locus-tag	class	description
B7C62_RS00055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7C62_RS00070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7C62_RS00075	COG0395	ABC-type sugar transport system, permease component
B7C62_RS00080	COG1175	transmembrane transport
B7C62_RS00115	COG2890	protein-(glutamine-N5) methyltransferase activity
B7C62_RS00125	COG0142	geranyltranstransferase activity
B7C62_RS00145	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B7C62_RS00210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B7C62_RS00230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B7C62_RS00235	COG1846	Transcriptional regulator
B7C62_RS00240	COG1764	response to oxidative stress
B7C62_RS00250	COG0789	Transcriptional regulator
B7C62_RS00275	COG1064	alcohol dehydrogenase
B7C62_RS00285	COG0702	epimerase
B7C62_RS00305	COG0745	RESPONSE REGULATOR receiver
B7C62_RS00310	COG0642	Histidine kinase
B7C62_RS00330	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
B7C62_RS00335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B7C62_RS00340	COG0366	Alpha amylase catalytic
B7C62_RS00345	COG0395	ABC-type sugar transport system, permease component
B7C62_RS00350	COG1175	transmembrane transport
B7C62_RS00355	COG1653	transport
B7C62_RS00385	COG1349	DNA-binding transcription factor activity
B7C62_RS00390	COG1105	Belongs to the carbohydrate kinase PfkB family
B7C62_RS00405	COG0681	Belongs to the peptidase S26 family
B7C62_RS00460	COG0254	rRNA binding
B7C62_RS00465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B7C62_RS00480	COG0510	thiamine kinase activity
B7C62_RS00500	COG1309	transcriptional regulator
B7C62_RS00535	COG1024	Enoyl-CoA hydratase
B7C62_RS00565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7C62_RS00570	COG0765	amino acid transport
B7C62_RS00575	COG1126	abc transporter atp-binding protein
B7C62_RS00605	COG2070	2-Nitropropane dioxygenase
B7C62_RS00610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7C62_RS00625	COG0515	serine threonine protein kinase
B7C62_RS00640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7C62_RS00645	COG2124	cytochrome p450
B7C62_RS00675	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS00680	COG2813	Specifically methylates the guanine in position
B7C62_RS00690	COG2356	endonuclease I
B7C62_RS00695	COG2066	Belongs to the glutaminase family
B7C62_RS00695	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B7C62_RS00710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7C62_RS00725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7C62_RS00730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B7C62_RS00735	COG2080	2 iron, 2 sulfur cluster binding
B7C62_RS00785	COG2365	Tyrosine phosphatase family
B7C62_RS00810	COG1120	ATPase activity
B7C62_RS00815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7C62_RS00825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS00835	COG0477	Major facilitator Superfamily
B7C62_RS00840	COG2382	esterase
B7C62_RS00845	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS00855	COG1169	isochorismate synthase
B7C62_RS00860	COG1021	2,3-dihydroxybenzoate-AMP ligase
B7C62_RS00865	COG1535	isochorismatase
B7C62_RS00865	COG3433	isochorismatase activity
B7C62_RS00870	COG1535	isochorismatase
B7C62_RS00870	COG3433	isochorismatase activity
B7C62_RS00875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B7C62_RS00895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B7C62_RS00930	COG3845	ABC transporter
B7C62_RS00960	COG1470	cell adhesion involved in biofilm formation
B7C62_RS00985	COG1132	(ABC) transporter
B7C62_RS01000	COG1063	alcohol dehydrogenase
B7C62_RS01020	COG1349	DNA-binding transcription factor activity
B7C62_RS01065	COG2382	esterase
B7C62_RS01070	COG1132	(ABC) transporter
B7C62_RS01080	COG1132	(ABC) transporter
B7C62_RS01085	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B7C62_RS01090	COG1120	ATPase activity
B7C62_RS01095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS01100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS01105	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B7C62_RS01120	COG2957	Belongs to the agmatine deiminase family
B7C62_RS01125	COG0596	Alpha beta hydrolase
B7C62_RS01140	COG1840	ABC-type Fe3 transport system, periplasmic component
B7C62_RS01145	COG1178	ABC-type Fe3 transport system permease component
B7C62_RS01150	COG3842	ATPase activity
B7C62_RS01165	COG0385	Bile acid
B7C62_RS01185	COG1902	pentaerythritol trinitrate reductase activity
B7C62_RS01185	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7C62_RS01205	COG0640	Transcriptional regulator
B7C62_RS01210	COG2376	Dihydroxyacetone kinase
B7C62_RS01215	COG1461	Dihydroxyacetone kinase
B7C62_RS01230	COG0488	(ABC) transporter
B7C62_RS01260	COG1191	sigma factor activity
B7C62_RS01270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7C62_RS01290	COG1120	ATPase activity
B7C62_RS01295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS01320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7C62_RS01335	COG1695	Transcriptional regulator
B7C62_RS01360	COG1295	ribonuclease BN
B7C62_RS01360	COG1959	2 iron, 2 sulfur cluster binding
B7C62_RS01390	COG1120	ATPase activity
B7C62_RS01395	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS01400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS01435	COG1335	isochorismatase
B7C62_RS01440	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B7C62_RS01450	COG1874	Beta-galactosidase
B7C62_RS01450	COG0366	Alpha amylase catalytic
B7C62_RS01455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7C62_RS01460	COG0587	DNA-directed DNA polymerase activity
B7C62_RS01475	COG1716	ATPase activity
B7C62_RS01475	COG0842	Transport permease protein
B7C62_RS01475	COG1131	(ABC) transporter
B7C62_RS01490	COG2801	Transposase and inactivated derivatives
B7C62_RS01490	COG3415	Transposase
B7C62_RS01500	COG1733	regulation of RNA biosynthetic process
B7C62_RS01515	COG0640	Transcriptional regulator
B7C62_RS01520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7C62_RS01550	COG0328	RNA-DNA hybrid ribonuclease activity
B7C62_RS01560	COG1132	(ABC) transporter
B7C62_RS01580	COG2207	Transcriptional regulator
B7C62_RS01580	COG4753	response regulator
B7C62_RS01585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS01590	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS01595	COG1120	ATPase activity
B7C62_RS01605	COG1132	(ABC) transporter
B7C62_RS01610	COG1132	(ABC) transporter
B7C62_RS01695	COG0464	growth
B7C62_RS01705	COG1349	DNA-binding transcription factor activity
B7C62_RS01720	COG0702	epimerase
B7C62_RS01745	COG1940	carbohydrate kinase activity
B7C62_RS01750	COG2223	nitrite transmembrane transporter activity
B7C62_RS01780	COG0445	tRNA wobble uridine modification
B7C62_RS01795	COG1660	Displays ATPase and GTPase activities
B7C62_RS01800	COG1940	carbohydrate kinase activity
B7C62_RS01820	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B7C62_RS01860	COG0584	glycerophosphoryl diester phosphodiesterase
B7C62_RS01865	COG0456	acetyltransferase
B7C62_RS01880	COG0671	phosphoesterase, PA-phosphatase related
B7C62_RS01920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B7C62_RS01925	COG2971	BadF BadG BcrA BcrD
B7C62_RS01935	COG2706	6-phosphogluconolactonase activity
B7C62_RS01955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7C62_RS01960	COG0515	serine threonine protein kinase
B7C62_RS01960	COG2815	serine threonine protein kinase
B7C62_RS01965	COG0667	Aldo Keto reductase
B7C62_RS02050	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B7C62_RS02055	COG0531	amino acid
B7C62_RS02060	COG2186	Transcriptional regulator
B7C62_RS02065	COG0174	glutamine synthetase
B7C62_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS02095	COG0297	glycogen (starch) synthase activity
B7C62_RS02105	COG4981	capsule polysaccharide biosynthetic process
B7C62_RS02125	COG2835	tetraacyldisaccharide 4'-kinase activity
B7C62_RS02135	COG0745	RESPONSE REGULATOR receiver
B7C62_RS02220	COG1357	PFAM Pentapeptide repeats (8 copies)
B7C62_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS02235	COG1982	Orn Lys Arg decarboxylase major
B7C62_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS02320	COG2124	cytochrome p450
B7C62_RS02335	COG1335	isochorismatase
B7C62_RS02370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B7C62_RS02370	COG0617	tRNA 3'-terminal CCA addition
B7C62_RS02370	COG0517	IMP dehydrogenase activity
B7C62_RS02395	COG3629	intracellular signal transduction
B7C62_RS02395	COG3903	Transcriptional regulator
B7C62_RS02410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS02425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS02430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS02430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS02435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS02450	COG4865	methylaspartate mutase activity
B7C62_RS02455	COG0017	Asparaginyl-tRNA synthetase
B7C62_RS02460	COG0069	glutamate synthase activity
B7C62_RS02480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7C62_RS02485	COG0542	response to heat
B7C62_RS02555	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B7C62_RS02575	COG2197	response regulator
B7C62_RS02625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7C62_RS02630	COG1116	anion transmembrane transporter activity
B7C62_RS02640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS02645	COG2072	flavoprotein involved in K transport
B7C62_RS02655	COG1132	(ABC) transporter
B7C62_RS02660	COG1846	Transcriptional regulator
B7C62_RS02675	COG1132	(ABC) transporter
B7C62_RS02680	COG1132	(ABC) transporter
B7C62_RS02690	COG0791	NLP P60 protein
B7C62_RS02705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7C62_RS02705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7C62_RS02720	COG1252	NADH dehydrogenase
B7C62_RS02725	COG1793	dna ligase
B7C62_RS02740	COG1946	Acyl-CoA thioesterase
B7C62_RS02755	COG0386	Belongs to the glutathione peroxidase family
B7C62_RS02760	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS02770	COG0242	peptide deformylase activity
B7C62_RS02780	COG3442	glutamine amidotransferase
B7C62_RS02785	COG0205	6-phosphofructokinase activity
B7C62_RS02800	COG0204	Acyl-transferase
B7C62_RS02810	COG0829	nickel cation binding
B7C62_RS02815	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B7C62_RS02825	COG0804	urea catabolic process
B7C62_RS02830	COG0832	Belongs to the urease beta subunit family
B7C62_RS02835	COG0831	urea catabolic process
B7C62_RS02845	COG0740	serine-type endopeptidase activity
B7C62_RS02855	COG0791	NLP P60 protein
B7C62_RS02860	COG1280	lysine exporter protein (LysE YggA)
B7C62_RS02865	COG0583	DNA-binding transcription factor activity
B7C62_RS02890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B7C62_RS02895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7C62_RS02900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B7C62_RS02905	COG2226	methyltransferase
B7C62_RS02920	COG0456	acetyltransferase
B7C62_RS02940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7C62_RS02945	COG3663	DNA glycosylase
B7C62_RS02960	COG4585	Histidine kinase
B7C62_RS02965	COG2197	response regulator
B7C62_RS02970	COG1940	carbohydrate kinase activity
B7C62_RS02975	COG2188	Transcriptional regulator
B7C62_RS02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7C62_RS03015	COG0626	cystathionine gamma-synthase activity
B7C62_RS03040	COG1522	sequence-specific DNA binding
B7C62_RS03045	COG0419	ATPase involved in DNA repair
B7C62_RS03050	COG0420	3'-5' exonuclease activity
B7C62_RS03055	COG1739	Uncharacterized protein family UPF0029
B7C62_RS03060	COG1832	CoA-binding protein
B7C62_RS03100	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7C62_RS03115	COG1968	undecaprenyl-diphosphatase activity
B7C62_RS03150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B7C62_RS03160	COG2318	DinB family
B7C62_RS03175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B7C62_RS03210	COG2318	DinB family
B7C62_RS03230	COG0697	spore germination
B7C62_RS03270	COG1695	Transcriptional regulator
B7C62_RS03315	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7C62_RS03315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7C62_RS03325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7C62_RS03345	COG1716	ATPase activity
B7C62_RS03365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7C62_RS03395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7C62_RS03405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7C62_RS03420	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B7C62_RS03450	COG2018	Roadblock/LC7 domain
B7C62_RS03520	COG2364	Membrane
B7C62_RS03530	COG2270	Major facilitator Superfamily
B7C62_RS03540	COG3030	protein affecting phage T7 exclusion by the F plasmid
B7C62_RS03545	COG1216	Glycosyl transferase, family 2
B7C62_RS03570	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS03580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS03585	COG1917	Cupin 2, conserved barrel domain protein
B7C62_RS03595	COG1045	serine acetyltransferase
B7C62_RS03615	COG2814	Major facilitator Superfamily
B7C62_RS03635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7C62_RS03660	COG0252	asparaginase activity
B7C62_RS03735	COG0464	growth
B7C62_RS03745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B7C62_RS03750	COG0140	phosphoribosyl-ATP diphosphatase activity
B7C62_RS03755	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B7C62_RS03765	COG3201	nicotinamide mononucleotide transporter
B7C62_RS03785	COG1940	carbohydrate kinase activity
B7C62_RS03790	COG0738	Major facilitator superfamily
B7C62_RS03795	COG2233	PERMEase
B7C62_RS03810	COG2197	response regulator
B7C62_RS03825	COG4585	Histidine kinase
B7C62_RS03835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7C62_RS03855	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS03870	COG2390	Transcriptional regulator
B7C62_RS03875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7C62_RS03885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B7C62_RS03900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B7C62_RS03910	COG1758	RNA polymerase activity
B7C62_RS03925	COG0284	orotidine-5'-phosphate decarboxylase activity
B7C62_RS03930	COG0167	dihydroorotate dehydrogenase activity
B7C62_RS03935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7C62_RS03940	COG0505	Belongs to the CarA family
B7C62_RS03950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7C62_RS03955	COG0540	Belongs to the ATCase OTCase family
B7C62_RS03960	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B7C62_RS03970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7C62_RS03975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B7C62_RS03980	COG0006	proline dipeptidase activity
B7C62_RS03990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B7C62_RS03995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B7C62_RS04000	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B7C62_RS04005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B7C62_RS04020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B7C62_RS04025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B7C62_RS04045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B7C62_RS04065	COG1131	(ABC) transporter
B7C62_RS04075	COG4585	Histidine kinase
B7C62_RS04080	COG2197	response regulator
B7C62_RS04085	COG0124	histidyl-tRNA synthetase
B7C62_RS04100	COG1196	nuclear chromosome segregation
B7C62_RS04105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7C62_RS04115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B7C62_RS04120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7C62_RS04125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7C62_RS04135	COG2255	four-way junction helicase activity
B7C62_RS04140	COG0632	four-way junction helicase activity
B7C62_RS04145	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B7C62_RS04150	COG0217	transcriptional regulatory protein
B7C62_RS04155	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B7C62_RS04160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B7C62_RS04170	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS04175	COG1560	Kdo2-lipid A biosynthetic process
B7C62_RS04180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7C62_RS04205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B7C62_RS04220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7C62_RS04275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7C62_RS04330	COG1648	precorrin-2 dehydrogenase activity
B7C62_RS04330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7C62_RS04335	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7C62_RS04350	COG1464	Belongs to the NlpA lipoprotein family
B7C62_RS04355	COG2011	ABC-type metal ion transport system permease component
B7C62_RS04405	COG0477	Major facilitator Superfamily
B7C62_RS04415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7C62_RS04420	COG3973	AAA domain
B7C62_RS04430	COG0165	Argininosuccinate lyase
B7C62_RS04435	COG0137	argininosuccinate synthase activity
B7C62_RS04445	COG1438	arginine binding
B7C62_RS04450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7C62_RS04455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B7C62_RS04460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B7C62_RS04465	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B7C62_RS04560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7C62_RS04600	COG0697	spore germination
B7C62_RS04610	COG1649	PFAM Uncharacterised BCR, COG1649
B7C62_RS04620	COG1051	belongs to the nudix hydrolase family
B7C62_RS04630	COG0072	phenylalanine-tRNA ligase activity
B7C62_RS04630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7C62_RS04635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B7C62_RS04640	COG5002	protein histidine kinase activity
B7C62_RS04645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7C62_RS04650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B7C62_RS04655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B7C62_RS04660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B7C62_RS04725	COG4176	ABC-type proline glycine betaine transport system permease component
B7C62_RS04730	COG4175	Glycine betaine
B7C62_RS04730	COG0517	IMP dehydrogenase activity
B7C62_RS04735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7C62_RS04780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7C62_RS04785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7C62_RS04820	COG0805	protein transport
B7C62_RS04825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7C62_RS04845	COG2378	regulation of single-species biofilm formation
B7C62_RS04860	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B7C62_RS04870	COG1609	Transcriptional regulator
B7C62_RS04875	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B7C62_RS04880	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B7C62_RS04895	COG4122	O-methyltransferase activity
B7C62_RS04900	COG1222	aaa ATPase
B7C62_RS04925	COG1994	Peptidase M50
B7C62_RS04925	COG0517	IMP dehydrogenase activity
B7C62_RS04935	COG2197	response regulator
B7C62_RS04940	COG4166	transmembrane transport
B7C62_RS04950	COG0646	methionine synthase
B7C62_RS04950	COG1410	methionine synthase
B7C62_RS04955	COG1414	Transcriptional regulator
B7C62_RS04960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B7C62_RS04965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7C62_RS04970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7C62_RS04975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS04985	COG0215	cysteine-tRNA ligase activity
B7C62_RS05005	COG0598	Magnesium transport protein CorA
B7C62_RS05015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS05020	COG0667	Aldo Keto reductase
B7C62_RS05050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7C62_RS05060	COG0564	pseudouridine synthase activity
B7C62_RS05075	COG2186	Transcriptional regulator
B7C62_RS05080	COG3265	gluconokinase activity
B7C62_RS05100	COG3573	Dehydrogenase
B7C62_RS05105	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B7C62_RS05110	COG2149	membrane
B7C62_RS05130	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS05135	COG4935	Belongs to the peptidase S8 family
B7C62_RS05135	COG2234	aminopeptidase activity
B7C62_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS05150	COG3876	Protein conserved in bacteria
B7C62_RS05195	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7C62_RS05225	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS05235	COG0242	peptide deformylase activity
B7C62_RS05270	COG0494	nUDIX hydrolase
B7C62_RS05275	COG0697	spore germination
B7C62_RS05280	COG2326	polyphosphate kinase activity
B7C62_RS05300	COG2851	Citrate transporter
B7C62_RS05305	COG0243	molybdopterin cofactor binding
B7C62_RS05310	COG1309	transcriptional regulator
B7C62_RS05315	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B7C62_RS05325	COG2188	Transcriptional regulator
B7C62_RS05335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7C62_RS05345	COG2755	lipolytic protein G-D-S-L family
B7C62_RS05355	COG1725	Transcriptional regulator
B7C62_RS05375	COG0346	lactoylglutathione lyase activity
B7C62_RS05410	COG3903	Transcriptional regulator
B7C62_RS05410	COG3629	intracellular signal transduction
B7C62_RS05420	COG0641	radical SAM
B7C62_RS05450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS05455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS05460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7C62_RS05480	COG0765	amino acid transport
B7C62_RS05495	COG1799	cell septum assembly
B7C62_RS05500	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS05505	COG0477	Major facilitator Superfamily
B7C62_RS05510	COG0671	phosphoesterase, PA-phosphatase related
B7C62_RS05530	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS05545	COG1160	GTP binding
B7C62_RS05555	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B7C62_RS05580	COG3541	Predicted nucleotidyltransferase
B7C62_RS05590	COG0494	nUDIX hydrolase
B7C62_RS05605	COG1187	pseudouridine synthase activity
B7C62_RS05610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7C62_RS05615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7C62_RS05630	COG0686	Belongs to the AlaDH PNT family
B7C62_RS05640	COG0494	nUDIX hydrolase
B7C62_RS05645	COG0504	CTP synthase activity
B7C62_RS05650	COG3387	PFAM Glycoside hydrolase 15-related
B7C62_RS05660	COG0789	Transcriptional regulator
B7C62_RS05670	COG3119	arylsulfatase activity
B7C62_RS05675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7C62_RS05685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7C62_RS05715	COG0297	glycogen (starch) synthase activity
B7C62_RS05720	COG0497	DNA recombination
B7C62_RS05725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7C62_RS05745	COG1120	ATPase activity
B7C62_RS05750	COG0647	UMP catabolic process
B7C62_RS05785	COG2094	Belongs to the DNA glycosylase MPG family
B7C62_RS05795	COG1881	PFAM PEBP family protein
B7C62_RS05820	COG1119	ATPase activity
B7C62_RS05835	COG2197	response regulator
B7C62_RS05840	COG4585	Histidine kinase
B7C62_RS05850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B7C62_RS05860	COG1716	ATPase activity
B7C62_RS05860	COG1131	(ABC) transporter
B7C62_RS05860	COG0842	Transport permease protein
B7C62_RS05865	COG3830	Belongs to the UPF0237 family
B7C62_RS05865	COG0560	Phosphoserine phosphatase
B7C62_RS05885	COG2186	Transcriptional regulator
B7C62_RS05895	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B7C62_RS05900	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS05915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B7C62_RS05935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7C62_RS05940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7C62_RS05950	COG1404	Belongs to the peptidase S8 family
B7C62_RS05955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7C62_RS05975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7C62_RS05990	COG3387	PFAM Glycoside hydrolase 15-related
B7C62_RS06040	COG0488	(ABC) transporter
B7C62_RS06060	COG0235	Class ii aldolase
B7C62_RS06075	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B7C62_RS06080	COG1492	cobalamin metabolic process
B7C62_RS06095	COG1797	cobyrinic acid a,c-diamide synthase activity
B7C62_RS06120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7C62_RS06150	COG1902	pentaerythritol trinitrate reductase activity
B7C62_RS06155	COG1846	Transcriptional regulator
B7C62_RS06170	COG2124	cytochrome p450
B7C62_RS06215	COG0768	penicillin binding
B7C62_RS06225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS06235	COG0431	NADPH-dependent FMN reductase
B7C62_RS06250	COG0583	DNA-binding transcription factor activity
B7C62_RS06255	COG2801	Transposase and inactivated derivatives
B7C62_RS06255	COG3415	Transposase
B7C62_RS06290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7C62_RS06295	COG2171	N-acyltransferase activity
B7C62_RS06300	COG3226	Transcriptional regulator
B7C62_RS06315	COG2151	metal-sulfur cluster biosynthetic enzyme
B7C62_RS06320	COG0822	iron-sulfur transferase activity
B7C62_RS06325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7C62_RS06330	COG0396	ATPase activity
B7C62_RS06340	COG0719	Fe-S assembly protein
B7C62_RS06375	COG0109	protoheme IX farnesyltransferase activity
B7C62_RS06385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7C62_RS06400	COG0363	glucosamine-6-phosphate deaminase activity
B7C62_RS06410	COG4195	phage-related replication protein
B7C62_RS06425	COG0166	Belongs to the GPI family
B7C62_RS06435	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7C62_RS06440	COG0149	triose-phosphate isomerase activity
B7C62_RS06445	COG0126	phosphoglycerate kinase activity
B7C62_RS06450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7C62_RS06455	COG1481	regulation of sporulation
B7C62_RS06460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B7C62_RS06465	COG1660	Displays ATPase and GTPase activities
B7C62_RS06470	COG0322	excinuclease ABC activity
B7C62_RS06495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7C62_RS06510	COG0596	Alpha beta hydrolase
B7C62_RS06530	COG0556	nucleotide-excision repair
B7C62_RS06540	COG0584	glycerophosphoryl diester phosphodiesterase
B7C62_RS06545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7C62_RS06550	COG2814	Major facilitator Superfamily
B7C62_RS06560	COG2313	pseudouridylate synthase activity
B7C62_RS06580	COG0436	Aminotransferase
B7C62_RS06600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7C62_RS06605	COG0330	HflC and HflK could
B7C62_RS06625	COG0237	dephospho-CoA kinase activity
B7C62_RS06645	COG2226	methyltransferase
B7C62_RS06650	COG1643	Atp-dependent helicase
B7C62_RS06680	COG2050	protein possibly involved in aromatic compounds catabolism
B7C62_RS06745	COG0659	secondary active sulfate transmembrane transporter activity
B7C62_RS06755	COG2824	Alkylphosphonate utilization operon protein PhnA
B7C62_RS06775	COG0287	Prephenate dehydrogenase
B7C62_RS06775	COG1605	Chorismate mutase
B7C62_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS06820	COG1024	Enoyl-CoA hydratase
B7C62_RS06845	COG1278	Cold shock
B7C62_RS06850	COG0183	Belongs to the thiolase family
B7C62_RS06855	COG1309	transcriptional regulator
B7C62_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS06865	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS06870	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS06890	COG0705	Rhomboid family
B7C62_RS06900	COG0069	glutamate synthase activity
B7C62_RS06900	COG0067	glutamate synthase
B7C62_RS06900	COG0070	glutamate synthase
B7C62_RS06910	COG1397	ADP-ribosylglycohydrolase
B7C62_RS06930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7C62_RS06935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7C62_RS06945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B7C62_RS06955	COG0159	tryptophan synthase activity
B7C62_RS06960	COG0133	tryptophan synthase activity
B7C62_RS06970	COG0134	indole-3-glycerol-phosphate synthase activity
B7C62_RS06990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7C62_RS06995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B7C62_RS07005	COG2508	Transcriptional regulator
B7C62_RS07015	COG0107	imidazoleglycerol-phosphate synthase activity
B7C62_RS07020	COG0251	oxidation-reduction process
B7C62_RS07025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B7C62_RS07030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7C62_RS07035	COG0131	Imidazoleglycerol-phosphate dehydratase
B7C62_RS07040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7C62_RS07045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B7C62_RS07060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7C62_RS07065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7C62_RS07085	COG1432	Conserved Protein
B7C62_RS07095	COG0587	DNA-directed DNA polymerase activity
B7C62_RS07145	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B7C62_RS07155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B7C62_RS07160	COG3599	regulation of cell shape
B7C62_RS07170	COG1799	cell septum assembly
B7C62_RS07175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B7C62_RS07200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B7C62_RS07210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B7C62_RS07215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7C62_RS07225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7C62_RS07230	COG0768	penicillin binding
B7C62_RS07240	COG0275	rRNA processing
B7C62_RS07250	COG0714	Associated with various cellular activities
B7C62_RS07280	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B7C62_RS07285	COG1511	domain protein
B7C62_RS07290	COG1309	transcriptional regulator
B7C62_RS07315	COG0352	thiamine-phosphate diphosphorylase activity
B7C62_RS07335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7C62_RS07335	COG2022	thiamine diphosphate biosynthetic process
B7C62_RS07345	COG2022	thiamine diphosphate biosynthetic process
B7C62_RS07350	COG2815	serine threonine protein kinase
B7C62_RS07350	COG0515	serine threonine protein kinase
B7C62_RS07355	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B7C62_RS07360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B7C62_RS07365	COG2193	ferroxidase activity
B7C62_RS07375	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B7C62_RS07385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7C62_RS07395	COG4585	Histidine kinase
B7C62_RS07420	COG1940	carbohydrate kinase activity
B7C62_RS07430	COG0003	Pfam Anion-transporting ATPase
B7C62_RS07495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7C62_RS07500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7C62_RS07505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B7C62_RS07510	COG0723	plastoquinol--plastocyanin reductase activity
B7C62_RS07515	COG2010	Cytochrome c
B7C62_RS07520	COG1845	cytochrome c oxidase, subunit III
B7C62_RS07530	COG1376	ErfK ybiS ycfS ynhG family protein
B7C62_RS07540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7C62_RS07545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B7C62_RS07550	COG1104	cysteine desulfurase activity
B7C62_RS07555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7C62_RS07575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B7C62_RS07590	COG2197	response regulator
B7C62_RS07620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7C62_RS07635	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7C62_RS07640	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B7C62_RS07640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B7C62_RS07655	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B7C62_RS07660	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B7C62_RS07665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7C62_RS07680	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B7C62_RS07700	COG1090	epimerase
B7C62_RS07715	COG0321	lipoyl(octanoyl) transferase activity
B7C62_RS07720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7C62_RS07760	COG1846	Transcriptional regulator
B7C62_RS07775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7C62_RS07780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7C62_RS07805	COG0745	RESPONSE REGULATOR receiver
B7C62_RS07815	COG2197	response regulator
B7C62_RS07875	COG0366	Alpha amylase catalytic
B7C62_RS07880	COG0395	ABC-type sugar transport system, permease component
B7C62_RS07895	COG1609	Transcriptional regulator
B7C62_RS07905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B7C62_RS07910	COG2890	protein-(glutamine-N5) methyltransferase activity
B7C62_RS07995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7C62_RS08005	COG0174	glutamine synthetase
B7C62_RS08020	COG2132	Multicopper oxidase
B7C62_RS08025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B7C62_RS08025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7C62_RS08030	COG2814	Major facilitator Superfamily
B7C62_RS08045	COG0477	Major facilitator Superfamily
B7C62_RS08050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B7C62_RS08070	COG1994	Peptidase M50
B7C62_RS08135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS08140	COG1120	ATPase activity
B7C62_RS08160	COG1834	amidinotransferase
B7C62_RS08180	COG2814	Major facilitator Superfamily
B7C62_RS08190	COG3540	Alkaline phosphatase
B7C62_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS08205	COG0384	phenazine biosynthesis protein PhzF
B7C62_RS08255	COG3022	response to hydroperoxide
B7C62_RS08260	COG0800	Aldolase
B7C62_RS08280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7C62_RS08285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7C62_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS08310	COG2030	dehydratase
B7C62_RS08320	COG0183	Belongs to the thiolase family
B7C62_RS08325	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS08335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7C62_RS08355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS08380	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS08385	COG1309	transcriptional regulator
B7C62_RS08450	COG3209	COG3209 Rhs family protein
B7C62_RS08495	COG3845	ABC transporter
B7C62_RS08505	COG0183	Belongs to the thiolase family
B7C62_RS08510	COG2124	cytochrome p450
B7C62_RS08625	COG1358	cellular component organization or biogenesis
B7C62_RS08670	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B7C62_RS08680	COG0477	Major facilitator Superfamily
B7C62_RS08685	COG1309	transcriptional regulator
B7C62_RS08700	COG4585	Histidine kinase
B7C62_RS08705	COG2197	response regulator
B7C62_RS08720	COG0667	Aldo Keto reductase
B7C62_RS08725	COG0789	Transcriptional regulator
B7C62_RS08780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7C62_RS08785	COG1741	Belongs to the pirin family
B7C62_RS08810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7C62_RS08815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7C62_RS08820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7C62_RS08845	COG1309	transcriptional regulator
B7C62_RS08870	COG1764	response to oxidative stress
B7C62_RS08875	COG2130	NADP-dependent
B7C62_RS08905	COG1522	sequence-specific DNA binding
B7C62_RS08920	COG1733	regulation of RNA biosynthetic process
B7C62_RS08925	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS08930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B7C62_RS08930	COG0825	malonyl-CoA metabolic process
B7C62_RS08965	COG2197	response regulator
B7C62_RS08975	COG0583	DNA-binding transcription factor activity
B7C62_RS09000	COG1070	Carbohydrate kinase
B7C62_RS09015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7C62_RS09025	COG0358	DNA primase activity
B7C62_RS09030	COG2226	methyltransferase
B7C62_RS09040	COG0477	Major facilitator Superfamily
B7C62_RS09050	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B7C62_RS09060	COG2949	membrane
B7C62_RS09065	COG0243	molybdopterin cofactor binding
B7C62_RS09115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7C62_RS09120	COG2146	nitrite reductase [NAD(P)H] activity
B7C62_RS09120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7C62_RS09125	COG2146	nitrite reductase [NAD(P)H] activity
B7C62_RS09125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7C62_RS09145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7C62_RS09145	COG0574	Belongs to the PEP-utilizing enzyme family
B7C62_RS09155	COG3842	ATPase activity
B7C62_RS09160	COG2011	ABC-type metal ion transport system permease component
B7C62_RS09175	COG2188	Transcriptional regulator
B7C62_RS09195	COG0583	DNA-binding transcription factor activity
B7C62_RS09205	COG2066	Belongs to the glutaminase family
B7C62_RS09270	COG0423	glycine-tRNA ligase activity
B7C62_RS09275	COG3443	Belongs to the bacterial solute-binding protein 9 family
B7C62_RS09275	COG0803	Belongs to the bacterial solute-binding protein 9 family
B7C62_RS09280	COG1121	(ABC) transporter
B7C62_RS09285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7C62_RS09295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7C62_RS09300	COG1381	Involved in DNA repair and RecF pathway recombination
B7C62_RS09310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7C62_RS09325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B7C62_RS09340	COG2315	Protein conserved in bacteria
B7C62_RS09350	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B7C62_RS09360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7C62_RS09370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7C62_RS09375	COG1234	tRNA 3'-trailer cleavage
B7C62_RS09380	COG0537	adenosine 5'-monophosphoramidase activity
B7C62_RS09395	COG0484	heat shock protein binding
B7C62_RS09400	COG1420	regulation of RNA biosynthetic process
B7C62_RS09425	COG1022	Amp-dependent synthetase and ligase
B7C62_RS09430	COG0481	GTPase activity
B7C62_RS09435	COG0268	Binds directly to 16S ribosomal RNA
B7C62_RS09485	COG1555	photosystem II stabilization
B7C62_RS09490	COG1307	EDD domain protein, DegV family
B7C62_RS09500	COG0495	leucyl-tRNA aminoacylation
B7C62_RS09510	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7C62_RS09535	COG0588	phosphoglycerate mutase activity
B7C62_RS09540	COG0799	negative regulation of ribosome biogenesis
B7C62_RS09550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B7C62_RS09555	COG0501	Belongs to the peptidase M48B family
B7C62_RS09570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B7C62_RS09580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B7C62_RS09585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7C62_RS09605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B7C62_RS09610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B7C62_RS09615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B7C62_RS09650	COG0673	inositol 2-dehydrogenase activity
B7C62_RS09655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7C62_RS09660	COG1530	ribonuclease E activity
B7C62_RS09685	COG0772	Belongs to the SEDS family
B7C62_RS09690	COG0768	penicillin binding
B7C62_RS09705	COG1077	Cell shape determining protein MreB Mrl
B7C62_RS09710	COG0105	UTP biosynthetic process
B7C62_RS09720	COG0285	dihydrofolate synthase activity
B7C62_RS09725	COG0525	valine-tRNA ligase activity
B7C62_RS09735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B7C62_RS09740	COG0740	serine-type endopeptidase activity
B7C62_RS09745	COG0740	serine-type endopeptidase activity
B7C62_RS09750	COG0544	peptidyl-prolyl cis-trans isomerase activity
B7C62_RS09770	COG3594	Acyltransferase
B7C62_RS09780	COG0475	glutathione-regulated potassium exporter activity
B7C62_RS09790	COG4552	Acetyltransferase involved in intracellular survival and related
B7C62_RS09805	COG1113	amino acid transport
B7C62_RS09810	COG1268	BioY protein
B7C62_RS09815	COG1113	amino acid transport
B7C62_RS09820	COG1113	amino acid transport
B7C62_RS09830	COG0584	glycerophosphoryl diester phosphodiesterase
B7C62_RS09835	COG0783	Belongs to the Dps family
B7C62_RS09845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7C62_RS09850	COG0640	Transcriptional regulator
B7C62_RS09865	COG0110	maltose O-acetyltransferase activity
B7C62_RS09875	COG2318	DinB family
B7C62_RS09910	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS09915	COG1231	oxidoreductase activity
B7C62_RS09930	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7C62_RS09980	COG4266	Belongs to the allantoicase family
B7C62_RS10000	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B7C62_RS10000	COG3291	Pkd domain containing protein
B7C62_RS10010	COG0668	transmembrane transport
B7C62_RS10015	COG1940	carbohydrate kinase activity
B7C62_RS10025	COG1175	transmembrane transport
B7C62_RS10030	COG0395	ABC-type sugar transport system, permease component
B7C62_RS10035	COG1486	melibiose metabolic process
B7C62_RS10050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7C62_RS10085	COG2346	COG2346, Truncated hemoglobins
B7C62_RS10100	COG1136	(ABC) transporter
B7C62_RS10100	COG0577	efflux transmembrane transporter activity
B7C62_RS10125	COG0629	single-stranded DNA binding
B7C62_RS10145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7C62_RS10170	COG1131	(ABC) transporter
B7C62_RS10190	COG3962	Belongs to the TPP enzyme family
B7C62_RS10195	COG3718	enzyme involved in inositol metabolism
B7C62_RS10210	COG1082	Xylose isomerase domain protein TIM barrel
B7C62_RS10225	COG2409	Drug exporters of the RND superfamily
B7C62_RS10250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7C62_RS10260	COG0477	Major facilitator Superfamily
B7C62_RS10305	COG0148	phosphopyruvate hydratase activity
B7C62_RS10330	COG0673	inositol 2-dehydrogenase activity
B7C62_RS10335	COG1609	Transcriptional regulator
B7C62_RS10360	COG0515	serine threonine protein kinase
B7C62_RS10390	COG1404	Belongs to the peptidase S8 family
B7C62_RS10405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B7C62_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS10440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7C62_RS10445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7C62_RS10450	COG1472	Belongs to the glycosyl hydrolase 3 family
B7C62_RS10485	COG3960	tartronate-semialdehyde synthase activity
B7C62_RS10550	COG1946	Acyl-CoA thioesterase
B7C62_RS10575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B7C62_RS10575	COG2755	lipolytic protein G-D-S-L family
B7C62_RS10580	COG2311	Membrane
B7C62_RS10590	COG1309	transcriptional regulator
B7C62_RS10595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7C62_RS10610	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS10620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B7C62_RS10645	COG3537	Alpha-1,2-mannosidase
B7C62_RS10650	COG1733	regulation of RNA biosynthetic process
B7C62_RS10670	COG0076	glutamate decarboxylase activity
B7C62_RS10675	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B7C62_RS10705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7C62_RS10710	COG0589	response to stress
B7C62_RS10715	COG4977	sequence-specific DNA binding
B7C62_RS10750	COG0395	ABC-type sugar transport system, permease component
B7C62_RS10765	COG2985	domain, Protein
B7C62_RS10810	COG0588	phosphoglycerate mutase activity
B7C62_RS10860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS10875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7C62_RS10880	COG0765	amino acid transport
B7C62_RS10885	COG0765	amino acid transport
B7C62_RS10890	COG1126	abc transporter atp-binding protein
B7C62_RS10910	COG3397	chitin binding
B7C62_RS10970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7C62_RS10975	COG2188	Transcriptional regulator
B7C62_RS11015	COG0673	inositol 2-dehydrogenase activity
B7C62_RS11020	COG4702	Belongs to the UPF0303 family
B7C62_RS11030	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
B7C62_RS11030	COG0706	membrane insertase activity
B7C62_RS11040	COG3764	Sortase (surface protein transpeptidase)
B7C62_RS11070	COG1215	transferase activity, transferring glycosyl groups
B7C62_RS11080	COG0745	RESPONSE REGULATOR receiver
B7C62_RS11130	COG3135	benzoate transporter
B7C62_RS11135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7C62_RS11150	COG2175	clavaminate synthase activity
B7C62_RS11155	COG0667	Aldo Keto reductase
B7C62_RS11160	COG2267	carboxylic ester hydrolase activity
B7C62_RS11170	COG2733	membrane
B7C62_RS11200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7C62_RS11225	COG0477	Major facilitator Superfamily
B7C62_RS11235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B7C62_RS11245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B7C62_RS11250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7C62_RS11255	COG1263	PTS System
B7C62_RS11260	COG1263	PTS System
B7C62_RS11265	COG1234	tRNA 3'-trailer cleavage
B7C62_RS11290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS11305	COG1113	amino acid transport
B7C62_RS11315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B7C62_RS11325	COG1335	isochorismatase
B7C62_RS11360	COG0277	FAD linked oxidase domain protein
B7C62_RS11370	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B7C62_RS11380	COG1174	glycine betaine transport
B7C62_RS11390	COG1174	glycine betaine transport
B7C62_RS11395	COG1732	Glycine betaine
B7C62_RS11415	COG3480	Lon protease (S16) C-terminal proteolytic domain
B7C62_RS11430	COG3654	unkown
B7C62_RS11470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7C62_RS11485	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B7C62_RS11490	COG0395	ABC-type sugar transport system, permease component
B7C62_RS11510	COG1678	Uncharacterized ACR, COG1678
B7C62_RS11515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7C62_RS11520	COG0776	regulation of translation
B7C62_RS11530	COG3973	AAA domain
B7C62_RS11560	COG2223	nitrite transmembrane transporter activity
B7C62_RS11585	COG0583	DNA-binding transcription factor activity
B7C62_RS11595	COG1120	ATPase activity
B7C62_RS11600	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS11605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS11625	COG1132	(ABC) transporter
B7C62_RS11630	COG1132	(ABC) transporter
B7C62_RS11680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B7C62_RS11685	COG0793	Belongs to the peptidase S41A family
B7C62_RS11695	COG2177	Part of the ABC transporter FtsEX involved in
B7C62_RS11700	COG2884	Cell division ATP-binding protein ftsE
B7C62_RS11715	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B7C62_RS11720	COG0515	serine threonine protein kinase
B7C62_RS11725	COG0515	serine threonine protein kinase
B7C62_RS11735	COG1653	transport
B7C62_RS11740	COG1175	transmembrane transport
B7C62_RS11745	COG0395	ABC-type sugar transport system, permease component
B7C62_RS11750	COG1216	Glycosyl transferase, family 2
B7C62_RS11750	COG1442	glycosyl transferase family 8
B7C62_RS11755	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS11760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7C62_RS11765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7C62_RS11775	COG2226	methyltransferase
B7C62_RS11775	COG1073	alpha beta
B7C62_RS11780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7C62_RS11785	COG1216	Glycosyl transferase, family 2
B7C62_RS11795	COG1309	transcriptional regulator
B7C62_RS11810	COG2902	Dehydrogenase
B7C62_RS11835	COG0653	protein targeting
B7C62_RS11850	COG2197	response regulator
B7C62_RS11855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7C62_RS11865	COG0823	Involved in the tonB-independent uptake of proteins
B7C62_RS11870	COG5000	phosphorelay sensor kinase activity
B7C62_RS11870	COG5002	protein histidine kinase activity
B7C62_RS11875	COG0745	RESPONSE REGULATOR receiver
B7C62_RS11880	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B7C62_RS11900	COG0714	Associated with various cellular activities
B7C62_RS11945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B7C62_RS11955	COG1482	cell wall glycoprotein biosynthetic process
B7C62_RS11965	COG2835	tetraacyldisaccharide 4'-kinase activity
B7C62_RS11970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7C62_RS12010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B7C62_RS12015	COG0778	Nitroreductase
B7C62_RS12015	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B7C62_RS12040	COG1316	TRANSCRIPTIONal
B7C62_RS12045	COG1316	TRANSCRIPTIONal
B7C62_RS12060	COG1316	TRANSCRIPTIONal
B7C62_RS12065	COG1607	acyl-coa hydrolase
B7C62_RS12070	COG1316	TRANSCRIPTIONal
B7C62_RS12105	COG2755	lipolytic protein G-D-S-L family
B7C62_RS12155	COG2205	protein histidine kinase activity
B7C62_RS12160	COG0745	RESPONSE REGULATOR receiver
B7C62_RS12170	COG3104	oligopeptide transport
B7C62_RS12205	COG1191	sigma factor activity
B7C62_RS12210	COG1228	amidohydrolase
B7C62_RS12220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7C62_RS12225	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B7C62_RS12230	COG0531	amino acid
B7C62_RS12275	COG2755	lipolytic protein G-D-S-L family
B7C62_RS12280	COG0183	Belongs to the thiolase family
B7C62_RS12305	COG0577	efflux transmembrane transporter activity
B7C62_RS12305	COG1136	(ABC) transporter
B7C62_RS12310	COG1136	(ABC) transporter
B7C62_RS12310	COG0577	efflux transmembrane transporter activity
B7C62_RS12315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7C62_RS12320	COG1252	NADH dehydrogenase
B7C62_RS12330	COG2211	Major facilitator Superfamily
B7C62_RS12340	COG2188	Transcriptional regulator
B7C62_RS12370	COG0148	phosphopyruvate hydratase activity
B7C62_RS12400	COG0515	serine threonine protein kinase
B7C62_RS12400	COG2815	serine threonine protein kinase
B7C62_RS12490	COG1994	Peptidase M50
B7C62_RS12520	COG3903	Transcriptional regulator
B7C62_RS12520	COG3629	intracellular signal transduction
B7C62_RS12530	COG0577	efflux transmembrane transporter activity
B7C62_RS12535	COG1136	(ABC) transporter
B7C62_RS12535	COG0577	efflux transmembrane transporter activity
B7C62_RS12545	COG2814	Major facilitator Superfamily
B7C62_RS12555	COG0346	lactoylglutathione lyase activity
B7C62_RS12615	COG4585	Histidine kinase
B7C62_RS12625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B7C62_RS12630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7C62_RS12635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B7C62_RS12640	COG0193	aminoacyl-tRNA hydrolase activity
B7C62_RS12650	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B7C62_RS12670	COG4106	trans-aconitate 2-methyltransferase activity
B7C62_RS12675	COG1846	Transcriptional regulator
B7C62_RS12680	COG2197	response regulator
B7C62_RS12690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B7C62_RS12725	COG0488	(ABC) transporter
B7C62_RS12730	COG2161	toxin-antitoxin pair type II binding
B7C62_RS12750	COG2813	Specifically methylates the guanine in position
B7C62_RS12755	COG2318	DinB family
B7C62_RS12760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B7C62_RS12765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B7C62_RS12775	COG0084	hydrolase, TatD family'
B7C62_RS12800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7C62_RS12815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7C62_RS12850	COG0778	Nitroreductase
B7C62_RS12850	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B7C62_RS12875	COG0442	prolyl-tRNA aminoacylation
B7C62_RS12910	COG0181	hydroxymethylbilane synthase activity
B7C62_RS12920	COG0113	porphobilinogen synthase activity
B7C62_RS12925	COG0583	DNA-binding transcription factor activity
B7C62_RS12930	COG2814	Major facilitator Superfamily
B7C62_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS12945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7C62_RS12950	COG1122	ATPase activity
B7C62_RS12960	COG0310	cobalt ion transport
B7C62_RS12970	COG2409	Drug exporters of the RND superfamily
B7C62_RS12980	COG0793	Belongs to the peptidase S41A family
B7C62_RS12980	COG4946	Tricorn protease homolog
B7C62_RS13005	COG1051	belongs to the nudix hydrolase family
B7C62_RS13030	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS13040	COG2072	flavoprotein involved in K transport
B7C62_RS13050	COG0708	Exodeoxyribonuclease III
B7C62_RS13055	COG1247	-acetyltransferase
B7C62_RS13085	COG0829	nickel cation binding
B7C62_RS13090	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B7C62_RS13095	COG0830	nickel cation binding
B7C62_RS13100	COG0804	urea catabolic process
B7C62_RS13105	COG0832	Belongs to the urease beta subunit family
B7C62_RS13145	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7C62_RS13150	COG0315	cyclic pyranopterin monophosphate synthase activity
B7C62_RS13160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7C62_RS13165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7C62_RS13190	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B7C62_RS13200	COG1970	mechanosensitive ion channel activity
B7C62_RS13220	COG0437	4 iron, 4 sulfur cluster binding
B7C62_RS13225	COG0243	molybdopterin cofactor binding
B7C62_RS13250	COG0477	Major facilitator Superfamily
B7C62_RS13270	COG3384	dioxygenase
B7C62_RS13275	COG1846	Transcriptional regulator
B7C62_RS13295	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS13315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7C62_RS13330	COG2301	Belongs to the HpcH HpaI aldolase family
B7C62_RS13360	COG0154	amidase activity
B7C62_RS13365	COG2814	Major facilitator Superfamily
B7C62_RS13380	COG0006	proline dipeptidase activity
B7C62_RS13385	COG0006	proline dipeptidase activity
B7C62_RS13390	COG2301	Belongs to the HpcH HpaI aldolase family
B7C62_RS13400	COG3594	Acyltransferase
B7C62_RS13470	COG1686	Belongs to the peptidase S11 family
B7C62_RS13540	COG3655	Transcriptional regulator
B7C62_RS13575	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B7C62_RS13590	COG0768	penicillin binding
B7C62_RS13645	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B7C62_RS13675	COG1309	transcriptional regulator
B7C62_RS13680	COG0655	NAD(P)H dehydrogenase (quinone) activity
B7C62_RS13685	COG2070	2-Nitropropane dioxygenase
B7C62_RS13845	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS13860	COG1309	transcriptional regulator
B7C62_RS13885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS13890	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS13910	COG1301	dicarboxylic acid transport
B7C62_RS13925	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B7C62_RS13935	COG0163	prenyltransferase activity
B7C62_RS13945	COG0109	protoheme IX farnesyltransferase activity
B7C62_RS13950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B7C62_RS13960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7C62_RS13965	COG1333	cytochrome c biogenesis protein
B7C62_RS13970	COG0785	Cytochrome C biogenesis protein
B7C62_RS13985	COG2382	esterase
B7C62_RS13990	COG0406	alpha-ribazole phosphatase activity
B7C62_RS13995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B7C62_RS14040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7C62_RS14045	COG1690	Belongs to the RtcB family
B7C62_RS14080	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B7C62_RS14085	COG0018	arginyl-trna synthetase
B7C62_RS14095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7C62_RS14135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7C62_RS14160	COG0113	porphobilinogen synthase activity
B7C62_RS14165	COG1648	precorrin-2 dehydrogenase activity
B7C62_RS14165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7C62_RS14170	COG0181	hydroxymethylbilane synthase activity
B7C62_RS14175	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B7C62_RS14180	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B7C62_RS14230	COG0123	including yeast histone deacetylase and acetoin utilization protein
B7C62_RS14235	COG2223	nitrite transmembrane transporter activity
B7C62_RS14240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7C62_RS14265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7C62_RS14275	COG1129	ABC transporter
B7C62_RS14275	COG0842	Transport permease protein
B7C62_RS14285	COG4991	sh3 domain protein
B7C62_RS14295	COG0129	dihydroxy-acid dehydratase activity
B7C62_RS14300	COG1309	transcriptional regulator
B7C62_RS14305	COG1082	Xylose isomerase domain protein TIM barrel
B7C62_RS14310	COG0248	Ppx GppA phosphatase
B7C62_RS14330	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B7C62_RS14340	COG1194	a g-specific adenine glycosylase
B7C62_RS14345	COG1595	DNA-templated transcription, initiation
B7C62_RS14355	COG0745	RESPONSE REGULATOR receiver
B7C62_RS14360	COG2205	protein histidine kinase activity
B7C62_RS14365	COG0739	heme binding
B7C62_RS14400	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B7C62_RS14420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B7C62_RS14430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B7C62_RS14435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B7C62_RS14455	COG1660	Displays ATPase and GTPase activities
B7C62_RS14460	COG2197	response regulator
B7C62_RS14475	COG0649	NAD binding
B7C62_RS14485	COG1732	Glycine betaine
B7C62_RS14490	COG1174	glycine betaine transport
B7C62_RS14500	COG1125	glycine betaine transport
B7C62_RS14500	COG0517	IMP dehydrogenase activity
B7C62_RS14510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B7C62_RS14510	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B7C62_RS14530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B7C62_RS14545	COG0302	gtp cyclohydrolase
B7C62_RS14560	COG0037	tRNA processing
B7C62_RS14570	COG2027	D-alanyl-D-alanine carboxypeptidase
B7C62_RS14575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7C62_RS14585	COG0586	Pfam SNARE associated Golgi protein
B7C62_RS14590	COG0393	Putative heavy-metal-binding
B7C62_RS14600	COG0655	NAD(P)H dehydrogenase (quinone) activity
B7C62_RS14605	COG0076	glutamate decarboxylase activity
B7C62_RS14640	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS14715	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B7C62_RS14745	COG3629	intracellular signal transduction
B7C62_RS14745	COG3903	Transcriptional regulator
B7C62_RS14760	COG1132	(ABC) transporter
B7C62_RS14765	COG1132	(ABC) transporter
B7C62_RS14790	COG1509	lysine 2,3-aminomutase activity
B7C62_RS14805	COG2175	clavaminate synthase activity
B7C62_RS14815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7C62_RS14820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7C62_RS14825	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7C62_RS14835	COG2936	dipeptidyl-peptidase activity
B7C62_RS14845	COG3173	Aminoglycoside phosphotransferase
B7C62_RS14875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7C62_RS14880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7C62_RS14885	COG1754	DNA topoisomerase type I activity
B7C62_RS14885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7C62_RS14900	COG2890	protein-(glutamine-N5) methyltransferase activity
B7C62_RS14915	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B7C62_RS14925	COG1366	Belongs to the anti-sigma-factor antagonist family
B7C62_RS14930	COG1205	dead DEAH box helicase
B7C62_RS14930	COG1111	helicase
B7C62_RS14990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7C62_RS14995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7C62_RS15005	COG2267	carboxylic ester hydrolase activity
B7C62_RS15035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7C62_RS15055	COG0003	Pfam Anion-transporting ATPase
B7C62_RS15070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B7C62_RS15080	COG1408	metallophosphoesterase
B7C62_RS15115	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
B7C62_RS15115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7C62_RS15135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7C62_RS15140	COG2755	lipolytic protein G-D-S-L family
B7C62_RS15150	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B7C62_RS15170	COG1595	DNA-templated transcription, initiation
B7C62_RS15190	COG0702	epimerase
B7C62_RS15200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B7C62_RS15205	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B7C62_RS15220	COG1802	Transcriptional regulator
B7C62_RS15225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7C62_RS15230	COG0693	protein deglycase activity
B7C62_RS15240	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7C62_RS15240	COG0515	serine threonine protein kinase
B7C62_RS15245	COG0738	Major facilitator superfamily
B7C62_RS15260	COG3226	Transcriptional regulator
B7C62_RS15290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7C62_RS15345	COG0592	DNA-directed DNA polymerase activity
B7C62_RS15355	COG4249	Peptidase C14 caspase catalytic subunit p20
B7C62_RS15355	COG2319	Wd-40 repeat
B7C62_RS15380	COG1136	(ABC) transporter
B7C62_RS15380	COG0577	efflux transmembrane transporter activity
B7C62_RS15395	COG0667	Aldo Keto reductase
B7C62_RS15435	COG0590	tRNA wobble adenosine to inosine editing
B7C62_RS15445	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7C62_RS15450	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B7C62_RS15475	COG2197	response regulator
B7C62_RS15495	COG3844	kynureninase activity
B7C62_RS15510	COG0477	Major facilitator Superfamily
B7C62_RS15515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B7C62_RS15520	COG0191	fructose-bisphosphate aldolase activity
B7C62_RS15525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B7C62_RS15540	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B7C62_RS15595	COG0542	response to heat
B7C62_RS15635	COG0789	Transcriptional regulator
B7C62_RS15640	COG0484	heat shock protein binding
B7C62_RS15645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B7C62_RS15650	COG0443	Heat shock 70 kDa protein
B7C62_RS15660	COG0247	lactate metabolic process
B7C62_RS15660	COG2181	nitrate reductase activity
B7C62_RS15675	COG0717	Belongs to the dCTP deaminase family
B7C62_RS15765	COG4585	Histidine kinase
B7C62_RS15790	COG4133	protoheme IX ABC transporter activity
B7C62_RS15800	COG2197	response regulator
B7C62_RS15820	COG0477	Major facilitator Superfamily
B7C62_RS15840	COG3629	intracellular signal transduction
B7C62_RS15840	COG3903	Transcriptional regulator
B7C62_RS15845	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS15865	COG0604	alcohol dehydrogenase
B7C62_RS15865	COG3321	synthase
B7C62_RS15870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7C62_RS15915	COG2124	cytochrome p450
B7C62_RS15920	COG2211	Major facilitator Superfamily
B7C62_RS15945	COG1309	transcriptional regulator
B7C62_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS15965	COG1686	Belongs to the peptidase S11 family
B7C62_RS15970	COG2205	protein histidine kinase activity
B7C62_RS15975	COG0745	RESPONSE REGULATOR receiver
B7C62_RS15990	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS16015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7C62_RS16025	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B7C62_RS16040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7C62_RS16040	COG0519	Catalyzes the synthesis of GMP from XMP
B7C62_RS16050	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS16065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS16080	COG1695	Transcriptional regulator
B7C62_RS16090	COG0667	Aldo Keto reductase
B7C62_RS16100	COG1609	Transcriptional regulator
B7C62_RS16105	COG2124	cytochrome p450
B7C62_RS16110	COG2124	cytochrome p450
B7C62_RS16135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7C62_RS16150	COG3585	molybdate ion transport
B7C62_RS16195	COG2409	Drug exporters of the RND superfamily
B7C62_RS16200	COG3594	Acyltransferase
B7C62_RS16205	COG0513	Belongs to the DEAD box helicase family
B7C62_RS16210	COG1278	Cold shock
B7C62_RS16250	COG0454	-acetyltransferase
B7C62_RS16265	COG1136	(ABC) transporter
B7C62_RS16265	COG0577	efflux transmembrane transporter activity
B7C62_RS16270	COG1136	(ABC) transporter
B7C62_RS16290	COG1585	Membrane protein implicated in regulation of membrane protease activity
B7C62_RS16295	COG2268	Band 7 protein
B7C62_RS16345	COG2255	four-way junction helicase activity
B7C62_RS16355	COG0180	Tryptophanyl-tRNA synthetase
B7C62_RS16360	COG2015	COG2015, Alkyl sulfatase and related hydrolases
B7C62_RS16365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS16395	COG0431	NADPH-dependent FMN reductase
B7C62_RS16420	COG2304	oxidoreductase activity
B7C62_RS16425	COG2205	protein histidine kinase activity
B7C62_RS16430	COG0745	RESPONSE REGULATOR receiver
B7C62_RS16435	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7C62_RS16450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B7C62_RS16455	COG2208	phosphoserine phosphatase activity
B7C62_RS16455	COG2172	sigma factor antagonist activity
B7C62_RS16455	COG1366	Belongs to the anti-sigma-factor antagonist family
B7C62_RS16465	COG1741	Belongs to the pirin family
B7C62_RS16475	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS16485	COG1362	aminopeptidase activity
B7C62_RS16520	COG2271	Major facilitator Superfamily
B7C62_RS16570	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7C62_RS16575	COG0022	dehydrogenase e1 component
B7C62_RS16600	COG0515	serine threonine protein kinase
B7C62_RS16605	COG0515	serine threonine protein kinase
B7C62_RS16620	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7C62_RS16620	COG1136	(ABC) transporter
B7C62_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS16635	COG3321	synthase
B7C62_RS16635	COG0604	alcohol dehydrogenase
B7C62_RS16650	COG0746	molybdenum cofactor guanylyltransferase activity
B7C62_RS16670	COG1522	sequence-specific DNA binding
B7C62_RS16675	COG1309	transcriptional regulator
B7C62_RS16700	COG3396	Phenylacetate-CoA oxygenase
B7C62_RS16705	COG3460	Phenylacetate-CoA oxygenase
B7C62_RS16710	COG3396	Phenylacetate-CoA oxygenase
B7C62_RS16715	COG2151	metal-sulfur cluster biosynthetic enzyme
B7C62_RS16720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7C62_RS16730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7C62_RS16760	COG1716	ATPase activity
B7C62_RS16765	COG1716	ATPase activity
B7C62_RS16780	COG0768	penicillin binding
B7C62_RS16785	COG0515	serine threonine protein kinase
B7C62_RS16790	COG3764	Sortase (surface protein transpeptidase)
B7C62_RS16795	COG3764	Sortase (surface protein transpeptidase)
B7C62_RS16810	COG3764	Sortase (surface protein transpeptidase)
B7C62_RS16825	COG0705	Rhomboid family
B7C62_RS16850	COG1104	cysteine desulfurase activity
B7C62_RS16930	COG0741	lytic transglycosylase activity
B7C62_RS16930	COG0739	heme binding
B7C62_RS16930	COG1196	nuclear chromosome segregation
B7C62_RS17020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7C62_RS17145	COG0587	DNA-directed DNA polymerase activity
B7C62_RS17160	COG0582	viral genome integration into host DNA
B7C62_RS17175	COG0515	serine threonine protein kinase
B7C62_RS17230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7C62_RS17240	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
B7C62_RS17245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B7C62_RS17250	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B7C62_RS17255	COG0592	DNA-directed DNA polymerase activity
B7C62_RS17270	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B7C62_RS17275	COG0594	ribonuclease P activity
B7C62_RS17280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B7C62_RS17285	COG0706	membrane insertase activity
B7C62_RS17295	COG0357	Ribosomal RNA small subunit methyltransferase G
B7C62_RS17300	COG1192	Involved in chromosome partitioning
B7C62_RS17315	COG3118	belongs to the thioredoxin family
B7C62_RS17320	COG0492	ferredoxin-NADP+ reductase activity
B7C62_RS17330	COG1595	DNA-templated transcription, initiation
B7C62_RS17335	COG0515	serine threonine protein kinase
B7C62_RS17335	COG2815	serine threonine protein kinase
B7C62_RS17350	COG0617	tRNA 3'-terminal CCA addition
B7C62_RS17370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7C62_RS17395	COG0360	Binds together with S18 to 16S ribosomal RNA
B7C62_RS17400	COG0629	single-stranded DNA binding
B7C62_RS17405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B7C62_RS17410	COG0359	binds to the 23S rRNA
B7C62_RS17415	COG0534	Mate efflux family protein
B7C62_RS17420	COG0305	Participates in initiation and elongation during chromosome replication
B7C62_RS17425	COG0242	peptide deformylase activity
B7C62_RS17435	COG0137	argininosuccinate synthase activity
B7C62_RS17455	COG2814	Major facilitator Superfamily
B7C62_RS17475	COG0626	cystathionine gamma-synthase activity
B7C62_RS17480	COG1950	PFAM Membrane protein of
B7C62_RS17485	COG0662	Cupin 2, conserved barrel domain protein
B7C62_RS17510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B7C62_RS17525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7C62_RS17530	COG1609	Transcriptional regulator
B7C62_RS17535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7C62_RS17540	COG1271	oxidase subunit
B7C62_RS17545	COG1294	oxidase, subunit
B7C62_RS17550	COG4988	ABC transporter
B7C62_RS17560	COG0561	phosphatase activity
B7C62_RS17575	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B7C62_RS17580	COG0789	Transcriptional regulator
B7C62_RS17595	COG1131	(ABC) transporter
B7C62_RS17620	COG0561	phosphatase activity
B7C62_RS17625	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B7C62_RS17635	COG2837	iron assimilation
B7C62_RS17640	COG2372	response to copper ion
B7C62_RS17650	COG1999	signal sequence binding
B7C62_RS17670	COG0006	proline dipeptidase activity
B7C62_RS17690	COG0653	protein targeting
B7C62_RS17745	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS17770	COG1595	DNA-templated transcription, initiation
B7C62_RS17775	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS17860	COG0745	RESPONSE REGULATOR receiver
B7C62_RS17865	COG2205	protein histidine kinase activity
B7C62_RS17875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B7C62_RS17885	COG0477	Major facilitator Superfamily
B7C62_RS17900	COG3467	pyridoxamine 5'-phosphate
B7C62_RS17905	COG2353	YceI-like domain
B7C62_RS17930	COG1191	sigma factor activity
B7C62_RS17935	COG1191	sigma factor activity
B7C62_RS17950	COG1518	maintenance of DNA repeat elements
B7C62_RS18025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B7C62_RS18110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7C62_RS18255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7C62_RS18275	COG1215	transferase activity, transferring glycosyl groups
B7C62_RS18280	COG0525	valine-tRNA ligase activity
B7C62_RS18310	COG0151	Belongs to the GarS family
B7C62_RS18340	COG1136	(ABC) transporter
B7C62_RS18345	COG0577	efflux transmembrane transporter activity
B7C62_RS18345	COG1136	(ABC) transporter
B7C62_RS18350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B7C62_RS18360	COG2197	response regulator
B7C62_RS18375	COG1131	(ABC) transporter
B7C62_RS18395	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7C62_RS18400	COG0047	phosphoribosylformylglycinamidine synthase activity
B7C62_RS18405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7C62_RS18415	COG1196	nuclear chromosome segregation
B7C62_RS18415	COG0741	lytic transglycosylase activity
B7C62_RS18415	COG0739	heme binding
B7C62_RS18435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B7C62_RS18470	COG1643	Atp-dependent helicase
B7C62_RS18480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7C62_RS18480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7C62_RS18485	COG0785	Cytochrome C biogenesis protein
B7C62_RS18515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B7C62_RS18520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B7C62_RS18530	COG0513	Belongs to the DEAD box helicase family
B7C62_RS18545	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS18560	COG4221	oxidoreductase activity
B7C62_RS18570	COG0789	Transcriptional regulator
B7C62_RS18580	COG0741	lytic transglycosylase activity
B7C62_RS18580	COG0739	heme binding
B7C62_RS18580	COG1196	nuclear chromosome segregation
B7C62_RS18585	COG0667	Aldo Keto reductase
B7C62_RS18610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B7C62_RS18615	COG0579	oxidoreductase
B7C62_RS18640	COG1252	NADH dehydrogenase
B7C62_RS18655	COG1846	Transcriptional regulator
B7C62_RS18715	COG0739	heme binding
B7C62_RS18715	COG0741	lytic transglycosylase activity
B7C62_RS18715	COG1196	nuclear chromosome segregation
B7C62_RS18720	COG0671	phosphoesterase, PA-phosphatase related
B7C62_RS18740	COG1937	Protein conserved in bacteria
B7C62_RS18750	COG0306	phosphate transporter
B7C62_RS18770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7C62_RS18780	COG0494	nUDIX hydrolase
B7C62_RS18780	COG0406	alpha-ribazole phosphatase activity
B7C62_RS18800	COG3842	ATPase activity
B7C62_RS18805	COG1725	Transcriptional regulator
B7C62_RS18815	COG0456	acetyltransferase
B7C62_RS18825	COG0737	Belongs to the 5'-nucleotidase family
B7C62_RS18830	COG2936	dipeptidyl-peptidase activity
B7C62_RS18860	COG2755	lipolytic protein G-D-S-L family
B7C62_RS18885	COG0367	asparagine synthase
B7C62_RS18890	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B7C62_RS18895	COG0010	Belongs to the arginase family
B7C62_RS18900	COG2175	clavaminate synthase activity
B7C62_RS18905	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7C62_RS18955	COG3634	alkyl hydroperoxide reductase activity
B7C62_RS18970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7C62_RS18975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7C62_RS19025	COG0823	Involved in the tonB-independent uptake of proteins
B7C62_RS19030	COG0515	serine threonine protein kinase
B7C62_RS19030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7C62_RS19035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7C62_RS19035	COG0515	serine threonine protein kinase
B7C62_RS19050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7C62_RS19055	COG1609	Transcriptional regulator
B7C62_RS19060	COG0745	RESPONSE REGULATOR receiver
B7C62_RS19090	COG2897	thiosulfate sulfurtransferase activity
B7C62_RS19125	COG3485	protocatechuate 3,4-dioxygenase
B7C62_RS19130	COG0735	belongs to the Fur family
B7C62_RS19140	COG1490	D-aminoacyl-tRNA deacylase activity
B7C62_RS19155	COG4552	Acetyltransferase involved in intracellular survival and related
B7C62_RS19185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7C62_RS19185	COG0515	serine threonine protein kinase
B7C62_RS19225	COG2318	DinB family
B7C62_RS19235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS19245	COG1733	regulation of RNA biosynthetic process
B7C62_RS19265	COG0539	negative regulation of cytoplasmic translation
B7C62_RS19270	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B7C62_RS19305	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS19350	COG0588	phosphoglycerate mutase activity
B7C62_RS19365	COG5002	protein histidine kinase activity
B7C62_RS19385	COG1329	Transcriptional regulator
B7C62_RS19390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B7C62_RS19395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B7C62_RS19400	COG3467	pyridoxamine 5'-phosphate
B7C62_RS19405	COG0215	cysteine-tRNA ligase activity
B7C62_RS19410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7C62_RS19430	COG3842	ATPase activity
B7C62_RS19455	COG0745	RESPONSE REGULATOR receiver
B7C62_RS19495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7C62_RS19540	COG2197	response regulator
B7C62_RS19545	COG4585	Histidine kinase
B7C62_RS19555	COG0666	response to abiotic stimulus
B7C62_RS19580	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B7C62_RS19600	COG1105	Belongs to the carbohydrate kinase PfkB family
B7C62_RS19605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7C62_RS19635	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B7C62_RS19640	COG0463	Glycosyl transferase, family 2
B7C62_RS19690	COG1132	(ABC) transporter
B7C62_RS19735	COG4249	Peptidase C14 caspase catalytic subunit p20
B7C62_RS19735	COG2319	Wd-40 repeat
B7C62_RS19750	COG1595	DNA-templated transcription, initiation
B7C62_RS19790	COG0395	ABC-type sugar transport system, permease component
B7C62_RS19795	COG1175	transmembrane transport
B7C62_RS19835	COG4251	negative regulation of phosphorylation
B7C62_RS19835	COG4251	negative regulation of phosphorylation
B7C62_RS19840	COG2197	response regulator
B7C62_RS19860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B7C62_RS19865	COG1737	Transcriptional regulator
B7C62_RS19895	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B7C62_RS19900	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B7C62_RS19905	COG1984	allophanate hydrolase subunit 2
B7C62_RS19915	COG3142	Participates in the control of copper homeostasis
B7C62_RS19920	COG3973	AAA domain
B7C62_RS19940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7C62_RS19945	COG1120	ATPase activity
B7C62_RS19955	COG1061	Type III restriction enzyme res subunit
B7C62_RS19960	COG1846	Transcriptional regulator
B7C62_RS19985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7C62_RS19990	COG1120	ATPase activity
B7C62_RS19995	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS20000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS20020	COG1278	Cold shock
B7C62_RS20035	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B7C62_RS20040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7C62_RS20050	COG2814	Major facilitator Superfamily
B7C62_RS20080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7C62_RS20090	COG2252	PERMEase
B7C62_RS20115	COG0697	spore germination
B7C62_RS20125	COG0667	Aldo Keto reductase
B7C62_RS20140	COG0515	serine threonine protein kinase
B7C62_RS20145	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS20150	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS20155	COG0583	DNA-binding transcription factor activity
B7C62_RS20180	COG1595	DNA-templated transcription, initiation
B7C62_RS20250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B7C62_RS20255	COG0406	alpha-ribazole phosphatase activity
B7C62_RS20330	COG3250	beta-galactosidase activity
B7C62_RS20330	COG5297	Belongs to the glycosyl hydrolase family 6
B7C62_RS20340	COG1309	transcriptional regulator
B7C62_RS20345	COG1472	Belongs to the glycosyl hydrolase 3 family
B7C62_RS20350	COG0697	spore germination
B7C62_RS20355	COG1846	Transcriptional regulator
B7C62_RS20410	COG1335	isochorismatase
B7C62_RS20455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B7C62_RS20485	COG2205	protein histidine kinase activity
B7C62_RS20490	COG0277	FAD linked oxidase domain protein
B7C62_RS20490	COG0247	lactate metabolic process
B7C62_RS20510	COG5006	permease, DMT superfamily
B7C62_RS20515	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
B7C62_RS20525	COG1051	belongs to the nudix hydrolase family
B7C62_RS20535	COG2197	response regulator
B7C62_RS20570	COG2226	methyltransferase
B7C62_RS20575	COG1132	(ABC) transporter
B7C62_RS20595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7C62_RS20610	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS20615	COG1024	Enoyl-CoA hydratase
B7C62_RS20765	COG0259	pyridoxamine-phosphate oxidase activity
B7C62_RS20795	COG4821	SIS domain
B7C62_RS20805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7C62_RS20820	COG1131	(ABC) transporter
B7C62_RS20905	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS20915	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS20920	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS20935	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS20940	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS20965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7C62_RS21025	COG1024	Enoyl-CoA hydratase
B7C62_RS21070	COG2072	flavoprotein involved in K transport
B7C62_RS21075	COG4592	Periplasmic binding protein
B7C62_RS21080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS21085	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS21120	COG0501	Belongs to the peptidase M48B family
B7C62_RS21125	COG0259	pyridoxamine-phosphate oxidase activity
B7C62_RS21135	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS21145	COG1309	transcriptional regulator
B7C62_RS21170	COG1024	Enoyl-CoA hydratase
B7C62_RS21185	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS21215	COG1278	Cold shock
B7C62_RS21220	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B7C62_RS21230	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B7C62_RS21255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7C62_RS21260	COG4521	taurine ABC transporter
B7C62_RS21270	COG2175	clavaminate synthase activity
B7C62_RS21275	COG2226	methyltransferase
B7C62_RS21310	COG0789	Transcriptional regulator
B7C62_RS21345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7C62_RS21350	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7C62_RS21355	COG0649	NAD binding
B7C62_RS21365	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7C62_RS21370	COG1034	ATP synthesis coupled electron transport
B7C62_RS21375	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B7C62_RS21380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7C62_RS21385	COG0839	Belongs to the complex I subunit 6 family
B7C62_RS21390	COG0713	ATP synthesis coupled electron transport
B7C62_RS21395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7C62_RS21405	COG1007	ATP synthesis coupled electron transport
B7C62_RS21410	COG0514	ATP-dependent DNA helicase (RecQ)
B7C62_RS21420	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7C62_RS21430	COG3104	oligopeptide transport
B7C62_RS21435	COG0142	geranyltranstransferase activity
B7C62_RS21455	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B7C62_RS21465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7C62_RS21485	COG0561	phosphatase activity
B7C62_RS21595	COG3226	Transcriptional regulator
B7C62_RS21640	COG0702	epimerase
B7C62_RS21645	COG1733	regulation of RNA biosynthetic process
B7C62_RS21650	COG1013	pyruvate-flavodoxin oxidoreductase activity
B7C62_RS21655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B7C62_RS21655	COG0674	pyruvate-flavodoxin oxidoreductase activity
B7C62_RS21680	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7C62_RS21685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7C62_RS21690	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7C62_RS21695	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B7C62_RS21700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7C62_RS21705	COG0839	Belongs to the complex I subunit 6 family
B7C62_RS21710	COG0713	ATP synthesis coupled electron transport
B7C62_RS21715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7C62_RS21720	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7C62_RS21725	COG1007	ATP synthesis coupled electron transport
B7C62_RS21730	COG1970	mechanosensitive ion channel activity
B7C62_RS21735	COG0501	Belongs to the peptidase M48B family
B7C62_RS21740	COG3304	Inner membrane component domain
B7C62_RS21755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7C62_RS21760	COG1666	GTP binding
B7C62_RS21790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B7C62_RS21795	COG2030	dehydratase
B7C62_RS21805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B7C62_RS21810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7C62_RS21815	COG0436	Aminotransferase
B7C62_RS21835	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B7C62_RS21840	COG0081	regulation of translation
B7C62_RS21850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B7C62_RS21855	COG0222	ribosome binding
B7C62_RS21865	COG0085	RNA polymerase activity
B7C62_RS21870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B7C62_RS21985	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B7C62_RS21990	COG0049	tRNA binding
B7C62_RS21995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B7C62_RS22000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7C62_RS22005	COG4585	Histidine kinase
B7C62_RS22010	COG3209	COG3209 Rhs family protein
B7C62_RS22020	COG2197	response regulator
B7C62_RS22035	COG0051	transcription antitermination factor activity, RNA binding
B7C62_RS22040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B7C62_RS22045	COG0088	Forms part of the polypeptide exit tunnel
B7C62_RS22050	COG0089	rRNA binding
B7C62_RS22055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B7C62_RS22060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B7C62_RS22065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B7C62_RS22070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B7C62_RS22075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B7C62_RS22080	COG0255	Belongs to the universal ribosomal protein uL29 family
B7C62_RS22085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B7C62_RS22090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B7C62_RS22095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B7C62_RS22100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B7C62_RS22105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B7C62_RS22115	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B7C62_RS22120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B7C62_RS22125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B7C62_RS22130	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B7C62_RS22135	COG1841	ribosomal large subunit assembly
B7C62_RS22140	COG0200	Binds to the 23S rRNA
B7C62_RS22150	COG0563	adenylate kinase activity
B7C62_RS22160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B7C62_RS22165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B7C62_RS22170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B7C62_RS22175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B7C62_RS22180	COG0202	RNA polymerase activity
B7C62_RS22185	COG0203	ribosomal protein L17
B7C62_RS22190	COG0101	tRNA pseudouridine synthase activity
B7C62_RS22205	COG0488	(ABC) transporter
B7C62_RS22210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B7C62_RS22215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B7C62_RS22220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7C62_RS22240	COG1072	(Pantothenic acid kinase))
B7C62_RS22255	COG1595	DNA-templated transcription, initiation
B7C62_RS22280	COG1404	Belongs to the peptidase S8 family
B7C62_RS22295	COG4566	intracellular signal transduction
B7C62_RS22315	COG4941	Belongs to the sigma-70 factor family
B7C62_RS22360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7C62_RS22365	COG0736	holo-[acyl-carrier-protein] synthase activity
B7C62_RS22375	COG3189	MarR family transcriptional regulator
B7C62_RS22380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7C62_RS22390	COG0802	atpase or kinase
B7C62_RS22415	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B7C62_RS22450	COG0726	polysaccharide deacetylase
B7C62_RS22455	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B7C62_RS22465	COG4221	oxidoreductase activity
B7C62_RS22475	COG0583	DNA-binding transcription factor activity
B7C62_RS22485	COG2197	response regulator
B7C62_RS22490	COG1595	DNA-templated transcription, initiation
B7C62_RS22500	COG0516	GMP reductase activity
B7C62_RS22515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7C62_RS22530	COG2815	serine threonine protein kinase
B7C62_RS22530	COG0515	serine threonine protein kinase
B7C62_RS22540	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS22560	COG0519	Catalyzes the synthesis of GMP from XMP
B7C62_RS22560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7C62_RS22600	COG2197	response regulator
B7C62_RS22605	COG0791	NLP P60 protein
B7C62_RS22635	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7C62_RS22650	COG0714	Associated with various cellular activities
B7C62_RS22655	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B7C62_RS22660	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B7C62_RS22665	COG0045	succinate-CoA ligase (ADP-forming) activity
B7C62_RS22695	COG0138	bifunctional purine biosynthesis protein purh
B7C62_RS22710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B7C62_RS22725	COG0039	L-malate dehydrogenase activity
B7C62_RS22735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7C62_RS22755	COG2816	NAD+ diphosphatase activity
B7C62_RS22785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7C62_RS22800	COG0754	glutathionylspermidine amidase activity
B7C62_RS22805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7C62_RS22810	COG0180	Tryptophanyl-tRNA synthetase
B7C62_RS22830	COG1295	ribonuclease BN
B7C62_RS22835	COG1686	Belongs to the peptidase S11 family
B7C62_RS22845	COG1408	metallophosphoesterase
B7C62_RS22850	COG0747	negative chemotaxis
B7C62_RS22875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7C62_RS22880	COG1053	succinate dehydrogenase
B7C62_RS22890	COG2009	succinate dehydrogenase
B7C62_RS22935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B7C62_RS22940	COG1595	DNA-templated transcription, initiation
B7C62_RS22970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B7C62_RS22990	COG1216	Glycosyl transferase, family 2
B7C62_RS23000	COG1083	cytidylyl-transferase
B7C62_RS23005	COG2089	acid synthase
B7C62_RS23015	COG1473	amidohydrolase
B7C62_RS23015	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B7C62_RS23020	COG1744	ABC transporter substrate-binding protein PnrA-like
B7C62_RS23025	COG3845	ABC transporter
B7C62_RS23030	COG4603	Belongs to the binding-protein-dependent transport system permease family
B7C62_RS23035	COG1079	Belongs to the binding-protein-dependent transport system permease family
B7C62_RS23055	COG1404	Belongs to the peptidase S8 family
B7C62_RS23075	COG2814	Major facilitator Superfamily
B7C62_RS23080	COG0583	DNA-binding transcription factor activity
B7C62_RS23100	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7C62_RS23125	COG2205	protein histidine kinase activity
B7C62_RS23130	COG0745	RESPONSE REGULATOR receiver
B7C62_RS23135	COG1595	DNA-templated transcription, initiation
B7C62_RS23150	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS23155	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS23185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7C62_RS23215	COG4770	biotin carboxylase activity
B7C62_RS23225	COG0424	maF-like protein
B7C62_RS23235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7C62_RS23250	COG1024	Enoyl-CoA hydratase
B7C62_RS23280	COG1376	ErfK ybiS ycfS ynhG family protein
B7C62_RS23360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7C62_RS23365	COG1396	sequence-specific DNA binding
B7C62_RS23440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7C62_RS23450	COG0501	Belongs to the peptidase M48B family
B7C62_RS23470	COG1595	DNA-templated transcription, initiation
B7C62_RS23475	COG2255	four-way junction helicase activity
B7C62_RS23480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7C62_RS23495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7C62_RS23505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7C62_RS23555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7C62_RS23555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7C62_RS23575	COG1331	Highly conserved protein containing a thioredoxin domain
B7C62_RS23595	COG1331	Highly conserved protein containing a thioredoxin domain
B7C62_RS23605	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
B7C62_RS23670	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B7C62_RS23685	COG1414	Transcriptional regulator
B7C62_RS23690	COG0251	oxidation-reduction process
B7C62_RS23695	COG2610	gluconate transmembrane transporter activity
B7C62_RS23730	COG2894	cell division
B7C62_RS23765	COG2197	response regulator
B7C62_RS23785	COG2885	chlorophyll binding
B7C62_RS23815	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B7C62_RS23835	COG0667	Aldo Keto reductase
B7C62_RS23840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7C62_RS23850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B7C62_RS23865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7C62_RS23870	COG0450	alkyl hydroperoxide reductase
B7C62_RS23885	COG1136	(ABC) transporter
B7C62_RS23920	COG0114	fumarate hydratase activity
B7C62_RS23930	COG1362	aminopeptidase activity
B7C62_RS23935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7C62_RS23935	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7C62_RS23960	COG0778	Nitroreductase
B7C62_RS23965	COG1722	exodeoxyribonuclease VII activity
B7C62_RS23970	COG1570	exodeoxyribonuclease VII activity
B7C62_RS23975	COG0531	amino acid
B7C62_RS23980	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B7C62_RS23995	COG0012	GTP binding
B7C62_RS24030	COG2423	ornithine cyclodeaminase activity
B7C62_RS24035	COG2409	Drug exporters of the RND superfamily
B7C62_RS24050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7C62_RS24065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS24075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7C62_RS24080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7C62_RS24095	COG2091	lysine biosynthetic process via aminoadipic acid
B7C62_RS24155	COG0789	Transcriptional regulator
B7C62_RS24200	COG1842	Phage shock protein A
B7C62_RS24210	COG0463	Glycosyl transferase, family 2
B7C62_RS24220	COG4941	Belongs to the sigma-70 factor family
B7C62_RS24225	COG3795	YCII-related domain
B7C62_RS24265	COG3415	Transposase
B7C62_RS24265	COG2801	Transposase and inactivated derivatives
B7C62_RS24280	COG2318	DinB family
B7C62_RS24290	COG3415	Transposase
B7C62_RS24290	COG2801	Transposase and inactivated derivatives
B7C62_RS24295	COG0300	oxidoreductase activity
B7C62_RS24315	COG2226	methyltransferase
B7C62_RS24325	COG1217	gtp-binding protein TYPA
B7C62_RS24330	COG4166	transmembrane transport
B7C62_RS24335	COG0601	transmembrane transport
B7C62_RS24340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7C62_RS24345	COG0444	Belongs to the ABC transporter superfamily
B7C62_RS24350	COG4608	Belongs to the ABC transporter superfamily
B7C62_RS24355	COG4166	transmembrane transport
B7C62_RS24365	COG0601	transmembrane transport
B7C62_RS24370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7C62_RS24380	COG4608	Belongs to the ABC transporter superfamily
B7C62_RS24395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7C62_RS24410	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
B7C62_RS24415	COG1396	sequence-specific DNA binding
B7C62_RS24420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7C62_RS24430	COG0110	maltose O-acetyltransferase activity
B7C62_RS24445	COG0515	serine threonine protein kinase
B7C62_RS24455	COG1132	(ABC) transporter
B7C62_RS24460	COG1132	(ABC) transporter
B7C62_RS24465	COG2197	response regulator
B7C62_RS24470	COG2912	Transglutaminase-like superfamily
B7C62_RS24500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7C62_RS24505	COG1611	Belongs to the LOG family
B7C62_RS24510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7C62_RS24520	COG0519	Catalyzes the synthesis of GMP from XMP
B7C62_RS24525	COG1024	Enoyl-CoA hydratase
B7C62_RS24540	COG1595	DNA-templated transcription, initiation
B7C62_RS24550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7C62_RS24555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7C62_RS24590	COG0598	Magnesium transport protein CorA
B7C62_RS24605	COG0613	PHP domain protein
B7C62_RS24610	COG2095	MarC family integral membrane protein
B7C62_RS24615	COG1432	Conserved Protein
B7C62_RS24625	COG0513	Belongs to the DEAD box helicase family
B7C62_RS24665	COG0747	negative chemotaxis
B7C62_RS24675	COG0601	transmembrane transport
B7C62_RS24735	COG0210	DNA helicase
B7C62_RS24780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B7C62_RS24830	COG3480	Lon protease (S16) C-terminal proteolytic domain
B7C62_RS24840	COG1615	UPF0182 protein
B7C62_RS24865	COG0753	catalase activity
B7C62_RS24875	COG0483	inositol monophosphate 1-phosphatase activity
B7C62_RS24885	COG2076	Multidrug Resistance protein
B7C62_RS24890	COG1162	GTPase activity
B7C62_RS24895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B7C62_RS24905	COG2135	peptidase activity
B7C62_RS24915	COG1595	DNA-templated transcription, initiation
B7C62_RS24920	COG5662	AntiSigma factor
B7C62_RS24925	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B7C62_RS24925	COG2199	diguanylate cyclase activity
B7C62_RS24940	COG0242	peptide deformylase activity
B7C62_RS25050	COG1131	(ABC) transporter
B7C62_RS25080	COG1569	PIN domain
B7C62_RS25085	COG3311	Transcriptional regulator
B7C62_RS25100	COG0640	Transcriptional regulator
B7C62_RS25105	COG0798	PFAM Bile acid sodium symporter
B7C62_RS25110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7C62_RS25135	COG1966	Carbon starvation protein
B7C62_RS25150	COG1442	glycosyl transferase family 8
B7C62_RS25150	COG1216	Glycosyl transferase, family 2
B7C62_RS25160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7C62_RS25165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7C62_RS25175	COG1215	transferase activity, transferring glycosyl groups
B7C62_RS25195	COG0667	Aldo Keto reductase
B7C62_RS25205	COG2182	Extracellular solute-binding protein
B7C62_RS25210	COG1175	transmembrane transport
B7C62_RS25215	COG0395	ABC-type sugar transport system, permease component
B7C62_RS25220	COG1472	Belongs to the glycosyl hydrolase 3 family
B7C62_RS25225	COG0363	glucosamine-6-phosphate deaminase activity
B7C62_RS25230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7C62_RS25245	COG1597	lipid kinase activity
B7C62_RS25260	COG2172	sigma factor antagonist activity
B7C62_RS25285	COG1959	2 iron, 2 sulfur cluster binding
B7C62_RS25290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7C62_RS25295	COG0142	geranyltranstransferase activity
B7C62_RS25355	COG4106	trans-aconitate 2-methyltransferase activity
B7C62_RS25360	COG1126	abc transporter atp-binding protein
B7C62_RS25365	COG0765	amino acid transport
B7C62_RS25370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7C62_RS25375	COG0281	malic enzyme
B7C62_RS25380	COG0604	alcohol dehydrogenase
B7C62_RS25385	COG1874	Beta-galactosidase
B7C62_RS25425	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7C62_RS25425	COG0567	Dehydrogenase, E1 component
B7C62_RS25435	COG2205	protein histidine kinase activity
B7C62_RS25440	COG0745	RESPONSE REGULATOR receiver
B7C62_RS25460	COG1131	(ABC) transporter
B7C62_RS25470	COG1595	DNA-templated transcription, initiation
B7C62_RS25480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7C62_RS25485	COG0726	polysaccharide deacetylase
B7C62_RS25490	COG1846	Transcriptional regulator
B7C62_RS25500	COG5002	protein histidine kinase activity
B7C62_RS25525	COG0791	NLP P60 protein
B7C62_RS25540	COG1309	transcriptional regulator
B7C62_RS25555	COG2267	carboxylic ester hydrolase activity
B7C62_RS25625	COG0768	penicillin binding
B7C62_RS25640	COG2205	protein histidine kinase activity
B7C62_RS25660	COG3285	dna ligase
B7C62_RS25660	COG1793	dna ligase
B7C62_RS25665	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B7C62_RS25700	COG0018	arginyl-trna synthetase
B7C62_RS25705	COG0019	diaminopimelate decarboxylase activity
B7C62_RS25710	COG0460	homoserine dehydrogenase
B7C62_RS25715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7C62_RS25720	COG0083	homoserine kinase activity
B7C62_RS25730	COG1316	TRANSCRIPTIONal
B7C62_RS25735	COG0254	rRNA binding
B7C62_RS25740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B7C62_RS25745	COG2890	protein-(glutamine-N5) methyltransferase activity
B7C62_RS25755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7C62_RS25760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B7C62_RS25780	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B7C62_RS25785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B7C62_RS25790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B7C62_RS25795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B7C62_RS25800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B7C62_RS25805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B7C62_RS25810	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B7C62_RS25825	COG2197	response regulator
B7C62_RS25845	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7C62_RS25860	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
B7C62_RS25915	COG0183	Belongs to the thiolase family
B7C62_RS25930	COG0745	RESPONSE REGULATOR receiver
B7C62_RS25935	COG5002	protein histidine kinase activity
B7C62_RS26010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7C62_RS26010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7C62_RS26015	COG1597	lipid kinase activity
B7C62_RS26065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7C62_RS26070	COG0280	phosphate acetyltransferase
B7C62_RS26070	COG0857	belongs to the CobB CobQ family
B7C62_RS26075	COG0205	6-phosphofructokinase activity
B7C62_RS26085	COG4565	transcriptional regulatory protein
B7C62_RS26090	COG3290	protein histidine kinase activity
B7C62_RS26095	COG1301	dicarboxylic acid transport
B7C62_RS26105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B7C62_RS26110	COG3281	Trehalose synthase
B7C62_RS26115	COG0366	Alpha amylase catalytic
B7C62_RS26120	COG0366	Alpha amylase catalytic
B7C62_RS26125	COG0058	SHG alpha-glucan phosphorylase activity
B7C62_RS26155	COG0477	Major facilitator Superfamily
B7C62_RS26170	COG1132	(ABC) transporter
B7C62_RS26175	COG1132	(ABC) transporter
B7C62_RS26180	COG1131	(ABC) transporter
B7C62_RS26195	COG2197	response regulator
B7C62_RS26225	COG0726	polysaccharide deacetylase
B7C62_RS26345	COG2235	arginine
B7C62_RS26380	COG4585	Histidine kinase
B7C62_RS26385	COG2197	response regulator
B7C62_RS26395	COG0577	efflux transmembrane transporter activity
B7C62_RS26395	COG1136	(ABC) transporter
B7C62_RS26400	COG1902	pentaerythritol trinitrate reductase activity
B7C62_RS26420	COG1760	l-serine dehydratase
B7C62_RS26425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B7C62_RS26430	COG0509	glycine decarboxylation via glycine cleavage system
B7C62_RS26435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B7C62_RS26455	COG4166	transmembrane transport
B7C62_RS26460	COG0601	transmembrane transport
B7C62_RS26465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7C62_RS26470	COG0444	Belongs to the ABC transporter superfamily
B7C62_RS26475	COG4608	Belongs to the ABC transporter superfamily
B7C62_RS26480	COG2860	membrane
B7C62_RS26510	COG0482	sulfurtransferase activity
B7C62_RS26530	COG4221	oxidoreductase activity
B7C62_RS26540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7C62_RS26550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7C62_RS26555	COG0154	amidase activity
B7C62_RS26565	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7C62_RS26570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7C62_RS26580	COG2409	Drug exporters of the RND superfamily
B7C62_RS26600	COG2197	response regulator
B7C62_RS26620	COG2133	pyrroloquinoline quinone binding
B7C62_RS26625	COG0667	Aldo Keto reductase
B7C62_RS26645	COG0440	acetolactate synthase activity
B7C62_RS26650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B7C62_RS26675	COG1131	(ABC) transporter
B7C62_RS26710	COG2197	response regulator
B7C62_RS26715	COG3851	Histidine kinase
B7C62_RS26725	COG1131	(ABC) transporter
B7C62_RS26780	COG2197	response regulator
B7C62_RS26795	COG0506	proline dehydrogenase activity
B7C62_RS26800	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS26805	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B7C62_RS26805	COG0778	Nitroreductase
B7C62_RS26820	COG2130	NADP-dependent
B7C62_RS26825	COG0583	DNA-binding transcription factor activity
B7C62_RS26830	COG0473	3-isopropylmalate dehydrogenase activity
B7C62_RS26835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7C62_RS26840	COG2957	Belongs to the agmatine deiminase family
B7C62_RS26855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7C62_RS26875	COG0601	transmembrane transport
B7C62_RS26880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7C62_RS26885	COG0444	Belongs to the ABC transporter superfamily
B7C62_RS26895	COG1472	Belongs to the glycosyl hydrolase 3 family
B7C62_RS26915	COG1309	transcriptional regulator
B7C62_RS26925	COG3708	Transcriptional regulator
B7C62_RS26925	COG2207	Transcriptional regulator
B7C62_RS26970	COG0492	ferredoxin-NADP+ reductase activity
B7C62_RS27015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS27020	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS27025	COG1120	ATPase activity
B7C62_RS27030	COG4607	ABC-type enterochelin transport system periplasmic component
B7C62_RS27050	COG0366	Alpha amylase catalytic
B7C62_RS27050	COG1470	cell adhesion involved in biofilm formation
B7C62_RS27055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7C62_RS27075	COG2018	Roadblock/LC7 domain
B7C62_RS27095	COG2018	Roadblock/LC7 domain
B7C62_RS27100	COG5002	protein histidine kinase activity
B7C62_RS27110	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7C62_RS27115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7C62_RS27160	COG1414	Transcriptional regulator
B7C62_RS27165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B7C62_RS27170	COG0066	3-isopropylmalate dehydratase activity
B7C62_RS27180	COG0776	regulation of translation
B7C62_RS27190	COG1920	GTP binding
B7C62_RS27200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B7C62_RS27205	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7C62_RS27220	COG0351	phosphomethylpyrimidine kinase
B7C62_RS27225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B7C62_RS27230	COG1461	Dihydroxyacetone kinase
B7C62_RS27235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7C62_RS27240	COG0742	ribosomal rna small subunit methyltransferase
B7C62_RS27245	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B7C62_RS27260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B7C62_RS27265	COG0571	ribonuclease III activity
B7C62_RS27270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B7C62_RS27275	COG1733	regulation of RNA biosynthetic process
B7C62_RS27280	COG2340	Cysteine-rich secretory protein family
B7C62_RS27285	COG1254	Belongs to the acylphosphatase family
B7C62_RS27300	COG1196	nuclear chromosome segregation
B7C62_RS27305	COG0477	Major facilitator Superfamily
B7C62_RS27340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B7C62_RS27360	COG0228	four-way junction DNA binding
B7C62_RS27365	COG1837	Belongs to the UPF0109 family
B7C62_RS27370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7C62_RS27375	COG0336	Belongs to the RNA methyltransferase TrmD family
B7C62_RS27380	COG0335	large ribosomal subunit rRNA binding
B7C62_RS27390	COG0681	Belongs to the peptidase S26 family
B7C62_RS27415	COG0792	nuclease activity
B7C62_RS27430	COG1191	sigma factor activity
B7C62_RS27445	COG0052	Belongs to the universal ribosomal protein uS2 family
B7C62_RS27450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B7C62_RS27455	COG0528	UMP kinase activity
B7C62_RS27460	COG0233	cytoplasmic translational termination
B7C62_RS27475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B7C62_RS27490	COG3842	ATPase activity
B7C62_RS27505	COG4181	ATPase activity
B7C62_RS27510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7C62_RS27520	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS27540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7C62_RS27560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B7C62_RS27565	COG3842	ATPase activity
B7C62_RS27570	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7C62_RS27575	COG1177	transmembrane transport
B7C62_RS27580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7C62_RS27620	COG2508	Transcriptional regulator
B7C62_RS27625	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS27665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B7C62_RS27670	COG0750	zinc metalloprotease
B7C62_RS27675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B7C62_RS27690	COG0442	prolyl-tRNA aminoacylation
B7C62_RS27710	COG0779	Required for maturation of 30S ribosomal subunits
B7C62_RS27725	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B7C62_RS27735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B7C62_RS27740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B7C62_RS27785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7C62_RS27790	COG0601	transmembrane transport
B7C62_RS27795	COG0747	negative chemotaxis
B7C62_RS27820	COG3266	domain, Protein
B7C62_RS27825	COG1404	Belongs to the peptidase S8 family
B7C62_RS27840	COG1404	Belongs to the peptidase S8 family
B7C62_RS27855	COG1674	ftsk spoiiie
B7C62_RS27865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B7C62_RS27870	COG1185	polyribonucleotide nucleotidyltransferase activity
B7C62_RS27875	COG0612	Peptidase, M16
B7C62_RS27880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B7C62_RS27900	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
B7C62_RS27905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7C62_RS27910	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B7C62_RS27940	COG2770	Histidine kinase
B7C62_RS27940	COG2208	phosphoserine phosphatase activity
B7C62_RS27945	COG4999	Histidine kinase
B7C62_RS27945	COG3850	Histidine kinase
B7C62_RS27945	COG3437	response regulator, receiver
B7C62_RS27945	COG2205	protein histidine kinase activity
B7C62_RS27955	COG1674	ftsk spoiiie
B7C62_RS27965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7C62_RS27975	COG1058	Belongs to the CinA family
B7C62_RS27975	COG1546	Belongs to the CinA family
B7C62_RS27980	COG1396	sequence-specific DNA binding
B7C62_RS27985	COG0783	Belongs to the Dps family
B7C62_RS28180	COG1484	DNA-dependent DNA replication
B7C62_RS28250	COG0582	viral genome integration into host DNA
B7C62_RS28265	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS28270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B7C62_RS28275	COG1201	RNA secondary structure unwinding
B7C62_RS28280	COG2207	Transcriptional regulator
B7C62_RS28280	COG1917	Cupin 2, conserved barrel domain protein
B7C62_RS28310	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS28325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B7C62_RS28350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7C62_RS28355	COG0765	amino acid transport
B7C62_RS28360	COG0765	amino acid transport
B7C62_RS28365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7C62_RS28370	COG1126	abc transporter atp-binding protein
B7C62_RS28380	COG2205	protein histidine kinase activity
B7C62_RS28385	COG2358	TRAP transporter, solute receptor (TAXI family
B7C62_RS28390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7C62_RS28405	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B7C62_RS28415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B7C62_RS28420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7C62_RS28430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7C62_RS28475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7C62_RS28480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B7C62_RS28485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7C62_RS28520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7C62_RS28550	COG0577	efflux transmembrane transporter activity
B7C62_RS28550	COG1136	(ABC) transporter
B7C62_RS28555	COG2186	Transcriptional regulator
B7C62_RS28560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7C62_RS28585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7C62_RS28590	COG4565	transcriptional regulatory protein
B7C62_RS28595	COG3290	protein histidine kinase activity
B7C62_RS28605	COG0523	cobalamin synthesis protein
B7C62_RS28610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7C62_RS28615	COG0612	Peptidase, M16
B7C62_RS28630	COG1802	Transcriptional regulator
B7C62_RS28635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7C62_RS28640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7C62_RS28640	COG0045	succinate-CoA ligase (ADP-forming) activity
B7C62_RS28640	COG1042	CoA-binding domain protein
B7C62_RS28655	COG1435	thymidine kinase activity
B7C62_RS28690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B7C62_RS28695	COG0483	inositol monophosphate 1-phosphatase activity
B7C62_RS28705	COG0745	RESPONSE REGULATOR receiver
B7C62_RS28710	COG2205	protein histidine kinase activity
B7C62_RS28735	COG0756	dUTP diphosphatase activity
B7C62_RS28745	COG1136	(ABC) transporter
B7C62_RS28745	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7C62_RS28775	COG0569	domain protein
B7C62_RS28780	COG0531	amino acid
B7C62_RS28785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B7C62_RS28810	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B7C62_RS28820	COG0512	Glutamine amidotransferase of anthranilate synthase
B7C62_RS28830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7C62_RS28835	COG0134	indole-3-glycerol-phosphate synthase activity
B7C62_RS28890	COG2124	cytochrome p450
B7C62_RS28930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7C62_RS28935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS28945	COG2197	response regulator
B7C62_RS28970	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS29000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7C62_RS29020	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS29030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7C62_RS29030	COG0574	Belongs to the PEP-utilizing enzyme family
B7C62_RS29040	COG1278	Cold shock
B7C62_RS29045	COG1280	lysine exporter protein (LysE YggA)
B7C62_RS29050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7C62_RS29055	COG3835	regulator
B7C62_RS29065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7C62_RS29065	COG2080	2 iron, 2 sulfur cluster binding
B7C62_RS29075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS29080	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS29095	COG1132	(ABC) transporter
B7C62_RS29100	COG2375	cellular response to nickel ion
B7C62_RS29100	COG1132	(ABC) transporter
B7C62_RS29110	COG0586	Pfam SNARE associated Golgi protein
B7C62_RS29120	COG1799	cell septum assembly
B7C62_RS29140	COG2040	homocysteine
B7C62_RS29150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7C62_RS29160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B7C62_RS29165	COG0531	amino acid
B7C62_RS29175	COG1024	Enoyl-CoA hydratase
B7C62_RS29210	COG2111	Na H antiporter
B7C62_RS29210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7C62_RS29215	COG1006	Multisubunit Na H antiporter MnhC subunit
B7C62_RS29220	COG0651	ATP synthesis coupled electron transport
B7C62_RS29235	COG1320	monovalent cation:proton antiporter activity
B7C62_RS29250	COG0297	glycogen (starch) synthase activity
B7C62_RS29255	COG0489	protein tyrosine kinase activity
B7C62_RS29295	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B7C62_RS29300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7C62_RS29305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7C62_RS29340	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS29345	COG0477	Major facilitator Superfamily
B7C62_RS29355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7C62_RS29355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7C62_RS29365	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7C62_RS29370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7C62_RS29375	COG3938	Belongs to the proline racemase family
B7C62_RS29380	COG2423	ornithine cyclodeaminase activity
B7C62_RS29385	COG1802	Transcriptional regulator
B7C62_RS29390	COG3291	Pkd domain containing protein
B7C62_RS29405	COG3629	intracellular signal transduction
B7C62_RS29405	COG3903	Transcriptional regulator
B7C62_RS29475	COG1136	(ABC) transporter
B7C62_RS29475	COG0577	efflux transmembrane transporter activity
B7C62_RS29495	COG2217	Heavy metal translocating P-type atpase
B7C62_RS29540	COG1201	RNA secondary structure unwinding
B7C62_RS29590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7C62_RS29595	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7C62_RS29595	COG0596	Alpha beta hydrolase
B7C62_RS29610	COG2814	Major facilitator Superfamily
B7C62_RS29625	COG2801	Transposase and inactivated derivatives
B7C62_RS29625	COG3415	Transposase
B7C62_RS29630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7C62_RS29640	COG0406	alpha-ribazole phosphatase activity
B7C62_RS29650	COG1653	transport
B7C62_RS29655	COG1175	transmembrane transport
B7C62_RS29660	COG0395	ABC-type sugar transport system, permease component
B7C62_RS29665	COG1940	carbohydrate kinase activity
B7C62_RS29670	COG4213	ABC transporter substrate-binding protein
B7C62_RS29680	COG4214	carbohydrate transport
B7C62_RS29685	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B7C62_RS29690	COG0531	amino acid
B7C62_RS29705	COG1316	TRANSCRIPTIONal
B7C62_RS29715	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS29720	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS29725	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS29730	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS29745	COG1024	Enoyl-CoA hydratase
B7C62_RS29745	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7C62_RS29750	COG0183	Belongs to the thiolase family
B7C62_RS29770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B7C62_RS29775	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7C62_RS29785	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B7C62_RS29790	COG3253	May function as heme-dependent peroxidase
B7C62_RS29795	COG0596	Alpha beta hydrolase
B7C62_RS29805	COG3220	belongs to the UPF0276 family
B7C62_RS29875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7C62_RS29880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7C62_RS29940	COG1725	Transcriptional regulator
B7C62_RS29945	COG1131	(ABC) transporter
B7C62_RS29970	COG1063	alcohol dehydrogenase
B7C62_RS29975	COG0156	8-amino-7-oxononanoate synthase activity
B7C62_RS29980	COG0583	DNA-binding transcription factor activity
B7C62_RS29990	COG0346	lactoylglutathione lyase activity
B7C62_RS29995	COG1072	(Pantothenic acid kinase))
B7C62_RS30010	COG2723	6-phospho-beta-galactosidase activity
B7C62_RS30020	COG3409	Peptidoglycan-binding domain 1 protein
B7C62_RS30035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7C62_RS30040	COG0583	DNA-binding transcription factor activity
B7C62_RS30100	COG1175	transmembrane transport
B7C62_RS30120	COG1404	Belongs to the peptidase S8 family
B7C62_RS30135	COG1132	(ABC) transporter
B7C62_RS30140	COG1132	(ABC) transporter
B7C62_RS30150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7C62_RS30160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7C62_RS30165	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7C62_RS30185	COG0529	Catalyzes the synthesis of activated sulfate
B7C62_RS30190	COG0175	sulfate reduction
B7C62_RS30215	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS30235	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7C62_RS30240	COG0583	DNA-binding transcription factor activity
B7C62_RS30245	COG0183	Belongs to the thiolase family
B7C62_RS30290	COG1162	GTPase activity
B7C62_RS30315	COG0028	Belongs to the TPP enzyme family
B7C62_RS30335	COG1802	Transcriptional regulator
B7C62_RS30360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7C62_RS30365	COG2252	PERMEase
B7C62_RS30370	COG3608	succinylglutamate desuccinylase aspartoacylase
B7C62_RS30370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B7C62_RS30410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7C62_RS30435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7C62_RS30445	COG1116	anion transmembrane transporter activity
B7C62_RS30450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS30455	COG1132	(ABC) transporter
B7C62_RS30460	COG0667	Aldo Keto reductase
B7C62_RS30480	COG0435	Glutathione S-transferase
B7C62_RS30495	COG2197	response regulator
B7C62_RS30500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7C62_RS30505	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS30525	COG3960	tartronate-semialdehyde synthase activity
B7C62_RS30545	COG0753	catalase activity
B7C62_RS30550	COG2084	Dehydrogenase
B7C62_RS30555	COG3622	Belongs to the hyi family
B7C62_RS30560	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B7C62_RS30565	COG2188	Transcriptional regulator
B7C62_RS30585	COG2351	hydroxyisourate hydrolase activity
B7C62_RS30595	COG2233	PERMEase
B7C62_RS30605	COG2233	PERMEase
B7C62_RS30640	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B7C62_RS30655	COG2197	response regulator
B7C62_RS30670	COG1136	(ABC) transporter
B7C62_RS30670	COG0577	efflux transmembrane transporter activity
B7C62_RS30675	COG1414	Transcriptional regulator
B7C62_RS30680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7C62_RS30685	COG4266	Belongs to the allantoicase family
B7C62_RS30690	COG0656	L-ascorbic acid biosynthetic process
B7C62_RS30695	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS30740	COG0673	inositol 2-dehydrogenase activity
B7C62_RS30745	COG2188	Transcriptional regulator
B7C62_RS30760	COG1129	ABC transporter
B7C62_RS30765	COG1940	carbohydrate kinase activity
B7C62_RS30775	COG1132	(ABC) transporter
B7C62_RS30780	COG1309	transcriptional regulator
B7C62_RS30785	COG0702	epimerase
B7C62_RS30790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7C62_RS30795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7C62_RS30805	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS30810	COG2207	Transcriptional regulator
B7C62_RS30815	COG2223	nitrite transmembrane transporter activity
B7C62_RS30830	COG1126	abc transporter atp-binding protein
B7C62_RS30835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7C62_RS30840	COG0765	amino acid transport
B7C62_RS30845	COG0765	amino acid transport
B7C62_RS30855	COG1376	ErfK ybiS ycfS ynhG family protein
B7C62_RS30870	COG0405	Gamma-glutamyltransferase
B7C62_RS30905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7C62_RS30910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7C62_RS30920	COG0583	DNA-binding transcription factor activity
B7C62_RS30925	COG0477	Major facilitator Superfamily
B7C62_RS30930	COG3903	Transcriptional regulator
B7C62_RS30930	COG3629	intracellular signal transduction
B7C62_RS30935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS30945	COG0300	oxidoreductase activity
B7C62_RS30955	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS30980	COG0475	glutathione-regulated potassium exporter activity
B7C62_RS31000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS31040	COG0596	Alpha beta hydrolase
B7C62_RS31045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7C62_RS31050	COG1410	methionine synthase
B7C62_RS31050	COG0646	methionine synthase
B7C62_RS31055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B7C62_RS31060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B7C62_RS31095	COG0477	Major facilitator Superfamily
B7C62_RS31140	COG2130	NADP-dependent
B7C62_RS31155	COG0702	epimerase
B7C62_RS31170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7C62_RS31190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7C62_RS31195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7C62_RS31235	COG2197	response regulator
B7C62_RS31260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7C62_RS31270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7C62_RS31305	COG2838	Isocitrate dehydrogenase
B7C62_RS31325	COG0095	Lipoate-protein ligase
B7C62_RS31330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B7C62_RS31340	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B7C62_RS31350	COG1396	sequence-specific DNA binding
B7C62_RS31350	COG3800	Transcriptional regulator
B7C62_RS31365	COG1024	Enoyl-CoA hydratase
B7C62_RS31370	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS31390	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B7C62_RS31405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B7C62_RS31440	COG1131	(ABC) transporter
B7C62_RS31470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7C62_RS31485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B7C62_RS31500	COG1929	Belongs to the glycerate kinase type-1 family
B7C62_RS31525	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7C62_RS31530	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7C62_RS31555	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B7C62_RS31560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B7C62_RS31560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7C62_RS31585	COG1028	Short-chain dehydrogenase reductase Sdr
B7C62_RS31600	COG1834	amidinotransferase
B7C62_RS31610	COG2197	response regulator
B7C62_RS31620	COG4585	Histidine kinase
B7C62_RS31630	COG0515	serine threonine protein kinase
B7C62_RS31630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7C62_RS31645	COG0688	phosphatidylethanolamine metabolic process
B7C62_RS31650	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS31660	COG2301	Belongs to the HpcH HpaI aldolase family
B7C62_RS31665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7C62_RS31665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7C62_RS31670	COG0604	alcohol dehydrogenase
B7C62_RS31685	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7C62_RS31715	COG0583	DNA-binding transcription factor activity
B7C62_RS31720	COG0667	Aldo Keto reductase
B7C62_RS31725	COG2362	D-Aminopeptidase
B7C62_RS31730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7C62_RS31740	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7C62_RS31755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7C62_RS31770	COG2226	methyltransferase
B7C62_RS31790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7C62_RS31815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7C62_RS31830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7C62_RS31830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7C62_RS31840	COG2154	pterin-4-alpha-carbinolamine dehydratase
B7C62_RS31850	COG0702	epimerase
B7C62_RS31860	COG4106	trans-aconitate 2-methyltransferase activity
B7C62_RS31870	COG0656	L-ascorbic acid biosynthetic process
B7C62_RS31880	COG0583	DNA-binding transcription factor activity
B7C62_RS31890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7C62_RS31895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7C62_RS31905	COG1129	ABC transporter
B7C62_RS31910	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7C62_RS31920	COG0673	inositol 2-dehydrogenase activity
B7C62_RS31940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B7C62_RS31990	COG0640	Transcriptional regulator
B7C62_RS32005	COG1129	ABC transporter
B7C62_RS32010	COG1879	ABC-type sugar transport system periplasmic component
B7C62_RS32015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7C62_RS32020	COG1869	D-ribose catabolic process
B7C62_RS32025	COG2318	DinB family
B7C62_RS32050	COG5002	protein histidine kinase activity
B7C62_RS32055	COG0745	RESPONSE REGULATOR receiver
B7C62_RS32070	COG1012	belongs to the aldehyde dehydrogenase family
B7C62_RS32080	COG0517	IMP dehydrogenase activity
B7C62_RS32080	COG4175	Glycine betaine
B7C62_RS32085	COG4176	ABC-type proline glycine betaine transport system permease component
B7C62_RS32110	COG1309	transcriptional regulator
B7C62_RS32125	COG0569	domain protein
B7C62_RS32125	COG2985	domain, Protein
B7C62_RS32140	COG1070	Carbohydrate kinase
B7C62_RS32145	COG2115	Belongs to the xylose isomerase family
B7C62_RS32150	COG1940	carbohydrate kinase activity
B7C62_RS32180	COG1846	Transcriptional regulator
B7C62_RS32210	COG2124	cytochrome p450
B7C62_RS32215	COG1486	melibiose metabolic process
B7C62_RS32250	COG3012	SEC-C Motif Domain Protein
B7C62_RS32270	COG0702	epimerase
B7C62_RS32315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7C62_RS32340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7C62_RS32375	COG2208	phosphoserine phosphatase activity
B7C62_RS32375	COG2770	Histidine kinase
B7C62_RS32385	COG1366	Belongs to the anti-sigma-factor antagonist family
B7C62_RS32395	COG1793	dna ligase
B7C62_RS32430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7C62_RS32480	COG0488	(ABC) transporter
B7C62_RS32505	COG2197	response regulator
B7C62_RS32515	COG1515	deoxyribonuclease V activity
B7C62_RS32525	COG3268	Saccharopine dehydrogenase
B7C62_RS32530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7C62_RS32535	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS32540	COG0183	Belongs to the thiolase family
B7C62_RS32545	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7C62_RS32545	COG1024	Enoyl-CoA hydratase
B7C62_RS32550	COG0789	Transcriptional regulator
B7C62_RS32585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7C62_RS32605	COG0488	(ABC) transporter
B7C62_RS32620	COG1024	Enoyl-CoA hydratase
B7C62_RS32635	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B7C62_RS32665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B7C62_RS32670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7C62_RS32685	COG1134	teichoic acid transport
B7C62_RS32690	COG1562	ergosterol biosynthetic process
B7C62_RS32700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B7C62_RS32710	COG1657	PFAM Prenyltransferase squalene oxidase
B7C62_RS32735	COG2365	Tyrosine phosphatase family
B7C62_RS32745	COG2755	lipolytic protein G-D-S-L family
B7C62_RS32755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7C62_RS32795	COG3467	pyridoxamine 5'-phosphate
B7C62_RS32850	COG3958	Transketolase
B7C62_RS32855	COG3959	Transketolase, thiamine diphosphate binding domain
B7C62_RS32890	COG1132	(ABC) transporter
B7C62_RS32895	COG2375	cellular response to nickel ion
B7C62_RS32895	COG1132	(ABC) transporter
B7C62_RS32900	COG2814	Major facilitator Superfamily
B7C62_RS32910	COG4221	oxidoreductase activity
B7C62_RS32935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS32945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7C62_RS32950	COG1120	ATPase activity
B7C62_RS32955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS32960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS32975	COG0714	Associated with various cellular activities
B7C62_RS33000	COG3511	phospholipase C
B7C62_RS33010	COG2197	response regulator
B7C62_RS33015	COG3851	Histidine kinase
B7C62_RS33040	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B7C62_RS33040	COG1672	PFAM Archaeal ATPase
B7C62_RS33050	COG0318	PFAM AMP-dependent synthetase and ligase
B7C62_RS33060	COG0156	8-amino-7-oxononanoate synthase activity
B7C62_RS33075	COG3321	synthase
B7C62_RS33075	COG0604	alcohol dehydrogenase
B7C62_RS33085	COG0604	alcohol dehydrogenase
B7C62_RS33085	COG3321	synthase
B7C62_RS33090	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7C62_RS33115	COG3629	intracellular signal transduction
B7C62_RS33115	COG3903	Transcriptional regulator
B7C62_RS33155	COG1051	belongs to the nudix hydrolase family
B7C62_RS33195	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7C62_RS33195	COG1902	pentaerythritol trinitrate reductase activity
B7C62_RS33210	COG2409	Drug exporters of the RND superfamily
B7C62_RS33215	COG1846	Transcriptional regulator
B7C62_RS33265	COG1233	COG1233 Phytoene dehydrogenase and related
B7C62_RS33270	COG2130	NADP-dependent
B7C62_RS33315	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B7C62_RS33325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7C62_RS33335	COG0019	diaminopimelate decarboxylase activity
B7C62_RS33345	COG2837	iron assimilation
B7C62_RS33350	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS33355	COG1794	racemase activity, acting on amino acids and derivatives
B7C62_RS33365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS33370	COG0367	asparagine synthase
B7C62_RS33375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS33380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS33405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS33435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B7C62_RS33480	COG0395	ABC-type sugar transport system, permease component
B7C62_RS33485	COG1175	transmembrane transport
B7C62_RS33495	COG1940	carbohydrate kinase activity
B7C62_RS33545	COG0784	Response regulator, receiver
B7C62_RS33550	COG4251	negative regulation of phosphorylation
B7C62_RS33555	COG2201	protein-glutamate methylesterase activity
B7C62_RS33560	COG1191	sigma factor activity
B7C62_RS33600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B7C62_RS33620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7C62_RS33625	COG3275	phosphorelay sensor kinase activity
B7C62_RS33705	COG0583	DNA-binding transcription factor activity
B7C62_RS33715	COG1053	succinate dehydrogenase
B7C62_RS33720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7C62_RS33740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7C62_RS33750	COG3360	Dodecin
B7C62_RS33770	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B7C62_RS33775	COG0121	glutamine amidotransferase
B7C62_RS33780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7C62_RS33795	COG1609	Transcriptional regulator
B7C62_RS33805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7C62_RS33810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7C62_RS33825	COG1902	pentaerythritol trinitrate reductase activity
B7C62_RS33860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B7C62_RS33865	COG1834	amidinotransferase
B7C62_RS33880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7C62_RS33895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7C62_RS33940	COG0477	Major facilitator Superfamily
B7C62_RS33975	COG1120	ATPase activity
B7C62_RS33985	COG0477	Major facilitator Superfamily
B7C62_RS33990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B7C62_RS34000	COG0254	rRNA binding
B7C62_RS34005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B7C62_RS34010	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B7C62_RS34015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B7C62_RS34035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS34040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS34045	COG1120	ATPase activity
B7C62_RS34070	COG1132	(ABC) transporter
B7C62_RS34075	COG1132	(ABC) transporter
B7C62_RS34120	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS34130	COG0728	peptidoglycan biosynthetic process
B7C62_RS34145	COG0438	transferase activity, transferring glycosyl groups
B7C62_RS34145	COG0297	glycogen (starch) synthase activity
B7C62_RS34175	COG1174	glycine betaine transport
B7C62_RS34180	COG1174	glycine betaine transport
B7C62_RS34200	COG0517	IMP dehydrogenase activity
B7C62_RS34200	COG1125	glycine betaine transport
B7C62_RS34230	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS34235	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS34245	COG0601	transmembrane transport
B7C62_RS34250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7C62_RS34255	COG0444	Belongs to the ABC transporter superfamily
B7C62_RS34315	COG1796	DNA polymerase
B7C62_RS34315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B7C62_RS34390	COG1278	Cold shock
B7C62_RS34405	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B7C62_RS34420	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B7C62_RS34455	COG0375	protein maturation
B7C62_RS34460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B7C62_RS34465	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B7C62_RS34470	COG0298	carbon dioxide binding
B7C62_RS34475	COG0409	Hydrogenase expression formation protein
B7C62_RS34490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS34495	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7C62_RS34505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7C62_RS34510	COG0596	Alpha beta hydrolase
B7C62_RS34520	COG1132	(ABC) transporter
B7C62_RS34525	COG4044	May play a role in the intracellular transport of hydrophobic ligands
B7C62_RS34545	COG0493	'glutamate synthase
B7C62_RS34545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7C62_RS34565	COG2175	clavaminate synthase activity
B7C62_RS34575	COG2080	2 iron, 2 sulfur cluster binding
B7C62_RS34580	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B7C62_RS34585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7C62_RS34595	COG1960	acyl-CoA dehydrogenase activity
B7C62_RS34600	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7C62_RS34610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7C62_RS34615	COG3239	Fatty acid desaturase
B7C62_RS34645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7C62_RS34650	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7C62_RS34655	COG0640	Transcriptional regulator
B7C62_RS34670	COG2018	Roadblock/LC7 domain
B7C62_RS34695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B7C62_RS34735	COG1595	DNA-templated transcription, initiation
B7C62_RS34750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7C62_RS34755	COG2197	response regulator
B7C62_RS34760	COG3851	Histidine kinase
B7C62_RS34770	COG1131	(ABC) transporter
B7C62_RS34775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7C62_RS34795	COG2340	Cysteine-rich secretory protein family
B7C62_RS34830	COG0488	(ABC) transporter
B7C62_RS34845	COG0009	L-threonylcarbamoyladenylate synthase
B7C62_RS34890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7C62_RS34900	COG3321	synthase
B7C62_RS34900	COG0604	alcohol dehydrogenase
B7C62_RS34900	COG1028	Short-chain dehydrogenase reductase Sdr