SSF54862 18 89 4.19E-9 T 28-03-2018 SMD44_RS12355 1272d4ea8eba1b99742a4244f75dcb49 357 Gene3D G3DSA:1.50.10.10 60 331 6.9E-22 T 28-03-2018 SMD44_RS12355 1272d4ea8eba1b99742a4244f75dcb49 357 SUPERFAMILY SSF48208 29 342 3.74E-39 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS12355 1272d4ea8eba1b99742a4244f75dcb49 357 Gene3D G3DSA:1.50.10.20 9 59 1.7E-4 T 28-03-2018 SMD44_RS12355 1272d4ea8eba1b99742a4244f75dcb49 357 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 133 175 8.3 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 SMD44_RS12355 1272d4ea8eba1b99742a4244f75dcb49 357 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 68 86 0.0022 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 SMD44_RS05615 780d6721019e4ca064eec9f8468943c4 134 Gene3D G3DSA:3.30.350.10 34 134 1.6E-31 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS05615 780d6721019e4ca064eec9f8468943c4 134 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 58 85 2.0E-12 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS05615 780d6721019e4ca064eec9f8468943c4 134 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 109 125 2.0E-12 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD44_RS05615 780d6721019e4ca064eec9f8468943c4 134 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 57 75 - T 28-03-2018 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 SMD44_RS05615 780d6721019e4ca064eec9f8468943c4 134 Pfam PF00720 Subtilisin inhibitor-like 40 120 3.7E-25 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS05615 780d6721019e4ca064eec9f8468943c4 134 SUPERFAMILY SSF55399 41 134 2.09E-29 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS05615 780d6721019e4ca064eec9f8468943c4 134 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 43 122 1.0E-16 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 Gene3D G3DSA:3.40.50.1820 4 288 1.4E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 2.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 2.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 Pfam PF12697 Alpha/beta hydrolase family 36 274 6.0E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 PRINTS PR00412 Epoxide hydrolase signature 104 117 2.2E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 PRINTS PR00412 Epoxide hydrolase signature 258 280 2.2E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 PRINTS PR00412 Epoxide hydrolase signature 118 131 2.2E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 PRINTS PR00412 Epoxide hydrolase signature 59 74 2.2E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS18240 4089813568b4f6f7dd1d7c9e6df766f6 288 SUPERFAMILY SSF53474 32 283 4.22E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS22335 bb274821e708084c4c2fcf7154406ef4 186 SUPERFAMILY SSF160904 5 177 7.72E-43 T 28-03-2018 SMD44_RS22335 bb274821e708084c4c2fcf7154406ef4 186 Gene3D G3DSA:1.10.3300.10 2 180 2.7E-45 T 28-03-2018 IPR023286 ABATE domain SMD44_RS22335 bb274821e708084c4c2fcf7154406ef4 186 Pfam PF11706 CGNR zinc finger 136 178 4.4E-17 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS22335 bb274821e708084c4c2fcf7154406ef4 186 Pfam PF07336 Putative stress-induced transcription regulator 10 131 6.1E-21 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS35305 8d895e160618b149df2c79ecfc5ae045 393 SUPERFAMILY SSF110296 73 359 1.09E-36 T 28-03-2018 SMD44_RS35305 8d895e160618b149df2c79ecfc5ae045 393 Gene3D G3DSA:2.120.10.10 41 201 1.2E-17 T 28-03-2018 SMD44_RS35305 8d895e160618b149df2c79ecfc5ae045 393 Gene3D G3DSA:2.120.10.10 202 386 4.1E-18 T 28-03-2018 SMD44_RS05620 e075846b3089ca529a23f2e04a64ad66 241 SUPERFAMILY SSF69593 3 215 5.36E-52 T 28-03-2018 SMD44_RS05620 e075846b3089ca529a23f2e04a64ad66 241 SMART SM00563 35 154 8.4E-39 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS05620 e075846b3089ca529a23f2e04a64ad66 241 Pfam PF01553 Acyltransferase 21 151 6.1E-24 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS05620 e075846b3089ca529a23f2e04a64ad66 241 Gene3D G3DSA:3.40.1130.10 6 230 2.8E-56 T 28-03-2018 SMD44_RS02195 ea5a379421dfd79c450052d55eb00826 152 SUPERFAMILY SSF54427 2 146 1.35E-67 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS02195 ea5a379421dfd79c450052d55eb00826 152 Gene3D G3DSA:3.10.450.50 11 149 1.9E-59 T 28-03-2018 SMD44_RS02195 ea5a379421dfd79c450052d55eb00826 152 Pfam PF07080 Protein of unknown function (DUF1348) 8 136 1.7E-61 T 28-03-2018 IPR009783 Protein of unknown function DUF1348 SMD44_RS20135 62e701f5ab0549459deb5b3dd0c3f71e 140 SUPERFAMILY SSF88723 5 124 4.77E-14 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS20135 62e701f5ab0549459deb5b3dd0c3f71e 140 Pfam PF01850 PIN domain 7 124 2.0E-10 T 28-03-2018 IPR002716 PIN domain SMD44_RS20135 62e701f5ab0549459deb5b3dd0c3f71e 140 Gene3D G3DSA:3.40.50.1010 2 138 3.9E-19 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS20135 62e701f5ab0549459deb5b3dd0c3f71e 140 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 130 11.694 T 28-03-2018 IPR022907 VapC family GO:0004540 SMD44_RS32805 051952fe1a4504e2d2947638c141b6a8 308 Gene3D G3DSA:1.10.3720.10 52 303 6.3E-29 T 28-03-2018 SMD44_RS32805 051952fe1a4504e2d2947638c141b6a8 308 SUPERFAMILY SSF161098 100 288 2.88E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS32805 051952fe1a4504e2d2947638c141b6a8 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 289 6.2E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS40140 9079a20786175a25ebdd447c0b927139 976 SUPERFAMILY SSF48452 649 752 6.64E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40140 9079a20786175a25ebdd447c0b927139 976 Gene3D G3DSA:1.25.40.10 350 833 7.3E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40140 9079a20786175a25ebdd447c0b927139 976 SUPERFAMILY SSF52540 18 110 4.61E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS40140 9079a20786175a25ebdd447c0b927139 976 SUPERFAMILY SSF52540 137 246 4.61E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS40140 9079a20786175a25ebdd447c0b927139 976 Gene3D G3DSA:3.40.50.300 20 195 2.9E-12 T 28-03-2018 SMD44_RS40140 9079a20786175a25ebdd447c0b927139 976 Pfam PF13191 AAA ATPase domain 20 170 6.9E-21 T 28-03-2018 SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 4.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 4.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 4.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 4.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 SUPERFAMILY SSF51735 4 257 7.77E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 257 2.2E-42 T 28-03-2018 SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 4.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 4.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 200 2.7E-4 T 28-03-2018 SMD44_RS01915 6d21ac7ee939e796b0e8d7c89d9a9ca6 264 Gene3D G3DSA:3.40.50.720 1 259 2.4E-60 T 28-03-2018 SMD44_RS37960 0826a807491f73e7895f2a55e6d5fb8a 395 Gene3D G3DSA:3.40.50.300 97 368 1.5E-8 T 28-03-2018 SMD44_RS37960 0826a807491f73e7895f2a55e6d5fb8a 395 SUPERFAMILY SSF52540 97 151 4.63E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37960 0826a807491f73e7895f2a55e6d5fb8a 395 SUPERFAMILY SSF52540 195 336 4.63E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS38595 5ac90f517496ead4d3a6432a641841c1 289 Gene3D G3DSA:1.10.1040.10 189 289 7.9E-32 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS38595 5ac90f517496ead4d3a6432a641841c1 289 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 286 4.0E-31 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS38595 5ac90f517496ead4d3a6432a641841c1 289 Gene3D G3DSA:3.40.50.720 2 188 3.4E-47 T 28-03-2018 SMD44_RS38595 5ac90f517496ead4d3a6432a641841c1 289 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 187 2.6E-55 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMD44_RS38595 5ac90f517496ead4d3a6432a641841c1 289 SUPERFAMILY SSF48179 190 288 2.38E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS38595 5ac90f517496ead4d3a6432a641841c1 289 SUPERFAMILY SSF51735 4 187 4.65E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS38595 5ac90f517496ead4d3a6432a641841c1 289 PIRSF PIRSF000105 2 289 3.0E-76 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMD44_RS11130 040195e458a5f11af241c7f1d6f4313c 515 Pfam PF01593 Flavin containing amine oxidoreductase 14 293 1.6E-13 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD44_RS11130 040195e458a5f11af241c7f1d6f4313c 515 SUPERFAMILY SSF51905 2 307 1.15E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11130 040195e458a5f11af241c7f1d6f4313c 515 SUPERFAMILY SSF51905 468 506 1.15E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS11130 040195e458a5f11af241c7f1d6f4313c 515 Gene3D G3DSA:3.50.50.60 2 507 2.0E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS41910 88abe78bea1e859dbb31c421310b4466 356 SUPERFAMILY SSF158745 17 216 3.66E-14 T 28-03-2018 SMD44_RS41910 88abe78bea1e859dbb31c421310b4466 356 Gene3D G3DSA:1.50.10.20 4 234 2.2E-13 T 28-03-2018 SMD44_RS18615 30a5e1963523afb0912deba39318e73b 377 Pfam PF01032 FecCD transport family 62 367 2.1E-78 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS18615 30a5e1963523afb0912deba39318e73b 377 SUPERFAMILY SSF81345 44 367 9.02E-70 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS18615 30a5e1963523afb0912deba39318e73b 377 Gene3D G3DSA:1.10.3470.10 46 374 3.2E-64 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS25860 b98f01b42f946f11d9999452e358b76e 592 Gene3D G3DSA:3.30.200.20 70 178 1.2E-22 T 28-03-2018 SMD44_RS25860 b98f01b42f946f11d9999452e358b76e 592 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 98 121 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS25860 b98f01b42f946f11d9999452e358b76e 592 SUPERFAMILY SSF56112 81 367 1.05E-69 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS25860 b98f01b42f946f11d9999452e358b76e 592 SMART SM00220 92 351 2.3E-60 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25860 b98f01b42f946f11d9999452e358b76e 592 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 215 227 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS25860 b98f01b42f946f11d9999452e358b76e 592 Pfam PF00069 Protein kinase domain 92 343 8.0E-48 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25860 b98f01b42f946f11d9999452e358b76e 592 Gene3D G3DSA:1.10.510.10 179 484 3.8E-48 T 28-03-2018 SMD44_RS12060 7af101ac43e70f7cd1f02fa2a989ae6e 282 SMART SM00382 52 238 3.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS12060 7af101ac43e70f7cd1f02fa2a989ae6e 282 Gene3D G3DSA:3.40.50.300 18 260 2.2E-53 T 28-03-2018 SMD44_RS12060 7af101ac43e70f7cd1f02fa2a989ae6e 282 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS12060 7af101ac43e70f7cd1f02fa2a989ae6e 282 Pfam PF00005 ABC transporter 43 190 2.9E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS12060 7af101ac43e70f7cd1f02fa2a989ae6e 282 SUPERFAMILY SSF52540 15 251 2.71E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS42855 14fd36ec3559c28f3757632db2f0e23b 249 Pfam PF03259 Roadblock/LC7 domain 114 198 6.2E-14 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS42855 14fd36ec3559c28f3757632db2f0e23b 249 Gene3D G3DSA:3.30.450.30 110 245 1.7E-25 T 28-03-2018 SMD44_RS42855 14fd36ec3559c28f3757632db2f0e23b 249 SUPERFAMILY SSF103196 113 241 6.98E-14 T 28-03-2018 SMD44_RS42855 14fd36ec3559c28f3757632db2f0e23b 249 SMART SM00960 114 202 2.5E-9 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 SMART SM00421 160 217 3.7E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 SUPERFAMILY SSF52172 3 134 4.27E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 SUPERFAMILY SSF46894 157 223 1.05E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 217 9.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 SMART SM00448 2 115 1.5E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 Gene3D G3DSA:3.40.50.2300 1 133 1.3E-37 T 28-03-2018 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 Pfam PF00072 Response regulator receiver domain 4 113 2.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 Gene3D G3DSA:1.10.10.10 134 222 4.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 2.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 2.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS19520 cf68062d115f36d429a20ff9a28f8505 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 2.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS02455 02ab0d5702dec5e6477badd43f5c81a3 681 Gene3D G3DSA:2.60.40.10 607 676 0.0036 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS02455 02ab0d5702dec5e6477badd43f5c81a3 681 SUPERFAMILY SSF55486 268 330 9.78E-6 T 28-03-2018 SMD44_RS02455 02ab0d5702dec5e6477badd43f5c81a3 681 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 90 398 1.5E-38 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD44_RS26085 65d2e78011130eab7eb738b2a73a057d 266 SUPERFAMILY SSF47090 201 265 2.55E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS26085 65d2e78011130eab7eb738b2a73a057d 266 Gene3D G3DSA:1.10.260.40 9 80 3.7E-10 T 28-03-2018 SMD44_RS26085 65d2e78011130eab7eb738b2a73a057d 266 SMART SM00530 21 76 5.4E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS26085 65d2e78011130eab7eb738b2a73a057d 266 Pfam PF13560 Helix-turn-helix domain 17 75 1.2E-12 T 28-03-2018 SMD44_RS26085 65d2e78011130eab7eb738b2a73a057d 266 SUPERFAMILY SSF47413 17 80 1.02E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS26085 65d2e78011130eab7eb738b2a73a057d 266 Gene3D G3DSA:1.10.101.10 191 266 7.2E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS26085 65d2e78011130eab7eb738b2a73a057d 266 Pfam PF01471 Putative peptidoglycan binding domain 211 262 6.5E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS02405 5daf933e3e2769cf4f74a52e5de61790 266 PIRSF PIRSF017393 1 266 2.1E-99 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS02405 5daf933e3e2769cf4f74a52e5de61790 266 SUPERFAMILY SSF53335 15 256 3.14E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS02405 5daf933e3e2769cf4f74a52e5de61790 266 Pfam PF04672 S-adenosyl methyltransferase 8 266 8.1E-113 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS02405 5daf933e3e2769cf4f74a52e5de61790 266 Gene3D G3DSA:3.40.50.150 2 266 1.2E-56 T 28-03-2018 SMD44_RS20105 acb1074370027942a01441054ab4fb7c 102 Gene3D G3DSA:1.10.1660.20 22 62 9.0E-6 T 28-03-2018 SMD44_RS01250 55475fbd063f224873e0e70a4186e671 449 Gene3D G3DSA:3.40.710.10 88 443 2.1E-73 T 28-03-2018 SMD44_RS01250 55475fbd063f224873e0e70a4186e671 449 SUPERFAMILY SSF56601 100 432 4.99E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS01250 55475fbd063f224873e0e70a4186e671 449 Pfam PF00144 Beta-lactamase 100 433 2.8E-54 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS02555 f9d4e9f0909705c614d01bcb4aa46d46 176 Pfam PF00583 Acetyltransferase (GNAT) family 19 132 5.3E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS02555 f9d4e9f0909705c614d01bcb4aa46d46 176 SUPERFAMILY SSF55729 1 138 3.77E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS02555 f9d4e9f0909705c614d01bcb4aa46d46 176 Gene3D G3DSA:3.40.630.30 1 173 9.1E-23 T 28-03-2018 SMD44_RS00360 bebdcaad177699bfa54c12eb9d1116c3 201 Pfam PF13586 Transposase DDE domain 87 159 6.1E-8 T 28-03-2018 IPR025668 Transposase DDE domain SMD44_RS16105 399e3e1c9d9f3885f45454a75bf39493 324 Gene3D G3DSA:3.40.50.150 30 193 1.0E-9 T 28-03-2018 SMD44_RS16105 399e3e1c9d9f3885f45454a75bf39493 324 Pfam PF13578 Methyltransferase domain 56 177 4.1E-14 T 28-03-2018 SMD44_RS16105 399e3e1c9d9f3885f45454a75bf39493 324 SUPERFAMILY SSF53335 32 181 1.04E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS17975 aed7a232dd48857b38c40af7482dafcc 167 Gene3D G3DSA:3.40.630.30 3 90 7.2E-13 T 28-03-2018 SMD44_RS17975 aed7a232dd48857b38c40af7482dafcc 167 Gene3D G3DSA:3.40.630.30 91 166 1.6E-13 T 28-03-2018 SMD44_RS17975 aed7a232dd48857b38c40af7482dafcc 167 SUPERFAMILY SSF55729 9 148 1.03E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS17975 aed7a232dd48857b38c40af7482dafcc 167 Pfam PF00583 Acetyltransferase (GNAT) family 63 136 7.2E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS40780 a39658503ed9e9f313a059776694a70f 246 SUPERFAMILY SSF53474 127 246 1.5E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS40780 a39658503ed9e9f313a059776694a70f 246 SUPERFAMILY SSF53474 22 96 1.5E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS40780 a39658503ed9e9f313a059776694a70f 246 Gene3D G3DSA:3.40.50.1820 1 246 2.3E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS02105 fcbb8b2f0d7dd903ab654b01925fa55a 206 Pfam PF01965 DJ-1/PfpI family 3 161 3.0E-28 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS02105 fcbb8b2f0d7dd903ab654b01925fa55a 206 Gene3D G3DSA:3.40.50.880 1 206 1.1E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS02105 fcbb8b2f0d7dd903ab654b01925fa55a 206 SUPERFAMILY SSF52317 1 187 7.8E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 SMART SM00710 418 440 2100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 SMART SM00710 295 319 5000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 SMART SM00710 448 474 6700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 SMART SM00710 320 341 540.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 SMART SM00710 354 375 19.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 Pfam PF12708 Pectate lyase superfamily protein 108 169 6.8E-9 T 28-03-2018 IPR024535 Pectate lyase superfamily protein SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 Gene3D G3DSA:2.160.20.10 86 520 5.0E-88 T 28-03-2018 IPR012334 Pectin lyase fold SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 SUPERFAMILY SSF51126 97 489 1.01E-81 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor SMD44_RS30805 1c0ecdb692d3857243a7835ca4fe4fe3 520 Pfam PF00295 Glycosyl hydrolases family 28 263 467 5.2E-12 T 28-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 SMD44_RS43825 9aa418eacef0e2f6f0eaad943d827516 260 SUPERFAMILY SSF48576 9 236 8.78E-30 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS43825 9aa418eacef0e2f6f0eaad943d827516 260 Pfam PF00494 Squalene/phytoene synthase 24 243 1.2E-14 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMD44_RS43825 9aa418eacef0e2f6f0eaad943d827516 260 Gene3D G3DSA:1.10.600.10 3 245 5.3E-32 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS12940 c0aacfb9ff46597b98543ac7b32fe911 268 SUPERFAMILY SSF56112 18 220 1.95E-14 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS12940 c0aacfb9ff46597b98543ac7b32fe911 268 Gene3D G3DSA:3.90.1200.10 98 239 4.1E-9 T 28-03-2018 SMD44_RS24135 57f75f5ddb233a8da171423e9c2ff18e 95 Pfam PF05768 Glutaredoxin-like domain (DUF836) 21 93 8.8E-19 T 28-03-2018 IPR008554 Glutaredoxin-like SMD44_RS24135 57f75f5ddb233a8da171423e9c2ff18e 95 Gene3D G3DSA:3.40.30.10 19 94 1.4E-8 T 28-03-2018 SMD44_RS24135 57f75f5ddb233a8da171423e9c2ff18e 95 SUPERFAMILY SSF52833 15 93 3.52E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS39745 1421a1c34735b4d4a8e4137d650252c2 332 SUPERFAMILY SSF52777 172 317 1.11E-23 T 28-03-2018 SMD44_RS39745 1421a1c34735b4d4a8e4137d650252c2 332 Pfam PF00668 Condensation domain 14 315 1.5E-41 T 28-03-2018 IPR001242 Condensation domain SMD44_RS39745 1421a1c34735b4d4a8e4137d650252c2 332 SUPERFAMILY SSF52777 8 164 6.11E-26 T 28-03-2018 SMD44_RS39745 1421a1c34735b4d4a8e4137d650252c2 332 Gene3D G3DSA:3.30.559.10 3 180 6.4E-20 T 28-03-2018 SMD44_RS18885 eed7958522594d79f4b6d5d055d5bc87 174 Pfam PF00583 Acetyltransferase (GNAT) family 54 152 7.2E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS18885 eed7958522594d79f4b6d5d055d5bc87 174 Gene3D G3DSA:3.40.630.30 23 174 4.0E-21 T 28-03-2018 SMD44_RS18885 eed7958522594d79f4b6d5d055d5bc87 174 SUPERFAMILY SSF55729 25 172 2.3E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS16505 20a720ec86fc5ea4fe11ed442df7194b 454 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 204 365 1.2E-38 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS16505 20a720ec86fc5ea4fe11ed442df7194b 454 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 204 365 8.7E-44 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS13450 94ba2f8d94541fb7a4d4abcec0c1e2ad 403 Pfam PF13416 Bacterial extracellular solute-binding protein 38 334 1.4E-31 T 28-03-2018 SMD44_RS13450 94ba2f8d94541fb7a4d4abcec0c1e2ad 403 Gene3D G3DSA:3.40.190.10 126 401 1.2E-41 T 28-03-2018 SMD44_RS13450 94ba2f8d94541fb7a4d4abcec0c1e2ad 403 SUPERFAMILY SSF53850 3 395 7.61E-62 T 28-03-2018 SMD44_RS04405 d4625c7941b600b7863446b96a1e01b6 305 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 10 302 8.4E-23 T 28-03-2018 IPR024455 Phage capsid SMD44_RS04405 d4625c7941b600b7863446b96a1e01b6 305 Pfam PF05065 Phage capsid family 10 303 5.0E-18 T 28-03-2018 IPR024455 Phage capsid SMD44_RS04405 d4625c7941b600b7863446b96a1e01b6 305 Gene3D G3DSA:3.30.2400.10 27 201 2.8E-10 T 28-03-2018 SMD44_RS04405 d4625c7941b600b7863446b96a1e01b6 305 SUPERFAMILY SSF56563 7 303 1.7E-26 T 28-03-2018 SMD44_RS24650 41ef51e5887f5592b88752059aaf1bda 210 Gene3D G3DSA:3.40.50.300 1 196 4.8E-19 T 28-03-2018 SMD44_RS24650 41ef51e5887f5592b88752059aaf1bda 210 SUPERFAMILY SSF52540 1 121 3.46E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS37185 d4475c586588c3f4eea867ed9144df55 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 64 336 1.9E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS37185 d4475c586588c3f4eea867ed9144df55 348 Gene3D G3DSA:1.10.3470.10 50 341 4.0E-32 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 94 253 4.0E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 78 265 1.3E-108 T 28-03-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 Pfam PF04542 Sigma-70 region 2 95 158 7.6E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 113 144 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 Pfam PF08281 Sigma-70, region 4 200 250 2.3E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 Gene3D G3DSA:1.10.10.10 156 257 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 SUPERFAMILY SSF88946 84 173 4.97E-24 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 SUPERFAMILY SSF88659 193 255 7.66E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS28265 4724f6031b49b91f87c3063fa79fd6f9 279 Gene3D G3DSA:1.10.1740.10 75 155 6.4E-23 T 28-03-2018 SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 Pfam PF00571 CBS domain 106 148 1.8E-4 T 28-03-2018 IPR000644 CBS domain SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 Pfam PF00571 CBS domain 158 210 7.3E-6 T 28-03-2018 IPR000644 CBS domain SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 9 484 1.4E-278 T 28-03-2018 IPR005991 IMP dehydrogenase-related 1 SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 SUPERFAMILY SSF54631 103 211 3.54E-20 T 28-03-2018 SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 SUPERFAMILY SSF51412 210 481 1.96E-89 T 28-03-2018 SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 SUPERFAMILY SSF51412 18 100 1.96E-89 T 28-03-2018 SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 Gene3D G3DSA:3.20.20.70 3 477 1.2E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 PIRSF PIRSF000130 8 487 5.6E-146 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 20 481 5.0E-102 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 SMART SM00116 164 212 0.18 T 28-03-2018 IPR000644 CBS domain SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 SMART SM00116 105 153 1.8 T 28-03-2018 IPR000644 CBS domain SMD44_RS07150 1c20f12bb86564c09c8be54f28960f01 487 SMART SM01240 18 482 3.3E-193 T 28-03-2018 SMD44_RS16310 e225e5a719fc7a00b44677a3638bd639 441 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 281 357 1.0E-7 T 28-03-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain SMD44_RS34635 e0b00c05bee6523c9fb997790a6b572c 141 SUPERFAMILY SSF46785 9 138 3.59E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34635 e0b00c05bee6523c9fb997790a6b572c 141 Gene3D G3DSA:1.10.10.10 2 139 8.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34635 e0b00c05bee6523c9fb997790a6b572c 141 Pfam PF12802 MarR family 32 89 8.5E-10 T 28-03-2018 SMD44_RS34635 e0b00c05bee6523c9fb997790a6b572c 141 SMART SM00347 26 126 2.9E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS34635 e0b00c05bee6523c9fb997790a6b572c 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 4.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS34635 e0b00c05bee6523c9fb997790a6b572c 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 4.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS34635 e0b00c05bee6523c9fb997790a6b572c 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 4.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS34635 e0b00c05bee6523c9fb997790a6b572c 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 4.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS02890 d4d04267327764188a7662c03b89374d 734 Gene3D G3DSA:3.40.50.300 603 734 1.0E-7 T 28-03-2018 SMD44_RS02890 d4d04267327764188a7662c03b89374d 734 SUPERFAMILY SSF52540 510 733 1.48E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS02890 d4d04267327764188a7662c03b89374d 734 SUPERFAMILY SSF52540 188 270 1.48E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS02890 d4d04267327764188a7662c03b89374d 734 Gene3D G3DSA:3.40.50.300 194 592 2.5E-30 T 28-03-2018 SMD44_RS20155 af127995ba638f2fa62f134d81cda5b9 339 SUPERFAMILY SSF103481 34 142 1.7E-11 T 28-03-2018 SMD44_RS20155 af127995ba638f2fa62f134d81cda5b9 339 Pfam PF00892 EamA-like transporter family 150 285 8.0E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS20155 af127995ba638f2fa62f134d81cda5b9 339 Pfam PF00892 EamA-like transporter family 4 139 1.6E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS20155 af127995ba638f2fa62f134d81cda5b9 339 SUPERFAMILY SSF103481 191 290 5.89E-10 T 28-03-2018 SMD44_RS06235 6e17b1bfa023c337b4519afa0dfcdd39 259 SMART SM00563 70 183 7.9E-26 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS06235 6e17b1bfa023c337b4519afa0dfcdd39 259 Gene3D G3DSA:3.40.1130.10 64 241 9.2E-23 T 28-03-2018 SMD44_RS06235 6e17b1bfa023c337b4519afa0dfcdd39 259 SUPERFAMILY SSF69593 66 183 2.88E-22 T 28-03-2018 SMD44_RS06235 6e17b1bfa023c337b4519afa0dfcdd39 259 Pfam PF01553 Acyltransferase 67 180 7.2E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS03265 82371683f7d79190fe9c380031178d4f 149 SUPERFAMILY SSF54427 4 144 5.54E-22 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS03265 82371683f7d79190fe9c380031178d4f 149 Pfam PF12680 SnoaL-like domain 19 138 7.1E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS03265 82371683f7d79190fe9c380031178d4f 149 Gene3D G3DSA:3.10.450.50 2 146 2.1E-19 T 28-03-2018 SMD44_RS10935 73043b9afa6598340a640e0b0358c481 550 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS10935 73043b9afa6598340a640e0b0358c481 550 SMART SM00220 12 276 9.5E-66 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS10935 73043b9afa6598340a640e0b0358c481 550 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS10935 73043b9afa6598340a640e0b0358c481 550 Gene3D G3DSA:3.30.200.20 1 98 4.6E-25 T 28-03-2018 SMD44_RS10935 73043b9afa6598340a640e0b0358c481 550 SUPERFAMILY SSF56112 6 324 2.7E-68 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS10935 73043b9afa6598340a640e0b0358c481 550 Pfam PF00069 Protein kinase domain 12 238 9.5E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS10935 73043b9afa6598340a640e0b0358c481 550 Gene3D G3DSA:1.10.510.10 99 367 2.9E-44 T 28-03-2018 SMD44_RS00440 656f79a102b171bdbfbc92c96a6b7427 131 Pfam PF03995 Peptidase inhibitor family I36 50 103 4.4E-5 T 28-03-2018 SMD44_RS00440 656f79a102b171bdbfbc92c96a6b7427 131 Gene3D G3DSA:2.60.20.10 28 131 7.9E-5 T 28-03-2018 SMD44_RS33620 38f4860ac98a6e47489018844da9df7d 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 335 8.3E-52 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS33620 38f4860ac98a6e47489018844da9df7d 350 Gene3D G3DSA:1.10.3470.10 46 341 4.0E-19 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS40490 73affd54e2b359e4d5d70a2a1562d1f4 324 Pfam PF00296 Luciferase-like monooxygenase 22 295 5.9E-24 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS40490 73affd54e2b359e4d5d70a2a1562d1f4 324 SUPERFAMILY SSF51679 5 321 2.22E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS40490 73affd54e2b359e4d5d70a2a1562d1f4 324 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 6 318 6.7E-95 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 SMD44_RS40490 73affd54e2b359e4d5d70a2a1562d1f4 324 Gene3D G3DSA:3.20.20.30 9 323 5.0E-57 T 28-03-2018 SMD44_RS17165 8be28ce6fa81490105d87a4d813b6bb5 131 Gene3D G3DSA:3.30.565.10 1 130 2.3E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17165 8be28ce6fa81490105d87a4d813b6bb5 131 SUPERFAMILY SSF55874 18 124 4.61E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS17165 8be28ce6fa81490105d87a4d813b6bb5 131 Pfam PF13581 Histidine kinase-like ATPase domain 8 110 2.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS06420 d65e4a2a33e6163856b2d35ac3687911 552 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 33 513 16.35 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMD44_RS06420 d65e4a2a33e6163856b2d35ac3687911 552 Pfam PF00795 Carbon-nitrogen hydrolase 242 496 1.1E-21 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS06420 d65e4a2a33e6163856b2d35ac3687911 552 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 88 474 3.3E-89 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMD44_RS06420 d65e4a2a33e6163856b2d35ac3687911 552 Gene3D G3DSA:3.60.110.10 232 496 7.8E-41 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS06420 d65e4a2a33e6163856b2d35ac3687911 552 SUPERFAMILY SSF56317 237 508 2.88E-41 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS11205 b975d50217bea95863888bc893a45f9a 323 SUPERFAMILY SSF55961 7 137 6.42E-9 T 28-03-2018 SMD44_RS11205 b975d50217bea95863888bc893a45f9a 323 Gene3D G3DSA:3.30.530.20 4 147 1.0E-12 T 28-03-2018 IPR023393 START-like domain SMD44_RS43095 34892b8eed81df5ff1db8a6e42b8ed46 287 Gene3D G3DSA:3.40.50.300 1 269 1.4E-15 T 28-03-2018 SMD44_RS43095 34892b8eed81df5ff1db8a6e42b8ed46 287 SUPERFAMILY SSF52540 1 229 1.72E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS23620 a8319dc95878a3c2defc592cd25d62e7 169 SUPERFAMILY SSF55874 57 151 1.87E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23620 a8319dc95878a3c2defc592cd25d62e7 169 Pfam PF13581 Histidine kinase-like ATPase domain 33 147 9.0E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23620 a8319dc95878a3c2defc592cd25d62e7 169 Gene3D G3DSA:3.30.565.10 23 169 1.5E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28145 979643d6b928f0a2d56821566492cf25 226 SUPERFAMILY SSF51219 17 217 2.88E-48 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD44_RS28145 979643d6b928f0a2d56821566492cf25 226 Gene3D G3DSA:3.60.160.10 12 226 4.7E-45 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS28145 979643d6b928f0a2d56821566492cf25 226 Pfam PF01987 Mitochondrial biogenesis AIM24 19 214 1.0E-34 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS21215 92013021e294cfc31a8632bfc55e2776 133 Gene3D G3DSA:3.10.180.10 2 133 3.1E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS21215 92013021e294cfc31a8632bfc55e2776 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 120 9.1E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS21215 92013021e294cfc31a8632bfc55e2776 133 SUPERFAMILY SSF54593 7 123 1.32E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS28480 5eda51c23d7f3ffb526c0e0a6542e72e 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 133 212 4.4E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS28480 5eda51c23d7f3ffb526c0e0a6542e72e 227 SUPERFAMILY SSF56784 28 222 1.41E-27 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS28480 5eda51c23d7f3ffb526c0e0a6542e72e 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 128 208 1.7E-8 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS28480 5eda51c23d7f3ffb526c0e0a6542e72e 227 Gene3D G3DSA:3.40.50.1000 17 226 5.6E-20 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS28480 5eda51c23d7f3ffb526c0e0a6542e72e 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 194 2.0E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS28480 5eda51c23d7f3ffb526c0e0a6542e72e 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 27 38 2.0E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS28480 5eda51c23d7f3ffb526c0e0a6542e72e 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 126 139 2.0E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS28480 5eda51c23d7f3ffb526c0e0a6542e72e 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 172 2.0E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS35220 84d1ae62a836e09b9fc4925a0a334650 339 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 16 261 1.7E-72 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain SMD44_RS35220 84d1ae62a836e09b9fc4925a0a334650 339 Pfam PF01896 DNA primase small subunit 137 257 7.1E-7 T 28-03-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 SMD44_RS33185 30cba204f5085dcaf787acb9707f6e07 459 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 2.2E-5 T 28-03-2018 SMD44_RS33185 30cba204f5085dcaf787acb9707f6e07 459 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 336 2.2E-5 T 28-03-2018 SMD44_RS33185 30cba204f5085dcaf787acb9707f6e07 459 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 2.2E-5 T 28-03-2018 SMD44_RS33185 30cba204f5085dcaf787acb9707f6e07 459 SUPERFAMILY SSF51905 16 207 1.21E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS33185 30cba204f5085dcaf787acb9707f6e07 459 SUPERFAMILY SSF51905 312 376 1.21E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS33185 30cba204f5085dcaf787acb9707f6e07 459 Gene3D G3DSA:3.50.50.60 15 357 2.8E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 213 347 1.1E-37 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 Gene3D G3DSA:3.30.43.10 1 71 2.0E-24 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 SUPERFAMILY SSF56194 213 349 1.83E-33 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 SUPERFAMILY SSF56176 8 183 7.48E-35 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 343 6.3E-47 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 75.447 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 Gene3D G3DSA:3.90.78.10 229 347 1.2E-40 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 Gene3D G3DSA:3.30.465.10 72 224 8.7E-45 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS25385 c667283ebd3b00dfbe8e1cc6a7c322ed 351 Pfam PF01565 FAD binding domain 22 140 2.7E-20 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD44_RS14515 2ca712f9a54f02759337592ade3d2b56 712 Gene3D G3DSA:2.60.200.20 351 711 1.0E-28 T 28-03-2018 SMD44_RS14515 2ca712f9a54f02759337592ade3d2b56 712 SMART SM00240 624 683 6.4E-5 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS14515 2ca712f9a54f02759337592ade3d2b56 712 Pfam PF00498 FHA domain 625 702 6.9E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD44_RS14515 2ca712f9a54f02759337592ade3d2b56 712 SUPERFAMILY SSF49879 556 707 1.53E-21 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS12850 bd7d2dfdf17d915090ceca5af3cde805 420 Pfam PF13556 PucR C-terminal helix-turn-helix domain 352 410 4.4E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS12850 bd7d2dfdf17d915090ceca5af3cde805 420 Gene3D G3DSA:1.10.10.10 322 417 2.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS36565 b733780e88ada9d4264e1870122a1f19 286 Gene3D G3DSA:3.40.50.1820 44 279 3.5E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36565 b733780e88ada9d4264e1870122a1f19 286 SUPERFAMILY SSF53474 23 184 5.08E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS36565 b733780e88ada9d4264e1870122a1f19 286 SMART SM00824 Thioesterase 54 235 1.7E-20 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD44_RS36565 b733780e88ada9d4264e1870122a1f19 286 Pfam PF00975 Thioesterase domain 52 157 1.9E-18 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD44_RS04095 af24cb78f42b4e2be801d28d62228a77 655 Gene3D G3DSA:1.10.260.40 1 62 6.3E-5 T 28-03-2018 SMD44_RS04095 af24cb78f42b4e2be801d28d62228a77 655 Gene3D G3DSA:3.40.50.300 128 388 2.5E-6 T 28-03-2018 SMD44_RS04095 af24cb78f42b4e2be801d28d62228a77 655 Gene3D G3DSA:3.40.50.300 68 127 0.0011 T 28-03-2018 SMD44_RS04095 af24cb78f42b4e2be801d28d62228a77 655 SMART SM00530 7 63 0.0029 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS04095 af24cb78f42b4e2be801d28d62228a77 655 SUPERFAMILY SSF52540 98 303 5.7E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS11570 c1c356ce16a233c2454b23ba606c3d25 373 SUPERFAMILY SSF81606 159 366 4.71E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS11570 c1c356ce16a233c2454b23ba606c3d25 373 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 173 365 5.9E-44 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS11570 c1c356ce16a233c2454b23ba606c3d25 373 SMART SM00331 145 367 3.1E-27 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS11570 c1c356ce16a233c2454b23ba606c3d25 373 Gene3D G3DSA:3.60.40.10 112 368 1.8E-30 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS37855 5705ec4f0b3780741d36b11ae7e48322 108 Gene3D G3DSA:1.10.720.10 77 107 3.1E-7 T 28-03-2018 SMD44_RS14790 68776cd90e2c44af2d5626975cd2825d 131 SUPERFAMILY SSF102546 2 131 1.31E-38 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SMD44_RS14790 68776cd90e2c44af2d5626975cd2825d 131 Pfam PF05025 RbsD / FucU transport protein family 3 129 1.6E-38 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SMD44_RS14790 68776cd90e2c44af2d5626975cd2825d 131 Gene3D G3DSA:3.40.1650.10 8 128 1.8E-31 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SMD44_RS14790 68776cd90e2c44af2d5626975cd2825d 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 29.019 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 SMD44_RS03730 400fb20f55ca14814bdef9163063ec60 390 Gene3D G3DSA:3.50.50.60 3 341 3.5E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03730 400fb20f55ca14814bdef9163063ec60 390 Pfam PF01494 FAD binding domain 5 321 7.8E-19 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS03730 400fb20f55ca14814bdef9163063ec60 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.9E-13 T 28-03-2018 SMD44_RS03730 400fb20f55ca14814bdef9163063ec60 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 3.9E-13 T 28-03-2018 SMD44_RS03730 400fb20f55ca14814bdef9163063ec60 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 3.9E-13 T 28-03-2018 SMD44_RS03730 400fb20f55ca14814bdef9163063ec60 390 SUPERFAMILY SSF51905 265 367 6.26E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03730 400fb20f55ca14814bdef9163063ec60 390 SUPERFAMILY SSF51905 4 166 6.26E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS07530 63163708671738c9ac192bdb0199efd1 188 Pfam PF14280 Domain of unknown function (DUF4365) 34 181 5.6E-25 T 28-03-2018 IPR025375 Domain of unknown function DUF4365 SMD44_RS14950 ad8d97e5f2d5f070acd71b5e6710dc79 538 Pfam PF01039 Carboxyl transferase domain 51 522 8.7E-152 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMD44_RS14950 ad8d97e5f2d5f070acd71b5e6710dc79 538 SUPERFAMILY SSF52096 240 520 1.06E-87 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS14950 ad8d97e5f2d5f070acd71b5e6710dc79 538 Gene3D G3DSA:3.90.226.10 13 275 3.9E-66 T 28-03-2018 SMD44_RS14950 ad8d97e5f2d5f070acd71b5e6710dc79 538 SUPERFAMILY SSF52096 29 272 4.98E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS14950 ad8d97e5f2d5f070acd71b5e6710dc79 538 Gene3D G3DSA:3.90.226.10 276 531 1.1E-71 T 28-03-2018 SMD44_RS19620 42df5c249303556219589eef12644f37 421 Gene3D G3DSA:1.20.1250.20 205 409 3.2E-14 T 28-03-2018 SMD44_RS19620 42df5c249303556219589eef12644f37 421 SUPERFAMILY SSF103473 15 401 5.23E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS19620 42df5c249303556219589eef12644f37 421 Pfam PF07690 Major Facilitator Superfamily 18 365 1.5E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS19620 42df5c249303556219589eef12644f37 421 Gene3D G3DSA:1.20.1250.20 3 202 8.8E-27 T 28-03-2018 SMD44_RS35935 e4deafa6de43a01e26855b5490d8d6bd 123 Pfam PF05331 Protein of unknown function (DUF742) 13 122 1.3E-34 T 28-03-2018 IPR007995 Protein of unknown function DUF742 SMD44_RS35935 e4deafa6de43a01e26855b5490d8d6bd 123 Gene3D G3DSA:1.10.10.10 52 119 7.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20875 77ee9652e9aace27261d79c3f3588137 105 Pfam PF07883 Cupin domain 33 100 9.0E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS20875 77ee9652e9aace27261d79c3f3588137 105 Gene3D G3DSA:2.60.120.10 2 105 2.1E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS20875 77ee9652e9aace27261d79c3f3588137 105 SUPERFAMILY SSF51182 17 103 1.72E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS30155 d54aa124e2d09a791b918c404872420a 194 Pfam PF03029 Conserved hypothetical ATP binding protein 22 189 6.2E-28 T 28-03-2018 IPR004130 GPN-loop GTPase SMD44_RS30155 d54aa124e2d09a791b918c404872420a 194 Gene3D G3DSA:3.40.50.300 8 192 6.1E-19 T 28-03-2018 SMD44_RS30155 d54aa124e2d09a791b918c404872420a 194 SUPERFAMILY SSF52540 17 191 3.32E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS26275 195076be9c97cc6172730169abb25e9d 289 SUPERFAMILY SSF88713 5 286 2.89E-56 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS26275 195076be9c97cc6172730169abb25e9d 289 Gene3D G3DSA:3.20.20.370 5 288 2.9E-42 T 28-03-2018 SMD44_RS26275 195076be9c97cc6172730169abb25e9d 289 Pfam PF01522 Polysaccharide deacetylase 64 175 1.8E-9 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PIRSF PIRSF000126 1 252 3.2E-62 T 28-03-2018 SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 SUPERFAMILY SSF51735 3 239 4.83E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 Pfam PF00106 short chain dehydrogenase 3 188 1.0E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS25780 f78ca15a4b5b0e353b9ce124ef931faf 257 Gene3D G3DSA:3.40.50.720 2 242 6.1E-48 T 28-03-2018 SMD44_RS01195 532dd5e6210f7376b13feb58cf657b6e 293 SUPERFAMILY SSF52038 163 250 2.75E-14 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SMD44_RS01195 532dd5e6210f7376b13feb58cf657b6e 293 Pfam PF01337 Barstar (barnase inhibitor) 166 252 3.1E-16 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SMD44_RS01195 532dd5e6210f7376b13feb58cf657b6e 293 Gene3D G3DSA:3.30.370.10 161 257 2.0E-17 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SMD44_RS27425 1db185862da75e414f24369d92314d51 440 Pfam PF02562 PhoH-like protein 230 435 1.3E-53 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 SMD44_RS27425 1db185862da75e414f24369d92314d51 440 Gene3D G3DSA:3.40.50.1010 11 185 8.0E-27 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS27425 1db185862da75e414f24369d92314d51 440 Gene3D G3DSA:3.40.50.300 227 433 1.4E-16 T 28-03-2018 SMD44_RS27425 1db185862da75e414f24369d92314d51 440 SMART SM00670 12 139 1.7E-12 T 28-03-2018 IPR002716 PIN domain SMD44_RS27425 1db185862da75e414f24369d92314d51 440 Pfam PF13638 PIN domain 14 152 2.4E-26 T 28-03-2018 IPR002716 PIN domain SMD44_RS27425 1db185862da75e414f24369d92314d51 440 SUPERFAMILY SSF88723 104 150 1.88E-8 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS27425 1db185862da75e414f24369d92314d51 440 SUPERFAMILY SSF88723 13 71 1.88E-8 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS27425 1db185862da75e414f24369d92314d51 440 SUPERFAMILY SSF52540 229 410 7.85E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS17115 a1ab98f02d2e2c35d8965c2b3bb00d32 282 SUPERFAMILY SSF103481 181 280 7.45E-10 T 28-03-2018 SMD44_RS17115 a1ab98f02d2e2c35d8965c2b3bb00d32 282 Pfam PF00892 EamA-like transporter family 149 280 4.8E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS17115 a1ab98f02d2e2c35d8965c2b3bb00d32 282 SUPERFAMILY SSF103481 42 134 1.12E-10 T 28-03-2018 SMD44_RS03815 9616f24d0f32d0a8ff4becb9c35c87c3 236 Gene3D G3DSA:1.10.10.60 42 76 4.2E-9 T 28-03-2018 SMD44_RS03815 9616f24d0f32d0a8ff4becb9c35c87c3 236 Gene3D G3DSA:1.10.10.60 4 41 1.9E-12 T 28-03-2018 SMD44_RS03815 9616f24d0f32d0a8ff4becb9c35c87c3 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 50 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS03815 9616f24d0f32d0a8ff4becb9c35c87c3 236 SUPERFAMILY SSF46689 4 80 3.59E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS26455 a3ba4b84e4ae86d277c921311f884f6c 328 Pfam PF01040 UbiA prenyltransferase family 57 260 7.1E-15 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMD44_RS09615 b7aef722b1e2038705d571462b5e0aa7 1216 Pfam PF02514 CobN/Magnesium Chelatase 101 1195 0.0 T 28-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 SMD44_RS09615 b7aef722b1e2038705d571462b5e0aa7 1216 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 38 1206 0.0 T 28-03-2018 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 SMD44_RS09615 b7aef722b1e2038705d571462b5e0aa7 1216 Gene3D G3DSA:3.40.50.2300 9 112 9.8E-4 T 28-03-2018 SMD44_RS13180 a3a43c370abff8100ef406bb1a4c7391 57 Pfam PF02416 mttA/Hcf106 family 3 47 8.1E-7 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 4.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 4.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 4.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 Pfam PF00106 short chain dehydrogenase 9 211 3.3E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 Gene3D G3DSA:3.40.50.720 2 301 3.2E-62 T 28-03-2018 SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 234 8.5E-4 T 28-03-2018 SMD44_RS12260 03f33ae9fcf77fbbb28d23cc198bed85 313 SUPERFAMILY SSF51735 2 265 1.88E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 Gene3D G3DSA:1.20.1250.20 22 209 1.9E-32 T 28-03-2018 SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 Gene3D G3DSA:1.20.1250.20 262 505 1.3E-26 T 28-03-2018 SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 Pfam PF07690 Major Facilitator Superfamily 29 420 2.0E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 87 109 6.4E-8 T 28-03-2018 SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 174 198 6.4E-8 T 28-03-2018 SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 6.4E-8 T 28-03-2018 SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 6.4E-8 T 28-03-2018 SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 SUPERFAMILY SSF103473 472 500 2.49E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 SUPERFAMILY SSF103473 258 430 2.49E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 SUPERFAMILY SSF103473 15 208 2.49E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS31475 683a74205c85f6f0c8982c7e63a51da7 518 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 28 456 1.1E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS13460 ac8c33268ff3f8a67f34408611e166bd 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 271 1.9E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS13460 ac8c33268ff3f8a67f34408611e166bd 278 Gene3D G3DSA:1.10.3720.10 5 265 6.1E-39 T 28-03-2018 SMD44_RS13460 ac8c33268ff3f8a67f34408611e166bd 278 SUPERFAMILY SSF161098 8 275 1.59E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS06500 a8d497a044a6c890380258ceb7079e4d 300 SUPERFAMILY SSF53850 90 293 6.88E-34 T 28-03-2018 SMD44_RS06500 a8d497a044a6c890380258ceb7079e4d 300 SUPERFAMILY SSF46785 1 112 1.09E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06500 a8d497a044a6c890380258ceb7079e4d 300 Gene3D G3DSA:1.10.10.10 1 84 5.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06500 a8d497a044a6c890380258ceb7079e4d 300 Pfam PF03466 LysR substrate binding domain 88 293 1.5E-38 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS06500 a8d497a044a6c890380258ceb7079e4d 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.0E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS06500 a8d497a044a6c890380258ceb7079e4d 300 Gene3D G3DSA:3.40.190.10 183 271 2.4E-22 T 28-03-2018 SMD44_RS06500 a8d497a044a6c890380258ceb7079e4d 300 Gene3D G3DSA:3.40.190.10 88 182 1.6E-20 T 28-03-2018 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 SUPERFAMILY SSF52172 1 113 4.84E-28 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 Gene3D G3DSA:1.10.10.10 122 216 6.7E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 SMART SM00421 149 206 1.0E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 SUPERFAMILY SSF46894 140 211 1.36E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.2E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 SMART SM00448 1 110 7.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 Gene3D G3DSA:3.40.50.2300 1 121 2.1E-28 T 28-03-2018 SMD44_RS11230 85e0da183611d4777c705fcc357cbde2 219 Pfam PF00072 Response regulator receiver domain 1 110 2.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS34270 fdbc94081b8922ec958cbc19ded2f527 192 SUPERFAMILY SSF46689 4 74 1.69E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS34270 fdbc94081b8922ec958cbc19ded2f527 192 Gene3D G3DSA:1.10.357.10 2 187 1.2E-28 T 28-03-2018 SMD44_RS34270 fdbc94081b8922ec958cbc19ded2f527 192 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 78 188 1.3E-14 T 28-03-2018 SMD44_RS34270 fdbc94081b8922ec958cbc19ded2f527 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 52 1.0E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS34270 fdbc94081b8922ec958cbc19ded2f527 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS34270 fdbc94081b8922ec958cbc19ded2f527 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS34270 fdbc94081b8922ec958cbc19ded2f527 192 SUPERFAMILY SSF48498 78 186 6.67E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS09075 3fd7ab4e2a8b8a8e41c64289c6f53378 172 Pfam PF00355 Rieske [2Fe-2S] domain 81 158 8.2E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS09075 3fd7ab4e2a8b8a8e41c64289c6f53378 172 PRINTS PR00162 Rieske 2Fe-2S subunit signature 132 144 7.2E-9 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS09075 3fd7ab4e2a8b8a8e41c64289c6f53378 172 PRINTS PR00162 Rieske 2Fe-2S subunit signature 112 123 7.2E-9 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS09075 3fd7ab4e2a8b8a8e41c64289c6f53378 172 PRINTS PR00162 Rieske 2Fe-2S subunit signature 145 157 7.2E-9 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD44_RS09075 3fd7ab4e2a8b8a8e41c64289c6f53378 172 Gene3D G3DSA:2.102.10.10 15 171 2.7E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS09075 3fd7ab4e2a8b8a8e41c64289c6f53378 172 SUPERFAMILY SSF50022 80 171 1.27E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD44_RS30185 1439f3276a2e9f33d2d959e8e8b3dcce 137 Gene3D G3DSA:3.30.450.30 4 131 1.4E-44 T 28-03-2018 SMD44_RS30185 1439f3276a2e9f33d2d959e8e8b3dcce 137 SUPERFAMILY SSF103196 2 125 7.59E-32 T 28-03-2018 SMD44_RS30185 1439f3276a2e9f33d2d959e8e8b3dcce 137 SMART SM00960 9 99 1.8E-33 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS30185 1439f3276a2e9f33d2d959e8e8b3dcce 137 Pfam PF03259 Roadblock/LC7 domain 9 99 4.6E-26 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS18190 22e62a2ae1eb4da24799417cecd203c1 275 Gene3D G3DSA:1.10.260.40 15 128 3.7E-8 T 28-03-2018 SMD44_RS18190 22e62a2ae1eb4da24799417cecd203c1 275 SUPERFAMILY SSF47413 19 72 3.44E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS25260 88b263e11488cfb112e07ddc5f994f09 133 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 34 132 1.2E-29 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS17770 0272fb0f4faf0feed41e0c2a83d6c2bb 124 Gene3D G3DSA:3.40.1800.10 24 120 2.9E-5 T 28-03-2018 SMD44_RS03365 2607c368cf2e5b8123aae4a817e6eb89 316 Gene3D G3DSA:3.10.25.10 205 313 9.1E-22 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS03365 2607c368cf2e5b8123aae4a817e6eb89 316 Gene3D G3DSA:3.40.50.170 1 204 4.9E-52 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS03365 2607c368cf2e5b8123aae4a817e6eb89 316 SUPERFAMILY SSF53328 1 203 5.76E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS03365 2607c368cf2e5b8123aae4a817e6eb89 316 Pfam PF02911 Formyl transferase, C-terminal domain 206 305 8.7E-16 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS03365 2607c368cf2e5b8123aae4a817e6eb89 316 Pfam PF00551 Formyl transferase 1 165 5.8E-29 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD44_RS03365 2607c368cf2e5b8123aae4a817e6eb89 316 SUPERFAMILY SSF50486 206 307 8.16E-18 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMD44_RS20185 28bb72ad7a59627a415bfccfb23b6369 98 PIRSF PIRSF006909 1 98 5.5E-58 T 28-03-2018 IPR014447 Uncharacterised conserved protein UCP006909 SMD44_RS35080 bd5f92726661e31584686705d016cac0 284 Gene3D G3DSA:1.20.144.10 9 259 2.6E-4 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS35080 bd5f92726661e31584686705d016cac0 284 Pfam PF14378 PAP2 superfamily 62 241 5.4E-41 T 28-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD44_RS07155 e3d6d9afacacf46a7d1bdce1b9f63746 137 Gene3D G3DSA:3.30.370.10 34 127 2.4E-27 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SMD44_RS07155 e3d6d9afacacf46a7d1bdce1b9f63746 137 SUPERFAMILY SSF52038 36 123 4.05E-22 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SMD44_RS07155 e3d6d9afacacf46a7d1bdce1b9f63746 137 Pfam PF01337 Barstar (barnase inhibitor) 39 121 2.7E-26 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) SMD44_RS12665 de5eb2f5330c95a9a2972bf1f51c9904 388 PIRSF PIRSF015582 14 381 3.0E-80 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like SMD44_RS12665 de5eb2f5330c95a9a2972bf1f51c9904 388 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 371 5.4E-127 T 28-03-2018 SMD44_RS12665 de5eb2f5330c95a9a2972bf1f51c9904 388 Gene3D G3DSA:3.20.20.360 21 338 2.5E-41 T 28-03-2018 SMD44_RS12665 de5eb2f5330c95a9a2972bf1f51c9904 388 SUPERFAMILY SSF51621 35 251 1.73E-24 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS12665 de5eb2f5330c95a9a2972bf1f51c9904 388 SUPERFAMILY SSF51621 282 315 1.73E-24 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS16475 f81d19b5feccc8e9175ff534c50e9992 602 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 203 365 1.3E-42 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS16475 f81d19b5feccc8e9175ff534c50e9992 602 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 203 365 4.6E-37 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS16475 f81d19b5feccc8e9175ff534c50e9992 602 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 480 573 5.1E-12 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD44_RS10925 18aa92ef9f10c15f1b0dee9474904d9e 272 Pfam PF13462 Thioredoxin 82 267 7.2E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS10925 18aa92ef9f10c15f1b0dee9474904d9e 272 SUPERFAMILY SSF52833 80 250 3.89E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS10925 18aa92ef9f10c15f1b0dee9474904d9e 272 Gene3D G3DSA:3.40.30.10 82 272 1.6E-31 T 28-03-2018 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 SUPERFAMILY SSF111326 4 549 7.72E-247 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 ProSitePatterns PS01233 Urocanase signature. 436 451 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 Pfam PF01175 Urocanase Rossmann-like domain 136 343 8.1E-83 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 Gene3D G3DSA:3.40.1770.10 5 148 4.7E-28 T 28-03-2018 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 Gene3D G3DSA:3.40.1770.10 191 548 1.0E-153 T 28-03-2018 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 PIRSF PIRSF001423 1 552 2.5E-278 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 Pfam PF17392 Urocanase C-terminal domain 346 540 3.2E-92 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 1.4E-273 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 Pfam PF17391 Urocanase N-terminal domain 7 133 4.1E-60 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS16630 2206f989b167942f54c0009d7ca718d7 552 Hamap MF_00577 Urocanate hydratase [hutU]. 2 550 49.12 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD44_RS12540 fe119b6fa244e7c72af5e284a06148b9 153 Pfam PF07681 DoxX 15 92 1.2E-8 T 28-03-2018 IPR032808 DoxX family SMD44_RS10755 665dbc8f9c8658a2a3350b41b5c56396 332 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 255 5.7E-65 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMD44_RS10755 665dbc8f9c8658a2a3350b41b5c56396 332 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMD44_RS10755 665dbc8f9c8658a2a3350b41b5c56396 332 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 11 257 8.9E-40 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMD44_RS10755 665dbc8f9c8658a2a3350b41b5c56396 332 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 261 15.371 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMD44_RS38165 4a3e6c06ccb4029d3dbf609cadb9cefb 394 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 178 277 2.2E-12 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS38165 4a3e6c06ccb4029d3dbf609cadb9cefb 394 Gene3D G3DSA:3.40.50.1110 172 387 5.1E-26 T 28-03-2018 SMD44_RS38165 4a3e6c06ccb4029d3dbf609cadb9cefb 394 SUPERFAMILY SSF52266 172 381 1.83E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS16585 72cbbb4347e08bd74cdf4431aa8230eb 366 Gene3D G3DSA:2.60.40.10 168 245 5.0E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS16585 72cbbb4347e08bd74cdf4431aa8230eb 366 Gene3D G3DSA:2.60.40.230 25 127 9.3E-12 T 28-03-2018 SMD44_RS16585 72cbbb4347e08bd74cdf4431aa8230eb 366 SUPERFAMILY SSF49319 26 113 4.84E-5 T 28-03-2018 IPR027273 Neocarzinostatin-like SMD44_RS16880 822e85615ab88628037d6c023b05e224 262 SMART SM00382 49 235 6.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS16880 822e85615ab88628037d6c023b05e224 262 Pfam PF00005 ABC transporter 40 186 9.7E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS16880 822e85615ab88628037d6c023b05e224 262 SUPERFAMILY SSF52540 23 239 1.82E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16880 822e85615ab88628037d6c023b05e224 262 Gene3D G3DSA:3.40.50.300 17 261 1.3E-61 T 28-03-2018 SMD44_RS16880 822e85615ab88628037d6c023b05e224 262 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS27795 b9454a60d79e5c0941d96097b1fdbfcb 355 Pfam PF00583 Acetyltransferase (GNAT) family 275 332 2.5E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS27795 b9454a60d79e5c0941d96097b1fdbfcb 355 SUPERFAMILY SSF55729 234 342 1.13E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS27795 b9454a60d79e5c0941d96097b1fdbfcb 355 Gene3D G3DSA:3.40.630.30 72 350 6.3E-20 T 28-03-2018 SMD44_RS03330 b5fd3d09c072b6f15ea669f8151505a0 386 Pfam PF00144 Beta-lactamase 57 359 8.4E-60 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS03330 b5fd3d09c072b6f15ea669f8151505a0 386 SUPERFAMILY SSF56601 11 356 1.71E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS03330 b5fd3d09c072b6f15ea669f8151505a0 386 Gene3D G3DSA:3.40.710.10 7 373 4.4E-74 T 28-03-2018 SMD44_RS13410 0d6a1cba313a08775aed25d3b40aecc5 260 Pfam PF01925 Sulfite exporter TauE/SafE 13 253 2.5E-37 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 133 146 - T 28-03-2018 IPR033135 ClpP, histidine active site SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 Gene3D G3DSA:3.90.226.10 23 216 1.8E-37 T 28-03-2018 SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 PRINTS PR00127 Clp protease catalytic subunit P signature 80 100 7.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 PRINTS PR00127 Clp protease catalytic subunit P signature 190 209 7.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 PRINTS PR00127 Clp protease catalytic subunit P signature 111 128 7.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 PRINTS PR00127 Clp protease catalytic subunit P signature 132 151 7.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 PRINTS PR00127 Clp protease catalytic subunit P signature 40 55 7.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 111 122 - T 28-03-2018 IPR018215 ClpP, Ser active site SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 Pfam PF00574 Clp protease 34 214 3.4E-76 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 24 215 39.203 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD44_RS14145 cc3a48a4a8dd797a71cbaaf9de4efcc5 223 SUPERFAMILY SSF52096 32 216 6.5E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS30075 a3fc66f93b921397a34f57ae63a9e8df 403 SUPERFAMILY SSF82171 98 377 1.14E-19 T 28-03-2018 SMD44_RS30075 a3fc66f93b921397a34f57ae63a9e8df 403 Gene3D G3DSA:2.130.10.150 100 259 1.6E-12 T 28-03-2018 SMD44_RS30075 a3fc66f93b921397a34f57ae63a9e8df 403 Gene3D G3DSA:2.130.10.150 260 403 4.8E-9 T 28-03-2018 SMD44_RS07705 bb920478f7717a75897df609222010e5 158 Gene3D G3DSA:1.10.3430.10 5 142 9.9E-4 T 28-03-2018 SMD44_RS29010 741a581ab0b2b9b3c625b5c9f1117dbe 337 SUPERFAMILY SSF52540 2 225 4.95E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29010 741a581ab0b2b9b3c625b5c9f1117dbe 337 Pfam PF00005 ABC transporter 17 156 5.2E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS29010 741a581ab0b2b9b3c625b5c9f1117dbe 337 SMART SM00382 26 204 5.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS29010 741a581ab0b2b9b3c625b5c9f1117dbe 337 Gene3D G3DSA:3.40.50.300 1 307 4.1E-55 T 28-03-2018 SMD44_RS42570 9e02dd207980bf278ba4c8884aaaa780 122 Gene3D G3DSA:2.40.50.110 23 119 2.3E-9 T 28-03-2018 SMD44_RS42570 9e02dd207980bf278ba4c8884aaaa780 122 Pfam PF08239 Bacterial SH3 domain 61 117 3.0E-6 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type SMD44_RS33245 b2af80239a838a07935665c770ca4d82 136 SUPERFAMILY SSF54427 32 124 1.03E-22 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS33245 b2af80239a838a07935665c770ca4d82 136 Pfam PF14534 Domain of unknown function (DUF4440) 36 125 4.1E-8 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 SMD44_RS33245 b2af80239a838a07935665c770ca4d82 136 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 30 123 9.4E-18 T 28-03-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 SMD44_RS33245 b2af80239a838a07935665c770ca4d82 136 Gene3D G3DSA:3.10.450.50 21 133 4.2E-14 T 28-03-2018 SMD44_RS07405 7cce2988815595d995133ff74e04e86d 234 Pfam PF00753 Metallo-beta-lactamase superfamily 9 202 4.0E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS07405 7cce2988815595d995133ff74e04e86d 234 SUPERFAMILY SSF56281 6 224 1.31E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS07405 7cce2988815595d995133ff74e04e86d 234 SMART SM00849 12 202 1.2E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS07405 7cce2988815595d995133ff74e04e86d 234 Gene3D G3DSA:3.60.15.10 1 225 1.9E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS25130 46e4fa4767c8b12c88e2bc31660c359e 336 Pfam PF00348 Polyprenyl synthetase 41 254 3.2E-59 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMD44_RS25130 46e4fa4767c8b12c88e2bc31660c359e 336 Gene3D G3DSA:1.10.600.10 9 336 2.7E-92 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS25130 46e4fa4767c8b12c88e2bc31660c359e 336 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMD44_RS25130 46e4fa4767c8b12c88e2bc31660c359e 336 SUPERFAMILY SSF48576 20 334 4.75E-79 T 28-03-2018 IPR008949 Isoprenoid synthase domain SMD44_RS27945 29ceea8ddb8f5ac660bd2da7e32b5db9 295 Gene3D G3DSA:3.40.50.1010 19 196 2.7E-19 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS27945 29ceea8ddb8f5ac660bd2da7e32b5db9 295 Pfam PF01936 NYN domain 30 176 1.1E-10 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type SMD44_RS08140 cc46e77a28ba1a37424f51da2ee19993 269 SUPERFAMILY SSF56235 10 230 6.72E-44 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS08140 cc46e77a28ba1a37424f51da2ee19993 269 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 230 1.4E-117 T 28-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 SMD44_RS08140 cc46e77a28ba1a37424f51da2ee19993 269 Gene3D G3DSA:3.60.20.10 8 234 2.9E-43 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS08140 cc46e77a28ba1a37424f51da2ee19993 269 Pfam PF00227 Proteasome subunit 25 191 5.6E-28 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMD44_RS08140 cc46e77a28ba1a37424f51da2ee19993 269 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 234 49.312 T 28-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 SMD44_RS29195 2411749d2c4e13558a037d0c95aadf4f 327 Gene3D G3DSA:3.40.30.10 44 258 4.0E-40 T 28-03-2018 SMD44_RS29195 2411749d2c4e13558a037d0c95aadf4f 327 Pfam PF14559 Tetratricopeptide repeat 201 236 7.7E-7 T 28-03-2018 SMD44_RS29195 2411749d2c4e13558a037d0c95aadf4f 327 ProSitePatterns PS00194 Thioredoxin family active site. 74 92 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMD44_RS29195 2411749d2c4e13558a037d0c95aadf4f 327 SUPERFAMILY SSF52833 52 159 1.64E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS29195 2411749d2c4e13558a037d0c95aadf4f 327 Pfam PF00085 Thioredoxin 53 155 4.0E-24 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMD44_RS29195 2411749d2c4e13558a037d0c95aadf4f 327 Pfam PF14561 Tetratricopeptide repeat 241 327 1.3E-21 T 28-03-2018 SMD44_RS41890 23eee70a081ae4a388713a317ea82b83 379 Gene3D G3DSA:1.10.10.60 305 355 8.4E-6 T 28-03-2018 SMD44_RS41890 23eee70a081ae4a388713a317ea82b83 379 Pfam PF13556 PucR C-terminal helix-turn-helix domain 320 374 9.9E-16 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS06080 777b8eefcd937fad7c865078acee7dcb 125 Pfam PF12680 SnoaL-like domain 7 101 1.5E-13 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS06080 777b8eefcd937fad7c865078acee7dcb 125 Gene3D G3DSA:3.10.450.50 2 124 4.3E-20 T 28-03-2018 SMD44_RS06080 777b8eefcd937fad7c865078acee7dcb 125 SUPERFAMILY SSF54427 1 120 1.06E-29 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 PRINTS PR00359 B-class P450 signature 373 382 9.5E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 PRINTS PR00359 B-class P450 signature 306 317 9.5E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 PRINTS PR00359 B-class P450 signature 351 366 9.5E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 PRINTS PR00359 B-class P450 signature 94 105 9.5E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 PRINTS PR00359 B-class P450 signature 323 350 9.5E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 PRINTS PR00359 B-class P450 signature 147 163 9.5E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 PRINTS PR00359 B-class P450 signature 382 393 9.5E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 Gene3D G3DSA:1.10.630.10 1 433 4.4E-63 T 28-03-2018 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 SUPERFAMILY SSF48264 12 433 3.8E-77 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 Pfam PF00067 Cytochrome P450 258 404 2.9E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD44_RS33060 4990ebcf7dcde29317e83b754c687618 433 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 375 384 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD44_RS27625 72b486fc6dae10d646bc9aad44e0672b 60 Pfam PF05036 Sporulation related domain 12 41 3.2E-4 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SMD44_RS27625 72b486fc6dae10d646bc9aad44e0672b 60 Gene3D G3DSA:3.30.70.1070 7 53 8.3E-5 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 SMD44_RS24110 95cf852f07e16c5fc3b7f1e6d3f4fdc6 377 Gene3D G3DSA:3.40.50.720 1 320 5.2E-35 T 28-03-2018 SMD44_RS24110 95cf852f07e16c5fc3b7f1e6d3f4fdc6 377 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 236 4.7E-20 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS24110 95cf852f07e16c5fc3b7f1e6d3f4fdc6 377 SUPERFAMILY SSF51735 2 317 7.15E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS04015 20b8d8c3799dda1339cfc76f6790820f 883 Pfam PF02687 FtsX-like permease family 783 875 5.7E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS04015 20b8d8c3799dda1339cfc76f6790820f 883 Pfam PF02687 FtsX-like permease family 331 426 1.3E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS04015 20b8d8c3799dda1339cfc76f6790820f 883 Pfam PF12704 MacB-like periplasmic core domain 52 268 6.0E-14 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS04015 20b8d8c3799dda1339cfc76f6790820f 883 Pfam PF12704 MacB-like periplasmic core domain 524 724 3.3E-12 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS05040 17fbc6be1f80b2909cfd7b64a05dfbdb 223 Pfam PF01987 Mitochondrial biogenesis AIM24 34 214 1.5E-32 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS05040 17fbc6be1f80b2909cfd7b64a05dfbdb 223 SUPERFAMILY SSF51219 33 218 3.66E-45 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD44_RS05040 17fbc6be1f80b2909cfd7b64a05dfbdb 223 Gene3D G3DSA:3.60.160.10 25 221 5.4E-47 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS21685 3d775bc0caf4adc31bbffe6f2fa8e4d3 96 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 7 95 2.4E-44 T 28-03-2018 IPR009359 Phenylacetic acid degradation B SMD44_RS21685 3d775bc0caf4adc31bbffe6f2fa8e4d3 96 PIRSF PIRSF030200 1 96 3.8E-45 T 28-03-2018 IPR009359 Phenylacetic acid degradation B SMD44_RS21685 3d775bc0caf4adc31bbffe6f2fa8e4d3 96 Pfam PF06243 Phenylacetic acid degradation B 6 93 8.5E-41 T 28-03-2018 IPR009359 Phenylacetic acid degradation B SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 Pfam PF03466 LysR substrate binding domain 113 313 3.6E-50 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 SUPERFAMILY SSF53850 113 318 1.38E-43 T 28-03-2018 SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 64 75 8.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 8.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 64 8.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 Gene3D G3DSA:3.40.190.10 200 287 1.1E-26 T 28-03-2018 SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 Gene3D G3DSA:3.40.190.10 114 199 8.7E-24 T 28-03-2018 SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 87 4.5E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 Gene3D G3DSA:1.10.10.10 7 111 1.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26800 588fc057cc3d21fcd35e35afcf64a2e6 326 SUPERFAMILY SSF46785 30 109 1.77E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23720 3f4b2a0fa9f3bebacff71495171ee872 119 Gene3D G3DSA:3.30.1130.10 1 119 8.2E-38 T 28-03-2018 SMD44_RS23720 3f4b2a0fa9f3bebacff71495171ee872 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 116 1.5E-34 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD44_RS23720 3f4b2a0fa9f3bebacff71495171ee872 119 SMART SM00905 4 116 4.8E-50 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD44_RS23720 3f4b2a0fa9f3bebacff71495171ee872 119 Pfam PF02152 Dihydroneopterin aldolase 5 115 1.5E-35 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD44_RS23720 3f4b2a0fa9f3bebacff71495171ee872 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 2.1E-30 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD44_RS23720 3f4b2a0fa9f3bebacff71495171ee872 119 SUPERFAMILY SSF55620 2 118 7.23E-37 T 28-03-2018 SMD44_RS30525 fe531df048bc08ba9f2eec8880b3674e 102 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.4E-52 T 28-03-2018 IPR019592 Protein of unknown function DUF2469 SMD44_RS08885 0eb397cb19d0c6ee2f4a3c37b83fc098 330 SUPERFAMILY SSF161098 109 311 3.53E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS08885 0eb397cb19d0c6ee2f4a3c37b83fc098 330 Gene3D G3DSA:1.10.3720.10 3 317 1.7E-33 T 28-03-2018 SMD44_RS08885 0eb397cb19d0c6ee2f4a3c37b83fc098 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 328 8.3E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS40965 d94291adba8f6c07779f61b28adeeaa0 402 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 131 397 1.4E-85 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 SMD44_RS40965 d94291adba8f6c07779f61b28adeeaa0 402 SUPERFAMILY SSF56322 80 399 1.7E-90 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS40965 d94291adba8f6c07779f61b28adeeaa0 402 Pfam PF00425 chorismate binding enzyme 136 390 1.3E-73 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMD44_RS40965 d94291adba8f6c07779f61b28adeeaa0 402 Gene3D G3DSA:3.60.120.10 32 401 2.3E-101 T 28-03-2018 IPR005801 ADC synthase GO:0009058 SMD44_RS35620 42d77b382ec891ed69f9904e88539c4d 446 SUPERFAMILY SSF48452 194 397 4.93E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS35620 42d77b382ec891ed69f9904e88539c4d 446 Gene3D G3DSA:1.25.40.10 177 428 1.5E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS14550 db7319da72828e6aa8e8bc2ae3038593 252 SMART SM00345 12 71 4.1E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS14550 db7319da72828e6aa8e8bc2ae3038593 252 SUPERFAMILY SSF64288 59 250 2.98E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS14550 db7319da72828e6aa8e8bc2ae3038593 252 Pfam PF07702 UTRA domain 103 241 2.7E-28 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS14550 db7319da72828e6aa8e8bc2ae3038593 252 SUPERFAMILY SSF46785 10 89 2.63E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14550 db7319da72828e6aa8e8bc2ae3038593 252 Gene3D G3DSA:1.10.10.10 3 73 6.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS14550 db7319da72828e6aa8e8bc2ae3038593 252 SMART SM00866 103 244 7.6E-22 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD44_RS14550 db7319da72828e6aa8e8bc2ae3038593 252 Gene3D G3DSA:3.40.1410.10 77 247 1.7E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD44_RS14550 db7319da72828e6aa8e8bc2ae3038593 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.3E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 SUPERFAMILY SSF52540 5 208 1.51E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 Pfam PF16326 ABC transporter C-terminal domain 542 603 2.4E-9 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 Pfam PF12848 ABC transporter 198 272 3.5E-8 T 28-03-2018 IPR032781 ABC-transporter extension domain SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 Pfam PF00005 ABC transporter 306 447 1.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 Pfam PF00005 ABC transporter 21 159 5.3E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 SUPERFAMILY SSF52540 277 490 1.65E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 Gene3D G3DSA:3.40.50.300 287 600 1.8E-45 T 28-03-2018 SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 SMART SM00382 30 204 2.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 SMART SM00382 315 493 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS17050 498affaea813a229832faa481d73fa7e 605 Gene3D G3DSA:3.40.50.300 1 265 3.4E-51 T 28-03-2018 SMD44_RS22605 a84fd71748bb5e6fb0184512e88f58db 340 PIRSF PIRSF001359 5 338 2.8E-63 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD44_RS22605 a84fd71748bb5e6fb0184512e88f58db 340 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 336 1.0E-78 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD44_RS22605 a84fd71748bb5e6fb0184512e88f58db 340 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 336 4.0E-71 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD44_RS22605 a84fd71748bb5e6fb0184512e88f58db 340 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 335 4.3E-127 T 28-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 SMD44_RS22605 a84fd71748bb5e6fb0184512e88f58db 340 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD44_RS22605 a84fd71748bb5e6fb0184512e88f58db 340 Gene3D G3DSA:3.20.20.70 1 340 5.2E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS22605 a84fd71748bb5e6fb0184512e88f58db 340 SUPERFAMILY SSF51569 4 336 1.29E-95 T 28-03-2018 SMD44_RS38705 1e646f9407b6aa123e25c6b7aeca6501 655 Gene3D G3DSA:3.40.50.300 381 628 4.6E-54 T 28-03-2018 SMD44_RS38705 1e646f9407b6aa123e25c6b7aeca6501 655 Pfam PF00005 ABC transporter 401 560 1.4E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS38705 1e646f9407b6aa123e25c6b7aeca6501 655 Gene3D G3DSA:1.20.1560.10 47 367 4.0E-18 T 28-03-2018 SMD44_RS38705 1e646f9407b6aa123e25c6b7aeca6501 655 SMART SM00382 410 623 2.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS38705 1e646f9407b6aa123e25c6b7aeca6501 655 SUPERFAMILY SSF90123 51 348 2.88E-18 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS38705 1e646f9407b6aa123e25c6b7aeca6501 655 SUPERFAMILY SSF52540 380 631 6.58E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21875 f2d09eae415e642b036eb2686c52c015 159 Pfam PF07179 SseB protein N-terminal domain 46 147 1.8E-8 T 28-03-2018 IPR009839 SseB protein N-terminal domain SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.4E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 SUPERFAMILY SSF53850 126 288 2.71E-10 T 28-03-2018 SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 SUPERFAMILY SSF46785 4 88 1.01E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 Gene3D G3DSA:1.10.10.10 1 70 9.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 Pfam PF03466 LysR substrate binding domain 125 273 3.3E-10 T 28-03-2018 IPR005119 LysR, substrate-binding SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 Gene3D G3DSA:3.40.190.10 173 258 2.5E-4 T 28-03-2018 SMD44_RS03450 22bd2561b78f7fe996290e1e1d0d2d54 314 Gene3D G3DSA:3.40.190.10 71 172 4.8E-8 T 28-03-2018 SMD44_RS29380 d40655b1182c45718e1f36aa12ab97ec 792 Gene3D G3DSA:1.20.1640.10 178 395 2.4E-31 T 28-03-2018 SMD44_RS29380 d40655b1182c45718e1f36aa12ab97ec 792 Pfam PF03176 MMPL family 18 425 3.0E-42 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS29380 d40655b1182c45718e1f36aa12ab97ec 792 Pfam PF03176 MMPL family 494 779 3.5E-42 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS29380 d40655b1182c45718e1f36aa12ab97ec 792 Gene3D G3DSA:1.20.1640.10 563 773 2.9E-29 T 28-03-2018 SMD44_RS29380 d40655b1182c45718e1f36aa12ab97ec 792 SUPERFAMILY SSF82866 190 395 3.92E-31 T 28-03-2018 SMD44_RS29380 d40655b1182c45718e1f36aa12ab97ec 792 SUPERFAMILY SSF82866 571 775 8.11E-28 T 28-03-2018 SMD44_RS25095 58f279774d14076896a545c02d1e705b 431 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 137 426 7.7E-52 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS25095 58f279774d14076896a545c02d1e705b 431 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 47 428 3.6E-118 T 28-03-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMD44_RS25095 58f279774d14076896a545c02d1e705b 431 Gene3D G3DSA:3.90.850.10 129 414 1.5E-82 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS25095 58f279774d14076896a545c02d1e705b 431 Pfam PF09298 Fumarylacetoacetase N-terminal 18 131 5.5E-14 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMD44_RS25095 58f279774d14076896a545c02d1e705b 431 SUPERFAMILY SSF56529 133 427 3.27E-85 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS25095 58f279774d14076896a545c02d1e705b 431 SUPERFAMILY SSF63433 7 131 9.94E-19 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMD44_RS25095 58f279774d14076896a545c02d1e705b 431 Gene3D G3DSA:2.30.30.230 6 127 7.8E-24 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMD44_RS11385 7ce2597ad7cce89ee7fe6dffb8e2e27e 206 Gene3D G3DSA:1.20.120.80 20 206 2.9E-56 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11385 7ce2597ad7cce89ee7fe6dffb8e2e27e 206 SUPERFAMILY SSF81452 12 204 8.11E-55 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS11385 7ce2597ad7cce89ee7fe6dffb8e2e27e 206 Pfam PF00510 Cytochrome c oxidase subunit III 26 204 6.7E-24 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS35070 1d009075a1aec7a5ce05bd76faf6fee0 301 Pfam PF10708 Protein of unknown function (DUF2510) 9 42 2.3E-14 T 28-03-2018 IPR018929 Domain of unknown function DUF2510 SMD44_RS35070 1d009075a1aec7a5ce05bd76faf6fee0 301 SUPERFAMILY SSF54518 122 290 4.18E-11 T 28-03-2018 IPR025659 Tubby C-terminal-like domain SMD44_RS35070 1d009075a1aec7a5ce05bd76faf6fee0 301 Pfam PF03803 Scramblase 104 291 4.3E-19 T 28-03-2018 IPR005552 Scramblase SMD44_RS03370 e6f588758ede302c830f70e4c9c1c6a1 69 SMART SM00923 3 53 2.1E-33 T 28-03-2018 IPR005153 MbtH-like protein SMD44_RS03370 e6f588758ede302c830f70e4c9c1c6a1 69 Gene3D G3DSA:3.90.820.10 2 68 4.2E-36 T 28-03-2018 SMD44_RS03370 e6f588758ede302c830f70e4c9c1c6a1 69 SUPERFAMILY SSF160582 1 67 1.1E-31 T 28-03-2018 SMD44_RS03370 e6f588758ede302c830f70e4c9c1c6a1 69 Pfam PF03621 MbtH-like protein 1 52 6.9E-30 T 28-03-2018 IPR005153 MbtH-like protein SMD44_RS14575 9c2555aea8ba3283de38f3a585f07248 62 Pfam PF05122 Mobile element transfer protein 12 61 9.1E-28 T 28-03-2018 IPR007806 Mobile element transfer SMD44_RS16860 c1ecbf88eccdbf5c536cbb9fb16928bf 147 SUPERFAMILY SSF54427 16 145 4.25E-24 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS16860 c1ecbf88eccdbf5c536cbb9fb16928bf 147 Gene3D G3DSA:3.10.450.50 1 146 1.3E-18 T 28-03-2018 SMD44_RS16860 c1ecbf88eccdbf5c536cbb9fb16928bf 147 Pfam PF12680 SnoaL-like domain 23 132 2.2E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS10470 56b5477794269249e658a4536ab39253 126 Pfam PF12158 Protein of unknown function (DUF3592) 6 124 5.1E-6 T 28-03-2018 IPR021994 Protein of unknown function DUF3592 SMD44_RS10035 7317b4daeb0a9077eeb237628cfb7c16 238 Pfam PF01061 ABC-2 type transporter 10 205 9.9E-23 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS10035 7317b4daeb0a9077eeb237628cfb7c16 238 PIRSF PIRSF006648 3 238 3.1E-33 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS42660 04761cd122c914c67df212e0893507f4 262 Gene3D G3DSA:3.40.50.300 25 259 3.0E-11 T 28-03-2018 SMD44_RS42660 04761cd122c914c67df212e0893507f4 262 SUPERFAMILY SSF52540 30 217 4.09E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS12755 8388783576bd9c21745c0bc6dca7d6c5 217 Gene3D G3DSA:2.60.120.10 134 217 9.4E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS12755 8388783576bd9c21745c0bc6dca7d6c5 217 Pfam PF02678 Pirin 17 119 3.4E-29 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SMD44_RS12755 8388783576bd9c21745c0bc6dca7d6c5 217 PIRSF PIRSF006232 2 214 1.2E-36 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 SMD44_RS12755 8388783576bd9c21745c0bc6dca7d6c5 217 SUPERFAMILY SSF51182 16 216 7.09E-49 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS12755 8388783576bd9c21745c0bc6dca7d6c5 217 Gene3D G3DSA:2.60.120.10 16 133 1.3E-39 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS13505 87ec4600ea7a93e0c1229d05ae2dbf68 481 Gene3D G3DSA:1.20.1250.20 27 219 1.7E-30 T 28-03-2018 SMD44_RS13505 87ec4600ea7a93e0c1229d05ae2dbf68 481 Gene3D G3DSA:1.20.1250.20 273 480 3.6E-17 T 28-03-2018 SMD44_RS13505 87ec4600ea7a93e0c1229d05ae2dbf68 481 Pfam PF07690 Major Facilitator Superfamily 33 434 2.7E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS13505 87ec4600ea7a93e0c1229d05ae2dbf68 481 SUPERFAMILY SSF103473 6 215 8.11E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS13505 87ec4600ea7a93e0c1229d05ae2dbf68 481 SUPERFAMILY SSF103473 269 473 8.11E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03405 f7a00718bcf962f50d4d15b9ac202318 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 264 1.8E-54 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS03405 f7a00718bcf962f50d4d15b9ac202318 266 Gene3D G3DSA:3.90.226.10 3 223 2.0E-64 T 28-03-2018 SMD44_RS03405 f7a00718bcf962f50d4d15b9ac202318 266 Gene3D G3DSA:1.10.12.10 224 266 5.5E-17 T 28-03-2018 IPR014748 Crontonase, C-terminal SMD44_RS03405 f7a00718bcf962f50d4d15b9ac202318 266 SUPERFAMILY SSF52096 4 264 3.87E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS05570 89e0497ccdc3bc5033af00f83bf83a1f 258 SUPERFAMILY SSF55729 73 254 1.17E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS05570 89e0497ccdc3bc5033af00f83bf83a1f 258 Gene3D G3DSA:3.40.630.30 115 254 1.2E-16 T 28-03-2018 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 Gene3D G3DSA:3.30.565.10 320 468 6.5E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 461 2.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 SMART SM00387 358 464 3.8E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 SMART SM00388 245 316 7.1E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 Gene3D G3DSA:1.10.287.130 235 312 2.0E-13 T 28-03-2018 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 SUPERFAMILY SSF55874 306 462 4.85E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 Pfam PF00672 HAMP domain 189 239 5.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 SUPERFAMILY SSF47384 228 315 1.28E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 4.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 4.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 4.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 4.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 SUPERFAMILY SSF158472 192 241 1.7E-5 T 28-03-2018 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 SMART SM00304 189 244 9.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS19320 e96048bccf94058d30a729893be68d7a 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 315 1.8E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS34415 e4302195d910980708f78d4ce46c5d48 132 Gene3D G3DSA:3.20.20.70 1 122 8.3E-29 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS34415 e4302195d910980708f78d4ce46c5d48 132 SUPERFAMILY SSF54631 5 122 1.89E-32 T 28-03-2018 SMD44_RS34415 e4302195d910980708f78d4ce46c5d48 132 Pfam PF00571 CBS domain 75 122 1.9E-13 T 28-03-2018 IPR000644 CBS domain SMD44_RS34415 e4302195d910980708f78d4ce46c5d48 132 Pfam PF00571 CBS domain 8 58 4.5E-12 T 28-03-2018 IPR000644 CBS domain SMD44_RS34415 e4302195d910980708f78d4ce46c5d48 132 SMART SM00116 80 127 5.4E-7 T 28-03-2018 IPR000644 CBS domain SMD44_RS34415 e4302195d910980708f78d4ce46c5d48 132 SMART SM00116 15 62 1.3E-7 T 28-03-2018 IPR000644 CBS domain SMD44_RS27935 0e161baf8c45eeec880eedffe1b783ea 200 Pfam PF01914 MarC family integral membrane protein 6 196 1.0E-44 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 SMD44_RS27935 0e161baf8c45eeec880eedffe1b783ea 200 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 193 1.5E-40 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 SMD44_RS27490 30be31962edc07ed50fbe58891390a90 227 Pfam PF04167 Protein of unknown function (DUF402) 97 161 2.9E-15 T 28-03-2018 IPR007295 Domain of unknown function DUF402 SMD44_RS27490 30be31962edc07ed50fbe58891390a90 227 SUPERFAMILY SSF159234 40 210 7.85E-46 T 28-03-2018 IPR007295 Domain of unknown function DUF402 SMD44_RS27490 30be31962edc07ed50fbe58891390a90 227 Gene3D G3DSA:2.40.380.10 14 208 3.1E-82 T 28-03-2018 IPR007295 Domain of unknown function DUF402 SMD44_RS08330 cd3f0f1321cb537b22e9315610b7fc0f 329 SUPERFAMILY SSF51430 1 318 6.81E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS08330 cd3f0f1321cb537b22e9315610b7fc0f 329 Pfam PF00248 Aldo/keto reductase family 15 314 1.1E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS08330 cd3f0f1321cb537b22e9315610b7fc0f 329 Gene3D G3DSA:3.20.20.100 1 329 1.9E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS29180 b0efb46f4ee5a024c09741bd01d0055a 398 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 23 388 30.656 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS29180 b0efb46f4ee5a024c09741bd01d0055a 398 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 23 158 1.0E-28 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD44_RS29180 b0efb46f4ee5a024c09741bd01d0055a 398 Gene3D G3DSA:3.40.50.2000 196 385 2.7E-31 T 28-03-2018 SMD44_RS29180 b0efb46f4ee5a024c09741bd01d0055a 398 SUPERFAMILY SSF53756 23 388 5.56E-87 T 28-03-2018 SMD44_RS29180 b0efb46f4ee5a024c09741bd01d0055a 398 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 214 372 2.2E-34 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SMD44_RS29180 b0efb46f4ee5a024c09741bd01d0055a 398 Gene3D G3DSA:3.40.50.2000 15 195 3.0E-30 T 28-03-2018 SMD44_RS03740 d68318b7465f1ddba3ece676f741ac05 424 SUPERFAMILY SSF103473 11 399 3.53E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS03740 d68318b7465f1ddba3ece676f741ac05 424 Pfam PF07690 Major Facilitator Superfamily 12 229 1.2E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS03740 d68318b7465f1ddba3ece676f741ac05 424 Gene3D G3DSA:1.20.1250.20 1 198 2.1E-15 T 28-03-2018 SMD44_RS03740 d68318b7465f1ddba3ece676f741ac05 424 Gene3D G3DSA:1.20.1250.20 202 406 1.6E-18 T 28-03-2018 SMD44_RS15190 a7c7f11df2db621fb9af623a6e6013a6 165 SUPERFAMILY SSF50891 10 150 5.69E-11 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS15190 a7c7f11df2db621fb9af623a6e6013a6 165 Pfam PF12903 Protein of unknown function (DUF3830) 11 164 4.1E-64 T 28-03-2018 IPR024532 Protein of unknown function DUF3830 SMD44_RS42285 b8c16e474fa10b1d70aaf684e9d0a779 193 Gene3D G3DSA:3.30.70.890 82 161 7.5E-4 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain SMD44_RS24465 f52ebc16eea4cd5433e0df5060cdf6c4 503 Gene3D G3DSA:1.20.1250.20 35 226 1.1E-28 T 28-03-2018 SMD44_RS24465 f52ebc16eea4cd5433e0df5060cdf6c4 503 Gene3D G3DSA:1.20.1250.20 285 495 1.2E-34 T 28-03-2018 SMD44_RS24465 f52ebc16eea4cd5433e0df5060cdf6c4 503 SUPERFAMILY SSF103473 274 483 9.16E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS24465 f52ebc16eea4cd5433e0df5060cdf6c4 503 SUPERFAMILY SSF103473 24 224 9.16E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS24465 f52ebc16eea4cd5433e0df5060cdf6c4 503 Pfam PF07690 Major Facilitator Superfamily 46 435 9.5E-58 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS02885 e5e106b2a97af35f03c9d82b2c188093 132 Pfam PF04266 ASCH domain 18 130 1.4E-13 T 28-03-2018 IPR007374 ASCH domain SMD44_RS02885 e5e106b2a97af35f03c9d82b2c188093 132 SUPERFAMILY SSF88697 16 130 1.17E-24 T 28-03-2018 IPR015947 PUA-like domain SMD44_RS02885 e5e106b2a97af35f03c9d82b2c188093 132 SMART SM01022 17 130 5.0E-15 T 28-03-2018 IPR007374 ASCH domain SMD44_RS02885 e5e106b2a97af35f03c9d82b2c188093 132 Gene3D G3DSA:3.10.400.10 4 132 1.9E-36 T 28-03-2018 SMD44_RS35495 eb91228a86c9f1e731699e0d9b560b96 309 Pfam PF01061 ABC-2 type transporter 61 267 1.4E-17 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS16690 81d45c95b57004167464a07a8a12be22 474 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 14 435 1.1E-54 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMD44_RS16690 81d45c95b57004167464a07a8a12be22 474 PRINTS PR00173 Glutamate-aspartate symporter signature 268 290 4.2E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS16690 81d45c95b57004167464a07a8a12be22 474 PRINTS PR00173 Glutamate-aspartate symporter signature 132 157 4.2E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS16690 81d45c95b57004167464a07a8a12be22 474 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 4.2E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD44_RS16690 81d45c95b57004167464a07a8a12be22 474 PIRSF PIRSF002744 2 458 1.5E-109 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMD44_RS04040 c2320994a62c03d10a83307e34bfe1cb 195 Pfam PF16157 Domain of unknown function (DUF4865) 1 182 1.0E-67 T 28-03-2018 IPR032349 Protein of unknown function DUF4865 SMD44_RS22720 30c1de3b77e4a94d0e704bea6ada711b 265 SUPERFAMILY SSF55154 75 236 1.05E-5 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 SMD44_RS22720 30c1de3b77e4a94d0e704bea6ada711b 265 Gene3D G3DSA:2.40.320.10 37 245 1.9E-18 T 28-03-2018 SMD44_RS02650 7a989905ace41675be19ca3555bb0821 338 Pfam PF13411 MerR HTH family regulatory protein 39 104 8.7E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02650 7a989905ace41675be19ca3555bb0821 338 SUPERFAMILY SSF46955 38 143 2.16E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS02650 7a989905ace41675be19ca3555bb0821 338 Gene3D G3DSA:1.10.1660.10 95 174 0.021 T 28-03-2018 SMD44_RS02650 7a989905ace41675be19ca3555bb0821 338 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 74 94 2.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02650 7a989905ace41675be19ca3555bb0821 338 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 50 63 2.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02650 7a989905ace41675be19ca3555bb0821 338 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 50 2.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02650 7a989905ace41675be19ca3555bb0821 338 SMART SM00422 38 107 2.5E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS02650 7a989905ace41675be19ca3555bb0821 338 Gene3D G3DSA:1.10.1660.10 33 94 2.0E-21 T 28-03-2018 SMD44_RS15335 c91fd9a9f4351c55cfa81b98067e1ad8 645 Pfam PF09118 Domain of unknown function (DUF1929) 551 644 6.2E-19 T 28-03-2018 IPR015202 Galactose oxidase-like, Early set domain SMD44_RS15335 c91fd9a9f4351c55cfa81b98067e1ad8 645 Gene3D G3DSA:2.130.10.80 49 551 3.2E-71 T 28-03-2018 IPR015916 Galactose oxidase, beta-propeller SMD44_RS15335 c91fd9a9f4351c55cfa81b98067e1ad8 645 SUPERFAMILY SSF50965 264 546 2.48E-34 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller SMD44_RS15335 c91fd9a9f4351c55cfa81b98067e1ad8 645 SUPERFAMILY SSF50965 49 138 3.4E-6 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller SMD44_RS15335 c91fd9a9f4351c55cfa81b98067e1ad8 645 Gene3D G3DSA:2.60.40.10 552 645 4.9E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS15335 c91fd9a9f4351c55cfa81b98067e1ad8 645 SUPERFAMILY SSF81296 546 644 2.66E-18 T 28-03-2018 IPR014756 Immunoglobulin E-set SMD44_RS20575 a626b67a9fc87bce571a24fa3a35f1f8 381 SUPERFAMILY SSF52540 49 191 1.6E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS20575 a626b67a9fc87bce571a24fa3a35f1f8 381 Pfam PF12307 Protein of unknown function (DUF3631) 175 362 1.6E-70 T 28-03-2018 IPR022081 Domain of unknown function DUF3631 SMD44_RS20575 a626b67a9fc87bce571a24fa3a35f1f8 381 Gene3D G3DSA:3.40.50.300 43 176 1.9E-4 T 28-03-2018 SMD44_RS10955 78ffc386a2a030eb63d8029138ee042b 153 Gene3D G3DSA:3.40.630.30 1 153 1.0E-36 T 28-03-2018 SMD44_RS10955 78ffc386a2a030eb63d8029138ee042b 153 Pfam PF13673 Acetyltransferase (GNAT) domain 62 152 4.3E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS10955 78ffc386a2a030eb63d8029138ee042b 153 SUPERFAMILY SSF55729 3 152 1.01E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 Gene3D G3DSA:3.40.50.300 288 549 5.7E-52 T 28-03-2018 SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 SMART SM00382 346 516 2.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 SMART SM00382 30 239 2.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 Pfam PF00005 ABC transporter 21 188 5.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 Pfam PF00005 ABC transporter 338 471 1.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 SUPERFAMILY SSF52540 307 514 2.15E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 Pfam PF12848 ABC transporter 227 297 5.4E-12 T 28-03-2018 IPR032781 ABC-transporter extension domain SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 SUPERFAMILY SSF52540 8 238 1.57E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 Gene3D G3DSA:3.40.50.300 2 287 7.4E-56 T 28-03-2018 SMD44_RS14540 da73a30bcba432fd97eca18ba9662071 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 551 8.5E-274 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD SMD44_RS03165 eb384093448af1ad66a03751f8fe3556 261 Pfam PF12730 ABC-2 family transporter protein 18 138 1.6E-6 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS15310 d795c884ccdf515b4f9131f496d78c99 442 SMART SM00244 219 382 4.4E-4 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS15310 d795c884ccdf515b4f9131f496d78c99 442 SUPERFAMILY SSF117892 257 387 8.89E-9 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS15310 d795c884ccdf515b4f9131f496d78c99 442 Pfam PF01145 SPFH domain / Band 7 family 229 390 1.7E-20 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS07855 aec5b03b4ce1c96a33eb4a47f343365f 334 SUPERFAMILY SSF103481 233 332 2.62E-7 T 28-03-2018 SMD44_RS07855 aec5b03b4ce1c96a33eb4a47f343365f 334 Pfam PF00892 EamA-like transporter family 196 328 7.2E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS07855 aec5b03b4ce1c96a33eb4a47f343365f 334 Pfam PF00892 EamA-like transporter family 54 183 2.0E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS07855 aec5b03b4ce1c96a33eb4a47f343365f 334 SUPERFAMILY SSF103481 88 186 8.24E-8 T 28-03-2018 SMD44_RS19605 5e39b01e8e8c8988caeec726130c8544 314 SUPERFAMILY SSF51430 4 312 5.63E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS19605 5e39b01e8e8c8988caeec726130c8544 314 Gene3D G3DSA:3.20.20.100 4 314 2.1E-77 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS19605 5e39b01e8e8c8988caeec726130c8544 314 PRINTS PR00069 Aldo-keto reductase signature 109 127 3.6E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS19605 5e39b01e8e8c8988caeec726130c8544 314 PRINTS PR00069 Aldo-keto reductase signature 140 157 3.6E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS19605 5e39b01e8e8c8988caeec726130c8544 314 Pfam PF00248 Aldo/keto reductase family 16 312 1.3E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS03185 76ce80459dda1a70f419639dcd096232 470 SUPERFAMILY SSF81606 339 468 4.97E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS03185 76ce80459dda1a70f419639dcd096232 470 SMART SM00331 256 468 8.7E-19 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS03185 76ce80459dda1a70f419639dcd096232 470 SUPERFAMILY SSF55785 103 208 1.27E-12 T 28-03-2018 IPR000014 PAS domain SMD44_RS03185 76ce80459dda1a70f419639dcd096232 470 Gene3D G3DSA:3.30.450.20 14 217 6.9E-20 T 28-03-2018 SMD44_RS03185 76ce80459dda1a70f419639dcd096232 470 Gene3D G3DSA:3.60.40.10 218 470 2.2E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS03185 76ce80459dda1a70f419639dcd096232 470 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 286 468 5.3E-43 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS03185 76ce80459dda1a70f419639dcd096232 470 Pfam PF08447 PAS fold 114 195 8.8E-12 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 SMD44_RS33130 6a37dd1bdd03b79c93adaae599b9c2cb 147 Pfam PF06841 T4-like virus tail tube protein gp19 11 144 1.2E-29 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMD44_RS33130 6a37dd1bdd03b79c93adaae599b9c2cb 147 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 7 146 5.9E-38 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 SMD44_RS41770 15edb7a98c3c4a2b766b5ae1ce5fcf07 191 SUPERFAMILY SSF48498 80 183 2.94E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS41770 15edb7a98c3c4a2b766b5ae1ce5fcf07 191 Gene3D G3DSA:1.10.10.60 7 58 3.7E-19 T 28-03-2018 SMD44_RS41770 15edb7a98c3c4a2b766b5ae1ce5fcf07 191 Gene3D G3DSA:1.10.357.10 59 184 3.0E-20 T 28-03-2018 SMD44_RS41770 15edb7a98c3c4a2b766b5ae1ce5fcf07 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS41770 15edb7a98c3c4a2b766b5ae1ce5fcf07 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS41770 15edb7a98c3c4a2b766b5ae1ce5fcf07 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 4.5E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS41770 15edb7a98c3c4a2b766b5ae1ce5fcf07 191 SUPERFAMILY SSF46689 8 67 6.48E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS07845 3d6e56a3e6e1bf5efafc84a166dd3268 153 Pfam PF00583 Acetyltransferase (GNAT) family 62 138 3.4E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS07845 3d6e56a3e6e1bf5efafc84a166dd3268 153 Gene3D G3DSA:3.40.630.30 17 149 1.4E-17 T 28-03-2018 SMD44_RS07845 3d6e56a3e6e1bf5efafc84a166dd3268 153 SUPERFAMILY SSF55729 30 145 3.19E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS13050 7020cbfe51651537dbc56c6947ecc9c0 304 SUPERFAMILY SSF52540 3 224 2.27E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13050 7020cbfe51651537dbc56c6947ecc9c0 304 Pfam PF00005 ABC transporter 19 167 1.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS13050 7020cbfe51651537dbc56c6947ecc9c0 304 Gene3D G3DSA:3.40.50.300 1 236 7.7E-60 T 28-03-2018 SMD44_RS13050 7020cbfe51651537dbc56c6947ecc9c0 304 SMART SM00382 27 211 7.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS13115 241298f9f5155f8032741529b52598a1 237 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 51 207 2.7E-31 T 28-03-2018 IPR013382 CRISPR-associated protein Cse2 SMD44_RS13115 241298f9f5155f8032741529b52598a1 237 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 63 207 2.8E-34 T 28-03-2018 IPR013382 CRISPR-associated protein Cse2 SMD44_RS39435 8334c71ad495ef3a72eda5f1dae9fc05 355 SUPERFAMILY SSF53659 2 354 1.3E-110 T 28-03-2018 SMD44_RS39435 8334c71ad495ef3a72eda5f1dae9fc05 355 Gene3D G3DSA:3.40.718.10 1 355 7.8E-111 T 28-03-2018 SMD44_RS39435 8334c71ad495ef3a72eda5f1dae9fc05 355 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 SMD44_RS39435 8334c71ad495ef3a72eda5f1dae9fc05 355 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 349 1.4E-84 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD44_RS39435 8334c71ad495ef3a72eda5f1dae9fc05 355 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 353 2.1E-153 T 28-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 SMD44_RS39435 8334c71ad495ef3a72eda5f1dae9fc05 355 SMART SM01329 5 351 1.4E-156 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD44_RS09395 3bcf17f903fe4895ab74e35b13df36e0 129 Pfam PF11298 Protein of unknown function (DUF3099) 11 79 6.3E-24 T 28-03-2018 IPR021449 Protein of unknown function DUF3099 SMD44_RS35390 74e24976066d0b08dc46586eefd9941a 551 ProSitePatterns PS01303 BCCT family of transporters signature. 309 318 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 SMD44_RS35390 74e24976066d0b08dc46586eefd9941a 551 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 2 492 4.0E-176 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SMD44_RS35390 74e24976066d0b08dc46586eefd9941a 551 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 40 492 8.8E-161 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SMD44_RS01805 b5336d705a4b19f8737dfe8b3ec24e82 244 SUPERFAMILY SSF55729 2 135 4.18E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS01805 b5336d705a4b19f8737dfe8b3ec24e82 244 Gene3D G3DSA:3.40.630.30 1 153 7.9E-11 T 28-03-2018 SMD44_RS28250 0c24dca68fef71086c32f7ee5c50fe36 240 Pfam PF13398 Peptidase M50B-like 30 232 2.9E-63 T 28-03-2018 SMD44_RS14605 5a2a38ec990c4542fce121792ab083ef 64 SUPERFAMILY SSF46955 8 60 2.01E-9 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS14605 5a2a38ec990c4542fce121792ab083ef 64 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 57 1.7E-8 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD44_RS14605 5a2a38ec990c4542fce121792ab083ef 64 Pfam PF12728 Helix-turn-helix domain 9 59 4.3E-13 T 28-03-2018 SMD44_RS14605 5a2a38ec990c4542fce121792ab083ef 64 Gene3D G3DSA:1.10.10.10 9 63 1.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21580 bfb42a78befe07e3a280db439c08ff49 209 Gene3D G3DSA:1.10.357.10 65 195 3.1E-11 T 28-03-2018 SMD44_RS21580 bfb42a78befe07e3a280db439c08ff49 209 SUPERFAMILY SSF46689 6 71 2.62E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS21580 bfb42a78befe07e3a280db439c08ff49 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21580 bfb42a78befe07e3a280db439c08ff49 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 61 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS21580 bfb42a78befe07e3a280db439c08ff49 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21580 bfb42a78befe07e3a280db439c08ff49 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS21580 bfb42a78befe07e3a280db439c08ff49 209 SUPERFAMILY SSF48498 80 201 1.18E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS21580 bfb42a78befe07e3a280db439c08ff49 209 Gene3D G3DSA:1.10.10.60 2 64 1.1E-17 T 28-03-2018 SMD44_RS00840 27b3807af655a971b93b319a30f0ee9f 363 SUPERFAMILY SSF56601 16 338 4.51E-62 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS00840 27b3807af655a971b93b319a30f0ee9f 363 Pfam PF00144 Beta-lactamase 20 317 2.3E-48 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS00840 27b3807af655a971b93b319a30f0ee9f 363 Gene3D G3DSA:3.40.710.10 16 352 8.6E-61 T 28-03-2018 SMD44_RS10670 c78d055caad2beff585be9e9c0f3889f 246 SUPERFAMILY SSF53300 38 190 2.23E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS10670 c78d055caad2beff585be9e9c0f3889f 246 SMART SM00327 37 211 1.3E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS10670 c78d055caad2beff585be9e9c0f3889f 246 Pfam PF10138 vWA found in TerF C terminus 37 239 1.3E-63 T 28-03-2018 IPR019303 vWA found in TerF C terminus SMD44_RS10670 c78d055caad2beff585be9e9c0f3889f 246 Gene3D G3DSA:3.40.50.410 30 218 4.9E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS06555 7ed75c61f8fe792f06ef3cfda32847d4 205 Pfam PF03551 Transcriptional regulator PadR-like family 70 138 2.6E-20 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS06555 7ed75c61f8fe792f06ef3cfda32847d4 205 SUPERFAMILY SSF46785 55 148 2.14E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS06555 7ed75c61f8fe792f06ef3cfda32847d4 205 Gene3D G3DSA:1.10.10.10 57 200 2.5E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07385 36a0210e726a56229e65bb5b2f2ecff4 295 PIRSF PIRSF006648 3 294 2.5E-28 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS07385 36a0210e726a56229e65bb5b2f2ecff4 295 Pfam PF01061 ABC-2 type transporter 45 249 6.1E-27 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS20035 64ea04d18953b2bfee97de71cd4111bf 502 Gene3D G3DSA:3.40.50.880 195 476 4.6E-12 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS05135 896a23861e855c5c6877d0721f2ea7bb 457 Pfam PF00939 Sodium:sulfate symporter transmembrane region 283 404 8.0E-6 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 SMD44_RS05135 896a23861e855c5c6877d0721f2ea7bb 457 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 149 1.2E-55 T 28-03-2018 IPR009827 Dicarboxylate carrier MatC N-terminal SMD44_RS27530 0838cf39bfa0d758218c74c86292f99c 196 SUPERFAMILY SSF55469 14 194 6.41E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS27530 0838cf39bfa0d758218c74c86292f99c 196 Pfam PF00881 Nitroreductase family 15 174 3.2E-16 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD44_RS27530 0838cf39bfa0d758218c74c86292f99c 196 Gene3D G3DSA:3.40.109.10 6 196 1.4E-33 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS21460 5f463589ccaafc6e4da2b2e864a46ccc 470 Pfam PF01098 Cell cycle protein 83 449 6.0E-80 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SMD44_RS15655 7a4263e9ea549803e19fe1faf2bb4d4d 95 Pfam PF02597 ThiS family 5 93 9.8E-18 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMD44_RS15655 7a4263e9ea549803e19fe1faf2bb4d4d 95 SUPERFAMILY SSF54285 1 93 1.8E-23 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMD44_RS15655 7a4263e9ea549803e19fe1faf2bb4d4d 95 Gene3D G3DSA:3.10.20.30 1 94 1.1E-21 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS06695 a86aa5304903e34d2c5cb96b0d7e6eea 177 ProSitePatterns PS00893 Nudix box signature. 82 103 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD44_RS06695 a86aa5304903e34d2c5cb96b0d7e6eea 177 Pfam PF00293 NUDIX domain 53 159 3.4E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS06695 a86aa5304903e34d2c5cb96b0d7e6eea 177 SUPERFAMILY SSF55811 13 175 7.99E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS06695 a86aa5304903e34d2c5cb96b0d7e6eea 177 Gene3D G3DSA:3.90.79.10 22 172 5.8E-18 T 28-03-2018 SMD44_RS02085 6fbb37618910c404bf89e95376fb67f4 229 SUPERFAMILY SSF55469 131 228 9.95E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS02085 6fbb37618910c404bf89e95376fb67f4 229 SUPERFAMILY SSF55469 13 79 9.95E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS02085 6fbb37618910c404bf89e95376fb67f4 229 Pfam PF00881 Nitroreductase family 17 204 1.5E-25 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD44_RS02085 6fbb37618910c404bf89e95376fb67f4 229 Gene3D G3DSA:3.40.109.10 1 225 6.3E-48 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS36805 abdf6b5180577ea6011f9b0decee327a 159 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 134 1.2E-39 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS36805 abdf6b5180577ea6011f9b0decee327a 159 SUPERFAMILY SSF53901 1 127 1.01E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36805 abdf6b5180577ea6011f9b0decee327a 159 Gene3D G3DSA:3.40.47.10 1 155 3.7E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS36805 abdf6b5180577ea6011f9b0decee327a 159 SMART SM00825 Beta-ketoacyl synthase 1 159 2.1E-10 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS38945 67f1f6836be51ae3110684824cde71aa 138 Gene3D G3DSA:1.10.10.10 1 129 5.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38945 67f1f6836be51ae3110684824cde71aa 138 SUPERFAMILY SSF46785 12 109 4.61E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS38945 67f1f6836be51ae3110684824cde71aa 138 SMART SM00418 16 106 2.0E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS38945 67f1f6836be51ae3110684824cde71aa 138 Pfam PF01022 Bacterial regulatory protein, arsR family 23 67 4.0E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS13765 504f55ddf824587768c7d091d5905735 117 PRINTS PR00332 Histidine triad family signature 97 107 6.7E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SMD44_RS13765 504f55ddf824587768c7d091d5905735 117 PRINTS PR00332 Histidine triad family signature 10 26 6.7E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SMD44_RS13765 504f55ddf824587768c7d091d5905735 117 PRINTS PR00332 Histidine triad family signature 31 49 6.7E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SMD44_RS13765 504f55ddf824587768c7d091d5905735 117 Pfam PF01230 HIT domain 17 110 2.8E-23 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SMD44_RS13765 504f55ddf824587768c7d091d5905735 117 SUPERFAMILY SSF54197 7 116 3.71E-33 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS13765 504f55ddf824587768c7d091d5905735 117 Gene3D G3DSA:3.30.428.10 2 110 9.6E-32 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS16145 c71d18310073832b207d9b59360c0581 293 PIRSF PIRSF000103 1 293 5.1E-30 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS16145 c71d18310073832b207d9b59360c0581 293 SUPERFAMILY SSF51735 9 163 1.66E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS16145 c71d18310073832b207d9b59360c0581 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 161 2.5E-14 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS16145 c71d18310073832b207d9b59360c0581 293 Gene3D G3DSA:3.40.50.720 6 163 2.7E-21 T 28-03-2018 SMD44_RS16145 c71d18310073832b207d9b59360c0581 293 Gene3D G3DSA:1.10.1040.10 178 293 4.2E-8 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS15665 b132be672df448182eadff433835e2ba 332 Gene3D G3DSA:1.10.3470.10 1 331 1.6E-69 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS15665 b132be672df448182eadff433835e2ba 332 Pfam PF01032 FecCD transport family 8 323 2.8E-91 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS15665 b132be672df448182eadff433835e2ba 332 SUPERFAMILY SSF81345 3 323 9.29E-79 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS13675 69e414320a0ec6328d2fd56222ce83a4 479 SUPERFAMILY SSF55874 301 379 9.18E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13675 69e414320a0ec6328d2fd56222ce83a4 479 Pfam PF07730 Histidine kinase 208 278 5.8E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS13675 69e414320a0ec6328d2fd56222ce83a4 479 Gene3D G3DSA:3.30.565.10 180 476 2.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13675 69e414320a0ec6328d2fd56222ce83a4 479 SMART SM00387 327 477 6.2E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16320 4abd798c7449e1ffae76b86a91704b3d 418 Pfam PF14258 Domain of unknown function (DUF4350) 45 115 1.4E-13 T 28-03-2018 IPR025646 Domain of unknown function DUF4350 SMD44_RS02605 bcf6204fa4dea4d0a7417f25869da694 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 84 3.1E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02605 bcf6204fa4dea4d0a7417f25869da694 220 SUPERFAMILY SSF46689 25 109 3.01E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS02605 bcf6204fa4dea4d0a7417f25869da694 220 Gene3D G3DSA:1.10.357.10 103 217 4.4E-14 T 28-03-2018 SMD44_RS02605 bcf6204fa4dea4d0a7417f25869da694 220 Gene3D G3DSA:1.10.10.60 5 68 9.7E-16 T 28-03-2018 SMD44_RS02605 bcf6204fa4dea4d0a7417f25869da694 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02605 bcf6204fa4dea4d0a7417f25869da694 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02605 bcf6204fa4dea4d0a7417f25869da694 220 Gene3D G3DSA:1.10.260.40 69 102 2.4E-5 T 28-03-2018 SMD44_RS02605 bcf6204fa4dea4d0a7417f25869da694 220 SUPERFAMILY SSF48498 104 210 1.34E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS01110 b77ad99f73b53f852e06a1903cffe3c8 280 Gene3D G3DSA:3.40.50.1820 17 280 7.5E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS01110 b77ad99f73b53f852e06a1903cffe3c8 280 Pfam PF01738 Dienelactone hydrolase family 35 157 5.1E-7 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SMD44_RS01110 b77ad99f73b53f852e06a1903cffe3c8 280 SUPERFAMILY SSF53474 17 213 6.9E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS32355 58ca132c6c7fcedd25cb7167175dba2e 344 SUPERFAMILY SSF89372 5 287 8.63E-20 T 28-03-2018 SMD44_RS32355 58ca132c6c7fcedd25cb7167175dba2e 344 Gene3D G3DSA:2.120.10.70 5 298 2.3E-34 T 28-03-2018 SMD44_RS23165 ed81f5b4bed1e07ba70798c973418479 156 SUPERFAMILY SSF55298 5 153 1.73E-55 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS23165 ed81f5b4bed1e07ba70798c973418479 156 Gene3D G3DSA:3.30.1330.40 3 154 7.2E-31 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS23165 ed81f5b4bed1e07ba70798c973418479 156 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 152 8.5E-34 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS01825 ef9a42adf0fc4008b9a2310127f096de 535 Gene3D G3DSA:1.10.10.60 426 498 3.5E-5 T 28-03-2018 SMD44_RS01825 ef9a42adf0fc4008b9a2310127f096de 535 Pfam PF13556 PucR C-terminal helix-turn-helix domain 461 517 4.6E-19 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS22390 617c732377d7e4b9e876fdda484ec2c7 389 Gene3D G3DSA:1.10.150.130 65 173 1.3E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal SMD44_RS22390 617c732377d7e4b9e876fdda484ec2c7 389 Gene3D G3DSA:1.10.443.10 174 360 5.5E-32 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS22390 617c732377d7e4b9e876fdda484ec2c7 389 Pfam PF00589 Phage integrase family 191 352 2.4E-8 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS22390 617c732377d7e4b9e876fdda484ec2c7 389 SUPERFAMILY SSF56349 71 359 4.71E-49 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD44_RS29915 8e82f1c475825c421652801902516163 174 Gene3D G3DSA:3.30.70.1150 89 161 5.7E-30 T 28-03-2018 SMD44_RS29915 8e82f1c475825c421652801902516163 174 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 3.0E-34 T 28-03-2018 SMD44_RS29915 8e82f1c475825c421652801902516163 174 Gene3D G3DSA:3.30.70.260 1 88 4.4E-24 T 28-03-2018 SMD44_RS29915 8e82f1c475825c421652801902516163 174 SUPERFAMILY SSF55021 81 161 4.25E-26 T 28-03-2018 SMD44_RS29915 8e82f1c475825c421652801902516163 174 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 2.9E-61 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMD44_RS29915 8e82f1c475825c421652801902516163 174 SUPERFAMILY SSF55021 3 75 3.49E-22 T 28-03-2018 SMD44_RS29915 8e82f1c475825c421652801902516163 174 Pfam PF01842 ACT domain 4 69 3.2E-16 T 28-03-2018 IPR002912 ACT domain SMD44_RS29915 8e82f1c475825c421652801902516163 174 Pfam PF10369 Small subunit of acetolactate synthase 85 158 8.2E-29 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMD44_RS33520 348d5af73b47b4af7c570bcd9167d13a 540 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 23 539 5.0E-252 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMD44_RS33520 348d5af73b47b4af7c570bcd9167d13a 540 Gene3D G3DSA:3.20.20.360 78 420 1.4E-109 T 28-03-2018 SMD44_RS33520 348d5af73b47b4af7c570bcd9167d13a 540 Gene3D G3DSA:1.20.1220.12 421 539 3.5E-42 T 28-03-2018 SMD44_RS33520 348d5af73b47b4af7c570bcd9167d13a 540 PIRSF PIRSF001363 3 540 5.7E-239 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMD44_RS33520 348d5af73b47b4af7c570bcd9167d13a 540 ProSitePatterns PS00510 Malate synthase signature. 270 285 - T 28-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMD44_RS33520 348d5af73b47b4af7c570bcd9167d13a 540 Pfam PF01274 Malate synthase 18 539 1.4E-203 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMD44_RS33520 348d5af73b47b4af7c570bcd9167d13a 540 SUPERFAMILY SSF51645 18 539 6.93E-182 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMD44_RS19405 edc400ad18f81ae8465be669dceedcd3 206 Pfam PF01865 Protein of unknown function DUF47 7 203 8.9E-30 T 28-03-2018 IPR018445 Putative phosphate transport regulator SMD44_RS19405 edc400ad18f81ae8465be669dceedcd3 206 Gene3D G3DSA:1.20.58.220 101 205 1.2E-6 T 28-03-2018 SMD44_RS19405 edc400ad18f81ae8465be669dceedcd3 206 SUPERFAMILY SSF109755 43 199 1.23E-5 T 28-03-2018 SMD44_RS17240 6043f1131f6bad1688adb6fb74596cb6 270 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 10 269 2.6E-73 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SMD44_RS17240 6043f1131f6bad1688adb6fb74596cb6 270 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 11 268 1.8E-72 T 28-03-2018 SMD44_RS17240 6043f1131f6bad1688adb6fb74596cb6 270 Gene3D G3DSA:3.60.10.10 7 270 2.3E-50 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS17240 6043f1131f6bad1688adb6fb74596cb6 270 SUPERFAMILY SSF56219 9 269 4.19E-71 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS17240 6043f1131f6bad1688adb6fb74596cb6 270 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 13 262 9.6E-20 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS16950 84e341d825a90419de4607bb8a5f6fd7 196 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 94 1.0E-34 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD44_RS16950 84e341d825a90419de4607bb8a5f6fd7 196 Pfam PF01386 Ribosomal L25p family 6 91 6.5E-23 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD44_RS16950 84e341d825a90419de4607bb8a5f6fd7 196 SUPERFAMILY SSF50715 4 185 1.59E-46 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD44_RS16950 84e341d825a90419de4607bb8a5f6fd7 196 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 180 26.057 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD44_RS16950 84e341d825a90419de4607bb8a5f6fd7 196 Gene3D G3DSA:2.170.120.20 98 184 2.4E-21 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain SMD44_RS16950 84e341d825a90419de4607bb8a5f6fd7 196 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 179 1.7E-18 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain SMD44_RS16950 84e341d825a90419de4607bb8a5f6fd7 196 Gene3D G3DSA:2.40.240.10 3 93 5.7E-26 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD44_RS16950 84e341d825a90419de4607bb8a5f6fd7 196 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 177 1.2E-43 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD44_RS18400 5e58b7cc8ca4910bf1c5153339507e4e 423 SUPERFAMILY SSF56601 66 404 1.29E-67 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS18400 5e58b7cc8ca4910bf1c5153339507e4e 423 Gene3D G3DSA:3.40.710.10 59 418 5.5E-71 T 28-03-2018 SMD44_RS18400 5e58b7cc8ca4910bf1c5153339507e4e 423 Pfam PF00144 Beta-lactamase 69 396 8.2E-58 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS37215 93f0c730d70db5810651f0f28a49944f 119 Pfam PF05656 Protein of unknown function (DUF805) 11 110 8.9E-31 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 SMD44_RS09570 e8b2bbd509c084de5590ef2188e5ec96 378 Pfam PF00326 Prolyl oligopeptidase family 205 374 1.3E-5 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD44_RS09570 e8b2bbd509c084de5590ef2188e5ec96 378 Gene3D G3DSA:3.40.50.1820 132 377 1.1E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS09570 e8b2bbd509c084de5590ef2188e5ec96 378 SUPERFAMILY SSF53474 147 376 6.81E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS03280 63dd979ae32df39a09277dff6fad8172 191 SUPERFAMILY SSF51905 54 159 1.73E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03280 63dd979ae32df39a09277dff6fad8172 191 Gene3D G3DSA:3.50.50.60 4 100 8.6E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03280 63dd979ae32df39a09277dff6fad8172 191 Pfam PF08491 Squalene epoxidase 64 99 3.5E-5 T 28-03-2018 IPR013698 Squalene epoxidase GO:0004506|GO:0016021|GO:0050660|GO:0055114 KEGG: 00100+1.14.14.17|KEGG: 00909+1.14.14.17|MetaCyc: PWY-5670|MetaCyc: PWY-6098|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMD44_RS31185 9a235858bc0467faaeb009adaf60a0a1 228 Pfam PF03591 AzlC protein 2 135 1.1E-27 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease SMD44_RS03800 38c7d3dbd0cecf00b6191a2fae77dd01 199 Pfam PF10400 Virulence activator alpha C-term 92 180 2.8E-17 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal SMD44_RS03800 38c7d3dbd0cecf00b6191a2fae77dd01 199 Gene3D G3DSA:1.10.10.10 1 89 2.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03800 38c7d3dbd0cecf00b6191a2fae77dd01 199 SUPERFAMILY SSF46785 3 180 5.37E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS03800 38c7d3dbd0cecf00b6191a2fae77dd01 199 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 3.1E-11 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS29325 a93e86dff95f2c3ae6465d85e951fd94 410 Pfam PF00144 Beta-lactamase 18 387 9.4E-58 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS29325 a93e86dff95f2c3ae6465d85e951fd94 410 Gene3D G3DSA:3.40.710.10 2 410 4.2E-86 T 28-03-2018 SMD44_RS29325 a93e86dff95f2c3ae6465d85e951fd94 410 SUPERFAMILY SSF56601 12 401 3.81E-81 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS41015 4a76f58cc59e7c08cfa925b52f3ff8fa 124 Pfam PF02615 Malate/L-lactate dehydrogenase 1 102 2.3E-15 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 SMD44_RS41015 4a76f58cc59e7c08cfa925b52f3ff8fa 124 SUPERFAMILY SSF89733 1 112 9.55E-17 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 SMD44_RS41015 4a76f58cc59e7c08cfa925b52f3ff8fa 124 Gene3D G3DSA:3.30.1370.60 1 76 5.3E-10 T 28-03-2018 SMD44_RS22045 13983f7294a186048b44be8b9bd1196c 206 SUPERFAMILY SSF160387 88 203 2.88E-23 T 28-03-2018 SMD44_RS22045 13983f7294a186048b44be8b9bd1196c 206 Pfam PF03243 Alkylmercury lyase 86 203 1.9E-24 T 28-03-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 SMD44_RS36295 e6b22c0616acbe710491aef71ff36a80 469 Pfam PF00027 Cyclic nucleotide-binding domain 104 190 2.7E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS36295 e6b22c0616acbe710491aef71ff36a80 469 SUPERFAMILY SSF51206 79 194 2.23E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like SMD44_RS36295 e6b22c0616acbe710491aef71ff36a80 469 Gene3D G3DSA:2.60.120.10 80 205 2.3E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS36295 e6b22c0616acbe710491aef71ff36a80 469 SMART SM00100 85 206 9.7E-10 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain SMD44_RS13835 d3df0aef229719ba62962377796a8f84 629 Gene3D G3DSA:3.30.300.30 488 625 4.8E-14 T 28-03-2018 SMD44_RS13835 d3df0aef229719ba62962377796a8f84 629 SUPERFAMILY SSF56801 363 625 3.01E-121 T 28-03-2018 SMD44_RS13835 d3df0aef229719ba62962377796a8f84 629 SUPERFAMILY SSF56801 8 306 3.01E-121 T 28-03-2018 SMD44_RS13835 d3df0aef229719ba62962377796a8f84 629 Gene3D G3DSA:2.30.38.10 414 486 3.2E-23 T 28-03-2018 SMD44_RS13835 d3df0aef229719ba62962377796a8f84 629 Pfam PF00501 AMP-binding enzyme 20 493 2.7E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS13835 d3df0aef229719ba62962377796a8f84 629 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 28-03-2018 IPR020845 AMP-binding, conserved site SMD44_RS13835 d3df0aef229719ba62962377796a8f84 629 Gene3D G3DSA:3.40.50.980 12 208 1.0E-40 T 28-03-2018 SMD44_RS13835 d3df0aef229719ba62962377796a8f84 629 Gene3D G3DSA:3.40.50.980 209 413 7.9E-36 T 28-03-2018 SMD44_RS32945 d691356fb3445961a6beb65838431615 177 Gene3D G3DSA:2.60.40.230 44 177 1.3E-26 T 28-03-2018 SMD44_RS32945 d691356fb3445961a6beb65838431615 177 SUPERFAMILY SSF49319 52 177 3.6E-16 T 28-03-2018 IPR027273 Neocarzinostatin-like SMD44_RS38140 eac97e09e7a35f04cd11ce50a3c6af59 143 Pfam PF01374 Glycosyl hydrolase family 46 6 131 1.1E-27 T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMD44_RS38140 eac97e09e7a35f04cd11ce50a3c6af59 143 Gene3D G3DSA:1.20.141.10 1 138 1.5E-34 T 28-03-2018 SMD44_RS38140 eac97e09e7a35f04cd11ce50a3c6af59 143 SUPERFAMILY SSF53955 6 142 2.0E-26 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS17675 312a69d16440e9a3f715694098b32cea 365 SUPERFAMILY SSF101478 9 125 2.62E-51 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS17675 312a69d16440e9a3f715694098b32cea 365 SUPERFAMILY SSF101478 153 340 2.62E-51 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS17675 312a69d16440e9a3f715694098b32cea 365 Pfam PF03747 ADP-ribosylglycohydrolase 16 319 3.0E-50 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS17675 312a69d16440e9a3f715694098b32cea 365 Gene3D G3DSA:1.10.4080.10 2 344 1.1E-66 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS38325 e8bfbe2758c0e08bbd840a719a459864 179 Pfam PF07883 Cupin domain 93 158 6.2E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS38325 e8bfbe2758c0e08bbd840a719a459864 179 SUPERFAMILY SSF51182 49 157 4.02E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS38325 e8bfbe2758c0e08bbd840a719a459864 179 Pfam PF01381 Helix-turn-helix 1 52 7.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS38325 e8bfbe2758c0e08bbd840a719a459864 179 SMART SM00530 1 52 1.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS38325 e8bfbe2758c0e08bbd840a719a459864 179 Gene3D G3DSA:1.10.260.40 1 50 3.6E-14 T 28-03-2018 SMD44_RS38325 e8bfbe2758c0e08bbd840a719a459864 179 SUPERFAMILY SSF47413 1 58 2.2E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS38325 e8bfbe2758c0e08bbd840a719a459864 179 Gene3D G3DSA:2.60.120.10 51 173 4.0E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS29960 46f2e0a8882e27c1b989df31b418616c 543 Pfam PF00171 Aldehyde dehydrogenase family 56 526 2.0E-102 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS29960 46f2e0a8882e27c1b989df31b418616c 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS29960 46f2e0a8882e27c1b989df31b418616c 543 SUPERFAMILY SSF53720 8 527 4.84E-121 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS29960 46f2e0a8882e27c1b989df31b418616c 543 Gene3D G3DSA:3.40.309.10 312 506 3.5E-44 T 28-03-2018 SMD44_RS29960 46f2e0a8882e27c1b989df31b418616c 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 542 5.9E-239 T 28-03-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 SMD44_RS29960 46f2e0a8882e27c1b989df31b418616c 543 Gene3D G3DSA:3.40.605.10 36 311 2.8E-65 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS22825 9e8e1d427e432af90f288a726c5523cd 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 7.9E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS30390 b4b55af97b8e7cd9cb0be3d5df912920 67 Gene3D G3DSA:1.20.5.400 15 63 4.7E-4 T 28-03-2018 SMD44_RS20845 941a6e3d98c0d30e955e8d1691f9bacc 468 SUPERFAMILY SSF53300 253 444 1.31E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS20845 941a6e3d98c0d30e955e8d1691f9bacc 468 Pfam PF10138 vWA found in TerF C terminus 251 468 2.5E-85 T 28-03-2018 IPR019303 vWA found in TerF C terminus SMD44_RS20845 941a6e3d98c0d30e955e8d1691f9bacc 468 Pfam PF02342 TerD domain 4 171 7.2E-42 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS20845 941a6e3d98c0d30e955e8d1691f9bacc 468 SMART SM00327 251 441 6.2E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS20845 941a6e3d98c0d30e955e8d1691f9bacc 468 Gene3D G3DSA:2.60.60.30 15 170 5.0E-44 T 28-03-2018 SMD44_RS20845 941a6e3d98c0d30e955e8d1691f9bacc 468 Gene3D G3DSA:3.40.50.410 226 442 3.6E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS29305 cae929326753e664c358e4e5aa7ffd3c 145 SUPERFAMILY SSF55874 41 143 2.69E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29305 cae929326753e664c358e4e5aa7ffd3c 145 Pfam PF13581 Histidine kinase-like ATPase domain 49 140 3.4E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS29305 cae929326753e664c358e4e5aa7ffd3c 145 Gene3D G3DSA:3.30.565.10 14 145 1.0E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS43415 97f10c77278e127f9de8ce1ff1dde836 371 Pfam PF12642 Conjugative transposon protein TcpC 105 329 8.9E-24 T 28-03-2018 IPR024735 Conjugative transposon protein TcpC SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 PIRSF PIRSF005962 22 424 3.4E-101 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 SUPERFAMILY SSF53187 24 215 7.61E-78 T 28-03-2018 SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 SUPERFAMILY SSF53187 318 422 7.61E-78 T 28-03-2018 SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 Pfam PF01546 Peptidase family M20/M25/M40 89 377 5.6E-25 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 SUPERFAMILY SSF55031 202 310 1.7E-25 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 Pfam PF07687 Peptidase dimerisation domain 204 295 6.5E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 Gene3D G3DSA:3.40.630.10 15 255 6.4E-48 T 28-03-2018 SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 Gene3D G3DSA:3.40.630.10 263 426 2.8E-16 T 28-03-2018 SMD44_RS03490 c890125dae9b127dfdff196882fe9445 426 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 33 378 3.6E-89 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 SMD44_RS29040 ec39a52599d5a184bb5fc3fc3d88e2c9 272 Pfam PF03413 Peptidase propeptide and YPEB domain 216 267 9.5E-4 T 28-03-2018 IPR025711 PepSY domain SMD44_RS29040 ec39a52599d5a184bb5fc3fc3d88e2c9 272 Pfam PF03413 Peptidase propeptide and YPEB domain 124 183 1.1E-9 T 28-03-2018 IPR025711 PepSY domain SMD44_RS29040 ec39a52599d5a184bb5fc3fc3d88e2c9 272 Gene3D G3DSA:3.10.450.40 124 185 4.5E-14 T 28-03-2018 SMD44_RS29040 ec39a52599d5a184bb5fc3fc3d88e2c9 272 Gene3D G3DSA:3.10.450.40 210 269 1.4E-6 T 28-03-2018 SMD44_RS19840 26cbb0c09814359d3c91f39ec94ea27a 389 SUPERFAMILY SSF55874 238 364 2.75E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19840 26cbb0c09814359d3c91f39ec94ea27a 389 Gene3D G3DSA:3.30.565.10 229 372 3.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS19840 26cbb0c09814359d3c91f39ec94ea27a 389 Pfam PF07730 Histidine kinase 164 229 2.9E-5 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS19840 26cbb0c09814359d3c91f39ec94ea27a 389 SMART SM00387 273 366 6.4E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41480 445a9380bab7cfd99691a8ad3e535ad5 91 Gene3D G3DSA:3.20.20.70 4 91 1.5E-18 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS41480 445a9380bab7cfd99691a8ad3e535ad5 91 Pfam PF13353 4Fe-4S single cluster domain 9 85 7.8E-5 T 28-03-2018 SMD44_RS41480 445a9380bab7cfd99691a8ad3e535ad5 91 Pfam PF04055 Radical SAM superfamily 15 90 3.5E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS41480 445a9380bab7cfd99691a8ad3e535ad5 91 SUPERFAMILY SSF102114 7 91 1.57E-22 T 28-03-2018 SMD44_RS28930 667dde309d957ccedaa8473f70d6bacf 195 SUPERFAMILY SSF89028 6 190 3.92E-52 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMD44_RS28930 667dde309d957ccedaa8473f70d6bacf 195 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 189 2.0E-66 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMD44_RS28930 667dde309d957ccedaa8473f70d6bacf 195 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 187 2.1E-45 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMD44_RS28930 667dde309d957ccedaa8473f70d6bacf 195 Pfam PF01923 Cobalamin adenosyltransferase 7 179 2.0E-51 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMD44_RS28930 667dde309d957ccedaa8473f70d6bacf 195 Gene3D G3DSA:1.20.1200.10 16 195 2.2E-51 T 28-03-2018 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 SUPERFAMILY SSF51905 3 170 2.93E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 SUPERFAMILY SSF51905 264 351 2.93E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.6E-27 T 28-03-2018 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 2.6E-27 T 28-03-2018 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 2.6E-27 T 28-03-2018 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 328 2.6E-27 T 28-03-2018 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 2.6E-27 T 28-03-2018 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 Pfam PF01494 FAD binding domain 3 335 4.6E-40 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 Gene3D G3DSA:3.50.50.60 2 152 4.4E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS31250 0ee6e8443dc9dfde83e30df9e6b64030 596 Gene3D G3DSA:3.30.9.10 153 358 7.3E-32 T 28-03-2018 SMD44_RS09575 21b81f0c30dd087376314394f89f3238 278 SUPERFAMILY SSF53639 17 227 1.84E-62 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMD44_RS09575 21b81f0c30dd087376314394f89f3238 278 Gene3D G3DSA:3.40.225.10 2 227 6.0E-62 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMD44_RS09575 21b81f0c30dd087376314394f89f3238 278 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 194 8.5E-49 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMD44_RS09575 21b81f0c30dd087376314394f89f3238 278 SMART SM01007 22 195 5.5E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMD44_RS09575 21b81f0c30dd087376314394f89f3238 278 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 57 - T 28-03-2018 IPR010916 TonB box, conserved site SMD44_RS27255 10f9fa7263b00d78f5bcaa80518ce653 207 SUPERFAMILY SSF81995 2 64 1.31E-6 T 28-03-2018 SMD44_RS41180 d2c09386faba05b29eec01e886653591 269 SUPERFAMILY SSF51735 6 265 2.43E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS41180 d2c09386faba05b29eec01e886653591 269 Gene3D G3DSA:3.40.50.720 2 268 7.6E-39 T 28-03-2018 SMD44_RS41180 d2c09386faba05b29eec01e886653591 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 264 7.7E-43 T 28-03-2018 SMD44_RS41180 d2c09386faba05b29eec01e886653591 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41180 d2c09386faba05b29eec01e886653591 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 1.9E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41180 d2c09386faba05b29eec01e886653591 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 1.9E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS41180 d2c09386faba05b29eec01e886653591 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 1.9E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS20225 ac55e4b1326bc7e4b654dc0eb14f3e1d 603 SUPERFAMILY SSF53067 6 195 1.9E-12 T 28-03-2018 SMD44_RS20225 ac55e4b1326bc7e4b654dc0eb14f3e1d 603 SUPERFAMILY SSF53067 216 424 1.3E-15 T 28-03-2018 SMD44_RS20225 ac55e4b1326bc7e4b654dc0eb14f3e1d 603 Gene3D G3DSA:3.30.420.40 4 225 7.6E-26 T 28-03-2018 SMD44_RS20225 ac55e4b1326bc7e4b654dc0eb14f3e1d 603 Gene3D G3DSA:3.30.420.40 226 404 5.8E-14 T 28-03-2018 SMD44_RS32975 fcabc8643da0270ada3a1e6b47ed47cb 320 Gene3D G3DSA:3.60.40.10 41 318 7.2E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS32975 fcabc8643da0270ada3a1e6b47ed47cb 320 Pfam PF13672 Protein phosphatase 2C 52 298 5.5E-31 T 28-03-2018 SMD44_RS10265 19c01723e8ac3786f2cc1dcfdafe575c 468 SUPERFAMILY SSF103473 23 419 1.16E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS10265 19c01723e8ac3786f2cc1dcfdafe575c 468 Gene3D G3DSA:1.20.1250.20 238 430 1.4E-23 T 28-03-2018 SMD44_RS10265 19c01723e8ac3786f2cc1dcfdafe575c 468 Pfam PF07690 Major Facilitator Superfamily 250 429 6.2E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS10265 19c01723e8ac3786f2cc1dcfdafe575c 468 Gene3D G3DSA:1.20.1250.20 16 220 8.2E-17 T 28-03-2018 SMD44_RS31225 7f9a88699db6e4c76363fce56e70424c 253 Gene3D G3DSA:1.10.10.10 190 240 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31225 7f9a88699db6e4c76363fce56e70424c 253 Hamap MF_01114 Regulatory protein RecX [recX]. 88 241 15.673 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 SMD44_RS31225 7f9a88699db6e4c76363fce56e70424c 253 Gene3D G3DSA:1.10.10.10 84 139 6.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31225 7f9a88699db6e4c76363fce56e70424c 253 Pfam PF02631 RecX family 116 236 1.7E-28 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 SMD44_RS31225 7f9a88699db6e4c76363fce56e70424c 253 Gene3D G3DSA:1.10.10.10 141 185 1.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS28580 9273fdf1868ad3c96c46e05e35de9512 257 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 36 63 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SMD44_RS28580 9273fdf1868ad3c96c46e05e35de9512 257 SMART SM00650 21 181 4.7E-54 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SMD44_RS28580 9273fdf1868ad3c96c46e05e35de9512 257 Pfam PF00398 Ribosomal RNA adenine dimethylase 5 215 1.6E-26 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SMD44_RS28580 9273fdf1868ad3c96c46e05e35de9512 257 Gene3D G3DSA:3.40.50.150 1 198 8.2E-29 T 28-03-2018 SMD44_RS28580 9273fdf1868ad3c96c46e05e35de9512 257 SUPERFAMILY SSF53335 13 253 1.34E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS15810 9cef43a6a048c37e5b23239929be1ed4 574 Pfam PF06259 Alpha/beta hydrolase 335 503 6.8E-30 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 SMD44_RS10975 45f2a41a4f120c5c95a4ad0a964d405b 63 Pfam PF06348 Protein of unknown function (DUF1059) 4 57 2.8E-10 T 28-03-2018 IPR009409 Protein of unknown function DUF1059 SMD44_RS05495 e9454a411a7086d55589dcf7c3c94f12 492 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD44_RS05495 e9454a411a7086d55589dcf7c3c94f12 492 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 42 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD44_RS05495 e9454a411a7086d55589dcf7c3c94f12 492 SUPERFAMILY SSF56112 8 280 1.56E-67 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS05495 e9454a411a7086d55589dcf7c3c94f12 492 Gene3D G3DSA:1.10.510.10 99 283 3.0E-46 T 28-03-2018 SMD44_RS05495 e9454a411a7086d55589dcf7c3c94f12 492 SMART SM00220 12 273 2.3E-61 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS05495 e9454a411a7086d55589dcf7c3c94f12 492 Gene3D G3DSA:3.40.1000.10 356 490 1.4E-22 T 28-03-2018 SMD44_RS05495 e9454a411a7086d55589dcf7c3c94f12 492 Pfam PF00069 Protein kinase domain 12 262 1.5E-46 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS05495 e9454a411a7086d55589dcf7c3c94f12 492 Gene3D G3DSA:3.30.200.20 7 98 3.3E-21 T 28-03-2018 SMD44_RS43025 aa8bbd29fa68a1fddafc3fab263bb888 210 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 40 179 3.7E-10 T 28-03-2018 IPR013382 CRISPR-associated protein Cse2 SMD44_RS03040 489e3ee1b7c6e9cb05508e0ff9692ce3 240 Gene3D G3DSA:3.40.50.80 115 240 1.6E-34 T 28-03-2018 SMD44_RS03040 489e3ee1b7c6e9cb05508e0ff9692ce3 240 SUPERFAMILY SSF63380 10 107 1.76E-12 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD44_RS03040 489e3ee1b7c6e9cb05508e0ff9692ce3 240 Pfam PF04954 Siderophore-interacting protein 123 238 5.6E-21 T 28-03-2018 IPR007037 Siderophore-interacting protein SMD44_RS03040 489e3ee1b7c6e9cb05508e0ff9692ce3 240 Pfam PF08021 Siderophore-interacting FAD-binding domain 30 106 1.0E-10 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SMD44_RS03040 489e3ee1b7c6e9cb05508e0ff9692ce3 240 Gene3D G3DSA:2.40.30.10 13 112 6.8E-21 T 28-03-2018 SMD44_RS31015 9578639748b03d74215d4e5d20e27d82 111 Pfam PF04149 Domain of unknown function (DUF397) 43 92 1.3E-7 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS32735 bc68fc0fc7406c6368fab0974bffeabd 431 SUPERFAMILY SSF53850 43 420 1.78E-65 T 28-03-2018 SMD44_RS32735 bc68fc0fc7406c6368fab0974bffeabd 431 Pfam PF01547 Bacterial extracellular solute-binding protein 52 338 5.1E-41 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS32735 bc68fc0fc7406c6368fab0974bffeabd 431 Gene3D G3DSA:3.40.190.10 19 195 2.5E-36 T 28-03-2018 SMD44_RS32735 bc68fc0fc7406c6368fab0974bffeabd 431 Gene3D G3DSA:3.40.190.10 196 382 3.6E-10 T 28-03-2018 SMD44_RS33535 50bb1536c1ee5ed8848d0d362c232211 266 Pfam PF01614 Bacterial transcriptional regulator 135 257 7.5E-31 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMD44_RS33535 50bb1536c1ee5ed8848d0d362c232211 266 SUPERFAMILY SSF46785 20 90 3.96E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33535 50bb1536c1ee5ed8848d0d362c232211 266 SUPERFAMILY SSF55781 77 259 8.5E-50 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS33535 50bb1536c1ee5ed8848d0d362c232211 266 Pfam PF09339 IclR helix-turn-helix domain 22 73 6.3E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS33535 50bb1536c1ee5ed8848d0d362c232211 266 SMART SM00346 20 107 3.8E-22 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD44_RS33535 50bb1536c1ee5ed8848d0d362c232211 266 Gene3D G3DSA:3.30.450.40 89 264 2.1E-52 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS33535 50bb1536c1ee5ed8848d0d362c232211 266 Gene3D G3DSA:1.10.10.10 2 80 2.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18980 a9cba2326a3a3af227148eef63e8ceb7 577 Pfam PF07681 DoxX 239 340 3.7E-11 T 28-03-2018 IPR032808 DoxX family SMD44_RS13565 5a7163cc2f27c6e135dae715b3ae2ab7 249 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 206 1.7E-34 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMD44_RS13565 5a7163cc2f27c6e135dae715b3ae2ab7 249 Gene3D G3DSA:2.40.50.140 1 87 2.6E-28 T 28-03-2018 SMD44_RS13565 5a7163cc2f27c6e135dae715b3ae2ab7 249 SUPERFAMILY SSF57863 88 238 8.63E-38 T 28-03-2018 SMD44_RS13565 5a7163cc2f27c6e135dae715b3ae2ab7 249 Pfam PF02565 Recombination protein O C terminal 91 244 1.5E-31 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMD44_RS13565 5a7163cc2f27c6e135dae715b3ae2ab7 249 Pfam PF11967 Recombination protein O N terminal 1 85 4.8E-28 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal SMD44_RS13565 5a7163cc2f27c6e135dae715b3ae2ab7 249 SUPERFAMILY SSF50249 1 85 1.64E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS13565 5a7163cc2f27c6e135dae715b3ae2ab7 249 Hamap MF_00201 DNA repair protein RecO [recO]. 2 249 26.537 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMD44_RS01275 dfdcba22d40ae22625b034ec18c29505 384 Pfam PF00144 Beta-lactamase 56 374 2.1E-63 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS01275 dfdcba22d40ae22625b034ec18c29505 384 Gene3D G3DSA:3.40.710.10 33 383 3.4E-73 T 28-03-2018 SMD44_RS01275 dfdcba22d40ae22625b034ec18c29505 384 SUPERFAMILY SSF56601 49 365 4.14E-75 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS38860 3dd60c39c2e8344f5034d373e18c7d3a 421 Gene3D G3DSA:3.40.50.2000 32 214 9.7E-16 T 28-03-2018 SMD44_RS38860 3dd60c39c2e8344f5034d373e18c7d3a 421 Gene3D G3DSA:3.40.50.2000 215 383 3.2E-33 T 28-03-2018 SMD44_RS38860 3dd60c39c2e8344f5034d373e18c7d3a 421 Pfam PF13692 Glycosyl transferases group 1 219 365 3.7E-24 T 28-03-2018 SMD44_RS38860 3dd60c39c2e8344f5034d373e18c7d3a 421 SUPERFAMILY SSF53756 28 397 8.52E-57 T 28-03-2018 SMD44_RS38860 3dd60c39c2e8344f5034d373e18c7d3a 421 Pfam PF13579 Glycosyl transferase 4-like domain 28 195 7.1E-18 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS34780 39c6739465bfc6bdf0dca99c072c1d39 354 Gene3D G3DSA:3.20.20.150 63 352 1.8E-37 T 28-03-2018 SMD44_RS34780 39c6739465bfc6bdf0dca99c072c1d39 354 Pfam PF01261 Xylose isomerase-like TIM barrel 87 302 3.8E-24 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS34780 39c6739465bfc6bdf0dca99c072c1d39 354 SUPERFAMILY SSF51658 81 348 1.14E-31 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS05335 9fa60f41d1fa3cbfff8ade8031a5e0b6 152 Pfam PF12802 MarR family 37 97 1.6E-10 T 28-03-2018 SMD44_RS05335 9fa60f41d1fa3cbfff8ade8031a5e0b6 152 SMART SM00347 32 135 2.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS05335 9fa60f41d1fa3cbfff8ade8031a5e0b6 152 SUPERFAMILY SSF46785 5 150 8.06E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS05335 9fa60f41d1fa3cbfff8ade8031a5e0b6 152 Gene3D G3DSA:1.10.10.10 4 152 1.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 Pfam PF00072 Response regulator receiver domain 3 113 2.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 Pfam PF00672 HAMP domain 326 373 2.6E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 Gene3D G3DSA:1.10.287.130 369 423 3.4E-8 T 28-03-2018 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 Gene3D G3DSA:1.10.10.10 118 213 1.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 380 407 7.3E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 SMART SM00862 145 237 3.0E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 SMART SM00448 1 112 3.2E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 211 1.0E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 SUPERFAMILY SSF158472 327 374 3.53E-5 T 28-03-2018 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 SUPERFAMILY SSF52172 1 173 8.11E-35 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 SUPERFAMILY SSF47384 365 408 1.84E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 SMART SM00304 325 378 1.2E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD44_RS41365 597878d934c27901c6569c78e6a31f7f 432 Gene3D G3DSA:3.40.50.2300 1 117 2.2E-30 T 28-03-2018 SMD44_RS09020 9b6930fab59b41dcf9faf64eb0adeba3 214 SUPERFAMILY SSF54106 168 214 9.94E-10 T 28-03-2018 IPR018392 LysM domain SMD44_RS09020 9b6930fab59b41dcf9faf64eb0adeba3 214 Pfam PF01476 LysM domain 169 214 3.0E-13 T 28-03-2018 IPR018392 LysM domain SMD44_RS09020 9b6930fab59b41dcf9faf64eb0adeba3 214 SUPERFAMILY SSF53955 34 114 1.69E-31 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS09020 9b6930fab59b41dcf9faf64eb0adeba3 214 Pfam PF06737 Transglycosylase-like domain 34 109 1.8E-33 T 28-03-2018 IPR010618 Transglycosylase-like SMD44_RS09020 9b6930fab59b41dcf9faf64eb0adeba3 214 Gene3D G3DSA:1.10.530.10 16 116 9.7E-31 T 28-03-2018 SMD44_RS09020 9b6930fab59b41dcf9faf64eb0adeba3 214 SMART SM00257 168 214 3.4E-8 T 28-03-2018 IPR018392 LysM domain SMD44_RS09020 9b6930fab59b41dcf9faf64eb0adeba3 214 Gene3D G3DSA:3.10.350.10 166 214 2.1E-16 T 28-03-2018 SMD44_RS09915 4a710ba7b4676f97ad4bf902926572df 612 Gene3D G3DSA:2.40.50.200 22 130 0.0025 T 28-03-2018 SMD44_RS09915 4a710ba7b4676f97ad4bf902926572df 612 Gene3D G3DSA:3.60.10.10 309 611 5.2E-29 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS09915 4a710ba7b4676f97ad4bf902926572df 612 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 312 595 1.8E-6 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS09915 4a710ba7b4676f97ad4bf902926572df 612 SUPERFAMILY SSF56219 310 610 8.38E-26 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS29525 3b3817948cbdb90ad8c6db656804c58b 235 PIRSF PIRSF006648 2 234 4.1E-14 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS29525 3b3817948cbdb90ad8c6db656804c58b 235 Pfam PF01061 ABC-2 type transporter 3 200 8.5E-22 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS29525 3b3817948cbdb90ad8c6db656804c58b 235 PRINTS PR00164 ABC-2 type transport system membrane protein signature 162 181 3.5E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS29525 3b3817948cbdb90ad8c6db656804c58b 235 PRINTS PR00164 ABC-2 type transport system membrane protein signature 11 32 3.5E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS29525 3b3817948cbdb90ad8c6db656804c58b 235 PRINTS PR00164 ABC-2 type transport system membrane protein signature 125 149 3.5E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS42180 eb4320a0a229c02f151443c5e75ffbe1 270 SUPERFAMILY SSF56801 2 227 6.28E-42 T 28-03-2018 SMD44_RS42180 eb4320a0a229c02f151443c5e75ffbe1 270 Gene3D G3DSA:3.40.50.980 1 92 2.9E-16 T 28-03-2018 SMD44_RS42180 eb4320a0a229c02f151443c5e75ffbe1 270 Pfam PF00501 AMP-binding enzyme 3 196 2.1E-32 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS42180 eb4320a0a229c02f151443c5e75ffbe1 270 Gene3D G3DSA:2.30.38.10 93 190 3.2E-17 T 28-03-2018 SMD44_RS29660 41cf65aa8bd7d95125b085a2927550e3 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMD44_RS29660 41cf65aa8bd7d95125b085a2927550e3 125 Pfam PF01597 Glycine cleavage H-protein 7 122 2.0E-40 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate SMD44_RS29660 41cf65aa8bd7d95125b085a2927550e3 125 SUPERFAMILY SSF51230 4 123 8.23E-39 T 28-03-2018 IPR011053 Single hybrid motif SMD44_RS29660 41cf65aa8bd7d95125b085a2927550e3 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 121 1.2E-43 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 SMD44_RS29660 41cf65aa8bd7d95125b085a2927550e3 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 37.652 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 SMD44_RS29660 41cf65aa8bd7d95125b085a2927550e3 125 Gene3D G3DSA:2.40.50.100 5 125 3.9E-42 T 28-03-2018 SMD44_RS17220 6292b0127b5eac811264b9286433fe76 319 SUPERFAMILY SSF53474 11 296 8.93E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS17220 6292b0127b5eac811264b9286433fe76 319 Gene3D G3DSA:3.40.50.1820 5 301 6.0E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS17220 6292b0127b5eac811264b9286433fe76 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 2.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS17220 6292b0127b5eac811264b9286433fe76 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 243 257 2.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS17220 6292b0127b5eac811264b9286433fe76 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 2.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS17220 6292b0127b5eac811264b9286433fe76 319 Pfam PF12697 Alpha/beta hydrolase family 44 292 1.0E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS12865 da913f84c388e7b288780df8a963eb51 239 Gene3D G3DSA:3.40.50.150 78 220 2.4E-13 T 28-03-2018 SMD44_RS12865 da913f84c388e7b288780df8a963eb51 239 SUPERFAMILY SSF53335 27 169 1.36E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS12865 da913f84c388e7b288780df8a963eb51 239 Gene3D G3DSA:3.40.50.150 5 77 5.9E-6 T 28-03-2018 SMD44_RS12865 da913f84c388e7b288780df8a963eb51 239 Pfam PF08241 Methyltransferase domain 50 137 1.3E-15 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS37335 570acedec3a33061d4154ef1f674d681 312 Pfam PF03640 Secreted repeat of unknown function 260 301 5.0E-16 T 28-03-2018 IPR005297 Lipoprotein repeat SMD44_RS37335 570acedec3a33061d4154ef1f674d681 312 Pfam PF03640 Secreted repeat of unknown function 201 243 1.2E-16 T 28-03-2018 IPR005297 Lipoprotein repeat SMD44_RS37335 570acedec3a33061d4154ef1f674d681 312 Pfam PF03640 Secreted repeat of unknown function 67 108 1.0E-13 T 28-03-2018 IPR005297 Lipoprotein repeat SMD44_RS37335 570acedec3a33061d4154ef1f674d681 312 Pfam PF03640 Secreted repeat of unknown function 126 166 5.7E-17 T 28-03-2018 IPR005297 Lipoprotein repeat SMD44_RS16425 dbe8c52391841a1180cf9d83a3638027 1268 SUPERFAMILY SSF53448 153 302 3.7E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16425 dbe8c52391841a1180cf9d83a3638027 1268 SUPERFAMILY SSF53448 36 114 3.7E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16425 dbe8c52391841a1180cf9d83a3638027 1268 Gene3D G3DSA:3.90.550.10 10 313 3.3E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16425 dbe8c52391841a1180cf9d83a3638027 1268 Pfam PF13641 Glycosyltransferase like family 2 51 298 3.2E-15 T 28-03-2018 SMD44_RS34930 f6936686e829faba38401bca9cb512d1 285 Gene3D G3DSA:2.60.120.620 19 283 3.0E-34 T 28-03-2018 SMD44_RS34930 f6936686e829faba38401bca9cb512d1 285 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 39 257 1.5E-12 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMD44_RS34930 f6936686e829faba38401bca9cb512d1 285 SUPERFAMILY SSF51197 32 280 1.1E-35 T 28-03-2018 SMD44_RS03115 a51805519149e020057b638a8844c83e 386 Pfam PF13535 ATP-grasp domain 101 254 3.7E-15 T 28-03-2018 SMD44_RS03115 a51805519149e020057b638a8844c83e 386 Gene3D G3DSA:3.30.470.20 44 352 2.4E-18 T 28-03-2018 SMD44_RS03115 a51805519149e020057b638a8844c83e 386 SUPERFAMILY SSF56059 97 273 1.54E-24 T 28-03-2018 SMD44_RS35885 09ec658f8451c262c98e8412690ae3c4 185 Gene3D G3DSA:3.40.1360.10 76 185 1.3E-10 T 28-03-2018 SMD44_RS35885 09ec658f8451c262c98e8412690ae3c4 185 SUPERFAMILY SSF56731 67 183 1.31E-8 T 28-03-2018 SMD44_RS34840 4ae432732144d08fb846079555a8c549 127 Gene3D G3DSA:1.10.10.10 31 120 8.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS07545 05ff8bc27c40f95bb01b94181d708b04 148 SUPERFAMILY SSF55961 7 146 7.04E-20 T 28-03-2018 SMD44_RS07545 05ff8bc27c40f95bb01b94181d708b04 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 14 115 3.8E-11 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS07545 05ff8bc27c40f95bb01b94181d708b04 148 Gene3D G3DSA:3.30.530.20 4 148 1.9E-20 T 28-03-2018 IPR023393 START-like domain SMD44_RS31120 8ed37a7f9a3a7ffdd92f6ae02967f207 227 Pfam PF00072 Response regulator receiver domain 7 119 1.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31120 8ed37a7f9a3a7ffdd92f6ae02967f207 227 SMART SM00448 5 119 7.4E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31120 8ed37a7f9a3a7ffdd92f6ae02967f207 227 Gene3D G3DSA:3.40.50.2300 2 204 5.0E-39 T 28-03-2018 SMD44_RS31120 8ed37a7f9a3a7ffdd92f6ae02967f207 227 SUPERFAMILY SSF52172 3 145 1.57E-37 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 SUPERFAMILY SSF52172 6 136 2.28E-29 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 Pfam PF00072 Response regulator receiver domain 8 122 7.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 SMART SM00421 157 214 2.5E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 214 5.2E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 Gene3D G3DSA:3.40.50.2300 5 139 1.7E-33 T 28-03-2018 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 SUPERFAMILY SSF46894 154 219 1.05E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 SMART SM00448 6 121 3.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS32110 dc25967e97ccd98a7c3a70d51e69eee3 224 Gene3D G3DSA:1.10.10.10 140 219 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09205 785250e3ac19ed2ff54332ce83e85d8c 354 Pfam PF01497 Periplasmic binding protein 95 321 2.6E-17 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD44_RS09205 785250e3ac19ed2ff54332ce83e85d8c 354 SUPERFAMILY SSF53807 61 346 3.69E-29 T 28-03-2018 SMD44_RS09205 785250e3ac19ed2ff54332ce83e85d8c 354 Gene3D G3DSA:3.40.50.1980 52 186 5.4E-13 T 28-03-2018 SMD44_RS09205 785250e3ac19ed2ff54332ce83e85d8c 354 Gene3D G3DSA:3.40.50.1980 187 353 8.6E-22 T 28-03-2018 SMD44_RS01870 f4da5b993d865151134b2b7d08a43a85 270 Pfam PF08241 Methyltransferase domain 58 154 3.0E-16 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS01870 f4da5b993d865151134b2b7d08a43a85 270 SUPERFAMILY SSF53335 4 267 2.61E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS01870 f4da5b993d865151134b2b7d08a43a85 270 Gene3D G3DSA:3.40.50.150 11 270 5.1E-34 T 28-03-2018 SMD44_RS32585 c7307d5b3dcea5fb7ca62a179c4c05d6 178 Pfam PF01025 GrpE 41 157 1.3E-16 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD44_RS32585 c7307d5b3dcea5fb7ca62a179c4c05d6 178 SUPERFAMILY SSF51064 102 158 1.03E-8 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMD44_RS32585 c7307d5b3dcea5fb7ca62a179c4c05d6 178 Gene3D G3DSA:2.30.22.10 101 158 1.9E-17 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMD44_RS08800 7d88ea8d5b20ec58f8c24f4089cd3bc3 289 SUPERFAMILY SSF53474 54 243 2.26E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS08800 7d88ea8d5b20ec58f8c24f4089cd3bc3 289 Pfam PF01674 Lipase (class 2) 57 259 8.4E-16 T 28-03-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD44_RS08800 7d88ea8d5b20ec58f8c24f4089cd3bc3 289 Gene3D G3DSA:3.40.50.1820 19 287 1.9E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS12815 9d327710fbe7c169ddbdd7ade3959b0a 277 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 10 229 1.2E-30 T 28-03-2018 SMD44_RS29275 872d90d608dfa3366310b5775ae8b9ed 322 SMART SM00418 243 315 5.8E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS29275 872d90d608dfa3366310b5775ae8b9ed 322 Pfam PF12840 Helix-turn-helix domain 252 299 3.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29275 872d90d608dfa3366310b5775ae8b9ed 322 Gene3D G3DSA:1.10.10.10 112 321 4.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29275 872d90d608dfa3366310b5775ae8b9ed 322 SUPERFAMILY SSF46785 248 314 2.49E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09045 7ce64470aa9959bbea1653fb1dd6e674 231 Gene3D G3DSA:3.40.50.300 10 228 1.4E-43 T 28-03-2018 SMD44_RS09045 7ce64470aa9959bbea1653fb1dd6e674 231 Hamap MF_00238 Cytidylate kinase [cmk]. 12 228 30.949 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SMD44_RS09045 7ce64470aa9959bbea1653fb1dd6e674 231 TIGRFAM TIGR00017 cmk: cytidylate kinase 12 222 5.9E-61 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SMD44_RS09045 7ce64470aa9959bbea1653fb1dd6e674 231 SUPERFAMILY SSF52540 10 227 1.85E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09045 7ce64470aa9959bbea1653fb1dd6e674 231 Pfam PF02224 Cytidylate kinase 14 225 1.4E-64 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SMD44_RS12275 8e4d2a69629b40aafa41241a1ac0abd4 425 Gene3D G3DSA:3.30.565.10 277 399 1.8E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS12275 8e4d2a69629b40aafa41241a1ac0abd4 425 Pfam PF07730 Histidine kinase 212 279 2.2E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS12275 8e4d2a69629b40aafa41241a1ac0abd4 425 SUPERFAMILY SSF55874 293 396 2.15E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16975 c576badc72529cc0d9dc2ff52ad917e6 239 ProSitePatterns PS01081 TetR-type HTH domain signature. 61 91 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD44_RS16975 c576badc72529cc0d9dc2ff52ad917e6 239 Gene3D G3DSA:1.10.357.10 94 228 7.1E-17 T 28-03-2018 SMD44_RS16975 c576badc72529cc0d9dc2ff52ad917e6 239 SUPERFAMILY SSF48498 116 226 1.25E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS16975 c576badc72529cc0d9dc2ff52ad917e6 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 93 3.0E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS16975 c576badc72529cc0d9dc2ff52ad917e6 239 Gene3D G3DSA:1.10.10.60 6 93 3.9E-23 T 28-03-2018 SMD44_RS16975 c576badc72529cc0d9dc2ff52ad917e6 239 SUPERFAMILY SSF46689 35 113 2.41E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS16975 c576badc72529cc0d9dc2ff52ad917e6 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 62 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS16975 c576badc72529cc0d9dc2ff52ad917e6 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 70 93 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 422 1.9E-47 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 Pfam PF02056 Family 4 glycosyl hydrolase 4 179 4.3E-42 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 4.4E-38 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 4.4E-38 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 186 198 4.4E-38 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 4.4E-38 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 4.4E-38 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 4.4E-38 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 160 171 4.4E-38 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 SUPERFAMILY SSF51735 1 163 7.29E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 135 165 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 SUPERFAMILY SSF56327 164 442 1.54E-64 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD44_RS35040 fed5758c19bbfc965c0645ed3b30d54e 446 Gene3D G3DSA:3.90.1820.10 1 444 2.9E-132 T 28-03-2018 SMD44_RS20330 c3a6d6bb47b8609f5f461702f3385d03 122 SUPERFAMILY SSF54909 19 121 2.83E-31 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS20330 c3a6d6bb47b8609f5f461702f3385d03 122 Gene3D G3DSA:3.30.70.100 24 116 3.6E-23 T 28-03-2018 SMD44_RS40805 52f193b6bdec91de171aa8c61476f904 150 Gene3D G3DSA:3.40.630.30 2 79 2.2E-10 T 28-03-2018 SMD44_RS40805 52f193b6bdec91de171aa8c61476f904 150 SUPERFAMILY SSF55729 3 130 5.32E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS40805 52f193b6bdec91de171aa8c61476f904 150 Gene3D G3DSA:3.40.630.30 80 144 2.4E-12 T 28-03-2018 SMD44_RS40805 52f193b6bdec91de171aa8c61476f904 150 Pfam PF13673 Acetyltransferase (GNAT) domain 34 129 2.3E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS24985 4979c8863c701605bd59f4c1fa67d167 362 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 79 305 5.9E-60 T 28-03-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 SMD44_RS24985 4979c8863c701605bd59f4c1fa67d167 362 Pfam PF03837 RecT family 118 309 1.4E-50 T 28-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 SMD44_RS16480 4e3414fde89635671cd1edea15a22070 542 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 141 302 6.7E-36 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS16480 4e3414fde89635671cd1edea15a22070 542 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 410 502 3.4E-12 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD44_RS16480 4e3414fde89635671cd1edea15a22070 542 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 141 302 1.4E-38 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS34435 68ee79c2af8d66970b1ef6e61d887631 233 SUPERFAMILY SSF55781 23 158 1.41E-10 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS34435 68ee79c2af8d66970b1ef6e61d887631 233 Gene3D G3DSA:3.30.450.40 11 165 1.1E-11 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS34435 68ee79c2af8d66970b1ef6e61d887631 233 PIRSF PIRSF036625 11 227 2.0E-35 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD44_RS34435 68ee79c2af8d66970b1ef6e61d887631 233 SUPERFAMILY SSF52172 88 217 2.19E-11 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS34435 68ee79c2af8d66970b1ef6e61d887631 233 Pfam PF03861 ANTAR domain 165 217 7.2E-18 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS34435 68ee79c2af8d66970b1ef6e61d887631 233 Gene3D G3DSA:1.10.10.10 166 219 1.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS34435 68ee79c2af8d66970b1ef6e61d887631 233 SMART SM01012 162 217 5.3E-19 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 SMD44_RS43565 168f09655350f1103ce0a213d1a96da7 530 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 7 520 1.8E-119 T 28-03-2018 IPR013381 CRISPR-associated protein Cse1 SMD44_RS43565 168f09655350f1103ce0a213d1a96da7 530 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 7 466 1.2E-80 T 28-03-2018 IPR013381 CRISPR-associated protein Cse1 SMD44_RS18010 7869ab696de1cf880b8de234f5aad28f 488 Gene3D G3DSA:1.25.40.10 221 476 4.7E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS18010 7869ab696de1cf880b8de234f5aad28f 488 Gene3D G3DSA:1.10.260.40 18 104 9.7E-6 T 28-03-2018 SMD44_RS34725 6e058e41839f4d5f3278b1ed03da3b74 452 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 170 241 1.6E-10 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD44_RS34725 6e058e41839f4d5f3278b1ed03da3b74 452 SUPERFAMILY SSF55347 288 354 1.02E-34 T 28-03-2018 SMD44_RS34725 6e058e41839f4d5f3278b1ed03da3b74 452 SUPERFAMILY SSF55347 164 249 1.02E-34 T 28-03-2018 SMD44_RS34725 6e058e41839f4d5f3278b1ed03da3b74 452 Gene3D G3DSA:3.30.360.10 171 433 1.8E-54 T 28-03-2018 SMD44_RS34725 6e058e41839f4d5f3278b1ed03da3b74 452 Gene3D G3DSA:3.40.50.720 19 170 2.1E-39 T 28-03-2018 SMD44_RS34725 6e058e41839f4d5f3278b1ed03da3b74 452 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 30 153 9.6E-25 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD44_RS34725 6e058e41839f4d5f3278b1ed03da3b74 452 SUPERFAMILY SSF51735 26 190 1.88E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS32025 43222c182ab60ceaef277cac93d96b49 401 SUPERFAMILY SSF48208 9 323 7.82E-40 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS32025 43222c182ab60ceaef277cac93d96b49 401 SUPERFAMILY SSF48208 354 396 7.82E-40 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD44_RS32025 43222c182ab60ceaef277cac93d96b49 401 Gene3D G3DSA:1.50.10.10 6 400 1.4E-39 T 28-03-2018 SMD44_RS09460 df75cf9af9239e0c6d860c01de8c37c9 416 Gene3D G3DSA:3.20.20.140 14 384 4.6E-60 T 28-03-2018 SMD44_RS09460 df75cf9af9239e0c6d860c01de8c37c9 416 SUPERFAMILY SSF51556 13 373 1.69E-64 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS09460 df75cf9af9239e0c6d860c01de8c37c9 416 Pfam PF04909 Amidohydrolase 53 372 1.0E-43 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS03785 91fe91bb64e42ec20d8d675404c93a05 136 Gene3D G3DSA:3.40.50.510 3 135 3.3E-31 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMD44_RS03785 91fe91bb64e42ec20d8d675404c93a05 136 Pfam PF03610 PTS system fructose IIA component 9 123 3.2E-24 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMD44_RS03785 91fe91bb64e42ec20d8d675404c93a05 136 SUPERFAMILY SSF53062 8 133 1.12E-27 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMD44_RS22950 52f50b892a8c571b4862003e0c64f6a5 206 SUPERFAMILY SSF48498 81 180 1.38E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS22950 52f50b892a8c571b4862003e0c64f6a5 206 Gene3D G3DSA:1.10.357.10 61 189 3.0E-20 T 28-03-2018 SMD44_RS22950 52f50b892a8c571b4862003e0c64f6a5 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS22950 52f50b892a8c571b4862003e0c64f6a5 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS22950 52f50b892a8c571b4862003e0c64f6a5 206 Gene3D G3DSA:1.10.10.60 2 60 1.3E-18 T 28-03-2018 SMD44_RS22950 52f50b892a8c571b4862003e0c64f6a5 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 8.8E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS22950 52f50b892a8c571b4862003e0c64f6a5 206 SUPERFAMILY SSF46689 6 85 2.41E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS34180 4b59b84ef8ccdf152f70c26f2845f9c4 170 SUPERFAMILY SSF54637 2 148 1.7E-42 T 28-03-2018 IPR029069 HotDog domain SMD44_RS34180 4b59b84ef8ccdf152f70c26f2845f9c4 170 Gene3D G3DSA:3.10.129.10 1 150 6.8E-30 T 28-03-2018 SMD44_RS34180 4b59b84ef8ccdf152f70c26f2845f9c4 170 Pfam PF01575 MaoC like domain 12 125 3.7E-15 T 28-03-2018 IPR002539 MaoC-like domain SMD44_RS14855 63320b98ce8b5a4fbc7545d4f9b9907b 309 SUPERFAMILY SSF103481 201 285 1.7E-13 T 28-03-2018 SMD44_RS14855 63320b98ce8b5a4fbc7545d4f9b9907b 309 SUPERFAMILY SSF103481 39 134 1.57E-11 T 28-03-2018 SMD44_RS14855 63320b98ce8b5a4fbc7545d4f9b9907b 309 Pfam PF00892 EamA-like transporter family 6 130 4.6E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS14855 63320b98ce8b5a4fbc7545d4f9b9907b 309 Pfam PF00892 EamA-like transporter family 145 280 2.4E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 Pfam PF01341 Glycosyl hydrolases family 6 58 321 4.2E-81 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PIRSF PIRSF001100 9 341 9.0E-93 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 229 239 3.4E-38 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 113 126 3.4E-38 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 302 316 3.4E-38 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 73 92 3.4E-38 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 278 298 3.4E-38 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 259 272 3.4E-38 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 141 156 3.4E-38 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 198 211 3.4E-38 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 158 167 - T 28-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 118 134 - T 28-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 Gene3D G3DSA:3.20.20.40 49 339 3.9E-101 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS29115 cc3e7c6ccd4b22ad74bf14b41d769fd6 341 SUPERFAMILY SSF51989 49 340 3.79E-85 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD44_RS04160 2cef0df48032680d43c3fd787f263023 456 Gene3D G3DSA:3.40.50.1820 83 440 6.7E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS04160 2cef0df48032680d43c3fd787f263023 456 Pfam PF10605 3HB-oligomer hydrolase (3HBOH) 336 446 4.1E-7 T 28-03-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 SMD44_RS04160 2cef0df48032680d43c3fd787f263023 456 Pfam PF07519 Tannase and feruloyl esterase 113 219 1.2E-11 T 28-03-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 SMD44_RS04160 2cef0df48032680d43c3fd787f263023 456 SUPERFAMILY SSF53474 347 417 1.9E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS04160 2cef0df48032680d43c3fd787f263023 456 SUPERFAMILY SSF53474 127 242 1.9E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05815 942f060c982d347bfb8fa7bd7d4a3ae5 74 Pfam PF04149 Domain of unknown function (DUF397) 17 74 3.6E-20 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS38920 be53e413528dce827d9cbbc1930d125a 456 Gene3D G3DSA:1.25.20.10 11 267 4.1E-9 T 28-03-2018 SMD44_RS38920 be53e413528dce827d9cbbc1930d125a 456 SUPERFAMILY SSF48452 157 255 4.08E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS38920 be53e413528dce827d9cbbc1930d125a 456 Gene3D G3DSA:1.25.40.10 357 454 3.9E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS19025 15856c8c4d932e1f9b9812d42564fba9 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.0E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19025 15856c8c4d932e1f9b9812d42564fba9 226 SMART SM00862 148 224 6.0E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS19025 15856c8c4d932e1f9b9812d42564fba9 226 Pfam PF00072 Response regulator receiver domain 4 113 9.7E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS19025 15856c8c4d932e1f9b9812d42564fba9 226 Gene3D G3DSA:3.40.50.2300 1 118 1.3E-36 T 28-03-2018 SMD44_RS19025 15856c8c4d932e1f9b9812d42564fba9 226 SUPERFAMILY SSF52172 3 125 2.99E-41 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS19025 15856c8c4d932e1f9b9812d42564fba9 226 Gene3D G3DSA:1.10.10.10 119 226 3.0E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19025 15856c8c4d932e1f9b9812d42564fba9 226 SUPERFAMILY SSF46894 124 225 9.64E-32 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS19025 15856c8c4d932e1f9b9812d42564fba9 226 SMART SM00448 2 112 2.3E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS21290 7c54563c4001d8ad95ce0ab70cfb0405 239 Pfam PF01522 Polysaccharide deacetylase 50 183 1.8E-27 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS21290 7c54563c4001d8ad95ce0ab70cfb0405 239 Gene3D G3DSA:3.20.20.370 3 228 1.5E-44 T 28-03-2018 SMD44_RS21290 7c54563c4001d8ad95ce0ab70cfb0405 239 SUPERFAMILY SSF88713 13 185 1.33E-35 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS33920 21d6af262535a75d10ac670d510e823e 302 SMART SM00062 62 286 5.6E-56 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS33920 21d6af262535a75d10ac670d510e823e 302 Gene3D G3DSA:3.40.190.10 52 166 2.5E-23 T 28-03-2018 SMD44_RS33920 21d6af262535a75d10ac670d510e823e 302 Gene3D G3DSA:3.40.190.10 167 251 9.8E-22 T 28-03-2018 SMD44_RS33920 21d6af262535a75d10ac670d510e823e 302 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 280 4.0E-46 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD44_RS33920 21d6af262535a75d10ac670d510e823e 302 SUPERFAMILY SSF53850 52 280 1.6E-54 T 28-03-2018 SMD44_RS33920 21d6af262535a75d10ac670d510e823e 302 SUPERFAMILY SSF53850 5 22 1.6E-54 T 28-03-2018 SMD44_RS35090 ad054bf80d135fa19a587bcc39cd1eee 344 Gene3D G3DSA:3.40.1000.10 173 330 1.2E-14 T 28-03-2018 SMD44_RS35090 ad054bf80d135fa19a587bcc39cd1eee 344 Pfam PF10708 Protein of unknown function (DUF2510) 25 60 4.0E-9 T 28-03-2018 IPR018929 Domain of unknown function DUF2510 SMD44_RS16495 b5d77c6fb781afd47d8c3a63a6a61e88 148 Pfam PF12680 SnoaL-like domain 15 126 5.4E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS16495 b5d77c6fb781afd47d8c3a63a6a61e88 148 SUPERFAMILY SSF54427 9 130 2.66E-17 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS16495 b5d77c6fb781afd47d8c3a63a6a61e88 148 Gene3D G3DSA:3.10.450.50 1 133 8.3E-17 T 28-03-2018 SMD44_RS13935 47ed5503484b6394507821de31931aa8 152 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 12 109 2.0E-29 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SMD44_RS13935 47ed5503484b6394507821de31931aa8 152 SUPERFAMILY SSF81301 8 119 2.45E-35 T 28-03-2018 SMD44_RS13935 47ed5503484b6394507821de31931aa8 152 Pfam PF02410 Ribosomal silencing factor during starvation 15 109 1.5E-21 T 28-03-2018 SMD44_RS13935 47ed5503484b6394507821de31931aa8 152 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 22.972 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SMD44_RS13935 47ed5503484b6394507821de31931aa8 152 Gene3D G3DSA:3.30.460.10 5 125 6.7E-29 T 28-03-2018 SMD44_RS04775 0128c5193e0e548f7413977415e3267b 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 295 2.8E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS04775 0128c5193e0e548f7413977415e3267b 304 SUPERFAMILY SSF161098 67 289 1.22E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS04775 0128c5193e0e548f7413977415e3267b 304 Gene3D G3DSA:1.10.3720.10 24 303 1.1E-47 T 28-03-2018 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 89 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 SUPERFAMILY SSF103473 254 463 9.16E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 SUPERFAMILY SSF103473 13 203 9.16E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 426 1.6E-82 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 Pfam PF07690 Major Facilitator Superfamily 24 415 1.0E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 PRINTS PR01035 Tetracycline resistance protein signature 145 167 1.8E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 PRINTS PR01035 Tetracycline resistance protein signature 277 298 1.8E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 PRINTS PR01035 Tetracycline resistance protein signature 32 48 1.8E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 PRINTS PR01035 Tetracycline resistance protein signature 62 81 1.8E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 Gene3D G3DSA:1.20.1250.20 258 475 1.4E-24 T 28-03-2018 SMD44_RS26295 322ba15e6c508ee97f4450631f634e6e 484 Gene3D G3DSA:1.20.1250.20 12 201 3.7E-33 T 28-03-2018 SMD44_RS21000 51bd2f909478bd0ae86d8660f6d182b6 343 Pfam PF01168 Alanine racemase, N-terminal domain 10 169 5.8E-13 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD44_RS21000 51bd2f909478bd0ae86d8660f6d182b6 343 SUPERFAMILY SSF51419 9 176 4.23E-14 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS21000 51bd2f909478bd0ae86d8660f6d182b6 343 Gene3D G3DSA:2.40.37.10 211 342 2.3E-15 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD44_RS21000 51bd2f909478bd0ae86d8660f6d182b6 343 Gene3D G3DSA:3.20.20.10 9 210 4.1E-10 T 28-03-2018 IPR029066 PLP-binding barrel SMD44_RS33100 8abf44c3ceb0907bf1f22df0cf7e9a78 140 Pfam PF06841 T4-like virus tail tube protein gp19 9 139 4.7E-31 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMD44_RS33100 8abf44c3ceb0907bf1f22df0cf7e9a78 140 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 5 139 1.6E-25 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 SMD44_RS21360 dc30c23024cd3f84e9a2303adb9c7a2b 88 Pfam PF03777 Small secreted domain (DUF320) 23 78 1.6E-30 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS12885 e5fab6f08a2f4388e65b863318bba855 304 SUPERFAMILY SSF103481 44 115 5.1E-5 T 28-03-2018 SMD44_RS31230 ef2846566f1725920c6712bcf1161fe6 212 Gene3D G3DSA:1.10.10.10 27 96 3.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31230 ef2846566f1725920c6712bcf1161fe6 212 SUPERFAMILY SSF46785 19 172 3.28E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31230 ef2846566f1725920c6712bcf1161fe6 212 Pfam PF12840 Helix-turn-helix domain 22 77 1.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31230 ef2846566f1725920c6712bcf1161fe6 212 Gene3D G3DSA:1.10.10.10 122 177 0.2 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31230 ef2846566f1725920c6712bcf1161fe6 212 SMART SM00418 22 102 8.7E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS24655 1fc26c94c163086f6cd1b3787a3da7dc 184 Pfam PF04978 Protein of unknown function (DUF664) 34 180 6.7E-44 T 28-03-2018 IPR007061 Protein of unknown function DUF664 SMD44_RS24655 1fc26c94c163086f6cd1b3787a3da7dc 184 SUPERFAMILY SSF109854 21 179 2.14E-42 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS24655 1fc26c94c163086f6cd1b3787a3da7dc 184 Gene3D G3DSA:1.20.120.450 17 184 5.9E-37 T 28-03-2018 SMD44_RS00825 a39fe14a3a5978d1c8c8482cd46db700 180 Gene3D G3DSA:3.40.630.30 1 178 2.8E-31 T 28-03-2018 SMD44_RS00825 a39fe14a3a5978d1c8c8482cd46db700 180 SUPERFAMILY SSF55729 2 170 1.22E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS00825 a39fe14a3a5978d1c8c8482cd46db700 180 Pfam PF13302 Acetyltransferase (GNAT) domain 9 145 4.7E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS40135 8291d652972548e2d8a489bc2005b9df 244 Pfam PF03704 Bacterial transcriptional activator domain 103 236 3.8E-14 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS40135 8291d652972548e2d8a489bc2005b9df 244 SUPERFAMILY SSF48452 102 239 2.28E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS40135 8291d652972548e2d8a489bc2005b9df 244 SMART SM01043 100 243 2.9E-18 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain SMD44_RS40135 8291d652972548e2d8a489bc2005b9df 244 Gene3D G3DSA:1.25.40.10 99 243 8.2E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS20420 ff6dbaf7b8e04a193f9fc5ecb6ab1cad 376 Gene3D G3DSA:1.20.1250.20 1 178 6.3E-19 T 28-03-2018 SMD44_RS20420 ff6dbaf7b8e04a193f9fc5ecb6ab1cad 376 Gene3D G3DSA:1.20.1250.20 192 376 1.8E-13 T 28-03-2018 SMD44_RS20420 ff6dbaf7b8e04a193f9fc5ecb6ab1cad 376 SUPERFAMILY SSF103473 2 373 3.92E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS20420 ff6dbaf7b8e04a193f9fc5ecb6ab1cad 376 Pfam PF07690 Major Facilitator Superfamily 1 219 5.1E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS18875 b7574cca283fa4116164b25889415a50 220 SUPERFAMILY SSF46785 103 192 3.01E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18875 b7574cca283fa4116164b25889415a50 220 Gene3D G3DSA:1.10.10.10 92 189 6.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18875 b7574cca283fa4116164b25889415a50 220 Pfam PF03551 Transcriptional regulator PadR-like family 107 179 7.9E-20 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS37025 302d58e6cd7f66fc90b168e54b13b5a8 226 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 192 211 1.4E-6 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 SMD44_RS23470 cac14615dcc936e62472865091fc5af1 235 Pfam PF00857 Isochorismatase family 30 208 3.3E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS23470 cac14615dcc936e62472865091fc5af1 235 Gene3D G3DSA:3.40.50.850 11 213 1.0E-45 T 28-03-2018 SMD44_RS23470 cac14615dcc936e62472865091fc5af1 235 SUPERFAMILY SSF52499 16 213 3.66E-49 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS21700 8c77f1dd2ab94c2c3ecc44bd63593796 433 Pfam PF05090 Vitamin K-dependent gamma-carboxylase 263 399 7.3E-7 T 28-03-2018 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90|Reactome: R-HSA-159740 SMD44_RS21700 8c77f1dd2ab94c2c3ecc44bd63593796 433 SMART SM00752 16 383 3.8E-93 T 28-03-2018 IPR011020 HTTM Reactome: R-HSA-159740 SMD44_RS21700 8c77f1dd2ab94c2c3ecc44bd63593796 433 ProDom PD031536 MEMBRANE TRANSMEMBRANE YVAX YITN 290 379 7.0E-4 T 28-03-2018 SMD44_RS15305 d44229f3702ca19a5e6f0dd7b531e23d 217 Pfam PF13671 AAA domain 28 178 4.7E-8 T 28-03-2018 SMD44_RS15305 d44229f3702ca19a5e6f0dd7b531e23d 217 SUPERFAMILY SSF52540 21 207 2.85E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS15305 d44229f3702ca19a5e6f0dd7b531e23d 217 Gene3D G3DSA:3.40.50.300 20 210 2.1E-33 T 28-03-2018 SMD44_RS35120 23f0b4ccb7f0bcb7ccd36cfe63486ade 195 SUPERFAMILY SSF46689 3 82 1.55E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS35120 23f0b4ccb7f0bcb7ccd36cfe63486ade 195 SUPERFAMILY SSF48498 79 192 9.93E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS35120 23f0b4ccb7f0bcb7ccd36cfe63486ade 195 Gene3D G3DSA:1.10.357.10 59 195 1.0E-23 T 28-03-2018 SMD44_RS35120 23f0b4ccb7f0bcb7ccd36cfe63486ade 195 Gene3D G3DSA:1.10.10.60 5 58 1.2E-18 T 28-03-2018 SMD44_RS35120 23f0b4ccb7f0bcb7ccd36cfe63486ade 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 4.7E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35120 23f0b4ccb7f0bcb7ccd36cfe63486ade 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 7.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS35120 23f0b4ccb7f0bcb7ccd36cfe63486ade 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 7.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS02580 23167ca21b09620aa79ee58a1a6c5898 636 Gene3D G3DSA:1.10.10.10 584 629 0.0025 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02580 23167ca21b09620aa79ee58a1a6c5898 636 Gene3D G3DSA:1.10.10.10 553 583 0.0036 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02580 23167ca21b09620aa79ee58a1a6c5898 636 Pfam PF13556 PucR C-terminal helix-turn-helix domain 452 506 1.3E-9 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS02580 23167ca21b09620aa79ee58a1a6c5898 636 Gene3D G3DSA:1.10.10.10 258 552 4.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32885 4e5500889f59cb7da5a3e6ad13d1f616 149 SUPERFAMILY SSF54593 22 146 7.65E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS32885 4e5500889f59cb7da5a3e6ad13d1f616 149 Gene3D G3DSA:3.10.180.10 19 149 6.3E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS32885 4e5500889f59cb7da5a3e6ad13d1f616 149 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 23 139 1.4E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS01905 385364481c7318592f3c10de390ed8ce 431 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 272 385 1.5E-11 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMD44_RS01905 385364481c7318592f3c10de390ed8ce 431 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 264 6.4E-17 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS01905 385364481c7318592f3c10de390ed8ce 431 SUPERFAMILY SSF53901 8 269 1.73E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01905 385364481c7318592f3c10de390ed8ce 431 Gene3D G3DSA:3.40.47.10 277 427 2.3E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01905 385364481c7318592f3c10de390ed8ce 431 Gene3D G3DSA:3.40.47.10 1 276 3.3E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS01905 385364481c7318592f3c10de390ed8ce 431 SMART SM00825 Beta-ketoacyl synthase 12 408 1.5E-4 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD44_RS01905 385364481c7318592f3c10de390ed8ce 431 SUPERFAMILY SSF53901 234 427 1.31E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS05670 7529994e21c3f85b083ac5600cac75b6 63 Pfam PF05122 Mobile element transfer protein 13 61 6.1E-20 T 28-03-2018 IPR007806 Mobile element transfer SMD44_RS20340 46845138eea0910750367f6afcc11ef9 193 SUPERFAMILY SSF48498 79 193 1.21E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS20340 46845138eea0910750367f6afcc11ef9 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS20340 46845138eea0910750367f6afcc11ef9 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS20340 46845138eea0910750367f6afcc11ef9 193 SUPERFAMILY SSF46689 1 74 6.98E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS20340 46845138eea0910750367f6afcc11ef9 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 1.2E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS20340 46845138eea0910750367f6afcc11ef9 193 Gene3D G3DSA:1.10.10.60 1 58 4.1E-15 T 28-03-2018 SMD44_RS20340 46845138eea0910750367f6afcc11ef9 193 Gene3D G3DSA:1.10.357.10 59 193 1.3E-24 T 28-03-2018 SMD44_RS38770 90c3bcc93e2b4fd7399a860d519b733b 441 SUPERFAMILY SSF53383 7 412 4.23E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS38770 90c3bcc93e2b4fd7399a860d519b733b 441 Gene3D G3DSA:3.90.1150.10 242 414 2.1E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS38770 90c3bcc93e2b4fd7399a860d519b733b 441 Pfam PF00202 Aminotransferase class-III 43 386 7.4E-39 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS38770 90c3bcc93e2b4fd7399a860d519b733b 441 Gene3D G3DSA:3.90.1150.10 2 200 1.9E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS36900 0fb659320a926f18fc26c9347d59b59a 480 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 41 201 5.2E-15 T 28-03-2018 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 Gene3D G3DSA:3.40.47.10 278 402 2.8E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 Gene3D G3DSA:3.40.47.10 198 277 3.0E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 Gene3D G3DSA:3.40.47.10 1 197 2.5E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 PIRSF PIRSF000429 1 406 1.5E-129 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 3.9E-139 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 SUPERFAMILY SSF53901 3 282 2.76E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 Pfam PF02803 Thiolase, C-terminal domain 282 404 2.6E-47 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 3.1E-60 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD44_RS16715 c7c93dec8ddc7f4b1309faec9c979bba 406 SUPERFAMILY SSF53901 283 404 1.59E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS29355 c74e768957cf96d326e768444eb61192 108 Pfam PF00893 Small Multidrug Resistance protein 1 93 8.5E-24 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMD44_RS29355 c74e768957cf96d326e768444eb61192 108 SUPERFAMILY SSF103481 6 105 1.44E-16 T 28-03-2018 SMD44_RS25120 e7c140d8b4c89d9e48869815ae08be22 378 Pfam PF14027 Protein of unknown function (DUF4243) 31 334 3.8E-17 T 28-03-2018 IPR025337 Domain of unknown function DUF4243 SMD44_RS05070 822c473142dcf8fa9f9c76a129e48fca 103 Gene3D G3DSA:3.30.70.1060 2 103 2.1E-25 T 28-03-2018 SMD44_RS05070 822c473142dcf8fa9f9c76a129e48fca 103 Pfam PF03795 YCII-related domain 6 101 1.6E-14 T 28-03-2018 IPR005545 YCII-related SMD44_RS05070 822c473142dcf8fa9f9c76a129e48fca 103 SUPERFAMILY SSF54909 7 101 8.58E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS33685 f2d120e32b96dd080972cf367bade147 98 Pfam PF01527 Transposase 6 76 1.2E-16 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 SMD44_RS33685 f2d120e32b96dd080972cf367bade147 98 Gene3D G3DSA:1.10.10.10 1 74 2.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS33685 f2d120e32b96dd080972cf367bade147 98 SUPERFAMILY SSF46689 6 95 3.76E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS08575 a8d49a3a4668553843c2c31bf7eb81d2 154 SUPERFAMILY SSF54637 11 151 2.57E-41 T 28-03-2018 IPR029069 HotDog domain SMD44_RS08575 a8d49a3a4668553843c2c31bf7eb81d2 154 Gene3D G3DSA:3.10.129.10 4 154 3.3E-40 T 28-03-2018 SMD44_RS08575 a8d49a3a4668553843c2c31bf7eb81d2 154 Pfam PF01575 MaoC like domain 15 134 6.7E-28 T 28-03-2018 IPR002539 MaoC-like domain SMD44_RS26070 fb2b7b2ff8e971aed3fe3e00f71819a1 386 SUPERFAMILY SSF55874 257 372 4.66E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26070 fb2b7b2ff8e971aed3fe3e00f71819a1 386 Pfam PF07730 Histidine kinase 171 236 9.2E-20 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS26070 fb2b7b2ff8e971aed3fe3e00f71819a1 386 Gene3D G3DSA:3.30.565.10 250 379 7.5E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26070 fb2b7b2ff8e971aed3fe3e00f71819a1 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 373 9.9E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS26070 fb2b7b2ff8e971aed3fe3e00f71819a1 386 SMART SM00387 281 375 5.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04185 591a2d6d37a59fd5ea679d3eabad4534 392 SUPERFAMILY SSF55874 272 382 5.82E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04185 591a2d6d37a59fd5ea679d3eabad4534 392 Pfam PF07730 Histidine kinase 185 249 4.9E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS04185 591a2d6d37a59fd5ea679d3eabad4534 392 Gene3D G3DSA:3.30.565.10 261 389 3.4E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS13265 fe1e5e4678486227f5b45f6350b6e19e 59 SUPERFAMILY SSF52091 2 54 2.35E-5 T 28-03-2018 IPR002645 STAS domain SMD44_RS13265 fe1e5e4678486227f5b45f6350b6e19e 59 Gene3D G3DSA:3.30.750.24 1 58 8.5E-4 T 28-03-2018 IPR002645 STAS domain SMD44_RS42740 e03bd23667343dcf948541a5b4c3bd1e 344 Pfam PF13353 4Fe-4S single cluster domain 12 131 8.7E-5 T 28-03-2018 SMD44_RS42740 e03bd23667343dcf948541a5b4c3bd1e 344 SMART SM00729 6 231 6.4E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD44_RS42740 e03bd23667343dcf948541a5b4c3bd1e 344 SUPERFAMILY SSF102114 7 320 4.84E-39 T 28-03-2018 SMD44_RS42740 e03bd23667343dcf948541a5b4c3bd1e 344 Pfam PF04055 Radical SAM superfamily 15 188 4.8E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS42740 e03bd23667343dcf948541a5b4c3bd1e 344 Gene3D G3DSA:3.20.20.70 5 313 1.9E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS07910 3edd6ce04da5fe86a87d9acd422ab939 285 SUPERFAMILY SSF75217 100 277 7.85E-41 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases SMD44_RS07910 3edd6ce04da5fe86a87d9acd422ab939 285 SMART SM00967 34 112 1.9E-11 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SMD44_RS07910 3edd6ce04da5fe86a87d9acd422ab939 285 Gene3D G3DSA:3.40.1280.10 114 275 1.9E-44 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD44_RS07910 3edd6ce04da5fe86a87d9acd422ab939 285 Gene3D G3DSA:3.30.1330.30 1 108 2.9E-25 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SMD44_RS07910 3edd6ce04da5fe86a87d9acd422ab939 285 SUPERFAMILY SSF55315 7 109 1.88E-18 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like SMD44_RS07910 3edd6ce04da5fe86a87d9acd422ab939 285 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 34 109 1.2E-8 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SMD44_RS07910 3edd6ce04da5fe86a87d9acd422ab939 285 Pfam PF00588 SpoU rRNA Methylase family 123 267 1.9E-36 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMD44_RS28550 82410b8bf6355116416db72cc09cedaf 186 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 139 182 1.1E-6 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS28550 82410b8bf6355116416db72cc09cedaf 186 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 24 57 0.044 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS28550 82410b8bf6355116416db72cc09cedaf 186 Gene3D G3DSA:1.10.1780.10 1 73 2.0E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS28550 82410b8bf6355116416db72cc09cedaf 186 SUPERFAMILY SSF81923 3 67 5.36E-7 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS28550 82410b8bf6355116416db72cc09cedaf 186 Gene3D G3DSA:1.10.1780.10 74 186 3.9E-21 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS28550 82410b8bf6355116416db72cc09cedaf 186 SUPERFAMILY SSF81923 118 183 8.37E-9 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMD44_RS39780 c489c06984f17cd99d53045d8b86871c 259 Pfam PF04909 Amidohydrolase 119 219 1.1E-21 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS39780 c489c06984f17cd99d53045d8b86871c 259 Gene3D G3DSA:3.20.20.140 19 233 3.7E-28 T 28-03-2018 SMD44_RS39780 c489c06984f17cd99d53045d8b86871c 259 SUPERFAMILY SSF51556 56 223 1.73E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS16605 a1f7baf7bf64f3e750a685ba8a75483a 122 Gene3D G3DSA:3.30.750.24 10 122 3.6E-24 T 28-03-2018 IPR002645 STAS domain SMD44_RS16605 a1f7baf7bf64f3e750a685ba8a75483a 122 Pfam PF13466 STAS domain 30 106 3.4E-16 T 28-03-2018 IPR002645 STAS domain SMD44_RS16605 a1f7baf7bf64f3e750a685ba8a75483a 122 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 117 3.2E-23 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD44_RS16605 a1f7baf7bf64f3e750a685ba8a75483a 122 SUPERFAMILY SSF52091 17 121 5.3E-26 T 28-03-2018 IPR002645 STAS domain SMD44_RS15880 3f86116288b9193674f7789bc2fa8256 181 Gene3D G3DSA:3.40.50.300 2 181 1.0E-16 T 28-03-2018 SMD44_RS15880 3f86116288b9193674f7789bc2fa8256 181 Pfam PF13671 AAA domain 10 147 1.7E-9 T 28-03-2018 SMD44_RS15880 3f86116288b9193674f7789bc2fa8256 181 SUPERFAMILY SSF52540 10 177 2.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16970 2cf482e5be04d416c9a93014f2e9abd4 343 Pfam PF00487 Fatty acid desaturase 63 289 6.7E-21 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SMD44_RS16970 2cf482e5be04d416c9a93014f2e9abd4 343 PRINTS PR00075 Fatty acid desaturase family 1 signature 265 279 2.1E-16 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD44_RS16970 2cf482e5be04d416c9a93014f2e9abd4 343 PRINTS PR00075 Fatty acid desaturase family 1 signature 62 84 2.1E-16 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD44_RS16970 2cf482e5be04d416c9a93014f2e9abd4 343 PRINTS PR00075 Fatty acid desaturase family 1 signature 85 105 2.1E-16 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD44_RS16970 2cf482e5be04d416c9a93014f2e9abd4 343 PRINTS PR00075 Fatty acid desaturase family 1 signature 222 243 2.1E-16 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD44_RS35500 4006dbe73fbdc41ad6bedd80ead063d7 250 SMART SM00382 56 239 2.9E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS35500 4006dbe73fbdc41ad6bedd80ead063d7 250 Gene3D G3DSA:3.40.50.300 2 250 4.1E-45 T 28-03-2018 SMD44_RS35500 4006dbe73fbdc41ad6bedd80ead063d7 250 SUPERFAMILY SSF52540 42 244 1.36E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS35500 4006dbe73fbdc41ad6bedd80ead063d7 250 Pfam PF00005 ABC transporter 48 181 1.0E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS35500 4006dbe73fbdc41ad6bedd80ead063d7 250 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS11420 27a8dfb6670ac29aee25066ff3b4b2c5 324 Pfam PF00294 pfkB family carbohydrate kinase 32 295 2.5E-38 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS11420 27a8dfb6670ac29aee25066ff3b4b2c5 324 SUPERFAMILY SSF53613 2 295 7.79E-51 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS11420 27a8dfb6670ac29aee25066ff3b4b2c5 324 Gene3D G3DSA:3.40.1190.20 1 323 6.2E-42 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS43305 4474a8460b6d99d3aac9282fe7776825 256 Gene3D G3DSA:1.10.10.10 3 68 1.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24765 230767555a3da5a0e38171465e1eff6c 410 SUPERFAMILY SSF53335 114 249 3.54E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS24765 230767555a3da5a0e38171465e1eff6c 410 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 119 270 1.6E-24 T 28-03-2018 SMD44_RS24765 230767555a3da5a0e38171465e1eff6c 410 Gene3D G3DSA:3.40.50.150 36 291 1.7E-25 T 28-03-2018 SMD44_RS38000 10f051f4d097873977b588e2a798187b 256 Gene3D G3DSA:3.40.50.410 12 237 5.6E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS38000 10f051f4d097873977b588e2a798187b 256 SUPERFAMILY SSF53300 17 200 8.75E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS38000 10f051f4d097873977b588e2a798187b 256 SMART SM00327 15 219 6.9E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS43640 96125873978e289e07249d3bd41cef99 121 Pfam PF14216 Domain of unknown function (DUF4326) 14 96 1.1E-12 T 28-03-2018 IPR025475 Protein of unknown function DUF4326) SMD44_RS23170 74fe8bbb8fd30ae758d6dc91d30c711d 309 SUPERFAMILY SSF55811 64 98 2.58E-13 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS23170 74fe8bbb8fd30ae758d6dc91d30c711d 309 SUPERFAMILY SSF55811 182 248 2.58E-13 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS23170 74fe8bbb8fd30ae758d6dc91d30c711d 309 SUPERFAMILY SSF55811 126 137 2.58E-13 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS23170 74fe8bbb8fd30ae758d6dc91d30c711d 309 Gene3D G3DSA:3.90.79.10 23 266 1.9E-30 T 28-03-2018 SMD44_RS14115 6de1bdf5bf1d428c65659c2e51eb9012 449 Pfam PF13641 Glycosyltransferase like family 2 48 299 1.5E-22 T 28-03-2018 SMD44_RS14115 6de1bdf5bf1d428c65659c2e51eb9012 449 SUPERFAMILY SSF53448 49 313 3.28E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS14115 6de1bdf5bf1d428c65659c2e51eb9012 449 Gene3D G3DSA:3.90.550.10 22 339 6.1E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS02595 94c13c7bd4ca7060cebb5847a94a242a 508 Pfam PF13556 PucR C-terminal helix-turn-helix domain 429 482 3.6E-11 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS02595 94c13c7bd4ca7060cebb5847a94a242a 508 Pfam PF13556 PucR C-terminal helix-turn-helix domain 308 363 2.6E-10 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS02595 94c13c7bd4ca7060cebb5847a94a242a 508 Gene3D G3DSA:1.10.10.10 294 380 1.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02595 94c13c7bd4ca7060cebb5847a94a242a 508 Gene3D G3DSA:1.10.10.60 422 462 5.9E-5 T 28-03-2018 SMD44_RS38275 2938c5edf60bfb6c9073f11a009e4007 225 Gene3D G3DSA:1.10.3720.10 2 216 1.3E-27 T 28-03-2018 SMD44_RS38275 2938c5edf60bfb6c9073f11a009e4007 225 SUPERFAMILY SSF161098 20 205 2.35E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS38275 2938c5edf60bfb6c9073f11a009e4007 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 208 3.5E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS42985 6836935478e38b09be51c1095edccabb 232 Gene3D G3DSA:3.90.1530.10 39 162 8.6E-10 T 28-03-2018 SMD44_RS42985 6836935478e38b09be51c1095edccabb 232 SMART SM00470 46 159 0.003 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS42985 6836935478e38b09be51c1095edccabb 232 Pfam PF02195 ParB-like nuclease domain 47 147 2.4E-7 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS42985 6836935478e38b09be51c1095edccabb 232 SUPERFAMILY SSF110849 45 179 2.96E-13 T 28-03-2018 IPR003115 ParB/Sulfiredoxin SMD44_RS12895 3e091a09278f00d86a14463719d7687b 274 Pfam PF05050 Methyltransferase FkbM domain 47 198 8.2E-14 T 28-03-2018 IPR006342 Methyltransferase FkbM SMD44_RS12895 3e091a09278f00d86a14463719d7687b 274 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 51 183 5.0E-20 T 28-03-2018 IPR006342 Methyltransferase FkbM SMD44_RS12895 3e091a09278f00d86a14463719d7687b 274 Gene3D G3DSA:3.40.50.150 38 209 4.9E-29 T 28-03-2018 SMD44_RS12895 3e091a09278f00d86a14463719d7687b 274 SUPERFAMILY SSF53335 28 213 4.17E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS19695 cc71847d23d6892b64f99b06470c7013 211 SMART SM00226 82 207 1.9E-34 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS19695 cc71847d23d6892b64f99b06470c7013 211 SUPERFAMILY SSF52788 81 206 1.57E-33 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS19695 cc71847d23d6892b64f99b06470c7013 211 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 84 205 1.4E-18 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD44_RS19695 cc71847d23d6892b64f99b06470c7013 211 Gene3D G3DSA:3.40.50.2300 80 211 8.8E-33 T 28-03-2018 SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 169 197 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 SUPERFAMILY SSF51735 17 271 1.49E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 Gene3D G3DSA:3.40.50.720 9 273 4.8E-60 T 28-03-2018 SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 3.8E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 220 3.8E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 3.8E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 201 3.8E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 172 3.8E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 Pfam PF00106 short chain dehydrogenase 19 221 2.4E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 103 114 9.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS35160 4a97ba71aba76b844d53ff9d7604a299 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 201 9.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS04515 3b71f748afbd210383db2ccdf6802e2f 81 Gene3D G3DSA:1.10.10.10 2 79 2.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31490 f73b30131b3a36a7452b39ca288fbe06 223 Gene3D G3DSA:3.40.50.970 78 221 0.0015 T 28-03-2018 SMD44_RS29020 b805d26c1a4c58c1230c3571b3c6cd38 1294 Gene3D G3DSA:1.20.5.620 285 338 0.0055 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD44_RS29020 b805d26c1a4c58c1230c3571b3c6cd38 1294 Gene3D G3DSA:1.20.5.620 972 1016 0.068 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD44_RS29020 b805d26c1a4c58c1230c3571b3c6cd38 1294 Gene3D G3DSA:1.20.5.620 1174 1246 4.5E-5 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD44_RS29020 b805d26c1a4c58c1230c3571b3c6cd38 1294 Gene3D G3DSA:1.20.5.620 597 656 0.01 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD44_RS29020 b805d26c1a4c58c1230c3571b3c6cd38 1294 Gene3D G3DSA:1.20.120.20 731 924 1.7E-6 T 28-03-2018 SMD44_RS29020 b805d26c1a4c58c1230c3571b3c6cd38 1294 Gene3D G3DSA:1.20.5.1230 361 596 0.029 T 28-03-2018 SMD44_RS29020 b805d26c1a4c58c1230c3571b3c6cd38 1294 Gene3D G3DSA:1.20.120.20 1017 1173 0.0011 T 28-03-2018 SMD44_RS29020 b805d26c1a4c58c1230c3571b3c6cd38 1294 Gene3D G3DSA:1.20.120.20 123 284 2.5E-4 T 28-03-2018 SMD44_RS33695 6670bf7bf409581f95dc4006b6ad2816 352 Pfam PF00487 Fatty acid desaturase 64 330 4.0E-31 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SMD44_RS08385 ad6f295e82b8505ea95d0915c4c3f0c2 50 Gene3D G3DSA:1.10.10.10 1 50 1.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08385 ad6f295e82b8505ea95d0915c4c3f0c2 50 Pfam PF12728 Helix-turn-helix domain 1 49 3.0E-11 T 28-03-2018 SMD44_RS37740 3b44090ec535e2168237b4dac2b6f1fb 210 Gene3D G3DSA:1.10.10.60 4 58 1.9E-15 T 28-03-2018 SMD44_RS37740 3b44090ec535e2168237b4dac2b6f1fb 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 76 187 2.9E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS37740 3b44090ec535e2168237b4dac2b6f1fb 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS37740 3b44090ec535e2168237b4dac2b6f1fb 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS37740 3b44090ec535e2168237b4dac2b6f1fb 210 SUPERFAMILY SSF46689 11 69 4.32E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS37740 3b44090ec535e2168237b4dac2b6f1fb 210 Gene3D G3DSA:1.10.357.10 62 200 3.7E-21 T 28-03-2018 SMD44_RS37740 3b44090ec535e2168237b4dac2b6f1fb 210 SUPERFAMILY SSF48498 78 193 2.37E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS37740 3b44090ec535e2168237b4dac2b6f1fb 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 7.9E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS30455 f14581a36a231635066d692930c5d5a9 190 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 129 1.4E-6 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD44_RS30455 f14581a36a231635066d692930c5d5a9 190 Gene3D G3DSA:1.20.120.450 4 128 5.3E-5 T 28-03-2018 SMD44_RS30455 f14581a36a231635066d692930c5d5a9 190 SUPERFAMILY SSF109854 5 135 7.32E-7 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS01875 36a0c745f2f2c60a9ab3522e31e2e9fe 449 Gene3D G3DSA:3.90.1150.10 318 446 7.3E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS01875 36a0c745f2f2c60a9ab3522e31e2e9fe 449 PIRSF PIRSF000521 24 164 3.4E-4 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS01875 36a0c745f2f2c60a9ab3522e31e2e9fe 449 PIRSF PIRSF000521 185 434 1.6E-19 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS01875 36a0c745f2f2c60a9ab3522e31e2e9fe 449 Gene3D G3DSA:3.40.640.10 185 317 3.3E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS01875 36a0c745f2f2c60a9ab3522e31e2e9fe 449 SUPERFAMILY SSF53383 29 433 5.31E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS01875 36a0c745f2f2c60a9ab3522e31e2e9fe 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 277 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS01875 36a0c745f2f2c60a9ab3522e31e2e9fe 449 Pfam PF00202 Aminotransferase class-III 30 429 4.5E-73 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD44_RS01875 36a0c745f2f2c60a9ab3522e31e2e9fe 449 Gene3D G3DSA:3.90.1150.10 10 178 8.5E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS03850 bd7758811b5653444799baf2b7f27fb9 378 Gene3D G3DSA:3.50.50.60 7 360 1.2E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03850 bd7758811b5653444799baf2b7f27fb9 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 9.0E-17 T 28-03-2018 SMD44_RS03850 bd7758811b5653444799baf2b7f27fb9 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 9.0E-17 T 28-03-2018 SMD44_RS03850 bd7758811b5653444799baf2b7f27fb9 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 9.0E-17 T 28-03-2018 SMD44_RS03850 bd7758811b5653444799baf2b7f27fb9 378 Pfam PF01494 FAD binding domain 292 353 1.9E-7 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS03850 bd7758811b5653444799baf2b7f27fb9 378 Pfam PF01494 FAD binding domain 9 80 5.8E-6 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS03850 bd7758811b5653444799baf2b7f27fb9 378 SUPERFAMILY SSF51905 282 360 4.8E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03850 bd7758811b5653444799baf2b7f27fb9 378 SUPERFAMILY SSF51905 10 175 4.8E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS35035 23df8ed1c5f7217db5d0c3c868144f22 167 Gene3D G3DSA:3.10.129.10 3 158 9.3E-24 T 28-03-2018 SMD44_RS35035 23df8ed1c5f7217db5d0c3c868144f22 167 SUPERFAMILY SSF54637 11 160 2.07E-36 T 28-03-2018 IPR029069 HotDog domain SMD44_RS35035 23df8ed1c5f7217db5d0c3c868144f22 167 Pfam PF13279 Thioesterase-like superfamily 16 144 3.4E-17 T 28-03-2018 SMD44_RS23075 e0e5e6cc4d3bbb687b163e5499c3df69 243 Gene3D G3DSA:3.30.450.40 25 171 5.2E-15 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS23075 e0e5e6cc4d3bbb687b163e5499c3df69 243 Gene3D G3DSA:1.10.10.10 181 227 3.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS23075 e0e5e6cc4d3bbb687b163e5499c3df69 243 SUPERFAMILY SSF55781 27 158 1.72E-11 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS40570 35824a34b2f89128c92ae8bdce6a1e08 110 SUPERFAMILY SSF55874 16 103 3.01E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS40570 35824a34b2f89128c92ae8bdce6a1e08 110 Gene3D G3DSA:3.30.565.10 1 110 2.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS40570 35824a34b2f89128c92ae8bdce6a1e08 110 Pfam PF13581 Histidine kinase-like ATPase domain 3 101 1.7E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28025 864a29800dbe423220085c115ef07b51 317 Gene3D G3DSA:3.40.50.720 1 177 2.2E-17 T 28-03-2018 SMD44_RS28025 864a29800dbe423220085c115ef07b51 317 SUPERFAMILY SSF51735 1 310 2.14E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS28025 864a29800dbe423220085c115ef07b51 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 4.4E-31 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS28025 864a29800dbe423220085c115ef07b51 317 Gene3D G3DSA:3.90.25.10 178 316 8.0E-37 T 28-03-2018 SMD44_RS24815 f58251dc1804bd8a80301c7958a9e90e 310 Gene3D G3DSA:3.40.80.10 18 203 1.7E-26 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS24815 f58251dc1804bd8a80301c7958a9e90e 310 SUPERFAMILY SSF55846 18 180 3.74E-23 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS24815 f58251dc1804bd8a80301c7958a9e90e 310 SUPERFAMILY SSF47090 242 301 3.84E-7 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS24815 f58251dc1804bd8a80301c7958a9e90e 310 SMART SM00644 27 180 8.8E-23 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS24815 f58251dc1804bd8a80301c7958a9e90e 310 Gene3D G3DSA:1.10.101.10 236 308 7.0E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like SMD44_RS24815 f58251dc1804bd8a80301c7958a9e90e 310 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 40 179 1.4E-18 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMD44_RS36395 1bfeae66446da6a612de0baac3796ef0 335 Gene3D G3DSA:1.25.40.120 46 327 0.0018 T 28-03-2018 SMD44_RS20660 1ccbc99c6aa1e14e3d9cf9e67020778c 393 Pfam PF00994 Probable molybdopterin binding domain 13 173 4.1E-26 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS20660 1ccbc99c6aa1e14e3d9cf9e67020778c 393 Gene3D G3DSA:3.40.980.10 9 178 4.4E-34 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS20660 1ccbc99c6aa1e14e3d9cf9e67020778c 393 SUPERFAMILY SSF53218 10 209 1.44E-30 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS20660 1ccbc99c6aa1e14e3d9cf9e67020778c 393 SMART SM00852 13 179 1.1E-22 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS08945 35552ec4c5e9bf977ad3407b7d4b0267 148 Hamap MF_01197 Cell division protein SepF [sepF]. 1 139 19.308 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 SMD44_RS08945 35552ec4c5e9bf977ad3407b7d4b0267 148 Pfam PF04472 Cell division protein SepF 62 131 2.6E-25 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SMD44_RS14030 05d7f3fa7dd765b57646988a3f01e05e 689 SUPERFAMILY SSF52980 390 501 5.9E-21 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS14030 05d7f3fa7dd765b57646988a3f01e05e 689 Pfam PF02342 TerD domain 541 684 6.7E-21 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS14030 05d7f3fa7dd765b57646988a3f01e05e 689 Gene3D G3DSA:3.40.1350.10 379 505 3.6E-24 T 28-03-2018 SMD44_RS14030 05d7f3fa7dd765b57646988a3f01e05e 689 Gene3D G3DSA:2.60.60.30 524 682 3.5E-23 T 28-03-2018 SMD44_RS14030 05d7f3fa7dd765b57646988a3f01e05e 689 Pfam PF04471 Restriction endonuclease 385 498 1.8E-28 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 SMD44_RS33150 81cae9d909bf31d502a1ecef67969c5b 470 Gene3D G3DSA:2.60.40.10 109 214 0.25 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS33150 81cae9d909bf31d502a1ecef67969c5b 470 SMART SM00728 339 386 9.0E-5 T 28-03-2018 IPR006637 Clostridial hydrophobic repeat SMD44_RS33150 81cae9d909bf31d502a1ecef67969c5b 470 Gene3D G3DSA:2.60.40.10 11 107 6.4E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS33150 81cae9d909bf31d502a1ecef67969c5b 470 Pfam PF07538 Clostridial hydrophobic W 340 372 3.6E-6 T 28-03-2018 IPR006637 Clostridial hydrophobic repeat SMD44_RS27030 c40db30fb0fe1c9de1be5a99e79ee052 416 SUPERFAMILY SSF141523 253 361 4.71E-21 T 28-03-2018 SMD44_RS27030 c40db30fb0fe1c9de1be5a99e79ee052 416 Pfam PF13205 Bacterial Ig-like domain 153 245 1.7E-7 T 28-03-2018 IPR032812 SbsA, Ig-like domain SMD44_RS27030 c40db30fb0fe1c9de1be5a99e79ee052 416 Gene3D G3DSA:2.40.440.10 246 388 8.1E-27 T 28-03-2018 SMD44_RS27030 c40db30fb0fe1c9de1be5a99e79ee052 416 Pfam PF03734 L,D-transpeptidase catalytic domain 251 362 1.0E-13 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD44_RS27030 c40db30fb0fe1c9de1be5a99e79ee052 416 Gene3D G3DSA:2.60.40.1220 147 245 0.071 T 28-03-2018 SMD44_RS25315 b469f7e45b36287f76f86331f0576a7b 144 PIRSF PIRSF028777 1 130 8.0E-50 T 28-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 SMD44_RS25315 b469f7e45b36287f76f86331f0576a7b 144 Pfam PF03733 Inner membrane component domain 68 118 4.4E-17 T 28-03-2018 IPR005185 Inner membrane component domain SMD44_RS25315 b469f7e45b36287f76f86331f0576a7b 144 Pfam PF03733 Inner membrane component domain 4 54 2.5E-17 T 28-03-2018 IPR005185 Inner membrane component domain SMD44_RS01235 8d4c9ddb0cafb1a3be01c5cc63177306 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 1.4E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS01235 8d4c9ddb0cafb1a3be01c5cc63177306 222 SUPERFAMILY SSF46894 120 221 3.68E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS01235 8d4c9ddb0cafb1a3be01c5cc63177306 222 Gene3D G3DSA:3.40.50.2300 1 118 1.2E-32 T 28-03-2018 SMD44_RS01235 8d4c9ddb0cafb1a3be01c5cc63177306 222 SMART SM00448 1 112 4.8E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS01235 8d4c9ddb0cafb1a3be01c5cc63177306 222 Pfam PF00072 Response regulator receiver domain 3 112 3.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS01235 8d4c9ddb0cafb1a3be01c5cc63177306 222 Gene3D G3DSA:1.10.10.10 119 222 7.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01235 8d4c9ddb0cafb1a3be01c5cc63177306 222 SUPERFAMILY SSF52172 2 132 1.11E-38 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS01235 8d4c9ddb0cafb1a3be01c5cc63177306 222 SMART SM00862 145 220 3.8E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS12630 670d0d3b78f44ff5f96d271145f53e86 449 Gene3D G3DSA:1.20.120.330 46 194 0.011 T 28-03-2018 SMD44_RS12630 670d0d3b78f44ff5f96d271145f53e86 449 Gene3D G3DSA:1.20.120.330 200 447 1.9E-4 T 28-03-2018 SMD44_RS22510 8849f4a45b2bd2dcb447e658d334dd3c 326 Gene3D G3DSA:3.60.15.10 5 255 2.2E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS22510 8849f4a45b2bd2dcb447e658d334dd3c 326 SMART SM00849 29 229 9.4E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS22510 8849f4a45b2bd2dcb447e658d334dd3c 326 Pfam PF00753 Metallo-beta-lactamase superfamily 27 229 6.3E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS22510 8849f4a45b2bd2dcb447e658d334dd3c 326 SUPERFAMILY SSF56281 11 282 3.93E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS09220 f95b626079b15c89364621a0f00b8b74 425 PIRSF PIRSF033563 11 425 2.9E-117 T 28-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 SMD44_RS09220 f95b626079b15c89364621a0f00b8b74 425 Pfam PF06245 Protein of unknown function (DUF1015) 14 421 2.3E-114 T 28-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 SMD44_RS23400 734abdb828ae73c00f75ad37671fab2c 216 Gene3D G3DSA:3.40.50.150 6 213 5.0E-39 T 28-03-2018 SMD44_RS23400 734abdb828ae73c00f75ad37671fab2c 216 SUPERFAMILY SSF53335 10 192 6.81E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS23400 734abdb828ae73c00f75ad37671fab2c 216 Pfam PF13649 Methyltransferase domain 54 144 6.1E-19 T 28-03-2018 SMD44_RS27800 2e239e315abe9031d3d1fcb8388db554 106 SUPERFAMILY SSF54862 3 87 3.03E-22 T 28-03-2018 SMD44_RS27800 2e239e315abe9031d3d1fcb8388db554 106 Pfam PF00037 4Fe-4S binding domain 34 55 1.2E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD44_RS27800 2e239e315abe9031d3d1fcb8388db554 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD44_RS27800 2e239e315abe9031d3d1fcb8388db554 106 Gene3D G3DSA:3.30.70.20 45 95 8.7E-9 T 28-03-2018 SMD44_RS27800 2e239e315abe9031d3d1fcb8388db554 106 Gene3D G3DSA:3.30.70.20 2 44 2.1E-11 T 28-03-2018 SMD44_RS27800 2e239e315abe9031d3d1fcb8388db554 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 3.9E-18 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SMD44_RS27800 2e239e315abe9031d3d1fcb8388db554 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 3.9E-18 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SMD44_RS27800 2e239e315abe9031d3d1fcb8388db554 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 3.9E-18 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SMD44_RS37665 3a00585d423252468725f587389bd8ac 152 Pfam PF00571 CBS domain 5 56 0.0057 T 28-03-2018 IPR000644 CBS domain SMD44_RS37665 3a00585d423252468725f587389bd8ac 152 SUPERFAMILY SSF54631 1 149 4.93E-10 T 28-03-2018 SMD44_RS37665 3a00585d423252468725f587389bd8ac 152 Gene3D G3DSA:3.10.580.10 1 152 4.3E-11 T 28-03-2018 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 SUPERFAMILY SSF52954 296 407 2.94E-17 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 Pfam PF03129 Anticodon binding domain 308 381 4.2E-7 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 PRINTS PR01047 Threonyl-tRNA synthetase signature 301 313 2.8E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 PRINTS PR01047 Threonyl-tRNA synthetase signature 231 259 2.8E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 PRINTS PR01047 Threonyl-tRNA synthetase signature 94 122 2.8E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 PRINTS PR01047 Threonyl-tRNA synthetase signature 127 150 2.8E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 PRINTS PR01047 Threonyl-tRNA synthetase signature 274 287 2.8E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 4 382 1.0E-130 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 Gene3D G3DSA:3.30.930.10 2 293 5.0E-91 T 28-03-2018 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 89 296 1.0E-26 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 Gene3D G3DSA:3.40.50.800 294 404 1.1E-14 T 28-03-2018 IPR004154 Anticodon-binding SMD44_RS03270 75f46676f007a1a7fc98263ca4cbd996 412 SUPERFAMILY SSF55681 6 293 3.11E-84 T 28-03-2018 SMD44_RS35365 e4b240ca8181a88e72ac6b8af53bb912 487 Pfam PF00324 Amino acid permease 36 441 9.6E-108 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD44_RS35365 e4b240ca8181a88e72ac6b8af53bb912 487 PIRSF PIRSF006060 13 487 3.0E-66 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS35365 e4b240ca8181a88e72ac6b8af53bb912 487 ProSitePatterns PS00218 Amino acid permeases signature. 61 91 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD44_RS09710 4df9d3c841db625dc2d952cb2d98cfcb 299 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 24 299 1.8E-146 T 28-03-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 SMD44_RS09710 4df9d3c841db625dc2d952cb2d98cfcb 299 SUPERFAMILY SSF51197 33 297 1.92E-58 T 28-03-2018 SMD44_RS09710 4df9d3c841db625dc2d952cb2d98cfcb 299 Gene3D G3DSA:2.60.120.620 28 286 3.2E-41 T 28-03-2018 SMD44_RS09710 4df9d3c841db625dc2d952cb2d98cfcb 299 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 47 262 6.9E-37 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMD44_RS26590 41ddb82c96efabfc45f7a75a4a482976 229 SUPERFAMILY SSF158694 51 198 1.7E-27 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMD44_RS26590 41ddb82c96efabfc45f7a75a4a482976 229 Pfam PF09349 OHCU decarboxylase 126 194 5.7E-10 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMD44_RS26590 41ddb82c96efabfc45f7a75a4a482976 229 Pfam PF09349 OHCU decarboxylase 54 114 5.9E-7 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMD44_RS26590 41ddb82c96efabfc45f7a75a4a482976 229 Gene3D G3DSA:1.10.3330.10 33 201 5.9E-37 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMD44_RS22820 13afb94e73194329cc297dc53e28d126 271 SUPERFAMILY SSF47413 20 63 1.01E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS22820 13afb94e73194329cc297dc53e28d126 271 Gene3D G3DSA:1.10.260.40 19 103 5.9E-11 T 28-03-2018 SMD44_RS22820 13afb94e73194329cc297dc53e28d126 271 Pfam PF13560 Helix-turn-helix domain 20 74 2.8E-10 T 28-03-2018 SMD44_RS22820 13afb94e73194329cc297dc53e28d126 271 SMART SM00530 22 75 3.6E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS28675 52a6c1d04dd0a25f879c83215824576a 411 SUPERFAMILY SSF51905 282 357 1.86E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS28675 52a6c1d04dd0a25f879c83215824576a 411 SUPERFAMILY SSF51905 2 157 1.86E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS28675 52a6c1d04dd0a25f879c83215824576a 411 Gene3D G3DSA:3.50.50.60 3 360 7.1E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS28675 52a6c1d04dd0a25f879c83215824576a 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 1.3E-5 T 28-03-2018 SMD44_RS28675 52a6c1d04dd0a25f879c83215824576a 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.3E-5 T 28-03-2018 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 SMART SM00191 30 90 4.7 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 SMART SM00191 102 163 2.5 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 SMART SM00191 425 481 31.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 SMART SM00191 284 340 190.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 SMART SM00191 355 411 9.8E-4 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Gene3D G3DSA:2.60.40.680 119 197 7.4E-9 T 28-03-2018 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Gene3D G3DSA:2.60.40.680 440 497 0.15 T 28-03-2018 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Gene3D G3DSA:2.60.40.680 17 118 9.3E-15 T 28-03-2018 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Gene3D G3DSA:2.60.40.680 375 439 2.0E-10 T 28-03-2018 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Gene3D G3DSA:2.60.40.680 286 374 9.8E-17 T 28-03-2018 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Gene3D G3DSA:2.60.40.680 220 285 0.063 T 28-03-2018 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Pfam PF01839 FG-GAP repeat 360 397 1.6E-7 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Pfam PF01839 FG-GAP repeat 289 314 1.5E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 Pfam PF01839 FG-GAP repeat 44 73 3.7E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS05030 b2df3d9b3e48b45cc127b0b4752b845c 498 SUPERFAMILY SSF69318 43 455 4.06E-53 T 28-03-2018 SMD44_RS31210 1f63cfdf43b9ba24766f97d6426e7afa 311 Pfam PF00106 short chain dehydrogenase 17 156 8.5E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31210 1f63cfdf43b9ba24766f97d6426e7afa 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 6.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31210 1f63cfdf43b9ba24766f97d6426e7afa 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 6.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31210 1f63cfdf43b9ba24766f97d6426e7afa 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 6.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS31210 1f63cfdf43b9ba24766f97d6426e7afa 311 Gene3D G3DSA:3.40.50.720 1 307 1.2E-49 T 28-03-2018 SMD44_RS31210 1f63cfdf43b9ba24766f97d6426e7afa 311 SUPERFAMILY SSF51735 15 224 1.51E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS06070 22b9154d0e2dcf96991b9b89a8c8c4bc 570 Pfam PF05960 Bacterial protein of unknown function (DUF885) 33 566 2.5E-145 T 28-03-2018 IPR010281 Protein of unknown function DUF885 SMD44_RS11670 cd402f96ba8656ec99ef430251d2a860 387 Pfam PF02417 Chromate transporter 16 183 9.0E-29 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 SMD44_RS11670 cd402f96ba8656ec99ef430251d2a860 387 Pfam PF02417 Chromate transporter 216 376 8.8E-31 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 SMD44_RS11670 cd402f96ba8656ec99ef430251d2a860 387 TIGRFAM TIGR00937 2A51: chromate efflux transporter 21 358 2.0E-57 T 28-03-2018 IPR014047 Chromate transporter, long chain SMD44_RS11670 cd402f96ba8656ec99ef430251d2a860 387 PIRSF PIRSF004810 5 383 1.2E-69 T 28-03-2018 IPR014047 Chromate transporter, long chain SMD44_RS39100 d4a87139b11f178462406887a7152ed7 141 Pfam PF00011 Hsp20/alpha crystallin family 45 138 1.1E-13 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain SMD44_RS39100 d4a87139b11f178462406887a7152ed7 141 SUPERFAMILY SSF49764 20 128 3.84E-22 T 28-03-2018 IPR008978 HSP20-like chaperone SMD44_RS39100 d4a87139b11f178462406887a7152ed7 141 Gene3D G3DSA:2.60.40.790 27 139 2.8E-21 T 28-03-2018 IPR008978 HSP20-like chaperone SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 Gene3D G3DSA:3.40.50.2300 39 164 1.8E-36 T 28-03-2018 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 Pfam PF00072 Response regulator receiver domain 42 153 8.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 SUPERFAMILY SSF52172 39 171 5.12E-34 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 Gene3D G3DSA:1.10.10.10 165 254 2.2E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 SMART SM00421 188 245 1.4E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 SUPERFAMILY SSF46894 180 251 8.84E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 ProSitePatterns PS00622 LuxR-type HTH domain signature. 205 232 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 SMART SM00448 40 153 2.3E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 Pfam PF00196 Bacterial regulatory proteins, luxR family 190 245 8.8E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 205 221 2.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 221 233 2.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS31560 0e5e408fd2e9d74b5bb1f982448f7f8f 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 205 2.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 Gene3D G3DSA:1.10.10.60 60 113 1.3E-7 T 28-03-2018 SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 SMART SM00342 19 102 3.0E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 SMART SM00871 126 284 2.6E-24 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 Gene3D G3DSA:3.20.80.10 114 284 8.7E-35 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 SUPERFAMILY SSF55136 126 285 2.14E-21 T 28-03-2018 SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 Gene3D G3DSA:1.10.10.60 2 59 1.6E-11 T 28-03-2018 SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 SUPERFAMILY SSF46689 3 53 4.75E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 SUPERFAMILY SSF46689 55 105 6.27E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 Pfam PF06445 GyrI-like small molecule binding domain 126 283 1.2E-22 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain SMD44_RS00960 fdaf3384be491c0717a4615f29b77d92 288 Pfam PF12833 Helix-turn-helix domain 25 103 2.3E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS41030 366d28d7da00a144c6af01f4d43209c6 78 SUPERFAMILY SSF103481 3 35 2.22E-5 T 28-03-2018 SMD44_RS42895 ab402e23c91d490f6071b8aef9809e86 289 Gene3D G3DSA:1.10.260.40 12 95 1.5E-14 T 28-03-2018 SMD44_RS42895 ab402e23c91d490f6071b8aef9809e86 289 SMART SM00530 18 73 4.8E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS42895 ab402e23c91d490f6071b8aef9809e86 289 Pfam PF13560 Helix-turn-helix domain 15 74 5.4E-13 T 28-03-2018 SMD44_RS42895 ab402e23c91d490f6071b8aef9809e86 289 SUPERFAMILY SSF47413 11 73 7.88E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS02985 1de86940a87b1f5b3251eb222d0fbc77 195 SUPERFAMILY SSF52499 15 158 4.06E-37 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS02985 1de86940a87b1f5b3251eb222d0fbc77 195 Gene3D G3DSA:3.40.50.850 2 188 7.8E-38 T 28-03-2018 SMD44_RS02985 1de86940a87b1f5b3251eb222d0fbc77 195 Pfam PF00857 Isochorismatase family 16 153 1.6E-29 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS17850 38703f306f7bc9ca0c0e6f8ea3d05699 289 Pfam PF13569 Domain of unknown function (DUF4132) 30 173 5.9E-17 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 SMD44_RS28125 20d4b938e3abb66e1bddffa25a6798d5 465 Gene3D G3DSA:3.30.200.20 102 239 4.9E-25 T 28-03-2018 SMD44_RS28125 20d4b938e3abb66e1bddffa25a6798d5 465 Pfam PF03109 ABC1 family 113 227 5.8E-31 T 28-03-2018 IPR004147 UbiB domain SMD44_RS28125 20d4b938e3abb66e1bddffa25a6798d5 465 SUPERFAMILY SSF56112 95 158 3.3E-22 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS28125 20d4b938e3abb66e1bddffa25a6798d5 465 SUPERFAMILY SSF56112 195 339 3.3E-22 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS42615 111e6d69f877e91e680b45cdf50b7d53 421 SUPERFAMILY SSF53187 11 301 4.07E-25 T 28-03-2018 SMD44_RS42615 111e6d69f877e91e680b45cdf50b7d53 421 Gene3D G3DSA:3.40.630.10 15 306 6.5E-25 T 28-03-2018 SMD44_RS42615 111e6d69f877e91e680b45cdf50b7d53 421 SMART SM00631 18 291 0.0051 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS42615 111e6d69f877e91e680b45cdf50b7d53 421 Pfam PF00246 Zinc carboxypeptidase 27 284 3.3E-12 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD44_RS25135 b848466700a043a9259f6c5b5a91fd66 342 Pfam PF07452 CHRD domain 74 194 4.8E-19 T 28-03-2018 IPR010895 CHRD SMD44_RS25135 b848466700a043a9259f6c5b5a91fd66 342 SMART SM00754 72 196 3.8E-26 T 28-03-2018 IPR010895 CHRD SMD44_RS25135 b848466700a043a9259f6c5b5a91fd66 342 Pfam PF11937 Protein of unknown function (DUF3455) 247 339 1.4E-11 T 28-03-2018 IPR021851 Protein of unknown function DUF3455 SMD44_RS24455 588918fa8c6e091a25dd64d42fd4931a 511 Gene3D G3DSA:3.40.50.1820 82 497 2.0E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24455 588918fa8c6e091a25dd64d42fd4931a 511 SUPERFAMILY SSF53474 65 149 1.77E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24455 588918fa8c6e091a25dd64d42fd4931a 511 SUPERFAMILY SSF53474 186 468 1.77E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24455 588918fa8c6e091a25dd64d42fd4931a 511 Pfam PF00561 alpha/beta hydrolase fold 103 470 2.4E-32 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS20320 52def44a18de0487bbedf0db15ff22ea 248 Gene3D G3DSA:1.10.10.10 143 247 5.2E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20320 52def44a18de0487bbedf0db15ff22ea 248 SMART SM00862 167 241 4.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS20320 52def44a18de0487bbedf0db15ff22ea 248 Gene3D G3DSA:3.40.50.2300 9 142 4.3E-37 T 28-03-2018 SMD44_RS20320 52def44a18de0487bbedf0db15ff22ea 248 Pfam PF00072 Response regulator receiver domain 22 131 1.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS20320 52def44a18de0487bbedf0db15ff22ea 248 Pfam PF00486 Transcriptional regulatory protein, C terminal 167 240 5.6E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS20320 52def44a18de0487bbedf0db15ff22ea 248 SMART SM00448 20 131 1.9E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS20320 52def44a18de0487bbedf0db15ff22ea 248 SUPERFAMILY SSF52172 18 198 9.96E-41 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS18955 5fd1d9cd060e19101116af81fdd39428 1084 Gene3D G3DSA:2.60.120.380 368 467 0.034 T 28-03-2018 SMD44_RS18955 5fd1d9cd060e19101116af81fdd39428 1084 Gene3D G3DSA:2.60.40.10 814 997 0.0017 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS27175 9e3d11f107f85aef6193b05cbca3771b 831 Gene3D G3DSA:1.25.40.10 201 610 1.3E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS27175 9e3d11f107f85aef6193b05cbca3771b 831 SUPERFAMILY SSF48452 385 580 2.37E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS04915 006146b06ffd3bdc9fec87617d506c44 214 SUPERFAMILY SSF46785 21 194 4.95E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04915 006146b06ffd3bdc9fec87617d506c44 214 Gene3D G3DSA:1.10.10.10 18 109 8.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04915 006146b06ffd3bdc9fec87617d506c44 214 Pfam PF03551 Transcriptional regulator PadR-like family 25 100 5.3E-10 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS08360 3bc69e02c065e903a4987fccaf925cd0 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 1.9E-28 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS20925 a3c5c6057780e08bdb75e2e3645a9aa4 143 Gene3D G3DSA:3.30.450.20 3 125 4.8E-5 T 28-03-2018 SMD44_RS20925 a3c5c6057780e08bdb75e2e3645a9aa4 143 SUPERFAMILY SSF143744 10 141 3.14E-35 T 28-03-2018 SMD44_RS20925 a3c5c6057780e08bdb75e2e3645a9aa4 143 Pfam PF03928 Haem-degrading 13 139 2.0E-29 T 28-03-2018 IPR005624 Haem-degrading SMD44_RS16190 987045be1e75677161d2c6b165664fdc 552 Gene3D G3DSA:3.90.550.10 1 266 1.4E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16190 987045be1e75677161d2c6b165664fdc 552 Pfam PF00535 Glycosyl transferase family 2 3 128 9.4E-32 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS16190 987045be1e75677161d2c6b165664fdc 552 SUPERFAMILY SSF53448 1 214 5.16E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS33165 396249c9eb49100a0bfcf7eb658f4399 561 Pfam PF02449 Beta-galactosidase 207 251 2.9E-4 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD44_RS33165 396249c9eb49100a0bfcf7eb658f4399 561 Gene3D G3DSA:1.10.260.40 21 94 4.1E-7 T 28-03-2018 SMD44_RS33165 396249c9eb49100a0bfcf7eb658f4399 561 SUPERFAMILY SSF51445 196 445 9.29E-28 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS33165 396249c9eb49100a0bfcf7eb658f4399 561 Pfam PF13560 Helix-turn-helix domain 23 86 4.2E-8 T 28-03-2018 SMD44_RS33165 396249c9eb49100a0bfcf7eb658f4399 561 Gene3D G3DSA:3.20.20.80 192 448 1.9E-19 T 28-03-2018 SMD44_RS06365 03203f29d47e95b564a367f258f3abb8 140 Pfam PF03995 Peptidase inhibitor family I36 41 110 8.8E-14 T 28-03-2018 SMD44_RS06365 03203f29d47e95b564a367f258f3abb8 140 Gene3D G3DSA:2.60.20.10 38 139 5.0E-7 T 28-03-2018 SMD44_RS00305 cfe121f77b2a46bedc692a6a7b5e5172 419 SUPERFAMILY SSF102114 122 336 5.23E-7 T 28-03-2018 SMD44_RS00305 cfe121f77b2a46bedc692a6a7b5e5172 419 Gene3D G3DSA:3.20.20.70 100 340 2.4E-7 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS09180 cbe64d1ee43bccb766a919f09014f2dd 115 Pfam PF02036 SCP-2 sterol transfer family 21 109 1.1E-6 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS09180 cbe64d1ee43bccb766a919f09014f2dd 115 Gene3D G3DSA:3.30.1050.10 1 115 3.1E-18 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS09180 cbe64d1ee43bccb766a919f09014f2dd 115 SUPERFAMILY SSF55718 9 115 4.0E-15 T 28-03-2018 IPR003033 SCP2 sterol-binding domain SMD44_RS35250 09dabcdaf67e2440701531cfcbe658e7 407 Pfam PF16483 Beta-1,3-glucanase 37 405 1.6E-114 T 28-03-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 SMD44_RS16575 43f05b1c48233d999c7b1fa9e5d929a9 313 Gene3D G3DSA:3.40.50.1820 4 313 3.6E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS16575 43f05b1c48233d999c7b1fa9e5d929a9 313 Pfam PF07859 alpha/beta hydrolase fold 82 285 1.3E-12 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMD44_RS16575 43f05b1c48233d999c7b1fa9e5d929a9 313 SUPERFAMILY SSF53474 32 303 3.02E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS11865 2b4872c62e660f7c11ecc96da516107d 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 125 7.2E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS11865 2b4872c62e660f7c11ecc96da516107d 144 SUPERFAMILY SSF54593 7 130 2.01E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS11865 2b4872c62e660f7c11ecc96da516107d 144 Gene3D G3DSA:3.10.180.10 1 140 2.4E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS10370 d3240902d619efa6d4ce6fc3ee372709 378 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 87 232 1.7E-13 T 28-03-2018 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent SMD44_RS10370 d3240902d619efa6d4ce6fc3ee372709 378 SUPERFAMILY SSF51695 65 251 1.26E-13 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS10370 d3240902d619efa6d4ce6fc3ee372709 378 Gene3D G3DSA:3.20.20.190 60 291 2.7E-15 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS32380 8978e684e099d84e569700fb2ea81875 199 Pfam PF11452 Protein of unknown function (DUF3000) 7 180 8.4E-71 T 28-03-2018 IPR021555 Protein of unknown function DUF3000 SMD44_RS11165 2988646b119f4903a07513039aeb7bc8 73 Pfam PF02597 ThiS family 10 73 7.9E-18 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMD44_RS11165 2988646b119f4903a07513039aeb7bc8 73 SUPERFAMILY SSF54285 10 72 6.54E-17 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMD44_RS11165 2988646b119f4903a07513039aeb7bc8 73 Gene3D G3DSA:3.10.20.30 9 73 8.9E-25 T 28-03-2018 IPR012675 Beta-grasp domain SMD44_RS11165 2988646b119f4903a07513039aeb7bc8 73 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 10 73 2.1E-22 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 306 7.4E-120 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 3.1E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 Gene3D G3DSA:3.40.50.720 145 319 6.2E-29 T 28-03-2018 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 8.4E-36 T 28-03-2018 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 8.4E-36 T 28-03-2018 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 8.4E-36 T 28-03-2018 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 8.4E-36 T 28-03-2018 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 8.4E-36 T 28-03-2018 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 Gene3D G3DSA:3.50.50.60 2 135 4.7E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 SUPERFAMILY SSF51905 5 305 7.66E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS21065 11b000214ab31465a270fb5ae8744ec5 320 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 5.3E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS23755 e42f960ef4262cff79e096400d1c5bd7 246 SUPERFAMILY SSF161098 23 206 2.22E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS23755 e42f960ef4262cff79e096400d1c5bd7 246 Gene3D G3DSA:1.10.3720.10 17 221 2.3E-27 T 28-03-2018 SMD44_RS23755 e42f960ef4262cff79e096400d1c5bd7 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 220 1.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS25085 daab92a78f5c40c9450de20f51ef29f2 549 Pfam PF00361 Proton-conducting membrane transporter 179 485 9.5E-73 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25085 daab92a78f5c40c9450de20f51ef29f2 549 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 152 537 1.6E-113 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMD44_RS25085 daab92a78f5c40c9450de20f51ef29f2 549 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 25 538 17.894 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMD44_RS30080 28eb474162118c0bcf4f2198f4d1cfb2 412 Gene3D G3DSA:2.130.10.10 250 402 4.7E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS30080 28eb474162118c0bcf4f2198f4d1cfb2 412 Gene3D G3DSA:2.120.10.60 27 249 5.0E-7 T 28-03-2018 SMD44_RS30080 28eb474162118c0bcf4f2198f4d1cfb2 412 Pfam PF07676 WD40-like Beta Propeller Repeat 263 283 0.021 T 28-03-2018 IPR011659 WD40-like Beta Propeller SMD44_RS30080 28eb474162118c0bcf4f2198f4d1cfb2 412 SUPERFAMILY SSF82171 74 391 1.28E-16 T 28-03-2018 SMD44_RS10540 a1236db40627bf3c130bf6f72e72debe 580 Pfam PF02653 Branched-chain amino acid transport system / permease component 253 537 5.2E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS10540 a1236db40627bf3c130bf6f72e72debe 580 Gene3D G3DSA:1.10.3470.10 191 540 1.9E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS18825 a9470de9c4b0a08b9e2ed6ad005f27cc 96 Pfam PF11662 Protein of unknown function (DUF3263) 24 96 1.4E-30 T 28-03-2018 IPR021678 Protein of unknown function DUF3263 SMD44_RS34940 cf62ada0d93af92b89bb9f5d1ac76787 438 SUPERFAMILY SSF53720 268 412 6.05E-8 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS34940 cf62ada0d93af92b89bb9f5d1ac76787 438 SUPERFAMILY SSF53720 156 240 6.05E-8 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS34940 cf62ada0d93af92b89bb9f5d1ac76787 438 Gene3D G3DSA:3.40.309.10 263 425 6.8E-5 T 28-03-2018 SMD44_RS34940 cf62ada0d93af92b89bb9f5d1ac76787 438 Gene3D G3DSA:3.40.980.10 70 153 0.0034 T 28-03-2018 IPR001453 MoaB/Mog domain SMD44_RS15510 f3703a7c04fb372bd668967d32a7cfc2 281 Pfam PF13560 Helix-turn-helix domain 11 72 2.9E-16 T 28-03-2018 SMD44_RS15510 f3703a7c04fb372bd668967d32a7cfc2 281 SMART SM00530 15 70 9.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS15510 f3703a7c04fb372bd668967d32a7cfc2 281 Gene3D G3DSA:1.10.3100.10 6 159 6.3E-16 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS15510 f3703a7c04fb372bd668967d32a7cfc2 281 SUPERFAMILY SSF47413 9 66 4.83E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS15725 a9fc204a6159655720cc1bec26d3576b 238 Pfam PF06271 RDD family 95 231 2.5E-27 T 28-03-2018 IPR010432 RDD SMD44_RS12515 8a95879ba98ebf770aede346adb3f6e4 218 Gene3D G3DSA:3.40.50.1000 84 210 8.0E-23 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS12515 8a95879ba98ebf770aede346adb3f6e4 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 88 185 3.0E-17 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD44_RS12515 8a95879ba98ebf770aede346adb3f6e4 218 ProSitePatterns PS01228 Hypothetical cof family signature 1. 11 22 - T 28-03-2018 SMD44_RS12515 8a95879ba98ebf770aede346adb3f6e4 218 Gene3D G3DSA:1.10.150.240 41 83 4.6E-17 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD44_RS12515 8a95879ba98ebf770aede346adb3f6e4 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 185 4.3E-20 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS12515 8a95879ba98ebf770aede346adb3f6e4 218 Gene3D G3DSA:3.40.50.1000 4 40 0.13 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS12515 8a95879ba98ebf770aede346adb3f6e4 218 SUPERFAMILY SSF56784 10 204 7.07E-43 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS08070 d052b4a70ade508e1773650476ed1982 526 SUPERFAMILY SSF55874 238 361 7.74E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS08070 d052b4a70ade508e1773650476ed1982 526 Gene3D G3DSA:3.30.565.10 115 357 2.8E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS08070 d052b4a70ade508e1773650476ed1982 526 SMART SM00387 245 359 6.1E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 Gene3D G3DSA:1.10.240.10 225 325 1.9E-32 T 28-03-2018 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 SUPERFAMILY SSF52374 3 324 2.25E-100 T 28-03-2018 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 419 44.706 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 Gene3D G3DSA:3.10.290.10 326 421 9.6E-23 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 Gene3D G3DSA:3.40.50.620 2 224 1.9E-65 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 2.7E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 2.7E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 2.7E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 2.7E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 Pfam PF00579 tRNA synthetases class I (W and Y) 30 324 3.6E-79 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 419 2.0E-114 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD44_RS09385 f79e643fbd93e006309072ad0d2e32dc 421 SUPERFAMILY SSF55174 327 418 3.53E-15 T 28-03-2018 SMD44_RS06220 b9fdadd5cd8bdb15ae2bacf1c1e63bb9 407 Gene3D G3DSA:3.90.420.10 252 407 8.2E-33 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS06220 b9fdadd5cd8bdb15ae2bacf1c1e63bb9 407 Pfam PF00174 Oxidoreductase molybdopterin binding domain 271 404 1.4E-22 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS06220 b9fdadd5cd8bdb15ae2bacf1c1e63bb9 407 SUPERFAMILY SSF56524 260 405 9.81E-33 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS06220 b9fdadd5cd8bdb15ae2bacf1c1e63bb9 407 Gene3D G3DSA:1.20.950.20 1 171 1.3E-6 T 28-03-2018 SMD44_RS18785 4fdbf43f0ed69978882a71dad5399454 165 SUPERFAMILY SSF88659 99 155 9.59E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18785 4fdbf43f0ed69978882a71dad5399454 165 SUPERFAMILY SSF88946 4 78 1.26E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18785 4fdbf43f0ed69978882a71dad5399454 165 Gene3D G3DSA:1.10.10.10 97 159 4.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18785 4fdbf43f0ed69978882a71dad5399454 165 Pfam PF08281 Sigma-70, region 4 100 150 9.5E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18785 4fdbf43f0ed69978882a71dad5399454 165 Pfam PF04542 Sigma-70 region 2 10 76 7.8E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS18785 4fdbf43f0ed69978882a71dad5399454 165 Gene3D G3DSA:1.10.1740.10 2 79 1.0E-16 T 28-03-2018 SMD44_RS18785 4fdbf43f0ed69978882a71dad5399454 165 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 2 155 4.1E-44 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD44_RS18785 4fdbf43f0ed69978882a71dad5399454 165 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 31 62 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD44_RS21955 b897628133803a974c56479296901a4e 146 SUPERFAMILY SSF54593 9 146 3.59E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS21955 b897628133803a974c56479296901a4e 146 Gene3D G3DSA:3.10.180.10 7 146 1.2E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS05600 97a5a6099e5780bcc8b68c86461aaea8 242 SUPERFAMILY SSF52317 23 213 4.43E-19 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS05600 97a5a6099e5780bcc8b68c86461aaea8 242 Gene3D G3DSA:3.40.50.880 15 230 2.9E-15 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS05600 97a5a6099e5780bcc8b68c86461aaea8 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 9 202 9.5E-37 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SMD44_RS10835 cb5e11a32955b8d34ec181c6d150419a 136 Pfam PF01042 Endoribonuclease L-PSP 21 126 9.1E-14 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS10835 cb5e11a32955b8d34ec181c6d150419a 136 Gene3D G3DSA:3.30.1330.40 6 127 1.4E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS10835 cb5e11a32955b8d34ec181c6d150419a 136 SUPERFAMILY SSF55298 5 127 6.75E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS22260 e695f419bea490b7cd3009cb541fbaef 115 Pfam PF13411 MerR HTH family regulatory protein 19 80 9.0E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS22260 e695f419bea490b7cd3009cb541fbaef 115 Gene3D G3DSA:1.10.1660.10 10 109 2.8E-15 T 28-03-2018 SMD44_RS22260 e695f419bea490b7cd3009cb541fbaef 115 SUPERFAMILY SSF46955 19 101 7.33E-11 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS22260 e695f419bea490b7cd3009cb541fbaef 115 SMART SM00422 19 87 9.3E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS16465 6e21870705a4fb6b230ffc90b38b8e10 250 SUPERFAMILY SSF56801 4 247 2.75E-20 T 28-03-2018 SMD44_RS16465 6e21870705a4fb6b230ffc90b38b8e10 250 Gene3D G3DSA:3.40.50.980 3 113 7.0E-14 T 28-03-2018 SMD44_RS16465 6e21870705a4fb6b230ffc90b38b8e10 250 Pfam PF00501 AMP-binding enzyme 18 90 2.1E-5 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD44_RS16465 6e21870705a4fb6b230ffc90b38b8e10 250 Gene3D G3DSA:3.40.50.980 166 249 1.6E-4 T 28-03-2018 SMD44_RS16465 6e21870705a4fb6b230ffc90b38b8e10 250 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 246 1.2E-84 T 28-03-2018 IPR017523 Conserved hypothetical protein CHP03089 SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 Gene3D G3DSA:1.20.1250.20 40 230 7.8E-25 T 28-03-2018 SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 Pfam PF07690 Major Facilitator Superfamily 46 433 5.2E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 Gene3D G3DSA:1.20.1250.20 289 497 9.8E-20 T 28-03-2018 SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 191 215 5.7E-8 T 28-03-2018 SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 166 190 5.7E-8 T 28-03-2018 SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 431 450 5.7E-8 T 28-03-2018 SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 156 5.7E-8 T 28-03-2018 SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 SUPERFAMILY SSF103473 278 483 1.96E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS32240 dfe1d3c592c4766b35b0f192b18a7cdd 500 SUPERFAMILY SSF103473 28 225 1.96E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS34340 85bd8b749326b29eb3592806ed2297d6 111 PIRSF PIRSF028743 1 106 3.2E-37 T 28-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMD44_RS34340 85bd8b749326b29eb3592806ed2297d6 111 Pfam PF05800 Gas vesicle synthesis protein GvpO 14 104 2.9E-35 T 28-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMD44_RS11625 0889cd28776f41b2e3cc31c3b3b00cc2 155 PIRSF PIRSF021697 3 155 2.0E-51 T 28-03-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane SMD44_RS11625 0889cd28776f41b2e3cc31c3b3b00cc2 155 Pfam PF06271 RDD family 43 148 9.2E-14 T 28-03-2018 IPR010432 RDD SMD44_RS00925 f0c07f530144b80fb39667330e852903 190 SUPERFAMILY SSF46689 17 76 6.67E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS00925 f0c07f530144b80fb39667330e852903 190 Gene3D G3DSA:1.10.10.60 1 70 3.7E-10 T 28-03-2018 SMD44_RS00925 f0c07f530144b80fb39667330e852903 190 SUPERFAMILY SSF48498 84 188 1.78E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS00925 f0c07f530144b80fb39667330e852903 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 186 2.2E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS00925 f0c07f530144b80fb39667330e852903 190 Gene3D G3DSA:1.10.357.10 71 189 4.4E-15 T 28-03-2018 SMD44_RS28430 f42f8fccc5582f4edcd8cd6ce70cd271 532 Pfam PF00999 Sodium/hydrogen exchanger family 8 402 1.6E-62 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD44_RS28430 f42f8fccc5582f4edcd8cd6ce70cd271 532 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 6 524 5.6E-104 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 SMD44_RS12645 d19e44955810482e794f9629ec76272e 309 SUPERFAMILY SSF53613 7 297 2.49E-70 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS12645 d19e44955810482e794f9629ec76272e 309 Pfam PF00294 pfkB family carbohydrate kinase 10 293 7.6E-49 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS12645 d19e44955810482e794f9629ec76272e 309 Gene3D G3DSA:3.40.1190.20 3 300 3.1E-58 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS10465 391d9f231864b842fe2e48eb0b7cf6a3 133 Gene3D G3DSA:1.25.40.10 81 122 5.9E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS10465 391d9f231864b842fe2e48eb0b7cf6a3 133 Gene3D G3DSA:1.25.40.10 13 80 2.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS10465 391d9f231864b842fe2e48eb0b7cf6a3 133 SUPERFAMILY SSF48452 6 113 8.41E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS10465 391d9f231864b842fe2e48eb0b7cf6a3 133 SMART SM00028 77 110 0.19 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS10465 391d9f231864b842fe2e48eb0b7cf6a3 133 SMART SM00028 43 76 60.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMD44_RS10465 391d9f231864b842fe2e48eb0b7cf6a3 133 Pfam PF14559 Tetratricopeptide repeat 19 76 4.2E-7 T 28-03-2018 SMD44_RS20600 5ec7d2ad8137837dd2399ccdb6ccee88 280 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 271 1.3E-44 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD44_RS20600 5ec7d2ad8137837dd2399ccdb6ccee88 280 Gene3D G3DSA:3.20.20.190 7 278 5.3E-75 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS20600 5ec7d2ad8137837dd2399ccdb6ccee88 280 SUPERFAMILY SSF51695 8 275 1.52E-66 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD44_RS40000 76aaae4824b1a2c31299328078af7ed7 141 SUPERFAMILY SSF53850 2 136 1.99E-17 T 28-03-2018 SMD44_RS40000 76aaae4824b1a2c31299328078af7ed7 141 Gene3D G3DSA:3.10.105.10 1 112 2.7E-17 T 28-03-2018 SMD44_RS23015 d17f31a60baba32f3aec8ec0597712d2 251 Pfam PF01061 ABC-2 type transporter 7 206 6.1E-9 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS13235 3a4ff933d753c4f1f08a392b77e47618 333 Pfam PF07070 SpoOM protein 3 217 1.1E-73 T 28-03-2018 IPR009776 Sporulation stage 0, protein M SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 282 1.5E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 Gene3D G3DSA:3.50.50.60 135 231 4.7E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 SUPERFAMILY SSF51905 5 299 2.59E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 7.8E-13 T 28-03-2018 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 7.8E-13 T 28-03-2018 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 7.8E-13 T 28-03-2018 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.8E-13 T 28-03-2018 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 4.2E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 4.2E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 4.2E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 4.2E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD44_RS04050 cae6b2a883af6e506738a8aa2c424125 346 Gene3D G3DSA:3.50.50.60 1 134 2.0E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS12205 91b021a8434fce280b0c03d7f023d131 268 SUPERFAMILY SSF46955 1 109 3.66E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS12205 91b021a8434fce280b0c03d7f023d131 268 SMART SM00422 1 70 4.8E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS12205 91b021a8434fce280b0c03d7f023d131 268 Pfam PF00376 MerR family regulatory protein 2 39 4.1E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS12205 91b021a8434fce280b0c03d7f023d131 268 Gene3D G3DSA:1.10.1660.10 58 124 2.8E-6 T 28-03-2018 SMD44_RS12205 91b021a8434fce280b0c03d7f023d131 268 Gene3D G3DSA:1.10.1660.10 1 57 2.2E-18 T 28-03-2018 SMD44_RS22905 4bce30333e05470daece24688d57255c 166 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 32 161 6.7E-13 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMD44_RS22905 4bce30333e05470daece24688d57255c 166 Gene3D G3DSA:3.30.530.20 21 166 9.3E-23 T 28-03-2018 IPR023393 START-like domain SMD44_RS22905 4bce30333e05470daece24688d57255c 166 SUPERFAMILY SSF55961 23 162 5.27E-23 T 28-03-2018 SMD44_RS33990 6c5ed5ad8e31e47b243a9a2e03806d5f 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 260 1.9E-65 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS33990 6c5ed5ad8e31e47b243a9a2e03806d5f 280 Gene3D G3DSA:3.60.110.10 4 276 1.0E-75 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS33990 6c5ed5ad8e31e47b243a9a2e03806d5f 280 SUPERFAMILY SSF56317 3 279 6.54E-80 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS39620 abe281e83f164e86eac7f2ffe2d76e86 231 Gene3D G3DSA:3.40.630.30 3 194 4.5E-19 T 28-03-2018 SMD44_RS39620 abe281e83f164e86eac7f2ffe2d76e86 231 SUPERFAMILY SSF55729 14 178 2.9E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS39620 abe281e83f164e86eac7f2ffe2d76e86 231 Pfam PF13302 Acetyltransferase (GNAT) domain 23 148 1.8E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS07300 a957f34b8fd05e2c3f99d5d24cf5db31 368 SUPERFAMILY SSF55920 137 366 2.88E-58 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS07300 a957f34b8fd05e2c3f99d5d24cf5db31 368 Gene3D G3DSA:3.40.350.10 3 136 9.3E-16 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMD44_RS07300 a957f34b8fd05e2c3f99d5d24cf5db31 368 SUPERFAMILY SSF53092 5 137 9.24E-19 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMD44_RS07300 a957f34b8fd05e2c3f99d5d24cf5db31 368 Gene3D G3DSA:3.90.230.10 137 368 1.7E-56 T 28-03-2018 SMD44_RS07300 a957f34b8fd05e2c3f99d5d24cf5db31 368 Pfam PF00557 Metallopeptidase family M24 146 348 2.7E-45 T 28-03-2018 IPR000994 Peptidase M24 SMD44_RS07300 a957f34b8fd05e2c3f99d5d24cf5db31 368 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 138 1.0E-11 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 SMD44_RS11470 fe9e840fe74bbc734533f0c9f6e2ecf9 233 Gene3D G3DSA:3.40.50.150 3 233 5.1E-33 T 28-03-2018 SMD44_RS11470 fe9e840fe74bbc734533f0c9f6e2ecf9 233 SUPERFAMILY SSF53335 8 146 1.67E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS11470 fe9e840fe74bbc734533f0c9f6e2ecf9 233 Pfam PF08241 Methyltransferase domain 23 123 2.0E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS10205 a691fd079f3923516ddf429113e8479c 218 Pfam PF00753 Metallo-beta-lactamase superfamily 29 178 1.6E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS10205 a691fd079f3923516ddf429113e8479c 218 SMART SM00849 32 197 2.5E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS10205 a691fd079f3923516ddf429113e8479c 218 Gene3D G3DSA:3.60.15.10 15 216 4.5E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS10205 a691fd079f3923516ddf429113e8479c 218 SUPERFAMILY SSF56281 22 214 9.48E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS20335 8c41b4c8b02d0d27014423934a05559f 308 Pfam PF10977 Protein of unknown function (DUF2797) 38 272 1.4E-26 T 28-03-2018 IPR021246 Protein of unknown function DUF2797 SMD44_RS00930 efefbb46f2c5f7db7f4e8dc00218f2ae 241 Gene3D G3DSA:3.10.520.10 4 241 1.9E-59 T 28-03-2018 SMD44_RS00930 efefbb46f2c5f7db7f4e8dc00218f2ae 241 SUPERFAMILY SSF143631 4 237 4.18E-59 T 28-03-2018 IPR003374 ApbE-like domain SMD44_RS00930 efefbb46f2c5f7db7f4e8dc00218f2ae 241 Pfam PF02424 ApbE family 93 222 6.9E-36 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SMD44_RS00930 efefbb46f2c5f7db7f4e8dc00218f2ae 241 Pfam PF02424 ApbE family 8 88 1.4E-11 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SMD44_RS19400 b3f70b84106fc38f05887b959988cada 332 Pfam PF01384 Phosphate transporter family 20 320 2.2E-87 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMD44_RS26765 2ee250f7fc925ca3159dffb409c64e30 360 Gene3D G3DSA:3.40.50.2300 168 358 3.9E-39 T 28-03-2018 SMD44_RS26765 2ee250f7fc925ca3159dffb409c64e30 360 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 58 344 7.1E-54 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 SMD44_RS26765 2ee250f7fc925ca3159dffb409c64e30 360 Gene3D G3DSA:3.40.50.2300 50 167 3.1E-34 T 28-03-2018 SMD44_RS26765 2ee250f7fc925ca3159dffb409c64e30 360 SUPERFAMILY SSF53822 64 311 3.34E-12 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS35260 696416b6fbe4a78abc41b18c6533f01b 82 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 82 17.38 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS35260 696416b6fbe4a78abc41b18c6533f01b 82 Pfam PF02467 Transcription factor WhiB 14 77 1.4E-24 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS17270 1c4df2419decdb9643019b6fa0d65f28 282 Gene3D G3DSA:3.30.2140.10 4 151 3.6E-37 T 28-03-2018 SMD44_RS17270 1c4df2419decdb9643019b6fa0d65f28 282 Pfam PF00797 N-acetyltransferase 25 272 3.1E-48 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD44_RS17270 1c4df2419decdb9643019b6fa0d65f28 282 SUPERFAMILY SSF54001 5 276 7.46E-62 T 28-03-2018 SMD44_RS17270 1c4df2419decdb9643019b6fa0d65f28 282 Gene3D G3DSA:3.30.2140.10 152 281 2.7E-13 T 28-03-2018 SMD44_RS29070 c67fda6140f8801751140500d24304e6 212 Pfam PF01987 Mitochondrial biogenesis AIM24 5 202 2.2E-31 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS29070 c67fda6140f8801751140500d24304e6 212 SUPERFAMILY SSF51219 8 209 1.41E-43 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD44_RS29070 c67fda6140f8801751140500d24304e6 212 Gene3D G3DSA:3.60.160.10 2 212 1.1E-40 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS19460 94c063897032018442cf1ec0777ff4ce 156 SUPERFAMILY SSF52218 1 148 8.54E-17 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS19460 94c063897032018442cf1ec0777ff4ce 156 Pfam PF12724 Flavodoxin domain 11 68 7.2E-9 T 28-03-2018 IPR026816 Flavodoxin domain SMD44_RS19460 94c063897032018442cf1ec0777ff4ce 156 Gene3D G3DSA:3.40.50.360 2 151 1.4E-14 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS40370 f34a11c008785259f4308389eb0c9f6c 230 Gene3D G3DSA:3.50.40.10 57 212 3.1E-26 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMD44_RS40370 f34a11c008785259f4308389eb0c9f6c 230 SMART SM00873 59 213 1.5E-9 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD44_RS40370 f34a11c008785259f4308389eb0c9f6c 230 Pfam PF03483 B3/4 domain 60 193 2.2E-22 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD44_RS40370 f34a11c008785259f4308389eb0c9f6c 230 SUPERFAMILY SSF56037 51 221 3.14E-31 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMD44_RS14730 ec6b546ac2cf79075e98b816bd976677 327 Gene3D G3DSA:3.40.1190.20 15 326 2.5E-84 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS14730 ec6b546ac2cf79075e98b816bd976677 327 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 15 320 1.1E-114 T 28-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 SMD44_RS14730 ec6b546ac2cf79075e98b816bd976677 327 SUPERFAMILY SSF53613 14 320 7.02E-74 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS14730 ec6b546ac2cf79075e98b816bd976677 327 Pfam PF00294 pfkB family carbohydrate kinase 17 312 4.4E-50 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 Gene3D G3DSA:3.90.45.10 4 176 7.5E-42 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 SUPERFAMILY SSF56420 4 158 6.8E-35 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 PRINTS PR01576 Peptide deformylase signature 110 128 1.9E-17 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 PRINTS PR01576 Peptide deformylase signature 42 71 1.9E-17 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 PRINTS PR01576 Peptide deformylase signature 98 109 1.9E-17 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 PRINTS PR01576 Peptide deformylase signature 129 158 1.9E-17 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 Hamap MF_00163 Peptide deformylase [def]. 2 171 19.921 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 Pfam PF01327 Polypeptide deformylase 6 157 2.3E-31 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS00090 ff9f6e88c897453a930176ba51df23c7 179 PIRSF PIRSF004749 1 176 3.7E-29 T 28-03-2018 IPR023635 Peptide deformylase SMD44_RS28695 cdbd997241cd1c71b5645982b5270c14 312 Gene3D G3DSA:1.10.620.20 11 289 3.9E-33 T 28-03-2018 SMD44_RS28695 cdbd997241cd1c71b5645982b5270c14 312 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 21 295 1.1E-99 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF SMD44_RS28695 cdbd997241cd1c71b5645982b5270c14 312 SUPERFAMILY SSF47240 37 225 3.12E-12 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS43615 84fcfbf41cd37a8ab0bb7ad316e12538 164 Gene3D G3DSA:1.10.260.40 10 102 1.3E-4 T 28-03-2018 SMD44_RS36375 0fc924ee3cb4c7282937cc436c34d761 186 SUPERFAMILY SSF55729 9 180 2.7E-42 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS36375 0fc924ee3cb4c7282937cc436c34d761 186 Pfam PF13302 Acetyltransferase (GNAT) domain 12 156 1.2E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS36375 0fc924ee3cb4c7282937cc436c34d761 186 Gene3D G3DSA:3.40.630.30 5 186 3.3E-31 T 28-03-2018 SMD44_RS20985 039e4faa5abc631a0c03d0ef4b748033 96 Gene3D G3DSA:3.30.70.60 1 96 1.4E-28 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 SMD44_RS20985 039e4faa5abc631a0c03d0ef4b748033 96 Pfam PF01250 Ribosomal protein S6 3 92 1.4E-28 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20985 039e4faa5abc631a0c03d0ef4b748033 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 22.051 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD44_RS20985 039e4faa5abc631a0c03d0ef4b748033 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 28-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD44_RS20985 039e4faa5abc631a0c03d0ef4b748033 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 3.7E-26 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS20985 039e4faa5abc631a0c03d0ef4b748033 96 SUPERFAMILY SSF54995 1 94 4.45E-32 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD44_RS14225 e2cda50457322004c53bf4354a83e9ed 487 ProSitePatterns PS00218 Amino acid permeases signature. 65 95 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD44_RS14225 e2cda50457322004c53bf4354a83e9ed 487 PIRSF PIRSF006060 14 486 1.0E-70 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS14225 e2cda50457322004c53bf4354a83e9ed 487 Pfam PF00324 Amino acid permease 40 453 6.1E-114 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD44_RS19755 899f68704885bf187008a37549b682a7 336 SUPERFAMILY SSF46785 11 91 6.69E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19755 899f68704885bf187008a37549b682a7 336 PIRSF PIRSF005739 9 332 4.6E-36 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD44_RS19755 899f68704885bf187008a37549b682a7 336 Gene3D G3DSA:1.10.10.10 11 88 1.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19755 899f68704885bf187008a37549b682a7 336 SUPERFAMILY SSF53335 92 331 1.49E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS19755 899f68704885bf187008a37549b682a7 336 Gene3D G3DSA:3.40.50.150 89 333 2.3E-42 T 28-03-2018 SMD44_RS19755 899f68704885bf187008a37549b682a7 336 Pfam PF00891 O-methyltransferase 103 314 1.3E-38 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD44_RS19755 899f68704885bf187008a37549b682a7 336 Pfam PF16864 Dimerisation domain 12 74 5.8E-8 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain SMD44_RS12685 c304a91615e6c92269e2ebcc4879b6b3 191 Pfam PF02342 TerD domain 1 186 2.4E-81 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS12685 c304a91615e6c92269e2ebcc4879b6b3 191 Gene3D G3DSA:2.60.60.30 18 184 1.4E-65 T 28-03-2018 SMD44_RS22995 e5417a0bceefd5b1ff5579166626ac21 200 SUPERFAMILY SSF53254 2 188 4.99E-40 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS22995 e5417a0bceefd5b1ff5579166626ac21 200 Gene3D G3DSA:3.40.50.1240 1 192 3.6E-38 T 28-03-2018 IPR029033 Histidine phosphatase superfamily SMD44_RS22995 e5417a0bceefd5b1ff5579166626ac21 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 173 6.6E-36 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS22995 e5417a0bceefd5b1ff5579166626ac21 200 PIRSF PIRSF000709 2 167 8.2E-6 T 28-03-2018 SMD44_RS22995 e5417a0bceefd5b1ff5579166626ac21 200 SMART SM00855 2 156 1.1E-16 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMD44_RS21755 b52d55d66294994680546e7aa1d83c07 371 Gene3D G3DSA:3.40.50.720 135 262 1.3E-26 T 28-03-2018 SMD44_RS21755 b52d55d66294994680546e7aa1d83c07 371 Pfam PF02254 TrkA-N domain 146 262 5.3E-28 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD44_RS21755 b52d55d66294994680546e7aa1d83c07 371 Pfam PF07885 Ion channel 42 125 1.9E-13 T 28-03-2018 IPR013099 Potassium channel domain SMD44_RS21755 b52d55d66294994680546e7aa1d83c07 371 Gene3D G3DSA:1.10.287.70 33 134 7.7E-15 T 28-03-2018 SMD44_RS21755 b52d55d66294994680546e7aa1d83c07 371 SUPERFAMILY SSF51735 141 279 1.56E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21755 b52d55d66294994680546e7aa1d83c07 371 SUPERFAMILY SSF81324 33 164 1.31E-19 T 28-03-2018 SMD44_RS07885 f1f98e943e18a19aa074ce0cb704bc24 449 SUPERFAMILY SSF48452 218 408 2.72E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS07885 f1f98e943e18a19aa074ce0cb704bc24 449 Gene3D G3DSA:1.25.40.10 101 437 1.4E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS12555 99e908482d2c5ec534070bb61bfad8d0 74 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 69 3.6E-28 T 28-03-2018 IPR018735 Protein of unknown function DUF2277 SMD44_RS26980 7f69c30dd04ba96bbaeaedeb80305737 68 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 1 61 5.1E-17 T 28-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 Gene3D G3DSA:3.40.50.1370 1 169 2.5E-61 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 147 1.4E-43 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 6.4E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 6.4E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 6.4E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 6.4E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 312 41.453 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00101 Aspartate carbamoyltransferase signature 267 272 1.2E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00101 Aspartate carbamoyltransferase signature 291 305 1.2E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.2E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.2E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.2E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 1.2E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 309 5.2E-23 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 Gene3D G3DSA:3.40.50.1370 170 312 3.1E-45 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 310 9.1E-92 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMD44_RS07275 b2cede15b81690f3fc669527b5678ebd 337 SUPERFAMILY SSF53671 1 312 1.02E-93 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD44_RS05905 80f017e293ce12bc51eae5625bf308b4 143 SUPERFAMILY SSF55961 4 136 2.2E-30 T 28-03-2018 SMD44_RS05905 80f017e293ce12bc51eae5625bf308b4 143 Gene3D G3DSA:3.30.530.20 2 142 2.4E-26 T 28-03-2018 IPR023393 START-like domain SMD44_RS05905 80f017e293ce12bc51eae5625bf308b4 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 136 1.2E-18 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS33525 99882fff81002946d0edae767f4d530c 207 SUPERFAMILY SSF53448 16 204 2.7E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS33525 99882fff81002946d0edae767f4d530c 207 Gene3D G3DSA:3.90.550.10 14 200 1.1E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS33525 99882fff81002946d0edae767f4d530c 207 Pfam PF12804 MobA-like NTP transferase domain 18 179 6.4E-35 T 28-03-2018 IPR025877 MobA-like NTP transferase SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 SMART SM00191 25 104 24.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 SMART SM00191 342 404 4.6E-9 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 SMART SM00191 116 164 13.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 SMART SM00191 271 329 0.066 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 SMART SM00191 170 237 43.0 T 28-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 SUPERFAMILY SSF69318 46 438 5.49E-53 T 28-03-2018 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 Gene3D G3DSA:2.60.40.680 145 201 8.6E-6 T 28-03-2018 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 Gene3D G3DSA:2.60.40.680 17 144 8.6E-17 T 28-03-2018 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 Gene3D G3DSA:2.60.40.680 211 362 4.3E-19 T 28-03-2018 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 Gene3D G3DSA:2.60.40.680 363 445 2.8E-11 T 28-03-2018 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 128 193 4.2E-9 T 28-03-2018 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 Pfam PF01839 FG-GAP repeat 346 369 9.2E-8 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 Pfam PF01839 FG-GAP repeat 49 76 4.2E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS02325 93212585b6c208c429ec7f5582cffdac 486 Pfam PF01839 FG-GAP repeat 275 295 3.7E-6 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMD44_RS33455 9dff5ed7b8e60516a7a9e1ee21d36914 307 SUPERFAMILY SSF51430 26 301 2.88E-66 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS33455 9dff5ed7b8e60516a7a9e1ee21d36914 307 Pfam PF00248 Aldo/keto reductase family 36 233 2.5E-33 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS33455 9dff5ed7b8e60516a7a9e1ee21d36914 307 Pfam PF00248 Aldo/keto reductase family 242 300 5.0E-10 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS33455 9dff5ed7b8e60516a7a9e1ee21d36914 307 PRINTS PR00069 Aldo-keto reductase signature 164 181 3.4E-10 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS33455 9dff5ed7b8e60516a7a9e1ee21d36914 307 PRINTS PR00069 Aldo-keto reductase signature 236 260 3.4E-10 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS33455 9dff5ed7b8e60516a7a9e1ee21d36914 307 PRINTS PR00069 Aldo-keto reductase signature 66 90 3.4E-10 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD44_RS33455 9dff5ed7b8e60516a7a9e1ee21d36914 307 Gene3D G3DSA:3.20.20.100 20 303 5.9E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 9.3E-32 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 SUPERFAMILY SSF50249 1 66 1.14E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 PIRSF PIRSF002599 1 67 5.2E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 PRINTS PR00050 Cold shock protein signature 25 34 6.3E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 PRINTS PR00050 Cold shock protein signature 4 19 6.3E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 PRINTS PR00050 Cold shock protein signature 40 58 6.3E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 Gene3D G3DSA:2.40.50.140 1 67 2.9E-29 T 28-03-2018 SMD44_RS24560 d137743ec8d4de88451cdf131c7d01bb 67 SMART SM00357 3 67 2.3E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 SMD44_RS34355 18812ccac88e8bfc0f6e54c1ffaeea61 92 Pfam PF05120 Gas vesicle protein G 7 72 5.4E-25 T 28-03-2018 IPR007804 Gas vesicle protein GvpG SMD44_RS18530 7ffecfbff89837b8c2a724cc06a7e058 58 Gene3D G3DSA:1.10.1220.10 3 40 7.3E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS18530 7ffecfbff89837b8c2a724cc06a7e058 58 SUPERFAMILY SSF47598 6 38 5.56E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMD44_RS04955 aebd78951bb668992b7f775850e24236 230 Gene3D G3DSA:1.20.144.10 7 226 1.1E-25 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS04955 aebd78951bb668992b7f775850e24236 230 Pfam PF01569 PAP2 superfamily 95 216 5.3E-18 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS04955 aebd78951bb668992b7f775850e24236 230 SMART SM00014 97 211 7.2E-11 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS04955 aebd78951bb668992b7f775850e24236 230 SUPERFAMILY SSF48317 14 219 8.11E-32 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS36735 0a07beb7caa9222c547cd49b9dd23b84 199 SUPERFAMILY SSF56214 76 191 1.13E-12 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS36735 0a07beb7caa9222c547cd49b9dd23b84 199 Gene3D G3DSA:3.90.470.20 84 182 4.3E-7 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS36735 0a07beb7caa9222c547cd49b9dd23b84 199 Gene3D G3DSA:3.90.470.20 1 83 3.6E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS36735 0a07beb7caa9222c547cd49b9dd23b84 199 PRINTS PR01399 Enterobactin synthetase component D signature 44 62 1.5E-19 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD44_RS36735 0a07beb7caa9222c547cd49b9dd23b84 199 PRINTS PR01399 Enterobactin synthetase component D signature 121 137 1.5E-19 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD44_RS36735 0a07beb7caa9222c547cd49b9dd23b84 199 PRINTS PR01399 Enterobactin synthetase component D signature 14 34 1.5E-19 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD44_RS36735 0a07beb7caa9222c547cd49b9dd23b84 199 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 78 156 1.7E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD44_RS10310 31a4aacc923918fcf45349d48699001c 159 Pfam PF08592 Domain of unknown function (DUF1772) 22 155 3.2E-18 T 28-03-2018 IPR013901 Anthrone oxygenase SMD44_RS19795 7872ba9f836c3d4ee09e6c868fb98a89 328 Gene3D G3DSA:3.10.129.10 16 160 0.0032 T 28-03-2018 SMD44_RS19795 7872ba9f836c3d4ee09e6c868fb98a89 328 Pfam PF03756 A-factor biosynthesis hotdog domain 199 325 1.0E-9 T 28-03-2018 IPR005509 A-factor biosynthesis hotdog domain SMD44_RS19795 7872ba9f836c3d4ee09e6c868fb98a89 328 Pfam PF03756 A-factor biosynthesis hotdog domain 23 162 3.2E-29 T 28-03-2018 IPR005509 A-factor biosynthesis hotdog domain SMD44_RS07740 28454a3997073fb73ab39b46f9b01dc6 322 Pfam PF00248 Aldo/keto reductase family 47 305 2.2E-22 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS07740 28454a3997073fb73ab39b46f9b01dc6 322 Gene3D G3DSA:3.20.20.100 1 319 1.4E-36 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS07740 28454a3997073fb73ab39b46f9b01dc6 322 SUPERFAMILY SSF51430 46 307 8.64E-34 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS23275 73d34127f64e0f8588a5fb3370830076 286 Pfam PF00482 Type II secretion system (T2SS), protein F 149 271 1.2E-13 T 28-03-2018 IPR018076 Type II secretion system F domain SMD44_RS43020 706ae4c255762bc8e23c1c22be1a2973 489 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 5 262 7.2E-27 T 28-03-2018 IPR013381 CRISPR-associated protein Cse1 SMD44_RS43020 706ae4c255762bc8e23c1c22be1a2973 489 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 5 447 3.3E-52 T 28-03-2018 IPR013381 CRISPR-associated protein Cse1 SMD44_RS21585 d26810ff09d111bafeb009f7016f30c5 344 SUPERFAMILY SSF51735 303 336 8.13E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21585 d26810ff09d111bafeb009f7016f30c5 344 SUPERFAMILY SSF51735 3 262 8.13E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS21585 d26810ff09d111bafeb009f7016f30c5 344 Gene3D G3DSA:3.40.50.720 4 339 9.0E-39 T 28-03-2018 SMD44_RS21585 d26810ff09d111bafeb009f7016f30c5 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 177 2.0E-14 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS29415 11e3a8e95c5dfa2cac0b666ca4da0fab 750 SUPERFAMILY SSF52540 521 740 8.99E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29415 11e3a8e95c5dfa2cac0b666ca4da0fab 750 SUPERFAMILY SSF52540 173 252 8.99E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS29415 11e3a8e95c5dfa2cac0b666ca4da0fab 750 Gene3D G3DSA:3.30.360.10 40 180 0.0092 T 28-03-2018 SMD44_RS29415 11e3a8e95c5dfa2cac0b666ca4da0fab 750 Gene3D G3DSA:3.40.50.300 598 750 2.3E-9 T 28-03-2018 SMD44_RS29415 11e3a8e95c5dfa2cac0b666ca4da0fab 750 Gene3D G3DSA:3.40.50.300 181 587 1.5E-30 T 28-03-2018 SMD44_RS29415 11e3a8e95c5dfa2cac0b666ca4da0fab 750 Pfam PF13245 AAA domain 185 574 2.9E-11 T 28-03-2018 SMD44_RS03810 768bce0608922ad44b2e1681341b7950 451 SUPERFAMILY SSF53720 21 443 1.19E-122 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS03810 768bce0608922ad44b2e1681341b7950 451 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 253 264 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS03810 768bce0608922ad44b2e1681341b7950 451 Pfam PF00171 Aldehyde dehydrogenase family 14 442 7.1E-88 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS03810 768bce0608922ad44b2e1681341b7950 451 Gene3D G3DSA:3.40.605.10 2 244 4.4E-78 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS03810 768bce0608922ad44b2e1681341b7950 451 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 225 232 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS03810 768bce0608922ad44b2e1681341b7950 451 Gene3D G3DSA:3.40.309.10 245 424 8.3E-64 T 28-03-2018 SMD44_RS03810 768bce0608922ad44b2e1681341b7950 451 PIRSF PIRSF036492 6 451 3.6E-174 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 SMD44_RS27165 f28b4658d608d86d95468c580132febe 325 Pfam PF05990 Alpha/beta hydrolase of unknown function (DUF900) 38 239 1.5E-5 T 28-03-2018 IPR010297 Protein of unknown function DUF900, hydrolase-like SMD44_RS27165 f28b4658d608d86d95468c580132febe 325 Gene3D G3DSA:3.40.50.1820 29 293 1.4E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27165 f28b4658d608d86d95468c580132febe 325 SUPERFAMILY SSF53474 41 84 9.25E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS27165 f28b4658d608d86d95468c580132febe 325 SUPERFAMILY SSF53474 124 246 9.25E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS21910 626240161ad6d46bfc41e9065aa7741f 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 119 4.3E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS21910 626240161ad6d46bfc41e9065aa7741f 128 Gene3D G3DSA:3.10.180.10 7 128 2.9E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS21910 626240161ad6d46bfc41e9065aa7741f 128 SUPERFAMILY SSF54593 8 126 1.06E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS41305 97d0ef2b0b5a8ea1c4d7f5b28648775f 386 Gene3D G3DSA:3.30.470.20 173 380 3.6E-10 T 28-03-2018 SMD44_RS41305 97d0ef2b0b5a8ea1c4d7f5b28648775f 386 SUPERFAMILY SSF56059 114 306 4.2E-19 T 28-03-2018 SMD44_RS41305 97d0ef2b0b5a8ea1c4d7f5b28648775f 386 Gene3D G3DSA:3.30.1490.20 113 172 7.1E-8 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD44_RS33410 d3e1b8a6d9e20f59b83f0fd527f66d61 262 Gene3D G3DSA:3.40.630.30 110 258 6.6E-20 T 28-03-2018 SMD44_RS33410 d3e1b8a6d9e20f59b83f0fd527f66d61 262 Pfam PF13480 Acetyltransferase (GNAT) domain 114 223 1.9E-5 T 28-03-2018 SMD44_RS33410 d3e1b8a6d9e20f59b83f0fd527f66d61 262 SUPERFAMILY SSF55729 60 251 7.03E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS41215 b2f97b84bf50afc3ed4a4245731ad73f 159 Pfam PF03061 Thioesterase superfamily 72 144 1.9E-8 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMD44_RS41215 b2f97b84bf50afc3ed4a4245731ad73f 159 SUPERFAMILY SSF54637 35 151 1.79E-19 T 28-03-2018 IPR029069 HotDog domain SMD44_RS41215 b2f97b84bf50afc3ed4a4245731ad73f 159 Gene3D G3DSA:3.10.129.10 15 157 3.2E-19 T 28-03-2018 SMD44_RS33810 96950b5fdd2cf5050e644ae487732177 373 Pfam PF07730 Histidine kinase 176 238 2.3E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS33810 96950b5fdd2cf5050e644ae487732177 373 Gene3D G3DSA:3.30.565.10 240 373 9.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS33810 96950b5fdd2cf5050e644ae487732177 373 SUPERFAMILY SSF55874 254 370 1.69E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS04905 64c5a0e6e3ebef72816860e16f34d2cc 381 SUPERFAMILY SSF51679 3 375 1.96E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS04905 64c5a0e6e3ebef72816860e16f34d2cc 381 Pfam PF00296 Luciferase-like monooxygenase 23 342 9.2E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS04905 64c5a0e6e3ebef72816860e16f34d2cc 381 Gene3D G3DSA:3.20.20.30 5 380 1.2E-70 T 28-03-2018 SMD44_RS33555 a24114a285fdf5a2bc5010a963eda3d0 202 SUPERFAMILY SSF53597 3 193 1.13E-27 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS33555 a24114a285fdf5a2bc5010a963eda3d0 202 Gene3D G3DSA:3.40.430.10 1 191 4.2E-34 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS33555 a24114a285fdf5a2bc5010a963eda3d0 202 Pfam PF01872 RibD C-terminal domain 2 187 3.9E-26 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS23410 3ec7378c3b891f8cae29f899a5f18b48 399 Gene3D G3DSA:2.80.10.50 2 86 2.7E-7 T 28-03-2018 SMD44_RS23410 3ec7378c3b891f8cae29f899a5f18b48 399 Gene3D G3DSA:4.10.1090.10 87 117 0.097 T 28-03-2018 SMD44_RS23410 3ec7378c3b891f8cae29f899a5f18b48 399 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 46 137 1.7E-11 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS23410 3ec7378c3b891f8cae29f899a5f18b48 399 Gene3D G3DSA:2.80.10.50 118 217 9.9E-6 T 28-03-2018 SMD44_RS23410 3ec7378c3b891f8cae29f899a5f18b48 399 SUPERFAMILY SSF50370 2 154 3.51E-19 T 28-03-2018 IPR000772 Ricin B, lectin domain SMD44_RS28625 439a7952d70934f68dae75faf1cc2e82 232 Gene3D G3DSA:3.40.630.30 60 232 3.3E-14 T 28-03-2018 SMD44_RS28625 439a7952d70934f68dae75faf1cc2e82 232 Pfam PF00583 Acetyltransferase (GNAT) family 149 215 1.7E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS28625 439a7952d70934f68dae75faf1cc2e82 232 SUPERFAMILY SSF55729 125 223 6.0E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS03220 9cb9666a6dd8c01d93163c64637ee9b4 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 280 1.1E-39 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS03220 9cb9666a6dd8c01d93163c64637ee9b4 292 Gene3D G3DSA:1.10.3470.10 9 287 1.1E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS07415 af45775bffd7bb0f19be1e9c3e9875f1 410 Pfam PF03993 Domain of Unknown Function (DUF349) 246 319 1.3E-21 T 28-03-2018 IPR007139 Protein of unknown function DUF349 SMD44_RS07415 af45775bffd7bb0f19be1e9c3e9875f1 410 Pfam PF03993 Domain of Unknown Function (DUF349) 169 242 1.1E-21 T 28-03-2018 IPR007139 Protein of unknown function DUF349 SMD44_RS07415 af45775bffd7bb0f19be1e9c3e9875f1 410 Pfam PF03993 Domain of Unknown Function (DUF349) 93 165 1.0E-12 T 28-03-2018 IPR007139 Protein of unknown function DUF349 SMD44_RS09190 be25214b52ee418b99012310ff74ec55 342 SUPERFAMILY SSF81345 13 334 1.15E-72 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS09190 be25214b52ee418b99012310ff74ec55 342 Pfam PF01032 FecCD transport family 30 334 2.3E-84 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS09190 be25214b52ee418b99012310ff74ec55 342 Gene3D G3DSA:1.10.3470.10 13 342 3.0E-68 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS12285 cb5c3f2c0f4fb803ca49415858a304a5 486 Pfam PF07690 Major Facilitator Superfamily 29 422 1.1E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS12285 cb5c3f2c0f4fb803ca49415858a304a5 486 Gene3D G3DSA:1.20.1250.20 263 483 1.5E-26 T 28-03-2018 SMD44_RS12285 cb5c3f2c0f4fb803ca49415858a304a5 486 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 434 2.2E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD44_RS12285 cb5c3f2c0f4fb803ca49415858a304a5 486 Gene3D G3DSA:1.20.1250.20 20 211 1.8E-30 T 28-03-2018 SMD44_RS12285 cb5c3f2c0f4fb803ca49415858a304a5 486 SUPERFAMILY SSF103473 259 475 6.02E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS12285 cb5c3f2c0f4fb803ca49415858a304a5 486 SUPERFAMILY SSF103473 12 208 6.02E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 Pfam PF00232 Glycosyl hydrolase family 1 9 446 1.7E-152 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 1.2E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 383 1.2E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 PRINTS PR00131 Glycosyl hydrolase family 1 signature 351 359 1.2E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 429 1.2E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 410 1.2E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 Gene3D G3DSA:3.20.20.80 2 450 1.7E-162 T 28-03-2018 SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 TIGRFAM TIGR03356 BGL: beta-galactosidase 11 439 7.2E-188 T 28-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 14 28 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SMD44_RS02750 b7effea0f842c60f48f4f2fc16c5b21c 454 SUPERFAMILY SSF51445 9 447 5.2E-157 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS31940 1a3acff96c7c1f29b85edff801e9ea8c 443 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 363 437 5.4E-10 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SMD44_RS31940 1a3acff96c7c1f29b85edff801e9ea8c 443 SUPERFAMILY SSF50249 9 56 1.03E-9 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS31940 1a3acff96c7c1f29b85edff801e9ea8c 443 Gene3D G3DSA:3.40.50.150 84 437 2.5E-43 T 28-03-2018 SMD44_RS31940 1a3acff96c7c1f29b85edff801e9ea8c 443 Pfam PF01938 TRAM domain 8 67 1.6E-13 T 28-03-2018 IPR002792 TRAM domain SMD44_RS31940 1a3acff96c7c1f29b85edff801e9ea8c 443 SUPERFAMILY SSF53335 75 438 1.27E-56 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS31940 1a3acff96c7c1f29b85edff801e9ea8c 443 Gene3D G3DSA:2.40.50.140 1 83 7.6E-21 T 28-03-2018 SMD44_RS31940 1a3acff96c7c1f29b85edff801e9ea8c 443 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 421 431 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site SMD44_RS25445 56cc28f73211ff0f30019ce0c95feb80 175 SUPERFAMILY SSF160369 1 167 3.01E-50 T 28-03-2018 SMD44_RS25445 56cc28f73211ff0f30019ce0c95feb80 175 Pfam PF00466 Ribosomal protein L10 3 97 3.2E-27 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 SMD44_RS25445 56cc28f73211ff0f30019ce0c95feb80 175 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 157 23.986 T 28-03-2018 IPR022973 Ribosomal protein L10 SMD44_RS25230 af13ae38894a879dc68bcf13d27f63d1 129 Gene3D G3DSA:1.10.10.10 21 127 1.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS25230 af13ae38894a879dc68bcf13d27f63d1 129 Pfam PF01638 HxlR-like helix-turn-helix 24 114 4.8E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS25230 af13ae38894a879dc68bcf13d27f63d1 129 SUPERFAMILY SSF46785 12 125 1.17E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS27275 a8141bcfc41042fcf74e18e5ccffd9e3 217 SMART SM00953 38 188 1.3E-18 T 28-03-2018 IPR014914 RES domain SMD44_RS27275 a8141bcfc41042fcf74e18e5ccffd9e3 217 Pfam PF08808 RES domain 24 190 6.9E-23 T 28-03-2018 IPR014914 RES domain SMD44_RS29560 517655ed3cae3649cc0c8040acaade92 402 SUPERFAMILY SSF141523 232 357 6.8E-21 T 28-03-2018 SMD44_RS29560 517655ed3cae3649cc0c8040acaade92 402 Pfam PF03734 L,D-transpeptidase catalytic domain 229 347 2.4E-10 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD44_RS29560 517655ed3cae3649cc0c8040acaade92 402 Gene3D G3DSA:2.40.440.10 222 359 4.9E-24 T 28-03-2018 SMD44_RS02980 d528dca859dedf524f3304f87e5905f6 315 Gene3D G3DSA:3.40.50.720 1 177 2.6E-33 T 28-03-2018 SMD44_RS02980 d528dca859dedf524f3304f87e5905f6 315 SUPERFAMILY SSF51735 2 184 2.63E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02980 d528dca859dedf524f3304f87e5905f6 315 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 300 7.0E-75 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS02980 d528dca859dedf524f3304f87e5905f6 315 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 299 1.4E-26 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS02980 d528dca859dedf524f3304f87e5905f6 315 Gene3D G3DSA:1.10.1040.10 178 309 1.2E-28 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS02980 d528dca859dedf524f3304f87e5905f6 315 SUPERFAMILY SSF48179 178 298 6.12E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD44_RS02980 d528dca859dedf524f3304f87e5905f6 315 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 152 1.2E-38 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMD44_RS05095 9301f80947a77edc093e01e25c7a1255 346 SUPERFAMILY SSF53474 61 345 2.16E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS05095 9301f80947a77edc093e01e25c7a1255 346 Pfam PF00561 alpha/beta hydrolase fold 85 174 4.2E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS05095 9301f80947a77edc093e01e25c7a1255 346 PRINTS PR00412 Epoxide hydrolase signature 155 168 8.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS05095 9301f80947a77edc093e01e25c7a1255 346 PRINTS PR00412 Epoxide hydrolase signature 91 109 8.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS05095 9301f80947a77edc093e01e25c7a1255 346 PRINTS PR00412 Epoxide hydrolase signature 321 343 8.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMD44_RS05095 9301f80947a77edc093e01e25c7a1255 346 Gene3D G3DSA:3.40.50.1820 52 346 3.2E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS31720 09e217f3f6c470ea9ec039a0aeec89c2 98 Pfam PF13834 Domain of unknown function (DUF4193) 1 97 2.6E-45 T 28-03-2018 IPR025242 Protein of unknown function DUF4193 SMD44_RS29970 eff7ab116bc44bb6e34967a7acbbd00a 243 SUPERFAMILY SSF55469 45 241 3.53E-41 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS29970 eff7ab116bc44bb6e34967a7acbbd00a 243 Pfam PF00881 Nitroreductase family 52 221 2.9E-21 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD44_RS29970 eff7ab116bc44bb6e34967a7acbbd00a 243 Gene3D G3DSA:3.40.109.10 27 243 3.9E-38 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS26205 4100bed9dc4d3c78be7e5e9d8c4bef89 157 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 138 6.7E-24 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type SMD44_RS26205 4100bed9dc4d3c78be7e5e9d8c4bef89 157 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site SMD44_RS26205 4100bed9dc4d3c78be7e5e9d8c4bef89 157 Pfam PF02082 Transcriptional regulator 1 83 8.5E-20 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type SMD44_RS26205 4100bed9dc4d3c78be7e5e9d8c4bef89 157 SUPERFAMILY SSF46785 3 141 3.13E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS26205 4100bed9dc4d3c78be7e5e9d8c4bef89 157 Gene3D G3DSA:1.10.10.10 1 152 6.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29795 b5c1088a278b6f72f5c1dfd506a347df 182 Pfam PF03641 Possible lysine decarboxylase 47 174 2.3E-30 T 28-03-2018 IPR031100 LOG family SMD44_RS29795 b5c1088a278b6f72f5c1dfd506a347df 182 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 168 2.1E-32 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG SMD44_RS29795 b5c1088a278b6f72f5c1dfd506a347df 182 SUPERFAMILY SSF102405 4 177 1.68E-41 T 28-03-2018 SMD44_RS29795 b5c1088a278b6f72f5c1dfd506a347df 182 Gene3D G3DSA:3.40.50.450 2 181 5.4E-36 T 28-03-2018 SMD44_RS04555 2b3c14db72eb874b9b4723e63821bef2 101 Gene3D G3DSA:3.20.20.30 2 100 4.6E-4 T 28-03-2018 SMD44_RS04780 bb29685f24d35383880399c5445fa8c7 419 Gene3D G3DSA:3.40.190.10 31 212 1.3E-28 T 28-03-2018 SMD44_RS04780 bb29685f24d35383880399c5445fa8c7 419 Pfam PF01547 Bacterial extracellular solute-binding protein 50 332 7.8E-33 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS04780 bb29685f24d35383880399c5445fa8c7 419 SUPERFAMILY SSF53850 24 416 1.73E-58 T 28-03-2018 SMD44_RS04780 bb29685f24d35383880399c5445fa8c7 419 Gene3D G3DSA:3.40.190.10 213 374 1.3E-6 T 28-03-2018 SMD44_RS40545 cbfd9189ab973b080e0f82615cf3ed12 163 Pfam PF13581 Histidine kinase-like ATPase domain 54 158 2.2E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS40545 cbfd9189ab973b080e0f82615cf3ed12 163 Gene3D G3DSA:3.30.565.10 36 163 2.3E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS40545 cbfd9189ab973b080e0f82615cf3ed12 163 SUPERFAMILY SSF55874 70 159 1.26E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS43205 e9aee61ebd4001a67115b6d3334ac0bd 261 Gene3D G3DSA:3.20.20.105 23 220 4.4E-7 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SMD44_RS33560 d1459d267562290e23fef1b1314a442e 157 Gene3D G3DSA:3.10.450.30 62 157 2.7E-35 T 28-03-2018 SMD44_RS33560 d1459d267562290e23fef1b1314a442e 157 SUPERFAMILY SSF53933 63 154 4.37E-38 T 28-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD44_RS33560 d1459d267562290e23fef1b1314a442e 157 Pfam PF00545 ribonuclease 72 151 9.0E-30 T 28-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 SMD44_RS17260 1585bf82dd9ebfd31d9575b7d9e0ef1f 258 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 7 229 22.916 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 SMD44_RS17260 1585bf82dd9ebfd31d9575b7d9e0ef1f 258 Pfam PF02525 Flavodoxin-like fold 9 196 4.4E-24 T 28-03-2018 IPR003680 Flavodoxin-like fold SMD44_RS17260 1585bf82dd9ebfd31d9575b7d9e0ef1f 258 Gene3D G3DSA:3.40.50.360 9 231 1.1E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS17260 1585bf82dd9ebfd31d9575b7d9e0ef1f 258 SUPERFAMILY SSF52218 10 227 1.01E-28 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS26910 684f07446db3f0aff0a3fc65830b090c 363 Pfam PF10756 Bacterial PH domain 219 283 5.8E-10 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 SMD44_RS41565 a49262f54fbc11a1e2aca670f48b1b8a 138 Pfam PF05423 Mycobacterium membrane protein 28 128 7.8E-6 T 28-03-2018 IPR008693 Transport accessory protein MmpS SMD44_RS28150 bc9a42bed3b5a68656fc97e7da952a5b 251 Pfam PF01987 Mitochondrial biogenesis AIM24 21 215 5.5E-30 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS28150 bc9a42bed3b5a68656fc97e7da952a5b 251 SUPERFAMILY SSF51219 17 223 1.23E-41 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD44_RS28150 bc9a42bed3b5a68656fc97e7da952a5b 251 Gene3D G3DSA:3.60.160.10 6 237 6.4E-42 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS38820 5561a302d06ee84cfa31d604ff28c8e5 425 SUPERFAMILY SSF53756 1 391 2.59E-65 T 28-03-2018 SMD44_RS38820 5561a302d06ee84cfa31d604ff28c8e5 425 Gene3D G3DSA:3.40.50.2000 1 213 5.7E-11 T 28-03-2018 SMD44_RS38820 5561a302d06ee84cfa31d604ff28c8e5 425 Pfam PF00534 Glycosyl transferases group 1 217 370 3.3E-27 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 SMD44_RS38820 5561a302d06ee84cfa31d604ff28c8e5 425 Pfam PF13439 Glycosyltransferase Family 4 17 204 6.1E-18 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMD44_RS38820 5561a302d06ee84cfa31d604ff28c8e5 425 Gene3D G3DSA:3.40.50.2000 214 376 1.0E-35 T 28-03-2018 SMD44_RS08495 d4b7269dce9e07afdea7d3389e52c490 120 Pfam PF02656 Domain of unknown function (DUF202) 24 86 1.3E-10 T 28-03-2018 IPR003807 Domain of unknown function DUF202 SMD44_RS12000 1631e14289726c7b4d4d204be5673117 237 Gene3D G3DSA:3.40.50.720 20 226 2.5E-27 T 28-03-2018 SMD44_RS12000 1631e14289726c7b4d4d204be5673117 237 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 24 234 3.6E-78 T 28-03-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 SMD44_RS12000 1631e14289726c7b4d4d204be5673117 237 SUPERFAMILY SSF51735 26 231 1.56E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS12000 1631e14289726c7b4d4d204be5673117 237 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 26 120 2.9E-21 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMD44_RS40540 1b35ed0451f70c042250a0c70598353d 116 Gene3D G3DSA:3.30.750.24 10 116 1.2E-9 T 28-03-2018 IPR002645 STAS domain SMD44_RS40540 1b35ed0451f70c042250a0c70598353d 116 SUPERFAMILY SSF52091 18 114 3.53E-12 T 28-03-2018 IPR002645 STAS domain SMD44_RS43260 b033d872fd0b71539238bc9ff3b734e8 212 Gene3D G3DSA:3.40.50.150 68 174 2.5E-9 T 28-03-2018 SMD44_RS43260 b033d872fd0b71539238bc9ff3b734e8 212 SUPERFAMILY SSF53335 42 165 1.52E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS43260 b033d872fd0b71539238bc9ff3b734e8 212 Pfam PF02384 N-6 DNA Methylase 64 168 1.1E-9 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMD44_RS25820 53b996de92c43956622035de86e888ca 374 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 367 8.3E-197 T 28-03-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 SMD44_RS25820 53b996de92c43956622035de86e888ca 374 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 15 297 5.8E-43 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMD44_RS25820 53b996de92c43956622035de86e888ca 374 Gene3D G3DSA:3.20.20.70 15 368 2.4E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS25820 53b996de92c43956622035de86e888ca 374 SUPERFAMILY SSF51412 12 77 9.46E-69 T 28-03-2018 SMD44_RS25820 53b996de92c43956622035de86e888ca 374 SUPERFAMILY SSF51412 113 369 9.46E-69 T 28-03-2018 SMD44_RS25820 53b996de92c43956622035de86e888ca 374 SMART SM01240 14 373 2.9E-27 T 28-03-2018 SMD44_RS16925 2c9c854454d6cc3787032cf109f0753c 447 Pfam PF07730 Histidine kinase 207 271 3.0E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS16925 2c9c854454d6cc3787032cf109f0753c 447 SUPERFAMILY SSF55874 331 442 3.01E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS16925 2c9c854454d6cc3787032cf109f0753c 447 Gene3D G3DSA:3.30.565.10 318 445 5.3E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 SUPERFAMILY SSF117892 52 186 2.62E-39 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 SMART SM00244 21 179 2.2E-52 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 PRINTS PR00721 Stomatin signature 111 128 1.7E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 PRINTS PR00721 Stomatin signature 131 154 1.7E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 PRINTS PR00721 Stomatin signature 28 50 1.7E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 PRINTS PR00721 Stomatin signature 174 195 1.7E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 PRINTS PR00721 Stomatin signature 155 173 1.7E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 PRINTS PR00721 Stomatin signature 76 97 1.7E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 Pfam PF01145 SPFH domain / Band 7 family 25 194 5.3E-34 T 28-03-2018 IPR001107 Band 7 domain SMD44_RS09275 d4ce3d082d2b7a5a90ee10b9f78cc7bc 318 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site SMD44_RS21015 2749f4dc8275ef99c138f22e0794a3b3 226 SUPERFAMILY SSF46785 8 182 4.2E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21015 2749f4dc8275ef99c138f22e0794a3b3 226 Pfam PF03551 Transcriptional regulator PadR-like family 12 92 2.4E-15 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS21015 2749f4dc8275ef99c138f22e0794a3b3 226 Gene3D G3DSA:1.20.120.330 101 203 8.7E-4 T 28-03-2018 SMD44_RS21015 2749f4dc8275ef99c138f22e0794a3b3 226 Gene3D G3DSA:1.10.10.10 1 100 9.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17915 3e2c3dfc68dd79a34ab163188d21b8b0 383 PIRSF PIRSF000429 2 372 2.8E-18 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMD44_RS17915 3e2c3dfc68dd79a34ab163188d21b8b0 383 SUPERFAMILY SSF53901 9 228 1.78E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS17915 3e2c3dfc68dd79a34ab163188d21b8b0 383 Gene3D G3DSA:3.40.47.10 147 375 2.1E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS17915 3e2c3dfc68dd79a34ab163188d21b8b0 383 Gene3D G3DSA:3.40.47.10 18 146 5.9E-4 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS17915 3e2c3dfc68dd79a34ab163188d21b8b0 383 SUPERFAMILY SSF53901 251 368 1.31E-12 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS31440 7bafc69c90a19a7ac9ea35fa9c5f058d 176 Pfam PF02342 TerD domain 5 169 1.3E-22 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS31440 7bafc69c90a19a7ac9ea35fa9c5f058d 176 Gene3D G3DSA:2.60.60.30 6 171 8.3E-38 T 28-03-2018 SMD44_RS06000 e0def35e6517690ae25b66e19e9dac52 341 Gene3D G3DSA:3.90.226.10 1 324 1.2E-89 T 28-03-2018 SMD44_RS06000 e0def35e6517690ae25b66e19e9dac52 341 SUPERFAMILY SSF52096 243 313 1.99E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS06000 e0def35e6517690ae25b66e19e9dac52 341 SUPERFAMILY SSF52096 1 191 1.99E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS06000 e0def35e6517690ae25b66e19e9dac52 341 Pfam PF16113 Enoyl-CoA hydratase/isomerase 10 330 5.2E-122 T 28-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 SMD44_RS14795 f47e92ad56de9af41d7e250aa5087a75 182 Pfam PF06078 Bacterial protein of unknown function (DUF937) 12 137 6.3E-7 T 28-03-2018 IPR009282 Protein of unknown function DUF937 SMD44_RS19990 684bbe754ff15bfa8b73f05b7500b9d5 105 Pfam PF11774 Lsr2 2 104 1.0E-35 T 28-03-2018 IPR024412 Lsr2 SMD44_RS19990 684bbe754ff15bfa8b73f05b7500b9d5 105 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 105 3.0E-45 T 28-03-2018 IPR024412 Lsr2 SMD44_RS31315 ea684eb4b3f92a383ff9092294ba9d3c 171 Pfam PF03780 Asp23 family, cell envelope-related function 46 156 5.5E-31 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 SMD44_RS28335 5ddb027a19a5d0e002b0a3cd19b89672 93 Pfam PF11755 Protein of unknown function (DUF3311) 28 85 4.8E-24 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 SMD44_RS00660 0932bf9f4748f18ba3264e274f24bef0 370 Gene3D G3DSA:3.20.20.140 20 311 1.1E-52 T 28-03-2018 SMD44_RS00660 0932bf9f4748f18ba3264e274f24bef0 370 SUPERFAMILY SSF51338 293 367 9.93E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS00660 0932bf9f4748f18ba3264e274f24bef0 370 SUPERFAMILY SSF51556 8 294 1.28E-64 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS00660 0932bf9f4748f18ba3264e274f24bef0 370 Gene3D G3DSA:2.30.40.10 1 19 2.4E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS00660 0932bf9f4748f18ba3264e274f24bef0 370 Pfam PF01979 Amidohydrolase family 5 341 4.0E-47 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMD44_RS15050 03f0cfa494a1458635a6e0d9b55b128b 446 Pfam PF13416 Bacterial extracellular solute-binding protein 70 378 1.1E-28 T 28-03-2018 SMD44_RS15050 03f0cfa494a1458635a6e0d9b55b128b 446 SUPERFAMILY SSF53850 50 444 1.48E-51 T 28-03-2018 SMD44_RS15050 03f0cfa494a1458635a6e0d9b55b128b 446 Gene3D G3DSA:3.40.190.10 37 207 1.2E-26 T 28-03-2018 SMD44_RS15050 03f0cfa494a1458635a6e0d9b55b128b 446 Gene3D G3DSA:3.40.190.10 208 401 5.9E-16 T 28-03-2018 SMD44_RS14245 32a69a408e04c439b65d37b06616992a 469 Pfam PF00324 Amino acid permease 25 433 4.0E-100 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD44_RS14245 32a69a408e04c439b65d37b06616992a 469 ProSitePatterns PS00218 Amino acid permeases signature. 50 80 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD44_RS14245 32a69a408e04c439b65d37b06616992a 469 PIRSF PIRSF006060 7 466 6.3E-64 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS00555 7c9e43e2ff0279bd6abb3c515ca03da1 1050 SUPERFAMILY SSF52540 52 241 1.32E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00555 7c9e43e2ff0279bd6abb3c515ca03da1 1050 Gene3D G3DSA:3.40.50.300 45 193 2.2E-10 T 28-03-2018 SMD44_RS21925 ddc872f46f31043c5504c5a47c1b2629 754 Gene3D G3DSA:3.40.50.300 32 312 7.1E-5 T 28-03-2018 SMD44_RS41955 c074f3c20288071e5f1c0d546ba38c0d 367 SUPERFAMILY SSF55874 234 351 1.81E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41955 c074f3c20288071e5f1c0d546ba38c0d 367 Gene3D G3DSA:3.30.565.10 225 359 9.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41955 c074f3c20288071e5f1c0d546ba38c0d 367 Pfam PF07730 Histidine kinase 157 218 2.6E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 SUPERFAMILY SSF81442 2 510 4.06E-173 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 232 286 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 Gene3D G3DSA:1.20.210.10 1 511 1.1E-194 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 3 507 1.1E-211 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 333 351 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 276 291 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 76 100 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 230 251 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 2 27 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 119 131 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 380 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 209 230 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 298 319 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 151 169 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 180 199 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 432 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 49 72 1.3E-103 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS22190 25a93e7c4e532a436cf35dfc8e123fa3 541 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 12 454 1.7E-143 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS33015 e2b43af88b9051f27ef55d5c45614f2b 258 Gene3D G3DSA:1.25.40.10 23 237 3.0E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS29635 3becbd2506640f5eb78bfd5c8fd3d5b4 148 Gene3D G3DSA:3.40.1800.10 44 112 4.4E-5 T 28-03-2018 SMD44_RS29635 3becbd2506640f5eb78bfd5c8fd3d5b4 148 SUPERFAMILY SSF54060 45 135 2.71E-14 T 28-03-2018 SMD44_RS29635 3becbd2506640f5eb78bfd5c8fd3d5b4 148 Pfam PF02945 Recombination endonuclease VII 44 110 8.7E-14 T 28-03-2018 IPR004211 Recombination endonuclease VII SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 171 195 3.5E-11 T 28-03-2018 SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 207 230 3.5E-11 T 28-03-2018 SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 238 262 3.5E-11 T 28-03-2018 SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 124 145 3.5E-11 T 28-03-2018 SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 SUPERFAMILY SSF53383 12 405 2.86E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 Gene3D G3DSA:3.40.640.10 61 283 6.6E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 Gene3D G3DSA:3.40.50.2300 3 60 0.16 T 28-03-2018 SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 Pfam PF00155 Aminotransferase class I and II 40 396 2.4E-74 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS25395 6d9a57a15d42e37ce6b21a774ad39497 408 Gene3D G3DSA:3.90.1150.10 284 408 2.8E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS20935 5971dc822d44227afdd8527b23decc60 152 SUPERFAMILY SSF46785 12 132 2.65E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20935 5971dc822d44227afdd8527b23decc60 152 SMART SM00347 32 137 4.0E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20935 5971dc822d44227afdd8527b23decc60 152 Pfam PF01047 MarR family 59 101 1.8E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20935 5971dc822d44227afdd8527b23decc60 152 Gene3D G3DSA:1.10.10.10 18 150 4.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20935 5971dc822d44227afdd8527b23decc60 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 6.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20935 5971dc822d44227afdd8527b23decc60 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 6.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS20935 5971dc822d44227afdd8527b23decc60 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 6.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS19120 38aa2f61be3fc473e9d3ac92efcd1d76 182 Pfam PF06353 Protein of unknown function (DUF1062) 35 165 5.1E-39 T 28-03-2018 IPR009412 Protein of unknown function DUF1062 SMD44_RS31095 97ff66d7206bd0a2445804a9c756fd0d 224 Gene3D G3DSA:3.40.640.10 1 114 6.2E-14 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS31095 97ff66d7206bd0a2445804a9c756fd0d 224 SUPERFAMILY SSF53383 3 214 3.68E-34 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS31095 97ff66d7206bd0a2445804a9c756fd0d 224 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 106 212 1.8E-11 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD44_RS31095 97ff66d7206bd0a2445804a9c756fd0d 224 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 4 97 2.0E-28 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD44_RS31095 97ff66d7206bd0a2445804a9c756fd0d 224 Gene3D G3DSA:3.90.1150.10 115 216 3.5E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS37660 03909fd77b2386c83f18bb6a6589bf81 415 Pfam PF00999 Sodium/hydrogen exchanger family 10 381 2.6E-44 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD44_RS37830 68b40a938b88dc40f242e365aaac8885 319 Gene3D G3DSA:3.20.20.30 5 318 1.1E-56 T 28-03-2018 SMD44_RS37830 68b40a938b88dc40f242e365aaac8885 319 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 316 4.5E-142 T 28-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related SMD44_RS37830 68b40a938b88dc40f242e365aaac8885 319 SUPERFAMILY SSF51679 2 317 2.49E-63 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS37830 68b40a938b88dc40f242e365aaac8885 319 Pfam PF00296 Luciferase-like monooxygenase 3 291 7.5E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS18425 984ead9d46f4cd9f8f475c613f3d6814 279 SUPERFAMILY SSF51735 2 210 1.09E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS18425 984ead9d46f4cd9f8f475c613f3d6814 279 Pfam PF13460 NAD(P)H-binding 6 137 1.1E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS18425 984ead9d46f4cd9f8f475c613f3d6814 279 Gene3D G3DSA:3.40.50.720 1 278 2.1E-26 T 28-03-2018 SMD44_RS25190 d60df7fb368d035801f0367444815589 149 SUPERFAMILY SSF54593 7 148 1.15E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS25190 d60df7fb368d035801f0367444815589 149 Gene3D G3DSA:3.10.180.10 5 149 6.4E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS02350 ae6bcc6a8cd7dd601b5b45bb5fc77869 322 Gene3D G3DSA:3.20.20.150 64 322 6.6E-55 T 28-03-2018 SMD44_RS02350 ae6bcc6a8cd7dd601b5b45bb5fc77869 322 Pfam PF01261 Xylose isomerase-like TIM barrel 83 281 1.4E-27 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS02350 ae6bcc6a8cd7dd601b5b45bb5fc77869 322 SUPERFAMILY SSF51658 65 317 1.52E-73 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS09690 e0105196318bc1140cbfc384d3272998 366 PIRSF PIRSF000524 14 366 6.6E-64 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 SMD44_RS09690 e0105196318bc1140cbfc384d3272998 366 Gene3D G3DSA:3.40.640.10 6 238 9.5E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS09690 e0105196318bc1140cbfc384d3272998 366 Pfam PF00266 Aminotransferase class-V 17 300 7.3E-24 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS09690 e0105196318bc1140cbfc384d3272998 366 Gene3D G3DSA:3.90.1150.10 239 366 3.0E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS09690 e0105196318bc1140cbfc384d3272998 366 SUPERFAMILY SSF53383 16 348 1.21E-61 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS14545 43157ba40657c844adb1a7c89aa0910d 180 Pfam PF00583 Acetyltransferase (GNAT) family 43 149 4.8E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS14545 43157ba40657c844adb1a7c89aa0910d 180 SUPERFAMILY SSF55729 13 160 4.12E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS14545 43157ba40657c844adb1a7c89aa0910d 180 Gene3D G3DSA:3.40.630.30 7 175 1.3E-22 T 28-03-2018 SMD44_RS00980 6850acf91de22183abb4659582372dad 512 Gene3D G3DSA:4.10.450.10 74 143 0.0014 T 28-03-2018 SMD44_RS00980 6850acf91de22183abb4659582372dad 512 SUPERFAMILY SSF54373 328 456 2.55E-43 T 28-03-2018 SMD44_RS00980 6850acf91de22183abb4659582372dad 512 Gene3D G3DSA:3.30.410.10 170 280 5.2E-17 T 28-03-2018 SMD44_RS00980 6850acf91de22183abb4659582372dad 512 Gene3D G3DSA:3.30.410.10 281 448 2.1E-59 T 28-03-2018 SMD44_RS00980 6850acf91de22183abb4659582372dad 512 SUPERFAMILY SSF51905 453 509 2.9E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00980 6850acf91de22183abb4659582372dad 512 SUPERFAMILY SSF51905 23 324 2.9E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00980 6850acf91de22183abb4659582372dad 512 Gene3D G3DSA:3.50.50.60 3 73 5.5E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS00980 6850acf91de22183abb4659582372dad 512 Pfam PF05199 GMC oxidoreductase 451 502 1.4E-13 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD44_RS06615 7c8ba81d5830848397b959c56d7ae03b 247 Gene3D G3DSA:1.10.1660.10 147 242 0.19 T 28-03-2018 SMD44_RS06615 7c8ba81d5830848397b959c56d7ae03b 247 Gene3D G3DSA:1.10.1660.10 11 146 1.2E-22 T 28-03-2018 SMD44_RS06615 7c8ba81d5830848397b959c56d7ae03b 247 SUPERFAMILY SSF46955 36 103 1.98E-13 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS06615 7c8ba81d5830848397b959c56d7ae03b 247 SMART SM00422 21 95 4.8E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS06615 7c8ba81d5830848397b959c56d7ae03b 247 Pfam PF00376 MerR family regulatory protein 22 63 3.9E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD44_RS03835 664c55fde29333ca6c97452239be4050 302 Pfam PF01758 Sodium Bile acid symporter family 13 195 2.0E-34 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SMD44_RS12625 3481ad45906af74c3c0f67808525858a 268 Pfam PF13349 Putative adhesin 120 241 2.5E-12 T 28-03-2018 IPR025164 Putative adhesin SMD44_RS09155 02a8c6f65f328ca1ee1914cacb258301 572 Gene3D G3DSA:3.40.50.300 1 546 2.0E-36 T 28-03-2018 SMD44_RS09155 02a8c6f65f328ca1ee1914cacb258301 572 SUPERFAMILY SSF52540 2 216 4.65E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09155 02a8c6f65f328ca1ee1914cacb258301 572 Pfam PF02463 RecF/RecN/SMC N terminal domain 12 525 1.5E-17 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SMD44_RS09155 02a8c6f65f328ca1ee1914cacb258301 572 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 5.9E-160 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SMD44_RS09155 02a8c6f65f328ca1ee1914cacb258301 572 SUPERFAMILY SSF52540 394 520 9.35E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09155 02a8c6f65f328ca1ee1914cacb258301 572 SUPERFAMILY SSF52540 4 46 9.35E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS09155 02a8c6f65f328ca1ee1914cacb258301 572 PIRSF PIRSF003128 1 571 2.5E-153 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SMD44_RS43895 837e6ebc596e3132335989fda0bb02e5 245 Pfam PF10979 Protein of unknown function (DUF2786) 10 47 3.0E-11 T 28-03-2018 IPR024498 Domain of unknown function DUF2786 SMD44_RS43895 837e6ebc596e3132335989fda0bb02e5 245 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 43 161 2.0E-15 T 28-03-2018 SMD44_RS42840 327ec14b8bfbd4ce5658ef98814ae7aa 95 SUPERFAMILY SSF55781 2 79 4.49E-10 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS42840 327ec14b8bfbd4ce5658ef98814ae7aa 95 Gene3D G3DSA:3.30.450.40 1 84 2.1E-10 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS42840 327ec14b8bfbd4ce5658ef98814ae7aa 95 Pfam PF01590 GAF domain 6 77 2.3E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS36090 4face0ab9f92549ee20edf63dd7839b6 217 Pfam PF12680 SnoaL-like domain 94 200 7.7E-18 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS36090 4face0ab9f92549ee20edf63dd7839b6 217 SUPERFAMILY SSF54427 89 214 3.2E-29 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS36090 4face0ab9f92549ee20edf63dd7839b6 217 Gene3D G3DSA:3.10.450.50 78 217 5.2E-27 T 28-03-2018 SMD44_RS16850 f2a9b8118e00b52a7cca37d57050acc2 245 Pfam PF07510 Protein of unknown function (DUF1524) 85 220 5.7E-15 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 SMD44_RS30675 d09e17a2177b1efc538acd2c7204c0c5 396 Pfam PF00144 Beta-lactamase 63 379 2.5E-49 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS30675 d09e17a2177b1efc538acd2c7204c0c5 396 Gene3D G3DSA:3.40.710.10 50 395 3.5E-64 T 28-03-2018 SMD44_RS30675 d09e17a2177b1efc538acd2c7204c0c5 396 SUPERFAMILY SSF56601 65 373 6.13E-62 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS19640 309d6f289d0e0b987310b8465e1460a9 399 Pfam PF05426 Alginate lyase 108 332 2.1E-17 T 28-03-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 SMD44_RS19640 309d6f289d0e0b987310b8465e1460a9 399 Gene3D G3DSA:1.50.10.100 29 368 2.6E-67 T 28-03-2018 SMD44_RS19640 309d6f289d0e0b987310b8465e1460a9 399 SUPERFAMILY SSF48230 49 252 1.46E-45 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMD44_RS19640 309d6f289d0e0b987310b8465e1460a9 399 SUPERFAMILY SSF48230 282 372 1.46E-45 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMD44_RS12635 e6617333be9d64cf0147aaceeceb925a 173 Pfam PF14325 Domain of unknown function (DUF4383) 36 150 3.4E-12 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 SMD44_RS32460 9f9043014b9637e4e5c8ca78c686a6af 294 Gene3D G3DSA:3.20.20.370 56 292 7.4E-44 T 28-03-2018 SMD44_RS32460 9f9043014b9637e4e5c8ca78c686a6af 294 Pfam PF01522 Polysaccharide deacetylase 72 213 1.3E-25 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS32460 9f9043014b9637e4e5c8ca78c686a6af 294 SUPERFAMILY SSF88713 72 283 7.41E-45 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS05625 c4878bb6c7393943644dec061aa0b36f 342 SUPERFAMILY SSF51735 1 309 1.91E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS05625 c4878bb6c7393943644dec061aa0b36f 342 Gene3D G3DSA:3.40.50.720 1 72 2.9E-8 T 28-03-2018 SMD44_RS05625 c4878bb6c7393943644dec061aa0b36f 342 Gene3D G3DSA:3.40.50.720 73 167 0.022 T 28-03-2018 SMD44_RS05625 c4878bb6c7393943644dec061aa0b36f 342 Gene3D G3DSA:3.90.25.10 168 323 2.6E-15 T 28-03-2018 SMD44_RS05625 c4878bb6c7393943644dec061aa0b36f 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 72 1.2E-4 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS28425 31c520cf916d32a2318562f2661ec2e9 86 Gene3D G3DSA:3.30.40.10 1 86 1.1E-19 T 28-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type SMD44_RS28425 31c520cf916d32a2318562f2661ec2e9 86 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 34 82 1.4E-11 T 28-03-2018 IPR001607 Zinc finger, UBP-type GO:0008270 SMD44_RS28425 31c520cf916d32a2318562f2661ec2e9 86 SUPERFAMILY SSF57850 3 85 1.41E-25 T 28-03-2018 SMD44_RS37395 f868550ed743b4b332e64ee07f826ae5 307 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 22 178 6.7E-22 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS37395 f868550ed743b4b332e64ee07f826ae5 307 Gene3D G3DSA:3.40.50.720 14 177 1.0E-25 T 28-03-2018 SMD44_RS37395 f868550ed743b4b332e64ee07f826ae5 307 SUPERFAMILY SSF51735 22 178 1.35E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS37395 f868550ed743b4b332e64ee07f826ae5 307 PIRSF PIRSF000103 14 307 4.3E-38 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS37395 f868550ed743b4b332e64ee07f826ae5 307 Gene3D G3DSA:1.10.1040.10 179 307 1.6E-11 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS34460 8be699eb898a51544a33a1c884ebef7a 249 Gene3D G3DSA:3.60.15.10 1 249 2.0E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS34460 8be699eb898a51544a33a1c884ebef7a 249 SUPERFAMILY SSF56281 1 209 8.82E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS34460 8be699eb898a51544a33a1c884ebef7a 249 Pfam PF12706 Beta-lactamase superfamily domain 6 198 3.5E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS05255 70d728fd24d726843eecf453377fc0a4 93 Pfam PF02583 Metal-sensitive transcriptional repressor 11 80 1.6E-25 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SMD44_RS31430 a6b32e720cd671b6e4ff0ac137263f40 180 Pfam PF03477 ATP cone domain 47 132 2.6E-13 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 SMD44_RS31430 a6b32e720cd671b6e4ff0ac137263f40 180 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 6.3E-45 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SMD44_RS31430 a6b32e720cd671b6e4ff0ac137263f40 180 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 77.041 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SMD44_RS30100 cdc0b1d153b0472e1d6652b38feff538 458 Gene3D G3DSA:3.40.50.1220 55 251 0.0069 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS01620 6b7868e087cc912b1e9940be1a4dfbe8 294 SUPERFAMILY SSF51430 1 292 2.49E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS01620 6b7868e087cc912b1e9940be1a4dfbe8 294 Pfam PF00248 Aldo/keto reductase family 14 288 1.6E-58 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS01620 6b7868e087cc912b1e9940be1a4dfbe8 294 Gene3D G3DSA:3.20.20.100 1 294 1.4E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS13360 e05e2bcaae24a793cc1377519f6cc55c 159 Gene3D G3DSA:3.10.490.10 1 139 2.7E-26 T 28-03-2018 SMD44_RS13360 e05e2bcaae24a793cc1377519f6cc55c 159 SUPERFAMILY SSF110857 3 131 3.27E-20 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like SMD44_RS13360 e05e2bcaae24a793cc1377519f6cc55c 159 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 3 131 2.3E-22 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like SMD44_RS28975 b3268014366b685d462b5f52759ec42b 362 Gene3D G3DSA:3.20.20.30 1 362 3.4E-86 T 28-03-2018 SMD44_RS28975 b3268014366b685d462b5f52759ec42b 362 SUPERFAMILY SSF51679 1 361 6.71E-66 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS28975 b3268014366b685d462b5f52759ec42b 362 Pfam PF00296 Luciferase-like monooxygenase 1 331 7.9E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS37430 369b5d2ceea91a11012a53b8ae87ba51 385 Pfam PF01757 Acyltransferase family 2 331 4.0E-32 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMD44_RS22140 a17cd5d2650923d2bdeb922040e8312e 223 SUPERFAMILY SSF48498 104 214 4.19E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS22140 a17cd5d2650923d2bdeb922040e8312e 223 Gene3D G3DSA:1.10.10.60 1 77 2.2E-10 T 28-03-2018 SMD44_RS22140 a17cd5d2650923d2bdeb922040e8312e 223 Gene3D G3DSA:1.10.357.10 78 219 1.4E-20 T 28-03-2018 SMD44_RS22140 a17cd5d2650923d2bdeb922040e8312e 223 SUPERFAMILY SSF46689 21 92 1.94E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS26735 203bb0845731f16564f96889159f7af4 415 Gene3D G3DSA:1.10.260.40 16 94 3.1E-8 T 28-03-2018 SMD44_RS26735 203bb0845731f16564f96889159f7af4 415 Pfam PF13560 Helix-turn-helix domain 25 84 4.2E-9 T 28-03-2018 SMD44_RS26735 203bb0845731f16564f96889159f7af4 415 SMART SM00530 27 83 9.1E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS26735 203bb0845731f16564f96889159f7af4 415 SUPERFAMILY SSF48452 183 363 6.65E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS26735 203bb0845731f16564f96889159f7af4 415 Gene3D G3DSA:1.25.40.10 104 415 3.2E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS26735 203bb0845731f16564f96889159f7af4 415 SUPERFAMILY SSF47413 24 68 2.28E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS12490 d64e3f824f15b2038f6a6a776fbaa3d0 134 Pfam PF09350 Domain of unknown function (DUF1992) 14 77 2.6E-18 T 28-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain SMD44_RS42320 3e8ddc287333931ab8a976bcb2240191 223 Gene3D G3DSA:3.40.630.30 11 160 1.3E-21 T 28-03-2018 SMD44_RS42320 3e8ddc287333931ab8a976bcb2240191 223 Pfam PF00583 Acetyltransferase (GNAT) family 57 151 2.4E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS42320 3e8ddc287333931ab8a976bcb2240191 223 SUPERFAMILY SSF55729 17 170 3.6E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS20620 c3958d2f2c6920f5a9de014baaa66ba7 233 SMART SM00943 30 209 6.7E-28 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS20620 c3958d2f2c6920f5a9de014baaa66ba7 233 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 33 206 8.9E-19 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS41980 587d8af57fd6cbff5c4a1ea04a3eb2e4 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS41980 587d8af57fd6cbff5c4a1ea04a3eb2e4 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS41980 587d8af57fd6cbff5c4a1ea04a3eb2e4 208 Gene3D G3DSA:1.10.260.40 48 107 3.0E-12 T 28-03-2018 SMD44_RS41980 587d8af57fd6cbff5c4a1ea04a3eb2e4 208 Gene3D G3DSA:1.10.10.60 2 47 4.1E-15 T 28-03-2018 SMD44_RS41980 587d8af57fd6cbff5c4a1ea04a3eb2e4 208 SUPERFAMILY SSF46689 14 76 1.25E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS41980 587d8af57fd6cbff5c4a1ea04a3eb2e4 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 7.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS18495 559b6fdb03d8019c8c493ff1bed5eacd 175 Pfam PF12802 MarR family 58 112 1.5E-11 T 28-03-2018 SMD44_RS18495 559b6fdb03d8019c8c493ff1bed5eacd 175 Gene3D G3DSA:1.10.10.10 3 159 8.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18495 559b6fdb03d8019c8c493ff1bed5eacd 175 SUPERFAMILY SSF46785 21 158 1.21E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS18495 559b6fdb03d8019c8c493ff1bed5eacd 175 SMART SM00347 49 148 3.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS43065 ffd2ddc2eaf4a3eb34f92c22fb44f48b 140 Pfam PF07811 TadE-like protein 12 52 1.9E-9 T 28-03-2018 IPR012495 TadE-like SMD44_RS43655 75cfd159972dacc7fea638d130e13760 190 SUPERFAMILY SSF160631 7 127 9.81E-6 T 28-03-2018 SMD44_RS43655 75cfd159972dacc7fea638d130e13760 190 Gene3D G3DSA:3.40.1580.10 1 155 8.7E-17 T 28-03-2018 SMD44_RS43655 75cfd159972dacc7fea638d130e13760 190 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 27 86 2.6E-7 T 28-03-2018 IPR018958 Knr4/Smi1-like domain SMD44_RS18840 f7ba04a0bf1700d7fc35d3c37147cba6 334 Pfam PF00480 ROK family 5 301 2.7E-62 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMD44_RS18840 f7ba04a0bf1700d7fc35d3c37147cba6 334 SUPERFAMILY SSF53067 4 305 1.53E-55 T 28-03-2018 SMD44_RS18840 f7ba04a0bf1700d7fc35d3c37147cba6 334 Gene3D G3DSA:3.30.420.40 125 314 3.8E-52 T 28-03-2018 SMD44_RS18840 f7ba04a0bf1700d7fc35d3c37147cba6 334 Gene3D G3DSA:3.30.420.40 1 124 2.3E-30 T 28-03-2018 SMD44_RS09830 08f90f9961844c91facf3ff935bfd45b 269 SUPERFAMILY SSF51735 1 241 1.45E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS09830 08f90f9961844c91facf3ff935bfd45b 269 Gene3D G3DSA:3.40.50.720 3 230 2.4E-34 T 28-03-2018 SMD44_RS09830 08f90f9961844c91facf3ff935bfd45b 269 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 166 1.9E-19 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS07555 12f86fa545f03d2d9e403280cac807f3 148 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 27 142 1.2E-41 T 28-03-2018 IPR013434 Conserved hypothetical protein CHP02611 SMD44_RS07555 12f86fa545f03d2d9e403280cac807f3 148 Pfam PF09656 Putative transmembrane protein (PGPGW) 46 98 1.5E-22 T 28-03-2018 IPR019099 Uncharacterised protein family PGPGW, transmembrane SMD44_RS06205 c51c33dbaa50868cf2f7e25fba0b27f1 223 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 56 165 3.8E-20 T 28-03-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated SMD44_RS06205 c51c33dbaa50868cf2f7e25fba0b27f1 223 Gene3D G3DSA:3.90.550.10 14 221 4.8E-13 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS06205 c51c33dbaa50868cf2f7e25fba0b27f1 223 SUPERFAMILY SSF53448 19 203 3.54E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS21255 0aeed4c30e26f9f4030939e65d7d7383 252 Pfam PF03777 Small secreted domain (DUF320) 156 207 8.6E-19 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS21255 0aeed4c30e26f9f4030939e65d7d7383 252 Pfam PF03777 Small secreted domain (DUF320) 25 78 6.7E-22 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS41195 ec758ad8e513af0d0ffd01047fa2d5c7 292 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 30 158 3.6E-14 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMD44_RS41195 ec758ad8e513af0d0ffd01047fa2d5c7 292 SUPERFAMILY SSF53901 12 193 2.13E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41195 ec758ad8e513af0d0ffd01047fa2d5c7 292 Gene3D G3DSA:3.40.47.10 2 203 1.6E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS41195 ec758ad8e513af0d0ffd01047fa2d5c7 292 SUPERFAMILY SSF53901 168 253 6.5E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD44_RS30630 c018d46db323bf8b262a7f08950303b8 276 Gene3D G3DSA:3.40.50.300 8 230 9.2E-50 T 28-03-2018 SMD44_RS30630 c018d46db323bf8b262a7f08950303b8 276 Pfam PF00005 ABC transporter 25 174 5.9E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS30630 c018d46db323bf8b262a7f08950303b8 276 SUPERFAMILY SSF52540 9 226 1.77E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS30630 c018d46db323bf8b262a7f08950303b8 276 SMART SM00382 34 222 1.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS31825 2937ef2c4f589bc0c488635f940e8819 282 Pfam PF13349 Putative adhesin 24 279 2.7E-11 T 28-03-2018 IPR025164 Putative adhesin SMD44_RS00900 b330e3b6419ad1bbd2b6fce28aa5c6e8 247 Gene3D G3DSA:2.130.10.130 25 203 1.2E-9 T 28-03-2018 SMD44_RS00900 b330e3b6419ad1bbd2b6fce28aa5c6e8 247 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 60 126 1.0E-8 T 28-03-2018 SMD44_RS00900 b330e3b6419ad1bbd2b6fce28aa5c6e8 247 SUPERFAMILY SSF69318 50 209 6.41E-12 T 28-03-2018 SMD44_RS20190 56389820dfd5c21f8c00f9470a510680 211 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 87 177 1.0E-15 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD44_RS25905 56ecf13fe59f4cad8e8553f6b4103e83 159 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 30 104 5.9E-5 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS25905 56ecf13fe59f4cad8e8553f6b4103e83 159 Gene3D G3DSA:2.30.110.10 6 136 9.0E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS25905 56ecf13fe59f4cad8e8553f6b4103e83 159 SUPERFAMILY SSF50475 13 132 1.94E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS38070 4cef46653f13d2645a8479c13dff0449 231 Pfam PF00072 Response regulator receiver domain 3 120 1.5E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS38070 4cef46653f13d2645a8479c13dff0449 231 SMART SM00862 152 227 4.8E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS38070 4cef46653f13d2645a8479c13dff0449 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 1.1E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD44_RS38070 4cef46653f13d2645a8479c13dff0449 231 SMART SM00448 1 119 2.2E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD44_RS38070 4cef46653f13d2645a8479c13dff0449 231 SUPERFAMILY SSF52172 1 178 7.7E-36 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS38070 4cef46653f13d2645a8479c13dff0449 231 Gene3D G3DSA:3.40.50.2300 1 123 5.3E-33 T 28-03-2018 SMD44_RS38070 4cef46653f13d2645a8479c13dff0449 231 Gene3D G3DSA:1.10.10.10 124 231 2.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13170 eb9d9c7de76f41476846558595ba41a8 198 SUPERFAMILY SSF160631 7 126 2.49E-6 T 28-03-2018 SMD44_RS13170 eb9d9c7de76f41476846558595ba41a8 198 Gene3D G3DSA:3.40.1580.10 1 189 2.8E-12 T 28-03-2018 SMD44_RS20880 645c9a842c85d3aae42601415f9c4cd7 126 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 115 1.0E-30 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV SMD44_RS06010 b7ffbb906f7d3700a285b602662df769 247 Pfam PF12679 ABC-2 family transporter protein 65 246 3.6E-8 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS22900 3b0daba2401980417cb587f193a2e4f5 69 Pfam PF14117 Domain of unknown function (DUF4287) 8 64 2.3E-28 T 28-03-2018 IPR025629 Protein of unknown function DUF4287 SMD44_RS11555 9ebcfb80f9113c936989e1612dbf16ee 173 Pfam PF14024 Protein of unknown function (DUF4240) 1 128 5.8E-46 T 28-03-2018 IPR025334 Domain of unknown function (DUF4240 SMD44_RS37310 e8ca1fd746dc7239b6ae4d6781e1d444 276 Pfam PF01522 Polysaccharide deacetylase 89 205 1.3E-33 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD44_RS37310 e8ca1fd746dc7239b6ae4d6781e1d444 276 SUPERFAMILY SSF88713 80 268 3.15E-58 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD44_RS37310 e8ca1fd746dc7239b6ae4d6781e1d444 276 Gene3D G3DSA:3.20.20.370 73 273 1.6E-52 T 28-03-2018 SMD44_RS21140 978cfb99c9be4faecfde7d166984c5c6 374 ProSitePatterns PS00618 RecF protein signature 2. 317 335 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SMD44_RS21140 978cfb99c9be4faecfde7d166984c5c6 374 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 349 4.5E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SMD44_RS21140 978cfb99c9be4faecfde7d166984c5c6 374 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 374 97.178 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SMD44_RS21140 978cfb99c9be4faecfde7d166984c5c6 374 SUPERFAMILY SSF52540 250 348 1.68E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21140 978cfb99c9be4faecfde7d166984c5c6 374 SUPERFAMILY SSF52540 1 223 1.68E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS21140 978cfb99c9be4faecfde7d166984c5c6 374 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SMD44_RS21140 978cfb99c9be4faecfde7d166984c5c6 374 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 360 2.4E-127 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SMD44_RS21140 978cfb99c9be4faecfde7d166984c5c6 374 Gene3D G3DSA:3.40.50.300 1 358 1.1E-30 T 28-03-2018 SMD44_RS40875 aff3b0cedb7150172dc737c13d785394 290 Pfam PF12833 Helix-turn-helix domain 179 245 4.9E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS40875 aff3b0cedb7150172dc737c13d785394 290 SUPERFAMILY SSF51182 14 178 8.3E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS40875 aff3b0cedb7150172dc737c13d785394 290 SMART SM00342 171 252 2.1E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD44_RS40875 aff3b0cedb7150172dc737c13d785394 290 Pfam PF02311 AraC-like ligand binding domain 23 139 5.5E-6 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD44_RS40875 aff3b0cedb7150172dc737c13d785394 290 Gene3D G3DSA:2.60.120.10 13 90 6.8E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS40875 aff3b0cedb7150172dc737c13d785394 290 SUPERFAMILY SSF46689 207 245 6.72E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS40875 aff3b0cedb7150172dc737c13d785394 290 Gene3D G3DSA:1.10.10.60 151 208 1.8E-12 T 28-03-2018 SMD44_RS40875 aff3b0cedb7150172dc737c13d785394 290 Gene3D G3DSA:1.10.10.60 209 248 4.3E-5 T 28-03-2018 SMD44_RS21210 095ae77f8023e182e64c61ea0219de1c 293 SUPERFAMILY SSF55729 169 289 4.96E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS21210 095ae77f8023e182e64c61ea0219de1c 293 Gene3D G3DSA:3.40.630.30 5 111 4.2E-14 T 28-03-2018 SMD44_RS21210 095ae77f8023e182e64c61ea0219de1c 293 Gene3D G3DSA:3.40.630.30 112 292 1.5E-14 T 28-03-2018 SMD44_RS21210 095ae77f8023e182e64c61ea0219de1c 293 Pfam PF00583 Acetyltransferase (GNAT) family 27 97 2.5E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS21210 095ae77f8023e182e64c61ea0219de1c 293 SUPERFAMILY SSF55729 17 109 3.01E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS37290 184c5cb745443655efc81bf8e5fbcc65 187 SUPERFAMILY SSF53597 2 186 2.62E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS37290 184c5cb745443655efc81bf8e5fbcc65 187 Pfam PF01872 RibD C-terminal domain 3 180 1.4E-19 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS37290 184c5cb745443655efc81bf8e5fbcc65 187 Gene3D G3DSA:3.40.430.10 2 183 7.1E-37 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS23980 83e34d72aa06d1300cc9ab3f430af840 606 Gene3D G3DSA:2.60.40.10 457 526 1.1E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS23980 83e34d72aa06d1300cc9ab3f430af840 606 Gene3D G3DSA:1.10.1740.10 33 109 2.5E-5 T 28-03-2018 SMD44_RS23980 83e34d72aa06d1300cc9ab3f430af840 606 Gene3D G3DSA:1.10.10.10 121 238 6.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS32550 3aafeb6c3bba8cf6bfb77118d81d2e61 320 SUPERFAMILY SSF81606 22 82 3.4E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS32550 3aafeb6c3bba8cf6bfb77118d81d2e61 320 SUPERFAMILY SSF81606 130 288 3.4E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS32550 3aafeb6c3bba8cf6bfb77118d81d2e61 320 Gene3D G3DSA:3.60.40.10 14 288 2.2E-12 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMD44_RS32550 3aafeb6c3bba8cf6bfb77118d81d2e61 320 Pfam PF13672 Protein phosphatase 2C 27 272 1.4E-30 T 28-03-2018 SMD44_RS25845 80ae5f8d2d35dce31f85157ca708d479 1091 Gene3D G3DSA:3.30.200.20 28 161 1.7E-4 T 28-03-2018 SMD44_RS25845 80ae5f8d2d35dce31f85157ca708d479 1091 SMART SM00220 23 756 8.6E-8 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS25845 80ae5f8d2d35dce31f85157ca708d479 1091 Gene3D G3DSA:1.10.510.10 162 771 6.3E-43 T 28-03-2018 SMD44_RS25845 80ae5f8d2d35dce31f85157ca708d479 1091 Pfam PF07714 Protein tyrosine kinase 110 203 2.2E-7 T 28-03-2018 IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain GO:0004672|GO:0006468 SMD44_RS25845 80ae5f8d2d35dce31f85157ca708d479 1091 SUPERFAMILY SSF56112 112 206 3.08E-20 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS25845 80ae5f8d2d35dce31f85157ca708d479 1091 SUPERFAMILY SSF56112 647 771 3.08E-20 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS25845 80ae5f8d2d35dce31f85157ca708d479 1091 Gene3D G3DSA:3.40.1000.10 952 1089 3.4E-10 T 28-03-2018 SMD44_RS20850 c8e12974d6ec4d0f5687c41ee632dcce 593 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 135 559 2.7E-212 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMD44_RS20850 c8e12974d6ec4d0f5687c41ee632dcce 593 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 135 562 55.461 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMD44_RS20850 c8e12974d6ec4d0f5687c41ee632dcce 593 Pfam PF01964 Radical SAM ThiC family 136 556 2.8E-198 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMD44_RS20850 c8e12974d6ec4d0f5687c41ee632dcce 593 Pfam PF13667 ThiC-associated domain 26 89 1.1E-22 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMD44_RS18180 b0475409d6fb6f1b52e79b5acbf15ee0 261 Pfam PF00293 NUDIX domain 111 238 1.1E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS18180 b0475409d6fb6f1b52e79b5acbf15ee0 261 SUPERFAMILY SSF55811 103 240 2.44E-17 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS18180 b0475409d6fb6f1b52e79b5acbf15ee0 261 Gene3D G3DSA:3.90.79.10 106 245 3.7E-18 T 28-03-2018 SMD44_RS24320 5526237cd3e72655f38e538fd639e81d 491 Gene3D G3DSA:3.90.1310.10 17 140 1.6E-18 T 28-03-2018 SMD44_RS24320 5526237cd3e72655f38e538fd639e81d 491 SUPERFAMILY SSF56601 138 489 3.12E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS24320 5526237cd3e72655f38e538fd639e81d 491 Pfam PF00905 Penicillin binding protein transpeptidase domain 157 485 8.0E-66 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD44_RS24320 5526237cd3e72655f38e538fd639e81d 491 Gene3D G3DSA:3.40.710.10 141 491 1.0E-82 T 28-03-2018 SMD44_RS22285 453008d6461aab1c4311a4b5f2a26ef8 185 Pfam PF05099 Tellurite resistance protein TerB 48 183 3.3E-29 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal SMD44_RS22285 453008d6461aab1c4311a4b5f2a26ef8 185 SUPERFAMILY SSF158682 49 184 1.44E-24 T 28-03-2018 SMD44_RS22285 453008d6461aab1c4311a4b5f2a26ef8 185 Gene3D G3DSA:1.10.3680.10 36 184 1.1E-25 T 28-03-2018 IPR029024 TerB-like SMD44_RS12215 553aa2ae094a3c7cc58f1d93c9485f66 480 SUPERFAMILY SSF50249 23 415 1.26E-86 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS12215 553aa2ae094a3c7cc58f1d93c9485f66 480 Gene3D G3DSA:2.40.50.140 417 480 4.7E-21 T 28-03-2018 SMD44_RS12215 553aa2ae094a3c7cc58f1d93c9485f66 480 SMART SM00955 52 371 3.1E-53 T 28-03-2018 SMD44_RS12215 553aa2ae094a3c7cc58f1d93c9485f66 480 Pfam PF00773 RNB domain 54 363 1.6E-39 T 28-03-2018 SMD44_RS14290 292f2e4e7162f4c7b7d800ccfdb5f124 194 Pfam PF07336 Putative stress-induced transcription regulator 17 144 5.9E-16 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator SMD44_RS14290 292f2e4e7162f4c7b7d800ccfdb5f124 194 Pfam PF11706 CGNR zinc finger 148 190 1.2E-18 T 28-03-2018 IPR021005 Zinc finger, CGNR SMD44_RS14290 292f2e4e7162f4c7b7d800ccfdb5f124 194 Gene3D G3DSA:1.10.3300.10 8 193 1.4E-43 T 28-03-2018 IPR023286 ABATE domain SMD44_RS14290 292f2e4e7162f4c7b7d800ccfdb5f124 194 SUPERFAMILY SSF160904 9 190 1.83E-39 T 28-03-2018 SMD44_RS30515 63decbb5f4ab5371a8f60fb8ce4880b9 269 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 39 55 4.7E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30515 63decbb5f4ab5371a8f60fb8ce4880b9 269 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 4.7E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30515 63decbb5f4ab5371a8f60fb8ce4880b9 269 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 89 101 4.7E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30515 63decbb5f4ab5371a8f60fb8ce4880b9 269 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 27 184 9.6E-40 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD44_RS30515 63decbb5f4ab5371a8f60fb8ce4880b9 269 SUPERFAMILY SSF51306 39 186 7.85E-41 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30515 63decbb5f4ab5371a8f60fb8ce4880b9 269 Pfam PF00717 Peptidase S24-like 45 114 5.1E-13 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMD44_RS30515 63decbb5f4ab5371a8f60fb8ce4880b9 269 Gene3D G3DSA:2.10.109.10 35 191 1.6E-33 T 28-03-2018 SMD44_RS33025 68c61ddce46d3b3c6a7180306e244001 296 Gene3D G3DSA:3.30.390.50 167 291 1.3E-28 T 28-03-2018 SMD44_RS33025 68c61ddce46d3b3c6a7180306e244001 296 SUPERFAMILY SSF56176 2 164 2.91E-49 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD44_RS33025 68c61ddce46d3b3c6a7180306e244001 296 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 164 6.3E-46 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMD44_RS33025 68c61ddce46d3b3c6a7180306e244001 296 SUPERFAMILY SSF55447 171 284 3.4E-18 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD44_RS33025 68c61ddce46d3b3c6a7180306e244001 296 Gene3D G3DSA:3.30.43.10 5 51 1.9E-18 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD44_RS33025 68c61ddce46d3b3c6a7180306e244001 296 SMART SM01092 171 281 2.2E-16 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD44_RS33025 68c61ddce46d3b3c6a7180306e244001 296 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 172 278 2.6E-9 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD44_RS33025 68c61ddce46d3b3c6a7180306e244001 296 Gene3D G3DSA:3.30.465.10 52 166 6.3E-31 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD44_RS07935 d77e7c31cd26009855a5f8b1c92a30e8 241 Pfam PF07179 SseB protein N-terminal domain 22 142 1.1E-25 T 28-03-2018 IPR009839 SseB protein N-terminal domain SMD44_RS25140 1841d5340a3c63fb1cea5c05f7132f48 417 SUPERFAMILY SSF89392 135 305 1.65E-14 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD44_RS25140 1841d5340a3c63fb1cea5c05f7132f48 417 Gene3D G3DSA:2.50.20.10 58 307 6.3E-52 T 28-03-2018 SMD44_RS29400 7606b13ebafc854066b2460c9265d3a4 311 Gene3D G3DSA:1.10.1040.10 191 310 2.5E-9 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD44_RS29400 7606b13ebafc854066b2460c9265d3a4 311 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 26 180 2.6E-21 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD44_RS29400 7606b13ebafc854066b2460c9265d3a4 311 SUPERFAMILY SSF51735 26 180 9.4E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS29400 7606b13ebafc854066b2460c9265d3a4 311 PIRSF PIRSF000103 18 311 8.6E-38 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD44_RS29400 7606b13ebafc854066b2460c9265d3a4 311 Gene3D G3DSA:3.40.50.720 2 190 2.5E-27 T 28-03-2018 SMD44_RS08990 b2561c325ef532176df56f44f96c7dd0 421 Pfam PF13458 Periplasmic binding protein 37 398 7.2E-53 T 28-03-2018 IPR028081 Leucine-binding protein domain SMD44_RS08990 b2561c325ef532176df56f44f96c7dd0 421 Gene3D G3DSA:3.40.50.2300 237 383 3.7E-9 T 28-03-2018 SMD44_RS08990 b2561c325ef532176df56f44f96c7dd0 421 Gene3D G3DSA:3.40.50.2300 35 236 3.7E-19 T 28-03-2018 SMD44_RS08990 b2561c325ef532176df56f44f96c7dd0 421 SUPERFAMILY SSF53822 37 403 2.12E-39 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS28275 4984140bf23d0b4042e49dc29f3b54cf 451 SMART SM00471 239 374 1.7E-13 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS28275 4984140bf23d0b4042e49dc29f3b54cf 451 SUPERFAMILY SSF109604 228 404 6.28E-38 T 28-03-2018 SMD44_RS28275 4984140bf23d0b4042e49dc29f3b54cf 451 Pfam PF01966 HD domain 245 365 2.9E-21 T 28-03-2018 IPR006674 HD domain SMD44_RS28275 4984140bf23d0b4042e49dc29f3b54cf 451 TIGRFAM TIGR00277 HDIG: HDIG domain 244 333 5.3E-8 T 28-03-2018 IPR006675 HDIG domain SMD44_RS28275 4984140bf23d0b4042e49dc29f3b54cf 451 Gene3D G3DSA:1.10.3210.10 214 409 2.7E-49 T 28-03-2018 SMD44_RS26780 0167180c54fca34e4a31f7bf107e47c8 384 Gene3D G3DSA:1.10.3470.10 2 342 1.6E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS26780 0167180c54fca34e4a31f7bf107e47c8 384 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 336 9.7E-43 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS21710 393d445dd4a7a63253956f44954acf14 563 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 7 562 9.7E-296 T 28-03-2018 IPR011975 Phenylacetic acid degradation protein PaaN2 SMD44_RS21710 393d445dd4a7a63253956f44954acf14 563 Pfam PF00171 Aldehyde dehydrogenase family 94 479 1.1E-31 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS21710 393d445dd4a7a63253956f44954acf14 563 Gene3D G3DSA:3.40.605.10 91 331 2.2E-34 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS21710 393d445dd4a7a63253956f44954acf14 563 SUPERFAMILY SSF53720 72 539 1.7E-54 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS21710 393d445dd4a7a63253956f44954acf14 563 Gene3D G3DSA:3.40.309.10 332 534 1.1E-21 T 28-03-2018 SMD44_RS22105 de9d07fac31c824201c6e19f3c50ddab 373 SUPERFAMILY SSF53335 8 63 2.6E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS22105 de9d07fac31c824201c6e19f3c50ddab 373 SUPERFAMILY SSF53335 106 228 2.6E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS22105 de9d07fac31c824201c6e19f3c50ddab 373 TIGRFAM TIGR04188 methyltr_grsp: methyltransferase, ATP-grasp peptide maturase system 14 369 1.1E-124 T 28-03-2018 IPR026448 Methyltransferase, ATP-grasp peptide maturase system SMD44_RS22105 de9d07fac31c824201c6e19f3c50ddab 373 Gene3D G3DSA:3.40.50.150 14 253 1.9E-24 T 28-03-2018 SMD44_RS22105 de9d07fac31c824201c6e19f3c50ddab 373 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 101 233 7.1E-22 T 28-03-2018 SMD44_RS06630 9279a904a2a90c6ae63ace03ab04a1a8 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 1.6E-34 T 28-03-2018 IPR009709 Protein of unknown function DUF1290 SMD44_RS06630 9279a904a2a90c6ae63ace03ab04a1a8 110 PIRSF PIRSF018579 1 110 5.1E-47 T 28-03-2018 IPR009709 Protein of unknown function DUF1290 SMD44_RS42640 58bb436782e077f238739efda5eebdbc 384 SUPERFAMILY SSF53335 57 209 6.41E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS42640 58bb436782e077f238739efda5eebdbc 384 Gene3D G3DSA:3.40.50.150 1 268 7.9E-29 T 28-03-2018 SMD44_RS42640 58bb436782e077f238739efda5eebdbc 384 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 90 210 1.3E-24 T 28-03-2018 SMD44_RS07725 f95f1b5db66860becbbd4d2ca71ac278 229 Pfam PF01553 Acyltransferase 27 157 3.4E-21 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS07725 f95f1b5db66860becbbd4d2ca71ac278 229 SUPERFAMILY SSF69593 7 226 6.93E-46 T 28-03-2018 SMD44_RS07725 f95f1b5db66860becbbd4d2ca71ac278 229 SMART SM00563 41 160 5.4E-32 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD44_RS07725 f95f1b5db66860becbbd4d2ca71ac278 229 Gene3D G3DSA:3.40.1130.10 11 229 4.8E-51 T 28-03-2018 SMD44_RS40470 9361cfca26c960405719a0609f95a4e6 227 Gene3D G3DSA:1.10.260.40 60 188 4.3E-5 T 28-03-2018 SMD44_RS40470 9361cfca26c960405719a0609f95a4e6 227 SUPERFAMILY SSF47413 102 156 3.49E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS05660 1c0a87d6a815bec6d9d74ae94ad1f27f 61 SUPERFAMILY SSF57938 8 50 8.37E-5 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD44_RS05440 54a48162c03c69b55a414789677a8e62 268 SUPERFAMILY SSF51182 31 136 1.07E-10 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS05440 54a48162c03c69b55a414789677a8e62 268 Gene3D G3DSA:2.60.120.10 5 208 7.7E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS11100 bd3497bc7b7ef2d9437d23bc6a8f95e1 282 Gene3D G3DSA:3.40.50.150 19 276 5.2E-41 T 28-03-2018 SMD44_RS11100 bd3497bc7b7ef2d9437d23bc6a8f95e1 282 Pfam PF13489 Methyltransferase domain 43 216 7.1E-16 T 28-03-2018 SMD44_RS11100 bd3497bc7b7ef2d9437d23bc6a8f95e1 282 SUPERFAMILY SSF53335 52 226 2.28E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS36160 2879b4d779cf3637ed5282dec91d8425 282 Pfam PF13349 Putative adhesin 21 276 6.1E-9 T 28-03-2018 IPR025164 Putative adhesin SMD44_RS23740 80c73351c7701ab3d0017524b1b17064 608 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 249 555 1.6E-105 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD44_RS23740 80c73351c7701ab3d0017524b1b17064 608 Gene3D G3DSA:3.40.630.30 337 552 3.2E-5 T 28-03-2018 SMD44_RS23740 80c73351c7701ab3d0017524b1b17064 608 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 26 228 6.8E-14 T 28-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 SMD44_RS26270 0228881555f827560c458674d6ebdb45 463 SUPERFAMILY SSF82866 195 426 3.01E-29 T 28-03-2018 SMD44_RS26270 0228881555f827560c458674d6ebdb45 463 Pfam PF03176 MMPL family 193 437 1.9E-37 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS26270 0228881555f827560c458674d6ebdb45 463 Gene3D G3DSA:1.20.1640.10 201 425 1.1E-32 T 28-03-2018 SMD44_RS27805 31b742c813e9499eb7d3243e3334be57 384 Gene3D G3DSA:3.40.640.10 61 277 2.6E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS27805 31b742c813e9499eb7d3243e3334be57 384 Gene3D G3DSA:3.90.1150.10 278 384 3.5E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS27805 31b742c813e9499eb7d3243e3334be57 384 SUPERFAMILY SSF53383 18 384 3.4E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS27805 31b742c813e9499eb7d3243e3334be57 384 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 20 384 1.6E-179 T 28-03-2018 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria SMD44_RS27805 31b742c813e9499eb7d3243e3334be57 384 Pfam PF00155 Aminotransferase class I and II 42 383 2.2E-42 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS40955 733be0c45d165d936598df734c4d8e30 769 Pfam PF01032 FecCD transport family 455 761 4.1E-74 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS40955 733be0c45d165d936598df734c4d8e30 769 Pfam PF01032 FecCD transport family 52 364 1.3E-78 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS40955 733be0c45d165d936598df734c4d8e30 769 SUPERFAMILY SSF81345 37 363 9.81E-68 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS40955 733be0c45d165d936598df734c4d8e30 769 SUPERFAMILY SSF81345 439 761 3.79E-60 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS40955 733be0c45d165d936598df734c4d8e30 769 Gene3D G3DSA:1.10.3470.10 440 769 8.4E-55 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS40955 733be0c45d165d936598df734c4d8e30 769 Gene3D G3DSA:1.10.3470.10 37 372 1.6E-53 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS02900 4c1731e0b1bbb92534e94066ca84ab78 165 Pfam PF01638 HxlR-like helix-turn-helix 19 105 1.8E-21 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS02900 4c1731e0b1bbb92534e94066ca84ab78 165 Gene3D G3DSA:1.10.10.10 1 164 3.7E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS02900 4c1731e0b1bbb92534e94066ca84ab78 165 SUPERFAMILY SSF46785 5 144 7.63E-42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20120 fe01bae6f33fed23a3f2af40de83180f 82 Pfam PF13545 Crp-like helix-turn-helix domain 10 76 5.4E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD44_RS20120 fe01bae6f33fed23a3f2af40de83180f 82 SUPERFAMILY SSF46785 8 78 1.23E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20120 fe01bae6f33fed23a3f2af40de83180f 82 Gene3D G3DSA:1.10.10.10 7 82 1.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08060 41344d924ca6fd55d1ce62d1cf5facaf 116 Pfam PF05331 Protein of unknown function (DUF742) 11 116 6.9E-31 T 28-03-2018 IPR007995 Protein of unknown function DUF742 SMD44_RS08895 a29379ac6c6306dd8731da74a8ee1ee6 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 338 1.2E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS08895 a29379ac6c6306dd8731da74a8ee1ee6 338 SUPERFAMILY SSF161098 118 337 1.3E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS08895 a29379ac6c6306dd8731da74a8ee1ee6 338 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 77 5.2E-5 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD44_RS08895 a29379ac6c6306dd8731da74a8ee1ee6 338 Gene3D G3DSA:1.10.3720.10 35 326 1.1E-41 T 28-03-2018 SMD44_RS25915 756fdd76e69f85d27cbee9b6fe7aafa6 421 Gene3D G3DSA:2.60.40.10 328 414 3.0E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS02435 c6d13a94d0f77bca4208b69b815320a7 212 SUPERFAMILY SSF51735 1 203 6.96E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02435 c6d13a94d0f77bca4208b69b815320a7 212 Gene3D G3DSA:3.40.50.720 1 209 2.1E-20 T 28-03-2018 SMD44_RS02435 c6d13a94d0f77bca4208b69b815320a7 212 Pfam PF13460 NAD(P)H-binding 7 201 1.5E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS24460 a37d589ec15861ba46a1b95b3aba182e 279 SUPERFAMILY SSF47413 25 72 1.1E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS24460 a37d589ec15861ba46a1b95b3aba182e 279 Pfam PF13560 Helix-turn-helix domain 1 78 2.7E-17 T 28-03-2018 SMD44_RS24460 a37d589ec15861ba46a1b95b3aba182e 279 Gene3D G3DSA:1.10.260.40 1 94 5.6E-15 T 28-03-2018 SMD44_RS24460 a37d589ec15861ba46a1b95b3aba182e 279 SMART SM00530 4 77 9.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS32755 f80976874862e147015a7cef74da0e6b 383 Pfam PF01066 CDP-alcohol phosphatidyltransferase 51 117 8.3E-12 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD44_RS32755 f80976874862e147015a7cef74da0e6b 383 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 95 117 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD44_RS28270 58c0cd3e61d6feadf622556e01acdb7e 102 Pfam PF13490 Putative zinc-finger 11 44 1.4E-8 T 28-03-2018 IPR027383 Putative zinc-finger SMD44_RS28270 58c0cd3e61d6feadf622556e01acdb7e 102 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 84 5.8E-31 T 28-03-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA SMD44_RS28270 58c0cd3e61d6feadf622556e01acdb7e 102 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 85 7.8E-37 T 28-03-2018 IPR014295 Anti-sigma factor SMD44_RS41675 6801b12ebfa5d0abb4e5b6e42362d03f 361 SUPERFAMILY SSF102114 17 305 1.27E-35 T 28-03-2018 SMD44_RS41675 6801b12ebfa5d0abb4e5b6e42362d03f 361 Gene3D G3DSA:3.20.20.70 9 351 6.1E-33 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS41675 6801b12ebfa5d0abb4e5b6e42362d03f 361 Pfam PF13353 4Fe-4S single cluster domain 29 134 2.3E-7 T 28-03-2018 SMD44_RS41675 6801b12ebfa5d0abb4e5b6e42362d03f 361 Pfam PF04055 Radical SAM superfamily 27 185 1.1E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD44_RS40070 3541892c1da109c1a81f34d81b38809c 313 Pfam PF02574 Homocysteine S-methyltransferase 27 310 9.5E-75 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD44_RS40070 3541892c1da109c1a81f34d81b38809c 313 PIRSF PIRSF037505 18 241 3.8E-6 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 SMD44_RS40070 3541892c1da109c1a81f34d81b38809c 313 PIRSF PIRSF037505 266 313 0.43 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 SMD44_RS40070 3541892c1da109c1a81f34d81b38809c 313 Gene3D G3DSA:3.20.20.330 7 313 1.3E-99 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD44_RS40070 3541892c1da109c1a81f34d81b38809c 313 SUPERFAMILY SSF82282 19 313 4.84E-81 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD44_RS04890 35a605859c4826415dc8fd612ad87e7d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 4.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS04890 35a605859c4826415dc8fd612ad87e7d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 4.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS04890 35a605859c4826415dc8fd612ad87e7d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 4.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS04890 35a605859c4826415dc8fd612ad87e7d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 4.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS04890 35a605859c4826415dc8fd612ad87e7d 256 Gene3D G3DSA:3.40.50.720 5 254 1.1E-34 T 28-03-2018 SMD44_RS04890 35a605859c4826415dc8fd612ad87e7d 256 Pfam PF00106 short chain dehydrogenase 18 187 3.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS04890 35a605859c4826415dc8fd612ad87e7d 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS04890 35a605859c4826415dc8fd612ad87e7d 256 SUPERFAMILY SSF51735 10 251 4.72E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS32255 db5e5718135f8a85ccfcd7847c6cec36 200 SUPERFAMILY SSF52980 14 171 6.97E-16 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS32255 db5e5718135f8a85ccfcd7847c6cec36 200 Pfam PF05685 Putative restriction endonuclease 33 193 1.4E-16 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS32255 db5e5718135f8a85ccfcd7847c6cec36 200 Gene3D G3DSA:3.90.1570.10 12 197 2.4E-21 T 28-03-2018 SMD44_RS12165 64b182ad20ad99b87f6737927234326c 181 SUPERFAMILY SSF47598 117 180 7.56E-10 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMD44_RS12165 64b182ad20ad99b87f6737927234326c 181 Gene3D G3DSA:1.10.1220.10 117 154 3.1E-12 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS09440 69d4a4190bd5008f23ff315bbc14b2b9 344 Pfam PF05425 Copper resistance protein D 237 335 3.0E-13 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 SMD44_RS38205 af39ccf778c30cde5d7834c5db924850 335 SUPERFAMILY SSF47413 83 135 4.15E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS38205 af39ccf778c30cde5d7834c5db924850 335 Pfam PF13560 Helix-turn-helix domain 60 139 5.8E-18 T 28-03-2018 SMD44_RS38205 af39ccf778c30cde5d7834c5db924850 335 SMART SM00530 64 136 5.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS38205 af39ccf778c30cde5d7834c5db924850 335 Gene3D G3DSA:1.10.260.40 54 146 3.4E-17 T 28-03-2018 SMD44_RS17980 9e6e5c697fd402f70033ffb8deafcfaa 148 SUPERFAMILY SSF50249 10 139 4.28E-33 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS17980 9e6e5c697fd402f70033ffb8deafcfaa 148 Gene3D G3DSA:2.40.50.140 66 138 5.3E-15 T 28-03-2018 SMD44_RS17980 9e6e5c697fd402f70033ffb8deafcfaa 148 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 63 131 2.7E-18 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMD44_RS17980 9e6e5c697fd402f70033ffb8deafcfaa 148 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 24 59 2.3E-10 T 28-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMD44_RS02655 a62c556d039619d18498a787a215cd4c 224 Pfam PF00174 Oxidoreductase molybdopterin binding domain 33 167 1.2E-21 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS02655 a62c556d039619d18498a787a215cd4c 224 SUPERFAMILY SSF56524 3 177 3.27E-32 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS02655 a62c556d039619d18498a787a215cd4c 224 Gene3D G3DSA:3.90.420.10 2 193 6.6E-36 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS14055 d9cdeb2b7fc3a7ab0c95746520f0dcd8 224 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 156 1.7E-18 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SMD44_RS14055 d9cdeb2b7fc3a7ab0c95746520f0dcd8 224 Pfam PF04093 rod shape-determining protein MreD 5 92 2.6E-5 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SMD44_RS12955 863d198d673fc0c0852bb95ef3767374 173 SUPERFAMILY SSF55729 8 156 3.6E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS12955 863d198d673fc0c0852bb95ef3767374 173 Pfam PF00583 Acetyltransferase (GNAT) family 35 126 6.6E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS12955 863d198d673fc0c0852bb95ef3767374 173 Gene3D G3DSA:3.40.630.30 1 172 5.0E-17 T 28-03-2018 SMD44_RS15970 a0f181c5c5d4f8ea174fff3a42203af3 452 Gene3D G3DSA:1.20.1250.20 24 216 8.8E-16 T 28-03-2018 SMD44_RS15970 a0f181c5c5d4f8ea174fff3a42203af3 452 Pfam PF07690 Major Facilitator Superfamily 42 388 9.2E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS15970 a0f181c5c5d4f8ea174fff3a42203af3 452 SUPERFAMILY SSF103473 11 429 4.58E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS15970 a0f181c5c5d4f8ea174fff3a42203af3 452 Gene3D G3DSA:1.20.1250.20 220 439 3.6E-23 T 28-03-2018 SMD44_RS17725 66db023026b6d5d27cd96ee8814bc47b 82 Pfam PF04149 Domain of unknown function (DUF397) 6 24 3.1E-7 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS17725 66db023026b6d5d27cd96ee8814bc47b 82 Pfam PF04149 Domain of unknown function (DUF397) 26 77 2.5E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS18745 61d3aaa79254c365d572b1d6ed2496df 404 Pfam PF02687 FtsX-like permease family 310 397 1.7E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS18745 61d3aaa79254c365d572b1d6ed2496df 404 Pfam PF12704 MacB-like periplasmic core domain 38 217 2.8E-14 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS42760 2732844f5fa71e49ce2762ef20aa1183 217 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 31 210 29.236 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMD44_RS42760 2732844f5fa71e49ce2762ef20aa1183 217 Gene3D G3DSA:1.10.286.10 33 78 2.5E-14 T 28-03-2018 SMD44_RS42760 2732844f5fa71e49ce2762ef20aa1183 217 Pfam PF01227 GTP cyclohydrolase I 38 208 2.6E-51 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMD44_RS42760 2732844f5fa71e49ce2762ef20aa1183 217 Gene3D G3DSA:3.30.1130.10 79 211 4.8E-40 T 28-03-2018 SMD44_RS42760 2732844f5fa71e49ce2762ef20aa1183 217 SUPERFAMILY SSF55620 30 209 5.56E-51 T 28-03-2018 SMD44_RS41515 90bd57a331b65e8e3bb9214bd33d328f 194 Pfam PF00156 Phosphoribosyl transferase domain 31 176 8.4E-24 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD44_RS41515 90bd57a331b65e8e3bb9214bd33d328f 194 Gene3D G3DSA:3.40.50.2020 25 182 7.4E-24 T 28-03-2018 SMD44_RS41515 90bd57a331b65e8e3bb9214bd33d328f 194 SUPERFAMILY SSF53271 15 175 1.18E-23 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like SMD44_RS04325 423960a959804a1756bc9ac14b8c4148 317 Gene3D G3DSA:3.90.25.10 167 310 6.4E-22 T 28-03-2018 SMD44_RS04325 423960a959804a1756bc9ac14b8c4148 317 SUPERFAMILY SSF51735 1 307 9.49E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS04325 423960a959804a1756bc9ac14b8c4148 317 Gene3D G3DSA:3.40.50.720 1 166 2.8E-29 T 28-03-2018 SMD44_RS04325 423960a959804a1756bc9ac14b8c4148 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 220 5.5E-37 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS37420 aab9f1af62a7eb9cea8ba2e6a0e7cb14 153 Gene3D G3DSA:2.30.110.10 8 146 9.5E-41 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS37420 aab9f1af62a7eb9cea8ba2e6a0e7cb14 153 Pfam PF04075 F420H(2)-dependent quinone reductase 14 145 2.9E-45 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD44_RS37420 aab9f1af62a7eb9cea8ba2e6a0e7cb14 153 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 35 144 1.7E-33 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD44_RS21545 7a4f8ea117019ae5e4fed7f3c131756b 115 Pfam PF13564 DoxX-like family 7 106 6.1E-17 T 28-03-2018 IPR032808 DoxX family SMD44_RS10025 db4034ddbba03b0c318421f603221bf8 271 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 32 261 9.1E-82 T 28-03-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 SMD44_RS10025 db4034ddbba03b0c318421f603221bf8 271 SUPERFAMILY SSF110710 8 265 7.85E-94 T 28-03-2018 SMD44_RS15390 c41137584427a33e39d672a647d43295 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 316 3.8E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15390 c41137584427a33e39d672a647d43295 319 SUPERFAMILY SSF161098 47 313 2.09E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS15390 c41137584427a33e39d672a647d43295 319 TIGRFAM TIGR03226 PhnU: 2-aminoethylphosphonate ABC transporter, permease protein 37 318 1.3E-97 T 28-03-2018 IPR017636 2-aminoethylphosphonate ABC transporter system, permease protein phnU GO:0016020|GO:0033223 SMD44_RS15390 c41137584427a33e39d672a647d43295 319 Gene3D G3DSA:1.10.3720.10 49 319 6.4E-47 T 28-03-2018 SMD44_RS01355 9164bb0ed31f7abc36938d48aa4648af 148 Pfam PF07883 Cupin domain 55 121 4.1E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel SMD44_RS01355 9164bb0ed31f7abc36938d48aa4648af 148 Gene3D G3DSA:2.60.120.10 15 146 1.7E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS01355 9164bb0ed31f7abc36938d48aa4648af 148 SUPERFAMILY SSF51182 34 143 6.09E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS42915 9afdd66c164e6a527e6ba984b9f51166 475 Pfam PF10935 Protein of unknown function (DUF2637) 35 178 7.4E-24 T 28-03-2018 IPR021235 Protein of unknown function DUF2637 SMD44_RS01710 8bb5e4f889456d18489f04d513171f1c 144 Pfam PF07291 Methylamine utilisation protein MauE 2 122 3.6E-7 T 28-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 SMD44_RS33040 4c24be27641b5d57896eeaa7b520b375 485 Pfam PF00860 Permease family 45 437 1.1E-34 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS11950 773f13bb27d8b181bda673f183f957f6 407 Pfam PF07690 Major Facilitator Superfamily 8 339 6.7E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS11950 773f13bb27d8b181bda673f183f957f6 407 Gene3D G3DSA:1.20.1250.20 3 186 1.1E-28 T 28-03-2018 SMD44_RS11950 773f13bb27d8b181bda673f183f957f6 407 Gene3D G3DSA:1.20.1250.20 193 384 4.1E-11 T 28-03-2018 SMD44_RS11950 773f13bb27d8b181bda673f183f957f6 407 SUPERFAMILY SSF103473 3 380 1.01E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS37560 5cb09ddbf1b9d4321d4c5c1f9f78a96e 367 Pfam PF06224 Winged helix DNA-binding domain 35 354 5.2E-67 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 SMD44_RS24315 74b65527efec5247f556f84e973f174b 352 Pfam PF10503 Esterase PHB depolymerase 85 208 6.2E-11 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SMD44_RS24315 74b65527efec5247f556f84e973f174b 352 Gene3D G3DSA:3.40.50.1820 51 312 2.3E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS24315 74b65527efec5247f556f84e973f174b 352 SUPERFAMILY SSF53474 68 306 5.01E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS25435 42034c3c4309c0bf971d375735dd4597 299 SUPERFAMILY SSF89392 140 278 2.2E-10 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD44_RS25435 42034c3c4309c0bf971d375735dd4597 299 Gene3D G3DSA:3.40.190.10 1 296 1.4E-5 T 28-03-2018 SMD44_RS18155 869de9e0ab907c9bf547a78c775164df 462 Gene3D G3DSA:1.10.260.40 2 90 5.0E-4 T 28-03-2018 SMD44_RS18155 869de9e0ab907c9bf547a78c775164df 462 Gene3D G3DSA:1.25.40.10 165 452 7.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS18155 869de9e0ab907c9bf547a78c775164df 462 SUPERFAMILY SSF48452 353 422 8.85E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS18155 869de9e0ab907c9bf547a78c775164df 462 SUPERFAMILY SSF48452 223 255 8.85E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS06550 0b88378697e9becbac870256a09197fe 142 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 139 7.6E-21 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS06550 0b88378697e9becbac870256a09197fe 142 Gene3D G3DSA:3.30.530.20 1 141 7.1E-24 T 28-03-2018 IPR023393 START-like domain SMD44_RS06550 0b88378697e9becbac870256a09197fe 142 SUPERFAMILY SSF55961 1 141 2.84E-22 T 28-03-2018 SMD44_RS17925 83afa802e9cb14a008c95581d6edfdb2 270 Gene3D G3DSA:3.90.226.10 15 266 2.4E-50 T 28-03-2018 SMD44_RS17925 83afa802e9cb14a008c95581d6edfdb2 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 243 4.0E-41 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD44_RS17925 83afa802e9cb14a008c95581d6edfdb2 270 SUPERFAMILY SSF52096 17 253 1.47E-52 T 28-03-2018 IPR029045 ClpP/crotonase-like domain SMD44_RS16185 3457fa9c1c1105b7d29b243f139b79d8 748 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 358 720 5.2E-126 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 SMD44_RS16185 3457fa9c1c1105b7d29b243f139b79d8 748 Gene3D G3DSA:3.90.550.10 1 257 3.0E-4 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS16185 3457fa9c1c1105b7d29b243f139b79d8 748 SUPERFAMILY SSF53756 518 719 7.43E-11 T 28-03-2018 SMD44_RS40200 f50a3c34bc252e7620782d49ebd8bc46 241 Pfam PF07730 Histidine kinase 192 219 4.3E-8 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS30130 eb368e80d8adb5f5c0c60729178cbdde 178 SUPERFAMILY SSF47598 113 167 6.23E-10 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMD44_RS30130 eb368e80d8adb5f5c0c60729178cbdde 178 Gene3D G3DSA:1.10.1220.10 104 156 2.2E-11 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS30130 eb368e80d8adb5f5c0c60729178cbdde 178 Pfam PF05534 HicB family 107 147 4.1E-5 T 28-03-2018 IPR008651 Uncharacterised protein family HicB SMD44_RS20355 2015e6420c4d634ba0146864c9312c55 220 Gene3D G3DSA:2.160.10.10 43 217 7.2E-36 T 28-03-2018 SMD44_RS20355 2015e6420c4d634ba0146864c9312c55 220 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 124 157 4.0E-7 T 28-03-2018 IPR001451 Hexapeptide repeat SMD44_RS20355 2015e6420c4d634ba0146864c9312c55 220 SUPERFAMILY SSF51161 68 215 9.56E-40 T 28-03-2018 IPR011004 Trimeric LpxA-like SMD44_RS13590 ab37f61720e9562a7408da4a9406cd93 74 Pfam PF04149 Domain of unknown function (DUF397) 9 65 1.3E-19 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS13790 5a6c745d7e6564e9cada6915907d1a16 371 Gene3D G3DSA:3.20.20.70 6 369 4.0E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13790 5a6c745d7e6564e9cada6915907d1a16 371 Pfam PF03060 Nitronate monooxygenase 5 357 1.8E-104 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMD44_RS13790 5a6c745d7e6564e9cada6915907d1a16 371 SUPERFAMILY SSF51412 113 362 3.21E-61 T 28-03-2018 SMD44_RS13790 5a6c745d7e6564e9cada6915907d1a16 371 SUPERFAMILY SSF51412 9 72 3.21E-61 T 28-03-2018 SMD44_RS24025 d2cc20867986aec0a6b652a40cc7d1bd 278 Gene3D G3DSA:3.40.50.150 30 252 7.8E-28 T 28-03-2018 SMD44_RS24025 d2cc20867986aec0a6b652a40cc7d1bd 278 SUPERFAMILY SSF53335 32 178 5.0E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS24025 d2cc20867986aec0a6b652a40cc7d1bd 278 Pfam PF08241 Methyltransferase domain 68 158 4.0E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS22165 3716d9dac3552b6ffcfd922e0980047b 131 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 6 122 1.0E-18 T 28-03-2018 IPR018727 Protein of unknown function DUF2267 SMD44_RS33345 0c548ccd4dfbf9bd1e7f0f6d3b4da589 125 Pfam PF13309 HTH domain 56 117 5.8E-20 T 28-03-2018 SMD44_RS33345 0c548ccd4dfbf9bd1e7f0f6d3b4da589 125 Gene3D G3DSA:1.10.10.60 65 125 1.2E-6 T 28-03-2018 SMD44_RS21385 067b3a57a5ecf02489d33c934ef227d1 286 Gene3D G3DSA:3.30.450.40 6 236 7.0E-14 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS21385 067b3a57a5ecf02489d33c934ef227d1 286 Gene3D G3DSA:1.10.10.10 237 275 1.7E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21385 067b3a57a5ecf02489d33c934ef227d1 286 SUPERFAMILY SSF55781 86 195 3.03E-13 T 28-03-2018 IPR029016 GAF domain-like SMD44_RS22715 7441432addb208a0849c810c43d04b02 205 Pfam PF16316 Domain of unknown function (DUF4956) 13 181 1.7E-48 T 28-03-2018 IPR032531 Protein of unknown function DUF4956 SMD44_RS11795 0b162d31c9114d049e30d876df96bac4 506 Pfam PF09362 Domain of unknown function (DUF1996) 261 485 2.1E-29 T 28-03-2018 IPR018535 Domain of unknown function DUF1996 SMD44_RS17920 f460c98ae1e4bcaeb52d4aa2d146b781 155 SUPERFAMILY SSF50249 11 145 1.71E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS17920 f460c98ae1e4bcaeb52d4aa2d146b781 155 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 26 64 1.3E-9 T 28-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMD44_RS17920 f460c98ae1e4bcaeb52d4aa2d146b781 155 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 65 139 6.4E-15 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMD44_RS17920 f460c98ae1e4bcaeb52d4aa2d146b781 155 Gene3D G3DSA:2.40.50.140 68 147 5.2E-12 T 28-03-2018 SMD44_RS07165 6f8aa12811f35882f052c63345a68bde 350 Gene3D G3DSA:3.40.50.1360 72 333 1.7E-38 T 28-03-2018 SMD44_RS07165 6f8aa12811f35882f052c63345a68bde 350 Gene3D G3DSA:1.10.10.60 23 71 1.3E-7 T 28-03-2018 SMD44_RS07165 6f8aa12811f35882f052c63345a68bde 350 Pfam PF04198 Putative sugar-binding domain 81 332 1.6E-66 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 SMD44_RS07165 6f8aa12811f35882f052c63345a68bde 350 SUPERFAMILY SSF100950 85 332 1.21E-53 T 28-03-2018 SMD44_RS22415 98dff8697a989a84455096a01c60e31b 366 Pfam PF04893 Yip1 domain 201 358 1.4E-12 T 28-03-2018 IPR006977 Yip1 domain GO:0016020 SMD44_RS19265 1e3a82259be3a90596c38f3a23e72e2a 85 Pfam PF11298 Protein of unknown function (DUF3099) 3 59 5.4E-7 T 28-03-2018 IPR021449 Protein of unknown function DUF3099 SMD44_RS02070 db2e2d0ee5377c5212af341d3e955aae 274 Gene3D G3DSA:3.20.20.70 50 252 6.4E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS02070 db2e2d0ee5377c5212af341d3e955aae 274 Pfam PF03537 Glycoside-hydrolase family GH114 49 251 1.1E-47 T 28-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain SMD44_RS02070 db2e2d0ee5377c5212af341d3e955aae 274 SUPERFAMILY SSF51445 49 247 1.09E-18 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS15290 001e23c4c310a31248e25c023d974581 444 Gene3D G3DSA:3.30.565.10 303 438 7.2E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15290 001e23c4c310a31248e25c023d974581 444 Pfam PF07730 Histidine kinase 240 306 7.2E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS15290 001e23c4c310a31248e25c023d974581 444 Pfam PF13796 Putative sensor 29 212 1.3E-32 T 28-03-2018 IPR025828 Putative sensor domain SMD44_RS15290 001e23c4c310a31248e25c023d974581 444 SUPERFAMILY SSF55874 341 432 1.81E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS05005 4d04aa7cb2b791e01450fdea716d875e 413 Gene3D G3DSA:1.20.1250.20 21 216 2.7E-18 T 28-03-2018 SMD44_RS05005 4d04aa7cb2b791e01450fdea716d875e 413 SUPERFAMILY SSF103473 14 402 1.57E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS05005 4d04aa7cb2b791e01450fdea716d875e 413 Gene3D G3DSA:1.20.1250.20 217 409 3.8E-21 T 28-03-2018 SMD44_RS05005 4d04aa7cb2b791e01450fdea716d875e 413 Pfam PF07690 Major Facilitator Superfamily 47 367 3.6E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS34125 a3ed6c8c564dd7fbb239909214ebff8d 164 Pfam PF00293 NUDIX domain 19 133 6.5E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS34125 a3ed6c8c564dd7fbb239909214ebff8d 164 Gene3D G3DSA:3.90.79.10 11 150 2.7E-22 T 28-03-2018 SMD44_RS34125 a3ed6c8c564dd7fbb239909214ebff8d 164 SUPERFAMILY SSF55811 14 147 3.93E-23 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS00635 be864f46e5b4f9b5aef44a5322ebf7b2 750 SUPERFAMILY SSF82866 135 346 4.97E-25 T 28-03-2018 SMD44_RS00635 be864f46e5b4f9b5aef44a5322ebf7b2 750 SUPERFAMILY SSF82866 487 718 7.59E-28 T 28-03-2018 SMD44_RS00635 be864f46e5b4f9b5aef44a5322ebf7b2 750 Pfam PF03176 MMPL family 46 391 9.7E-53 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS00635 be864f46e5b4f9b5aef44a5322ebf7b2 750 Pfam PF03176 MMPL family 485 718 3.0E-32 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS00635 be864f46e5b4f9b5aef44a5322ebf7b2 750 Gene3D G3DSA:1.20.1640.10 488 715 1.3E-30 T 28-03-2018 SMD44_RS00635 be864f46e5b4f9b5aef44a5322ebf7b2 750 Gene3D G3DSA:1.20.1640.10 132 347 3.1E-25 T 28-03-2018 SMD44_RS35980 f8775769b738f829c7f98ec3be272fd1 347 Gene3D G3DSA:3.40.190.10 41 152 8.3E-18 T 28-03-2018 SMD44_RS35980 f8775769b738f829c7f98ec3be272fd1 347 Gene3D G3DSA:3.40.190.10 153 346 2.4E-23 T 28-03-2018 SMD44_RS35980 f8775769b738f829c7f98ec3be272fd1 347 SUPERFAMILY SSF53850 42 274 3.3E-34 T 28-03-2018 SMD44_RS35980 f8775769b738f829c7f98ec3be272fd1 347 Pfam PF09084 NMT1/THI5 like 55 270 5.5E-39 T 28-03-2018 IPR015168 SsuA/THI5-like SMD44_RS25800 d1a840fb0279ff2af847d846c26b033d 105 Pfam PF02467 Transcription factor WhiB 17 87 5.7E-25 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS25800 d1a840fb0279ff2af847d846c26b033d 105 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 95 19.571 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS05010 0806e24af91529b1d8cc8b813225cf1d 143 Pfam PF13160 Protein of unknown function (DUF3995) 14 132 3.1E-21 T 28-03-2018 IPR025058 Protein of unknown function DUF3995 SMD44_RS11000 94a2c786458634c8022eb7ba1875c56d 215 Hamap MF_01197 Cell division protein SepF [sepF]. 2 206 22.459 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 SMD44_RS11000 94a2c786458634c8022eb7ba1875c56d 215 Pfam PF04472 Cell division protein SepF 127 198 3.6E-27 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SMD44_RS10165 ee9c7527d0b0452961b4e92bbe5da826 308 Gene3D G3DSA:1.10.260.40 14 96 3.4E-4 T 28-03-2018 SMD44_RS08515 51195e1303e857ee8d00081b2c6ed11f 407 Gene3D G3DSA:1.20.140.10 241 407 1.0E-43 T 28-03-2018 SMD44_RS08515 51195e1303e857ee8d00081b2c6ed11f 407 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 252 402 3.8E-34 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS08515 51195e1303e857ee8d00081b2c6ed11f 407 SUPERFAMILY SSF56645 2 265 2.75E-60 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS08515 51195e1303e857ee8d00081b2c6ed11f 407 Gene3D G3DSA:2.40.110.10 137 240 9.9E-33 T 28-03-2018 SMD44_RS08515 51195e1303e857ee8d00081b2c6ed11f 407 Gene3D G3DSA:1.10.540.10 1 136 2.4E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS08515 51195e1303e857ee8d00081b2c6ed11f 407 SUPERFAMILY SSF47203 250 406 2.26E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS08515 51195e1303e857ee8d00081b2c6ed11f 407 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 133 3.8E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS08515 51195e1303e857ee8d00081b2c6ed11f 407 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 238 1.2E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMD44_RS20475 5e2cd47b03e0442abeb9b656f9d66322 168 SUPERFAMILY SSF54427 50 148 6.08E-7 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS20475 5e2cd47b03e0442abeb9b656f9d66322 168 Gene3D G3DSA:3.10.450.50 73 167 0.0028 T 28-03-2018 SMD44_RS20475 5e2cd47b03e0442abeb9b656f9d66322 168 Gene3D G3DSA:3.10.450.50 32 72 0.0076 T 28-03-2018 SMD44_RS33705 73c61a89c1baf7948757866571f76326 158 Gene3D G3DSA:2.80.10.50 12 157 6.5E-7 T 28-03-2018 SMD44_RS12235 c4e68b8d5b1b6c518645225c957fcba2 176 Pfam PF02591 C4-type zinc ribbon domain 134 168 4.3E-13 T 28-03-2018 IPR003743 C4-type zinc ribbon domain SMD44_RS12235 c4e68b8d5b1b6c518645225c957fcba2 176 Gene3D G3DSA:1.20.120.330 2 149 1.8E-7 T 28-03-2018 SMD44_RS08715 08530eb762235be6ead6af9618244a98 270 Gene3D G3DSA:3.90.550.10 11 266 8.4E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS08715 08530eb762235be6ead6af9618244a98 270 Pfam PF00535 Glycosyl transferase family 2 32 150 2.0E-21 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS08715 08530eb762235be6ead6af9618244a98 270 SUPERFAMILY SSF53448 25 241 1.33E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS07495 b5fbb6ca6d2a7b54627b6818b32f8000 224 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD44_RS07495 b5fbb6ca6d2a7b54627b6818b32f8000 224 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 2.0E-9 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD44_RS05740 9c0aff95f1fea9f72c595a4007b2c10c 224 PIRSF PIRSF009467 1 224 4.6E-44 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMD44_RS05740 9c0aff95f1fea9f72c595a4007b2c10c 224 Pfam PF01730 UreF 34 174 9.3E-20 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMD44_RS05740 9c0aff95f1fea9f72c595a4007b2c10c 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 2 224 18.141 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMD44_RS17610 9983d88e1a551fafac1175204c8c4e85 441 SUPERFAMILY SSF53850 34 405 1.68E-15 T 28-03-2018 SMD44_RS17610 9983d88e1a551fafac1175204c8c4e85 441 Gene3D G3DSA:3.40.190.10 35 152 2.5E-6 T 28-03-2018 SMD44_RS17610 9983d88e1a551fafac1175204c8c4e85 441 Gene3D G3DSA:3.40.190.10 153 392 1.3E-6 T 28-03-2018 SMD44_RS09765 06590f8fe32be4d623a31ae7baa04b36 418 Gene3D G3DSA:3.30.565.10 266 418 4.9E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS09765 06590f8fe32be4d623a31ae7baa04b36 418 Pfam PF07730 Histidine kinase 188 252 1.1E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS09765 06590f8fe32be4d623a31ae7baa04b36 418 SUPERFAMILY SSF55874 309 384 1.59E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS37405 a773cdef7cd5e741e64d74269caae565 365 Gene3D G3DSA:3.50.50.60 1 340 1.2E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37405 a773cdef7cd5e741e64d74269caae565 365 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 3.4E-8 T 28-03-2018 SMD44_RS37405 a773cdef7cd5e741e64d74269caae565 365 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 3.4E-8 T 28-03-2018 SMD44_RS37405 a773cdef7cd5e741e64d74269caae565 365 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 303 3.4E-8 T 28-03-2018 SMD44_RS37405 a773cdef7cd5e741e64d74269caae565 365 Pfam PF01494 FAD binding domain 1 334 1.0E-29 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS37405 a773cdef7cd5e741e64d74269caae565 365 SUPERFAMILY SSF51905 1 165 2.65E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS37405 a773cdef7cd5e741e64d74269caae565 365 SUPERFAMILY SSF51905 259 341 2.65E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS21300 b2e9d8f89b352ae9dab9ed3b5aa47f11 493 Pfam PF04932 O-Antigen ligase 198 352 6.5E-19 T 28-03-2018 IPR007016 O-antigen ligase-related SMD44_RS03905 0384fc79b3e2c01d81d1ac88ac81e86e 242 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 71 242 6.8E-78 T 28-03-2018 IPR018655 Protein of unknown function DUF2086 SMD44_RS03905 0384fc79b3e2c01d81d1ac88ac81e86e 242 Gene3D G3DSA:2.60.120.620 20 242 1.5E-18 T 28-03-2018 SMD44_RS02500 d97f6bd6ed7ead2f833249f8871c47ef 486 Gene3D G3DSA:1.20.1250.20 277 486 2.5E-16 T 28-03-2018 SMD44_RS02500 d97f6bd6ed7ead2f833249f8871c47ef 486 Gene3D G3DSA:1.20.1250.20 20 217 1.8E-32 T 28-03-2018 SMD44_RS02500 d97f6bd6ed7ead2f833249f8871c47ef 486 Pfam PF07690 Major Facilitator Superfamily 34 433 2.0E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS02500 d97f6bd6ed7ead2f833249f8871c47ef 486 SUPERFAMILY SSF103473 18 211 2.75E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS02500 d97f6bd6ed7ead2f833249f8871c47ef 486 SUPERFAMILY SSF103473 266 479 2.75E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS35735 aa832c48bc73277ff09716a52a5e28e5 61 Gene3D G3DSA:1.20.5.340 2 59 4.7E-4 T 28-03-2018 SMD44_RS11350 c95eabcfc2f1bafc4c8cdbfa106e70f7 471 Pfam PF00939 Sodium:sulfate symporter transmembrane region 14 466 1.7E-25 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 SMD44_RS23795 13a3d09abc3d0e2e375cc6802f560323 400 Gene3D G3DSA:3.30.565.10 217 397 6.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS23795 13a3d09abc3d0e2e375cc6802f560323 400 Pfam PF07730 Histidine kinase 189 254 3.8E-21 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS23795 13a3d09abc3d0e2e375cc6802f560323 400 SUPERFAMILY SSF55874 272 396 1.16E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS34045 e5407e5f42e73857b6c078977a0cd749 246 Pfam PF14016 Protein of unknown function (DUF4232) 110 236 3.5E-22 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 SMD44_RS19270 525e85822d19354d4b77bc3de00912e1 95 SUPERFAMILY SSF49478 20 78 2.2E-5 T 28-03-2018 SMD44_RS19270 525e85822d19354d4b77bc3de00912e1 95 Pfam PF07210 Protein of unknown function (DUF1416) 2 95 3.9E-36 T 28-03-2018 IPR010814 Protein of unknown function DUF1416 SMD44_RS19270 525e85822d19354d4b77bc3de00912e1 95 Gene3D G3DSA:2.60.40.1120 13 95 1.4E-6 T 28-03-2018 SMD44_RS29165 0e65f73b433fd85fe1f73e42c9f307cd 69 Pfam PF04149 Domain of unknown function (DUF397) 7 62 1.2E-18 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS39530 eba391dd3af2d3efa7d89673a7cfbdac 300 SUPERFAMILY SSF161098 97 282 4.32E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS39530 eba391dd3af2d3efa7d89673a7cfbdac 300 Gene3D G3DSA:1.10.3720.10 40 295 2.3E-28 T 28-03-2018 SMD44_RS39530 eba391dd3af2d3efa7d89673a7cfbdac 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 288 9.0E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS36950 2010fbb79cbfabd23bc3bae98b5a14f6 157 Pfam PF03703 Bacterial PH domain 67 143 2.4E-13 T 28-03-2018 IPR005182 Domain of unknown function DUF304 SMD44_RS40550 d8f7bb422ff9fe6b09a2876d5b30693b 348 SUPERFAMILY SSF52242 86 203 9.73E-19 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS40550 d8f7bb422ff9fe6b09a2876d5b30693b 348 Gene3D G3DSA:3.40.50.280 80 207 1.8E-24 T 28-03-2018 SMD44_RS40550 d8f7bb422ff9fe6b09a2876d5b30693b 348 Pfam PF02310 B12 binding domain 92 200 2.5E-15 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD44_RS40550 d8f7bb422ff9fe6b09a2876d5b30693b 348 Gene3D G3DSA:1.10.490.20 223 337 1.8E-16 T 28-03-2018 SMD44_RS18580 b43de5f1ced13bac387204d5f32dbcab 164 Gene3D G3DSA:3.40.50.1700 87 162 0.0016 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMD44_RS36245 730406870c224d7f5dddc48b2760a3d4 420 SUPERFAMILY SSF55469 2 111 3.27E-9 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS36245 730406870c224d7f5dddc48b2760a3d4 420 SUPERFAMILY SSF55469 319 413 4.59E-6 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS36245 730406870c224d7f5dddc48b2760a3d4 420 SUPERFAMILY SSF55469 182 241 4.59E-6 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS36245 730406870c224d7f5dddc48b2760a3d4 420 Gene3D G3DSA:3.40.109.10 175 419 2.0E-17 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS36245 730406870c224d7f5dddc48b2760a3d4 420 Gene3D G3DSA:3.40.109.10 1 152 9.7E-12 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD44_RS09810 b8fdc0beb8116a01bbd9ace9e3f2fd22 405 Pfam PF07690 Major Facilitator Superfamily 20 228 3.8E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS09810 b8fdc0beb8116a01bbd9ace9e3f2fd22 405 Gene3D G3DSA:1.20.1250.20 2 203 2.1E-15 T 28-03-2018 SMD44_RS09810 b8fdc0beb8116a01bbd9ace9e3f2fd22 405 SUPERFAMILY SSF103473 11 392 7.72E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS09810 b8fdc0beb8116a01bbd9ace9e3f2fd22 405 Gene3D G3DSA:1.20.1250.20 207 393 2.5E-16 T 28-03-2018 SMD44_RS21680 07da92b11c0e12218993b68b2a30f39f 261 SUPERFAMILY SSF47240 32 255 5.41E-65 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS21680 07da92b11c0e12218993b68b2a30f39f 261 Gene3D G3DSA:1.20.1260.10 14 261 8.7E-66 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS21680 07da92b11c0e12218993b68b2a30f39f 261 Pfam PF05138 Phenylacetic acid catabolic protein 20 261 1.1E-75 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 SMD44_RS21680 07da92b11c0e12218993b68b2a30f39f 261 PIRSF PIRSF037834 18 261 1.5E-91 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 SMD44_RS21680 07da92b11c0e12218993b68b2a30f39f 261 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 35 261 4.4E-78 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 SMD44_RS28365 1b67ed9f9a818489ffad7e53cc55130f 276 SUPERFAMILY SSF161098 2 276 8.41E-73 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS28365 1b67ed9f9a818489ffad7e53cc55130f 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 264 1.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS28365 1b67ed9f9a818489ffad7e53cc55130f 276 Gene3D G3DSA:1.10.3720.10 1 263 1.1E-46 T 28-03-2018 SMD44_RS10900 bcc4b5ef87ed10794ff7704f87c1e00c 404 Gene3D G3DSA:3.40.50.1010 1 176 1.1E-26 T 28-03-2018 IPR029060 PIN domain-like SMD44_RS10900 bcc4b5ef87ed10794ff7704f87c1e00c 404 Pfam PF01936 NYN domain 30 166 2.2E-11 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type SMD44_RS15550 2ab447e446f8ed8c88a44ed7c66b0813 444 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 231 425 1.1E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS15550 2ab447e446f8ed8c88a44ed7c66b0813 444 Gene3D G3DSA:3.40.50.1110 220 434 3.6E-28 T 28-03-2018 SMD44_RS15550 2ab447e446f8ed8c88a44ed7c66b0813 444 SUPERFAMILY SSF52266 224 431 3.05E-43 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS06830 3bf77422d9087b0e56a86fa8fb568442 295 SUPERFAMILY SSF50891 177 286 3.15E-14 T 28-03-2018 IPR029000 Cyclophilin-like domain SMD44_RS06830 3bf77422d9087b0e56a86fa8fb568442 295 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 28 284 3.7E-83 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B SMD44_RS06830 3bf77422d9087b0e56a86fa8fb568442 295 SMART SM00797 27 293 5.7E-93 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B SMD44_RS06830 3bf77422d9087b0e56a86fa8fb568442 295 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 7 285 1.5E-77 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B SMD44_RS08265 1930d2a845e779cd759bb1ae04d60f42 206 Pfam PF00174 Oxidoreductase molybdopterin binding domain 42 186 7.1E-34 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS08265 1930d2a845e779cd759bb1ae04d60f42 206 Gene3D G3DSA:3.90.420.10 12 206 1.1E-52 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS08265 1930d2a845e779cd759bb1ae04d60f42 206 SUPERFAMILY SSF56524 22 204 8.63E-59 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD44_RS19710 36acd154c8ff46f50514c3cab5feb562 157 Gene3D G3DSA:3.40.630.30 1 155 7.1E-28 T 28-03-2018 SMD44_RS19710 36acd154c8ff46f50514c3cab5feb562 157 Pfam PF13420 Acetyltransferase (GNAT) domain 5 146 2.6E-12 T 28-03-2018 SMD44_RS19710 36acd154c8ff46f50514c3cab5feb562 157 SUPERFAMILY SSF55729 1 151 7.98E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS19550 ab4fcf30b04430958c46a8f671459752 424 Gene3D G3DSA:1.20.1250.20 7 188 1.4E-24 T 28-03-2018 SMD44_RS19550 ab4fcf30b04430958c46a8f671459752 424 SUPERFAMILY SSF103473 9 386 6.93E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS19550 ab4fcf30b04430958c46a8f671459752 424 Pfam PF07690 Major Facilitator Superfamily 11 242 4.8E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS19550 ab4fcf30b04430958c46a8f671459752 424 Gene3D G3DSA:1.20.1250.20 197 408 4.4E-21 T 28-03-2018 SMD44_RS05200 987e30df93b4330c4d5e6d605a058844 128 SUPERFAMILY SSF50475 5 125 1.63E-14 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS05200 987e30df93b4330c4d5e6d605a058844 128 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 3 127 5.7E-47 T 28-03-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative SMD44_RS05200 987e30df93b4330c4d5e6d605a058844 128 Gene3D G3DSA:2.30.110.10 2 122 7.3E-15 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS41095 02875ac61fd02abba3f8c4e1fa8eacd9 136 Gene3D G3DSA:2.60.40.10 28 119 3.3E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS00905 fdf43a09e01df11092bda5dbf4039878 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 2.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00905 fdf43a09e01df11092bda5dbf4039878 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 2.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00905 fdf43a09e01df11092bda5dbf4039878 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 2.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00905 fdf43a09e01df11092bda5dbf4039878 219 Gene3D G3DSA:1.10.10.10 4 219 4.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS00905 fdf43a09e01df11092bda5dbf4039878 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 1.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS00905 fdf43a09e01df11092bda5dbf4039878 219 SUPERFAMILY SSF46894 149 219 3.13E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS00905 fdf43a09e01df11092bda5dbf4039878 219 SMART SM00421 156 213 1.8E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS20205 e48b97b038520a23559f960f718b9375 183 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 2 181 8.9E-25 T 28-03-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative SMD44_RS17425 24bd63484b8deb848976709f6f78ee65 364 Pfam PF14027 Protein of unknown function (DUF4243) 41 340 3.1E-27 T 28-03-2018 IPR025337 Domain of unknown function DUF4243 SMD44_RS39645 9b9922d5597ebb4f168277295cd01949 386 Gene3D G3DSA:3.40.50.980 47 207 3.9E-11 T 28-03-2018 SMD44_RS39645 9b9922d5597ebb4f168277295cd01949 386 SUPERFAMILY SSF56801 23 373 7.06E-31 T 28-03-2018 SMD44_RS39645 9b9922d5597ebb4f168277295cd01949 386 Gene3D G3DSA:3.30.300.30 283 383 9.3E-12 T 28-03-2018 SMD44_RS13060 1810681f47ef5a23f417388996ebd579 273 Pfam PF04016 Putative heavy-metal chelation 136 243 7.9E-13 T 28-03-2018 IPR007161 Putative heavy-metal chelation domain SMD44_RS13060 1810681f47ef5a23f417388996ebd579 273 Gene3D G3DSA:3.20.20.70 73 271 1.2E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13060 1810681f47ef5a23f417388996ebd579 273 SUPERFAMILY SSF159713 47 244 1.7E-21 T 28-03-2018 SMD44_RS30530 046e0bad073530e461a7b6ce70ef9f40 130 SUPERFAMILY SSF52980 17 114 3.33E-18 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS30530 046e0bad073530e461a7b6ce70ef9f40 130 Pfam PF02021 Uncharacterised protein family UPF0102 21 113 2.5E-25 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 SMD44_RS30530 046e0bad073530e461a7b6ce70ef9f40 130 Hamap MF_00048 UPF0102 protein YraN [yraN]. 14 126 20.606 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 SMD44_RS30530 046e0bad073530e461a7b6ce70ef9f40 130 Gene3D G3DSA:3.40.1350.10 20 129 1.6E-33 T 28-03-2018 SMD44_RS12905 2099ce7d2511a84b6dcc4fba08a1ab50 291 SUPERFAMILY SSF56059 94 273 1.14E-11 T 28-03-2018 SMD44_RS12905 2099ce7d2511a84b6dcc4fba08a1ab50 291 Gene3D G3DSA:3.30.470.20 150 277 8.7E-8 T 28-03-2018 SMD44_RS11325 33705e31e8e28ae685ab417d600f028c 243 SUPERFAMILY SSF144091 18 224 2.35E-37 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD44_RS11325 33705e31e8e28ae685ab417d600f028c 243 Gene3D G3DSA:1.20.1540.10 17 225 1.6E-41 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD44_RS11325 33705e31e8e28ae685ab417d600f028c 243 Pfam PF01694 Rhomboid family 73 224 3.4E-38 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD44_RS43400 086aa515e6104a60974786530d88725e 866 SUPERFAMILY SSF52540 417 789 1.73E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS43400 086aa515e6104a60974786530d88725e 866 Gene3D G3DSA:3.40.50.300 459 807 5.1E-11 T 28-03-2018 SMD44_RS43400 086aa515e6104a60974786530d88725e 866 Pfam PF12846 AAA-like domain 455 835 2.5E-69 T 28-03-2018 SMD44_RS43400 086aa515e6104a60974786530d88725e 866 PIRSF PIRSF015040 1 856 9.7E-160 T 28-03-2018 IPR016628 ATPase, SAG2001, predicted SMD44_RS32410 5afeea4389e29f4c531d770a564ecd48 127 Pfam PF12647 RNHCP domain 19 104 5.9E-37 T 28-03-2018 IPR024439 RNHCP domain SMD44_RS31795 3ad4bec377f42a3c4093c495ca9359f4 71 Pfam PF03621 MbtH-like protein 3 53 5.6E-29 T 28-03-2018 IPR005153 MbtH-like protein SMD44_RS31795 3ad4bec377f42a3c4093c495ca9359f4 71 SUPERFAMILY SSF160582 3 69 2.88E-31 T 28-03-2018 SMD44_RS31795 3ad4bec377f42a3c4093c495ca9359f4 71 SMART SM00923 4 54 1.1E-33 T 28-03-2018 IPR005153 MbtH-like protein SMD44_RS31795 3ad4bec377f42a3c4093c495ca9359f4 71 Gene3D G3DSA:3.90.820.10 3 69 3.7E-36 T 28-03-2018 SMD44_RS32115 53406c9e3079750b2b4ff6c76979b7f7 425 Pfam PF07730 Histidine kinase 188 253 6.4E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS32115 53406c9e3079750b2b4ff6c76979b7f7 425 SUPERFAMILY SSF55874 310 410 4.52E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS32115 53406c9e3079750b2b4ff6c76979b7f7 425 Gene3D G3DSA:3.30.565.10 288 422 1.2E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS01750 debe75ecc3b8243e7158636597a5f94a 344 Pfam PF14716 Helix-hairpin-helix domain 4 69 6.1E-14 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain SMD44_RS01750 debe75ecc3b8243e7158636597a5f94a 344 SUPERFAMILY SSF89550 101 326 2.49E-45 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD44_RS01750 debe75ecc3b8243e7158636597a5f94a 344 Gene3D G3DSA:1.10.150.110 2 83 1.2E-12 T 28-03-2018 SMD44_RS01750 debe75ecc3b8243e7158636597a5f94a 344 SUPERFAMILY SSF47802 3 81 1.83E-10 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain SMD44_RS01750 debe75ecc3b8243e7158636597a5f94a 344 SMART SM00481 102 181 5.0E-16 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMD44_RS01750 debe75ecc3b8243e7158636597a5f94a 344 PIRSF PIRSF036978 1 338 1.6E-180 T 28-03-2018 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 SMD44_RS01750 debe75ecc3b8243e7158636597a5f94a 344 Gene3D G3DSA:3.20.20.140 103 328 4.6E-47 T 28-03-2018 SMD44_RS12745 b6cba744d8b3ba0633cb0855b8211680 165 Gene3D G3DSA:3.40.630.30 3 161 6.9E-20 T 28-03-2018 SMD44_RS12745 b6cba744d8b3ba0633cb0855b8211680 165 Pfam PF00583 Acetyltransferase (GNAT) family 41 150 5.0E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS12745 b6cba744d8b3ba0633cb0855b8211680 165 SUPERFAMILY SSF55729 4 159 4.97E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS38935 7ce67893036da731bdc8e148930f94e6 242 Pfam PF11303 Protein of unknown function (DUF3105) 111 233 1.5E-41 T 28-03-2018 IPR021454 Protein of unknown function DUF3105 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 164 2.4E-22 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 1.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 Gene3D G3DSA:1.10.10.60 7 40 9.4E-15 T 28-03-2018 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 Gene3D G3DSA:1.10.260.40 41 72 1.1E-6 T 28-03-2018 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 4.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 PRINTS PR00400 Tetracycline repressor protein signature 77 96 2.8E-17 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 PRINTS PR00400 Tetracycline repressor protein signature 133 152 2.8E-17 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 PRINTS PR00400 Tetracycline repressor protein signature 97 120 2.8E-17 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 PRINTS PR00400 Tetracycline repressor protein signature 23 46 2.8E-17 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 SUPERFAMILY SSF46689 5 69 1.35E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 Gene3D G3DSA:1.10.357.10 73 235 4.7E-17 T 28-03-2018 SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 SUPERFAMILY SSF48498 73 161 3.89E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS26655 8423ca71f22f081095f3df31fc3d227b 242 SUPERFAMILY SSF48498 193 233 3.89E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS11065 ececa4a5315dc650ff3d9a963b8c9701 206 Pfam PF04977 Septum formation initiator 56 109 3.9E-8 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SMD44_RS13750 9f670cefc6cc6f4b5e5677915764f8eb 384 SUPERFAMILY SSF53613 38 337 1.87E-50 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS13750 9f670cefc6cc6f4b5e5677915764f8eb 384 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 281 294 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD44_RS13750 9f670cefc6cc6f4b5e5677915764f8eb 384 Pfam PF00294 pfkB family carbohydrate kinase 67 328 1.2E-32 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS13750 9f670cefc6cc6f4b5e5677915764f8eb 384 Gene3D G3DSA:3.40.1190.20 38 344 1.7E-55 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS31845 7ea82fdc86856936117f9b6bf4de071c 424 Gene3D G3DSA:1.20.91.10 242 328 3.7E-19 T 28-03-2018 SMD44_RS31845 7ea82fdc86856936117f9b6bf4de071c 424 Pfam PF00999 Sodium/hydrogen exchanger family 14 393 1.4E-46 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD44_RS34455 edbe8f5c18d23d7e56b43a5ed8d8c727 210 Pfam PF09335 SNARE associated Golgi protein 40 168 2.2E-12 T 28-03-2018 IPR032816 SNARE associated Golgi protein SMD44_RS19040 3296e5c850f320e1428d0d981232b8d8 374 SUPERFAMILY SSF89372 137 371 4.25E-20 T 28-03-2018 SMD44_RS19040 3296e5c850f320e1428d0d981232b8d8 374 SUPERFAMILY SSF89372 5 135 1.03E-9 T 28-03-2018 SMD44_RS19040 3296e5c850f320e1428d0d981232b8d8 374 Gene3D G3DSA:2.120.10.70 180 373 8.0E-18 T 28-03-2018 SMD44_RS19040 3296e5c850f320e1428d0d981232b8d8 374 Gene3D G3DSA:2.120.10.70 2 179 1.5E-17 T 28-03-2018 SMD44_RS01410 e2916d9b314261e5794a8e33fec909c6 200 SUPERFAMILY SSF55729 7 174 1.25E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS01410 e2916d9b314261e5794a8e33fec909c6 200 Pfam PF13302 Acetyltransferase (GNAT) domain 14 150 3.4E-22 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS01410 e2916d9b314261e5794a8e33fec909c6 200 Gene3D G3DSA:3.40.630.30 2 181 6.1E-27 T 28-03-2018 SMD44_RS08805 4a11be3996386b85545bbbb8baefa2d0 161 Pfam PF13599 Pentapeptide repeats (9 copies) 46 117 3.8E-11 T 28-03-2018 IPR001646 Pentapeptide repeat SMD44_RS08805 4a11be3996386b85545bbbb8baefa2d0 161 SUPERFAMILY SSF141571 9 149 2.88E-25 T 28-03-2018 SMD44_RS08805 4a11be3996386b85545bbbb8baefa2d0 161 Gene3D G3DSA:2.160.10.20 3 121 4.6E-20 T 28-03-2018 SMD44_RS37565 7d646492cab72329dcf3f26d10475ca5 146 SUPERFAMILY SSF54593 4 139 9.13E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS37565 7d646492cab72329dcf3f26d10475ca5 146 Gene3D G3DSA:3.10.180.10 1 146 3.5E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS16410 a777e1933e39f7f6ac779efc06addfb5 141 Pfam PF12005 Protein of unknown function (DUF3499) 20 137 3.8E-47 T 28-03-2018 IPR021888 Protein of unknown function DUF3499 SMD44_RS24375 c2dd83d9f63c0b06191fec7280ac4de2 379 Pfam PF01578 Cytochrome C assembly protein 167 371 1.1E-42 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 SMD44_RS24375 c2dd83d9f63c0b06191fec7280ac4de2 379 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 136 377 4.7E-76 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 SMD44_RS36000 831dda43e3d2c73631c878e85b05fe99 298 Gene3D G3DSA:3.20.20.150 49 297 2.3E-32 T 28-03-2018 SMD44_RS36000 831dda43e3d2c73631c878e85b05fe99 298 Pfam PF01261 Xylose isomerase-like TIM barrel 74 254 5.4E-11 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS36000 831dda43e3d2c73631c878e85b05fe99 298 SUPERFAMILY SSF51658 55 296 3.15E-30 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS01475 ce7e15f2ad3e62019fe8ecb99b2edcc6 331 Pfam PF01032 FecCD transport family 23 326 2.7E-70 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS01475 ce7e15f2ad3e62019fe8ecb99b2edcc6 331 SUPERFAMILY SSF81345 8 326 4.84E-64 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS01475 ce7e15f2ad3e62019fe8ecb99b2edcc6 331 Gene3D G3DSA:1.10.3470.10 7 331 1.6E-51 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS36425 4dd2ff43e996711fae95a0fd04e532ae 337 Gene3D G3DSA:1.20.1260.10 166 299 2.8E-6 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS36425 4dd2ff43e996711fae95a0fd04e532ae 337 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 25 314 2.0E-49 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF SMD44_RS14705 3977fb7171ba3ff5a506d2370bb3c9ed 479 Pfam PF13520 Amino acid permease 37 433 2.5E-34 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS14705 3977fb7171ba3ff5a506d2370bb3c9ed 479 PIRSF PIRSF006060 18 476 1.1E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS22970 df01749aab783bf015827395023f5847 242 Pfam PF01965 DJ-1/PfpI family 47 214 6.4E-18 T 28-03-2018 IPR002818 DJ-1/PfpI SMD44_RS22970 df01749aab783bf015827395023f5847 242 SUPERFAMILY SSF52317 45 233 4.42E-33 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS22970 df01749aab783bf015827395023f5847 242 Gene3D G3DSA:3.40.50.880 38 242 5.7E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS28135 f2b0b91e39734053dee51849ac8071e3 197 Pfam PF01863 Protein of unknown function DUF45 105 179 5.5E-23 T 28-03-2018 IPR002725 Protein of unknown function DUF45 SMD44_RS24000 7ad0b4bc4af9f7ea3ef6b1e7b35ca4d4 208 Gene3D G3DSA:1.10.10.60 3 76 2.2E-21 T 28-03-2018 SMD44_RS24000 7ad0b4bc4af9f7ea3ef6b1e7b35ca4d4 208 SUPERFAMILY SSF46689 18 95 3.18E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS24000 7ad0b4bc4af9f7ea3ef6b1e7b35ca4d4 208 Gene3D G3DSA:1.10.357.10 79 208 2.4E-37 T 28-03-2018 SMD44_RS24000 7ad0b4bc4af9f7ea3ef6b1e7b35ca4d4 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 3.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS24000 7ad0b4bc4af9f7ea3ef6b1e7b35ca4d4 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 3.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS24000 7ad0b4bc4af9f7ea3ef6b1e7b35ca4d4 208 SUPERFAMILY SSF48498 97 208 5.04E-35 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS24000 7ad0b4bc4af9f7ea3ef6b1e7b35ca4d4 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 1.4E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS31885 635eb9d7fd9c81f93102b99e52f6d26d 408 Gene3D G3DSA:1.50.10.100 38 386 3.6E-62 T 28-03-2018 SMD44_RS31885 635eb9d7fd9c81f93102b99e52f6d26d 408 SUPERFAMILY SSF48230 289 348 2.56E-44 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMD44_RS31885 635eb9d7fd9c81f93102b99e52f6d26d 408 SUPERFAMILY SSF48230 58 259 2.56E-44 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMD44_RS31885 635eb9d7fd9c81f93102b99e52f6d26d 408 Pfam PF05426 Alginate lyase 116 338 1.4E-13 T 28-03-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 SMD44_RS29420 83df3090f151bb9bd6453a5a69d757c5 391 Gene3D G3DSA:3.40.710.10 35 391 1.2E-73 T 28-03-2018 SMD44_RS29420 83df3090f151bb9bd6453a5a69d757c5 391 SUPERFAMILY SSF56601 51 372 6.63E-74 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS29420 83df3090f151bb9bd6453a5a69d757c5 391 Pfam PF00144 Beta-lactamase 63 373 1.7E-58 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS25265 ed0fa0111583d987c6bfc31f92844166 208 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 53 162 7.2E-24 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25265 ed0fa0111583d987c6bfc31f92844166 208 Gene3D G3DSA:3.40.50.700 23 186 1.1E-42 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25265 ed0fa0111583d987c6bfc31f92844166 208 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 167 40.271 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25265 ed0fa0111583d987c6bfc31f92844166 208 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 32 168 3.0E-66 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25265 ed0fa0111583d987c6bfc31f92844166 208 SUPERFAMILY SSF56770 31 172 2.75E-61 T 28-03-2018 SMD44_RS06790 3189ae33e02e7db94776bfb757273c67 1598 Gene3D G3DSA:3.40.50.300 58 619 0.0044 T 28-03-2018 SMD44_RS06790 3189ae33e02e7db94776bfb757273c67 1598 Gene3D G3DSA:1.20.1600.10 1050 1368 6.4E-4 T 28-03-2018 SMD44_RS00935 dc2718ceb7239a50b563d82e71f3a854 137 SMART SM00900 61 134 6.6E-9 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SMD44_RS00935 dc2718ceb7239a50b563d82e71f3a854 137 Pfam PF04205 FMN-binding domain 63 131 1.3E-11 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SMD44_RS07060 25d47269b78ab90ad5a6c66bfa0f26a1 471 Pfam PF00860 Permease family 34 405 8.1E-71 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS15505 3e53cd1612390cd98a460602d589afa2 213 Gene3D G3DSA:3.30.565.10 13 140 3.9E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15505 3e53cd1612390cd98a460602d589afa2 213 Pfam PF13581 Histidine kinase-like ATPase domain 21 117 3.8E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS24245 73d780be73c1d3438f3f5cb17be11519 408 Gene3D G3DSA:1.25.40.10 240 406 0.026 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS24245 73d780be73c1d3438f3f5cb17be11519 408 Gene3D G3DSA:1.10.150.200 140 232 4.8E-4 T 28-03-2018 SMD44_RS06530 1a50e0ea236e045e7efb2bb09133ee0a 376 SUPERFAMILY SSF103481 272 348 1.96E-10 T 28-03-2018 SMD44_RS06530 1a50e0ea236e045e7efb2bb09133ee0a 376 Pfam PF00892 EamA-like transporter family 201 346 2.6E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS06530 1a50e0ea236e045e7efb2bb09133ee0a 376 Pfam PF00892 EamA-like transporter family 59 189 3.9E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS06530 1a50e0ea236e045e7efb2bb09133ee0a 376 SUPERFAMILY SSF103481 94 190 2.75E-10 T 28-03-2018 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 SMART SM00841 130 185 3.1E-31 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 6.2E-26 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 3.2E-75 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 5.8E-25 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 SUPERFAMILY SSF50104 2 64 9.63E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 SMART SM01185 68 122 7.9E-27 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 Gene3D G3DSA:2.30.30.30 2 62 8.1E-26 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 Gene3D G3DSA:2.40.50.140 130 185 1.2E-26 T 28-03-2018 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 SUPERFAMILY SSF50249 130 186 1.51E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 SUPERFAMILY SSF50249 66 130 1.2E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 51.12 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 PIRSF PIRSF005901 1 187 2.6E-66 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 9.1E-22 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SMD44_RS07295 9dc415143f41242097023095d8f5837e 188 Gene3D G3DSA:2.40.50.140 66 127 3.1E-23 T 28-03-2018 SMD44_RS17525 b2279c15b80265a2290770ff448a6875 106 SUPERFAMILY SSF103481 4 104 3.66E-17 T 28-03-2018 SMD44_RS17525 b2279c15b80265a2290770ff448a6875 106 Pfam PF00893 Small Multidrug Resistance protein 1 92 1.4E-17 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMD44_RS05730 aea61f1a2d731ec74ddfbd08c58aee29 271 Hamap MF_01384 Urease accessory protein UreD [ureD]. 23 267 20.054 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 SMD44_RS05730 aea61f1a2d731ec74ddfbd08c58aee29 271 Pfam PF01774 UreD urease accessory protein 63 220 2.5E-27 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 SMD44_RS34375 4a7b74cb93061a0fc4b61e9fc4f69da5 288 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 6 264 6.4E-58 T 28-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMD44_RS05225 f8e687e5b815fda2c9efc2399e236cc9 136 Gene3D G3DSA:3.30.429.10 1 131 5.4E-27 T 28-03-2018 SMD44_RS05225 f8e687e5b815fda2c9efc2399e236cc9 136 SUPERFAMILY SSF55331 2 126 8.77E-31 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily SMD44_RS05225 f8e687e5b815fda2c9efc2399e236cc9 136 Pfam PF14552 Tautomerase enzyme 37 119 5.7E-25 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 SMD44_RS25270 af05a0ca5f69bf0985f55a617064a859 364 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 78 134 1.0E-21 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25270 af05a0ca5f69bf0985f55a617064a859 364 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 29 145 3.0E-35 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25270 af05a0ca5f69bf0985f55a617064a859 364 SUPERFAMILY SSF143243 18 153 3.4E-39 T 28-03-2018 SMD44_RS06470 ee01688bcd2b0f5dd35ff1ac804a2fff 120 Pfam PF11236 Protein of unknown function (DUF3037) 2 116 1.7E-39 T 28-03-2018 IPR021398 Protein of unknown function DUF3037 SMD44_RS19820 0694499e2093dae463c692895a26ebf6 90 Pfam PF00550 Phosphopantetheine attachment site 12 75 1.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS19820 0694499e2093dae463c692895a26ebf6 90 SUPERFAMILY SSF47336 9 84 6.54E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS19820 0694499e2093dae463c692895a26ebf6 90 Gene3D G3DSA:1.10.1200.10 4 85 3.2E-14 T 28-03-2018 SMD44_RS29890 f8529c33d3e572d5c52a57e323dab6b1 332 Pfam PF00248 Aldo/keto reductase family 16 323 3.3E-61 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS29890 f8529c33d3e572d5c52a57e323dab6b1 332 SUPERFAMILY SSF51430 3 324 6.68E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS29890 f8529c33d3e572d5c52a57e323dab6b1 332 Gene3D G3DSA:3.20.20.100 1 330 6.4E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS32485 63f2e17dada1a7e8bcbbbb3a525c34f5 82 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 42 3.7E-10 T 28-03-2018 SMD44_RS32485 63f2e17dada1a7e8bcbbbb3a525c34f5 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 42 3.3E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMD44_RS32485 63f2e17dada1a7e8bcbbbb3a525c34f5 82 Gene3D G3DSA:3.40.1620.10 1 77 2.4E-12 T 28-03-2018 SMD44_RS32485 63f2e17dada1a7e8bcbbbb3a525c34f5 82 SUPERFAMILY SSF143120 4 44 2.88E-7 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMD44_RS06295 024cbc95e0d71868563b17244f25078f 539 Pfam PF00135 Carboxylesterase family 30 510 1.8E-113 T 28-03-2018 IPR002018 Carboxylesterase, type B SMD44_RS06295 024cbc95e0d71868563b17244f25078f 539 Gene3D G3DSA:3.40.50.1820 26 539 8.0E-133 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06295 024cbc95e0d71868563b17244f25078f 539 SUPERFAMILY SSF53474 29 535 1.4E-117 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS06295 024cbc95e0d71868563b17244f25078f 539 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 212 227 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site SMD44_RS16675 559cced2314db55dc5ba792ef331ef54 124 Gene3D G3DSA:3.30.450.30 1 123 3.3E-22 T 28-03-2018 SMD44_RS39850 23236117ec7fcfc40b3faff8e657097e 374 Pfam PF02625 XdhC and CoxI family 11 78 8.9E-23 T 28-03-2018 IPR003777 XdhC- CoxI SMD44_RS39850 23236117ec7fcfc40b3faff8e657097e 374 Pfam PF02625 XdhC and CoxI family 118 182 2.1E-12 T 28-03-2018 IPR003777 XdhC- CoxI SMD44_RS39850 23236117ec7fcfc40b3faff8e657097e 374 Pfam PF13478 XdhC Rossmann domain 206 348 4.7E-42 T 28-03-2018 IPR027051 XdhC Rossmann domain SMD44_RS01625 b4ddcfbf30a293f9af4a094511c89176 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 227 2.3E-7 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS01625 b4ddcfbf30a293f9af4a094511c89176 313 Gene3D G3DSA:3.40.50.720 1 306 1.7E-25 T 28-03-2018 SMD44_RS01625 b4ddcfbf30a293f9af4a094511c89176 313 SUPERFAMILY SSF51735 1 294 1.1E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS02735 a98cd2f4c2b96883b2a901d7b58db52b 436 Gene3D G3DSA:3.40.190.10 36 168 8.1E-22 T 28-03-2018 SMD44_RS02735 a98cd2f4c2b96883b2a901d7b58db52b 436 Gene3D G3DSA:3.40.190.10 169 380 4.7E-44 T 28-03-2018 SMD44_RS02735 a98cd2f4c2b96883b2a901d7b58db52b 436 SUPERFAMILY SSF53850 37 433 6.21E-72 T 28-03-2018 SMD44_RS02735 a98cd2f4c2b96883b2a901d7b58db52b 436 Pfam PF01547 Bacterial extracellular solute-binding protein 54 346 8.9E-43 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS31350 a7bcf25a4fc3225f9435141f6a461983 97 Gene3D G3DSA:1.20.120.20 1 73 2.0E-4 T 28-03-2018 SMD44_RS31350 a7bcf25a4fc3225f9435141f6a461983 97 Pfam PF14013 MT0933-like antitoxin protein 15 63 4.4E-17 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 SMD44_RS37175 583c4f4ad30d16142d595d4a920c3542 360 Pfam PF13407 Periplasmic binding protein domain 54 315 2.2E-49 T 28-03-2018 IPR025997 Periplasmic binding protein SMD44_RS37175 583c4f4ad30d16142d595d4a920c3542 360 Gene3D G3DSA:3.40.50.2300 47 167 1.9E-19 T 28-03-2018 SMD44_RS37175 583c4f4ad30d16142d595d4a920c3542 360 Gene3D G3DSA:3.40.50.2300 168 307 1.0E-24 T 28-03-2018 SMD44_RS37175 583c4f4ad30d16142d595d4a920c3542 360 SUPERFAMILY SSF53822 51 351 3.03E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS07865 ae6f7ab24cd80fabfa03149a178a014e 398 Pfam PF02638 Glycosyl hydrolase-like 10 28 342 9.1E-84 T 28-03-2018 IPR003790 Glycosyl hydrolase-like 10 SMD44_RS07865 ae6f7ab24cd80fabfa03149a178a014e 398 SUPERFAMILY SSF51445 85 318 4.13E-18 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS07865 ae6f7ab24cd80fabfa03149a178a014e 398 Gene3D G3DSA:3.20.20.80 33 373 1.0E-41 T 28-03-2018 SMD44_RS11550 b66b30107c8c5ac99074c5e261f4e6b5 348 SUPERFAMILY SSF51735 41 304 7.94E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS11550 b66b30107c8c5ac99074c5e261f4e6b5 348 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 236 2.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11550 b66b30107c8c5ac99074c5e261f4e6b5 348 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 148 2.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11550 b66b30107c8c5ac99074c5e261f4e6b5 348 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 63 2.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11550 b66b30107c8c5ac99074c5e261f4e6b5 348 Pfam PF00106 short chain dehydrogenase 45 254 4.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS11550 b66b30107c8c5ac99074c5e261f4e6b5 348 Gene3D G3DSA:3.40.50.720 40 316 1.7E-31 T 28-03-2018 SMD44_RS11750 88f411068b1b0409ee866b5d1e0aa854 122 Pfam PF03960 ArsC family 55 118 7.1E-9 T 28-03-2018 IPR006660 Arsenate reductase-like SMD44_RS11750 88f411068b1b0409ee866b5d1e0aa854 122 Gene3D G3DSA:3.40.30.10 1 120 8.7E-32 T 28-03-2018 SMD44_RS11750 88f411068b1b0409ee866b5d1e0aa854 122 SUPERFAMILY SSF52833 2 120 3.1E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS27515 fe6e77d6a6579ead70ef0ec9d994b1ad 138 Pfam PF02467 Transcription factor WhiB 42 110 1.7E-21 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS27515 fe6e77d6a6579ead70ef0ec9d994b1ad 138 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 9 118 18.365 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS20650 17c63e8321b1eba87d435862b09ff69a 144 SUPERFAMILY SSF46785 24 137 3.3E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20650 17c63e8321b1eba87d435862b09ff69a 144 Gene3D G3DSA:1.10.10.10 20 144 6.5E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20650 17c63e8321b1eba87d435862b09ff69a 144 Pfam PF01638 HxlR-like helix-turn-helix 38 123 3.7E-27 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS17825 ce13ec61513859b29bf252bc3a20a3fe 148 SUPERFAMILY SSF103473 17 129 1.05E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS17825 ce13ec61513859b29bf252bc3a20a3fe 148 Gene3D G3DSA:1.20.1250.20 1 142 0.001 T 28-03-2018 SMD44_RS15660 b6143d1d327c50ad5cc4794aa449daa8 262 Gene3D G3DSA:3.40.50.300 2 238 4.9E-62 T 28-03-2018 SMD44_RS15660 b6143d1d327c50ad5cc4794aa449daa8 262 SMART SM00382 28 212 1.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS15660 b6143d1d327c50ad5cc4794aa449daa8 262 Pfam PF00005 ABC transporter 20 168 1.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS15660 b6143d1d327c50ad5cc4794aa449daa8 262 SUPERFAMILY SSF52540 3 226 2.07E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13515 b6537dfb1687ae7c96f5cd16052d870e 338 SUPERFAMILY SSF51430 1 316 1.17E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS13515 b6537dfb1687ae7c96f5cd16052d870e 338 Pfam PF00248 Aldo/keto reductase family 16 315 2.1E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS13515 b6537dfb1687ae7c96f5cd16052d870e 338 Gene3D G3DSA:3.20.20.100 1 337 2.7E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS08355 29b88dd7a2b1d9edf57363d2299e700e 280 Pfam PF03777 Small secreted domain (DUF320) 24 79 4.4E-26 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS08355 29b88dd7a2b1d9edf57363d2299e700e 280 Pfam PF03777 Small secreted domain (DUF320) 100 153 2.4E-21 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS33490 2cb8ce1c8922350775be6eda313a67a1 403 Gene3D G3DSA:3.90.1150.10 280 403 1.2E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS33490 2cb8ce1c8922350775be6eda313a67a1 403 SUPERFAMILY SSF53383 4 399 9.84E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS33490 2cb8ce1c8922350775be6eda313a67a1 403 Pfam PF00155 Aminotransferase class I and II 34 393 1.6E-50 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS33490 2cb8ce1c8922350775be6eda313a67a1 403 Gene3D G3DSA:3.40.640.10 52 279 2.4E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS42145 9a44a1fafda11368239d2cd0cf25fdd0 449 Gene3D G3DSA:3.40.710.10 15 344 5.9E-68 T 28-03-2018 SMD44_RS42145 9a44a1fafda11368239d2cd0cf25fdd0 449 SUPERFAMILY SSF56601 19 336 1.53E-66 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS42145 9a44a1fafda11368239d2cd0cf25fdd0 449 Pfam PF00144 Beta-lactamase 31 329 4.5E-52 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS33435 aad76109c7d83ea5b74ece67e0a11253 68 Pfam PF04149 Domain of unknown function (DUF397) 8 60 2.9E-22 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS17335 e4887e6bc33b26d20620ad4fb2e6221b 283 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 12 257 1.4E-89 T 28-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 SMD44_RS17335 e4887e6bc33b26d20620ad4fb2e6221b 283 Gene3D G3DSA:3.40.50.1580 3 276 5.5E-44 T 28-03-2018 SMD44_RS17335 e4887e6bc33b26d20620ad4fb2e6221b 283 SUPERFAMILY SSF53167 10 272 1.02E-82 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS17335 e4887e6bc33b26d20620ad4fb2e6221b 283 Pfam PF01048 Phosphorylase superfamily 12 254 1.1E-41 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD44_RS17335 e4887e6bc33b26d20620ad4fb2e6221b 283 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 10 278 42.255 T 28-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 SMD44_RS03805 b719c46537feb2a35c2f49e9e4a55505 158 SUPERFAMILY SSF54427 14 130 1.97E-19 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS03805 b719c46537feb2a35c2f49e9e4a55505 158 Pfam PF12680 SnoaL-like domain 18 123 8.5E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS03805 b719c46537feb2a35c2f49e9e4a55505 158 Gene3D G3DSA:3.10.450.50 1 150 3.8E-27 T 28-03-2018 SMD44_RS31935 df115aee7aab4b9e42ada89917e25e21 682 Pfam PF13520 Amino acid permease 58 478 7.6E-34 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS30375 61d8885cdf780051f3b8ecdeb38a6890 196 Gene3D G3DSA:3.40.50.360 1 193 5.8E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS30375 61d8885cdf780051f3b8ecdeb38a6890 196 SUPERFAMILY SSF52218 6 185 1.83E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain SMD44_RS30375 61d8885cdf780051f3b8ecdeb38a6890 196 Pfam PF03358 NADPH-dependent FMN reductase 32 124 1.4E-10 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD44_RS13310 433497f1f97777076b4f0a89b217195e 577 Pfam PF00664 ABC transporter transmembrane region 18 288 5.2E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS13310 433497f1f97777076b4f0a89b217195e 577 SUPERFAMILY SSF90123 6 315 6.67E-72 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS13310 433497f1f97777076b4f0a89b217195e 577 Gene3D G3DSA:1.20.1560.10 1 316 4.2E-70 T 28-03-2018 SMD44_RS13310 433497f1f97777076b4f0a89b217195e 577 SUPERFAMILY SSF52540 328 570 5.21E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS13310 433497f1f97777076b4f0a89b217195e 577 SMART SM00382 360 552 4.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS13310 433497f1f97777076b4f0a89b217195e 577 Pfam PF00005 ABC transporter 351 498 1.3E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS13310 433497f1f97777076b4f0a89b217195e 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD44_RS13310 433497f1f97777076b4f0a89b217195e 577 Gene3D G3DSA:3.40.50.300 323 576 3.5E-65 T 28-03-2018 SMD44_RS28735 f4e8c52016b8b5cc8f31607cff1fc05a 200 SUPERFAMILY SSF63817 52 199 1.41E-13 T 28-03-2018 IPR023365 Sortase domain SMD44_RS28735 f4e8c52016b8b5cc8f31607cff1fc05a 200 Pfam PF04203 Sortase family 87 199 8.3E-14 T 28-03-2018 IPR005754 Sortase family SMD44_RS28735 f4e8c52016b8b5cc8f31607cff1fc05a 200 Gene3D G3DSA:2.40.260.10 25 200 1.9E-23 T 28-03-2018 IPR023365 Sortase domain SMD44_RS18390 7bfd344210243c4b2a0727fa739a115b 343 Gene3D G3DSA:2.130.10.10 181 308 2.4E-6 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS18390 7bfd344210243c4b2a0727fa739a115b 343 SUPERFAMILY SSF75011 58 281 9.02E-18 T 28-03-2018 SMD44_RS18390 7bfd344210243c4b2a0727fa739a115b 343 Gene3D G3DSA:2.130.10.10 27 180 7.3E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS24095 218ffefbefe7c963dddf5d89c8d8d064 271 Gene3D G3DSA:3.40.1190.20 5 197 2.3E-4 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS24095 218ffefbefe7c963dddf5d89c8d8d064 271 Pfam PF15698 Phosphatase 7 269 1.1E-117 T 28-03-2018 IPR031423 Uncharacterised phosphatase SCO2771 SMD44_RS10825 9862467464aa4114afaf488a95441906 214 Gene3D G3DSA:1.10.10.10 6 128 5.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10825 9862467464aa4114afaf488a95441906 214 SMART SM00418 31 111 3.0E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS10825 9862467464aa4114afaf488a95441906 214 SUPERFAMILY SSF46785 27 116 8.86E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS10825 9862467464aa4114afaf488a95441906 214 Pfam PF12840 Helix-turn-helix domain 33 87 6.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS20010 0e4c96656c8906fc094d776582159e5f 273 Pfam PF01061 ABC-2 type transporter 29 234 4.9E-18 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS20010 0e4c96656c8906fc094d776582159e5f 273 PIRSF PIRSF006648 1 269 1.1E-18 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS15825 23a69228e74526d5a4c9f38129a95f08 232 Gene3D G3DSA:3.40.1000.10 67 232 4.1E-7 T 28-03-2018 SMD44_RS03995 7c896ed00d164c0a3efc078e27eaea28 166 Gene3D G3DSA:3.30.530.20 14 166 1.2E-19 T 28-03-2018 IPR023393 START-like domain SMD44_RS03995 7c896ed00d164c0a3efc078e27eaea28 166 SUPERFAMILY SSF55961 17 149 1.16E-20 T 28-03-2018 SMD44_RS03995 7c896ed00d164c0a3efc078e27eaea28 166 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 19 160 1.3E-21 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS37815 8ecb766eaa78588a85e7eb046f841d06 373 Gene3D G3DSA:3.75.10.10 17 373 2.4E-69 T 28-03-2018 SMD44_RS37815 8ecb766eaa78588a85e7eb046f841d06 373 SUPERFAMILY SSF55909 17 372 4.1E-108 T 28-03-2018 SMD44_RS40790 fd2ef3b7945634ac4dcb453b19b98c90 62 Pfam PF14020 Protein of unknown function (DUF4236) 4 52 3.4E-12 T 28-03-2018 IPR025330 Domain of unknown function DUF4236 SMD44_RS15625 c5c16ab4383414d4be379d41fc602e5c 77 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 4 63 1.1E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMD44_RS15625 c5c16ab4383414d4be379d41fc602e5c 77 Pfam PF00367 phosphotransferase system, EIIB 7 39 9.9E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SMD44_RS15625 c5c16ab4383414d4be379d41fc602e5c 77 SUPERFAMILY SSF55604 5 76 1.44E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMD44_RS15625 c5c16ab4383414d4be379d41fc602e5c 77 Gene3D G3DSA:3.30.1360.60 2 77 1.6E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMD44_RS10450 6deabc2c7c164399860a2ad854064959 152 SMART SM00363 14 78 3.2E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS10450 6deabc2c7c164399860a2ad854064959 152 Gene3D G3DSA:3.10.290.10 11 108 8.8E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS10450 6deabc2c7c164399860a2ad854064959 152 SUPERFAMILY SSF55174 14 97 5.36E-21 T 28-03-2018 SMD44_RS10450 6deabc2c7c164399860a2ad854064959 152 Pfam PF01479 S4 domain 14 60 2.0E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMD44_RS10450 6deabc2c7c164399860a2ad854064959 152 PIRSF PIRSF016821 11 134 5.6E-42 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 SMD44_RS11310 a0d03d27348249f32a44cbcd2a904756 350 Gene3D G3DSA:3.90.1720.10 229 345 1.6E-35 T 28-03-2018 SMD44_RS11310 a0d03d27348249f32a44cbcd2a904756 350 Pfam PF00877 NlpC/P60 family 250 344 5.1E-24 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMD44_RS11310 a0d03d27348249f32a44cbcd2a904756 350 SUPERFAMILY SSF54001 233 341 3.78E-36 T 28-03-2018 SMD44_RS11310 a0d03d27348249f32a44cbcd2a904756 350 Gene3D G3DSA:1.20.120.330 19 204 2.8E-12 T 28-03-2018 SMD44_RS11980 de3496426460897c5f6805b69d0ba9cc 285 Pfam PF01061 ABC-2 type transporter 37 249 1.9E-35 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS11980 de3496426460897c5f6805b69d0ba9cc 285 PIRSF PIRSF006648 11 285 7.7E-88 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS25020 fd994ced33a129bc7b1f0a4c540bf0bd 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 119 17.775 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 SMD44_RS25020 fd994ced33a129bc7b1f0a4c540bf0bd 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 118 2.3E-36 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS30650 5cd1e9bdf1bfa1896b971e36b1a76054 932 Gene3D G3DSA:2.60.60.30 630 781 1.1E-18 T 28-03-2018 SMD44_RS31480 b32d2210a141f2f06588c2b56b6fd091 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 84 197 5.9E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS31480 b32d2210a141f2f06588c2b56b6fd091 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 1.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS31480 b32d2210a141f2f06588c2b56b6fd091 204 Gene3D G3DSA:1.10.357.10 69 201 1.4E-17 T 28-03-2018 SMD44_RS31480 b32d2210a141f2f06588c2b56b6fd091 204 Gene3D G3DSA:1.10.10.60 8 68 1.6E-14 T 28-03-2018 SMD44_RS31480 b32d2210a141f2f06588c2b56b6fd091 204 SUPERFAMILY SSF48498 88 202 1.33E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS31480 b32d2210a141f2f06588c2b56b6fd091 204 SUPERFAMILY SSF46689 17 82 1.39E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS02780 baa71947946d220b060decdae72dfc99 395 SUPERFAMILY SSF55486 155 247 1.09E-6 T 28-03-2018 SMD44_RS02780 baa71947946d220b060decdae72dfc99 395 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 74 327 2.7E-35 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD44_RS40735 f8e174ce96b16ce0a7f84ab93399d0dd 503 PRINTS PR00133 Glycosyl hydrolase family 3 signature 244 262 4.7E-6 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS40735 f8e174ce96b16ce0a7f84ab93399d0dd 503 PRINTS PR00133 Glycosyl hydrolase family 3 signature 168 184 4.7E-6 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS40735 f8e174ce96b16ce0a7f84ab93399d0dd 503 PRINTS PR00133 Glycosyl hydrolase family 3 signature 90 109 4.7E-6 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS40735 f8e174ce96b16ce0a7f84ab93399d0dd 503 Gene3D G3DSA:3.20.20.300 14 365 3.1E-86 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS40735 f8e174ce96b16ce0a7f84ab93399d0dd 503 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 37 326 2.1E-74 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS40735 f8e174ce96b16ce0a7f84ab93399d0dd 503 SUPERFAMILY SSF51445 16 328 1.37E-80 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS10215 8c6d154fc69b9411199904d62b8d447e 356 Gene3D G3DSA:3.40.50.10740 7 168 4.5E-39 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain SMD44_RS10215 8c6d154fc69b9411199904d62b8d447e 356 Gene3D G3DSA:3.50.30.60 169 356 1.5E-39 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain SMD44_RS10215 8c6d154fc69b9411199904d62b8d447e 356 Pfam PF02016 LD-carboxypeptidase 22 345 8.9E-60 T 28-03-2018 IPR003507 Peptidase family S66 SMD44_RS10215 8c6d154fc69b9411199904d62b8d447e 356 SUPERFAMILY SSF52317 10 169 1.24E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like SMD44_RS10215 8c6d154fc69b9411199904d62b8d447e 356 SUPERFAMILY SSF141986 209 351 2.48E-13 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain SMD44_RS13905 ac697b932224d41ff5f3b6b258ff955d 485 Pfam PF09594 Glycosyltransferase family 87 119 362 2.2E-52 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD44_RS19380 990bf83e586bbcac52f6b8c07bfc5c78 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 331 1.4E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS19380 990bf83e586bbcac52f6b8c07bfc5c78 341 Gene3D G3DSA:1.10.3720.10 46 339 6.4E-35 T 28-03-2018 SMD44_RS19380 990bf83e586bbcac52f6b8c07bfc5c78 341 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 37 333 7.5E-86 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 SMD44_RS19380 990bf83e586bbcac52f6b8c07bfc5c78 341 SUPERFAMILY SSF161098 54 325 5.89E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS14805 45899844f91d34654a8907a95514493b 370 SUPERFAMILY SSF51569 38 317 3.77E-14 T 28-03-2018 SMD44_RS14805 45899844f91d34654a8907a95514493b 370 Pfam PF06187 Protein of unknown function (DUF993) 8 368 2.9E-179 T 28-03-2018 IPR009334 Protein of unknown function DUF993 SMD44_RS14805 45899844f91d34654a8907a95514493b 370 Gene3D G3DSA:3.20.20.70 18 342 2.9E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 Pfam PF01966 HD domain 73 148 4.7E-14 T 28-03-2018 IPR006674 HD domain SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 435 3.1E-74 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 Gene3D G3DSA:1.10.3210.10 7 222 7.6E-65 T 28-03-2018 SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 SUPERFAMILY SSF109604 25 178 1.93E-55 T 28-03-2018 SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 SUPERFAMILY SSF109604 214 262 1.93E-55 T 28-03-2018 SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 SUPERFAMILY SSF109604 296 428 1.93E-55 T 28-03-2018 SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 SMART SM00471 69 243 2.4E-11 T 28-03-2018 IPR003607 HD/PDEase domain SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 Gene3D G3DSA:1.10.3410.10 223 362 2.8E-31 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 Pfam PF13286 Phosphohydrolase-associated domain 342 433 1.3E-19 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain SMD44_RS13340 dedea8988359094b482cff1d8a100cbc 441 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 7 435 30.529 T 28-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 SMD44_RS39370 a413fb514b7080f3ced87c13f8f11933 144 Pfam PF03259 Roadblock/LC7 domain 15 105 1.4E-27 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS39370 a413fb514b7080f3ced87c13f8f11933 144 SMART SM00960 16 106 5.2E-32 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMD44_RS39370 a413fb514b7080f3ced87c13f8f11933 144 Gene3D G3DSA:3.30.450.30 11 138 1.2E-41 T 28-03-2018 SMD44_RS39370 a413fb514b7080f3ced87c13f8f11933 144 SUPERFAMILY SSF103196 8 134 8.55E-37 T 28-03-2018 SMD44_RS10995 e3527e09a5a27a4941c742bf447c2b2e 94 Pfam PF02325 YGGT family 10 90 5.5E-12 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 SMD44_RS25215 2192912ed476a3379ac67b9be859e644 292 SUPERFAMILY SSF51735 21 260 1.22E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS25215 2192912ed476a3379ac67b9be859e644 292 Gene3D G3DSA:3.40.50.720 17 146 2.0E-16 T 28-03-2018 SMD44_RS25215 2192912ed476a3379ac67b9be859e644 292 Gene3D G3DSA:3.90.25.10 147 284 1.3E-8 T 28-03-2018 SMD44_RS25215 2192912ed476a3379ac67b9be859e644 292 Pfam PF13460 NAD(P)H-binding 27 188 4.0E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS20950 2cf642bd6c3e91ee60b2113db4d08301 252 SUPERFAMILY SSF53474 3 250 1.29E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS20950 2cf642bd6c3e91ee60b2113db4d08301 252 Gene3D G3DSA:3.40.50.1820 2 250 1.9E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS20950 2cf642bd6c3e91ee60b2113db4d08301 252 Pfam PF12697 Alpha/beta hydrolase family 24 244 2.7E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS20950 2cf642bd6c3e91ee60b2113db4d08301 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 196 210 4.0E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS20950 2cf642bd6c3e91ee60b2113db4d08301 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 4.0E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS20950 2cf642bd6c3e91ee60b2113db4d08301 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 4.0E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS20950 2cf642bd6c3e91ee60b2113db4d08301 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 4.0E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMD44_RS01815 58572313a9dd6d9cb989497f40fc8518 340 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 5 336 5.4E-82 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 SMD44_RS01815 58572313a9dd6d9cb989497f40fc8518 340 SUPERFAMILY SSF51556 4 338 2.72E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase SMD44_RS01815 58572313a9dd6d9cb989497f40fc8518 340 Gene3D G3DSA:3.20.20.140 243 339 1.1E-22 T 28-03-2018 SMD44_RS01815 58572313a9dd6d9cb989497f40fc8518 340 Gene3D G3DSA:3.20.20.140 3 242 2.3E-66 T 28-03-2018 SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 59 467 5.1E-107 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 72 91 1.8E-26 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 444 457 1.8E-26 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 304 326 1.8E-26 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 362 376 1.8E-26 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 377 391 1.8E-26 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 Gene3D G3DSA:3.40.710.10 29 494 2.4E-41 T 28-03-2018 SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 SUPERFAMILY SSF56601 30 479 1.11E-93 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS16030 c1972573e1cf8017ddb9b28174d9ccf6 519 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 34 486 3.6E-127 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD44_RS18915 0961b7a792435bfc28e936e26e52aa56 417 SUPERFAMILY SSF51905 357 373 1.29E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS18915 0961b7a792435bfc28e936e26e52aa56 417 SUPERFAMILY SSF51905 14 263 1.29E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS18915 0961b7a792435bfc28e936e26e52aa56 417 Gene3D G3DSA:3.50.50.60 14 411 3.3E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS18915 0961b7a792435bfc28e936e26e52aa56 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 17 39 1.4E-5 T 28-03-2018 SMD44_RS18915 0961b7a792435bfc28e936e26e52aa56 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 364 371 1.4E-5 T 28-03-2018 SMD44_RS18915 0961b7a792435bfc28e936e26e52aa56 417 Pfam PF13450 NAD(P)-binding Rossmann-like domain 20 79 3.7E-10 T 28-03-2018 SMD44_RS26055 d6dec2a632972fe5a40dd6610747c8fd 208 Pfam PF06271 RDD family 79 202 3.7E-25 T 28-03-2018 IPR010432 RDD SMD44_RS38100 77eeddabf17cdd6845c55dc3c786238c 200 SUPERFAMILY SSF48498 89 178 2.77E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD44_RS38100 77eeddabf17cdd6845c55dc3c786238c 200 Gene3D G3DSA:1.10.10.60 55 85 5.3E-12 T 28-03-2018 SMD44_RS38100 77eeddabf17cdd6845c55dc3c786238c 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS38100 77eeddabf17cdd6845c55dc3c786238c 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS38100 77eeddabf17cdd6845c55dc3c786238c 200 SUPERFAMILY SSF46689 18 83 8.48E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS38100 77eeddabf17cdd6845c55dc3c786238c 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 9.4E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD44_RS38100 77eeddabf17cdd6845c55dc3c786238c 200 Gene3D G3DSA:1.10.10.60 1 54 1.7E-19 T 28-03-2018 SMD44_RS38100 77eeddabf17cdd6845c55dc3c786238c 200 Gene3D G3DSA:1.10.357.10 86 199 3.5E-12 T 28-03-2018 SMD44_RS28670 84c9d787c64d9b637a0d23d3a09d06dd 210 Pfam PF03029 Conserved hypothetical ATP binding protein 38 206 1.9E-27 T 28-03-2018 IPR004130 GPN-loop GTPase SMD44_RS28670 84c9d787c64d9b637a0d23d3a09d06dd 210 SUPERFAMILY SSF52540 33 207 1.04E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS28670 84c9d787c64d9b637a0d23d3a09d06dd 210 Gene3D G3DSA:3.40.50.300 21 210 4.6E-16 T 28-03-2018 SMD44_RS12495 7507b050ece1762c4455ca5810e39ca8 122 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 75 1.0E-16 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD44_RS12495 7507b050ece1762c4455ca5810e39ca8 122 SUPERFAMILY SSF54909 1 80 1.26E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS12495 7507b050ece1762c4455ca5810e39ca8 122 Gene3D G3DSA:3.30.70.100 1 117 2.1E-31 T 28-03-2018 SMD44_RS03385 c83d985a44890b89bdf3ea5420e7488d 81 Pfam PF04149 Domain of unknown function (DUF397) 26 74 3.2E-10 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS24235 c4cd4183d51f87295c9330ec83dca9c3 381 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 64 371 4.2E-58 T 28-03-2018 IPR003776 YcaO-like domain SMD44_RS24235 c4cd4183d51f87295c9330ec83dca9c3 381 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 17 297 3.6E-59 T 28-03-2018 IPR003776 YcaO-like domain SMD44_RS13080 ed5b91c3f180d2f84ccc909eacff8985 256 Gene3D G3DSA:2.60.200.20 3 93 1.4E-5 T 28-03-2018 SMD44_RS13080 ed5b91c3f180d2f84ccc909eacff8985 256 SUPERFAMILY SSF49879 10 61 8.14E-6 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMD44_RS30065 82b78d1203bfd1c3712dc59b0ec453de 378 Gene3D G3DSA:2.130.10.10 178 247 8.9E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS30065 82b78d1203bfd1c3712dc59b0ec453de 378 Gene3D G3DSA:2.130.10.10 30 177 1.9E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS30065 82b78d1203bfd1c3712dc59b0ec453de 378 SUPERFAMILY SSF82171 61 360 3.79E-20 T 28-03-2018 SMD44_RS30065 82b78d1203bfd1c3712dc59b0ec453de 378 Gene3D G3DSA:2.140.10.30 248 378 7.8E-10 T 28-03-2018 SMD44_RS31975 2aebcfa89b6d576382f8d2e784d1ef86 260 Pfam PF00999 Sodium/hydrogen exchanger family 2 252 3.3E-26 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD44_RS31745 970dc79dbe975332364314e1961b8000 257 Pfam PF12502 Protein of unknown function (DUF3710) 51 224 1.3E-60 T 28-03-2018 IPR022183 Protein of unknown function DUF3710 SMD44_RS13920 a170e37a8fdafb8af195e4b3101d9c3b 301 SMART SM00530 32 104 3.7E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS13920 a170e37a8fdafb8af195e4b3101d9c3b 301 Gene3D G3DSA:1.10.260.40 19 128 7.9E-14 T 28-03-2018 SMD44_RS13920 a170e37a8fdafb8af195e4b3101d9c3b 301 SUPERFAMILY SSF47413 52 103 7.5E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS13920 a170e37a8fdafb8af195e4b3101d9c3b 301 Pfam PF13560 Helix-turn-helix domain 28 107 4.9E-18 T 28-03-2018 SMD44_RS23725 67023dff4e505b604ec7d053e7faa103 113 Gene3D G3DSA:3.10.450.50 1 110 7.5E-34 T 28-03-2018 SMD44_RS23725 67023dff4e505b604ec7d053e7faa103 113 Pfam PF13474 SnoaL-like domain 1 99 1.5E-25 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS23725 67023dff4e505b604ec7d053e7faa103 113 SUPERFAMILY SSF54427 2 99 6.77E-33 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS29435 3e618550fe5acf1ce3cd39df5cbf419b 500 SUPERFAMILY SSF56112 179 445 5.1E-18 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS29435 3e618550fe5acf1ce3cd39df5cbf419b 500 Gene3D G3DSA:3.90.1200.10 267 484 1.2E-13 T 28-03-2018 SMD44_RS28280 0b390bad8bcb8c10a498e62600e4d66b 434 Gene3D G3DSA:1.10.3210.10 196 402 3.6E-29 T 28-03-2018 SMD44_RS28280 0b390bad8bcb8c10a498e62600e4d66b 434 Pfam PF01966 HD domain 256 361 1.4E-5 T 28-03-2018 IPR006674 HD domain SMD44_RS28280 0b390bad8bcb8c10a498e62600e4d66b 434 SUPERFAMILY SSF109604 234 397 1.11E-13 T 28-03-2018 SMD44_RS38850 85b7baddf77de91abc5036ebfe712067 520 Gene3D G3DSA:3.40.50.300 247 481 7.5E-4 T 28-03-2018 SMD44_RS38850 85b7baddf77de91abc5036ebfe712067 520 Gene3D G3DSA:1.10.287.500 139 238 7.6E-4 T 28-03-2018 SMD44_RS38850 85b7baddf77de91abc5036ebfe712067 520 Pfam PF02706 Chain length determinant protein 16 95 1.1E-9 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 SMD44_RS41905 4118b78719ac42dd7d2f7dc64b96a20d 428 SUPERFAMILY SSF56112 29 239 3.28E-22 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS41905 4118b78719ac42dd7d2f7dc64b96a20d 428 Gene3D G3DSA:1.10.510.10 156 323 3.3E-7 T 28-03-2018 SMD44_RS41905 4118b78719ac42dd7d2f7dc64b96a20d 428 SMART SM00220 31 329 4.0E-5 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS41905 4118b78719ac42dd7d2f7dc64b96a20d 428 Pfam PF00069 Protein kinase domain 42 235 1.6E-13 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD44_RS41905 4118b78719ac42dd7d2f7dc64b96a20d 428 Gene3D G3DSA:3.30.200.20 15 155 1.4E-15 T 28-03-2018 SMD44_RS35720 f9284ee7b716283d0ad11e7961dd8537 216 Gene3D G3DSA:3.40.50.150 10 133 6.7E-4 T 28-03-2018 SMD44_RS29730 e34218dd718df4db3416cab37668a5d0 193 Pfam PF05995 Cysteine dioxygenase type I 67 172 3.9E-9 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SMD44_RS29730 e34218dd718df4db3416cab37668a5d0 193 SUPERFAMILY SSF51182 18 188 2.08E-41 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS29730 e34218dd718df4db3416cab37668a5d0 193 Gene3D G3DSA:2.60.120.10 12 191 1.6E-32 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS18435 275302ec93b839df736a036e84e3f707 271 Gene3D G3DSA:1.10.510.10 31 203 6.7E-21 T 28-03-2018 SMD44_RS18435 275302ec93b839df736a036e84e3f707 271 SUPERFAMILY SSF56112 33 234 5.06E-28 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS18435 275302ec93b839df736a036e84e3f707 271 Pfam PF01636 Phosphotransferase enzyme family 116 196 1.0E-13 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS01950 0f316ed80aa48b509c179621c99a649b 76 Gene3D G3DSA:1.10.1200.10 1 76 1.5E-16 T 28-03-2018 SMD44_RS01950 0f316ed80aa48b509c179621c99a649b 76 Pfam PF00550 Phosphopantetheine attachment site 4 68 2.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS01950 0f316ed80aa48b509c179621c99a649b 76 SUPERFAMILY SSF47336 1 74 4.84E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS19355 afe4a06827d1c4a004df7ec1f51ca38d 330 Gene3D G3DSA:1.20.1250.20 111 326 3.8E-5 T 28-03-2018 SMD44_RS31550 0a6f5f664127a228980e5deeb82732ec 162 Pfam PF07301 Protein of unknown function (DUF1453) 9 139 1.6E-6 T 28-03-2018 IPR009916 Protein of unknown function DUF1453 SMD44_RS06565 b9ee932f9a9d8e4114fd6cb8460ce243 259 Pfam PF02517 CAAX protease self-immunity 153 240 2.4E-15 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SMD44_RS10615 03d2e39a85708e62253a7a0bf87f9dfe 282 Pfam PF13460 NAD(P)H-binding 6 181 3.5E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS10615 03d2e39a85708e62253a7a0bf87f9dfe 282 SUPERFAMILY SSF51735 2 273 3.94E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS10615 03d2e39a85708e62253a7a0bf87f9dfe 282 Gene3D G3DSA:3.40.50.720 1 282 4.3E-27 T 28-03-2018 SMD44_RS10335 2c803063ff732b9911113c288ef53ae5 155 SUPERFAMILY SSF55874 25 117 2.89E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS10335 2c803063ff732b9911113c288ef53ae5 155 Gene3D G3DSA:3.30.565.10 1 125 2.9E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS10335 2c803063ff732b9911113c288ef53ae5 155 Pfam PF13581 Histidine kinase-like ATPase domain 2 104 2.4E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS15500 31d8483bdf71c21e4885bbe81df009ee 256 SMART SM00507 157 219 8.9E-5 T 28-03-2018 IPR003615 HNH nuclease SMD44_RS15500 31d8483bdf71c21e4885bbe81df009ee 256 Gene3D G3DSA:3.40.1800.10 147 233 8.8E-8 T 28-03-2018 SMD44_RS15500 31d8483bdf71c21e4885bbe81df009ee 256 Pfam PF01844 HNH endonuclease 170 223 4.5E-9 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMD44_RS41065 552ee7df6f04f3e39f01b296205fa0e1 138 Pfam PF13581 Histidine kinase-like ATPase domain 19 123 9.8E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41065 552ee7df6f04f3e39f01b296205fa0e1 138 Gene3D G3DSA:3.30.565.10 7 138 1.4E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS41065 552ee7df6f04f3e39f01b296205fa0e1 138 SUPERFAMILY SSF55874 38 121 7.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS28315 72f8ca2b8f04b760e3d6c99901e73750 346 Pfam PF00268 Ribonucleotide reductase, small chain 25 309 7.0E-83 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28315 72f8ca2b8f04b760e3d6c99901e73750 346 PIRSF PIRSF000355 3 344 1.1E-99 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD44_RS28315 72f8ca2b8f04b760e3d6c99901e73750 346 SUPERFAMILY SSF47240 11 333 6.96E-90 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS28315 72f8ca2b8f04b760e3d6c99901e73750 346 Gene3D G3DSA:1.10.620.20 2 318 1.7E-93 T 28-03-2018 SMD44_RS04880 585226b8efd9eba5b30f128f43e3b46c 201 Pfam PF01841 Transglutaminase-like superfamily 29 134 7.7E-11 T 28-03-2018 IPR002931 Transglutaminase-like SMD44_RS04880 585226b8efd9eba5b30f128f43e3b46c 201 SUPERFAMILY SSF54001 23 141 4.63E-16 T 28-03-2018 SMD44_RS02515 fce74e2d5d2728dbbcad876d3081219b 271 PIRSF PIRSF017393 1 271 1.1E-104 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS02515 fce74e2d5d2728dbbcad876d3081219b 271 Gene3D G3DSA:3.40.50.150 2 271 2.6E-48 T 28-03-2018 SMD44_RS02515 fce74e2d5d2728dbbcad876d3081219b 271 SUPERFAMILY SSF53335 20 255 3.87E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS02515 fce74e2d5d2728dbbcad876d3081219b 271 Pfam PF04672 S-adenosyl methyltransferase 11 271 2.6E-105 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD44_RS39580 58b514e07c71faa23439769b38a44a6b 82 SUPERFAMILY SSF47336 30 75 2.45E-5 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMD44_RS39580 58b514e07c71faa23439769b38a44a6b 82 Gene3D G3DSA:1.10.1200.10 4 82 5.1E-4 T 28-03-2018 SMD44_RS37805 2a652ad0b965c7dcf966b3614c3216a1 409 Pfam PF05175 Methyltransferase small domain 32 104 1.4E-8 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMD44_RS37805 2a652ad0b965c7dcf966b3614c3216a1 409 Gene3D G3DSA:3.40.50.150 14 117 1.8E-13 T 28-03-2018 SMD44_RS37805 2a652ad0b965c7dcf966b3614c3216a1 409 SUPERFAMILY SSF53335 17 102 2.11E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS16680 80f7782b87867bb899ff8904f7bb0cf7 277 Gene3D G3DSA:3.40.50.10490 99 264 6.1E-11 T 28-03-2018 SMD44_RS16680 80f7782b87867bb899ff8904f7bb0cf7 277 Pfam PF01418 Helix-turn-helix domain, rpiR family 15 76 3.2E-11 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMD44_RS16680 80f7782b87867bb899ff8904f7bb0cf7 277 Gene3D G3DSA:1.10.10.10 8 98 8.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16680 80f7782b87867bb899ff8904f7bb0cf7 277 SUPERFAMILY SSF53697 90 234 8.9E-8 T 28-03-2018 SMD44_RS16680 80f7782b87867bb899ff8904f7bb0cf7 277 SUPERFAMILY SSF46689 16 76 7.17E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMD44_RS40575 ae1b9d78553d524bd6b2a56ac322b8dd 279 Gene3D G3DSA:2.40.10.10 38 129 3.4E-10 T 28-03-2018 SMD44_RS40575 ae1b9d78553d524bd6b2a56ac322b8dd 279 SUPERFAMILY SSF50494 43 209 7.62E-10 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS25965 54cdc8630c1d3487d6ca3f17002971aa 559 Pfam PF01551 Peptidase family M23 454 547 4.4E-25 T 28-03-2018 IPR016047 Peptidase M23 SMD44_RS25965 54cdc8630c1d3487d6ca3f17002971aa 559 SUPERFAMILY SSF51261 421 551 1.41E-36 T 28-03-2018 IPR011055 Duplicated hybrid motif SMD44_RS25965 54cdc8630c1d3487d6ca3f17002971aa 559 Gene3D G3DSA:2.70.70.10 386 554 1.2E-37 T 28-03-2018 SMD44_RS13190 12a852c77bbaa3b8aeb2c3b53c4203d0 195 Gene3D G3DSA:2.60.60.30 20 188 8.3E-47 T 28-03-2018 SMD44_RS13190 12a852c77bbaa3b8aeb2c3b53c4203d0 195 Pfam PF02342 TerD domain 3 182 2.3E-46 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS20955 3a38914f808100e78d9b5064e7e314a5 440 Pfam PF14378 PAP2 superfamily 154 351 2.3E-17 T 28-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD44_RS26080 f61d3e2b4bf16198254351f7975bf19d 152 Gene3D G3DSA:2.60.40.20 88 152 2.3E-22 T 28-03-2018 SMD44_RS26080 f61d3e2b4bf16198254351f7975bf19d 152 Pfam PF01356 Alpha amylase inhibitor 90 144 4.0E-7 T 28-03-2018 IPR000833 Alpha-amylase inhibitor GO:0015066 SMD44_RS26080 f61d3e2b4bf16198254351f7975bf19d 152 SUPERFAMILY SSF49498 89 147 7.85E-8 T 28-03-2018 IPR000833 Alpha-amylase inhibitor GO:0015066 SMD44_RS08130 60d7011c2e96eaeea069222aee0c37d4 419 Pfam PF07690 Major Facilitator Superfamily 33 300 1.1E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS08130 60d7011c2e96eaeea069222aee0c37d4 419 SUPERFAMILY SSF103473 16 386 1.05E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS08130 60d7011c2e96eaeea069222aee0c37d4 419 Gene3D G3DSA:1.20.1250.20 203 387 7.8E-15 T 28-03-2018 SMD44_RS08130 60d7011c2e96eaeea069222aee0c37d4 419 Gene3D G3DSA:1.20.1250.20 7 202 3.9E-16 T 28-03-2018 SMD44_RS07080 429138b45205c71c327d254b57ec777f 264 SUPERFAMILY SSF56317 2 262 4.32E-70 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS07080 429138b45205c71c327d254b57ec777f 264 Gene3D G3DSA:3.60.110.10 1 262 2.7E-70 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS07080 429138b45205c71c327d254b57ec777f 264 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 140 160 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site SMD44_RS07080 429138b45205c71c327d254b57ec777f 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 242 3.5E-45 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD44_RS09125 0b5aa08157a68a3d8d6604b8358cb025 208 Gene3D G3DSA:3.90.79.10 1 188 1.8E-36 T 28-03-2018 SMD44_RS09125 0b5aa08157a68a3d8d6604b8358cb025 208 SUPERFAMILY SSF55811 9 182 1.07E-43 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD44_RS09125 0b5aa08157a68a3d8d6604b8358cb025 208 Pfam PF00293 NUDIX domain 48 161 5.3E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMD44_RS17345 e3cedffd63dbbd813ef92f557558d465 174 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 9 147 1.3E-22 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD44_RS17345 e3cedffd63dbbd813ef92f557558d465 174 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 19 32 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site SMD44_RS17345 e3cedffd63dbbd813ef92f557558d465 174 SUPERFAMILY SSF81330 18 133 3.4E-24 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD44_RS17345 e3cedffd63dbbd813ef92f557558d465 174 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 10 146 9.9E-34 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD44_RS17345 e3cedffd63dbbd813ef92f557558d465 174 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 12 26 6.5E-5 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD44_RS17345 e3cedffd63dbbd813ef92f557558d465 174 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 104 113 6.5E-5 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD44_RS17345 e3cedffd63dbbd813ef92f557558d465 174 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 94 102 6.5E-5 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD44_RS10720 d67a36b08f1e565792e8ef63d973b73c 335 Gene3D G3DSA:1.10.4080.10 15 316 2.7E-63 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10720 d67a36b08f1e565792e8ef63d973b73c 335 Pfam PF03747 ADP-ribosylglycohydrolase 25 299 1.8E-53 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS10720 d67a36b08f1e565792e8ef63d973b73c 335 SUPERFAMILY SSF101478 19 305 5.62E-50 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMD44_RS43070 78590ab8cf383bf556cec438aea8c164 134 Pfam PF07811 TadE-like protein 20 60 2.7E-9 T 28-03-2018 IPR012495 TadE-like SMD44_RS08680 1798511b14b8add22604593f7554bfce 532 Pfam PF14224 Domain of unknown function (DUF4331) 46 444 3.2E-158 T 28-03-2018 IPR025566 Protein of unknown function DUF4331 SMD44_RS38135 ab63d164d512970958374eb9df644a16 105 Pfam PF01374 Glycosyl hydrolase family 46 31 86 1.7E-20 T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMD44_RS38135 ab63d164d512970958374eb9df644a16 105 SUPERFAMILY SSF53955 19 93 7.87E-21 T 28-03-2018 IPR023346 Lysozyme-like domain SMD44_RS38135 ab63d164d512970958374eb9df644a16 105 Gene3D G3DSA:3.30.386.10 15 95 8.9E-28 T 28-03-2018 SMD44_RS26865 0326bbce0305c501758ecdc09464ee83 199 SUPERFAMILY SSF52540 1 164 6.31E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS26865 0326bbce0305c501758ecdc09464ee83 199 Gene3D G3DSA:3.40.50.300 1 168 1.7E-18 T 28-03-2018 SMD44_RS26865 0326bbce0305c501758ecdc09464ee83 199 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 3 142 2.7E-5 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 SMD44_RS08405 6d41f412f3b85b9344dd3bc4f1d62e38 112 Pfam PF11774 Lsr2 1 110 7.4E-29 T 28-03-2018 IPR024412 Lsr2 SMD44_RS08405 6d41f412f3b85b9344dd3bc4f1d62e38 112 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 111 2.0E-23 T 28-03-2018 IPR024412 Lsr2 SMD44_RS24615 8e91151f7a92933ae6d1cff4e9d00e27 152 Pfam PF06271 RDD family 14 121 2.3E-11 T 28-03-2018 IPR010432 RDD SMD44_RS20670 850642c1a94efa258cedc1e6a1205c0b 365 SUPERFAMILY SSF51395 1 362 8.18E-112 T 28-03-2018 SMD44_RS20670 850642c1a94efa258cedc1e6a1205c0b 365 Gene3D G3DSA:3.20.20.70 1 363 3.7E-123 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS20670 850642c1a94efa258cedc1e6a1205c0b 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 348 9.3E-68 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD44_RS01745 0c789a209d7ffa2984ac2340659a1db3 467 Gene3D G3DSA:3.40.309.10 250 449 1.5E-70 T 28-03-2018 SMD44_RS01745 0c789a209d7ffa2984ac2340659a1db3 467 SUPERFAMILY SSF53720 3 466 8.25E-145 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD44_RS01745 0c789a209d7ffa2984ac2340659a1db3 467 Pfam PF00171 Aldehyde dehydrogenase family 3 463 7.1E-139 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS01745 0c789a209d7ffa2984ac2340659a1db3 467 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 261 272 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD44_RS01745 0c789a209d7ffa2984ac2340659a1db3 467 Gene3D G3DSA:3.40.605.10 2 249 3.5E-71 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD44_RS01985 27a6fd4ae774387eabbbf4ece01254e9 283 Gene3D G3DSA:1.25.40.10 23 272 1.3E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS35025 6a1ad1d78b5e08a1061d0eb390046b94 300 Pfam PF05853 beta-keto acid cleavage enzyme 7 296 5.6E-102 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 SMD44_RS35025 6a1ad1d78b5e08a1061d0eb390046b94 300 Gene3D G3DSA:3.20.20.70 4 300 3.7E-108 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS21305 78cfc633c63d736e21c6d3731b8f0953 534 Pfam PF02397 Bacterial sugar transferase 348 529 5.3E-57 T 28-03-2018 IPR003362 Bacterial sugar transferase SMD44_RS21305 78cfc633c63d736e21c6d3731b8f0953 534 Gene3D G3DSA:3.40.50.720 178 315 3.4E-9 T 28-03-2018 SMD44_RS33790 03fc865c6ab613877bd95945fb4d19d7 161 Pfam PF03780 Asp23 family, cell envelope-related function 36 146 4.0E-33 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 SMD44_RS17095 95618654bb1dde5724c7ba42dc3aba05 580 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 83 310 8.8E-20 T 28-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 SMD44_RS17095 95618654bb1dde5724c7ba42dc3aba05 580 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 385 579 4.3E-23 T 28-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 SMD44_RS00585 0273e5f60d2a5eccf8f49a58b7b017ed 288 Gene3D G3DSA:3.40.630.30 112 286 3.0E-18 T 28-03-2018 SMD44_RS00585 0273e5f60d2a5eccf8f49a58b7b017ed 288 Pfam PF00583 Acetyltransferase (GNAT) family 193 275 3.2E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS00585 0273e5f60d2a5eccf8f49a58b7b017ed 288 SUPERFAMILY SSF55729 21 281 1.33E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS41570 b75293d0f770252d6df65a692e73047c 194 Pfam PF03595 Voltage-dependent anion channel 6 150 3.4E-13 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 SMD44_RS04365 0ed4fd3d103a13189797a25143048504 1233 Gene3D G3DSA:1.20.120.330 899 1127 5.8E-6 T 28-03-2018 SMD44_RS04365 0ed4fd3d103a13189797a25143048504 1233 Gene3D G3DSA:1.20.120.330 515 885 0.058 T 28-03-2018 SMD44_RS04365 0ed4fd3d103a13189797a25143048504 1233 Gene3D G3DSA:1.20.1480.30 253 503 0.04 T 28-03-2018 SMD44_RS16725 13b7e88df89dda05825b1a519c935100 97 Gene3D G3DSA:1.20.1250.10 12 95 8.5E-4 T 28-03-2018 SMD44_RS06285 8398c21b21fa0e0ed5effbb6860f7c6d 405 Gene3D G3DSA:3.40.710.10 26 394 5.4E-68 T 28-03-2018 SMD44_RS06285 8398c21b21fa0e0ed5effbb6860f7c6d 405 Pfam PF00144 Beta-lactamase 37 387 5.3E-59 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS06285 8398c21b21fa0e0ed5effbb6860f7c6d 405 SUPERFAMILY SSF56601 25 379 4.27E-70 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS03025 396d5d674b307992f1e6f27a23892970 213 SUPERFAMILY SSF55729 54 193 3.42E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS03025 396d5d674b307992f1e6f27a23892970 213 Gene3D G3DSA:3.40.630.30 33 207 2.0E-23 T 28-03-2018 SMD44_RS03025 396d5d674b307992f1e6f27a23892970 213 Pfam PF13302 Acetyltransferase (GNAT) domain 58 191 2.2E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS10305 0dcd9ace43be4a4218d8320cba4f38c4 238 Pfam PF10056 Uncharacterized conserved protein (DUF2293) 136 221 1.2E-24 T 28-03-2018 IPR018744 Domain of unknown function DUF2293 SMD44_RS39940 2332d24ff08f2129ea54d94e548dd26b 291 SMART SM00849 48 259 8.0E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS39940 2332d24ff08f2129ea54d94e548dd26b 291 Gene3D G3DSA:3.60.15.10 2 271 7.9E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS39940 2332d24ff08f2129ea54d94e548dd26b 291 Pfam PF00753 Metallo-beta-lactamase superfamily 47 259 4.7E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS39940 2332d24ff08f2129ea54d94e548dd26b 291 SUPERFAMILY SSF56281 26 269 6.81E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS14915 4800d4e512be888edea4f9ebbb70407f 260 Pfam PF15698 Phosphatase 9 258 3.6E-114 T 28-03-2018 IPR031423 Uncharacterised phosphatase SCO2771 SMD44_RS14915 4800d4e512be888edea4f9ebbb70407f 260 Gene3D G3DSA:3.40.50.720 44 205 7.3E-4 T 28-03-2018 SMD44_RS21145 17be13dfa9771aa6e2b183a2d8f995d6 161 Pfam PF05258 Protein of unknown function (DUF721) 46 135 4.5E-25 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 SMD44_RS27510 d0370c80e0c09519270527eae74b6364 222 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 108 177 6.8E-9 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF SMD44_RS27510 d0370c80e0c09519270527eae74b6364 222 Pfam PF08044 Domain of unknown function (DUF1707) 18 70 3.7E-20 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 SMD44_RS22210 3e7747b3857f0ebff4b8ce03d6d1d9e2 125 Pfam PF12680 SnoaL-like domain 11 114 1.4E-15 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMD44_RS22210 3e7747b3857f0ebff4b8ce03d6d1d9e2 125 Gene3D G3DSA:3.10.450.50 3 122 6.3E-22 T 28-03-2018 SMD44_RS22210 3e7747b3857f0ebff4b8ce03d6d1d9e2 125 SUPERFAMILY SSF54427 8 120 3.35E-34 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS12875 5da2802afce69348a11e70caba14473e 465 Gene3D G3DSA:3.30.559.10 7 200 5.8E-18 T 28-03-2018 SMD44_RS12875 5da2802afce69348a11e70caba14473e 465 SUPERFAMILY SSF52777 41 181 3.34E-10 T 28-03-2018 SMD44_RS29060 40e11b25b745b26f00ace30c4ba6fe37 275 Pfam PF01987 Mitochondrial biogenesis AIM24 29 210 1.1E-9 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS29060 40e11b25b745b26f00ace30c4ba6fe37 275 SUPERFAMILY SSF51219 16 212 2.88E-28 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD44_RS29060 40e11b25b745b26f00ace30c4ba6fe37 275 Gene3D G3DSA:3.60.160.10 21 229 6.2E-31 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMD44_RS32795 c44aa2269817f40c290ee48233f9f9c4 178 Gene3D G3DSA:3.40.630.30 1 177 5.3E-24 T 28-03-2018 SMD44_RS32795 c44aa2269817f40c290ee48233f9f9c4 178 SUPERFAMILY SSF55729 6 157 1.1E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS32795 c44aa2269817f40c290ee48233f9f9c4 178 Pfam PF13302 Acetyltransferase (GNAT) domain 14 153 6.6E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS39420 fc7a70627449000d4f9b91c1eae4ab1f 205 Gene3D G3DSA:2.30.110.10 1 203 2.3E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS39420 fc7a70627449000d4f9b91c1eae4ab1f 205 Pfam PF04299 Putative FMN-binding domain 5 158 5.6E-19 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type SMD44_RS39420 fc7a70627449000d4f9b91c1eae4ab1f 205 SUPERFAMILY SSF50475 10 179 1.33E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS09455 a5b4622fda2137fda716dba3f4a3425d 240 Pfam PF01988 VIT family 25 232 2.9E-57 T 28-03-2018 IPR008217 Ccc1 family SMD44_RS21660 94defd8832e0487ff543a2bc258165e2 109 Gene3D G3DSA:3.40.250.10 6 105 2.1E-25 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS21660 94defd8832e0487ff543a2bc258165e2 109 SUPERFAMILY SSF52821 9 103 1.15E-27 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS21660 94defd8832e0487ff543a2bc258165e2 109 Pfam PF00581 Rhodanese-like domain 12 93 8.8E-13 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS21660 94defd8832e0487ff543a2bc258165e2 109 SMART SM00450 1 97 2.1E-15 T 28-03-2018 IPR001763 Rhodanese-like domain SMD44_RS42850 8ad1689bd46438a1397a1a7757058e3e 137 Pfam PF05331 Protein of unknown function (DUF742) 30 137 1.6E-26 T 28-03-2018 IPR007995 Protein of unknown function DUF742 SMD44_RS34675 45708292781e08a2c74e352167e34f51 253 Pfam PF01925 Sulfite exporter TauE/SafE 8 247 3.4E-25 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMD44_RS17330 8c60e944ffe46c2d4e97488ebd776591 107 Pfam PF09723 Zinc ribbon domain 2 40 5.8E-13 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD44_RS17330 8c60e944ffe46c2d4e97488ebd776591 107 SMART SM00834 2 41 6.1E-13 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD44_RS17330 8c60e944ffe46c2d4e97488ebd776591 107 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 7.8E-19 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD44_RS27360 496e16266faf5794cac4596b915c396c 315 Pfam PF00482 Type II secretion system (T2SS), protein F 148 268 7.2E-15 T 28-03-2018 IPR018076 Type II secretion system F domain SMD44_RS08970 2a4152bbacad02018fa7b6db08405da9 71 Pfam PF11720 Peptidase inhibitor I78 family 17 62 7.4E-7 T 28-03-2018 IPR021719 Proteinase inhibitor I78 SMD44_RS12220 3fe2e5577d50160e27e1dd51981b7cab 266 Pfam PF03883 Peroxide stress protein YaaA 2 235 1.7E-38 T 28-03-2018 IPR005583 Peroxide stress protein YaaA SMD44_RS41300 6486c7eba60e8586a4d9a7575c453de5 384 Gene3D G3DSA:3.30.470.20 94 378 7.3E-19 T 28-03-2018 SMD44_RS41300 6486c7eba60e8586a4d9a7575c453de5 384 SUPERFAMILY SSF56059 117 303 5.3E-18 T 28-03-2018 SMD44_RS26370 8d9915c1b8f2773283110245c1f2fcb3 92 Gene3D G3DSA:3.30.70.1060 1 91 2.1E-14 T 28-03-2018 SMD44_RS26370 8d9915c1b8f2773283110245c1f2fcb3 92 Pfam PF03795 YCII-related domain 10 83 4.8E-9 T 28-03-2018 IPR005545 YCII-related SMD44_RS26370 8d9915c1b8f2773283110245c1f2fcb3 92 SUPERFAMILY SSF54909 5 84 9.12E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS00045 53c2f651504c9c7ca800f2b8d2780870 76 SUPERFAMILY SSF54913 6 73 5.19E-16 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMD44_RS00045 53c2f651504c9c7ca800f2b8d2780870 76 Pfam PF03091 CutA1 divalent ion tolerance protein 9 73 6.3E-15 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 SMD44_RS00045 53c2f651504c9c7ca800f2b8d2780870 76 Gene3D G3DSA:3.30.70.120 1 75 1.7E-15 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMD44_RS18540 65210f188f48f91c0441eb9e8ee199f5 97 Pfam PF10745 Protein of unknown function (DUF2530) 14 82 1.1E-8 T 28-03-2018 IPR019681 Protein of unknown function DUF2530 SMD44_RS24430 b523774a622632cbac58dac45ce6b396 97 Pfam PF14012 Protein of unknown function (DUF4229) 2 72 2.0E-23 T 28-03-2018 IPR025323 Protein of unknown function DUF4229 SMD44_RS18090 06d4570793098baf147701749d928e66 297 Gene3D G3DSA:1.20.140.10 163 282 1.7E-27 T 28-03-2018 SMD44_RS18090 06d4570793098baf147701749d928e66 297 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 171 283 4.9E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS18090 06d4570793098baf147701749d928e66 297 Gene3D G3DSA:1.10.540.10 1 107 2.5E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS18090 06d4570793098baf147701749d928e66 297 SUPERFAMILY SSF56645 2 90 1.57E-15 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD44_RS18090 06d4570793098baf147701749d928e66 297 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 86 1.8E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMD44_RS18090 06d4570793098baf147701749d928e66 297 SUPERFAMILY SSF47203 167 285 4.67E-27 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD44_RS42230 1f7b2b0fceea645932b9a0cf78fe03f7 319 Pfam PF00487 Fatty acid desaturase 56 299 2.4E-35 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SMD44_RS19420 9bdc86c919331fcd1b7161a303439b96 274 SUPERFAMILY SSF89392 73 258 1.37E-8 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD44_RS06350 10949b77cec88d50262f053bde10ca33 235 Pfam PF09335 SNARE associated Golgi protein 79 196 2.4E-24 T 28-03-2018 IPR032816 SNARE associated Golgi protein SMD44_RS12525 4867ecc4c488c90b777d3523cd399427 215 Pfam PF07510 Protein of unknown function (DUF1524) 113 209 2.1E-9 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 SMD44_RS26710 fab735cacb6c9e3a481cda5d5abf2e74 65 Gene3D G3DSA:3.40.1800.10 2 65 4.2E-10 T 28-03-2018 SMD44_RS26710 fab735cacb6c9e3a481cda5d5abf2e74 65 Pfam PF01844 HNH endonuclease 18 65 6.0E-7 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMD44_RS13055 a76cd556a623408adecd9c844216e666 255 Gene3D G3DSA:3.40.50.150 34 229 1.8E-17 T 28-03-2018 SMD44_RS13055 a76cd556a623408adecd9c844216e666 255 SUPERFAMILY SSF53335 37 219 1.06E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS05140 49850eccb8a309d513ba455f829e18a5 527 Pfam PF03611 PTS system sugar-specific permease component 14 427 3.2E-130 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 SMD44_RS10700 3ed90908ed6b0e78c2f8d575240c1e49 436 Pfam PF01547 Bacterial extracellular solute-binding protein 55 342 2.7E-40 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS10700 3ed90908ed6b0e78c2f8d575240c1e49 436 Gene3D G3DSA:3.40.190.10 175 436 1.6E-46 T 28-03-2018 SMD44_RS10700 3ed90908ed6b0e78c2f8d575240c1e49 436 SUPERFAMILY SSF53850 20 433 2.37E-83 T 28-03-2018 SMD44_RS10700 3ed90908ed6b0e78c2f8d575240c1e49 436 Gene3D G3DSA:3.40.190.10 42 174 3.4E-28 T 28-03-2018 SMD44_RS07670 caaa81fd4aea92b504ce86da5ebf7231 216 Gene3D G3DSA:3.40.630.30 9 201 4.8E-36 T 28-03-2018 SMD44_RS07670 caaa81fd4aea92b504ce86da5ebf7231 216 Pfam PF13302 Acetyltransferase (GNAT) domain 16 156 2.0E-26 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS07670 caaa81fd4aea92b504ce86da5ebf7231 216 SUPERFAMILY SSF55729 10 167 2.13E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS24680 b4d7f5ab4ecf784aa116ccfc691354bd 338 Pfam PF00482 Type II secretion system (T2SS), protein F 120 242 7.3E-10 T 28-03-2018 IPR018076 Type II secretion system F domain SMD44_RS05450 174721a84896d33d32fadeea0f8c18f5 179 Pfam PF13302 Acetyltransferase (GNAT) domain 17 160 9.1E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS05450 174721a84896d33d32fadeea0f8c18f5 179 SUPERFAMILY SSF55729 12 167 1.23E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS05450 174721a84896d33d32fadeea0f8c18f5 179 Gene3D G3DSA:3.40.630.30 2 174 6.3E-23 T 28-03-2018 SMD44_RS28220 95c694dc3f499d033362277cbc0c60d6 132 SMART SM00116 75 122 1.2E-8 T 28-03-2018 IPR000644 CBS domain SMD44_RS28220 95c694dc3f499d033362277cbc0c60d6 132 SMART SM00116 10 58 0.0038 T 28-03-2018 IPR000644 CBS domain SMD44_RS28220 95c694dc3f499d033362277cbc0c60d6 132 Pfam PF00571 CBS domain 73 120 1.8E-12 T 28-03-2018 IPR000644 CBS domain SMD44_RS28220 95c694dc3f499d033362277cbc0c60d6 132 Pfam PF00571 CBS domain 3 54 1.9E-7 T 28-03-2018 IPR000644 CBS domain SMD44_RS28220 95c694dc3f499d033362277cbc0c60d6 132 Gene3D G3DSA:3.10.580.10 1 129 3.9E-24 T 28-03-2018 SMD44_RS28220 95c694dc3f499d033362277cbc0c60d6 132 SUPERFAMILY SSF54631 1 122 1.77E-29 T 28-03-2018 SMD44_RS11490 8af6534dc13bb7f68a0c08b16e4f12df 369 SUPERFAMILY SSF53335 131 301 9.41E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS11490 8af6534dc13bb7f68a0c08b16e4f12df 369 Gene3D G3DSA:3.40.50.150 93 305 1.0E-17 T 28-03-2018 SMD44_RS11490 8af6534dc13bb7f68a0c08b16e4f12df 369 Pfam PF13489 Methyltransferase domain 129 281 2.3E-18 T 28-03-2018 SMD44_RS04835 b22f15cf2efc59049afa1f3b749f8861 432 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 187 296 3.7E-8 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMD44_RS04835 b22f15cf2efc59049afa1f3b749f8861 432 Gene3D G3DSA:3.20.20.360 71 383 7.9E-39 T 28-03-2018 SMD44_RS04835 b22f15cf2efc59049afa1f3b749f8861 432 SUPERFAMILY SSF51621 100 345 8.63E-14 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS17195 98a24b243df0c93fab4272620430158b 764 SUPERFAMILY SSF82866 144 334 3.14E-30 T 28-03-2018 SMD44_RS17195 98a24b243df0c93fab4272620430158b 764 Pfam PF03176 MMPL family 45 398 1.0E-83 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS17195 98a24b243df0c93fab4272620430158b 764 Pfam PF03176 MMPL family 484 728 5.1E-37 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMD44_RS17195 98a24b243df0c93fab4272620430158b 764 SUPERFAMILY SSF82866 489 727 1.31E-29 T 28-03-2018 SMD44_RS17195 98a24b243df0c93fab4272620430158b 764 Gene3D G3DSA:1.20.1640.10 89 342 9.5E-34 T 28-03-2018 SMD44_RS17195 98a24b243df0c93fab4272620430158b 764 Gene3D G3DSA:1.20.1640.10 498 726 3.2E-33 T 28-03-2018 SMD44_RS05445 70996be30f05624c3915f07cbc234292 153 Gene3D G3DSA:2.30.110.10 12 149 7.1E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS05445 70996be30f05624c3915f07cbc234292 153 Pfam PF04075 F420H(2)-dependent quinone reductase 19 148 2.3E-46 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD44_RS05445 70996be30f05624c3915f07cbc234292 153 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 37 147 3.3E-33 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD44_RS07710 553665b006419c9cf4fbc0996cd8ad0f 167 SUPERFAMILY SSF55729 2 148 2.09E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS07710 553665b006419c9cf4fbc0996cd8ad0f 167 Pfam PF00583 Acetyltransferase (GNAT) family 42 137 1.2E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS07710 553665b006419c9cf4fbc0996cd8ad0f 167 Gene3D G3DSA:3.40.630.30 2 146 4.3E-25 T 28-03-2018 SMD44_RS09195 f715d3cdacab0a3ca6aaba051f74239b 347 Pfam PF01032 FecCD transport family 34 341 1.3E-85 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS09195 f715d3cdacab0a3ca6aaba051f74239b 347 Gene3D G3DSA:1.10.3470.10 20 347 4.9E-66 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS09195 f715d3cdacab0a3ca6aaba051f74239b 347 SUPERFAMILY SSF81345 24 342 1.57E-76 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS36945 2923052f759b5b2c563a35fc2e7793dd 425 Gene3D G3DSA:3.30.565.10 272 397 1.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS36945 2923052f759b5b2c563a35fc2e7793dd 425 Pfam PF07730 Histidine kinase 187 250 1.9E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS36945 2923052f759b5b2c563a35fc2e7793dd 425 SUPERFAMILY SSF55874 277 394 2.01E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS24305 334c043cebbfcb6169d4e42794c4cf5d 293 Gene3D G3DSA:3.40.710.10 4 292 2.8E-40 T 28-03-2018 SMD44_RS24305 334c043cebbfcb6169d4e42794c4cf5d 293 SUPERFAMILY SSF56601 9 285 4.2E-46 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS24305 334c043cebbfcb6169d4e42794c4cf5d 293 Pfam PF13354 Beta-lactamase enzyme family 29 260 1.7E-58 T 28-03-2018 SMD44_RS36585 1754fea863cc54f0fe6a4efc906e6ae2 244 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 3 238 3.1E-45 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 SMD44_RS36585 1754fea863cc54f0fe6a4efc906e6ae2 244 Gene3D G3DSA:3.40.50.2300 65 244 1.5E-18 T 28-03-2018 SMD44_RS36585 1754fea863cc54f0fe6a4efc906e6ae2 244 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 3 242 1.6E-68 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 SMD44_RS04770 8f38c5ba52ca161d9904792f77db6b78 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 299 3.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS04770 8f38c5ba52ca161d9904792f77db6b78 309 SUPERFAMILY SSF161098 25 309 1.59E-69 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS04770 8f38c5ba52ca161d9904792f77db6b78 309 Gene3D G3DSA:1.10.3720.10 22 296 1.6E-44 T 28-03-2018 SMD44_RS19675 8ef4b70a168e79df49ba9408521c2364 404 SUPERFAMILY SSF47413 4 71 9.92E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS19675 8ef4b70a168e79df49ba9408521c2364 404 Gene3D G3DSA:1.10.260.40 2 76 2.7E-13 T 28-03-2018 SMD44_RS19675 8ef4b70a168e79df49ba9408521c2364 404 Pfam PF13560 Helix-turn-helix domain 5 66 5.3E-7 T 28-03-2018 SMD44_RS19675 8ef4b70a168e79df49ba9408521c2364 404 SMART SM00530 9 66 3.5E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS10440 7dd1f6bd70a06e71dc05c5a081547385 509 Pfam PF03606 C4-dicarboxylate anaerobic carrier 21 504 3.8E-106 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 SMD44_RS43200 7ff35b24c8c9f52f841d8ea850d6d12b 415 SUPERFAMILY SSF103473 9 408 1.13E-16 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS43200 7ff35b24c8c9f52f841d8ea850d6d12b 415 Pfam PF05977 Transmembrane secretion effector 6 279 2.0E-10 T 28-03-2018 IPR010290 Transmembrane secretion effector SMD44_RS43200 7ff35b24c8c9f52f841d8ea850d6d12b 415 Gene3D G3DSA:1.20.1250.20 212 411 9.5E-6 T 28-03-2018 SMD44_RS43200 7ff35b24c8c9f52f841d8ea850d6d12b 415 Gene3D G3DSA:1.20.1250.20 1 192 5.6E-9 T 28-03-2018 SMD44_RS19010 a0bfa7561af2171531debebbc32dfcd8 160 Pfam PF02559 CarD-like/TRCF domain 3 111 1.9E-18 T 28-03-2018 IPR003711 CarD-like/TRCF domain SMD44_RS19010 a0bfa7561af2171531debebbc32dfcd8 160 SMART SM01058 2 112 1.2E-32 T 28-03-2018 IPR003711 CarD-like/TRCF domain SMD44_RS19010 a0bfa7561af2171531debebbc32dfcd8 160 SUPERFAMILY SSF141259 2 65 3.66E-15 T 28-03-2018 IPR003711 CarD-like/TRCF domain SMD44_RS19280 fa6d17f067fd48468b2dd05bb0347fe1 250 Pfam PF11209 Protein of unknown function (DUF2993) 22 240 1.2E-28 T 28-03-2018 IPR021373 Protein of unknown function DUF2993 SMD44_RS23985 30b9f265a83f7eb5e3f652776cb08018 332 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 80 324 9.0E-132 T 28-03-2018 SMD44_RS36085 4b5dce974a6574fe89a9262bbe4ad14b 107 Gene3D G3DSA:3.10.450.50 9 104 1.4E-5 T 28-03-2018 SMD44_RS36085 4b5dce974a6574fe89a9262bbe4ad14b 107 SUPERFAMILY SSF54427 1 102 3.09E-7 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS43880 dd5ebb0fd88f80fdba67fe05201651fb 403 Gene3D G3DSA:2.40.50.200 287 393 6.6E-5 T 28-03-2018 SMD44_RS32855 1c898dd6003a7e375f48fb52045f9432 433 Pfam PF01590 GAF domain 116 217 6.6E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 SMD44_RS03590 076b3b474e460a4e2ff19e32d1e5100e 213 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 44 208 6.4E-34 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD44_RS03590 076b3b474e460a4e2ff19e32d1e5100e 213 Gene3D G3DSA:1.10.390.10 41 209 3.5E-36 T 28-03-2018 SMD44_RS03590 076b3b474e460a4e2ff19e32d1e5100e 213 SUPERFAMILY SSF55486 41 208 1.48E-26 T 28-03-2018 SMD44_RS27835 d8e17f93e0e8a7c1ebda71c4022f434c 137 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 50 82 4.3E-9 T 28-03-2018 IPR019933 DivIVA domain SMD44_RS19450 ac5575d44ba714dc6bfb321b95d386b6 64 Pfam PF04149 Domain of unknown function (DUF397) 6 58 1.4E-10 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS14690 5c87e4445d7d9397426c10344d1de129 291 Pfam PF12730 ABC-2 family transporter protein 34 160 4.9E-10 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS36935 803910293d757146d38bd22aba2aa758 405 Pfam PF07730 Histidine kinase 192 255 1.8E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD44_RS36935 803910293d757146d38bd22aba2aa758 405 Gene3D G3DSA:3.30.565.10 277 402 1.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS36935 803910293d757146d38bd22aba2aa758 405 SUPERFAMILY SSF55874 282 399 3.68E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS35300 22c863224d7c328698855f7823d5733a 138 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.3E-32 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD44_RS17960 25aa5c3d900ae60b43dd6e6ae47ceac7 439 Gene3D G3DSA:3.40.710.10 96 439 9.4E-63 T 28-03-2018 SMD44_RS17960 25aa5c3d900ae60b43dd6e6ae47ceac7 439 SUPERFAMILY SSF56601 114 423 2.23E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS17960 25aa5c3d900ae60b43dd6e6ae47ceac7 439 Pfam PF00144 Beta-lactamase 117 400 2.4E-45 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS08425 7330b60fb9329d2a89f8a11edd419d07 193 Gene3D G3DSA:3.30.870.10 31 159 4.2E-4 T 28-03-2018 SMD44_RS03595 542aa33ac430a798547385167df8f83a 580 SUPERFAMILY SSF56112 432 505 3.06E-5 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS20290 7cc31fa16d12cf81a1ec3b1492ffaa0e 152 SUPERFAMILY SSF50475 11 150 4.78E-33 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS20290 7cc31fa16d12cf81a1ec3b1492ffaa0e 152 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 100 8.6E-17 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD44_RS20290 7cc31fa16d12cf81a1ec3b1492ffaa0e 152 Gene3D G3DSA:2.30.110.10 3 139 6.1E-29 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMD44_RS20290 7cc31fa16d12cf81a1ec3b1492ffaa0e 152 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 18 142 3.5E-40 T 28-03-2018 IPR019920 F420-binding domain, putative SMD44_RS06505 43baeb69216e4b9191396793cb0a287d 350 SUPERFAMILY SSF103481 82 180 3.92E-12 T 28-03-2018 SMD44_RS06505 43baeb69216e4b9191396793cb0a287d 350 Pfam PF00892 EamA-like transporter family 192 326 5.4E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS06505 43baeb69216e4b9191396793cb0a287d 350 Pfam PF00892 EamA-like transporter family 52 179 8.2E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS06505 43baeb69216e4b9191396793cb0a287d 350 SUPERFAMILY SSF103481 229 331 1.57E-12 T 28-03-2018 SMD44_RS35135 e4a524281e3227c838ba4093dff5f8c4 365 SUPERFAMILY SSF51412 309 352 3.66E-61 T 28-03-2018 SMD44_RS35135 e4a524281e3227c838ba4093dff5f8c4 365 SUPERFAMILY SSF51412 7 249 3.66E-61 T 28-03-2018 SMD44_RS35135 e4a524281e3227c838ba4093dff5f8c4 365 Gene3D G3DSA:3.20.20.70 1 357 1.4E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS35135 e4a524281e3227c838ba4093dff5f8c4 365 Pfam PF03060 Nitronate monooxygenase 8 341 1.9E-92 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMD44_RS39675 8386bfb6a065e0002338d11215c3b1cf 292 Pfam PF03559 NDP-hexose 2,3-dehydratase 85 288 3.4E-58 T 28-03-2018 IPR005212 NDP-hexose 2,3-dehydratase SMD44_RS39675 8386bfb6a065e0002338d11215c3b1cf 292 Pfam PF03559 NDP-hexose 2,3-dehydratase 6 42 3.5E-8 T 28-03-2018 IPR005212 NDP-hexose 2,3-dehydratase SMD44_RS15815 06ed6827a48365283af1b6593d8fa57d 151 Gene3D G3DSA:1.10.287.1060 35 133 3.5E-9 T 28-03-2018 SMD44_RS35315 6fb9b5e8f20a21c8683678513cf2eaf5 234 Pfam PF04493 Endonuclease V 28 221 7.6E-66 T 28-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 SMD44_RS35315 6fb9b5e8f20a21c8683678513cf2eaf5 234 Hamap MF_00801 Endonuclease V [nfi]. 17 231 33.338 T 28-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 SMD44_RS08440 d5b54a0763521fee0a9f3de663ff033a 404 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 33 384 1.3E-90 T 28-03-2018 IPR010640 Low temperature requirement A SMD44_RS21485 dded8a478fe81a27a1de017dc5b3a251 569 Gene3D G3DSA:3.40.50.20 34 284 1.3E-4 T 28-03-2018 SMD44_RS21485 dded8a478fe81a27a1de017dc5b3a251 569 SUPERFAMILY SSF56059 265 482 7.95E-24 T 28-03-2018 SMD44_RS21485 dded8a478fe81a27a1de017dc5b3a251 569 Gene3D G3DSA:3.30.470.20 285 541 1.5E-21 T 28-03-2018 SMD44_RS32045 bbb57ac0b0e308af71efaf88a1dafef2 274 SUPERFAMILY SSF53807 44 123 1.42E-9 T 28-03-2018 SMD44_RS32045 bbb57ac0b0e308af71efaf88a1dafef2 274 Gene3D G3DSA:3.40.50.1980 132 271 7.7E-6 T 28-03-2018 SMD44_RS32045 bbb57ac0b0e308af71efaf88a1dafef2 274 Gene3D G3DSA:3.40.50.1980 34 131 2.8E-9 T 28-03-2018 SMD44_RS21200 72db1a1d2e6b8ab1b507e40dc9c52f66 182 SUPERFAMILY SSF47413 22 64 3.56E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS21200 72db1a1d2e6b8ab1b507e40dc9c52f66 182 Gene3D G3DSA:1.10.260.40 13 178 3.7E-7 T 28-03-2018 SMD44_RS42605 9f39181d19192c3a1f7c315cb186c1cc 279 Gene3D G3DSA:1.10.260.40 1 104 5.0E-7 T 28-03-2018 SMD44_RS01705 af81ef10b4dfe5c2ecc256f9855f1271 180 SUPERFAMILY SSF52833 69 164 1.38E-9 T 28-03-2018 IPR012336 Thioredoxin-like fold SMD44_RS01705 af81ef10b4dfe5c2ecc256f9855f1271 180 Gene3D G3DSA:3.40.30.10 42 175 1.2E-10 T 28-03-2018 SMD44_RS33720 11c0d0e68ee8630ccd073a57bac0a4d8 57 Gene3D G3DSA:1.10.1470.10 4 56 1.6E-7 T 28-03-2018 IPR008462 CsbD-like domain SMD44_RS33720 11c0d0e68ee8630ccd073a57bac0a4d8 57 SUPERFAMILY SSF69047 7 52 6.67E-5 T 28-03-2018 IPR008462 CsbD-like domain SMD44_RS04625 d75740f2ff4d5fe2d4b49be02d1d6955 147 Gene3D G3DSA:3.40.50.300 3 16 0.036 T 28-03-2018 SMD44_RS04625 d75740f2ff4d5fe2d4b49be02d1d6955 147 SUPERFAMILY SSF52540 4 122 1.42E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS04625 d75740f2ff4d5fe2d4b49be02d1d6955 147 Pfam PF13671 AAA domain 3 115 7.6E-14 T 28-03-2018 SMD44_RS04625 d75740f2ff4d5fe2d4b49be02d1d6955 147 Gene3D G3DSA:3.40.50.300 17 141 5.5E-13 T 28-03-2018 SMD44_RS41690 a0475b70bb0e40ef13735483cac52ca5 367 Pfam PF00005 ABC transporter 111 211 8.2E-14 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS41690 a0475b70bb0e40ef13735483cac52ca5 367 SUPERFAMILY SSF52540 86 227 7.03E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS41690 a0475b70bb0e40ef13735483cac52ca5 367 Gene3D G3DSA:3.40.50.300 89 243 1.2E-25 T 28-03-2018 SMD44_RS41690 a0475b70bb0e40ef13735483cac52ca5 367 SUPERFAMILY SSF90123 5 74 4.58E-5 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD44_RS39340 ae5355d1ea22e87f3f578a00e5cacb63 301 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 42 247 6.0E-17 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 SMD44_RS26920 4e401f0dc7271a6aec0e59b08c8a2a2b 402 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 110 241 1.4E-6 T 28-03-2018 SMD44_RS30370 1ee259f06f900d968848f79e60b2b980 137 SUPERFAMILY SSF46785 20 131 7.53E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS30370 1ee259f06f900d968848f79e60b2b980 137 Pfam PF01638 HxlR-like helix-turn-helix 35 120 2.4E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS30370 1ee259f06f900d968848f79e60b2b980 137 Gene3D G3DSA:1.10.10.10 32 133 2.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS16590 69550b2922b5568b0b0dfbe4e9d405cd 306 Gene3D G3DSA:2.60.290.11 32 185 1.0E-8 T 28-03-2018 SMD44_RS17365 e52989bc93832d1f588c5204d953ce12 404 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 36 388 1.1E-95 T 28-03-2018 IPR010640 Low temperature requirement A SMD44_RS37905 f8aa822ad3ac3e2b9656770311e14640 199 Pfam PF04978 Protein of unknown function (DUF664) 10 163 2.8E-46 T 28-03-2018 IPR007061 Protein of unknown function DUF664 SMD44_RS37905 f8aa822ad3ac3e2b9656770311e14640 199 Gene3D G3DSA:1.20.120.450 3 164 4.8E-31 T 28-03-2018 SMD44_RS37905 f8aa822ad3ac3e2b9656770311e14640 199 SUPERFAMILY SSF109854 5 162 8.24E-39 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMD44_RS06405 0d793dde8142ab4faa1f8a77c7553c79 499 SUPERFAMILY SSF103473 25 229 2.62E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS06405 0d793dde8142ab4faa1f8a77c7553c79 499 SUPERFAMILY SSF103473 298 495 2.62E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS06405 0d793dde8142ab4faa1f8a77c7553c79 499 Gene3D G3DSA:1.20.1250.20 297 499 2.6E-12 T 28-03-2018 SMD44_RS06405 0d793dde8142ab4faa1f8a77c7553c79 499 Gene3D G3DSA:1.20.1250.20 38 233 1.7E-31 T 28-03-2018 SMD44_RS06405 0d793dde8142ab4faa1f8a77c7553c79 499 Pfam PF07690 Major Facilitator Superfamily 52 450 1.3E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS00650 26585dd69c6a5354f4b66c446c105eda 169 Gene3D G3DSA:1.10.10.10 97 169 1.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS04995 553090ff600650826a9b806b6e197fc9 226 Gene3D G3DSA:2.130.10.10 5 197 3.3E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS24270 420d31787e8d000c2fd86f9ede46a81b 397 SUPERFAMILY SSF103365 11 397 1.96E-129 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 SMD44_RS24270 420d31787e8d000c2fd86f9ede46a81b 397 Pfam PF01139 tRNA-splicing ligase RtcB 29 397 1.5E-128 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 SMD44_RS27195 555e62c11c0e151c5acf6244d25b63c7 240 Pfam PF03006 Haemolysin-III related 32 229 5.6E-44 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 SMD44_RS02050 927cfde7a0d5762a91b244ebbb41528d 322 Pfam PF00294 pfkB family carbohydrate kinase 7 307 1.6E-46 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB SMD44_RS02050 927cfde7a0d5762a91b244ebbb41528d 322 Gene3D G3DSA:3.40.1190.20 5 316 5.9E-57 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS02050 927cfde7a0d5762a91b244ebbb41528d 322 SUPERFAMILY SSF53613 5 309 3.12E-61 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS02050 927cfde7a0d5762a91b244ebbb41528d 322 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 260 273 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD44_RS20605 04afad23c678a0cd1e77bbf20c7e8513 212 Pfam PF13581 Histidine kinase-like ATPase domain 50 169 4.5E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20605 04afad23c678a0cd1e77bbf20c7e8513 212 SUPERFAMILY SSF55874 73 172 3.76E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20605 04afad23c678a0cd1e77bbf20c7e8513 212 Gene3D G3DSA:3.30.565.10 37 189 4.7E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS24685 751d428566cf10d16eedf042425ac32e 305 Pfam PF00482 Type II secretion system (T2SS), protein F 170 295 7.4E-10 T 28-03-2018 IPR018076 Type II secretion system F domain SMD44_RS05150 746e92e783f900590f3708303a93497f 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD44_RS05150 746e92e783f900590f3708303a93497f 264 SUPERFAMILY SSF51735 3 259 1.27E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS05150 746e92e783f900590f3708303a93497f 264 Gene3D G3DSA:3.40.50.720 2 263 1.2E-58 T 28-03-2018 SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.2E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.2E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.2E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 7.2E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.2E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.2E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS05150 746e92e783f900590f3708303a93497f 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 4.7E-44 T 28-03-2018 SMD44_RS20690 2cafeb584951ec13395c149f809128c5 168 SUPERFAMILY SSF55874 29 150 4.32E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20690 2cafeb584951ec13395c149f809128c5 168 Pfam PF13581 Histidine kinase-like ATPase domain 12 150 2.9E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS20690 2cafeb584951ec13395c149f809128c5 168 Gene3D G3DSA:3.30.565.10 2 162 7.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS27710 f123a6f823803f9da4bb32bd2d487870 192 SUPERFAMILY SSF52980 23 158 2.57E-17 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD44_RS27710 f123a6f823803f9da4bb32bd2d487870 192 Pfam PF05685 Putative restriction endonuclease 22 173 1.7E-22 T 28-03-2018 IPR008538 Domain of unknown function DUF820 SMD44_RS27710 f123a6f823803f9da4bb32bd2d487870 192 Gene3D G3DSA:3.90.1570.10 6 183 6.6E-28 T 28-03-2018 SMD44_RS22170 13dffa47e9f8b884e8bc33040bdd6ec9 143 SUPERFAMILY SSF49764 18 134 2.88E-30 T 28-03-2018 IPR008978 HSP20-like chaperone SMD44_RS22170 13dffa47e9f8b884e8bc33040bdd6ec9 143 Gene3D G3DSA:2.60.40.790 2 136 2.3E-28 T 28-03-2018 IPR008978 HSP20-like chaperone SMD44_RS22170 13dffa47e9f8b884e8bc33040bdd6ec9 143 Pfam PF00011 Hsp20/alpha crystallin family 35 132 6.0E-21 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain SMD44_RS27460 24e3bab5fd1619474c0ebfdada16a748 228 SUPERFAMILY SSF52540 7 223 4.46E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS27460 24e3bab5fd1619474c0ebfdada16a748 228 Pfam PF00005 ABC transporter 23 171 3.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD44_RS27460 24e3bab5fd1619474c0ebfdada16a748 228 Gene3D G3DSA:3.40.50.300 4 226 3.0E-60 T 28-03-2018 SMD44_RS27460 24e3bab5fd1619474c0ebfdada16a748 228 SMART SM00382 32 220 3.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain SMD44_RS25920 35d827320be805d5b62b0b37a9e04c84 175 Pfam PF07681 DoxX 27 129 2.1E-20 T 28-03-2018 IPR032808 DoxX family SMD44_RS42965 32eb17ab048908785b7bec016b3d182c 571 SUPERFAMILY SSF52540 216 354 5.31E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS42965 32eb17ab048908785b7bec016b3d182c 571 Gene3D G3DSA:3.40.50.300 216 563 4.6E-12 T 28-03-2018 SMD44_RS26990 92645aca82bbe5bc8757012c15e2b7d6 291 Pfam PF02237 Biotin protein ligase C terminal domain 237 284 1.9E-11 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 SMD44_RS26990 92645aca82bbe5bc8757012c15e2b7d6 291 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 171 1.6E-9 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SMD44_RS26990 92645aca82bbe5bc8757012c15e2b7d6 291 SUPERFAMILY SSF50037 241 284 6.41E-5 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal SMD44_RS26990 92645aca82bbe5bc8757012c15e2b7d6 291 Gene3D G3DSA:2.30.30.100 237 286 1.7E-17 T 28-03-2018 SMD44_RS26990 92645aca82bbe5bc8757012c15e2b7d6 291 SUPERFAMILY SSF55681 32 227 5.63E-42 T 28-03-2018 SMD44_RS26990 92645aca82bbe5bc8757012c15e2b7d6 291 Gene3D G3DSA:3.30.930.10 8 236 3.0E-63 T 28-03-2018 SMD44_RS26990 92645aca82bbe5bc8757012c15e2b7d6 291 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 43 284 4.9E-40 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 SMD44_RS33195 ad3b29a5bd23aeda1f2b71e1e7bf22c6 195 Pfam PF11188 Protein of unknown function (DUF2975) 90 195 2.3E-11 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 SMD44_RS41735 1c76cc23dbd3d25b375588967812d1f9 190 Gene3D G3DSA:1.10.260.40 24 169 8.0E-4 T 28-03-2018 SMD44_RS28370 1670f4bc785b840dc74f3e9c2f703bbf 500 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 45 333 1.8E-75 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS28370 1670f4bc785b840dc74f3e9c2f703bbf 500 Gene3D G3DSA:3.20.20.300 20 367 1.9E-85 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD44_RS28370 1670f4bc785b840dc74f3e9c2f703bbf 500 SUPERFAMILY SSF51445 27 336 4.21E-81 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS33765 f6987e74f5feae31bb117c2887462fdf 382 Pfam PF06724 Domain of Unknown Function (DUF1206) 136 202 9.1E-22 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 SMD44_RS33765 f6987e74f5feae31bb117c2887462fdf 382 Pfam PF06724 Domain of Unknown Function (DUF1206) 219 286 8.4E-11 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 SMD44_RS33765 f6987e74f5feae31bb117c2887462fdf 382 Pfam PF06724 Domain of Unknown Function (DUF1206) 311 380 3.9E-15 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 SMD44_RS18195 6d788dfcf22d540c681cc2c4ba3a7e97 69 Pfam PF04149 Domain of unknown function (DUF397) 10 65 7.9E-19 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS28235 4184f527e59fcfde605cd469a557e7fc 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.9E-24 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMD44_RS28235 4184f527e59fcfde605cd469a557e7fc 107 SUPERFAMILY SSF103481 6 105 1.01E-17 T 28-03-2018 SMD44_RS10915 9917142e4ffb3780c6556a68e96ab51f 447 Gene3D G3DSA:1.10.510.10 2 154 3.1E-9 T 28-03-2018 SMD44_RS10915 9917142e4ffb3780c6556a68e96ab51f 447 SUPERFAMILY SSF56112 38 149 8.33E-8 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS10915 9917142e4ffb3780c6556a68e96ab51f 447 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 30 432 7.2E-121 T 28-03-2018 IPR018721 Protein of unknown function DUF2252 SMD44_RS23435 fed0a9e8d02304141d7be91616ff1602 73 Pfam PF04149 Domain of unknown function (DUF397) 19 73 6.7E-23 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS02875 c3394604178c301eab4540c9e5b06b34 373 Gene3D G3DSA:3.20.20.30 1 346 1.7E-65 T 28-03-2018 SMD44_RS02875 c3394604178c301eab4540c9e5b06b34 373 SUPERFAMILY SSF51679 11 343 2.22E-63 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS02875 c3394604178c301eab4540c9e5b06b34 373 Pfam PF00296 Luciferase-like monooxygenase 6 319 9.1E-79 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD44_RS17515 f3378d8aa2e802cf0e637ec873b1d68c 374 Pfam PF00144 Beta-lactamase 36 355 1.1E-63 T 28-03-2018 IPR001466 Beta-lactamase-related SMD44_RS17515 f3378d8aa2e802cf0e637ec873b1d68c 374 SUPERFAMILY SSF56601 25 363 2.17E-75 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMD44_RS17515 f3378d8aa2e802cf0e637ec873b1d68c 374 Gene3D G3DSA:3.40.710.10 11 374 6.7E-78 T 28-03-2018 SMD44_RS01045 54d2ed0eba6db87f717813f93c991b57 472 SUPERFAMILY SSF47413 5 67 3.38E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS01045 54d2ed0eba6db87f717813f93c991b57 472 Gene3D G3DSA:1.10.260.40 1 72 1.2E-15 T 28-03-2018 SMD44_RS01045 54d2ed0eba6db87f717813f93c991b57 472 PIRSF PIRSF019251 1 467 6.5E-197 T 28-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 SMD44_RS01045 54d2ed0eba6db87f717813f93c991b57 472 Pfam PF06114 IrrE N-terminal-like domain 194 305 5.8E-18 T 28-03-2018 IPR010359 IrrE N-terminal-like domain SMD44_RS01045 54d2ed0eba6db87f717813f93c991b57 472 Pfam PF13560 Helix-turn-helix domain 7 61 4.0E-12 T 28-03-2018 SMD44_RS01045 54d2ed0eba6db87f717813f93c991b57 472 SMART SM00530 9 64 5.1E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS01045 54d2ed0eba6db87f717813f93c991b57 472 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 306 462 4.8E-72 T 28-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator SMD44_RS43330 6bee3109dae52259b3934a1a63ba3b81 320 SUPERFAMILY SSF56235 10 252 4.29E-23 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS43330 6bee3109dae52259b3934a1a63ba3b81 320 Gene3D G3DSA:3.60.20.10 10 299 2.2E-27 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMD44_RS43330 6bee3109dae52259b3934a1a63ba3b81 320 Pfam PF13522 Glutamine amidotransferase domain 96 219 2.1E-19 T 28-03-2018 SMD44_RS38610 47a471852fbb1d750459178e699bd952 221 Gene3D G3DSA:2.40.10.10 71 167 5.4E-5 T 28-03-2018 SMD44_RS38610 47a471852fbb1d750459178e699bd952 221 SUPERFAMILY SSF50494 53 171 8.35E-5 T 28-03-2018 IPR009003 Peptidase S1, PA clan SMD44_RS28165 35296f747433f08d67e060cc381ceb7f 366 Pfam PF01370 NAD dependent epimerase/dehydratase family 22 230 5.0E-17 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS28165 35296f747433f08d67e060cc381ceb7f 366 Gene3D G3DSA:3.40.50.720 15 323 3.9E-32 T 28-03-2018 SMD44_RS28165 35296f747433f08d67e060cc381ceb7f 366 SUPERFAMILY SSF51735 16 320 3.61E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS40985 59b45ac189b0768acc7c7fbb7123a534 310 Pfam PF01636 Phosphotransferase enzyme family 6 256 5.8E-10 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase SMD44_RS40985 59b45ac189b0768acc7c7fbb7123a534 310 Gene3D G3DSA:3.30.200.20 1 94 0.0023 T 28-03-2018 SMD44_RS40985 59b45ac189b0768acc7c7fbb7123a534 310 Gene3D G3DSA:3.90.1200.10 105 303 9.8E-14 T 28-03-2018 SMD44_RS40985 59b45ac189b0768acc7c7fbb7123a534 310 SUPERFAMILY SSF56112 7 269 8.6E-22 T 28-03-2018 IPR011009 Protein kinase-like domain SMD44_RS15135 496b44a444f226af663e14a254f88243 221 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 24 159 4.6E-6 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD44_RS33875 978a356d329529bbbce15c27b8cac01d 152 Pfam PF11066 Protein of unknown function (DUF2867) 7 140 6.2E-21 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 SMD44_RS22885 730945624fdc495a5d8c7a00bbf59834 136 Pfam PF01042 Endoribonuclease L-PSP 27 132 1.5E-26 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS22885 730945624fdc495a5d8c7a00bbf59834 136 SUPERFAMILY SSF55298 10 135 1.73E-34 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS22885 730945624fdc495a5d8c7a00bbf59834 136 Gene3D G3DSA:3.30.1330.40 7 136 7.7E-34 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS26535 33732796f426f9f3b3eb323a06d67a72 112 SUPERFAMILY SSF51182 23 108 2.18E-6 T 28-03-2018 IPR011051 RmlC-like cupin domain SMD44_RS26535 33732796f426f9f3b3eb323a06d67a72 112 Gene3D G3DSA:2.60.120.10 5 112 7.5E-6 T 28-03-2018 IPR014710 RmlC-like jelly roll fold SMD44_RS30920 11790fc606f71300a62ebaf135c72e67 356 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 148 355 1.3E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS30920 11790fc606f71300a62ebaf135c72e67 356 Gene3D G3DSA:1.10.3720.10 32 344 3.2E-35 T 28-03-2018 SMD44_RS30920 11790fc606f71300a62ebaf135c72e67 356 SUPERFAMILY SSF161098 126 338 4.03E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS38575 74fba75cf54a433c6eaac235fadb4117 424 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 257 7.0E-90 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMD44_RS38575 74fba75cf54a433c6eaac235fadb4117 424 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 278 401 9.6E-24 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMD44_RS38575 74fba75cf54a433c6eaac235fadb4117 424 PIRSF PIRSF006446 256 418 3.9E-26 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMD44_RS38575 74fba75cf54a433c6eaac235fadb4117 424 PIRSF PIRSF006446 1 268 4.0E-80 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMD44_RS23710 58a40cbfcdcc4d19892cda759b38eb8c 162 Pfam PF11377 Protein of unknown function (DUF3180) 9 149 9.3E-36 T 28-03-2018 IPR021517 Protein of unknown function DUF3180 SMD44_RS23710 58a40cbfcdcc4d19892cda759b38eb8c 162 Gene3D G3DSA:1.20.1640.10 28 159 1.1E-4 T 28-03-2018 SMD44_RS03560 349200e72a57219eafd28c25e90d1bb9 254 Pfam PF06912 Protein of unknown function (DUF1275) 30 228 6.2E-35 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 SMD44_RS02660 ae1621ac181a56ef7bd8e7cf57a07b0c 188 Pfam PF00857 Isochorismatase family 3 178 2.8E-41 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS02660 ae1621ac181a56ef7bd8e7cf57a07b0c 188 SUPERFAMILY SSF52499 2 181 4.32E-53 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD44_RS02660 ae1621ac181a56ef7bd8e7cf57a07b0c 188 Gene3D G3DSA:3.40.50.850 1 186 1.5E-46 T 28-03-2018 SMD44_RS37460 5196f7296a995d082128b8ab6cb61dfa 71 Pfam PF07311 Dodecin 5 68 9.6E-30 T 28-03-2018 IPR009923 Dodecin SMD44_RS37460 5196f7296a995d082128b8ab6cb61dfa 71 Gene3D G3DSA:3.30.1660.10 4 68 1.0E-31 T 28-03-2018 IPR025543 Dodecin-like SMD44_RS37460 5196f7296a995d082128b8ab6cb61dfa 71 SUPERFAMILY SSF89807 3 68 9.29E-26 T 28-03-2018 IPR009923 Dodecin SMD44_RS01215 cb71302b16badb6b4fee720be62ee7be 152 Pfam PF01638 HxlR-like helix-turn-helix 21 104 1.7E-19 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type SMD44_RS01215 cb71302b16badb6b4fee720be62ee7be 152 SUPERFAMILY SSF46785 7 144 3.23E-39 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS01215 cb71302b16badb6b4fee720be62ee7be 152 Gene3D G3DSA:1.10.10.10 2 151 3.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS35680 032aaf7d545e8b566ef9f9aebd28ce2b 455 Gene3D G3DSA:3.40.50.1980 103 180 0.084 T 28-03-2018 SMD44_RS35680 032aaf7d545e8b566ef9f9aebd28ce2b 455 Gene3D G3DSA:3.40.50.1980 284 403 0.011 T 28-03-2018 SMD44_RS17635 aa6c8c3de975eba35cd4deee46cf7630 69 Pfam PF04149 Domain of unknown function (DUF397) 10 62 7.1E-19 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS19585 10a54967805dce50b68530aff6f289a6 484 Gene3D G3DSA:1.25.40.10 230 465 1.0E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS33840 7521f06d20e6f22a84f1c82405541557 383 Pfam PF07786 Protein of unknown function (DUF1624) 3 199 1.4E-9 T 28-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 SMD44_RS33840 7521f06d20e6f22a84f1c82405541557 383 Pfam PF04235 Protein of unknown function (DUF418) 271 376 6.9E-12 T 28-03-2018 IPR007349 Domain of unknown function DUF418 SMD44_RS33080 c9b7c69b34b086efd40f7b1a6107b954 652 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 7 614 1.4E-200 T 28-03-2018 IPR011749 Conserved hypothetical protein CHP02243 SMD44_RS33080 c9b7c69b34b086efd40f7b1a6107b954 652 Pfam PF04865 Baseplate J-like protein 398 572 9.8E-12 T 28-03-2018 IPR006949 Baseplate protein J-like SMD44_RS25990 0db20e5f5f84b5c2d8d8ed048a10b43d 460 Pfam PF04434 SWIM zinc finger 71 91 6.0E-6 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 SMD44_RS16980 82e689f6dc8d8725aeb5030032e2a7db 125 Gene3D G3DSA:3.10.180.10 6 119 6.8E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS16980 82e689f6dc8d8725aeb5030032e2a7db 125 SUPERFAMILY SSF54593 1 120 7.15E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS13685 4134b0c98a293209adb5cb3240d72a67 225 Pfam PF05099 Tellurite resistance protein TerB 87 216 7.0E-10 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal SMD44_RS13685 4134b0c98a293209adb5cb3240d72a67 225 Gene3D G3DSA:1.10.3680.10 75 224 2.1E-20 T 28-03-2018 IPR029024 TerB-like SMD44_RS13685 4134b0c98a293209adb5cb3240d72a67 225 SUPERFAMILY SSF158682 155 220 4.19E-9 T 28-03-2018 SMD44_RS37860 348935fb7e95c87836ccb1c1e2778064 118 SUPERFAMILY SSF54427 11 101 1.18E-5 T 28-03-2018 IPR032710 NTF2-like domain SMD44_RS28995 20eb902c402abd8d9c92df2f0f1de416 299 Gene3D G3DSA:3.10.490.10 72 259 2.0E-4 T 28-03-2018 SMD44_RS22610 51b1bc0c822b49fc109763e2b1e2d118 394 Gene3D G3DSA:3.90.1150.10 277 387 1.5E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS22610 51b1bc0c822b49fc109763e2b1e2d118 394 SUPERFAMILY SSF53383 3 382 1.03E-85 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS22610 51b1bc0c822b49fc109763e2b1e2d118 394 Pfam PF00155 Aminotransferase class I and II 33 378 2.6E-39 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD44_RS22610 51b1bc0c822b49fc109763e2b1e2d118 394 Gene3D G3DSA:3.40.640.10 68 276 3.5E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS03525 e732187384e017f8005375ea56b0f8e0 408 Pfam PF10138 vWA found in TerF C terminus 220 407 1.4E-30 T 28-03-2018 IPR019303 vWA found in TerF C terminus SMD44_RS03525 e732187384e017f8005375ea56b0f8e0 408 Pfam PF02342 TerD domain 6 158 1.2E-22 T 28-03-2018 IPR003325 TerD domain GO:0006950 SMD44_RS03525 e732187384e017f8005375ea56b0f8e0 408 Gene3D G3DSA:2.60.60.30 13 157 4.1E-26 T 28-03-2018 SMD44_RS28605 d02c63e5b0f062d52e652b8a750987ad 234 Gene3D G3DSA:3.40.50.150 43 223 1.4E-18 T 28-03-2018 SMD44_RS28605 d02c63e5b0f062d52e652b8a750987ad 234 SUPERFAMILY SSF53335 12 199 4.57E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38230 630a1f3aa3cdab55920769ebde50a728 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 313 9.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS38230 630a1f3aa3cdab55920769ebde50a728 318 SUPERFAMILY SSF161098 80 305 6.67E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS38230 630a1f3aa3cdab55920769ebde50a728 318 Gene3D G3DSA:1.10.3720.10 41 318 2.7E-49 T 28-03-2018 SMD44_RS32425 eeb6699b726b633a73fd29439efa419f 251 Gene3D G3DSA:1.20.1260.10 45 191 1.4E-12 T 28-03-2018 IPR012347 Ferritin-related SMD44_RS32425 eeb6699b726b633a73fd29439efa419f 251 Pfam PF13628 Domain of unknown function (DUF4142) 57 187 9.5E-18 T 28-03-2018 IPR025419 Domain of unknown function DUF4142 SMD44_RS22460 55baa258d78d1b529ae1badf4e96da93 435 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 334 399 9.0E-11 T 28-03-2018 SMD44_RS22460 55baa258d78d1b529ae1badf4e96da93 435 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 128 202 4.3E-6 T 28-03-2018 SMD44_RS22460 55baa258d78d1b529ae1badf4e96da93 435 Gene3D G3DSA:2.130.10.130 132 269 4.8E-16 T 28-03-2018 SMD44_RS22460 55baa258d78d1b529ae1badf4e96da93 435 Gene3D G3DSA:2.130.10.130 318 433 7.3E-18 T 28-03-2018 SMD44_RS22460 55baa258d78d1b529ae1badf4e96da93 435 Gene3D G3DSA:2.60.40.680 26 131 9.1E-6 T 28-03-2018 SMD44_RS22460 55baa258d78d1b529ae1badf4e96da93 435 SUPERFAMILY SSF69318 61 292 1.22E-34 T 28-03-2018 SMD44_RS22460 55baa258d78d1b529ae1badf4e96da93 435 SUPERFAMILY SSF69318 329 426 1.22E-34 T 28-03-2018 SMD44_RS09555 4fc3bc2062020ee7cca50d7f7f7f9b50 295 SUPERFAMILY SSF55486 89 282 3.02E-7 T 28-03-2018 SMD44_RS09555 4fc3bc2062020ee7cca50d7f7f7f9b50 295 Pfam PF04228 Putative neutral zinc metallopeptidase 10 294 3.4E-82 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative SMD44_RS37160 fe26d0c06d42bd8b6c94556ab5d1633d 138 SUPERFAMILY SSF54593 7 136 9.67E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS37160 fe26d0c06d42bd8b6c94556ab5d1633d 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 4.2E-14 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS37160 fe26d0c06d42bd8b6c94556ab5d1633d 138 Gene3D G3DSA:3.10.180.10 3 138 1.9E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS34185 efb8087ca4082bc45d0b988adb1ff284 327 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 248 2.0E-47 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMD44_RS34185 efb8087ca4082bc45d0b988adb1ff284 327 PIRSF PIRSF015582 1 326 1.9E-94 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like SMD44_RS34185 efb8087ca4082bc45d0b988adb1ff284 327 Gene3D G3DSA:3.20.20.60 2 260 6.5E-61 T 28-03-2018 SMD44_RS34185 efb8087ca4082bc45d0b988adb1ff284 327 SUPERFAMILY SSF51621 14 259 2.3E-65 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS00765 b9e84985c28b62eb1fa109037773eafe 279 Gene3D G3DSA:3.30.460.10 72 214 2.2E-6 T 28-03-2018 SMD44_RS27865 03bb1ab8e0c87b92d5add5513e9d40dc 368 Pfam PF13490 Putative zinc-finger 20 48 7.2E-8 T 28-03-2018 IPR027383 Putative zinc-finger SMD44_RS02585 2159499ea83d229d583fdf1b758603b8 281 SMART SM00530 18 73 1.8E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS02585 2159499ea83d229d583fdf1b758603b8 281 Gene3D G3DSA:1.10.3100.10 11 167 3.1E-13 T 28-03-2018 IPR027910 YdiL-like domain SMD44_RS02585 2159499ea83d229d583fdf1b758603b8 281 SUPERFAMILY SSF47413 14 73 2.47E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS02585 2159499ea83d229d583fdf1b758603b8 281 Pfam PF13560 Helix-turn-helix domain 15 75 5.1E-14 T 28-03-2018 SMD44_RS07020 cf266a547f3fde70a2bd4a325714447e 220 Pfam PF04973 Nicotinamide mononucleotide transporter 21 201 5.6E-41 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SMD44_RS30295 4af2ced95ce1ece177b0fd6b4a4ac76e 77 Gene3D G3DSA:3.30.70.920 1 77 3.1E-16 T 28-03-2018 SMD44_RS30295 4af2ced95ce1ece177b0fd6b4a4ac76e 77 SUPERFAMILY SSF54909 2 75 7.78E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel SMD44_RS30295 4af2ced95ce1ece177b0fd6b4a4ac76e 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 2.4E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD44_RS30585 557bf3aee2000e7f7e70d4dbcbbf0ce2 378 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 332 358 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 SMD44_RS30585 557bf3aee2000e7f7e70d4dbcbbf0ce2 378 Pfam PF01148 Cytidylyltransferase family 119 373 3.3E-63 T 28-03-2018 SMD44_RS43355 32155bd7a4f0be5d205db7dadc61bc9a 377 Pfam PF14386 Domain of unknown function (DUF4417) 165 252 8.0E-11 T 28-03-2018 IPR025530 Protein of unknown function DUF4417 SMD44_RS23145 89fa8be51dd8db88837b7d69b4fefe1d 131 Pfam PF02467 Transcription factor WhiB 24 86 1.4E-24 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS23145 89fa8be51dd8db88837b7d69b4fefe1d 131 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 18 91 18.862 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS26820 97fee7b34cf85409c6f0d881d87b3fde 253 SUPERFAMILY SSF53474 28 219 2.1E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS26820 97fee7b34cf85409c6f0d881d87b3fde 253 Gene3D G3DSA:3.40.50.1820 11 238 1.7E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS40925 9dc5150b99acb63a44443ace83b5635a 255 Pfam PF01738 Dienelactone hydrolase family 20 235 4.8E-26 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SMD44_RS40925 9dc5150b99acb63a44443ace83b5635a 255 SUPERFAMILY SSF53474 4 237 1.84E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS40925 9dc5150b99acb63a44443ace83b5635a 255 Gene3D G3DSA:3.40.50.1820 1 235 2.3E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS41560 526e3fdad6f95a8d39f7a36ccca8d359 412 Pfam PF06224 Winged helix DNA-binding domain 52 393 8.1E-56 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 SMD44_RS41560 526e3fdad6f95a8d39f7a36ccca8d359 412 Gene3D G3DSA:3.30.9.10 125 248 0.011 T 28-03-2018 SMD44_RS26220 483ab09b38d0e9c2d23549b2c3150f17 284 SUPERFAMILY SSF103481 40 119 1.57E-6 T 28-03-2018 SMD44_RS22975 3b99a05f2a7fed103bc4a4b7c7c59221 110 Gene3D G3DSA:1.10.287.1080 6 104 2.6E-5 T 28-03-2018 SMD44_RS22975 3b99a05f2a7fed103bc4a4b7c7c59221 110 SUPERFAMILY SSF101386 11 103 3.79E-8 T 28-03-2018 SMD44_RS40225 690778ad45c5d965c03fb84dcc687ff4 191 Gene3D G3DSA:2.60.120.260 1 189 2.6E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like SMD44_RS21320 cde287c618f70788463f19b4038861e8 79 Pfam PF03777 Small secreted domain (DUF320) 23 78 1.1E-29 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS08555 e02f6d847186a8d75e04932816aec7a7 202 Gene3D G3DSA:2.20.25.10 138 189 0.0017 T 28-03-2018 SMD44_RS05260 f8160711791cd1aee89f26719b0655f2 359 Pfam PF01925 Sulfite exporter TauE/SafE 232 347 1.1E-20 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMD44_RS05260 f8160711791cd1aee89f26719b0655f2 359 Pfam PF01925 Sulfite exporter TauE/SafE 8 168 2.5E-16 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMD44_RS24905 7d3527dfc82a513e4ac6c51874d7d186 415 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 22 398 2.7E-35 T 28-03-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 SMD44_RS24905 7d3527dfc82a513e4ac6c51874d7d186 415 Pfam PF03237 Terminase-like family 27 223 6.2E-8 T 28-03-2018 SMD44_RS43270 9da829d60d021b798ea2045644d3fa63 337 Pfam PF01863 Protein of unknown function DUF45 111 321 4.3E-22 T 28-03-2018 IPR002725 Protein of unknown function DUF45 SMD44_RS24895 e5d7bb02ac96ef525039b342d651f668 470 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 179 455 3.6E-6 T 28-03-2018 IPR021145 Portal protein SMD44_RS11360 8006769ced354e39cc1bcea247c01282 465 Gene3D G3DSA:3.40.640.10 45 291 4.4E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS11360 8006769ced354e39cc1bcea247c01282 465 Gene3D G3DSA:3.90.1150.10 292 434 7.7E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS11360 8006769ced354e39cc1bcea247c01282 465 Pfam PF00266 Aminotransferase class-V 39 427 1.3E-75 T 28-03-2018 IPR000192 Aminotransferase class V domain SMD44_RS11360 8006769ced354e39cc1bcea247c01282 465 SUPERFAMILY SSF53383 36 435 3.16E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS06250 c04af90256b2f15878f1fb2c6129efb0 398 Pfam PF02515 CoA-transferase family III 7 374 1.9E-113 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMD44_RS06250 c04af90256b2f15878f1fb2c6129efb0 398 SUPERFAMILY SSF89796 5 397 6.41E-125 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS06250 c04af90256b2f15878f1fb2c6129efb0 398 Gene3D G3DSA:3.40.50.10540 1 398 1.9E-127 T 28-03-2018 IPR023606 CoA-transferase family III domain SMD44_RS24530 5ca339df32a14227a83a9c3b3cef7ece 401 Gene3D G3DSA:3.60.60.10 133 381 3.6E-29 T 28-03-2018 SMD44_RS24530 5ca339df32a14227a83a9c3b3cef7ece 401 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 147 324 4.2E-13 T 28-03-2018 IPR005079 Peptidase C45 SMD44_RS11085 b03f31cc54fe237c74b8b87647202652 454 Pfam PF01882 Protein of unknown function DUF58 218 296 3.0E-19 T 28-03-2018 IPR002881 Domain of unknown function DUF58 SMD44_RS11085 b03f31cc54fe237c74b8b87647202652 454 Gene3D G3DSA:3.40.50.410 223 301 1.0E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A SMD44_RS33675 ac0cc311c2467e7b5ff607480ae367fd 277 SUPERFAMILY SSF102588 5 276 6.02E-63 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS33675 ac0cc311c2467e7b5ff607480ae367fd 277 Gene3D G3DSA:3.40.50.10320 2 277 2.3E-65 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD44_RS33675 ac0cc311c2467e7b5ff607480ae367fd 277 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 156 7.0E-28 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD44_RS21270 eaf6d4f4e0ef4d85aebaa907c2abb8b3 415 Gene3D G3DSA:3.20.20.80 114 356 1.1E-35 T 28-03-2018 SMD44_RS21270 eaf6d4f4e0ef4d85aebaa907c2abb8b3 415 Pfam PF02156 Glycosyl hydrolase family 26 212 274 2.8E-7 T 28-03-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 SMD44_RS21270 eaf6d4f4e0ef4d85aebaa907c2abb8b3 415 SUPERFAMILY SSF51445 108 338 3.46E-35 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS42715 daf018f98ac517de3f3d6d4ae27cec86 220 SUPERFAMILY SSF53098 13 187 6.84E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS42715 daf018f98ac517de3f3d6d4ae27cec86 220 Gene3D G3DSA:3.30.420.10 11 195 7.8E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMD44_RS42715 daf018f98ac517de3f3d6d4ae27cec86 220 SMART SM00479 14 189 1.0E-14 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS42715 daf018f98ac517de3f3d6d4ae27cec86 220 Pfam PF00929 Exonuclease 16 180 1.4E-14 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD44_RS02065 304bf56dc0449a36ee98505bd7e0755a 443 Gene3D G3DSA:3.40.190.10 44 181 0.0047 T 28-03-2018 SMD44_RS02065 304bf56dc0449a36ee98505bd7e0755a 443 Pfam PF01547 Bacterial extracellular solute-binding protein 67 351 2.5E-37 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMD44_RS02065 304bf56dc0449a36ee98505bd7e0755a 443 SUPERFAMILY SSF53850 50 434 1.04E-68 T 28-03-2018 SMD44_RS02065 304bf56dc0449a36ee98505bd7e0755a 443 Gene3D G3DSA:3.40.190.10 182 439 7.1E-38 T 28-03-2018 SMD44_RS43335 167f8cd56994144437a0b91011634868 544 Pfam PF12224 Putative amidoligase enzyme 247 406 5.4E-7 T 28-03-2018 IPR022025 Putative amidoligase enzyme SMD44_RS01480 d9df86dfad0f0c83182030564a66e1eb 360 Gene3D G3DSA:1.10.3470.10 35 360 2.5E-58 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS01480 d9df86dfad0f0c83182030564a66e1eb 360 Pfam PF01032 FecCD transport family 49 354 4.8E-79 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS01480 d9df86dfad0f0c83182030564a66e1eb 360 SUPERFAMILY SSF81345 39 354 1.57E-67 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS34945 7bb7422c15698de910b37ade5ad0ecb6 748 Gene3D G3DSA:3.40.50.1820 11 328 1.4E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS34945 7bb7422c15698de910b37ade5ad0ecb6 748 SUPERFAMILY SSF53383 349 667 2.92E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS34945 7bb7422c15698de910b37ade5ad0ecb6 748 SUPERFAMILY SSF53383 711 745 2.92E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS34945 7bb7422c15698de910b37ade5ad0ecb6 748 Gene3D G3DSA:3.40.640.10 345 572 4.7E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS34945 7bb7422c15698de910b37ade5ad0ecb6 748 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 351 667 8.1E-76 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD44_RS34945 7bb7422c15698de910b37ade5ad0ecb6 748 SUPERFAMILY SSF53474 60 329 6.51E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold SMD44_RS34945 7bb7422c15698de910b37ade5ad0ecb6 748 Gene3D G3DSA:3.90.1150.10 573 747 3.2E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMD44_RS04665 3931827bde188e96cdf0dbb41610c756 124 Gene3D G3DSA:1.10.10.10 17 124 5.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS21855 43fbfb36b9272bb0c050a84ed760b870 166 Pfam PF04525 LURP-one-related 5 153 1.2E-29 T 28-03-2018 IPR007612 LURP1-related protein domain SMD44_RS21855 43fbfb36b9272bb0c050a84ed760b870 166 SUPERFAMILY SSF54518 1 153 1.52E-30 T 28-03-2018 IPR025659 Tubby C-terminal-like domain SMD44_RS19050 725e8c599f6a6c54cf670fc40a6b4b98 432 Gene3D G3DSA:1.20.1250.20 213 402 9.4E-23 T 28-03-2018 SMD44_RS19050 725e8c599f6a6c54cf670fc40a6b4b98 432 Gene3D G3DSA:1.20.1250.20 18 211 7.4E-34 T 28-03-2018 SMD44_RS19050 725e8c599f6a6c54cf670fc40a6b4b98 432 SUPERFAMILY SSF103473 19 396 2.09E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain SMD44_RS19050 725e8c599f6a6c54cf670fc40a6b4b98 432 Pfam PF07690 Major Facilitator Superfamily 241 400 5.1E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS19050 725e8c599f6a6c54cf670fc40a6b4b98 432 Pfam PF07690 Major Facilitator Superfamily 25 238 8.8E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD44_RS04420 8b9f707f9fbfe6719d216c1dded6bfa0 512 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 12 226 8.7E-13 T 28-03-2018 IPR021145 Portal protein SMD44_RS06305 c9dae28655ad5a8334bcf54289dca7ae 184 Gene3D G3DSA:3.40.190.10 16 175 7.6E-4 T 28-03-2018 SMD44_RS11715 10698d0ba78f9651c9f6dc3599cfa840 351 Pfam PF01032 FecCD transport family 30 346 2.1E-90 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD44_RS11715 10698d0ba78f9651c9f6dc3599cfa840 351 SUPERFAMILY SSF81345 14 346 8.63E-76 T 28-03-2018 IPR029022 ABC transporter, BtuC-like SMD44_RS11715 10698d0ba78f9651c9f6dc3599cfa840 351 Gene3D G3DSA:1.10.3470.10 15 351 3.1E-72 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS26200 3ed39111643558fe0218f803b2cee298 250 Pfam PF13460 NAD(P)H-binding 7 174 1.3E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS26200 3ed39111643558fe0218f803b2cee298 250 SUPERFAMILY SSF51735 1 209 1.27E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS26200 3ed39111643558fe0218f803b2cee298 250 Gene3D G3DSA:3.40.50.720 1 248 6.0E-16 T 28-03-2018 SMD44_RS35870 970c1a008fc01fee650f7e57b9115b2d 146 SUPERFAMILY SSF54060 49 126 8.12E-16 T 28-03-2018 SMD44_RS35870 970c1a008fc01fee650f7e57b9115b2d 146 Gene3D G3DSA:3.40.1800.10 47 117 1.2E-7 T 28-03-2018 SMD44_RS35870 970c1a008fc01fee650f7e57b9115b2d 146 Pfam PF02945 Recombination endonuclease VII 46 124 6.4E-21 T 28-03-2018 IPR004211 Recombination endonuclease VII SMD44_RS09445 dc0d1175111ae3e2e60d84003a505520 212 Pfam PF07947 YhhN family 25 198 3.5E-37 T 28-03-2018 IPR012506 YhhN-like GO:0016021 SMD44_RS23040 19c94fb1b0f38f1a1c5188bf19e995da 322 Pfam PF08007 Cupin superfamily protein 97 279 7.3E-25 T 28-03-2018 IPR003347 JmjC domain SMD44_RS23040 19c94fb1b0f38f1a1c5188bf19e995da 322 SUPERFAMILY SSF51197 85 283 2.2E-27 T 28-03-2018 SMD44_RS23040 19c94fb1b0f38f1a1c5188bf19e995da 322 Gene3D G3DSA:2.60.120.650 13 224 6.6E-19 T 28-03-2018 SMD44_RS32150 b200eec7949dc275ab271fac0354eb2a 185 Gene3D G3DSA:3.30.565.10 49 185 7.9E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS32150 b200eec7949dc275ab271fac0354eb2a 185 SUPERFAMILY SSF55874 78 178 4.88E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS32150 b200eec7949dc275ab271fac0354eb2a 185 Pfam PF13581 Histidine kinase-like ATPase domain 66 178 1.3E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS11695 cd5d8a3fa1cfbe8e923ae28a8d07acd8 199 Gene3D G3DSA:3.40.190.10 4 147 6.7E-4 T 28-03-2018 SMD44_RS08965 7cb45cb32537ef65da19f0609cb4e9f9 336 SMART SM00014 113 229 1.6E-7 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS08965 7cb45cb32537ef65da19f0609cb4e9f9 336 Gene3D G3DSA:1.20.144.10 41 240 1.8E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS08965 7cb45cb32537ef65da19f0609cb4e9f9 336 Pfam PF01569 PAP2 superfamily 117 230 3.3E-18 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS08965 7cb45cb32537ef65da19f0609cb4e9f9 336 SUPERFAMILY SSF48317 34 246 1.31E-28 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD44_RS08910 e5e26c2296b20531e036403978ca8365 267 Pfam PF07920 Protein of unknown function (DUF1684) 124 259 2.0E-34 T 28-03-2018 IPR012467 Protein of unknown function DUF1684 SMD44_RS09745 0e735545d92e05e5286f0a148c0a8b27 208 Pfam PF07081 Protein of unknown function (DUF1349) 27 198 1.5E-41 T 28-03-2018 IPR009784 Protein of unknown function DUF1349 SMD44_RS09745 0e735545d92e05e5286f0a148c0a8b27 208 Gene3D G3DSA:2.60.120.200 18 199 5.3E-27 T 28-03-2018 SMD44_RS09745 0e735545d92e05e5286f0a148c0a8b27 208 SUPERFAMILY SSF49899 57 198 5.14E-16 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMD44_RS42700 15691f41b14d14c7da5ad63c6fa2d490 99 Gene3D G3DSA:3.40.50.450 3 96 2.3E-6 T 28-03-2018 SMD44_RS40510 dda17b510a4efa7bc4ef3f622f3f9b13 460 Pfam PF03929 PepSY-associated TM region 10 389 9.9E-65 T 28-03-2018 IPR005625 PepSY-associated TM protein SMD44_RS34370 e05d6c02aacab362b4e1f9648ea4f3b4 127 Pfam PF00741 Gas vesicle protein 17 55 4.9E-17 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMD44_RS34370 e05d6c02aacab362b4e1f9648ea4f3b4 127 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 18 32 - T 28-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMD44_RS10350 d5bf2ea7c287fb35bbe64d65ae66ec02 236 Pfam PF05988 Bacterial protein of unknown function (DUF899) 3 227 1.5E-84 T 28-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like SMD44_RS10350 d5bf2ea7c287fb35bbe64d65ae66ec02 236 Gene3D G3DSA:3.40.30.10 15 183 6.2E-13 T 28-03-2018 SMD44_RS43780 877fa4e3d52e2ca2023bccc5a1ba92dd 264 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 72 255 1.5E-5 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS43780 877fa4e3d52e2ca2023bccc5a1ba92dd 264 SUPERFAMILY SSF56219 16 263 2.22E-16 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS43780 877fa4e3d52e2ca2023bccc5a1ba92dd 264 Gene3D G3DSA:3.60.10.10 3 264 3.8E-19 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMD44_RS37820 9744eb8f7602212f33e15d213a600f7b 75 Pfam PF17196 Protein of unknown function (DUF5133) 1 64 8.5E-28 T 28-03-2018 IPR033457 Protein of unknown function DUF5133 SMD44_RS11895 3333bb97d470246a0d8a3c22ccccb7a8 284 SUPERFAMILY SSF161098 41 267 3.66E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS11895 3333bb97d470246a0d8a3c22ccccb7a8 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 214 1.8E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS11895 3333bb97d470246a0d8a3c22ccccb7a8 284 Gene3D G3DSA:1.10.3720.10 1 282 1.5E-41 T 28-03-2018 SMD44_RS26560 a218a6b8e879bf6e7725d48145588f29 241 SUPERFAMILY SSF103501 1 222 5.62E-68 T 28-03-2018 IPR023234 NarG-like domain SMD44_RS26560 a218a6b8e879bf6e7725d48145588f29 241 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 3 222 1.1E-62 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 SMD44_RS26560 a218a6b8e879bf6e7725d48145588f29 241 Pfam PF02665 Nitrate reductase gamma subunit 2 222 2.4E-88 T 28-03-2018 IPR023234 NarG-like domain SMD44_RS26560 a218a6b8e879bf6e7725d48145588f29 241 Gene3D G3DSA:1.20.950.20 1 214 2.5E-51 T 28-03-2018 SMD44_RS18380 e74140bd76c5181786a122f633e98b6a 1381 Gene3D G3DSA:1.10.530.10 351 626 2.2E-4 T 28-03-2018 SMD44_RS39000 73810348b2e65e0318525e7e08ae6520 367 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 3 358 7.4E-138 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMD44_RS39000 73810348b2e65e0318525e7e08ae6520 367 Pfam PF01924 Hydrogenase formation hypA family 12 357 2.4E-144 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMD44_RS39000 73810348b2e65e0318525e7e08ae6520 367 PIRSF PIRSF005622 1 363 3.9E-144 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMD44_RS22525 fdedc72cf42cea9d43c8eeb074f88ff1 325 SMART SM00421 257 314 1.0E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22525 fdedc72cf42cea9d43c8eeb074f88ff1 325 Pfam PF00196 Bacterial regulatory proteins, luxR family 261 310 3.2E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22525 fdedc72cf42cea9d43c8eeb074f88ff1 325 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 290 302 2.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22525 fdedc72cf42cea9d43c8eeb074f88ff1 325 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 260 274 2.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22525 fdedc72cf42cea9d43c8eeb074f88ff1 325 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 274 290 2.0E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD44_RS22525 fdedc72cf42cea9d43c8eeb074f88ff1 325 SUPERFAMILY SSF46894 248 320 2.01E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD44_RS22525 fdedc72cf42cea9d43c8eeb074f88ff1 325 Gene3D G3DSA:1.10.10.10 22 324 6.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS19140 d25b5e017471dde8b8929af16596f3d0 198 Gene3D G3DSA:2.130.10.10 31 195 5.5E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS30180 73a300e7fcfa4f44e17735c0e88578f9 135 Pfam PF05331 Protein of unknown function (DUF742) 23 135 2.0E-40 T 28-03-2018 IPR007995 Protein of unknown function DUF742 SMD44_RS02060 6b0a8ddc925b26d82d5d83f2a8634600 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 300 1.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02060 6b0a8ddc925b26d82d5d83f2a8634600 315 SUPERFAMILY SSF161098 72 297 7.59E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02060 6b0a8ddc925b26d82d5d83f2a8634600 315 Gene3D G3DSA:1.20.58.370 19 60 2.0E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMD44_RS02060 6b0a8ddc925b26d82d5d83f2a8634600 315 Gene3D G3DSA:1.10.3720.10 77 307 4.3E-44 T 28-03-2018 SMD44_RS02745 bbef37d89ba4b11c07e59ac887850ef4 298 SUPERFAMILY SSF161098 24 298 9.25E-71 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS02745 bbef37d89ba4b11c07e59ac887850ef4 298 Gene3D G3DSA:1.10.3720.10 15 286 1.1E-45 T 28-03-2018 SMD44_RS02745 bbef37d89ba4b11c07e59ac887850ef4 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 292 7.0E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD44_RS22705 083db02470a82ea362d37b87e8ad691c 191 Pfam PF12802 MarR family 67 124 2.3E-16 T 28-03-2018 SMD44_RS22705 083db02470a82ea362d37b87e8ad691c 191 SUPERFAMILY SSF46785 40 174 3.62E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22705 083db02470a82ea362d37b87e8ad691c 191 Gene3D G3DSA:1.10.10.10 30 180 8.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS22705 083db02470a82ea362d37b87e8ad691c 191 SMART SM00347 61 159 5.8E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD44_RS04330 e401def93ca56dc2f965d1239cd35165 324 Gene3D G3DSA:3.40.50.2000 127 301 1.2E-20 T 28-03-2018 SMD44_RS04330 e401def93ca56dc2f965d1239cd35165 324 SUPERFAMILY SSF53756 16 314 4.21E-27 T 28-03-2018 SMD44_RS04330 e401def93ca56dc2f965d1239cd35165 324 Pfam PF13692 Glycosyl transferases group 1 152 284 5.1E-11 T 28-03-2018 SMD44_RS31195 390a177175b7ca4710b32e23de60ca6a 318 SUPERFAMILY SSF48239 263 315 4.08E-9 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS31195 390a177175b7ca4710b32e23de60ca6a 318 SUPERFAMILY SSF48239 48 165 4.08E-9 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS31195 390a177175b7ca4710b32e23de60ca6a 318 Gene3D G3DSA:1.50.10.20 46 317 3.1E-19 T 28-03-2018 SMD44_RS38960 ba6447e98534c0341757f66d7f5e4671 406 Gene3D G3DSA:3.60.21.10 170 386 8.0E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS38960 ba6447e98534c0341757f66d7f5e4671 406 SUPERFAMILY SSF56300 168 400 1.69E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS38960 ba6447e98534c0341757f66d7f5e4671 406 Pfam PF00149 Calcineurin-like phosphoesterase 174 341 6.2E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS25300 81cb78cfefa433c97f2da0d903341c4c 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 405 431 1.7E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25300 81cb78cfefa433c97f2da0d903341c4c 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 182 206 1.7E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25300 81cb78cfefa433c97f2da0d903341c4c 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 152 171 1.7E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25300 81cb78cfefa433c97f2da0d903341c4c 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 348 367 1.7E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25300 81cb78cfefa433c97f2da0d903341c4c 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 254 278 1.7E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25300 81cb78cfefa433c97f2da0d903341c4c 526 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 13 522 6.2E-170 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS25300 81cb78cfefa433c97f2da0d903341c4c 526 Pfam PF00361 Proton-conducting membrane transporter 148 432 1.7E-62 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS11905 cf01743238fb8472fef103eb9ca79bae 547 Pfam PF13416 Bacterial extracellular solute-binding protein 111 410 3.0E-14 T 28-03-2018 SMD44_RS11905 cf01743238fb8472fef103eb9ca79bae 547 SUPERFAMILY SSF53850 25 32 5.01E-54 T 28-03-2018 SMD44_RS11905 cf01743238fb8472fef103eb9ca79bae 547 SUPERFAMILY SSF53850 88 545 5.01E-54 T 28-03-2018 SMD44_RS11905 cf01743238fb8472fef103eb9ca79bae 547 Gene3D G3DSA:3.40.190.10 85 234 7.2E-11 T 28-03-2018 SMD44_RS11905 cf01743238fb8472fef103eb9ca79bae 547 Gene3D G3DSA:3.40.190.10 235 418 3.5E-19 T 28-03-2018 SMD44_RS28700 71da40fba30540f7beeeee94dc8605d3 371 Gene3D G3DSA:1.10.620.20 11 301 9.5E-56 T 28-03-2018 SMD44_RS28700 71da40fba30540f7beeeee94dc8605d3 371 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 36 305 6.1E-11 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF SMD44_RS28700 71da40fba30540f7beeeee94dc8605d3 371 SUPERFAMILY SSF47240 89 318 5.41E-67 T 28-03-2018 IPR009078 Ferritin-like superfamily SMD44_RS07860 9abe496a34f60a6a92b798c24fbc9aa2 65 Pfam PF08940 Domain of unknown function (DUF1918) 1 57 3.8E-28 T 28-03-2018 IPR015035 Domain of unknown function DUF1918 SMD44_RS07860 9abe496a34f60a6a92b798c24fbc9aa2 65 SUPERFAMILY SSF50118 1 62 1.44E-23 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMD44_RS29715 9f458bf2824472ed6f5d74f84879f662 225 Pfam PF03458 UPF0126 domain 13 87 5.7E-20 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 SMD44_RS29715 9f458bf2824472ed6f5d74f84879f662 225 Pfam PF03458 UPF0126 domain 99 172 2.8E-19 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 SMD44_RS22565 d54100db2a128ffc65c0e6d1864cce96 375 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 77 218 3.6E-6 T 28-03-2018 SMD44_RS04755 62f5bd73db1b8ec1d16116fd9806bdef 91 SUPERFAMILY SSF46955 19 67 1.74E-7 T 28-03-2018 IPR009061 Putative DNA-binding domain SMD44_RS04755 62f5bd73db1b8ec1d16116fd9806bdef 91 Gene3D G3DSA:1.10.10.10 18 72 2.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS24935 74f9875afc56b5755666cfad00f6ae5c 80 Gene3D G3DSA:1.10.260.40 38 80 3.1E-4 T 28-03-2018 SMD44_RS11465 280c5acec16bc83d45a27d742e655bda 199 Pfam PF11241 Protein of unknown function (DUF3043) 31 196 2.0E-61 T 28-03-2018 IPR021403 Protein of unknown function DUF3043 SMD44_RS02970 9359333a91c7bed9dc443ffa6aaf1b81 113 SUPERFAMILY SSF54593 7 111 1.61E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS02970 9359333a91c7bed9dc443ffa6aaf1b81 113 Gene3D G3DSA:3.10.180.10 6 112 8.7E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS02970 9359333a91c7bed9dc443ffa6aaf1b81 113 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 106 1.5E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS34060 f670293fd3a2984fed1730e4891667ea 118 Pfam PF05331 Protein of unknown function (DUF742) 9 118 1.4E-38 T 28-03-2018 IPR007995 Protein of unknown function DUF742 SMD44_RS21920 cdc9c0d85e6db2efe4044d61c5824661 394 Pfam PF06224 Winged helix DNA-binding domain 37 371 1.1E-56 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 SMD44_RS42655 9e95beb2260057592867575ecfe67972 147 Gene3D G3DSA:1.10.10.10 14 138 0.0011 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS13945 69ed87b54a19324ed97bc060aba7db29 216 Pfam PF01467 Cytidylyltransferase-like 28 188 4.2E-29 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMD44_RS13945 69ed87b54a19324ed97bc060aba7db29 216 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 27 90 1.0E-10 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMD44_RS13945 69ed87b54a19324ed97bc060aba7db29 216 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 28 213 3.2E-53 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SMD44_RS13945 69ed87b54a19324ed97bc060aba7db29 216 Gene3D G3DSA:3.40.50.620 19 215 9.1E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD44_RS13945 69ed87b54a19324ed97bc060aba7db29 216 SUPERFAMILY SSF52374 24 215 2.66E-51 T 28-03-2018 SMD44_RS13945 69ed87b54a19324ed97bc060aba7db29 216 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 24 214 30.207 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SMD44_RS04825 5885ea527041e380bbfcff7cfac888d6 329 Gene3D G3DSA:3.40.630.30 14 172 6.5E-10 T 28-03-2018 SMD44_RS04825 5885ea527041e380bbfcff7cfac888d6 329 SUPERFAMILY SSF55729 59 311 8.56E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS04825 5885ea527041e380bbfcff7cfac888d6 329 Gene3D G3DSA:3.40.630.30 173 324 8.7E-16 T 28-03-2018 SMD44_RS11705 c1ec2a9b2578e488fa19dbabacf3d1f5 149 SUPERFAMILY SSF142906 19 136 2.75E-8 T 28-03-2018 SMD44_RS11705 c1ec2a9b2578e488fa19dbabacf3d1f5 149 Pfam PF04237 YjbR 25 127 1.3E-10 T 28-03-2018 IPR007351 Uncharacterised protein YjbR SMD44_RS02135 04d90c6ab72e976feceb7223b1e1fe73 122 Gene3D G3DSA:3.10.180.10 3 122 3.1E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS02135 04d90c6ab72e976feceb7223b1e1fe73 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 116 7.5E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD44_RS02135 04d90c6ab72e976feceb7223b1e1fe73 122 SUPERFAMILY SSF54593 2 119 7.98E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS21640 a4fe7f224452b0f500cb9131699d9e7f 252 Pfam PF12730 ABC-2 family transporter protein 18 186 4.7E-8 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS35755 e0711f6844f3f904e78586c1e3f6a5c1 280 Pfam PF05709 Phage tail protein 7 276 4.3E-19 T 28-03-2018 IPR008841 Siphovirus-type tail component SMD44_RS24620 29ae11d3736dd1a28bdcce489b6e4735 90 SUPERFAMILY SSF158414 11 69 1.31E-5 T 28-03-2018 IPR029013 HP0062-like domain SMD44_RS24620 29ae11d3736dd1a28bdcce489b6e4735 90 Gene3D G3DSA:1.10.287.850 3 86 9.5E-7 T 28-03-2018 SMD44_RS15945 2051ac81c7f3878ec5ff72adecc8cd83 289 Pfam PF13490 Putative zinc-finger 22 50 4.2E-6 T 28-03-2018 IPR027383 Putative zinc-finger SMD44_RS42585 3d8293852c8327989beb514f37a4899b 635 Pfam PF13556 PucR C-terminal helix-turn-helix domain 469 510 2.1E-8 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMD44_RS00200 d942982f5bf4a5638aff1747e887cebc 790 Gene3D G3DSA:3.40.50.970 187 358 1.5E-5 T 28-03-2018 SMD44_RS00200 d942982f5bf4a5638aff1747e887cebc 790 Gene3D G3DSA:3.40.50.1220 376 544 7.5E-7 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMD44_RS13255 e28c2ec05c95f166b1362f8e6f813096 124 SUPERFAMILY SSF55729 19 102 4.87E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS13255 e28c2ec05c95f166b1362f8e6f813096 124 Gene3D G3DSA:3.40.630.30 6 103 3.5E-7 T 28-03-2018 SMD44_RS42900 ae98c4018511c818faf83d838ecee159 78 Pfam PF04149 Domain of unknown function (DUF397) 16 67 2.6E-14 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS07510 817390e41acac087f5939840f9b99dd8 186 Pfam PF01230 HIT domain 60 151 5.9E-11 T 28-03-2018 IPR001310 Histidine triad (HIT) protein SMD44_RS07510 817390e41acac087f5939840f9b99dd8 186 Gene3D G3DSA:3.30.428.10 8 185 7.9E-44 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS07510 817390e41acac087f5939840f9b99dd8 186 SUPERFAMILY SSF54197 22 176 7.8E-42 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 SMD44_RS27435 ac859c285a4b75bf748247e1099aead1 435 Pfam PF01594 AI-2E family transporter 78 402 5.0E-60 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like SMD44_RS05075 1f7cfe3df8dbe15f2a91fb573ecd13ea 238 Pfam PF06197 Protein of unknown function (DUF998) 44 231 5.1E-33 T 28-03-2018 IPR009339 Protein of unknown function DUF998 SMD44_RS24485 33b1590ecda52b4dc19b2d67f2053057 239 Pfam PF03591 AzlC protein 14 148 3.6E-31 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease SMD44_RS12415 1729b3ecf41999747f902b218464543c 366 Gene3D G3DSA:3.60.15.10 3 324 2.0E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS12415 1729b3ecf41999747f902b218464543c 366 SMART SM00849 30 274 2.7E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS12415 1729b3ecf41999747f902b218464543c 366 SUPERFAMILY SSF56281 14 358 1.83E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS12415 1729b3ecf41999747f902b218464543c 366 Pfam PF00753 Metallo-beta-lactamase superfamily 30 274 3.1E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase SMD44_RS27265 fea41c21c0dddf945c5390b469f159ed 419 SUPERFAMILY SSF52949 216 405 2.86E-11 T 28-03-2018 SMD44_RS27265 fea41c21c0dddf945c5390b469f159ed 419 Gene3D G3DSA:3.40.220.10 194 408 1.1E-12 T 28-03-2018 SMD44_RS35240 25b3faa460d7ee925d83486d4a193b54 181 Pfam PF08044 Domain of unknown function (DUF1707) 11 62 3.8E-16 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 SMD44_RS37455 c6f6eebe8cfc6520a00fa2c9cccc26fe 172 SUPERFAMILY SSF56784 17 156 1.2E-17 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS37455 c6f6eebe8cfc6520a00fa2c9cccc26fe 172 Gene3D G3DSA:3.40.50.1000 17 158 2.5E-17 T 28-03-2018 IPR023214 HAD-like domain SMD44_RS22960 5f04d25cd940d2adfd0fb4ec17d3cbae 241 Gene3D G3DSA:1.10.3210.10 33 166 2.0E-12 T 28-03-2018 SMD44_RS22960 5f04d25cd940d2adfd0fb4ec17d3cbae 241 Pfam PF01966 HD domain 52 140 2.6E-5 T 28-03-2018 IPR006674 HD domain SMD44_RS22960 5f04d25cd940d2adfd0fb4ec17d3cbae 241 SUPERFAMILY SSF109604 50 139 8.48E-13 T 28-03-2018 SMD44_RS33270 acd83d94769c3f55bc616725a8fac22c 374 Pfam PF06224 Winged helix DNA-binding domain 38 355 2.7E-71 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 SMD44_RS27150 605ebe75fda2d530651f52578ac7255b 141 Pfam PF14155 Domain of unknown function (DUF4307) 30 138 2.8E-34 T 28-03-2018 IPR025443 Protein of unknown function DUF4307 SMD44_RS07625 fc145df00de2ff9b52df2a28b12c988f 95 Pfam PF13453 Transcription factor zinc-finger 2 40 1.3E-17 T 28-03-2018 IPR027392 Transcription factor zinc-finger SMD44_RS42565 d3060535c3dbfab9db9d09c374abdc1a 98 Gene3D G3DSA:2.30.30.410 9 98 1.4E-12 T 28-03-2018 SMD44_RS29685 8450ec5ce4d8f59b15ba6cc12cffeb08 244 Pfam PF14581 SseB protein C-terminal domain 120 225 1.5E-18 T 28-03-2018 IPR027945 SseB protein, C-terminal SMD44_RS06625 afb9cc373a391ea9b472b320c614f6d3 300 Pfam PF05949 Bacterial protein of unknown function (DUF881) 162 295 8.0E-39 T 28-03-2018 IPR010273 Protein of unknown function DUF881 SMD44_RS06625 afb9cc373a391ea9b472b320c614f6d3 300 Gene3D G3DSA:1.20.1170.10 44 275 1.7E-4 T 28-03-2018 SMD44_RS09495 67fc51808209ced0d2eb07d8fbf807a4 274 Pfam PF02104 SURF1 family 19 228 2.3E-36 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD44_RS10230 244dc89d1c9de49f5e64d3003c6f64d0 339 Pfam PF03741 Integral membrane protein TerC family 68 274 1.3E-53 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 SMD44_RS10230 244dc89d1c9de49f5e64d3003c6f64d0 339 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 312 1.9E-115 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 SMD44_RS14075 b99e3650285c34c96383f6374b7a155f 122 Pfam PF14017 Protein of unknown function (DUF4233) 2 105 3.2E-33 T 28-03-2018 IPR025327 Protein of unknown function DUF4233 SMD44_RS19440 18f8d608b5861208c6ac5bc20ec7f964 139 Gene3D G3DSA:3.30.565.10 5 135 1.7E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD44_RS21085 0131a6c8a80b0e6a94334e3f67d49585 358 Gene3D G3DSA:3.40.50.300 79 342 9.4E-60 T 28-03-2018 SMD44_RS21085 0131a6c8a80b0e6a94334e3f67d49585 358 Pfam PF13614 AAA domain 80 256 1.3E-56 T 28-03-2018 IPR025669 AAA domain SMD44_RS21085 0131a6c8a80b0e6a94334e3f67d49585 358 SUPERFAMILY SSF52540 80 329 1.09E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS16005 586e77934edac4a7b3411b78ae18c5a7 217 Gene3D G3DSA:3.40.190.10 2 203 4.4E-7 T 28-03-2018 SMD44_RS16905 6f837959f5bab5af1fccfce9119e343c 1041 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 723 822 3.2E-32 T 28-03-2018 IPR032722 Deaminase, Xanthomonas XOO_2897-like SMD44_RS16905 6f837959f5bab5af1fccfce9119e343c 1041 Pfam PF14435 SUKH-4 immunity protein 859 1035 1.3E-40 T 28-03-2018 IPR025851 SUKH-4 immunity protein SMD44_RS09665 c813c15558cf9c37c9afccfec55b64e7 310 SUPERFAMILY SSF53800 5 253 4.8E-54 T 28-03-2018 SMD44_RS09665 c813c15558cf9c37c9afccfec55b64e7 310 Pfam PF01903 CbiX 143 246 4.6E-23 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMD44_RS09665 c813c15558cf9c37c9afccfec55b64e7 310 Pfam PF01903 CbiX 12 116 3.4E-28 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMD44_RS09665 c813c15558cf9c37c9afccfec55b64e7 310 Gene3D G3DSA:3.40.50.1400 2 125 5.8E-31 T 28-03-2018 SMD44_RS09665 c813c15558cf9c37c9afccfec55b64e7 310 Gene3D G3DSA:3.40.50.1400 127 255 3.8E-29 T 28-03-2018 SMD44_RS15980 0ea1f2866203380adfd48d349ceff938 277 SUPERFAMILY SSF47413 29 82 8.89E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS15980 0ea1f2866203380adfd48d349ceff938 277 SMART SM00530 10 83 1.6E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD44_RS15980 0ea1f2866203380adfd48d349ceff938 277 Gene3D G3DSA:1.10.260.40 2 93 4.1E-15 T 28-03-2018 SMD44_RS15980 0ea1f2866203380adfd48d349ceff938 277 Pfam PF13560 Helix-turn-helix domain 6 86 2.7E-15 T 28-03-2018 SMD44_RS24800 bd48eaca79b1aba75763bb740d392688 449 Gene3D G3DSA:1.25.40.10 181 445 1.8E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS24800 bd48eaca79b1aba75763bb740d392688 449 Gene3D G3DSA:1.10.260.40 2 81 3.2E-4 T 28-03-2018 SMD44_RS39345 d42d9fe80ed346357216d951e836a4f5 173 SUPERFAMILY SSF46785 2 169 2.97E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39345 d42d9fe80ed346357216d951e836a4f5 173 Gene3D G3DSA:1.10.10.10 1 88 2.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS39345 d42d9fe80ed346357216d951e836a4f5 173 Pfam PF03551 Transcriptional regulator PadR-like family 6 79 1.1E-16 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS35895 a42384389f89ec8e0b2fe47892754bb7 273 SUPERFAMILY SSF56300 73 94 2.81E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS35895 a42384389f89ec8e0b2fe47892754bb7 273 SUPERFAMILY SSF56300 3 45 2.81E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS35895 a42384389f89ec8e0b2fe47892754bb7 273 SUPERFAMILY SSF56300 124 241 2.81E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS35895 a42384389f89ec8e0b2fe47892754bb7 273 Gene3D G3DSA:3.60.21.10 1 236 1.7E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like SMD44_RS35895 a42384389f89ec8e0b2fe47892754bb7 273 Pfam PF00149 Calcineurin-like phosphoesterase 3 176 4.6E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMD44_RS35895 a42384389f89ec8e0b2fe47892754bb7 273 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 145 159 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD44_RS09605 bb4b75f51055faa029dd273a7817b3c7 313 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 311 92.646 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMD44_RS09605 bb4b75f51055faa029dd273a7817b3c7 313 Pfam PF03186 CobD/Cbib protein 12 289 1.3E-84 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMD44_RS09605 bb4b75f51055faa029dd273a7817b3c7 313 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 15 275 5.1E-53 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMD44_RS16875 daeef7c10675788c5ae7785b142a84e4 861 Pfam PF02687 FtsX-like permease family 763 853 5.9E-13 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS16875 daeef7c10675788c5ae7785b142a84e4 861 Pfam PF02687 FtsX-like permease family 302 397 3.7E-14 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS16875 daeef7c10675788c5ae7785b142a84e4 861 Pfam PF12704 MacB-like periplasmic core domain 502 702 1.7E-9 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS16875 daeef7c10675788c5ae7785b142a84e4 861 Pfam PF12704 MacB-like periplasmic core domain 19 238 4.5E-13 T 28-03-2018 IPR025857 MacB-like periplasmic core domain SMD44_RS26605 58368825f3974072f7b8aa3eed1af734 244 Pfam PF14219 Domain of unknown function (DUF4328) 69 229 7.5E-46 T 28-03-2018 IPR025565 Domain of unknown function DUF4328 SMD44_RS21930 73d9158b0ec5bf89cca311d4878e0c0d 527 Gene3D G3DSA:3.40.50.2300 85 328 4.3E-13 T 28-03-2018 SMD44_RS21930 73d9158b0ec5bf89cca311d4878e0c0d 527 SUPERFAMILY SSF53822 427 497 2.75E-10 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS21930 73d9158b0ec5bf89cca311d4878e0c0d 527 SUPERFAMILY SSF53822 90 381 2.75E-10 T 28-03-2018 IPR028082 Periplasmic binding protein-like I SMD44_RS38195 52da7e24972fcc503fef2f368a6ed94b 253 Pfam PF08241 Methyltransferase domain 37 125 2.9E-14 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS38195 52da7e24972fcc503fef2f368a6ed94b 253 SUPERFAMILY SSF53335 3 152 1.58E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38195 52da7e24972fcc503fef2f368a6ed94b 253 SUPERFAMILY SSF53335 184 205 1.58E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38195 52da7e24972fcc503fef2f368a6ed94b 253 Gene3D G3DSA:3.40.50.150 1 224 4.1E-30 T 28-03-2018 SMD44_RS30620 9aa2530ffb7f260bc1922d797697df29 134 Gene3D G3DSA:3.10.180.10 1 134 3.7E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS30620 9aa2530ffb7f260bc1922d797697df29 134 SUPERFAMILY SSF54593 4 129 1.16E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS32395 691563429df30e12d045315bbdd83d8d 398 Pfam PF14257 Domain of unknown function (DUF4349) 57 339 9.9E-72 T 28-03-2018 IPR025645 Domain of unknown function DUF4349 SMD44_RS18310 aed7a492758d18e68a34b5f7c63da563 168 Gene3D G3DSA:3.40.50.1390 61 154 1.5E-4 T 28-03-2018 SMD44_RS15905 63c7eeb825d47f614d5c760703e6d65d 98 Pfam PF11238 Protein of unknown function (DUF3039) 28 83 3.6E-32 T 28-03-2018 IPR021400 Protein of unknown function DUF3039 SMD44_RS30305 475dd787b3f999d206d64ddbacf91ae0 281 Gene3D G3DSA:3.40.1190.20 15 276 7.1E-60 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS30305 475dd787b3f999d206d64ddbacf91ae0 281 Pfam PF08543 Phosphomethylpyrimidine kinase 27 269 6.2E-91 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 SMD44_RS30305 475dd787b3f999d206d64ddbacf91ae0 281 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 20 270 4.8E-94 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD44_RS30305 475dd787b3f999d206d64ddbacf91ae0 281 SUPERFAMILY SSF53613 17 272 7.48E-77 T 28-03-2018 IPR029056 Ribokinase-like SMD44_RS11315 9ef51ca210fdc9b7eb8cc08366db0daf 449 Gene3D G3DSA:1.20.1170.10 45 278 1.0E-6 T 28-03-2018 SMD44_RS11315 9ef51ca210fdc9b7eb8cc08366db0daf 449 Pfam PF05991 YacP-like NYN domain 328 446 1.0E-16 T 28-03-2018 IPR010298 Protein of unknown function DUF901 SMD44_RS13075 c1bcc78bb3acaf97ddc5c96b492a9595 304 Gene3D G3DSA:1.25.40.10 9 295 2.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS16405 d92c2f6ea22eba1bf54a3114dbf1e820 538 Pfam PF02652 L-lactate permease 15 525 9.0E-136 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SMD44_RS16405 d92c2f6ea22eba1bf54a3114dbf1e820 538 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 14 526 6.6E-134 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SMD44_RS09380 d45678c24c10a428db0875612e4f41e9 466 Pfam PF01523 Putative modulator of DNA gyrase 26 327 1.2E-36 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMD44_RS09380 d45678c24c10a428db0875612e4f41e9 466 SUPERFAMILY SSF111283 11 459 1.44E-64 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMD44_RS09380 d45678c24c10a428db0875612e4f41e9 466 Gene3D G3DSA:3.30.2290.10 2 216 3.1E-44 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SMD44_RS05205 b37aa8976451fdcf7a44649dc0bf898c 199 Pfam PF06271 RDD family 1 170 7.9E-9 T 28-03-2018 IPR010432 RDD SMD44_RS25290 a7fb02f273ad585cb0a230b2b108a5ae 136 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 1.3E-26 T 28-03-2018 SMD44_RS25290 a7fb02f273ad585cb0a230b2b108a5ae 136 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 102 18.697 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SMD44_RS10040 46cb9a634c559c834aaee6a3a968c662 357 Pfam PF02628 Cytochrome oxidase assembly protein 55 274 4.5E-18 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 SMD44_RS01445 75462faf8527093a20283c86d46dd3f8 399 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 18 385 7.7E-84 T 28-03-2018 IPR010640 Low temperature requirement A SMD44_RS16315 00a4c46802d464ab4b5ad5ead9cb4f46 197 Pfam PF13559 Domain of unknown function (DUF4129) 101 171 2.4E-16 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 SMD44_RS17010 6c99b564cd097973020f35aa0509bedf 565 Pfam PF00474 Sodium:solute symporter family 52 461 4.1E-48 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS17010 6c99b564cd097973020f35aa0509bedf 565 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 52 461 2.7E-66 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS26670 e75571d6333eb1ba05d492dd9100b793 326 Pfam PF00535 Glycosyl transferase family 2 5 115 4.9E-34 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS26670 e75571d6333eb1ba05d492dd9100b793 326 Gene3D G3DSA:3.90.550.10 1 291 3.7E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS26670 e75571d6333eb1ba05d492dd9100b793 326 SUPERFAMILY SSF53448 3 231 4.82E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS22360 f6cfab57fd3747c4cb66ad5074d18d74 86 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 37 1.5E-5 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 SMD44_RS22360 f6cfab57fd3747c4cb66ad5074d18d74 86 Gene3D G3DSA:1.10.1220.10 1 79 1.6E-7 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD44_RS41070 483dec2cf6128e362b588cd45c6fc1ea 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 29 97 4.2E-21 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 SMD44_RS41070 483dec2cf6128e362b588cd45c6fc1ea 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 113 184 4.8E-16 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 SMD44_RS41070 483dec2cf6128e362b588cd45c6fc1ea 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 210 278 4.3E-16 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 SMD44_RS23085 df8a03ba4e51732d33603e0505a968f2 142 Gene3D G3DSA:3.40.630.30 2 125 3.1E-5 T 28-03-2018 SMD44_RS16890 96edb99600ee9f7d8a74d439a15f4102 149 Pfam PF04341 Protein of unknown function, DUF485 51 137 5.6E-18 T 28-03-2018 IPR007436 Protein of unknown function DUF485 SMD44_RS02955 e52b5dea3fc9874e0820403ee97185ff 237 Pfam PF14021 Tuberculosis necrotizing toxin 126 228 1.7E-33 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin SMD44_RS10715 51099850c418248d1812e9be430a5d4f 243 Pfam PF01988 VIT family 28 235 3.7E-63 T 28-03-2018 IPR008217 Ccc1 family SMD44_RS09640 50d702d4b86f50fdb66aa47f32f160bf 243 Pfam PF02535 ZIP Zinc transporter 88 237 1.1E-13 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD44_RS14435 8999a0d93271c7959a8b46672a358e4c 742 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 160 709 6.3E-91 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD44_RS14435 8999a0d93271c7959a8b46672a358e4c 742 SUPERFAMILY SSF51445 196 626 3.54E-137 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS14435 8999a0d93271c7959a8b46672a358e4c 742 SUPERFAMILY SSF51445 655 732 3.54E-137 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS14435 8999a0d93271c7959a8b46672a358e4c 742 Gene3D G3DSA:3.20.20.80 193 729 2.5E-180 T 28-03-2018 SMD44_RS14435 8999a0d93271c7959a8b46672a358e4c 742 Pfam PF02446 4-alpha-glucanotransferase 202 709 7.5E-114 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD44_RS27875 d50ef743348f45816a8c6ae8e204f224 162 Pfam PF02416 mttA/Hcf106 family 5 44 2.5E-5 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMD44_RS27875 d50ef743348f45816a8c6ae8e204f224 162 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 156 14.083 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 SMD44_RS27875 d50ef743348f45816a8c6ae8e204f224 162 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.0E-8 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMD44_RS27875 d50ef743348f45816a8c6ae8e204f224 162 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.0E-8 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMD44_RS27875 d50ef743348f45816a8c6ae8e204f224 162 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.0E-8 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMD44_RS28400 10de6a3fa981683fb416f28e1035a943 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 19.15 T 28-03-2018 IPR003482 Transcription factor WhiB SMD44_RS28400 10de6a3fa981683fb416f28e1035a943 85 Pfam PF02467 Transcription factor WhiB 3 71 1.6E-27 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS20535 aa3251a7627b7bb60d74acede497d26f 276 Pfam PF10935 Protein of unknown function (DUF2637) 1 72 2.9E-6 T 28-03-2018 IPR021235 Protein of unknown function DUF2637 SMD44_RS35290 f21626016d1cc7de3cc03b39dd177167 277 SUPERFAMILY SSF51621 7 276 7.18E-61 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD44_RS35290 f21626016d1cc7de3cc03b39dd177167 277 Gene3D G3DSA:3.20.20.60 1 267 1.1E-58 T 28-03-2018 SMD44_RS35290 f21626016d1cc7de3cc03b39dd177167 277 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 254 4.5E-76 T 28-03-2018 SMD44_RS25310 d509d58406fb678197e446d80b6de95c 287 Hamap MF_00188 Protease HtpX [htpX]. 7 282 27.749 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 SMD44_RS25310 d509d58406fb678197e446d80b6de95c 287 Pfam PF01435 Peptidase family M48 68 282 2.5E-35 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD44_RS25310 d509d58406fb678197e446d80b6de95c 287 Gene3D G3DSA:3.30.2010.10 58 150 9.3E-20 T 28-03-2018 SMD44_RS20130 5df444e5d359b713b43e972f58078c71 71 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 49 1.2E-10 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB SMD44_RS18450 212188f84d191fc9855a64e817d44e43 90 Pfam PF04149 Domain of unknown function (DUF397) 26 82 2.7E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS18450 212188f84d191fc9855a64e817d44e43 90 Pfam PF04149 Domain of unknown function (DUF397) 6 24 1.0E-6 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS13665 87cb8cc619e383ab59f7faeeb4b19dab 358 Gene3D G3DSA:2.120.10.10 1 358 2.2E-68 T 28-03-2018 SMD44_RS13665 87cb8cc619e383ab59f7faeeb4b19dab 358 SUPERFAMILY SSF50939 3 356 2.8E-81 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD44_RS13665 87cb8cc619e383ab59f7faeeb4b19dab 358 Pfam PF13088 BNR repeat-like domain 24 336 1.8E-43 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD44_RS34865 cf06e98109ae9b41062a930afa4e6ccd 303 SUPERFAMILY SSF56563 110 249 4.18E-5 T 28-03-2018 SMD44_RS08775 2652fc5479bf6c04d587a0f5569464e2 502 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 437 2.4E-139 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane SMD44_RS17340 66a1d8ada9dead752a4f1eb6a2a1d307 184 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 76 184 3.5E-7 T 28-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain SMD44_RS04580 786fbec61c233c7bcc871e94b27d4422 179 Pfam PF07799 Protein of unknown function (DUF1643) 31 163 5.6E-37 T 28-03-2018 IPR012441 Protein of unknown function DUF1643 SMD44_RS04580 786fbec61c233c7bcc871e94b27d4422 179 Gene3D G3DSA:3.20.20.70 19 154 2.8E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS12550 c042034a9fb2b82cad52d62dc94b740f 206 Pfam PF09335 SNARE associated Golgi protein 35 166 1.9E-9 T 28-03-2018 IPR032816 SNARE associated Golgi protein SMD44_RS09390 d3afdcf120f2c85cb7785ccb61fd65bc 91 Pfam PF04226 Transglycosylase associated protein 33 79 3.0E-7 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SMD44_RS28745 1f222f8bdc5e70c37c48596bd8863a8b 267 Pfam PF08378 Nuclease-related domain 118 161 1.1E-4 T 28-03-2018 IPR011528 Nuclease-related domain, NERD SMD44_RS26435 38ed94cae727beea1a9df5d2a55867bb 399 Gene3D G3DSA:3.40.190.10 2 262 5.0E-5 T 28-03-2018 SMD44_RS05910 76cd13c8f194079663047ee5018f5e78 470 Pfam PF03055 Retinal pigment epithelial membrane protein 12 443 4.8E-98 T 28-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 SMD44_RS35370 13bb9d6d8987a86f2b99638062dd3223 278 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 14 254 7.7E-52 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 SMD44_RS28560 4c3ca74e030685de05097bbcd04a9c53 332 Pfam PF13349 Putative adhesin 123 262 1.5E-8 T 28-03-2018 IPR025164 Putative adhesin SMD44_RS26065 a8ca579f85969f7645b7f231a202c230 203 Pfam PF11222 Protein of unknown function (DUF3017) 111 180 1.5E-20 T 28-03-2018 IPR021385 Protein of unknown function DUF3017 SMD44_RS16050 58f53343f9c9abb8015ca187039341cf 305 PIRSF PIRSF003097 1 305 9.6E-75 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 SMD44_RS38810 c7efd22408df50182b9e3440a8e721d9 264 Gene3D G3DSA:3.90.550.10 1 252 7.1E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS38810 c7efd22408df50182b9e3440a8e721d9 264 SUPERFAMILY SSF53448 1 255 1.17E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS27890 34fcc09e70529689f4046673fe626d9c 194 Pfam PF06210 Protein of unknown function (DUF1003) 60 161 1.5E-40 T 28-03-2018 IPR010406 Protein of unknown function DUF1003 SMD44_RS08150 751484582dca70c059ed134208c63448 85 Pfam PF02945 Recombination endonuclease VII 15 67 2.3E-14 T 28-03-2018 IPR004211 Recombination endonuclease VII SMD44_RS08150 751484582dca70c059ed134208c63448 85 SUPERFAMILY SSF54060 20 72 2.71E-9 T 28-03-2018 SMD44_RS43145 1a9025602d649956e83c853e72e72190 324 Gene3D G3DSA:2.60.40.10 218 316 2.0E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS43145 1a9025602d649956e83c853e72e72190 324 Gene3D G3DSA:2.60.40.10 79 180 0.36 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS02610 4aa471089a989acb556b51db4decae3c 200 Pfam PF11066 Protein of unknown function (DUF2867) 19 178 1.6E-33 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 SMD44_RS23285 291bc50e8a407c9f1e0d714485196462 144 Pfam PF07811 TadE-like protein 32 74 1.6E-6 T 28-03-2018 IPR012495 TadE-like SMD44_RS29160 fb76206ae582f4364877ff5b874528db 65 Pfam PF04149 Domain of unknown function (DUF397) 8 62 9.2E-19 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS01245 e7b9bf7907fa86070e863412b38f067e 134 Gene3D G3DSA:3.30.1330.40 3 129 1.3E-33 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS01245 e7b9bf7907fa86070e863412b38f067e 134 Pfam PF01042 Endoribonuclease L-PSP 15 128 1.3E-23 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS01245 e7b9bf7907fa86070e863412b38f067e 134 SUPERFAMILY SSF55298 4 130 6.75E-33 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS17210 3fdb2bdc4dcd62f25aa213851205d7e9 64 Gene3D G3DSA:1.10.287.700 2 64 1.9E-6 T 28-03-2018 SMD44_RS25825 5ffe256338e73aecb168ee65d68f27c2 196 SUPERFAMILY SSF81995 3 65 3.4E-7 T 28-03-2018 SMD44_RS32470 728e7f0124a0f33ec107546d8706a63b 136 SUPERFAMILY SSF54593 5 117 1.78E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS32470 728e7f0124a0f33ec107546d8706a63b 136 Gene3D G3DSA:3.10.180.10 2 124 1.4E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS10890 fb8999ba7d04bf0893d0b8af6c05eb82 273 Pfam PF01061 ABC-2 type transporter 48 233 2.8E-14 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS02095 d5c252cfdca2015a150124fe0363972f 412 SUPERFAMILY SSF51445 80 292 5.8E-14 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily SMD44_RS02095 d5c252cfdca2015a150124fe0363972f 412 Gene3D G3DSA:3.20.20.80 62 403 7.1E-20 T 28-03-2018 SMD44_RS16855 cddecb4b49ad518e54b992775582a745 58 Pfam PF14013 MT0933-like antitoxin protein 9 49 7.6E-9 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 SMD44_RS05610 96dddb0818dab584414a36d366a33c65 319 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 41 284 1.8E-83 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related SMD44_RS10420 555efdedb999c91bfb124f15c7e1436b 150 SUPERFAMILY SSF55298 17 145 2.67E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS10420 555efdedb999c91bfb124f15c7e1436b 150 Pfam PF01042 Endoribonuclease L-PSP 29 144 7.0E-18 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family SMD44_RS10420 555efdedb999c91bfb124f15c7e1436b 150 Gene3D G3DSA:3.30.1330.40 10 150 1.4E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD44_RS03190 afb11593c9f78cd7e4b4394c039814bd 499 SUPERFAMILY SSF48452 242 438 2.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS03190 afb11593c9f78cd7e4b4394c039814bd 499 Gene3D G3DSA:1.25.40.10 187 491 1.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS25440 92d9e657fbaf629469d8c93dc9fde628 285 SUPERFAMILY SSF89392 40 266 1.61E-26 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD44_RS29120 a28dee46d05d8e49e36ec82fe797cac2 326 Gene3D G3DSA:1.10.10.10 175 325 4.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29120 a28dee46d05d8e49e36ec82fe797cac2 326 Pfam PF12840 Helix-turn-helix domain 260 306 3.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS29120 a28dee46d05d8e49e36ec82fe797cac2 326 SUPERFAMILY SSF46785 251 322 6.07E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS17020 49c288d993f0c1a973daccb2acc85aa3 323 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 244 7.5E-60 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMD44_RS17020 49c288d993f0c1a973daccb2acc85aa3 323 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 321 4.0E-118 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 SMD44_RS17020 49c288d993f0c1a973daccb2acc85aa3 323 SUPERFAMILY SSF51735 1 320 1.17E-92 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS17020 49c288d993f0c1a973daccb2acc85aa3 323 Gene3D G3DSA:3.90.25.10 173 323 2.8E-38 T 28-03-2018 SMD44_RS17020 49c288d993f0c1a973daccb2acc85aa3 323 Gene3D G3DSA:3.40.50.720 4 172 1.4E-33 T 28-03-2018 SMD44_RS00010 ae18389a13cec9df86be064037bcd251 298 Gene3D G3DSA:3.40.1350.10 59 199 1.5E-13 T 28-03-2018 SMD44_RS09300 549ccae15fb2ad9b100706e0ceef8109 81 Pfam PF03777 Small secreted domain (DUF320) 25 80 3.3E-25 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS07490 d74cb0644d1a8bd6551d7e843d85e414 319 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 8 293 2.0E-61 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 SMD44_RS10080 f9e76d6060fc942807e752265c224262 354 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 300 1.4E-96 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA SMD44_RS10080 f9e76d6060fc942807e752265c224262 354 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 299 3.8E-82 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA SMD44_RS16360 cdb14741e32ba2fed8bd52e370a30e18 335 Pfam PF06271 RDD family 13 140 1.4E-18 T 28-03-2018 IPR010432 RDD SMD44_RS33805 fc392947bc9c82d250e16eb73facd10f 64 Pfam PF03771 Domain of unknown function (DUF317) 8 37 2.3E-6 T 28-03-2018 IPR005523 Domain of unknown function DUF317 SMD44_RS22560 44c05919aae3128c204b12909b72f32e 180 Pfam PF10722 Putative bacterial sensory transduction regulator 31 156 2.2E-17 T 28-03-2018 IPR019660 Putative sensory transduction regulator YbjN SMD44_RS13130 9ceff536847d2020975d5c3b5cee64b3 413 Gene3D G3DSA:3.30.70.270 122 249 1.9E-4 T 28-03-2018 SMD44_RS18455 17e899b5504be81d896413e90c50f91a 434 Pfam PF04235 Protein of unknown function (DUF418) 254 432 3.6E-34 T 28-03-2018 IPR007349 Domain of unknown function DUF418 SMD44_RS06575 30979c7c7c962bf8fa604fadf8d80d22 506 PIRSF PIRSF012666 1 498 2.4E-222 T 28-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 SMD44_RS06575 30979c7c7c962bf8fa604fadf8d80d22 506 SUPERFAMILY SSF55931 39 464 1.67E-44 T 28-03-2018 SMD44_RS14615 c6af99f98b85f8177cabcc68eb82d993 512 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 119 166 2.4E-15 T 28-03-2018 IPR023849 Uncharacterised domain CHP03934, TQXA SMD44_RS14615 c6af99f98b85f8177cabcc68eb82d993 512 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 450 484 5.9E-4 T 28-03-2018 SMD44_RS14615 c6af99f98b85f8177cabcc68eb82d993 512 Pfam PF05506 Domain of unknown function (DUF756) 352 413 4.0E-8 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMD44_RS34350 ed1adaad793add6cc9ce8b6f5bd0da61 255 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 238 8.5E-65 T 28-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMD44_RS06145 24d988b231f48a9a6f46ad8dc85e4896 151 Pfam PF05099 Tellurite resistance protein TerB 10 150 1.3E-31 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal SMD44_RS06145 24d988b231f48a9a6f46ad8dc85e4896 151 SUPERFAMILY SSF158682 16 150 9.81E-23 T 28-03-2018 SMD44_RS06145 24d988b231f48a9a6f46ad8dc85e4896 151 Gene3D G3DSA:1.10.3680.10 3 151 8.0E-23 T 28-03-2018 IPR029024 TerB-like SMD44_RS29980 29d73de0fe179aecb03c55b4cf2628fd 287 Pfam PF01148 Cytidylyltransferase family 45 285 5.9E-35 T 28-03-2018 SMD44_RS03830 17926522217833f27e8ab6b072c1e006 167 Gene3D G3DSA:2.60.40.1120 21 128 9.5E-5 T 28-03-2018 SMD44_RS14355 d1cee29d831d83d4dfbbc1972461e3b2 62 Pfam PF04149 Domain of unknown function (DUF397) 6 58 6.7E-14 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS18030 8ccf4ec31ddb64c259385308db3918fb 176 Pfam PF08877 MepB protein 37 157 7.5E-47 T 28-03-2018 IPR011235 MepB-like SMD44_RS33335 854caffe13633f7710736630039cecf4 272 PIRSF PIRSF006241 4 272 3.6E-82 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 SMD44_RS33335 854caffe13633f7710736630039cecf4 272 Pfam PF01261 Xylose isomerase-like TIM barrel 26 229 1.3E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS33335 854caffe13633f7710736630039cecf4 272 Gene3D G3DSA:3.20.20.150 5 272 7.5E-50 T 28-03-2018 SMD44_RS33335 854caffe13633f7710736630039cecf4 272 SUPERFAMILY SSF51658 9 270 2.49E-58 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMD44_RS21335 947e231cb3770978b88b0193eddcc293 82 Pfam PF03777 Small secreted domain (DUF320) 28 81 8.5E-22 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS32315 0ac2c831467200121e73252402938278 507 PIRSF PIRSF006060 6 499 3.0E-92 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS32315 0ac2c831467200121e73252402938278 507 Pfam PF13520 Amino acid permease 29 458 1.9E-54 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS04385 9c9e44d2ed4128bf0792fc6f579e5e63 125 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 19 77 4.4E-6 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component SMD44_RS08780 0e5684e51050534d3bab103b0c1709d5 181 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 30 173 6.9E-22 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 SMD44_RS09295 38cc86d18ae10214bdd007242fea659a 81 Pfam PF03777 Small secreted domain (DUF320) 25 80 1.9E-24 T 28-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD44_RS05400 b241c1add6bbb83876724a16d13712cc 301 Pfam PF03458 UPF0126 domain 17 89 4.4E-16 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 SMD44_RS05400 b241c1add6bbb83876724a16d13712cc 301 Pfam PF03458 UPF0126 domain 102 175 1.8E-15 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 SMD44_RS12035 307f43a5ac317111b511f9d5c52b73e1 216 Pfam PF02567 Phenazine biosynthesis-like protein 14 88 6.2E-8 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD44_RS12035 307f43a5ac317111b511f9d5c52b73e1 216 SUPERFAMILY SSF54506 4 209 1.67E-23 T 28-03-2018 SMD44_RS12035 307f43a5ac317111b511f9d5c52b73e1 216 Gene3D G3DSA:3.10.310.10 20 206 3.6E-23 T 28-03-2018 SMD44_RS18280 1dea287e8f47dc58003bef3d5ba67061 583 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 24 358 1.7E-123 T 28-03-2018 IPR010839 Acyclic terpene utilisation SMD44_RS02880 e05f16a08fe5049dfa84f827677c837a 170 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 13 136 1.8E-13 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase SMD44_RS02880 e05f16a08fe5049dfa84f827677c837a 170 SUPERFAMILY SSF55961 12 168 8.76E-23 T 28-03-2018 SMD44_RS02880 e05f16a08fe5049dfa84f827677c837a 170 Gene3D G3DSA:3.30.530.20 6 170 2.9E-30 T 28-03-2018 IPR023393 START-like domain SMD44_RS19230 9e51cd9c940b31e0f43c31ae0c07c638 327 Pfam PF06089 L-asparaginase II 21 324 2.2E-113 T 28-03-2018 IPR010349 L-asparaginase II SMD44_RS15355 d986896daf7f3167eba8e6bab71fc550 245 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 1 220 5.7E-50 T 28-03-2018 IPR012666 Cobalt transporter subunit CbtA, putative SMD44_RS15830 ff47e2c01aacc295233a23bbd453f2a0 146 Pfam PF06236 Tyrosinase co-factor MelC1 11 128 2.3E-44 T 28-03-2018 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 SMD44_RS27350 27703d580555a153b79987c2df7c9015 110 Pfam PF07811 TadE-like protein 2 40 3.9E-7 T 28-03-2018 IPR012495 TadE-like SMD44_RS31415 dab04453e3a866718c1c48e43c4059ed 655 Pfam PF06276 Ferric iron reductase FhuF-like transporter 473 633 2.3E-37 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain SMD44_RS31415 dab04453e3a866718c1c48e43c4059ed 655 Pfam PF04183 IucA / IucC family 201 451 1.2E-72 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMD44_RS30660 e101b79f5d14e04afe76d4a694dcbf4c 139 Gene3D G3DSA:3.40.190.10 1 114 6.6E-5 T 28-03-2018 SMD44_RS24175 2702446e497d5f6eaf9368b1aac8ab7e 178 Pfam PF14016 Protein of unknown function (DUF4232) 43 169 5.8E-20 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 SMD44_RS26660 0d76fc5f8f4da2b09d48e4445b8fa0ad 308 Pfam PF13578 Methyltransferase domain 46 167 2.3E-13 T 28-03-2018 SMD44_RS26660 0d76fc5f8f4da2b09d48e4445b8fa0ad 308 Gene3D G3DSA:3.40.50.150 16 187 1.9E-6 T 28-03-2018 SMD44_RS26660 0d76fc5f8f4da2b09d48e4445b8fa0ad 308 SUPERFAMILY SSF53335 27 173 1.66E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS04535 2c3c8b6031e4c52df2dd146ace1840ad 153 Pfam PF03374 Phage antirepressor protein KilAC domain 35 140 3.5E-16 T 28-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 SMD44_RS27365 b07f99735b4f2b3b646581199580d6e7 296 Pfam PF00482 Type II secretion system (T2SS), protein F 153 278 1.7E-21 T 28-03-2018 IPR018076 Type II secretion system F domain SMD44_RS33140 264166740876e6c65870b8378d6ea9b0 222 Pfam PF13699 Domain of unknown function (DUF4157) 95 165 5.4E-14 T 28-03-2018 IPR025295 Domain of unknown function DUF4157 SMD44_RS15780 81514914c3385c33c4621079eb94a309 207 Gene3D G3DSA:1.10.10.10 5 176 1.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15780 81514914c3385c33c4621079eb94a309 207 SUPERFAMILY SSF46785 29 106 1.96E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15780 81514914c3385c33c4621079eb94a309 207 Pfam PF12840 Helix-turn-helix domain 32 84 1.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS15780 81514914c3385c33c4621079eb94a309 207 SMART SM00418 27 123 4.1E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD44_RS21375 8598c1b3433ca8eaa9e7430a0edfafda 228 Pfam PF01339 CheB methylesterase 43 218 2.2E-56 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SMD44_RS21375 8598c1b3433ca8eaa9e7430a0edfafda 228 Gene3D G3DSA:3.40.50.180 31 228 1.2E-68 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SMD44_RS21375 8598c1b3433ca8eaa9e7430a0edfafda 228 SUPERFAMILY SSF52738 40 224 1.96E-60 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 SMD44_RS32445 5e9db51323ce7f115b8b3bdb4d89b51d 222 Gene3D G3DSA:2.60.40.1240 56 220 5.9E-10 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain SMD44_RS37000 9b91c469c7adbf9a250b519b107b998f 72 PRINTS PR01217 Proline rich extensin signature 27 48 1.2E-9 T 28-03-2018 SMD44_RS37000 9b91c469c7adbf9a250b519b107b998f 72 PRINTS PR01217 Proline rich extensin signature 8 20 1.2E-9 T 28-03-2018 SMD44_RS37000 9b91c469c7adbf9a250b519b107b998f 72 PRINTS PR01217 Proline rich extensin signature 49 65 1.2E-9 T 28-03-2018 SMD44_RS02440 17c0ff38bf1598b525b789838f395d4f 350 SUPERFAMILY SSF103481 64 155 1.7E-11 T 28-03-2018 SMD44_RS02440 17c0ff38bf1598b525b789838f395d4f 350 Pfam PF00892 EamA-like transporter family 27 151 2.6E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS02440 17c0ff38bf1598b525b789838f395d4f 350 Pfam PF00892 EamA-like transporter family 162 294 3.7E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMD44_RS02440 17c0ff38bf1598b525b789838f395d4f 350 SUPERFAMILY SSF103481 197 302 4.45E-14 T 28-03-2018 SMD44_RS21650 2fad9c13a07bd066ffc634ac7cda4061 470 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 51 450 2.2E-136 T 28-03-2018 IPR018721 Protein of unknown function DUF2252 SMD44_RS29075 1f74a9c17510ac0cbe0ae8c307824cfe 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 12 93 8.2E-23 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SMD44_RS29075 1f74a9c17510ac0cbe0ae8c307824cfe 114 Pfam PF12823 Domain of unknown function (DUF3817) 9 95 7.2E-23 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SMD44_RS22775 20b474533b2b6b5dbf48aca8ccc17891 219 Pfam PF16702 Domain of unknown function (DUF5063) 12 173 1.1E-45 T 28-03-2018 IPR032025 Protein of unknown function DUF5063 SMD44_RS21265 7455544e743b453fc5c4cae5e827bc65 471 SUPERFAMILY SSF56059 125 327 3.72E-20 T 28-03-2018 SMD44_RS21265 7455544e743b453fc5c4cae5e827bc65 471 Gene3D G3DSA:3.30.470.20 132 427 9.5E-29 T 28-03-2018 SMD44_RS21265 7455544e743b453fc5c4cae5e827bc65 471 Gene3D G3DSA:3.40.640.10 15 131 0.0016 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS27005 1f98c58f0648d4e0ff53507e582c7a2c 284 Pfam PF01391 Collagen triple helix repeat (20 copies) 94 146 1.3E-8 T 28-03-2018 IPR008160 Collagen triple helix repeat SMD44_RS00715 7afb0ae203deaadc975d38337760c6fe 190 Gene3D G3DSA:1.10.260.40 24 168 8.5E-4 T 28-03-2018 SMD44_RS43625 8c79c5c294c08c5cde14a4c6baa29226 130 Gene3D G3DSA:1.10.10.10 51 102 0.0019 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS08415 1c66f6720bb18e0492e0453a8c2c4376 449 Pfam PF13148 Protein of unknown function (DUF3987) 102 311 1.9E-21 T 28-03-2018 IPR025048 Protein of unknown function DUF3987) SMD44_RS27380 e889dde9b9d0cb972b4cddec5a3c9a5f 193 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 8 45 1.6E-5 T 28-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SMD44_RS32705 7b329753a934c3a28727e1743ecf280f 442 Pfam PF01179 Copper amine oxidase, enzyme domain 67 425 1.6E-37 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMD44_RS32705 7b329753a934c3a28727e1743ecf280f 442 SUPERFAMILY SSF49998 44 427 4.84E-69 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMD44_RS32705 7b329753a934c3a28727e1743ecf280f 442 Gene3D G3DSA:2.70.98.20 41 430 3.4E-69 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMD44_RS42520 6f2f1c3c80ff9ce88b52417c6240348c 195 Gene3D G3DSA:3.40.190.10 1 182 2.8E-5 T 28-03-2018 SMD44_RS12360 3729c9190314d82b50999ee9d1e0de03 254 Gene3D G3DSA:3.40.50.150 3 180 1.5E-37 T 28-03-2018 SMD44_RS12360 3729c9190314d82b50999ee9d1e0de03 254 Pfam PF08241 Methyltransferase domain 18 121 4.0E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD44_RS12360 3729c9190314d82b50999ee9d1e0de03 254 SUPERFAMILY SSF53335 9 236 1.26E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS43720 3b665c9542832d96d83ca104fc67a08e 463 SUPERFAMILY SSF48452 297 419 3.8E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS43720 3b665c9542832d96d83ca104fc67a08e 463 Gene3D G3DSA:1.25.40.10 346 462 1.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS43720 3b665c9542832d96d83ca104fc67a08e 463 Gene3D G3DSA:1.25.40.10 16 339 2.5E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD44_RS41120 fb04baedf88eb5794c49230081b999ac 357 Gene3D G3DSA:2.130.10.10 48 347 1.7E-6 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD44_RS30870 1c6348d2f68e715b63b905985b62213d 98 Pfam PF04456 Protein of unknown function (DUF503) 3 89 1.9E-32 T 28-03-2018 IPR007546 Protein of unknown function DUF503 SMD44_RS30870 1c6348d2f68e715b63b905985b62213d 98 Gene3D G3DSA:3.30.70.1120 2 92 3.1E-34 T 28-03-2018 SMD44_RS30870 1c6348d2f68e715b63b905985b62213d 98 SUPERFAMILY SSF103007 1 94 4.84E-31 T 28-03-2018 IPR007546 Protein of unknown function DUF503 SMD44_RS22940 255913afbff9e11249cc09bb19c1788f 282 Gene3D G3DSA:3.90.550.10 21 275 3.3E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS22940 255913afbff9e11249cc09bb19c1788f 282 SUPERFAMILY SSF53448 38 251 2.06E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS22940 255913afbff9e11249cc09bb19c1788f 282 Pfam PF00535 Glycosyl transferase family 2 41 146 2.3E-10 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD44_RS04975 ff281bd5a387177526bd010db680773d 205 Gene3D G3DSA:3.10.490.10 2 199 1.2E-20 T 28-03-2018 SMD44_RS14210 46cc664c8c5a9f5862a1e411598f7ebe 120 Pfam PF14373 Superinfection immunity protein 64 104 5.4E-12 T 28-03-2018 IPR016410 Bacteriophage-associated immunity protein SMD44_RS12520 d2fece112f656d755bdc9132b9427974 192 Pfam PF01169 Uncharacterized protein family UPF0016 110 183 7.5E-18 T 28-03-2018 IPR001727 Gdt1 family SMD44_RS12520 d2fece112f656d755bdc9132b9427974 192 Pfam PF01169 Uncharacterized protein family UPF0016 10 79 3.0E-15 T 28-03-2018 IPR001727 Gdt1 family SMD44_RS24700 0c07fd5f7cee5bd7fffcd3f9a3c7ef3c 146 Pfam PF07811 TadE-like protein 21 63 6.6E-9 T 28-03-2018 IPR012495 TadE-like SMD44_RS10415 0d2f663fa9d656a1127f4e87c7480fd0 335 SUPERFAMILY SSF82171 129 326 9.22E-11 T 28-03-2018 SMD44_RS10415 0d2f663fa9d656a1127f4e87c7480fd0 335 Gene3D G3DSA:2.130.10.120 126 334 2.5E-15 T 28-03-2018 SMD44_RS00040 cb9f67a520fd099d72d4122b851a464d 254 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 81 2.6E-14 T 28-03-2018 IPR027805 Transposase, Helix-turn-helix domain SMD44_RS00040 cb9f67a520fd099d72d4122b851a464d 254 Pfam PF13359 DDE superfamily endonuclease 102 247 5.3E-29 T 28-03-2018 IPR027806 Harbinger transposase-derived nuclease domain SMD44_RS30350 fcce23ea9d1bfcf172dde7dac372b812 217 Pfam PF02620 Uncharacterized ACR, COG1399 70 189 4.2E-33 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD SMD44_RS16175 ae458e7158fe9d09df759836e191134a 319 Pfam PF01061 ABC-2 type transporter 74 277 2.8E-16 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS21805 e03301cf5223008cc74806ad965e4d27 156 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 6 121 2.0E-9 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMD44_RS11390 0b460afd04863df9e6e9f7c88b968ffc 133 SUPERFAMILY SSF52172 7 130 4.39E-7 T 28-03-2018 IPR011006 CheY-like superfamily SMD44_RS11390 0b460afd04863df9e6e9f7c88b968ffc 133 Gene3D G3DSA:3.40.50.2300 1 133 4.6E-10 T 28-03-2018 SMD44_RS18395 4424ac6e863d1878f62ed2806dddce1c 223 SUPERFAMILY SSF52266 68 215 1.06E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS18395 4424ac6e863d1878f62ed2806dddce1c 223 SUPERFAMILY SSF52266 2 40 1.06E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS18395 4424ac6e863d1878f62ed2806dddce1c 223 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 202 8.1E-18 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMD44_RS18395 4424ac6e863d1878f62ed2806dddce1c 223 Gene3D G3DSA:3.40.50.1110 1 221 1.6E-25 T 28-03-2018 SMD44_RS11320 6f75ab59d284276473f8cce0eac0a69b 79 Gene3D G3DSA:2.30.30.380 3 46 0.067 T 28-03-2018 SMD44_RS21600 6d19078f5ea4b65f77a59906800a8a1c 340 Pfam PF13546 DDE superfamily endonuclease 20 242 1.8E-39 T 28-03-2018 SMD44_RS28340 e5df4eb7238d31f6a100b08860739752 66 Pfam PF04328 Selenoprotein, putative 7 66 2.2E-22 T 28-03-2018 IPR007423 Selenoprotein, putative SMD44_RS14180 664e02d7993d96a55afd5b8ec828939a 359 Pfam PF01757 Acyltransferase family 20 324 1.2E-22 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMD44_RS03910 ae16190ff81fe442cccb2a3b325d520b 299 Pfam PF00106 short chain dehydrogenase 2 122 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMD44_RS03910 ae16190ff81fe442cccb2a3b325d520b 299 Gene3D G3DSA:3.40.50.720 1 298 5.0E-30 T 28-03-2018 SMD44_RS03910 ae16190ff81fe442cccb2a3b325d520b 299 SUPERFAMILY SSF51735 2 221 1.14E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain SMD44_RS32700 96b9d9ca686409176a77b87ceff13587 252 Gene3D G3DSA:3.10.450.40 62 151 1.2E-13 T 28-03-2018 SMD44_RS10155 17024d96546dd16974e56544f87376bc 282 Gene3D G3DSA:1.20.5.100 239 281 8.6E-4 T 28-03-2018 SMD44_RS42235 88d584d45cc1cbb6ab16543625e01ede 205 Pfam PF01810 LysE type translocator 14 201 4.3E-29 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMD44_RS34550 e650e0bcbc7dfbae005aff6a6427dbab 45 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 23 40 5.9E-5 T 28-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 SMD44_RS28325 79b238cb427ceb98bee940acfed510a7 236 Gene3D G3DSA:3.40.190.10 3 205 3.1E-4 T 28-03-2018 SMD44_RS34315 7f988a5386ea29bdf14f5ccd0e34253a 119 Gene3D G3DSA:3.10.180.10 6 118 8.5E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS34315 7f988a5386ea29bdf14f5ccd0e34253a 119 SUPERFAMILY SSF54593 9 110 9.9E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS26835 0e7c7f625eb3ffa9fd5031d066de6584 66 Pfam PF04024 PspC domain 4 58 9.0E-19 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal SMD44_RS13250 fe9cd13595c872faaf1ce1428f67ad68 334 Pfam PF01757 Acyltransferase family 19 289 8.8E-20 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMD44_RS15350 a38df33ca553f96b87838d06d1b63be6 75 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 27 75 3.7E-10 T 28-03-2018 IPR012667 Cobalt transporter subunit CbtB, putative SMD44_RS11875 e70a75dd989194b8ac3c70cd7d2529d2 223 Pfam PF11303 Protein of unknown function (DUF3105) 95 215 4.2E-44 T 28-03-2018 IPR021454 Protein of unknown function DUF3105 SMD44_RS27415 163fee3b9cb23279ea0aeedb5bf22f34 345 Gene3D G3DSA:3.20.20.100 19 335 3.9E-83 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS27415 163fee3b9cb23279ea0aeedb5bf22f34 345 Pfam PF00248 Aldo/keto reductase family 32 330 1.7E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS27415 163fee3b9cb23279ea0aeedb5bf22f34 345 SUPERFAMILY SSF51430 17 332 1.14E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMD44_RS14960 a39f93ef2313e581c23e2df3599b5c01 325 Gene3D G3DSA:3.20.20.70 17 323 9.4E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD44_RS14960 a39f93ef2313e581c23e2df3599b5c01 325 Pfam PF00682 HMGL-like 21 301 2.7E-50 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMD44_RS14960 a39f93ef2313e581c23e2df3599b5c01 325 SUPERFAMILY SSF51569 17 322 1.61E-70 T 28-03-2018 SMD44_RS04965 4978aaf21dc45ee4a13bf04f88b56df1 81 Pfam PF10944 Protein of unknown function (DUF2630) 2 80 1.1E-32 T 28-03-2018 IPR020311 Uncharacterised protein family, Rv0898c SMD44_RS04965 4978aaf21dc45ee4a13bf04f88b56df1 81 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 5 79 2.0E-17 T 28-03-2018 IPR020311 Uncharacterised protein family, Rv0898c SMD44_RS30290 2152b52e5c1a5e04265b1f7d4aa1f2e8 145 Pfam PF12028 Protein of unknown function (DUF3515) 7 142 1.1E-27 T 28-03-2018 IPR021903 Protein of unknown function DUF3515 SMD44_RS35585 571968b8403cc669a256d754dee3dcc6 207 Pfam PF04402 Protein of unknown function (DUF541) 1 203 1.4E-40 T 28-03-2018 IPR007497 Protein of unknown function DUF541 SMD44_RS22070 2cc8045a6b8a2d525d65b375ea886e27 281 Pfam PF01061 ABC-2 type transporter 42 247 6.3E-34 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD44_RS22070 2cc8045a6b8a2d525d65b375ea886e27 281 PIRSF PIRSF006648 2 281 2.6E-74 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD44_RS33665 d93288e316479eb96bad5d084c7283ad 288 Pfam PF13673 Acetyltransferase (GNAT) domain 194 278 5.4E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 SMD44_RS33665 d93288e316479eb96bad5d084c7283ad 288 SUPERFAMILY SSF55729 116 283 4.53E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMD44_RS33665 d93288e316479eb96bad5d084c7283ad 288 Gene3D G3DSA:3.40.630.30 144 285 6.6E-15 T 28-03-2018 SMD44_RS24725 f8549d06d35e4b36618104153ae7a47d 177 SUPERFAMILY SSF51338 7 55 1.22E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS24725 f8549d06d35e4b36618104153ae7a47d 177 Gene3D G3DSA:2.30.40.10 2 56 1.9E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD44_RS07355 66b3923f1b15a4036eaf2671f780f05a 142 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 2.1E-11 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 SMD44_RS15570 6421c073bfaa2a39e2e80bbde5549f9f 273 Pfam PF06182 ABC-2 family transporter protein 47 267 4.0E-17 T 28-03-2018 IPR010390 Protein of unknown function DUF990 SMD44_RS38780 b4e30392e4455560b9176f34047d36db 404 Pfam PF04230 Polysaccharide pyruvyl transferase 13 322 3.6E-23 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase SMD44_RS38780 b4e30392e4455560b9176f34047d36db 404 Gene3D G3DSA:3.40.50.2000 225 341 2.0E-5 T 28-03-2018 SMD44_RS21415 956ef6b9688b2858bdcc42ec87e616da 256 Pfam PF05949 Bacterial protein of unknown function (DUF881) 98 253 4.0E-42 T 28-03-2018 IPR010273 Protein of unknown function DUF881 SMD44_RS42355 c9750fd410f3fc5a0316d6509f6092fd 633 Gene3D G3DSA:3.40.50.150 181 428 1.5E-23 T 28-03-2018 SMD44_RS42355 c9750fd410f3fc5a0316d6509f6092fd 633 SUPERFAMILY SSF53335 182 268 3.96E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS42355 c9750fd410f3fc5a0316d6509f6092fd 633 SUPERFAMILY SSF53335 321 532 3.96E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS38925 f750171678d1356dcba6665efa103de7 109 Gene3D G3DSA:1.20.120.20 7 93 3.7E-4 T 28-03-2018 SMD44_RS14905 5f7a8720f43e0aa7eb4ab54cfb8a02a8 490 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 404 424 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 SMD44_RS14905 5f7a8720f43e0aa7eb4ab54cfb8a02a8 490 Pfam PF00474 Sodium:solute symporter family 32 422 9.7E-38 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS11930 ac7cbac84a96ab9d2c3bc66c921deedc 501 PIRSF PIRSF006060 26 498 1.5E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS11930 ac7cbac84a96ab9d2c3bc66c921deedc 501 Pfam PF13520 Amino acid permease 40 468 7.6E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD44_RS16595 7e7d19a56dd18ef70ebbb642a808a4a9 250 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 209 244 1.3E-5 T 28-03-2018 SMD44_RS08055 4324792bb0e42a2bc8246b364efd330d 209 Pfam PF03029 Conserved hypothetical ATP binding protein 35 199 1.1E-23 T 28-03-2018 IPR004130 GPN-loop GTPase SMD44_RS08055 4324792bb0e42a2bc8246b364efd330d 209 Gene3D G3DSA:3.40.50.300 24 206 1.8E-18 T 28-03-2018 SMD44_RS08055 4324792bb0e42a2bc8246b364efd330d 209 SUPERFAMILY SSF52540 31 202 5.02E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD44_RS00885 3bfae14ec412c7abc8e94b05f7228575 164 Gene3D G3DSA:1.10.260.40 6 98 5.5E-13 T 28-03-2018 SMD44_RS00885 3bfae14ec412c7abc8e94b05f7228575 164 SUPERFAMILY SSF47413 41 85 2.38E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD44_RS08490 9d61fad9afe5144182855cac7f9e4773 130 Pfam PF02656 Domain of unknown function (DUF202) 27 91 1.1E-14 T 28-03-2018 IPR003807 Domain of unknown function DUF202 SMD44_RS06325 5240c538bdc127eed84f6ddb55aec871 364 SUPERFAMILY SSF81995 6 72 1.65E-5 T 28-03-2018 SMD44_RS24705 b09891d5a3290f0fcde15a1241f652d4 145 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 15 60 3.5E-6 T 28-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SMD44_RS06290 983d21cd90fbfcf51c24d3b8d2a7bbdc 250 Pfam PF09335 SNARE associated Golgi protein 32 160 6.5E-20 T 28-03-2018 IPR032816 SNARE associated Golgi protein SMD44_RS09530 308f6fb2a0a8ee1568f71b9e6dc7c4cc 161 Pfam PF03780 Asp23 family, cell envelope-related function 37 147 5.1E-31 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 SMD44_RS04485 79f008de26b28216d9840197eb59b472 68 Pfam PF14020 Protein of unknown function (DUF4236) 4 57 3.0E-16 T 28-03-2018 IPR025330 Domain of unknown function DUF4236 SMD44_RS41855 e9a9bd009e53e4485750de342c526575 228 Pfam PF14016 Protein of unknown function (DUF4232) 98 212 9.5E-20 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 SMD44_RS24630 a9c0a1a7ff29cf8b472adb29fc6c180c 345 Gene3D G3DSA:1.20.5.1230 5 343 3.8E-4 T 28-03-2018 SMD44_RS10325 d81b32e438b69d3372820d622d2551fb 71 Pfam PF04149 Domain of unknown function (DUF397) 10 62 1.9E-14 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS43630 db591d4b5b66737497ce4f017811d9f8 216 Pfam PF02467 Transcription factor WhiB 51 130 9.6E-11 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMD44_RS01465 6ed2dbf996ac48461a56b2bfb1c2109e 369 Pfam PF01494 FAD binding domain 3 345 1.0E-12 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 SMD44_RS01465 6ed2dbf996ac48461a56b2bfb1c2109e 369 SUPERFAMILY SSF51905 3 168 6.08E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS01465 6ed2dbf996ac48461a56b2bfb1c2109e 369 SUPERFAMILY SSF51905 273 350 6.08E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS01465 6ed2dbf996ac48461a56b2bfb1c2109e 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 8.0E-15 T 28-03-2018 SMD44_RS01465 6ed2dbf996ac48461a56b2bfb1c2109e 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 8.0E-15 T 28-03-2018 SMD44_RS01465 6ed2dbf996ac48461a56b2bfb1c2109e 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 8.0E-15 T 28-03-2018 SMD44_RS01465 6ed2dbf996ac48461a56b2bfb1c2109e 369 Gene3D G3DSA:3.50.50.60 1 354 1.4E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD44_RS03235 df735ef73264d4eef52ff7af23277ad1 140 Pfam PF03995 Peptidase inhibitor family I36 32 101 2.2E-18 T 28-03-2018 SMD44_RS03235 df735ef73264d4eef52ff7af23277ad1 140 Gene3D G3DSA:2.60.20.10 30 124 1.7E-7 T 28-03-2018 SMD44_RS24995 55ee1a749d51206e29ab503dbe8130b9 156 Gene3D G3DSA:1.10.260.40 20 100 2.2E-4 T 28-03-2018 SMD44_RS09785 8ad1ddbe86fea8955d054e8122bb4521 112 SUPERFAMILY SSF46785 14 108 1.44E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09785 8ad1ddbe86fea8955d054e8122bb4521 112 Gene3D G3DSA:1.10.10.10 2 98 4.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMD44_RS09785 8ad1ddbe86fea8955d054e8122bb4521 112 Pfam PF03551 Transcriptional regulator PadR-like family 18 89 1.8E-21 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMD44_RS18975 e078a56d05cbde7453417c2d54472788 244 SUPERFAMILY SSF53448 12 239 8.45E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS18975 e078a56d05cbde7453417c2d54472788 244 Pfam PF00483 Nucleotidyl transferase 14 240 7.9E-25 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD44_RS18975 e078a56d05cbde7453417c2d54472788 244 Gene3D G3DSA:3.90.550.10 13 243 6.8E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMD44_RS32900 26e750797fc7d8f454cbc31080188774 204 SUPERFAMILY SSF48239 8 87 8.83E-5 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS32900 26e750797fc7d8f454cbc31080188774 204 SUPERFAMILY SSF48239 165 192 8.83E-5 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD44_RS32900 26e750797fc7d8f454cbc31080188774 204 Gene3D G3DSA:1.50.10.20 1 127 0.0012 T 28-03-2018 SMD44_RS32900 26e750797fc7d8f454cbc31080188774 204 Gene3D G3DSA:1.50.10.20 128 204 0.042 T 28-03-2018 SMD44_RS09410 aa5e99d9600af9a0e8d89eb3ae98bf27 547 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 54 468 1.2E-57 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS09410 aa5e99d9600af9a0e8d89eb3ae98bf27 547 Pfam PF00474 Sodium:solute symporter family 54 469 3.4E-94 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS25305 49bec4ac03c9258bd35a0440b334b3e6 511 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 13 503 15.067 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMD44_RS25305 49bec4ac03c9258bd35a0440b334b3e6 511 Pfam PF00361 Proton-conducting membrane transporter 144 448 5.3E-52 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD44_RS28820 760fab24c9013be6f5fbc7b70cd82df6 374 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 108 266 2.0E-51 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS28820 760fab24c9013be6f5fbc7b70cd82df6 374 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 107 266 2.4E-56 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMD44_RS27855 ddc3e26a803c980ed7359db68e961a3c 232 SUPERFAMILY SSF53335 31 232 6.25E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD44_RS27855 ddc3e26a803c980ed7359db68e961a3c 232 Gene3D G3DSA:3.40.50.150 29 232 1.6E-34 T 28-03-2018 SMD44_RS27855 ddc3e26a803c980ed7359db68e961a3c 232 Pfam PF01596 O-methyltransferase 57 229 1.0E-22 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 SMD44_RS37330 10de4f49354b02257d811bf4eb79346a 254 Gene3D G3DSA:1.20.1640.10 117 245 0.013 T 28-03-2018 SMD44_RS37330 10de4f49354b02257d811bf4eb79346a 254 Gene3D G3DSA:1.20.1630.10 3 114 0.081 T 28-03-2018 SMD44_RS37330 10de4f49354b02257d811bf4eb79346a 254 Pfam PF14023 Protein of unknown function (DUF4239) 48 235 1.2E-17 T 28-03-2018 IPR025333 Protein of unknown function DUF4239 SMD44_RS38040 18302682fc403d17a7742dcb5e935838 215 Gene3D G3DSA:3.40.430.10 6 210 3.6E-38 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS38040 18302682fc403d17a7742dcb5e935838 215 SUPERFAMILY SSF53597 55 190 7.2E-25 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS38040 18302682fc403d17a7742dcb5e935838 215 SUPERFAMILY SSF53597 8 27 7.2E-25 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD44_RS38040 18302682fc403d17a7742dcb5e935838 215 Pfam PF01872 RibD C-terminal domain 10 190 4.3E-14 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD44_RS21885 0052076e9881441bef3226117c6a34de 351 Gene3D G3DSA:1.20.120.20 60 191 0.0014 T 28-03-2018 SMD44_RS21885 0052076e9881441bef3226117c6a34de 351 Pfam PF01594 AI-2E family transporter 9 312 6.9E-58 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like SMD44_RS43800 190f5da3f58de70948efa39090473bf8 511 Gene3D G3DSA:1.10.443.10 312 477 1.2E-5 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD44_RS43030 7413deb81163e28bb3e0aaca9079135c 395 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 5 336 2.6E-71 T 28-03-2018 IPR010148 CRISPR-associated protein, CT1975 SMD44_RS43030 7413deb81163e28bb3e0aaca9079135c 395 Pfam PF09344 CT1975-like protein 6 375 1.1E-95 T 28-03-2018 IPR010148 CRISPR-associated protein, CT1975 SMD44_RS12700 e4f24ec19b140e9e6459c00a10914906 143 Pfam PF11253 Protein of unknown function (DUF3052) 13 137 6.7E-55 T 28-03-2018 IPR021412 Protein of unknown function DUF3052 SMD44_RS10375 c93b68209c837baf9bcf17a9baedd3b9 157 Pfam PF12098 Protein of unknown function (DUF3574) 53 157 5.0E-35 T 28-03-2018 IPR021957 Protein of unknown function DUF3574 SMD44_RS39160 7816b0ea1f46e1c74d2a4df133b93b05 208 Pfam PF07681 DoxX 46 145 8.5E-7 T 28-03-2018 IPR032808 DoxX family SMD44_RS41970 82bb4c26e39d8ebb3cd81018d8fc0bd8 160 Pfam PF14087 Domain of unknown function (DUF4267) 36 141 2.8E-21 T 28-03-2018 IPR025363 Protein of unknown function DUF4267 SMD44_RS23160 094d1bb8b36c5c230cfb064fec0ecd79 53 Pfam PF13783 Domain of unknown function (DUF4177) 4 50 2.2E-6 T 28-03-2018 IPR025234 Protein of unknown function DUF4177 SMD44_RS30970 6cd2be94707e0a449b1ee7b5cf9db75b 148 Gene3D G3DSA:1.10.287.1060 53 135 7.9E-5 T 28-03-2018 SMD44_RS15440 a32c727c1a3624610a7ad5c264e4f99f 285 Gene3D G3DSA:3.90.850.10 19 284 6.7E-78 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS15440 a32c727c1a3624610a7ad5c264e4f99f 285 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 281 6.5E-68 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS15440 a32c727c1a3624610a7ad5c264e4f99f 285 SUPERFAMILY SSF56529 69 282 1.09E-74 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD44_RS18565 370204d8ccf5e24a80884763e0b37b2b 312 Pfam PF11228 Protein of unknown function (DUF3027) 42 267 6.3E-83 T 28-03-2018 IPR021391 Protein of unknown function DUF3027 SMD44_RS15635 6fd075aab6249fe0df54e1ed35558db7 416 Pfam PF02378 Phosphotransferase system, EIIC 27 337 2.4E-70 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMD44_RS17485 ffa0c7183c0287f76adde8e4fad4b28f 896 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 79 273 2.0E-5 T 28-03-2018 SMD44_RS20855 51d5b4f216bc7051d5e6b4e7e2903ab9 464 Pfam PF07907 YibE/F-like protein 177 414 2.1E-73 T 28-03-2018 IPR012507 YibE/F-like SMD44_RS00675 1806fd488998266a984c9bdb248a5a2b 196 Gene3D G3DSA:3.30.460.10 5 183 7.7E-45 T 28-03-2018 SMD44_RS00675 1806fd488998266a984c9bdb248a5a2b 196 Pfam PF04229 GrpB protein 10 169 1.9E-37 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase SMD44_RS00675 1806fd488998266a984c9bdb248a5a2b 196 SUPERFAMILY SSF81301 12 181 3.92E-35 T 28-03-2018 SMD44_RS17900 e0d95962fbd8e299c0d8b5861211c5f6 127 Gene3D G3DSA:3.10.180.10 1 119 1.1E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS17900 e0d95962fbd8e299c0d8b5861211c5f6 127 SUPERFAMILY SSF54593 3 117 3.12E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS00065 4efd1cad6fdc1dbff18e6949f042a365 288 Pfam PF13704 Glycosyl transferase family 2 16 108 3.9E-6 T 28-03-2018 SMD44_RS23780 95b12587a37cca76c419e5e431ac3c17 171 Pfam PF03703 Bacterial PH domain 82 160 5.1E-15 T 28-03-2018 IPR005182 Domain of unknown function DUF304 SMD44_RS22080 72c9093ac3da0b959421ce7cd5d05ea1 69 Pfam PF04149 Domain of unknown function (DUF397) 11 62 1.5E-20 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS23555 3a70a8aedf51e50b4f7ffa2e3dd3ac90 333 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 114 321 3.0E-67 T 28-03-2018 SMD44_RS23555 3a70a8aedf51e50b4f7ffa2e3dd3ac90 333 Pfam PF10979 Protein of unknown function (DUF2786) 112 151 2.1E-16 T 28-03-2018 IPR024498 Domain of unknown function DUF2786 SMD44_RS25660 c3cd7af5275306e48ec300fd38164018 437 Pfam PF09594 Glycosyltransferase family 87 74 291 6.5E-15 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD44_RS31055 83242ab7ce44d2169825bc0070ed4062 186 Pfam PF10756 Bacterial PH domain 91 150 6.4E-5 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 SMD44_RS11125 75b55cf0695e488cd78e8220f963da58 209 Pfam PF13548 Domain of unknown function (DUF4126) 6 172 2.8E-47 T 28-03-2018 IPR025196 Domain of unknown function DUF4126 SMD44_RS32420 f9071b6c34e6e6879d509ab60d159b34 256 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 9 232 3.1E-40 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain SMD44_RS18215 0ccaf7ce34507ae31a05e4abc4752f5f 163 Gene3D G3DSA:2.60.40.10 73 162 1.0E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS43085 5b5cd1e2cd5bf3903a8ef2779679adc3 297 Pfam PF00482 Type II secretion system (T2SS), protein F 108 232 3.5E-8 T 28-03-2018 IPR018076 Type II secretion system F domain SMD44_RS12785 a4b6adb9c1da2096651a941289a7788b 164 Pfam PF11343 Protein of unknown function (DUF3145) 6 162 1.8E-73 T 28-03-2018 IPR021491 Protein of unknown function DUF3145 SMD44_RS19150 071ceced360e3cb80c73649f5ca444cc 278 Pfam PF13349 Putative adhesin 23 246 2.1E-10 T 28-03-2018 IPR025164 Putative adhesin SMD44_RS20150 929ddcd500eac68636595bbf0b42408b 251 Pfam PF13796 Putative sensor 57 249 3.8E-39 T 28-03-2018 IPR025828 Putative sensor domain SMD44_RS22925 6d80a64929c4e7f2bd9101e633ea7690 149 Pfam PF07681 DoxX 62 112 1.3E-5 T 28-03-2018 IPR032808 DoxX family SMD44_RS37275 313f32b44692fdece4cffd6b9972b3f3 224 Pfam PF13490 Putative zinc-finger 11 37 1.9E-5 T 28-03-2018 IPR027383 Putative zinc-finger SMD44_RS23815 05f7023845669e4108895546fbb94e19 403 Pfam PF01212 Beta-eliminating lyase 80 311 2.0E-24 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 SMD44_RS23815 05f7023845669e4108895546fbb94e19 403 SUPERFAMILY SSF53383 78 339 3.57E-59 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMD44_RS23815 05f7023845669e4108895546fbb94e19 403 Gene3D G3DSA:3.40.640.10 43 291 9.0E-26 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD44_RS23000 5cbc63613003794010f347d39020f55a 211 Gene3D G3DSA:3.40.50.300 1 186 7.1E-8 T 28-03-2018 SMD44_RS24695 ac04b849cf462f7ae0be214a82a126da 144 Pfam PF07811 TadE-like protein 19 61 2.2E-12 T 28-03-2018 IPR012495 TadE-like SMD44_RS11265 f9a12b96e995e4e2bfa25d2729c05a90 158 Pfam PF17230 Family of unknown function (DUF5304) 17 158 6.8E-71 T 28-03-2018 IPR035183 Protein of unknown function DUF5304 SMD44_RS15710 fb54935d68d6eb64dbe2d6af624ed9dc 104 Gene3D G3DSA:3.10.180.10 1 96 7.2E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD44_RS37045 b484cec7d38b8066c200bea3142fbe43 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 312 5.8E-44 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS37045 b484cec7d38b8066c200bea3142fbe43 321 Gene3D G3DSA:1.10.3470.10 28 318 1.0E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS09160 9250784fc9fd7a9e209d1e74852c1774 453 Pfam PF02687 FtsX-like permease family 94 185 6.4E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS09160 9250784fc9fd7a9e209d1e74852c1774 453 Pfam PF02687 FtsX-like permease family 356 436 3.7E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMD44_RS24885 5123b3407e89a4ace258cf041ca701a4 644 Pfam PF06152 Phage minor capsid protein 2 5 353 1.4E-66 T 28-03-2018 IPR009319 Bacteriophage A118, Gp4, minor capsid GO:0005198|GO:0019028 SMD44_RS42105 2a2c884136997c2b4ebe44c38008266b 147 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 19 135 4.4E-22 T 28-03-2018 IPR018727 Protein of unknown function DUF2267 SMD44_RS27325 6ca8036080886d136c6b35753cabd712 444 Pfam PF01566 Natural resistance-associated macrophage protein 46 413 4.9E-36 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMD44_RS28330 81fd20eae1485ed6cf60e0dce48e464b 540 Pfam PF00474 Sodium:solute symporter family 44 410 4.6E-19 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD44_RS19890 d41bd8196824cd2459b9ea895c9d7eac 280 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 10 215 6.0E-20 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 SMD44_RS03260 0ba4492d448f5c3005a9aefabe0c6bfd 123 Pfam PF04343 Protein of unknown function, DUF488 11 120 3.3E-32 T 28-03-2018 IPR007438 Protein of unknown function DUF488 SMD44_RS33000 2ed9dae2c23736bfab956d3a1f8d9d8e 289 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 253 273 3.5E-6 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 SMD44_RS43060 fd43c285f59703b361b94f0a67c92409 151 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 19 66 6.0E-6 T 28-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SMD44_RS00845 fd4e5927831874160203acf02e6752d1 225 Pfam PF14016 Protein of unknown function (DUF4232) 89 216 8.5E-20 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 SMD44_RS29295 b02d3695395dbf3f2ebdbab1b61bc9ab 73 Pfam PF04149 Domain of unknown function (DUF397) 15 70 6.9E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS19020 338679e5e861e14ff1947ebf19c31f16 249 SUPERFAMILY SSF110087 41 163 5.75E-7 T 28-03-2018 IPR007410 Copper chaperone PCuAC SMD44_RS10570 4696624d925a71b357691c49f715f0c8 237 Pfam PF04402 Protein of unknown function (DUF541) 21 230 1.8E-36 T 28-03-2018 IPR007497 Protein of unknown function DUF541 SMD44_RS39755 c7cc9a162a18aa006e4f98de66a6296a 379 Pfam PF00487 Fatty acid desaturase 124 372 5.2E-39 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SMD44_RS35045 03cdb6f42b584ededf37ddd24f9cb747 126 Gene3D G3DSA:3.40.30.10 10 123 3.5E-4 T 28-03-2018 SMD44_RS15470 afe3e84c3c10bef7f7d54c6bc93dc646 68 Pfam PF11755 Protein of unknown function (DUF3311) 10 62 4.1E-14 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 SMD44_RS35050 3b88492932e24b1b8f5683efc4438e6c 167 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 163 2.5E-61 T 28-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger SMD44_RS16785 288cb52738161144b8df90b1267f6733 164 Pfam PF04977 Septum formation initiator 49 127 3.2E-16 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SMD44_RS16780 d583042746b92c4bd79b14e9c8c56b43 174 Pfam PF04417 Protein of unknown function (DUF501) 36 155 2.0E-36 T 28-03-2018 IPR007511 Protein of unknown function DUF501 SMD44_RS21160 dd66d13fc7180dc4150020906e653a0d 248 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 128 246 3.1E-41 T 28-03-2018 IPR021949 Domain of unknown function DUF3566. transmembrane SMD44_RS24870 dbe682e86dfe0e3c7ec4ead42d28d498 285 SUPERFAMILY SSF56563 41 283 1.44E-9 T 28-03-2018 SMD44_RS15365 432e4242fdbf6a91b5b3d29ec49cd4ba 181 Gene3D G3DSA:2.60.40.10 7 118 1.6E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold SMD44_RS15690 785f3853460a9440364a02574e6c16ab 202 Pfam PF09438 Domain of unknown function (DUF2017) 9 200 1.0E-58 T 28-03-2018 IPR018561 Domain of unknown function DUF2017 SMD44_RS20755 109c18dbddd21ed7cb8a84a3e0decd9c 293 Pfam PF12679 ABC-2 family transporter protein 85 278 2.8E-7 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMD44_RS36070 760a5cb7efd74c9aafe6d2eced56bbf8 234 Pfam PF03591 AzlC protein 30 161 7.8E-30 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease SMD44_RS27525 3cf3c80f074164e84cff278e8d325244 180 Pfam PF14030 Protein of unknown function (DUF4245) 7 169 2.5E-52 T 28-03-2018 IPR025339 Protein of unknown function DUF4245 SMD44_RS41135 e11f117ce8aae97f7bd89f201c6d0fbd 103 SUPERFAMILY SSF50118 3 103 6.1E-5 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMD44_RS32915 1834e72b6792b069ccffab5eb3fe4c51 63 Gene3D G3DSA:3.40.50.1580 1 62 1.1E-8 T 28-03-2018 SMD44_RS40400 9c01a868df3f513842be95161ea34bcd 378 Gene3D G3DSA:1.10.3470.10 24 370 2.0E-25 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMD44_RS40400 9c01a868df3f513842be95161ea34bcd 378 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 179 9.2E-20 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS40400 9c01a868df3f513842be95161ea34bcd 378 Pfam PF02653 Branched-chain amino acid transport system / permease component 209 366 3.0E-28 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD44_RS28650 145a402c2aa5af00d41e9e22b827b7c6 281 Pfam PF13672 Protein phosphatase 2C 29 244 2.3E-5 T 28-03-2018 SMD44_RS24490 6ecea415383281f68b2399b660342083 104 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 99 1.7E-13 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD SMD44_RS29090 a6a260406049e9194b54a9290d684b13 226 Pfam PF13761 Domain of unknown function (DUF4166) 16 201 1.2E-61 T 28-03-2018 IPR025311 Domain of unknown function DUF4166 SMD44_RS26300 377a625fadc1ff22a2c87deeb12b236c 75 Pfam PF04149 Domain of unknown function (DUF397) 22 71 2.7E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS26300 377a625fadc1ff22a2c87deeb12b236c 75 Pfam PF04149 Domain of unknown function (DUF397) 4 21 4.0E-6 T 28-03-2018 IPR007278 Domain of unknown function DUF397 SMD44_RS23770 04e94d0dbe14f9ed1d44e26eb88fd6e3 406 Gene3D G3DSA:1.20.5.340 35 368 1.9E-5 T 28-03-2018 SMD44_RS33485 937ea737b3a93856d7c7a26b3c90df15 211 Gene3D G3DSA:3.90.70.10 53 211 1.4E-10 T 28-03-2018 SMD44_RS38450 2ae3df9280cc6a4280cdb3f3fc5dc688 277 SUPERFAMILY SSF81995 3 64 4.18E-6 T 28-03-2018 SMD44_RS12920 56ac741a5ed67ddb5be46ad07a0e35ed 433 Pfam PF01757 Acyltransferase family 35 391 9.2E-26 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMD44_RS24745 c967581979e01f6885d558873678d9b7 129 Pfam PF03793 PASTA domain 12 73 1.2E-6 T 28-03-2018 IPR005543 PASTA domain SMD44_RS32570 141793feed6c0f99124a8e669f5fd008 554 Gene3D G3DSA:1.20.120.570 170 370 1.4E-4 T 28-03-2018 SMD44_RS18750 38fd3d8b197faf83b7f610da80343237 88 Pfam PF13223 Protein of unknown function (DUF4031) 4 77 3.4E-32 T 28-03-2018 IPR025109 Domain of unknown function DUF4031 SMD44_RS33320 7f3face74151015ee7f824b5d3587bae 195 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 133 191 2.4E-17 T 28-03-2018 SMD44_RS04730 e119e9ec475fa1dc100cac60bca6f572 269 Gene3D G3DSA:1.20.120.330 76 233 1.3E-5 T 28-03-2018 SMD44_RS19330 b56efd3ee7db8b287d601346cab05d1c 402 Pfam PF11209 Protein of unknown function (DUF2993) 86 277 1.3E-30 T 28-03-2018 IPR021373 Protein of unknown function DUF2993 SMD44_RS29085 8e00ffde00434918d533a710bb595a3b 255 SUPERFAMILY SSF55961 22 155 2.95E-5 T 28-03-2018 SMD44_RS07775 eb56162a1dcc4309ee6b03fa57e5fe0b 331 Pfam PF01758 Sodium Bile acid symporter family 63 239 1.7E-42 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SMD44_RS23665 6525061c0c6f8459df58a3981f6fbb9a 403 Pfam PF09335 SNARE associated Golgi protein 41 167 1.7E-22 T 28-03-2018 IPR032816 SNARE associated Golgi protein SMD44_RS02220 e60408399e62587084657249be466def 210 Pfam PF01955 Adenosylcobinamide amidohydrolase 1 178 7.0E-47 T 28-03-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ SMD44_RS36050 fbc30ccbf0c3947707525807f6d3252f 209 SUPERFAMILY SSF53850 26 176 5.32E-5 T 28-03-2018 SMD44_RS05885 519e0e907d8a535bce27e17d5091c2b6 82 Pfam PF16945 Putative lactococcus lactis phage r1t holin 3 65 6.4E-22 T 28-03-2018 IPR020109 Holin, r1t-type SMD44_RS31680 ed924f14edb3639c9a5c6de23e106102 354 Pfam PF11268 Protein of unknown function (DUF3071) 1 168 3.7E-55 T 28-03-2018 IPR021421 Protein of unknown function DUF3071 SMD44_RS33180 db008f3ebf9182c1be185c8e8c762417 141 Gene3D G3DSA:2.60.20.10 20 137 1.9E-8 T 28-03-2018 SMD44_RS31565 94b37239831233877b909d05c493c326 180 Pfam PF04341 Protein of unknown function, DUF485 76 162 2.9E-26 T 28-03-2018 IPR007436 Protein of unknown function DUF485 SMD44_RS30145 839c2fc64cbfc99e598f4aea150d2e32 64 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 4 62 9.6E-17 T 28-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit SMD44_RS03515 7bbd8479217e9f87b20401311af34b49 318 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 16 247 1.3E-53 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 SMD44_RS03550 30de1a38c49493f8805ae23fc4b63cec 272 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 117 262 8.4E-7 T 28-03-2018 IPR024534 Domain of unknown function DUF2220 SMD44_RS19935 c94235ba2906a55265edc4a4feae9267 85 Pfam PF11273 Protein of unknown function (DUF3073) 2 62 2.2E-21 T 28-03-2018 IPR021426 Protein of unknown function DUF3073 SMD44_RS00310 6ceca955865a0fc133933f4d02a9c268 345 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 37 329 3.3E-68 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF SMD44_RS10815 d0918016c86252f002bf2a5c5a260504 63 Pfam PF14013 MT0933-like antitoxin protein 4 51 7.0E-21 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 SMD44_RS09545 4899c29319077aa0b08be12a99797f05 86 Gene3D G3DSA:1.10.10.10 29 82 0.0049 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain