locus-tag	class	description
CP975_RS00030	COG1793	dna ligase
CP975_RS00110	COG0443	Heat shock 70 kDa protein
CP975_RS00135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP975_RS00145	COG0477	Major facilitator Superfamily
CP975_RS00160	COG3655	Transcriptional regulator
CP975_RS00190	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP975_RS00195	COG2808	Putative FMN-binding domain
CP975_RS00230	COG3321	synthase
CP975_RS00230	COG0604	alcohol dehydrogenase
CP975_RS00245	COG2124	cytochrome p450
CP975_RS00335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS00350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS00355	COG2986	histidine ammonia-lyase
CP975_RS00360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CP975_RS00365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS00450	COG0473	3-isopropylmalate dehydrogenase activity
CP975_RS00455	COG0583	DNA-binding transcription factor activity
CP975_RS00470	COG2910	NAD(P)H-binding
CP975_RS00495	COG2207	Transcriptional regulator
CP975_RS00495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP975_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS00625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP975_RS00625	COG0515	serine threonine protein kinase
CP975_RS00630	COG0515	serine threonine protein kinase
CP975_RS00630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP975_RS00655	COG0515	serine threonine protein kinase
CP975_RS00695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP975_RS00700	COG1090	epimerase
CP975_RS00705	COG2197	response regulator
CP975_RS00715	COG1090	epimerase
CP975_RS00730	COG0583	DNA-binding transcription factor activity
CP975_RS00750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP975_RS00775	COG2084	Dehydrogenase
CP975_RS00785	COG0142	geranyltranstransferase activity
CP975_RS00795	COG1902	pentaerythritol trinitrate reductase activity
CP975_RS00805	COG1309	transcriptional regulator
CP975_RS00840	COG3540	Alkaline phosphatase
CP975_RS00860	COG1733	regulation of RNA biosynthetic process
CP975_RS00880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP975_RS00885	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP975_RS00895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP975_RS00910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP975_RS00920	COG2814	Major facilitator Superfamily
CP975_RS00950	COG2755	lipolytic protein G-D-S-L family
CP975_RS00970	COG2816	NAD+ diphosphatase activity
CP975_RS00975	COG0456	acetyltransferase
CP975_RS01045	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS01060	COG1597	lipid kinase activity
CP975_RS01065	COG0477	Major facilitator Superfamily
CP975_RS01070	COG0300	oxidoreductase activity
CP975_RS01080	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS01115	COG1404	Belongs to the peptidase S8 family
CP975_RS01120	COG1309	transcriptional regulator
CP975_RS01125	COG0596	Alpha beta hydrolase
CP975_RS01130	COG0667	Aldo Keto reductase
CP975_RS01160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP975_RS01180	COG0009	L-threonylcarbamoyladenylate synthase
CP975_RS01210	COG1295	ribonuclease BN
CP975_RS01240	COG0693	protein deglycase activity
CP975_RS01265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP975_RS01285	COG1595	DNA-templated transcription, initiation
CP975_RS01350	COG2340	Cysteine-rich secretory protein family
CP975_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS01390	COG1309	transcriptional regulator
CP975_RS01395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP975_RS01405	COG2755	lipolytic protein G-D-S-L family
CP975_RS01425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP975_RS01440	COG0702	epimerase
CP975_RS01445	COG1733	regulation of RNA biosynthetic process
CP975_RS01450	COG2409	Drug exporters of the RND superfamily
CP975_RS01470	COG2226	methyltransferase
CP975_RS01505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP975_RS01515	COG2409	Drug exporters of the RND superfamily
CP975_RS01535	COG4941	Belongs to the sigma-70 factor family
CP975_RS01540	COG0583	DNA-binding transcription factor activity
CP975_RS01555	COG0367	asparagine synthase
CP975_RS01590	COG1960	acyl-CoA dehydrogenase activity
CP975_RS01600	COG0242	peptide deformylase activity
CP975_RS01610	COG3442	glutamine amidotransferase
CP975_RS01615	COG0205	6-phosphofructokinase activity
CP975_RS01635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP975_RS01650	COG4566	intracellular signal transduction
CP975_RS01655	COG1672	PFAM Archaeal ATPase
CP975_RS01655	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP975_RS01670	COG1082	Xylose isomerase domain protein TIM barrel
CP975_RS01705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP975_RS01710	COG0477	Major facilitator Superfamily
CP975_RS01720	COG0829	nickel cation binding
CP975_RS01725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP975_RS01735	COG0804	urea catabolic process
CP975_RS01740	COG0832	Belongs to the urease beta subunit family
CP975_RS01745	COG0831	urea catabolic process
CP975_RS01750	COG1309	transcriptional regulator
CP975_RS01765	COG0740	serine-type endopeptidase activity
CP975_RS01775	COG0791	NLP P60 protein
CP975_RS01780	COG1280	lysine exporter protein (LysE YggA)
CP975_RS01785	COG0583	DNA-binding transcription factor activity
CP975_RS01810	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP975_RS01815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP975_RS01820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP975_RS01825	COG2226	methyltransferase
CP975_RS01840	COG1136	(ABC) transporter
CP975_RS01840	COG0577	efflux transmembrane transporter activity
CP975_RS01845	COG0577	efflux transmembrane transporter activity
CP975_RS01845	COG1136	(ABC) transporter
CP975_RS01850	COG0456	acetyltransferase
CP975_RS01870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP975_RS01900	COG1024	Enoyl-CoA hydratase
CP975_RS01910	COG1940	carbohydrate kinase activity
CP975_RS01915	COG2188	Transcriptional regulator
CP975_RS01920	COG1595	DNA-templated transcription, initiation
CP975_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS01965	COG1522	sequence-specific DNA binding
CP975_RS01995	COG0277	FAD linked oxidase domain protein
CP975_RS02000	COG1191	sigma factor activity
CP975_RS02025	COG0419	ATPase involved in DNA repair
CP975_RS02030	COG0420	3'-5' exonuclease activity
CP975_RS02035	COG1739	Uncharacterized protein family UPF0029
CP975_RS02080	COG1132	(ABC) transporter
CP975_RS02105	COG1832	CoA-binding protein
CP975_RS02130	COG0542	response to heat
CP975_RS02145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP975_RS02155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP975_RS02155	COG0723	plastoquinol--plastocyanin reductase activity
CP975_RS02165	COG3608	succinylglutamate desuccinylase aspartoacylase
CP975_RS02165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CP975_RS02170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP975_RS02175	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP975_RS02180	COG2080	2 iron, 2 sulfur cluster binding
CP975_RS02205	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS02215	COG3629	intracellular signal transduction
CP975_RS02215	COG3903	Transcriptional regulator
CP975_RS02235	COG0714	Associated with various cellular activities
CP975_RS02245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP975_RS02265	COG0432	Pfam Uncharacterised protein family UPF0047
CP975_RS02270	COG2072	flavoprotein involved in K transport
CP975_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS02315	COG1132	(ABC) transporter
CP975_RS02320	COG1846	Transcriptional regulator
CP975_RS02325	COG0277	FAD linked oxidase domain protein
CP975_RS02345	COG1132	(ABC) transporter
CP975_RS02350	COG1132	(ABC) transporter
CP975_RS02355	COG1132	(ABC) transporter
CP975_RS02370	COG1946	Acyl-CoA thioesterase
CP975_RS02390	COG2018	Roadblock/LC7 domain
CP975_RS02460	COG3239	Fatty acid desaturase
CP975_RS02465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP975_RS02485	COG1940	carbohydrate kinase activity
CP975_RS02500	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS02535	COG2211	Major facilitator Superfamily
CP975_RS02550	COG0156	8-amino-7-oxononanoate synthase activity
CP975_RS02560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS02570	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS02610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CP975_RS02615	COG1335	isochorismatase
CP975_RS02620	COG2259	Doxx family
CP975_RS02625	COG2267	carboxylic ester hydrolase activity
CP975_RS02690	COG1203	CRISPR-associated helicase, Cas3
CP975_RS02730	COG0443	Heat shock 70 kDa protein
CP975_RS02850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP975_RS02935	COG3693	PFAM glycoside hydrolase, family 10
CP975_RS02965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP975_RS02995	COG3251	PFAM MbtH domain protein
CP975_RS03015	COG2124	cytochrome p450
CP975_RS03045	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP975_RS03055	COG0326	Molecular chaperone. Has ATPase activity
CP975_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS03065	COG2814	Major facilitator Superfamily
CP975_RS03090	COG1454	alcohol dehydrogenase
CP975_RS03095	COG0028	Belongs to the TPP enzyme family
CP975_RS03095	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CP975_RS03110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CP975_RS03115	COG1929	Belongs to the glycerate kinase type-1 family
CP975_RS03125	COG1966	Carbon starvation protein
CP975_RS03155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS03160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS03170	COG2175	clavaminate synthase activity
CP975_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS03210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP975_RS03230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP975_RS03245	COG1216	Glycosyl transferase, family 2
CP975_RS03255	COG4310	Domain of unknown function (DUF2172)
CP975_RS03270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP975_RS03280	COG0438	transferase activity, transferring glycosyl groups
CP975_RS03300	COG0673	inositol 2-dehydrogenase activity
CP975_RS03305	COG0367	asparagine synthase
CP975_RS03320	COG0438	transferase activity, transferring glycosyl groups
CP975_RS03325	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP975_RS03365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS03370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS03375	COG0789	Transcriptional regulator
CP975_RS03385	COG0583	DNA-binding transcription factor activity
CP975_RS03390	COG1271	oxidase subunit
CP975_RS03400	COG4988	ABC transporter
CP975_RS03405	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CP975_RS03410	COG4638	Rieske (2fe-2S)
CP975_RS03420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP975_RS03445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS03450	COG0483	inositol monophosphate 1-phosphatase activity
CP975_RS03465	COG1191	sigma factor activity
CP975_RS03490	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP975_RS03495	COG3281	Trehalose synthase
CP975_RS03505	COG0366	Alpha amylase catalytic
CP975_RS03540	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS03545	COG0659	secondary active sulfate transmembrane transporter activity
CP975_RS03555	COG0659	secondary active sulfate transmembrane transporter activity
CP975_RS03695	COG0444	Belongs to the ABC transporter superfamily
CP975_RS03700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP975_RS03705	COG0601	transmembrane transport
CP975_RS03715	COG1960	acyl-CoA dehydrogenase activity
CP975_RS03720	COG1960	acyl-CoA dehydrogenase activity
CP975_RS03735	COG0492	ferredoxin-NADP+ reductase activity
CP975_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS03745	COG1024	Enoyl-CoA hydratase
CP975_RS03765	COG1139	Iron-sulfur cluster binding protein
CP975_RS03770	COG1556	Lactate utilization protein
CP975_RS03785	COG1174	glycine betaine transport
CP975_RS03790	COG1174	glycine betaine transport
CP975_RS03810	COG2376	Dihydroxyacetone kinase
CP975_RS03815	COG1461	Dihydroxyacetone kinase
CP975_RS03830	COG1695	Transcriptional regulator
CP975_RS03850	COG1902	pentaerythritol trinitrate reductase activity
CP975_RS03850	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP975_RS03875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS03890	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CP975_RS03895	COG2813	Specifically methylates the guanine in position
CP975_RS03915	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CP975_RS03920	COG1215	transferase activity, transferring glycosyl groups
CP975_RS04015	COG1940	carbohydrate kinase activity
CP975_RS04050	COG0445	tRNA wobble uridine modification
CP975_RS04060	COG1660	Displays ATPase and GTPase activities
CP975_RS04075	COG3345	alpha-galactosidase
CP975_RS04100	COG0515	serine threonine protein kinase
CP975_RS04115	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP975_RS04135	COG0204	Acyl-transferase
CP975_RS04170	COG1191	sigma factor activity
CP975_RS04185	COG1366	Belongs to the anti-sigma-factor antagonist family
CP975_RS04190	COG1366	Belongs to the anti-sigma-factor antagonist family
CP975_RS04195	COG2172	sigma factor antagonist activity
CP975_RS04205	COG2208	phosphoserine phosphatase activity
CP975_RS04205	COG2770	Histidine kinase
CP975_RS04210	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CP975_RS04245	COG0488	(ABC) transporter
CP975_RS04250	COG2376	Dihydroxyacetone kinase
CP975_RS04260	COG1597	lipid kinase activity
CP975_RS04270	COG0584	glycerophosphoryl diester phosphodiesterase
CP975_RS04285	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP975_RS04295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP975_RS04310	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS04315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP975_RS04325	COG1846	Transcriptional regulator
CP975_RS04350	COG0671	phosphoesterase, PA-phosphatase related
CP975_RS04360	COG1309	transcriptional regulator
CP975_RS04370	COG0640	Transcriptional regulator
CP975_RS04375	COG1902	pentaerythritol trinitrate reductase activity
CP975_RS04395	COG1940	carbohydrate kinase activity
CP975_RS04410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP975_RS04420	COG2040	homocysteine
CP975_RS04430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP975_RS04445	COG2706	6-phosphogluconolactonase activity
CP975_RS04465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CP975_RS04485	COG4249	Peptidase C14 caspase catalytic subunit p20
CP975_RS04485	COG2319	Wd-40 repeat
CP975_RS04490	COG2326	polyphosphate kinase activity
CP975_RS04500	COG2409	Drug exporters of the RND superfamily
CP975_RS04560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP975_RS04595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP975_RS04600	COG1960	acyl-CoA dehydrogenase activity
CP975_RS04660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP975_RS04675	COG0183	Belongs to the thiolase family
CP975_RS04685	COG1968	undecaprenyl-diphosphatase activity
CP975_RS04700	COG0494	nUDIX hydrolase
CP975_RS04715	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP975_RS04755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP975_RS04805	COG0697	spore germination
CP975_RS04840	COG2890	protein-(glutamine-N5) methyltransferase activity
CP975_RS04850	COG1695	Transcriptional regulator
CP975_RS04855	COG0384	phenazine biosynthesis protein PhzF
CP975_RS04885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP975_RS04885	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP975_RS04895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP975_RS04915	COG1716	ATPase activity
CP975_RS04935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP975_RS04970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP975_RS04980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP975_RS04995	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CP975_RS05010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP975_RS05015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP975_RS05050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP975_RS05060	COG1414	Transcriptional regulator
CP975_RS05075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP975_RS05105	COG2814	Major facilitator Superfamily
CP975_RS05110	COG4336	lyase activity
CP975_RS05115	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP975_RS05120	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP975_RS05125	COG1984	allophanate hydrolase subunit 2
CP975_RS05165	COG2270	Major facilitator Superfamily
CP975_RS05180	COG0463	Glycosyl transferase, family 2
CP975_RS05215	COG1960	acyl-CoA dehydrogenase activity
CP975_RS05225	COG1309	transcriptional regulator
CP975_RS05260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP975_RS05260	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP975_RS05285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP975_RS05290	COG0140	phosphoribosyl-ATP diphosphatase activity
CP975_RS05295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP975_RS05300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP975_RS05300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP975_RS05305	COG3201	nicotinamide mononucleotide transporter
CP975_RS05325	COG0702	epimerase
CP975_RS05330	COG1846	Transcriptional regulator
CP975_RS05330	COG1940	carbohydrate kinase activity
CP975_RS05335	COG0738	Major facilitator superfamily
CP975_RS05340	COG2233	PERMEase
CP975_RS05360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP975_RS05375	COG0531	amino acid
CP975_RS05395	COG2390	Transcriptional regulator
CP975_RS05400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP975_RS05410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP975_RS05425	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP975_RS05440	COG0194	GDP metabolic process
CP975_RS05450	COG0284	orotidine-5'-phosphate decarboxylase activity
CP975_RS05455	COG0167	dihydroorotate dehydrogenase activity
CP975_RS05460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP975_RS05465	COG0505	Belongs to the CarA family
CP975_RS05475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP975_RS05480	COG0540	Belongs to the ATCase OTCase family
CP975_RS05485	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP975_RS05495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP975_RS05500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP975_RS05505	COG0006	proline dipeptidase activity
CP975_RS05515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP975_RS05520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP975_RS05525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP975_RS05530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP975_RS05535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP975_RS05540	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP975_RS05545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP975_RS05565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP975_RS05580	COG1131	(ABC) transporter
CP975_RS05590	COG4585	Histidine kinase
CP975_RS05595	COG2197	response regulator
CP975_RS05600	COG0124	histidyl-tRNA synthetase
CP975_RS05610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP975_RS05615	COG1196	nuclear chromosome segregation
CP975_RS05620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP975_RS05625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP975_RS05630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP975_RS05635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP975_RS05645	COG2255	four-way junction helicase activity
CP975_RS05650	COG0632	four-way junction helicase activity
CP975_RS05655	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP975_RS05660	COG0217	transcriptional regulatory protein
CP975_RS05665	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP975_RS05670	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP975_RS05680	COG0438	transferase activity, transferring glycosyl groups
CP975_RS05685	COG1560	Kdo2-lipid A biosynthetic process
CP975_RS05690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP975_RS05710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP975_RS05725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP975_RS05780	COG0454	-acetyltransferase
CP975_RS05780	COG0456	acetyltransferase
CP975_RS05785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP975_RS05790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP975_RS05790	COG0512	Glutamine amidotransferase of anthranilate synthase
CP975_RS05850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP975_RS05850	COG1648	precorrin-2 dehydrogenase activity
CP975_RS05855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP975_RS05870	COG1464	Belongs to the NlpA lipoprotein family
CP975_RS05875	COG1464	Belongs to the NlpA lipoprotein family
CP975_RS05880	COG2011	ABC-type metal ion transport system permease component
CP975_RS05885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP975_RS05920	COG0584	glycerophosphoryl diester phosphodiesterase
CP975_RS05925	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS05925	COG0204	Acyl-transferase
CP975_RS05930	COG0477	Major facilitator Superfamily
CP975_RS05945	COG0165	Argininosuccinate lyase
CP975_RS05955	COG0385	Bile acid
CP975_RS05960	COG1438	arginine binding
CP975_RS05965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP975_RS05970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP975_RS05975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP975_RS05980	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP975_RS05995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP975_RS06020	COG0477	Major facilitator Superfamily
CP975_RS06030	COG0667	Aldo Keto reductase
CP975_RS06045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP975_RS06050	COG0697	spore germination
CP975_RS06060	COG1649	PFAM Uncharacterised BCR, COG1649
CP975_RS06090	COG0072	phenylalanine-tRNA ligase activity
CP975_RS06090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP975_RS06095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP975_RS06100	COG5002	protein histidine kinase activity
CP975_RS06105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP975_RS06110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP975_RS06115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP975_RS06120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP975_RS06155	COG0560	Phosphoserine phosphatase
CP975_RS06155	COG3830	Belongs to the UPF0237 family
CP975_RS06165	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS06170	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS06175	COG0174	glutamine synthetase
CP975_RS06185	COG0531	amino acid
CP975_RS06190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP975_RS06220	COG4176	ABC-type proline glycine betaine transport system permease component
CP975_RS06225	COG0517	IMP dehydrogenase activity
CP975_RS06225	COG4175	Glycine betaine
CP975_RS06230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP975_RS06285	COG0805	protein transport
CP975_RS06290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP975_RS06310	COG2378	regulation of single-species biofilm formation
CP975_RS06320	COG0545	Peptidyl-prolyl cis-trans isomerase
CP975_RS06325	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP975_RS06335	COG1609	Transcriptional regulator
CP975_RS06340	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP975_RS06345	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP975_RS06360	COG4122	O-methyltransferase activity
CP975_RS06365	COG1222	aaa ATPase
CP975_RS06395	COG1994	Peptidase M50
CP975_RS06395	COG0517	IMP dehydrogenase activity
CP975_RS06405	COG2197	response regulator
CP975_RS06410	COG0747	negative chemotaxis
CP975_RS06415	COG0747	negative chemotaxis
CP975_RS06420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP975_RS06425	COG0646	methionine synthase
CP975_RS06425	COG1410	methionine synthase
CP975_RS06430	COG1414	Transcriptional regulator
CP975_RS06435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP975_RS06440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP975_RS06445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP975_RS06450	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CP975_RS06455	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CP975_RS06460	COG0235	Class ii aldolase
CP975_RS06465	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP975_RS06465	COG0235	Class ii aldolase
CP975_RS06470	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CP975_RS06475	COG0402	S-adenosylhomocysteine deaminase activity
CP975_RS06480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP975_RS06490	COG2186	Transcriptional regulator
CP975_RS06500	COG4935	Belongs to the peptidase S8 family
CP975_RS06500	COG1404	Belongs to the peptidase S8 family
CP975_RS06515	COG0215	cysteine-tRNA ligase activity
CP975_RS06535	COG0598	Magnesium transport protein CorA
CP975_RS06545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP975_RS06550	COG0667	Aldo Keto reductase
CP975_RS06580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP975_RS06590	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP975_RS06595	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP975_RS06600	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP975_RS06610	COG0531	amino acid
CP975_RS06625	COG0028	Belongs to the TPP enzyme family
CP975_RS06635	COG0753	catalase activity
CP975_RS06640	COG3012	SEC-C Motif Domain Protein
CP975_RS06645	COG2186	Transcriptional regulator
CP975_RS06650	COG3265	gluconokinase activity
CP975_RS06670	COG3573	Dehydrogenase
CP975_RS06675	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP975_RS06680	COG2149	membrane
CP975_RS06690	COG0477	Major facilitator Superfamily
CP975_RS06695	COG2197	response regulator
CP975_RS06700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP975_RS06710	COG0477	Major facilitator Superfamily
CP975_RS06740	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS06755	COG0477	Major facilitator Superfamily
CP975_RS06780	COG0789	Transcriptional regulator
CP975_RS06800	COG1960	acyl-CoA dehydrogenase activity
CP975_RS06835	COG4941	Belongs to the sigma-70 factor family
CP975_RS06840	COG3795	YCII-related domain
CP975_RS06855	COG2851	Citrate transporter
CP975_RS06860	COG0243	molybdopterin cofactor binding
CP975_RS06865	COG1309	transcriptional regulator
CP975_RS06870	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CP975_RS06875	COG2188	Transcriptional regulator
CP975_RS06890	COG0515	serine threonine protein kinase
CP975_RS06895	COG2755	lipolytic protein G-D-S-L family
CP975_RS06910	COG0463	Glycosyl transferase, family 2
CP975_RS06920	COG0726	polysaccharide deacetylase
CP975_RS06920	COG1649	PFAM Uncharacterised BCR, COG1649
CP975_RS06945	COG1725	Transcriptional regulator
CP975_RS06960	COG2226	methyltransferase
CP975_RS06980	COG4565	transcriptional regulatory protein
CP975_RS07025	COG0587	DNA-directed DNA polymerase activity
CP975_RS07045	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CP975_RS07070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP975_RS07100	COG0330	HflC and HflK could
CP975_RS07120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP975_RS07125	COG1126	abc transporter atp-binding protein
CP975_RS07135	COG0765	amino acid transport
CP975_RS07140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP975_RS07150	COG1799	cell septum assembly
CP975_RS07155	COG1960	acyl-CoA dehydrogenase activity
CP975_RS07160	COG0477	Major facilitator Superfamily
CP975_RS07170	COG0671	phosphoesterase, PA-phosphatase related
CP975_RS07180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP975_RS07195	COG0438	transferase activity, transferring glycosyl groups
CP975_RS07215	COG1137	ATPase activity
CP975_RS07225	COG3583	domain protein
CP975_RS07230	COG1652	LysM domain
CP975_RS07245	COG1160	GTP binding
CP975_RS07255	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP975_RS07285	COG1187	pseudouridine synthase activity
CP975_RS07290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP975_RS07295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP975_RS07310	COG0686	Belongs to the AlaDH PNT family
CP975_RS07320	COG0494	nUDIX hydrolase
CP975_RS07325	COG0504	CTP synthase activity
CP975_RS07330	COG3387	PFAM Glycoside hydrolase 15-related
CP975_RS07340	COG0438	transferase activity, transferring glycosyl groups
CP975_RS07345	COG0497	DNA recombination
CP975_RS07355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP975_RS07375	COG1120	ATPase activity
CP975_RS07380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS07385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS07400	COG0647	UMP catabolic process
CP975_RS07430	COG2094	Belongs to the DNA glycosylase MPG family
CP975_RS07440	COG1881	PFAM PEBP family protein
CP975_RS07460	COG1119	ATPase activity
CP975_RS07480	COG2197	response regulator
CP975_RS07495	COG1716	ATPase activity
CP975_RS07495	COG0842	Transport permease protein
CP975_RS07495	COG1131	(ABC) transporter
CP975_RS07505	COG0560	Phosphoserine phosphatase
CP975_RS07505	COG3830	Belongs to the UPF0237 family
CP975_RS07525	COG2807	transmembrane transport
CP975_RS07530	COG2186	Transcriptional regulator
CP975_RS07540	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP975_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS07560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP975_RS07580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP975_RS07585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP975_RS07665	COG3387	PFAM Glycoside hydrolase 15-related
CP975_RS07715	COG0488	(ABC) transporter
CP975_RS07750	COG0235	Class ii aldolase
CP975_RS07770	COG1492	cobalamin metabolic process
CP975_RS07785	COG1797	cobyrinic acid a,c-diamide synthase activity
CP975_RS07800	COG1231	oxidoreductase activity
CP975_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS07830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CP975_RS07835	COG2318	DinB family
CP975_RS07840	COG0456	acetyltransferase
CP975_RS07845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP975_RS07850	COG1917	Cupin 2, conserved barrel domain protein
CP975_RS07855	COG5285	phytanoyl-CoA dioxygenase
CP975_RS07860	COG1902	pentaerythritol trinitrate reductase activity
CP975_RS07865	COG1846	Transcriptional regulator
CP975_RS07870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP975_RS07880	COG1733	regulation of RNA biosynthetic process
CP975_RS07885	COG0673	inositol 2-dehydrogenase activity
CP975_RS07895	COG1414	Transcriptional regulator
CP975_RS07910	COG4585	Histidine kinase
CP975_RS07915	COG2197	response regulator
CP975_RS07920	COG0768	penicillin binding
CP975_RS07930	COG1695	Transcriptional regulator
CP975_RS07955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP975_RS07960	COG1349	DNA-binding transcription factor activity
CP975_RS07995	COG0515	serine threonine protein kinase
CP975_RS07995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP975_RS08030	COG2329	Antibiotic biosynthesis monooxygenase
CP975_RS08065	COG1595	DNA-templated transcription, initiation
CP975_RS08075	COG2171	N-acyltransferase activity
CP975_RS08080	COG3226	Transcriptional regulator
CP975_RS08100	COG0822	iron-sulfur transferase activity
CP975_RS08105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP975_RS08110	COG0396	ATPase activity
CP975_RS08120	COG0719	Fe-S assembly protein
CP975_RS08145	COG1612	heme a metabolic process
CP975_RS08160	COG0109	protoheme IX farnesyltransferase activity
CP975_RS08170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP975_RS08185	COG0363	glucosamine-6-phosphate deaminase activity
CP975_RS08195	COG0166	Belongs to the GPI family
CP975_RS08205	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP975_RS08210	COG0149	triose-phosphate isomerase activity
CP975_RS08215	COG0126	phosphoglycerate kinase activity
CP975_RS08220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP975_RS08230	COG1481	regulation of sporulation
CP975_RS08235	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP975_RS08240	COG1660	Displays ATPase and GTPase activities
CP975_RS08245	COG0322	excinuclease ABC activity
CP975_RS08270	COG1105	Belongs to the carbohydrate kinase PfkB family
CP975_RS08275	COG1024	Enoyl-CoA hydratase
CP975_RS08280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP975_RS08290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP975_RS08295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP975_RS08300	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP975_RS08305	COG0477	Major facilitator Superfamily
CP975_RS08310	COG0387	Pfam Sodium calcium exchanger
CP975_RS08330	COG0556	nucleotide-excision repair
CP975_RS08340	COG0584	glycerophosphoryl diester phosphodiesterase
CP975_RS08345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP975_RS08360	COG2313	pseudouridylate synthase activity
CP975_RS08370	COG2226	methyltransferase
CP975_RS08375	COG0598	Magnesium transport protein CorA
CP975_RS08440	COG0402	S-adenosylhomocysteine deaminase activity
CP975_RS08470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP975_RS08490	COG0251	oxidation-reduction process
CP975_RS08515	COG1288	antiporter activity
CP975_RS08550	COG0237	dephospho-CoA kinase activity
CP975_RS08570	COG1643	Atp-dependent helicase
CP975_RS08600	COG2050	protein possibly involved in aromatic compounds catabolism
CP975_RS08670	COG0737	Belongs to the 5'-nucleotidase family
CP975_RS08685	COG0702	epimerase
CP975_RS08695	COG1605	Chorismate mutase
CP975_RS08695	COG0287	Prephenate dehydrogenase
CP975_RS08710	COG0366	Alpha amylase catalytic
CP975_RS08710	COG1470	cell adhesion involved in biofilm formation
CP975_RS08725	COG1357	PFAM Pentapeptide repeats (8 copies)
CP975_RS08735	COG1278	Cold shock
CP975_RS08740	COG2365	Tyrosine phosphatase family
CP975_RS08760	COG0395	ABC-type sugar transport system, permease component
CP975_RS08765	COG1175	transmembrane transport
CP975_RS08780	COG0069	glutamate synthase activity
CP975_RS08780	COG0067	glutamate synthase
CP975_RS08780	COG0070	glutamate synthase
CP975_RS08790	COG1397	ADP-ribosylglycohydrolase
CP975_RS08810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP975_RS08815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP975_RS08825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CP975_RS08835	COG0159	tryptophan synthase activity
CP975_RS08840	COG0133	tryptophan synthase activity
CP975_RS08845	COG0134	indole-3-glycerol-phosphate synthase activity
CP975_RS08865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP975_RS08870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP975_RS08880	COG0107	imidazoleglycerol-phosphate synthase activity
CP975_RS08885	COG0251	oxidation-reduction process
CP975_RS08890	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP975_RS08895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP975_RS08900	COG0131	Imidazoleglycerol-phosphate dehydratase
CP975_RS08905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP975_RS08910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP975_RS08930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP975_RS08950	COG1432	Conserved Protein
CP975_RS08960	COG0587	DNA-directed DNA polymerase activity
CP975_RS09010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP975_RS09025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP975_RS09040	COG1799	cell septum assembly
CP975_RS09050	COG1496	oxidoreductase activity
CP975_RS09055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP975_RS09065	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP975_RS09070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP975_RS09080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP975_RS09085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP975_RS09090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CP975_RS09095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP975_RS09110	COG0275	rRNA processing
CP975_RS09120	COG0714	Associated with various cellular activities
CP975_RS09150	COG1129	ABC transporter
CP975_RS09160	COG1309	transcriptional regulator
CP975_RS09185	COG0352	thiamine-phosphate diphosphorylase activity
CP975_RS09195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP975_RS09200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP975_RS09200	COG2022	thiamine diphosphate biosynthetic process
CP975_RS09210	COG2022	thiamine diphosphate biosynthetic process
CP975_RS09215	COG2815	serine threonine protein kinase
CP975_RS09215	COG0515	serine threonine protein kinase
CP975_RS09220	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP975_RS09230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP975_RS09235	COG2193	ferroxidase activity
CP975_RS09240	COG0243	molybdopterin cofactor binding
CP975_RS09245	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP975_RS09270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP975_RS09275	COG0205	6-phosphofructokinase activity
CP975_RS09280	COG2197	response regulator
CP975_RS09285	COG4585	Histidine kinase
CP975_RS09310	COG1940	carbohydrate kinase activity
CP975_RS09320	COG0003	Pfam Anion-transporting ATPase
CP975_RS09340	COG0438	transferase activity, transferring glycosyl groups
CP975_RS09385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP975_RS09390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP975_RS09395	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP975_RS09400	COG0723	plastoquinol--plastocyanin reductase activity
CP975_RS09405	COG2010	Cytochrome c
CP975_RS09410	COG1845	cytochrome c oxidase, subunit III
CP975_RS09420	COG1376	ErfK ybiS ycfS ynhG family protein
CP975_RS09430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP975_RS09435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP975_RS09445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP975_RS09470	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP975_RS09475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP975_RS09480	COG2197	response regulator
CP975_RS09485	COG4585	Histidine kinase
CP975_RS09525	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP975_RS09530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP975_RS09530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP975_RS09545	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP975_RS09550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP975_RS09555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP975_RS09560	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP975_RS09600	COG1090	epimerase
CP975_RS09615	COG0321	lipoyl(octanoyl) transferase activity
CP975_RS09620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP975_RS09645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP975_RS09650	COG1120	ATPase activity
CP975_RS09655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS09700	COG0745	RESPONSE REGULATOR receiver
CP975_RS09715	COG4585	Histidine kinase
CP975_RS09720	COG2197	response regulator
CP975_RS09760	COG1309	transcriptional regulator
CP975_RS09790	COG3833	ABC-type maltose transport systems, permease component
CP975_RS09795	COG0366	Alpha amylase catalytic
CP975_RS09800	COG1609	Transcriptional regulator
CP975_RS09810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP975_RS09830	COG0174	glutamine synthetase
CP975_RS09835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP975_RS09840	COG4209	transmembrane transport
CP975_RS09845	COG0395	ABC-type sugar transport system, permease component
CP975_RS09855	COG1609	Transcriptional regulator
CP975_RS09860	COG2267	carboxylic ester hydrolase activity
CP975_RS09870	COG0531	amino acid
CP975_RS09880	COG2132	Multicopper oxidase
CP975_RS09885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP975_RS09885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP975_RS09890	COG2814	Major facilitator Superfamily
CP975_RS09905	COG0477	Major facilitator Superfamily
CP975_RS09910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP975_RS09930	COG1994	Peptidase M50
CP975_RS09995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP975_RS10000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS10005	COG1120	ATPase activity
CP975_RS10015	COG2837	iron assimilation
CP975_RS10020	COG0672	)-iron permease
CP975_RS10050	COG1834	amidinotransferase
CP975_RS10070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP975_RS10075	COG2814	Major facilitator Superfamily
CP975_RS10085	COG0438	transferase activity, transferring glycosyl groups
CP975_RS10090	COG3540	Alkaline phosphatase
CP975_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS10110	COG2259	Doxx family
CP975_RS10125	COG1846	Transcriptional regulator
CP975_RS10130	COG0778	Nitroreductase
CP975_RS10165	COG3903	Transcriptional regulator
CP975_RS10165	COG2197	response regulator
CP975_RS10215	COG1674	ftsk spoiiie
CP975_RS10235	COG3022	response to hydroperoxide
CP975_RS10240	COG0800	Aldolase
CP975_RS10255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP975_RS10260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP975_RS10270	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS10280	COG2030	dehydratase
CP975_RS10285	COG2197	response regulator
CP975_RS10295	COG0183	Belongs to the thiolase family
CP975_RS10320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP975_RS10345	COG0438	transferase activity, transferring glycosyl groups
CP975_RS10350	COG1309	transcriptional regulator
CP975_RS10370	COG1657	PFAM Prenyltransferase squalene oxidase
CP975_RS10385	COG3845	ABC transporter
CP975_RS10400	COG0183	Belongs to the thiolase family
CP975_RS10405	COG2124	cytochrome p450
CP975_RS10430	COG4122	O-methyltransferase activity
CP975_RS10470	COG0531	amino acid
CP975_RS10545	COG1358	cellular component organization or biogenesis
CP975_RS10590	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP975_RS10595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP975_RS10620	COG4585	Histidine kinase
CP975_RS10625	COG2197	response regulator
CP975_RS10640	COG0667	Aldo Keto reductase
CP975_RS10645	COG0789	Transcriptional regulator
CP975_RS10655	COG1741	Belongs to the pirin family
CP975_RS10670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP975_RS10675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS10680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS10700	COG1309	transcriptional regulator
CP975_RS10745	COG1764	response to oxidative stress
CP975_RS10750	COG2130	NADP-dependent
CP975_RS10790	COG0438	transferase activity, transferring glycosyl groups
CP975_RS10800	COG4981	capsule polysaccharide biosynthetic process
CP975_RS10840	COG0583	DNA-binding transcription factor activity
CP975_RS10850	COG2855	membrane
CP975_RS10865	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS10870	COG1404	Belongs to the peptidase S8 family
CP975_RS10875	COG1077	Cell shape determining protein MreB Mrl
CP975_RS10895	COG3585	molybdate ion transport
CP975_RS10900	COG1295	ribonuclease BN
CP975_RS10905	COG3290	protein histidine kinase activity
CP975_RS10910	COG4565	transcriptional regulatory protein
CP975_RS10925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP975_RS10930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP975_RS10935	COG4948	Mandelate Racemase Muconate Lactonizing
CP975_RS10945	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP975_RS10955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS10985	COG1070	Carbohydrate kinase
CP975_RS11000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP975_RS11005	COG0358	DNA primase activity
CP975_RS11015	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP975_RS11025	COG2949	membrane
CP975_RS11030	COG0243	molybdopterin cofactor binding
CP975_RS11050	COG2205	protein histidine kinase activity
CP975_RS11060	COG0789	Transcriptional regulator
CP975_RS11095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP975_RS11100	COG2146	nitrite reductase [NAD(P)H] activity
CP975_RS11100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP975_RS11110	COG1309	transcriptional regulator
CP975_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS11135	COG0395	ABC-type sugar transport system, permease component
CP975_RS11150	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CP975_RS11155	COG1846	Transcriptional regulator
CP975_RS11155	COG1940	carbohydrate kinase activity
CP975_RS11160	COG0574	Belongs to the PEP-utilizing enzyme family
CP975_RS11160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP975_RS11195	COG0477	Major facilitator Superfamily
CP975_RS11205	COG0667	Aldo Keto reductase
CP975_RS11220	COG0423	glycine-tRNA ligase activity
CP975_RS11225	COG3443	Belongs to the bacterial solute-binding protein 9 family
CP975_RS11225	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP975_RS11230	COG1121	(ABC) transporter
CP975_RS11235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP975_RS11245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP975_RS11250	COG1381	Involved in DNA repair and RecF pathway recombination
CP975_RS11300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP975_RS11305	COG0747	negative chemotaxis
CP975_RS11315	COG0444	Belongs to the ABC transporter superfamily
CP975_RS11320	COG4608	Belongs to the ABC transporter superfamily
CP975_RS11325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP975_RS11330	COG2197	response regulator
CP975_RS11335	COG4585	Histidine kinase
CP975_RS11340	COG2409	Drug exporters of the RND superfamily
CP975_RS11350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP975_RS11375	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP975_RS11405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP975_RS11415	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CP975_RS11415	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CP975_RS11425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP975_RS11430	COG1234	tRNA 3'-trailer cleavage
CP975_RS11435	COG0537	adenosine 5'-monophosphoramidase activity
CP975_RS11440	COG4946	Tricorn protease homolog
CP975_RS11440	COG0793	Belongs to the peptidase S41A family
CP975_RS11460	COG0484	heat shock protein binding
CP975_RS11465	COG1420	regulation of RNA biosynthetic process
CP975_RS11515	COG0481	GTPase activity
CP975_RS11520	COG0268	Binds directly to 16S ribosomal RNA
CP975_RS11545	COG2353	YceI-like domain
CP975_RS11550	COG1234	tRNA 3'-trailer cleavage
CP975_RS11555	COG1555	photosystem II stabilization
CP975_RS11560	COG1307	EDD domain protein, DegV family
CP975_RS11570	COG0495	leucyl-tRNA aminoacylation
CP975_RS11585	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP975_RS11610	COG0477	Major facilitator Superfamily
CP975_RS11625	COG0588	phosphoglycerate mutase activity
CP975_RS11630	COG0799	negative regulation of ribosome biogenesis
CP975_RS11640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP975_RS11650	COG0501	Belongs to the peptidase M48B family
CP975_RS11665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP975_RS11675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP975_RS11685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP975_RS11690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP975_RS11695	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP975_RS11705	COG1530	ribonuclease E activity
CP975_RS11735	COG0772	Belongs to the SEDS family
CP975_RS11740	COG0768	penicillin binding
CP975_RS11755	COG1077	Cell shape determining protein MreB Mrl
CP975_RS11760	COG0105	UTP biosynthetic process
CP975_RS11770	COG0285	dihydrofolate synthase activity
CP975_RS11780	COG4585	Histidine kinase
CP975_RS11790	COG0525	valine-tRNA ligase activity
CP975_RS11810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP975_RS11815	COG0740	serine-type endopeptidase activity
CP975_RS11820	COG0740	serine-type endopeptidase activity
CP975_RS11825	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP975_RS11845	COG3594	Acyltransferase
CP975_RS11855	COG1136	(ABC) transporter
CP975_RS11880	COG4552	Acetyltransferase involved in intracellular survival and related
CP975_RS11900	COG1113	amino acid transport
CP975_RS11910	COG1268	BioY protein
CP975_RS11915	COG1113	amino acid transport
CP975_RS11920	COG1113	amino acid transport
CP975_RS11925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP975_RS11930	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP975_RS11980	COG0583	DNA-binding transcription factor activity
CP975_RS12010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP975_RS12045	COG0668	transmembrane transport
CP975_RS12050	COG1940	carbohydrate kinase activity
CP975_RS12050	COG1846	Transcriptional regulator
CP975_RS12060	COG1175	transmembrane transport
CP975_RS12065	COG0395	ABC-type sugar transport system, permease component
CP975_RS12070	COG1486	melibiose metabolic process
CP975_RS12085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP975_RS12115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP975_RS12120	COG2346	COG2346, Truncated hemoglobins
CP975_RS12150	COG0629	single-stranded DNA binding
CP975_RS12155	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP975_RS12230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP975_RS12245	COG3962	Belongs to the TPP enzyme family
CP975_RS12250	COG3718	enzyme involved in inositol metabolism
CP975_RS12260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP975_RS12265	COG1082	Xylose isomerase domain protein TIM barrel
CP975_RS12290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP975_RS12305	COG0673	inositol 2-dehydrogenase activity
CP975_RS12320	COG1280	lysine exporter protein (LysE YggA)
CP975_RS12340	COG1472	Belongs to the glycosyl hydrolase 3 family
CP975_RS12370	COG0028	Belongs to the TPP enzyme family
CP975_RS12380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP975_RS12400	COG1946	Acyl-CoA thioesterase
CP975_RS12410	COG1309	transcriptional regulator
CP975_RS12415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP975_RS12425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP975_RS12430	COG1960	acyl-CoA dehydrogenase activity
CP975_RS12440	COG0076	glutamate decarboxylase activity
CP975_RS12445	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP975_RS12475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP975_RS12480	COG0589	response to stress
CP975_RS12490	COG4977	sequence-specific DNA binding
CP975_RS12495	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CP975_RS12520	COG0395	ABC-type sugar transport system, permease component
CP975_RS12535	COG0745	RESPONSE REGULATOR receiver
CP975_RS12560	COG0406	alpha-ribazole phosphatase activity
CP975_RS12610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP975_RS12635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP975_RS12640	COG0154	amidase activity
CP975_RS12655	COG0765	amino acid transport
CP975_RS12660	COG0765	amino acid transport
CP975_RS12665	COG1126	abc transporter atp-binding protein
CP975_RS12680	COG0586	Pfam SNARE associated Golgi protein
CP975_RS12685	COG3851	Histidine kinase
CP975_RS12690	COG2201	protein-glutamate methylesterase activity
CP975_RS12700	COG2197	response regulator
CP975_RS12710	COG3397	chitin binding
CP975_RS12730	COG2186	Transcriptional regulator
CP975_RS12785	COG0673	inositol 2-dehydrogenase activity
CP975_RS12790	COG4702	Belongs to the UPF0303 family
CP975_RS12820	COG0706	membrane insertase activity
CP975_RS12845	COG0270	DNA (cytosine-5-)-methyltransferase activity
CP975_RS12895	COG4977	sequence-specific DNA binding
CP975_RS12905	COG2733	membrane
CP975_RS12920	COG4555	ABC transporter
CP975_RS12935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP975_RS12935	COG4499	WXG100 protein secretion system (Wss), protein YukC
CP975_RS12980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP975_RS12990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP975_RS12995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP975_RS13000	COG1263	PTS System
CP975_RS13005	COG1263	PTS System
CP975_RS13010	COG1234	tRNA 3'-trailer cleavage
CP975_RS13040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS13055	COG1113	amino acid transport
CP975_RS13065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP975_RS13075	COG1335	isochorismatase
CP975_RS13110	COG0277	FAD linked oxidase domain protein
CP975_RS13135	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP975_RS13145	COG1174	glycine betaine transport
CP975_RS13150	COG0517	IMP dehydrogenase activity
CP975_RS13150	COG1125	glycine betaine transport
CP975_RS13155	COG1174	glycine betaine transport
CP975_RS13175	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP975_RS13210	COG2318	DinB family
CP975_RS13240	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP975_RS13250	COG2814	Major facilitator Superfamily
CP975_RS13255	COG0583	DNA-binding transcription factor activity
CP975_RS13260	COG1678	Uncharacterized ACR, COG1678
CP975_RS13265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP975_RS13270	COG0776	regulation of translation
CP975_RS13280	COG3973	AAA domain
CP975_RS13320	COG1846	Transcriptional regulator
CP975_RS13325	COG0697	spore germination
CP975_RS13330	COG2910	NAD(P)H-binding
CP975_RS13350	COG0583	DNA-binding transcription factor activity
CP975_RS13360	COG2027	D-alanyl-D-alanine carboxypeptidase
CP975_RS13370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP975_RS13375	COG0793	Belongs to the peptidase S41A family
CP975_RS13385	COG2884	Cell division ATP-binding protein ftsE
CP975_RS13400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP975_RS13405	COG0515	serine threonine protein kinase
CP975_RS13410	COG0515	serine threonine protein kinase
CP975_RS13420	COG3467	pyridoxamine 5'-phosphate
CP975_RS13430	COG1175	transmembrane transport
CP975_RS13435	COG0395	ABC-type sugar transport system, permease component
CP975_RS13445	COG0438	transferase activity, transferring glycosyl groups
CP975_RS13450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP975_RS13450	COG0463	Glycosyl transferase, family 2
CP975_RS13455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP975_RS13465	COG1215	transferase activity, transferring glycosyl groups
CP975_RS13485	COG1134	teichoic acid transport
CP975_RS13490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP975_RS13495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP975_RS13500	COG1215	transferase activity, transferring glycosyl groups
CP975_RS13520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP975_RS13525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP975_RS13565	COG1216	Glycosyl transferase, family 2
CP975_RS13580	COG2902	Dehydrogenase
CP975_RS13610	COG0653	protein targeting
CP975_RS13620	COG3214	Protein conserved in bacteria
CP975_RS13625	COG2197	response regulator
CP975_RS13630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP975_RS13640	COG0823	Involved in the tonB-independent uptake of proteins
CP975_RS13645	COG5000	phosphorelay sensor kinase activity
CP975_RS13645	COG5002	protein histidine kinase activity
CP975_RS13650	COG0745	RESPONSE REGULATOR receiver
CP975_RS13655	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP975_RS13675	COG0714	Associated with various cellular activities
CP975_RS13720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP975_RS13725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP975_RS13725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP975_RS13725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP975_RS13735	COG1482	cell wall glycoprotein biosynthetic process
CP975_RS13745	COG2835	tetraacyldisaccharide 4'-kinase activity
CP975_RS13750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP975_RS13755	COG1620	l-lactate permease
CP975_RS13795	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP975_RS13800	COG0778	Nitroreductase
CP975_RS13800	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP975_RS13825	COG1316	TRANSCRIPTIONal
CP975_RS13830	COG1316	TRANSCRIPTIONal
CP975_RS13845	COG1316	TRANSCRIPTIONal
CP975_RS13855	COG1316	TRANSCRIPTIONal
CP975_RS13885	COG1595	DNA-templated transcription, initiation
CP975_RS13890	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP975_RS13930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CP975_RS13945	COG2205	protein histidine kinase activity
CP975_RS13950	COG0745	RESPONSE REGULATOR receiver
CP975_RS13955	COG3104	oligopeptide transport
CP975_RS13985	COG1366	Belongs to the anti-sigma-factor antagonist family
CP975_RS13990	COG1191	sigma factor activity
CP975_RS14005	COG1228	amidohydrolase
CP975_RS14015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP975_RS14020	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP975_RS14045	COG3629	intracellular signal transduction
CP975_RS14045	COG3903	Transcriptional regulator
CP975_RS14055	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP975_RS14055	COG0515	serine threonine protein kinase
CP975_RS14080	COG4221	oxidoreductase activity
CP975_RS14095	COG2755	lipolytic protein G-D-S-L family
CP975_RS14100	COG0183	Belongs to the thiolase family
CP975_RS14125	COG2814	Major facilitator Superfamily
CP975_RS14135	COG1414	Transcriptional regulator
CP975_RS14145	COG1136	(ABC) transporter
CP975_RS14150	COG0577	efflux transmembrane transporter activity
CP975_RS14150	COG1136	(ABC) transporter
CP975_RS14155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP975_RS14165	COG1309	transcriptional regulator
CP975_RS14190	COG0148	phosphopyruvate hydratase activity
CP975_RS14200	COG1652	LysM domain
CP975_RS14205	COG2124	cytochrome p450
CP975_RS14220	COG0515	serine threonine protein kinase
CP975_RS14220	COG2815	serine threonine protein kinase
CP975_RS14265	COG0577	efflux transmembrane transporter activity
CP975_RS14270	COG1136	(ABC) transporter
CP975_RS14275	COG0477	Major facilitator Superfamily
CP975_RS14305	COG4585	Histidine kinase
CP975_RS14315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP975_RS14320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP975_RS14325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP975_RS14330	COG0193	aminoacyl-tRNA hydrolase activity
CP975_RS14335	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP975_RS14360	COG4106	trans-aconitate 2-methyltransferase activity
CP975_RS14365	COG1846	Transcriptional regulator
CP975_RS14370	COG2197	response regulator
CP975_RS14385	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP975_RS14425	COG0488	(ABC) transporter
CP975_RS14435	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP975_RS14440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP975_RS14445	COG3583	domain protein
CP975_RS14445	COG3584	3D domain protein
CP975_RS14450	COG0084	hydrolase, TatD family'
CP975_RS14480	COG0442	prolyl-tRNA aminoacylation
CP975_RS14495	COG1695	Transcriptional regulator
CP975_RS14510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP975_RS14515	COG1122	ATPase activity
CP975_RS14525	COG0310	cobalt ion transport
CP975_RS14535	COG2409	Drug exporters of the RND superfamily
CP975_RS14545	COG0793	Belongs to the peptidase S41A family
CP975_RS14545	COG4946	Tricorn protease homolog
CP975_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS14555	COG2267	carboxylic ester hydrolase activity
CP975_RS14560	COG2072	flavoprotein involved in K transport
CP975_RS14565	COG0789	Transcriptional regulator
CP975_RS14595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP975_RS14600	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP975_RS14600	COG0315	cyclic pyranopterin monophosphate synthase activity
CP975_RS14605	COG0315	cyclic pyranopterin monophosphate synthase activity
CP975_RS14615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP975_RS14620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP975_RS14625	COG2366	antibiotic biosynthetic process
CP975_RS14630	COG3263	regulation of cellular component size
CP975_RS14650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP975_RS14660	COG1970	mechanosensitive ion channel activity
CP975_RS14670	COG2223	nitrite transmembrane transporter activity
CP975_RS14680	COG3191	aminopeptidase activity
CP975_RS14700	COG0477	Major facilitator Superfamily
CP975_RS14715	COG1247	-acetyltransferase
CP975_RS14725	COG1846	Transcriptional regulator
CP975_RS14745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CP975_RS14750	COG1120	ATPase activity
CP975_RS14755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP975_RS14765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS14775	COG0477	Major facilitator Superfamily
CP975_RS14780	COG2382	esterase
CP975_RS14785	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS14795	COG1169	isochorismate synthase
CP975_RS14800	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP975_RS14805	COG1535	isochorismatase
CP975_RS14805	COG3433	isochorismatase activity
CP975_RS14815	COG1846	Transcriptional regulator
CP975_RS14820	COG1764	response to oxidative stress
CP975_RS14845	COG2124	cytochrome p450
CP975_RS14860	COG5640	endopeptidase activity
CP975_RS14865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP975_RS14895	COG1653	transport
CP975_RS14905	COG1686	Belongs to the peptidase S11 family
CP975_RS14955	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP975_RS15010	COG3903	Transcriptional regulator
CP975_RS15010	COG3629	intracellular signal transduction
CP975_RS15055	COG1024	Enoyl-CoA hydratase
CP975_RS15065	COG0515	serine threonine protein kinase
CP975_RS15065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP975_RS15075	COG1309	transcriptional regulator
CP975_RS15080	COG1960	acyl-CoA dehydrogenase activity
CP975_RS15095	COG0259	pyridoxamine-phosphate oxidase activity
CP975_RS15135	COG2072	flavoprotein involved in K transport
CP975_RS15145	COG1024	Enoyl-CoA hydratase
CP975_RS15175	COG1960	acyl-CoA dehydrogenase activity
CP975_RS15180	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS15195	COG1960	acyl-CoA dehydrogenase activity
CP975_RS15200	COG1960	acyl-CoA dehydrogenase activity
CP975_RS15205	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS15220	COG1366	Belongs to the anti-sigma-factor antagonist family
CP975_RS15285	COG4821	SIS domain
CP975_RS15295	COG2945	thiolester hydrolase activity
CP975_RS15295	COG0596	Alpha beta hydrolase
CP975_RS15300	COG0259	pyridoxamine-phosphate oxidase activity
CP975_RS15330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP975_RS15355	COG0277	FAD linked oxidase domain protein
CP975_RS15355	COG0247	lactate metabolic process
CP975_RS15390	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP975_RS15420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CP975_RS15455	COG0667	Aldo Keto reductase
CP975_RS15490	COG2252	PERMEase
CP975_RS15500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP975_RS15530	COG2814	Major facilitator Superfamily
CP975_RS15540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP975_RS15545	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP975_RS15550	COG1278	Cold shock
CP975_RS15565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS15570	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS15575	COG1120	ATPase activity
CP975_RS15580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP975_RS15605	COG1061	Type III restriction enzyme res subunit
CP975_RS15615	COG3973	AAA domain
CP975_RS15695	COG1737	Transcriptional regulator
CP975_RS15700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP975_RS15720	COG1122	ATPase activity
CP975_RS15755	COG1819	glycosyl
CP975_RS15790	COG0463	Glycosyl transferase, family 2
CP975_RS15815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP975_RS15860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP975_RS15925	COG2197	response regulator
CP975_RS15960	COG4552	Acetyltransferase involved in intracellular survival and related
CP975_RS15985	COG2226	methyltransferase
CP975_RS16025	COG3842	ATPase activity
CP975_RS16035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP975_RS16045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP975_RS16050	COG0215	cysteine-tRNA ligase activity
CP975_RS16055	COG3467	pyridoxamine 5'-phosphate
CP975_RS16060	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP975_RS16065	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP975_RS16070	COG1329	Transcriptional regulator
CP975_RS16090	COG5002	protein histidine kinase activity
CP975_RS16115	COG2814	Major facilitator Superfamily
CP975_RS16120	COG0588	phosphoglycerate mutase activity
CP975_RS16130	COG2188	Transcriptional regulator
CP975_RS16140	COG0438	transferase activity, transferring glycosyl groups
CP975_RS16185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP975_RS16200	COG1733	regulation of RNA biosynthetic process
CP975_RS16205	COG2084	Dehydrogenase
CP975_RS16215	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP975_RS16220	COG0768	penicillin binding
CP975_RS16260	COG2186	Transcriptional regulator
CP975_RS16270	COG2186	Transcriptional regulator
CP975_RS16280	COG4552	Acetyltransferase involved in intracellular survival and related
CP975_RS16295	COG1490	D-aminoacyl-tRNA deacylase activity
CP975_RS16310	COG3485	protocatechuate 3,4-dioxygenase
CP975_RS16335	COG2897	thiosulfate sulfurtransferase activity
CP975_RS16360	COG0745	RESPONSE REGULATOR receiver
CP975_RS16365	COG1609	Transcriptional regulator
CP975_RS16370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP975_RS16375	COG0745	RESPONSE REGULATOR receiver
CP975_RS16380	COG2205	protein histidine kinase activity
CP975_RS16395	COG0737	Belongs to the 5'-nucleotidase family
CP975_RS16405	COG0456	acetyltransferase
CP975_RS16415	COG1116	anion transmembrane transporter activity
CP975_RS16425	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CP975_RS16435	COG0406	alpha-ribazole phosphatase activity
CP975_RS16435	COG0494	nUDIX hydrolase
CP975_RS16455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP975_RS16460	COG0306	phosphate transporter
CP975_RS16470	COG1937	Protein conserved in bacteria
CP975_RS16485	COG0277	FAD linked oxidase domain protein
CP975_RS16490	COG0671	phosphoesterase, PA-phosphatase related
CP975_RS16495	COG1196	nuclear chromosome segregation
CP975_RS16495	COG0739	heme binding
CP975_RS16495	COG0741	lytic transglycosylase activity
CP975_RS16600	COG1252	NADH dehydrogenase
CP975_RS16630	COG0579	oxidoreductase
CP975_RS16635	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP975_RS16645	COG0667	Aldo Keto reductase
CP975_RS16665	COG0477	Major facilitator Superfamily
CP975_RS16720	COG0785	Cytochrome C biogenesis protein
CP975_RS16725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP975_RS16725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP975_RS16735	COG1643	Atp-dependent helicase
CP975_RS16770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP975_RS16805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP975_RS16810	COG0047	phosphoribosylformylglycinamidine synthase activity
CP975_RS16815	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP975_RS16850	COG2197	response regulator
CP975_RS16860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP975_RS16875	COG0151	Belongs to the GarS family
CP975_RS16930	COG0488	(ABC) transporter
CP975_RS16950	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP975_RS16980	COG1191	sigma factor activity
CP975_RS16985	COG1191	sigma factor activity
CP975_RS17005	COG0477	Major facilitator Superfamily
CP975_RS17020	COG0477	Major facilitator Superfamily
CP975_RS17025	COG0745	RESPONSE REGULATOR receiver
CP975_RS17040	COG2329	Antibiotic biosynthesis monooxygenase
CP975_RS17065	COG0784	Response regulator, receiver
CP975_RS17070	COG1309	transcriptional regulator
CP975_RS17075	COG2814	Major facilitator Superfamily
CP975_RS17080	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS17085	COG1595	DNA-templated transcription, initiation
CP975_RS17125	COG0494	nUDIX hydrolase
CP975_RS17175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP975_RS17190	COG0653	protein targeting
CP975_RS17210	COG0006	proline dipeptidase activity
CP975_RS17215	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS17220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP975_RS17240	COG1999	signal sequence binding
CP975_RS17255	COG2837	iron assimilation
CP975_RS17265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP975_RS17270	COG0561	phosphatase activity
CP975_RS17310	COG0789	Transcriptional regulator
CP975_RS17315	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP975_RS17325	COG0561	phosphatase activity
CP975_RS17330	COG0739	heme binding
CP975_RS17330	COG1196	nuclear chromosome segregation
CP975_RS17330	COG0741	lytic transglycosylase activity
CP975_RS17340	COG4988	ABC transporter
CP975_RS17345	COG1294	oxidase, subunit
CP975_RS17350	COG1271	oxidase subunit
CP975_RS17355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP975_RS17360	COG1609	Transcriptional regulator
CP975_RS17375	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP975_RS17400	COG0662	Cupin 2, conserved barrel domain protein
CP975_RS17405	COG1950	PFAM Membrane protein of
CP975_RS17410	COG0626	cystathionine gamma-synthase activity
CP975_RS17440	COG2814	Major facilitator Superfamily
CP975_RS17450	COG0456	acetyltransferase
CP975_RS17485	COG0305	Participates in initiation and elongation during chromosome replication
CP975_RS17495	COG0359	binds to the 23S rRNA
CP975_RS17500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP975_RS17505	COG0629	single-stranded DNA binding
CP975_RS17510	COG0360	Binds together with S18 to 16S ribosomal RNA
CP975_RS17535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP975_RS17560	COG0617	tRNA 3'-terminal CCA addition
CP975_RS17580	COG1595	DNA-templated transcription, initiation
CP975_RS17590	COG0492	ferredoxin-NADP+ reductase activity
CP975_RS17595	COG3118	belongs to the thioredoxin family
CP975_RS17610	COG1192	Involved in chromosome partitioning
CP975_RS17615	COG0357	Ribosomal RNA small subunit methyltransferase G
CP975_RS17625	COG0706	membrane insertase activity
CP975_RS17630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP975_RS17635	COG0594	ribonuclease P activity
CP975_RS17640	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CP975_RS17645	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CP975_RS17655	COG0592	DNA-directed DNA polymerase activity
CP975_RS17660	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP975_RS17665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP975_RS17670	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP975_RS17680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP975_RS17710	COG0515	serine threonine protein kinase
CP975_RS17740	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS17760	COG0488	(ABC) transporter
CP975_RS17765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CP975_RS17775	COG2226	methyltransferase
CP975_RS17780	COG3903	Transcriptional regulator
CP975_RS17780	COG3629	intracellular signal transduction
CP975_RS17805	COG0705	Rhomboid family
CP975_RS17820	COG3764	Sortase (surface protein transpeptidase)
CP975_RS17835	COG3764	Sortase (surface protein transpeptidase)
CP975_RS17840	COG3764	Sortase (surface protein transpeptidase)
CP975_RS17845	COG0515	serine threonine protein kinase
CP975_RS17870	COG1716	ATPase activity
CP975_RS17875	COG1716	ATPase activity
CP975_RS17900	COG1960	acyl-CoA dehydrogenase activity
CP975_RS17905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP975_RS17910	COG2151	metal-sulfur cluster biosynthetic enzyme
CP975_RS17915	COG3396	Phenylacetate-CoA oxygenase
CP975_RS17920	COG3460	Phenylacetate-CoA oxygenase
CP975_RS17925	COG3396	Phenylacetate-CoA oxygenase
CP975_RS17950	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP975_RS17955	COG1309	transcriptional regulator
CP975_RS17960	COG1522	sequence-specific DNA binding
CP975_RS17985	COG0303	'Molybdopterin
CP975_RS17990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP975_RS17995	COG3321	synthase
CP975_RS17995	COG0604	alcohol dehydrogenase
CP975_RS17995	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS18005	COG0515	serine threonine protein kinase
CP975_RS18010	COG0515	serine threonine protein kinase
CP975_RS18030	COG0022	dehydrogenase e1 component
CP975_RS18035	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP975_RS18045	COG2186	Transcriptional regulator
CP975_RS18050	COG2271	Major facilitator Superfamily
CP975_RS18075	COG1362	aminopeptidase activity
CP975_RS18080	COG1960	acyl-CoA dehydrogenase activity
CP975_RS18095	COG0584	glycerophosphoryl diester phosphodiesterase
CP975_RS18100	COG1741	Belongs to the pirin family
CP975_RS18115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP975_RS18135	COG1309	transcriptional regulator
CP975_RS18145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP975_RS18165	COG0583	DNA-binding transcription factor activity
CP975_RS18175	COG1289	transmembrane transporter activity
CP975_RS18220	COG0583	DNA-binding transcription factor activity
CP975_RS18260	COG1215	transferase activity, transferring glycosyl groups
CP975_RS18265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CP975_RS18310	COG2186	Transcriptional regulator
CP975_RS18365	COG0717	Belongs to the dCTP deaminase family
CP975_RS18405	COG2181	nitrate reductase activity
CP975_RS18405	COG0247	lactate metabolic process
CP975_RS18410	COG0443	Heat shock 70 kDa protein
CP975_RS18415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP975_RS18420	COG0484	heat shock protein binding
CP975_RS18425	COG0789	Transcriptional regulator
CP975_RS18450	COG0542	response to heat
CP975_RS18475	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP975_RS18490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP975_RS18495	COG0191	fructose-bisphosphate aldolase activity
CP975_RS18520	COG3844	kynureninase activity
CP975_RS18535	COG2197	response regulator
CP975_RS18540	COG2124	cytochrome p450
CP975_RS18545	COG3559	Exporter of polyketide antibiotics
CP975_RS18550	COG1131	(ABC) transporter
CP975_RS18565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP975_RS18590	COG0693	protein deglycase activity
CP975_RS18625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP975_RS18630	COG1802	Transcriptional regulator
CP975_RS18635	COG0463	Glycosyl transferase, family 2
CP975_RS18650	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP975_RS18655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP975_RS18675	COG1595	DNA-templated transcription, initiation
CP975_RS18695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CP975_RS18750	COG0438	transferase activity, transferring glycosyl groups
CP975_RS18770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP975_RS18775	COG0438	transferase activity, transferring glycosyl groups
CP975_RS18830	COG4942	peptidase
CP975_RS18895	COG2319	Wd-40 repeat
CP975_RS18895	COG4249	Peptidase C14 caspase catalytic subunit p20
CP975_RS18975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP975_RS18990	COG0017	Asparaginyl-tRNA synthetase
CP975_RS19070	COG1609	Transcriptional regulator
CP975_RS19085	COG1196	nuclear chromosome segregation
CP975_RS19110	COG2188	Transcriptional regulator
CP975_RS19140	COG1408	metallophosphoesterase
CP975_RS19150	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CP975_RS19165	COG0003	Pfam Anion-transporting ATPase
CP975_RS19190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP975_RS19220	COG2267	carboxylic ester hydrolase activity
CP975_RS19230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP975_RS19235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP975_RS19300	COG1111	helicase
CP975_RS19300	COG1205	dead DEAH box helicase
CP975_RS19305	COG1366	Belongs to the anti-sigma-factor antagonist family
CP975_RS19310	COG2172	sigma factor antagonist activity
CP975_RS19315	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CP975_RS19325	COG2890	protein-(glutamine-N5) methyltransferase activity
CP975_RS19335	COG1754	DNA topoisomerase type I activity
CP975_RS19335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP975_RS19340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP975_RS19345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CP975_RS19385	COG2197	response regulator
CP975_RS19405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS19410	COG1595	DNA-templated transcription, initiation
CP975_RS19420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP975_RS19420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP975_RS19425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP975_RS19425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP975_RS19435	COG1136	(ABC) transporter
CP975_RS19450	COG2205	protein histidine kinase activity
CP975_RS19455	COG0745	RESPONSE REGULATOR receiver
CP975_RS19470	COG0577	efflux transmembrane transporter activity
CP975_RS19470	COG1136	(ABC) transporter
CP975_RS19475	COG0577	efflux transmembrane transporter activity
CP975_RS19475	COG1136	(ABC) transporter
CP975_RS19480	COG1289	transmembrane transporter activity
CP975_RS19490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP975_RS19495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP975_RS19500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP975_RS19505	COG0254	rRNA binding
CP975_RS19515	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP975_RS19535	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS19540	COG2318	DinB family
CP975_RS19560	COG0789	Transcriptional regulator
CP975_RS19575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP975_RS19580	COG2027	D-alanyl-D-alanine carboxypeptidase
CP975_RS19590	COG0037	tRNA processing
CP975_RS19605	COG0302	gtp cyclohydrolase
CP975_RS19615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CP975_RS19620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP975_RS19650	COG1174	glycine betaine transport
CP975_RS19655	COG1174	glycine betaine transport
CP975_RS19660	COG1732	Glycine betaine
CP975_RS19680	COG0649	NAD binding
CP975_RS19695	COG2197	response regulator
CP975_RS19710	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CP975_RS19720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP975_RS19725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP975_RS19735	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP975_RS19755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP975_RS19785	COG0739	heme binding
CP975_RS19795	COG0477	Major facilitator Superfamily
CP975_RS19800	COG0346	lactoylglutathione lyase activity
CP975_RS19805	COG2205	protein histidine kinase activity
CP975_RS19810	COG0745	RESPONSE REGULATOR receiver
CP975_RS19820	COG1595	DNA-templated transcription, initiation
CP975_RS19825	COG1194	a g-specific adenine glycosylase
CP975_RS19835	COG2197	response regulator
CP975_RS19850	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP975_RS19870	COG0248	Ppx GppA phosphatase
CP975_RS19875	COG1082	Xylose isomerase domain protein TIM barrel
CP975_RS19880	COG1309	transcriptional regulator
CP975_RS19885	COG0129	dihydroxy-acid dehydratase activity
CP975_RS19890	COG4991	sh3 domain protein
CP975_RS19905	COG0842	Transport permease protein
CP975_RS19905	COG1129	ABC transporter
CP975_RS19915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP975_RS19920	COG0180	Tryptophanyl-tRNA synthetase
CP975_RS19945	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP975_RS19995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP975_RS20000	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP975_RS20005	COG0181	hydroxymethylbilane synthase activity
CP975_RS20010	COG1648	precorrin-2 dehydrogenase activity
CP975_RS20010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP975_RS20015	COG0113	porphobilinogen synthase activity
CP975_RS20020	COG3321	synthase
CP975_RS20020	COG0604	alcohol dehydrogenase
CP975_RS20040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP975_RS20045	COG0018	arginyl-trna synthetase
CP975_RS20050	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CP975_RS20080	COG1690	Belongs to the RtcB family
CP975_RS20095	COG1742	UPF0060 membrane protein
CP975_RS20110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP975_RS20115	COG0406	alpha-ribazole phosphatase activity
CP975_RS20130	COG0785	Cytochrome C biogenesis protein
CP975_RS20135	COG1333	cytochrome c biogenesis protein
CP975_RS20140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP975_RS20155	COG0697	spore germination
CP975_RS20170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP975_RS20180	COG0163	prenyltransferase activity
CP975_RS20190	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP975_RS20200	COG1301	dicarboxylic acid transport
CP975_RS20205	COG1309	transcriptional regulator
CP975_RS20265	COG1022	Amp-dependent synthetase and ligase
CP975_RS20285	COG1278	Cold shock
CP975_RS20290	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP975_RS20310	COG1674	ftsk spoiiie
CP975_RS20360	COG5640	endopeptidase activity
CP975_RS20375	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CP975_RS20420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP975_RS20430	COG2226	methyltransferase
CP975_RS20460	COG0791	NLP P60 protein
CP975_RS20460	COG1388	LysM domain
CP975_RS20460	COG3103	Sh3 type 3 domain protein
CP975_RS20470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP975_RS20475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP975_RS20480	COG0649	NAD binding
CP975_RS20490	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP975_RS20495	COG1034	ATP synthesis coupled electron transport
CP975_RS20500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP975_RS20505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP975_RS20510	COG0839	Belongs to the complex I subunit 6 family
CP975_RS20515	COG0713	ATP synthesis coupled electron transport
CP975_RS20520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP975_RS20530	COG1007	ATP synthesis coupled electron transport
CP975_RS20545	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP975_RS20550	COG0561	phosphatase activity
CP975_RS20555	COG2936	dipeptidyl-peptidase activity
CP975_RS20560	COG0142	geranyltranstransferase activity
CP975_RS20610	COG0702	epimerase
CP975_RS20615	COG1733	regulation of RNA biosynthetic process
CP975_RS20620	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP975_RS20625	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP975_RS20625	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP975_RS20645	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP975_RS20650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP975_RS20655	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP975_RS20660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP975_RS20665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP975_RS20670	COG0839	Belongs to the complex I subunit 6 family
CP975_RS20675	COG0713	ATP synthesis coupled electron transport
CP975_RS20680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP975_RS20690	COG1007	ATP synthesis coupled electron transport
CP975_RS20695	COG0501	Belongs to the peptidase M48B family
CP975_RS20700	COG3304	Inner membrane component domain
CP975_RS20725	COG1666	GTP binding
CP975_RS20765	COG2188	Transcriptional regulator
CP975_RS20805	COG0702	epimerase
CP975_RS20810	COG0402	S-adenosylhomocysteine deaminase activity
CP975_RS20825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP975_RS20830	COG2030	dehydratase
CP975_RS20845	COG0477	Major facilitator Superfamily
CP975_RS20850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP975_RS20855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP975_RS20860	COG0436	Aminotransferase
CP975_RS20870	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP975_RS20880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CP975_RS20885	COG0081	regulation of translation
CP975_RS20900	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CP975_RS20905	COG0222	ribosome binding
CP975_RS20915	COG0085	RNA polymerase activity
CP975_RS20920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP975_RS20925	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP975_RS20930	COG0049	tRNA binding
CP975_RS20935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP975_RS20945	COG0051	transcription antitermination factor activity, RNA binding
CP975_RS20950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP975_RS20955	COG0088	Forms part of the polypeptide exit tunnel
CP975_RS20960	COG0089	rRNA binding
CP975_RS20965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP975_RS20970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP975_RS20975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP975_RS20980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP975_RS20985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP975_RS20990	COG0255	Belongs to the universal ribosomal protein uL29 family
CP975_RS20995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP975_RS21000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP975_RS21005	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP975_RS21010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP975_RS21015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP975_RS21025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP975_RS21030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP975_RS21035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP975_RS21040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP975_RS21045	COG1841	ribosomal large subunit assembly
CP975_RS21050	COG0200	Binds to the 23S rRNA
CP975_RS21060	COG0563	adenylate kinase activity
CP975_RS21070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP975_RS21075	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP975_RS21080	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP975_RS21085	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP975_RS21090	COG0202	RNA polymerase activity
CP975_RS21095	COG0203	ribosomal protein L17
CP975_RS21100	COG0101	tRNA pseudouridine synthase activity
CP975_RS21115	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP975_RS21120	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP975_RS21125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP975_RS21135	COG1072	(Pantothenic acid kinase))
CP975_RS21140	COG0736	holo-[acyl-carrier-protein] synthase activity
CP975_RS21150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP975_RS21160	COG0802	atpase or kinase
CP975_RS21185	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP975_RS21215	COG0726	polysaccharide deacetylase
CP975_RS21220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP975_RS21225	COG0459	protein refolding
CP975_RS21230	COG4221	oxidoreductase activity
CP975_RS21235	COG0583	DNA-binding transcription factor activity
CP975_RS21245	COG2197	response regulator
CP975_RS21250	COG1595	DNA-templated transcription, initiation
CP975_RS21260	COG0516	GMP reductase activity
CP975_RS21270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP975_RS21295	COG0515	serine threonine protein kinase
CP975_RS21300	COG0515	serine threonine protein kinase
CP975_RS21305	COG0515	serine threonine protein kinase
CP975_RS21310	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS21340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP975_RS21340	COG0519	Catalyzes the synthesis of GMP from XMP
CP975_RS21380	COG2197	response regulator
CP975_RS21420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP975_RS21420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP975_RS21435	COG0714	Associated with various cellular activities
CP975_RS21440	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CP975_RS21445	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP975_RS21455	COG0045	succinate-CoA ligase (ADP-forming) activity
CP975_RS21485	COG0138	bifunctional purine biosynthesis protein purh
CP975_RS21495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP975_RS21505	COG4585	Histidine kinase
CP975_RS21510	COG2197	response regulator
CP975_RS21520	COG0039	L-malate dehydrogenase activity
CP975_RS21525	COG0477	Major facilitator Superfamily
CP975_RS21535	COG1476	TRANSCRIPTIONal
CP975_RS21545	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS21555	COG0517	IMP dehydrogenase activity
CP975_RS21555	COG4175	Glycine betaine
CP975_RS21570	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CP975_RS21575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS21580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS21585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP975_RS21600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP975_RS21605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP975_RS21610	COG0180	Tryptophanyl-tRNA synthetase
CP975_RS21635	COG0671	phosphoesterase, PA-phosphatase related
CP975_RS21650	COG1295	ribonuclease BN
CP975_RS21655	COG1686	Belongs to the peptidase S11 family
CP975_RS21665	COG1408	metallophosphoesterase
CP975_RS21690	COG1053	succinate dehydrogenase
CP975_RS21700	COG2009	succinate dehydrogenase
CP975_RS21710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP975_RS21740	COG1595	DNA-templated transcription, initiation
CP975_RS21755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP975_RS21760	COG1595	DNA-templated transcription, initiation
CP975_RS21775	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP975_RS21775	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP975_RS21785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP975_RS21795	COG1216	Glycosyl transferase, family 2
CP975_RS21810	COG2089	acid synthase
CP975_RS21840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP975_RS21840	COG1473	amidohydrolase
CP975_RS21845	COG1744	ABC transporter substrate-binding protein PnrA-like
CP975_RS21850	COG1744	ABC transporter substrate-binding protein PnrA-like
CP975_RS21855	COG3845	ABC transporter
CP975_RS21865	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP975_RS21900	COG2814	Major facilitator Superfamily
CP975_RS21905	COG0583	DNA-binding transcription factor activity
CP975_RS21915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP975_RS21940	COG2205	protein histidine kinase activity
CP975_RS21945	COG0745	RESPONSE REGULATOR receiver
CP975_RS21950	COG1595	DNA-templated transcription, initiation
CP975_RS21965	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS21970	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS21975	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CP975_RS21990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP975_RS22030	COG4770	biotin carboxylase activity
CP975_RS22040	COG0424	maF-like protein
CP975_RS22050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP975_RS22060	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP975_RS22065	COG1024	Enoyl-CoA hydratase
CP975_RS22075	COG2986	histidine ammonia-lyase
CP975_RS22100	COG1404	Belongs to the peptidase S8 family
CP975_RS22105	COG2267	carboxylic ester hydrolase activity
CP975_RS22115	COG1064	alcohol dehydrogenase
CP975_RS22130	COG0740	serine-type endopeptidase activity
CP975_RS22135	COG0740	serine-type endopeptidase activity
CP975_RS22145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP975_RS22165	COG1595	DNA-templated transcription, initiation
CP975_RS22170	COG2255	four-way junction helicase activity
CP975_RS22175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP975_RS22190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP975_RS22200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP975_RS22220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS22225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS22245	COG3629	intracellular signal transduction
CP975_RS22245	COG3903	Transcriptional regulator
CP975_RS22250	COG1331	Highly conserved protein containing a thioredoxin domain
CP975_RS22260	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP975_RS22285	COG0071	Belongs to the small heat shock protein (HSP20) family
CP975_RS22300	COG1278	Cold shock
CP975_RS22305	COG0513	Belongs to the DEAD box helicase family
CP975_RS22320	COG2813	Specifically methylates the guanine in position
CP975_RS22325	COG2318	DinB family
CP975_RS22330	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP975_RS22345	COG1414	Transcriptional regulator
CP975_RS22350	COG0251	oxidation-reduction process
CP975_RS22355	COG2610	gluconate transmembrane transporter activity
CP975_RS22425	COG2885	chlorophyll binding
CP975_RS22435	COG1733	regulation of RNA biosynthetic process
CP975_RS22450	COG0667	Aldo Keto reductase
CP975_RS22455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP975_RS22460	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP975_RS22475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS22480	COG0450	alkyl hydroperoxide reductase
CP975_RS22495	COG1136	(ABC) transporter
CP975_RS22505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP975_RS22515	COG2264	protein methyltransferase activity
CP975_RS22525	COG0114	fumarate hydratase activity
CP975_RS22535	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP975_RS22535	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP975_RS22560	COG0778	Nitroreductase
CP975_RS22565	COG1722	exodeoxyribonuclease VII activity
CP975_RS22570	COG1570	exodeoxyribonuclease VII activity
CP975_RS22580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP975_RS22595	COG0012	GTP binding
CP975_RS22605	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CP975_RS22625	COG1278	Cold shock
CP975_RS22630	COG0513	Belongs to the DEAD box helicase family
CP975_RS22645	COG0475	glutathione-regulated potassium exporter activity
CP975_RS22655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS22665	COG3629	intracellular signal transduction
CP975_RS22665	COG3903	Transcriptional regulator
CP975_RS22670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CP975_RS22695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS22730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS22735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS22740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS22765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS22775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS22775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS22795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP975_RS22805	COG3629	intracellular signal transduction
CP975_RS22830	COG2271	Major facilitator Superfamily
CP975_RS22840	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP975_RS22845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP975_RS22850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS22855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS22860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP975_RS22885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP975_RS22895	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS22925	COG0477	Major facilitator Superfamily
CP975_RS22935	COG1597	lipid kinase activity
CP975_RS23020	COG1842	Phage shock protein A
CP975_RS23045	COG2186	Transcriptional regulator
CP975_RS23050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP975_RS23055	COG1053	succinate dehydrogenase
CP975_RS23075	COG1217	gtp-binding protein TYPA
CP975_RS23085	COG0601	transmembrane transport
CP975_RS23090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP975_RS23095	COG0444	Belongs to the ABC transporter superfamily
CP975_RS23100	COG4608	Belongs to the ABC transporter superfamily
CP975_RS23105	COG1595	DNA-templated transcription, initiation
CP975_RS23115	COG4608	Belongs to the ABC transporter superfamily
CP975_RS23120	COG0444	Belongs to the ABC transporter superfamily
CP975_RS23125	COG0601	transmembrane transport
CP975_RS23130	COG4166	transmembrane transport
CP975_RS23135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP975_RS23145	COG0601	transmembrane transport
CP975_RS23150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP975_RS23155	COG0444	Belongs to the ABC transporter superfamily
CP975_RS23160	COG4608	Belongs to the ABC transporter superfamily
CP975_RS23175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP975_RS23190	COG1131	(ABC) transporter
CP975_RS23195	COG0842	Transport permease protein
CP975_RS23200	COG4585	Histidine kinase
CP975_RS23205	COG2197	response regulator
CP975_RS23245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP975_RS23250	COG1611	Belongs to the LOG family
CP975_RS23255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP975_RS23265	COG2818	Glycosylase
CP975_RS23270	COG1024	Enoyl-CoA hydratase
CP975_RS23285	COG1595	DNA-templated transcription, initiation
CP975_RS23295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP975_RS23300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP975_RS23335	COG0598	Magnesium transport protein CorA
CP975_RS23355	COG2095	MarC family integral membrane protein
CP975_RS23360	COG1432	Conserved Protein
CP975_RS23370	COG0513	Belongs to the DEAD box helicase family
CP975_RS23400	COG0596	Alpha beta hydrolase
CP975_RS23415	COG1609	Transcriptional regulator
CP975_RS23425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP975_RS23435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP975_RS23515	COG0210	DNA helicase
CP975_RS23575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP975_RS23625	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP975_RS23635	COG1615	UPF0182 protein
CP975_RS23660	COG0753	catalase activity
CP975_RS23670	COG0483	inositol monophosphate 1-phosphatase activity
CP975_RS23680	COG2076	Multidrug Resistance protein
CP975_RS23690	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP975_RS23700	COG2135	peptidase activity
CP975_RS23710	COG1595	DNA-templated transcription, initiation
CP975_RS23715	COG5662	AntiSigma factor
CP975_RS23720	COG2199	diguanylate cyclase activity
CP975_RS23720	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP975_RS23735	COG0242	peptide deformylase activity
CP975_RS23745	COG2124	cytochrome p450
CP975_RS23780	COG1966	Carbon starvation protein
CP975_RS23785	COG2188	Transcriptional regulator
CP975_RS23790	COG2182	Extracellular solute-binding protein
CP975_RS23795	COG1175	transmembrane transport
CP975_RS23800	COG0395	ABC-type sugar transport system, permease component
CP975_RS23805	COG1472	Belongs to the glycosyl hydrolase 3 family
CP975_RS23810	COG0363	glucosamine-6-phosphate deaminase activity
CP975_RS23815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP975_RS23820	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS23825	COG1309	transcriptional regulator
CP975_RS23840	COG1597	lipid kinase activity
CP975_RS23855	COG2172	sigma factor antagonist activity
CP975_RS23885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP975_RS23890	COG0142	geranyltranstransferase activity
CP975_RS23915	COG1011	Hydrolase
CP975_RS23920	COG1595	DNA-templated transcription, initiation
CP975_RS23940	COG2197	response regulator
CP975_RS24010	COG2226	methyltransferase
CP975_RS24045	COG0582	viral genome integration into host DNA
CP975_RS24065	COG4106	trans-aconitate 2-methyltransferase activity
CP975_RS24070	COG1126	abc transporter atp-binding protein
CP975_RS24075	COG0765	amino acid transport
CP975_RS24085	COG0281	malic enzyme
CP975_RS24090	COG0604	alcohol dehydrogenase
CP975_RS24125	COG0567	Dehydrogenase, E1 component
CP975_RS24125	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP975_RS24130	COG2205	protein histidine kinase activity
CP975_RS24135	COG0745	RESPONSE REGULATOR receiver
CP975_RS24155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP975_RS24175	COG5002	protein histidine kinase activity
CP975_RS24235	COG0772	Belongs to the SEDS family
CP975_RS24245	COG2205	protein histidine kinase activity
CP975_RS24280	COG3285	dna ligase
CP975_RS24280	COG1793	dna ligase
CP975_RS24285	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP975_RS24300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS24315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS24345	COG1136	(ABC) transporter
CP975_RS24345	COG0577	efflux transmembrane transporter activity
CP975_RS24350	COG4585	Histidine kinase
CP975_RS24360	COG0583	DNA-binding transcription factor activity
CP975_RS24385	COG0018	arginyl-trna synthetase
CP975_RS24390	COG0019	diaminopimelate decarboxylase activity
CP975_RS24395	COG0460	homoserine dehydrogenase
CP975_RS24400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP975_RS24405	COG0083	homoserine kinase activity
CP975_RS24420	COG0254	rRNA binding
CP975_RS24425	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP975_RS24430	COG2890	protein-(glutamine-N5) methyltransferase activity
CP975_RS24440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP975_RS24445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP975_RS24465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP975_RS24470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP975_RS24475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP975_RS24480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP975_RS24485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP975_RS24490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP975_RS24495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP975_RS24510	COG2197	response regulator
CP975_RS24515	COG4585	Histidine kinase
CP975_RS24540	COG1309	transcriptional regulator
CP975_RS24545	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP975_RS24560	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP975_RS24620	COG0183	Belongs to the thiolase family
CP975_RS24640	COG2205	protein histidine kinase activity
CP975_RS24685	COG1309	transcriptional regulator
CP975_RS24715	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP975_RS24715	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP975_RS24720	COG2205	protein histidine kinase activity
CP975_RS24725	COG0745	RESPONSE REGULATOR receiver
CP975_RS24730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP975_RS24735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP975_RS24770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP975_RS24775	COG0857	belongs to the CobB CobQ family
CP975_RS24775	COG0280	phosphate acetyltransferase
CP975_RS24780	COG0205	6-phosphofructokinase activity
CP975_RS24800	COG0395	ABC-type sugar transport system, permease component
CP975_RS24805	COG1175	transmembrane transport
CP975_RS24815	COG4565	transcriptional regulatory protein
CP975_RS24820	COG3290	protein histidine kinase activity
CP975_RS24825	COG1301	dicarboxylic acid transport
CP975_RS24835	COG0477	Major facilitator Superfamily
CP975_RS24850	COG0789	Transcriptional regulator
CP975_RS24860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP975_RS24875	COG3118	belongs to the thioredoxin family
CP975_RS24875	COG0492	ferredoxin-NADP+ reductase activity
CP975_RS24885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP975_RS24900	COG0366	Alpha amylase catalytic
CP975_RS24910	COG0058	SHG alpha-glucan phosphorylase activity
CP975_RS24925	COG1132	(ABC) transporter
CP975_RS24930	COG1132	(ABC) transporter
CP975_RS24945	COG0583	DNA-binding transcription factor activity
CP975_RS24990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP975_RS25020	COG1760	l-serine dehydratase
CP975_RS25025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP975_RS25030	COG0509	glycine decarboxylation via glycine cleavage system
CP975_RS25035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP975_RS25055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP975_RS25065	COG0601	transmembrane transport
CP975_RS25070	COG0444	Belongs to the ABC transporter superfamily
CP975_RS25075	COG4608	Belongs to the ABC transporter superfamily
CP975_RS25080	COG2860	membrane
CP975_RS25090	COG2378	regulation of single-species biofilm formation
CP975_RS25120	COG0482	sulfurtransferase activity
CP975_RS25160	COG4221	oxidoreductase activity
CP975_RS25170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP975_RS25180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP975_RS25185	COG0154	amidase activity
CP975_RS25195	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP975_RS25205	COG3511	phospholipase C
CP975_RS25210	COG2409	Drug exporters of the RND superfamily
CP975_RS25215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP975_RS25230	COG2197	response regulator
CP975_RS25245	COG0667	Aldo Keto reductase
CP975_RS25270	COG0440	acetolactate synthase activity
CP975_RS25275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP975_RS25280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP975_RS25285	COG0477	Major facilitator Superfamily
CP975_RS25300	COG0506	proline dehydrogenase activity
CP975_RS25305	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS25320	COG1902	pentaerythritol trinitrate reductase activity
CP975_RS25335	COG2130	NADP-dependent
CP975_RS25340	COG0583	DNA-binding transcription factor activity
CP975_RS25355	COG0473	3-isopropylmalate dehydrogenase activity
CP975_RS25360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP975_RS25365	COG1309	transcriptional regulator
CP975_RS25380	COG0831	urea catabolic process
CP975_RS25380	COG0832	Belongs to the urease beta subunit family
CP975_RS25385	COG0804	urea catabolic process
CP975_RS25390	COG2957	Belongs to the agmatine deiminase family
CP975_RS25405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP975_RS25425	COG2353	YceI-like domain
CP975_RS25455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP975_RS25465	COG0583	DNA-binding transcription factor activity
CP975_RS25485	COG2018	Roadblock/LC7 domain
CP975_RS25505	COG2018	Roadblock/LC7 domain
CP975_RS25510	COG5002	protein histidine kinase activity
CP975_RS25520	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP975_RS25525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP975_RS25570	COG1414	Transcriptional regulator
CP975_RS25575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP975_RS25580	COG0066	3-isopropylmalate dehydratase activity
CP975_RS25590	COG0776	regulation of translation
CP975_RS25605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP975_RS25610	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP975_RS25630	COG0351	phosphomethylpyrimidine kinase
CP975_RS25645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP975_RS25650	COG1461	Dihydroxyacetone kinase
CP975_RS25660	COG0742	ribosomal rna small subunit methyltransferase
CP975_RS25665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP975_RS25680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP975_RS25685	COG0571	ribonuclease III activity
CP975_RS25690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP975_RS25695	COG1733	regulation of RNA biosynthetic process
CP975_RS25705	COG1254	Belongs to the acylphosphatase family
CP975_RS25715	COG1196	nuclear chromosome segregation
CP975_RS25720	COG0477	Major facilitator Superfamily
CP975_RS25760	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP975_RS25770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP975_RS25785	COG0228	four-way junction DNA binding
CP975_RS25790	COG1837	Belongs to the UPF0109 family
CP975_RS25795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP975_RS25800	COG0336	Belongs to the RNA methyltransferase TrmD family
CP975_RS25805	COG0335	large ribosomal subunit rRNA binding
CP975_RS25810	COG0681	Belongs to the peptidase S26 family
CP975_RS25815	COG0681	Belongs to the peptidase S26 family
CP975_RS25820	COG0681	Belongs to the peptidase S26 family
CP975_RS25830	COG1051	belongs to the nudix hydrolase family
CP975_RS25840	COG0792	nuclease activity
CP975_RS25855	COG1191	sigma factor activity
CP975_RS25865	COG4942	peptidase
CP975_RS25870	COG0052	Belongs to the universal ribosomal protein uS2 family
CP975_RS25875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP975_RS25880	COG0528	UMP kinase activity
CP975_RS25885	COG0233	cytoplasmic translational termination
CP975_RS25890	COG0575	Belongs to the CDS family
CP975_RS25895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP975_RS25910	COG3842	ATPase activity
CP975_RS25940	COG0784	Response regulator, receiver
CP975_RS25940	COG2205	protein histidine kinase activity
CP975_RS25940	COG5002	protein histidine kinase activity
CP975_RS25975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP975_RS25985	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS26015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS26020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS26030	COG1024	Enoyl-CoA hydratase
CP975_RS26045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP975_RS26060	COG0166	Belongs to the GPI family
CP975_RS26065	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP975_RS26070	COG0588	phosphoglycerate mutase activity
CP975_RS26085	COG1801	Protein of unknown function DUF72
CP975_RS26095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP975_RS26110	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS26120	COG3842	ATPase activity
CP975_RS26125	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP975_RS26130	COG1177	transmembrane transport
CP975_RS26135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP975_RS26160	COG2508	Transcriptional regulator
CP975_RS26160	COG2508	Transcriptional regulator
CP975_RS26165	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS26175	COG0653	protein targeting
CP975_RS26180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP975_RS26185	COG0750	zinc metalloprotease
CP975_RS26190	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP975_RS26205	COG0442	prolyl-tRNA aminoacylation
CP975_RS26225	COG0779	Required for maturation of 30S ribosomal subunits
CP975_RS26240	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP975_RS26250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP975_RS26255	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP975_RS26270	COG4608	Belongs to the ABC transporter superfamily
CP975_RS26275	COG0444	Belongs to the ABC transporter superfamily
CP975_RS26280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP975_RS26285	COG0601	transmembrane transport
CP975_RS26290	COG0747	negative chemotaxis
CP975_RS26295	COG0455	bacterial-type flagellum organization
CP975_RS26310	COG3266	domain, Protein
CP975_RS26345	COG1404	Belongs to the peptidase S8 family
CP975_RS26365	COG1674	ftsk spoiiie
CP975_RS26375	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP975_RS26380	COG1185	polyribonucleotide nucleotidyltransferase activity
CP975_RS26385	COG0612	Peptidase, M16
CP975_RS26390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP975_RS26410	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP975_RS26415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP975_RS26420	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP975_RS26460	COG2770	Histidine kinase
CP975_RS26460	COG2208	phosphoserine phosphatase activity
CP975_RS26470	COG4999	Histidine kinase
CP975_RS26470	COG3850	Histidine kinase
CP975_RS26470	COG3437	response regulator, receiver
CP975_RS26470	COG2205	protein histidine kinase activity
CP975_RS26480	COG1674	ftsk spoiiie
CP975_RS26490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP975_RS26500	COG1546	Belongs to the CinA family
CP975_RS26500	COG1058	Belongs to the CinA family
CP975_RS26505	COG1396	sequence-specific DNA binding
CP975_RS26510	COG0783	Belongs to the Dps family
CP975_RS26520	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS26525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP975_RS26530	COG1201	RNA secondary structure unwinding
CP975_RS26545	COG0628	permease
CP975_RS26555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP975_RS26575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP975_RS26590	COG0765	amino acid transport
CP975_RS26595	COG0765	amino acid transport
CP975_RS26600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP975_RS26605	COG1126	abc transporter atp-binding protein
CP975_RS26610	COG0745	RESPONSE REGULATOR receiver
CP975_RS26615	COG2205	protein histidine kinase activity
CP975_RS26625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP975_RS26645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP975_RS26655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP975_RS26660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP975_RS26670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP975_RS26710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP975_RS26715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP975_RS26720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP975_RS26745	COG0488	(ABC) transporter
CP975_RS26775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP975_RS26815	COG1802	Transcriptional regulator
CP975_RS26820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP975_RS26835	COG0187	DNA topoisomerase II activity
CP975_RS26845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP975_RS26850	COG4565	transcriptional regulatory protein
CP975_RS26855	COG3290	protein histidine kinase activity
CP975_RS26870	COG0372	Belongs to the citrate synthase family
CP975_RS26890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP975_RS26895	COG0612	Peptidase, M16
CP975_RS26905	COG0741	lytic transglycosylase activity
CP975_RS26905	COG0739	heme binding
CP975_RS26905	COG1196	nuclear chromosome segregation
CP975_RS26910	COG1802	Transcriptional regulator
CP975_RS26915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP975_RS26935	COG1435	thymidine kinase activity
CP975_RS26970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP975_RS26980	COG0745	RESPONSE REGULATOR receiver
CP975_RS26985	COG2205	protein histidine kinase activity
CP975_RS27010	COG0756	dUTP diphosphatase activity
CP975_RS27035	COG0577	efflux transmembrane transporter activity
CP975_RS27035	COG1136	(ABC) transporter
CP975_RS27040	COG1136	(ABC) transporter
CP975_RS27070	COG0569	domain protein
CP975_RS27090	COG0531	amino acid
CP975_RS27095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP975_RS27100	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CP975_RS27110	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CP975_RS27120	COG0464	growth
CP975_RS27130	COG1942	4-Oxalocrotonate Tautomerase
CP975_RS27150	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP975_RS27155	COG2197	response regulator
CP975_RS27170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS27185	COG2124	cytochrome p450
CP975_RS27190	COG2226	methyltransferase
CP975_RS27215	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CP975_RS27215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP975_RS27220	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP975_RS27250	COG2197	response regulator
CP975_RS27270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP975_RS27280	COG1819	glycosyl
CP975_RS27290	COG3321	synthase
CP975_RS27290	COG0604	alcohol dehydrogenase
CP975_RS27295	COG0604	alcohol dehydrogenase
CP975_RS27295	COG3321	synthase
CP975_RS27330	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS27335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP975_RS27345	COG4770	biotin carboxylase activity
CP975_RS27365	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS27370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP975_RS27380	COG3226	Transcriptional regulator
CP975_RS27405	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS27435	COG1113	amino acid transport
CP975_RS27440	COG4948	Mandelate Racemase Muconate Lactonizing
CP975_RS27480	COG0673	inositol 2-dehydrogenase activity
CP975_RS27500	COG2815	serine threonine protein kinase
CP975_RS27500	COG0515	serine threonine protein kinase
CP975_RS27555	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CP975_RS27570	COG1799	cell septum assembly
CP975_RS27665	COG3629	intracellular signal transduction
CP975_RS27665	COG3903	Transcriptional regulator
CP975_RS27680	COG1222	aaa ATPase
CP975_RS27690	COG2197	response regulator
CP975_RS27710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP975_RS27715	COG2235	arginine
CP975_RS27720	COG0531	amino acid
CP975_RS27745	COG1024	Enoyl-CoA hydratase
CP975_RS27785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP975_RS27795	COG1609	Transcriptional regulator
CP975_RS27805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP975_RS27835	COG1175	transmembrane transport
CP975_RS27840	COG0395	ABC-type sugar transport system, permease component
CP975_RS27855	COG0395	ABC-type sugar transport system, permease component
CP975_RS27860	COG1940	carbohydrate kinase activity
CP975_RS27865	COG4213	ABC transporter substrate-binding protein
CP975_RS27875	COG4214	carbohydrate transport
CP975_RS27880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP975_RS27885	COG0531	amino acid
CP975_RS27925	COG2843	Capsule synthesis protein
CP975_RS27960	COG1024	Enoyl-CoA hydratase
CP975_RS27960	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP975_RS27965	COG0183	Belongs to the thiolase family
CP975_RS27970	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CP975_RS27985	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP975_RS27995	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP975_RS28005	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP975_RS28010	COG3253	May function as heme-dependent peroxidase
CP975_RS28035	COG3220	belongs to the UPF0276 family
CP975_RS28060	COG0726	polysaccharide deacetylase
CP975_RS28065	COG2267	carboxylic ester hydrolase activity
CP975_RS28090	COG1022	Amp-dependent synthetase and ligase
CP975_RS28105	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP975_RS28105	COG1672	PFAM Archaeal ATPase
CP975_RS28115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP975_RS28120	COG0019	diaminopimelate decarboxylase activity
CP975_RS28135	COG4166	transmembrane transport
CP975_RS28140	COG0601	transmembrane transport
CP975_RS28145	COG4171	peptide transport system, permease
CP975_RS28155	COG2264	protein methyltransferase activity
CP975_RS28185	COG3568	Endonuclease Exonuclease Phosphatase
CP975_RS28210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP975_RS28215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP975_RS28220	COG2234	aminopeptidase activity
CP975_RS28220	COG4935	Belongs to the peptidase S8 family
CP975_RS28225	COG1869	D-ribose catabolic process
CP975_RS28230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP975_RS28235	COG1879	ABC-type sugar transport system periplasmic component
CP975_RS28240	COG1129	ABC transporter
CP975_RS28245	COG1609	Transcriptional regulator
CP975_RS28300	COG0443	Heat shock 70 kDa protein
CP975_RS28305	COG0443	Heat shock 70 kDa protein
CP975_RS28310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP975_RS28340	COG0504	CTP synthase activity
CP975_RS28345	COG0583	DNA-binding transcription factor activity
CP975_RS28500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP975_RS28505	COG1116	anion transmembrane transporter activity
CP975_RS28505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CP975_RS28525	COG0529	Catalyzes the synthesis of activated sulfate
CP975_RS28530	COG0175	sulfate reduction
CP975_RS28540	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP975_RS28555	COG1960	acyl-CoA dehydrogenase activity
CP975_RS28585	COG1051	belongs to the nudix hydrolase family
CP975_RS28625	COG2124	cytochrome p450
CP975_RS28630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP975_RS28635	COG1162	GTPase activity
CP975_RS28665	COG0028	Belongs to the TPP enzyme family
CP975_RS28690	COG1802	Transcriptional regulator
CP975_RS28700	COG3835	regulator
CP975_RS28720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP975_RS28725	COG2252	PERMEase
CP975_RS28770	COG0753	catalase activity
CP975_RS28780	COG0494	nUDIX hydrolase
CP975_RS28780	COG0406	alpha-ribazole phosphatase activity
CP975_RS28815	COG1132	(ABC) transporter
CP975_RS28830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CP975_RS28840	COG0789	Transcriptional regulator
CP975_RS28850	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP975_RS28885	COG0477	Major facilitator Superfamily
CP975_RS28915	COG0598	Magnesium transport protein CorA
CP975_RS28925	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS28955	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS28965	COG2814	Major facilitator Superfamily
CP975_RS28980	COG3960	tartronate-semialdehyde synthase activity
CP975_RS28990	COG0753	catalase activity
CP975_RS28995	COG2084	Dehydrogenase
CP975_RS29000	COG3622	Belongs to the hyi family
CP975_RS29020	COG2351	hydroxyisourate hydrolase activity
CP975_RS29030	COG2233	PERMEase
CP975_RS29040	COG2233	PERMEase
CP975_RS29045	COG4257	antibiotic catabolic process
CP975_RS29065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP975_RS29125	COG1733	regulation of RNA biosynthetic process
CP975_RS29150	COG2356	endonuclease I
CP975_RS29185	COG0588	phosphoglycerate mutase activity
CP975_RS29195	COG2304	oxidoreductase activity
CP975_RS29205	COG0789	Transcriptional regulator
CP975_RS29220	COG0436	Aminotransferase
CP975_RS29245	COG2234	aminopeptidase activity
CP975_RS29270	COG2264	protein methyltransferase activity
CP975_RS29275	COG0483	inositol monophosphate 1-phosphatase activity
CP975_RS29305	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP975_RS29310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP975_RS29315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP975_RS29325	COG1414	Transcriptional regulator
CP975_RS29330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP975_RS29335	COG4266	Belongs to the allantoicase family
CP975_RS29340	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS29365	COG2197	response regulator
CP975_RS29375	COG0673	inositol 2-dehydrogenase activity
CP975_RS29380	COG2188	Transcriptional regulator
CP975_RS29395	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP975_RS29405	COG1940	carbohydrate kinase activity
CP975_RS29430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP975_RS29450	COG3209	COG3209 Rhs family protein
CP975_RS29655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS29675	COG1126	abc transporter atp-binding protein
CP975_RS29680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP975_RS29685	COG0765	amino acid transport
CP975_RS29690	COG0765	amino acid transport
CP975_RS29700	COG1376	ErfK ybiS ycfS ynhG family protein
CP975_RS29710	COG0405	Gamma-glutamyltransferase
CP975_RS29715	COG0024	Methionine aminopeptidase
CP975_RS29745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP975_RS29750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP975_RS29755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP975_RS29800	COG0702	epimerase
CP975_RS29815	COG0483	inositol monophosphate 1-phosphatase activity
CP975_RS29835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP975_RS29845	COG1929	Belongs to the glycerate kinase type-1 family
CP975_RS29855	COG0410	ABC transporter
CP975_RS29870	COG0559	Belongs to the binding-protein-dependent transport system permease family
CP975_RS29885	COG0688	phosphatidylethanolamine metabolic process
CP975_RS29890	COG1960	acyl-CoA dehydrogenase activity
CP975_RS29900	COG2301	Belongs to the HpcH HpaI aldolase family
CP975_RS29905	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP975_RS29905	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP975_RS29910	COG0604	alcohol dehydrogenase
CP975_RS29920	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP975_RS29930	COG0251	oxidation-reduction process
CP975_RS29945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP975_RS29960	COG2208	phosphoserine phosphatase activity
CP975_RS29960	COG1366	Belongs to the anti-sigma-factor antagonist family
CP975_RS29960	COG2172	sigma factor antagonist activity
CP975_RS29965	COG2226	methyltransferase
CP975_RS29970	COG3973	AAA domain
CP975_RS29975	COG5297	Belongs to the glycosyl hydrolase family 6
CP975_RS29995	COG2066	Belongs to the glutaminase family
CP975_RS30005	COG4214	carbohydrate transport
CP975_RS30035	COG1414	Transcriptional regulator
CP975_RS30040	COG3386	PFAM SMP-30 Gluconolaconase
CP975_RS30050	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP975_RS30055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP975_RS30070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP975_RS30090	COG0640	Transcriptional regulator
CP975_RS30095	COG2249	NAD(P)H dehydrogenase (quinone) activity
CP975_RS30125	COG2362	D-Aminopeptidase
CP975_RS30130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP975_RS30140	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP975_RS30180	COG4948	Mandelate Racemase Muconate Lactonizing
CP975_RS30200	COG1793	dna ligase
CP975_RS30200	COG3285	dna ligase
CP975_RS30260	COG4106	trans-aconitate 2-methyltransferase activity
CP975_RS30270	COG0488	(ABC) transporter
CP975_RS30285	COG0248	Ppx GppA phosphatase
CP975_RS30290	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CP975_RS30300	COG1191	sigma factor activity
CP975_RS30355	COG0531	amino acid
CP975_RS30405	COG0443	Heat shock 70 kDa protein
CP975_RS30420	COG1140	nitrate reductase beta subunit
CP975_RS30440	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP975_RS30475	COG0656	L-ascorbic acid biosynthetic process
CP975_RS30485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CP975_RS30490	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CP975_RS30515	COG0477	Major facilitator Superfamily
CP975_RS30545	COG1063	alcohol dehydrogenase
CP975_RS30555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP975_RS30560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP975_RS30565	COG2050	protein possibly involved in aromatic compounds catabolism
CP975_RS30585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP975_RS30595	COG3938	Belongs to the proline racemase family
CP975_RS30615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP975_RS30620	COG2207	Transcriptional regulator
CP975_RS30625	COG2223	nitrite transmembrane transporter activity
CP975_RS30635	COG1472	Belongs to the glycosyl hydrolase 3 family
CP975_RS30640	COG1063	alcohol dehydrogenase
CP975_RS30645	COG0673	inositol 2-dehydrogenase activity
CP975_RS30665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP975_RS30700	COG0583	DNA-binding transcription factor activity
CP975_RS30710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP975_RS30715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP975_RS30730	COG0477	Major facilitator Superfamily
CP975_RS30740	COG1486	melibiose metabolic process
CP975_RS30755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP975_RS30760	COG3511	phospholipase C
CP975_RS30795	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CP975_RS30800	COG1960	acyl-CoA dehydrogenase activity
CP975_RS30805	COG1960	acyl-CoA dehydrogenase activity
CP975_RS30815	COG1309	transcriptional regulator
CP975_RS30820	COG0183	Belongs to the thiolase family
CP975_RS30825	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP975_RS30825	COG1672	PFAM Archaeal ATPase
CP975_RS30845	COG1024	Enoyl-CoA hydratase
CP975_RS30855	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS30860	COG0596	Alpha beta hydrolase
CP975_RS30865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP975_RS30870	COG3485	protocatechuate 3,4-dioxygenase
CP975_RS30875	COG3485	protocatechuate 3,4-dioxygenase
CP975_RS30890	COG1846	Transcriptional regulator
CP975_RS30905	COG1793	dna ligase
CP975_RS30910	COG3285	dna ligase
CP975_RS30910	COG1793	dna ligase
CP975_RS30950	COG1834	amidinotransferase
CP975_RS30955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP975_RS30960	COG0488	(ABC) transporter
CP975_RS30970	COG1522	sequence-specific DNA binding
CP975_RS30995	COG2268	Band 7 protein
CP975_RS31000	COG1585	Membrane protein implicated in regulation of membrane protease activity
CP975_RS31005	COG1515	deoxyribonuclease V activity
CP975_RS31015	COG3268	Saccharopine dehydrogenase
CP975_RS31020	COG1683	Conserved Protein
CP975_RS31025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP975_RS31035	COG0183	Belongs to the thiolase family
CP975_RS31040	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP975_RS31040	COG1024	Enoyl-CoA hydratase
CP975_RS31045	COG0789	Transcriptional regulator
CP975_RS31055	COG1113	amino acid transport
CP975_RS31060	COG2267	carboxylic ester hydrolase activity
CP975_RS31075	COG2936	dipeptidyl-peptidase activity
CP975_RS31085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP975_RS31095	COG0488	(ABC) transporter
CP975_RS31100	COG2183	response to ionizing radiation
CP975_RS31110	COG4977	sequence-specific DNA binding
CP975_RS31120	COG1024	Enoyl-CoA hydratase
CP975_RS31140	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP975_RS31190	COG1134	teichoic acid transport
CP975_RS31195	COG1562	ergosterol biosynthetic process
CP975_RS31205	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP975_RS31215	COG1657	PFAM Prenyltransferase squalene oxidase
CP975_RS31230	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP975_RS31250	COG2365	Tyrosine phosphatase family
CP975_RS31255	COG2755	lipolytic protein G-D-S-L family
CP975_RS31305	COG1063	alcohol dehydrogenase
CP975_RS31310	COG0156	8-amino-7-oxononanoate synthase activity
CP975_RS31320	COG0583	DNA-binding transcription factor activity
CP975_RS31335	COG2267	carboxylic ester hydrolase activity
CP975_RS31360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP975_RS31365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP975_RS31370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP975_RS31380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP975_RS31405	COG0668	transmembrane transport
CP975_RS31420	COG1175	transmembrane transport
CP975_RS31425	COG0395	ABC-type sugar transport system, permease component
CP975_RS31435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP975_RS31465	COG0183	Belongs to the thiolase family
CP975_RS31470	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS31500	COG0745	RESPONSE REGULATOR receiver
CP975_RS31505	COG2205	protein histidine kinase activity
CP975_RS31510	COG4249	Peptidase C14 caspase catalytic subunit p20
CP975_RS31510	COG2319	Wd-40 repeat
CP975_RS31520	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS31540	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP975_RS31575	COG2890	protein-(glutamine-N5) methyltransferase activity
CP975_RS31590	COG1012	belongs to the aldehyde dehydrogenase family
CP975_RS31620	COG2186	Transcriptional regulator
CP975_RS31625	COG2807	transmembrane transport
CP975_RS31645	COG1132	(ABC) transporter
CP975_RS31655	COG1063	alcohol dehydrogenase
CP975_RS31660	COG0154	amidase activity
CP975_RS31670	COG0300	oxidoreductase activity
CP975_RS31680	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP975_RS31715	COG0297	glycogen (starch) synthase activity
CP975_RS31720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP975_RS31740	COG1609	Transcriptional regulator
CP975_RS31745	COG1653	transport
CP975_RS31750	COG1175	transmembrane transport
CP975_RS31755	COG0395	ABC-type sugar transport system, permease component
CP975_RS31780	COG2197	response regulator
CP975_RS31785	COG0745	RESPONSE REGULATOR receiver
CP975_RS31790	COG2205	protein histidine kinase activity
CP975_RS31795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CP975_RS31810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP975_RS31830	COG0531	amino acid
CP975_RS31840	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP975_RS31840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP975_RS31910	COG1053	succinate dehydrogenase
CP975_RS31915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP975_RS31945	COG3424	synthase
CP975_RS31950	COG1024	Enoyl-CoA hydratase
CP975_RS31955	COG1024	Enoyl-CoA hydratase
CP975_RS31960	COG2267	carboxylic ester hydrolase activity
CP975_RS31970	COG1132	(ABC) transporter
CP975_RS31975	COG2205	protein histidine kinase activity
CP975_RS32005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS32010	COG2124	cytochrome p450
CP975_RS32015	COG2124	cytochrome p450
CP975_RS32020	COG2124	cytochrome p450
CP975_RS32040	COG1136	(ABC) transporter
CP975_RS32040	COG0577	efflux transmembrane transporter activity
CP975_RS32045	COG1136	(ABC) transporter
CP975_RS32045	COG0577	efflux transmembrane transporter activity
CP975_RS32050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP975_RS32060	COG2182	Extracellular solute-binding protein
CP975_RS32065	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CP975_RS32070	COG0121	glutamine amidotransferase
CP975_RS32075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP975_RS32095	COG1609	Transcriptional regulator
CP975_RS32100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP975_RS32135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP975_RS32140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP975_RS32150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CP975_RS32175	COG3903	Transcriptional regulator
CP975_RS32175	COG3629	intracellular signal transduction
CP975_RS32220	COG2267	carboxylic ester hydrolase activity
CP975_RS32225	COG1131	(ABC) transporter
CP975_RS32225	COG0842	Transport permease protein
CP975_RS32225	COG1716	ATPase activity
CP975_RS32265	COG2226	methyltransferase
CP975_RS32305	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP975_RS32320	COG1595	DNA-templated transcription, initiation
CP975_RS32370	COG0513	Belongs to the DEAD box helicase family
CP975_RS32410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP975_RS32415	COG0640	Transcriptional regulator
CP975_RS32420	COG0798	PFAM Bile acid sodium symporter
CP975_RS32425	COG0640	Transcriptional regulator
CP975_RS32470	COG1595	DNA-templated transcription, initiation
CP975_RS32530	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS32555	COG2010	Cytochrome c
CP975_RS32555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP975_RS32565	COG1280	lysine exporter protein (LysE YggA)
CP975_RS32575	COG0640	Transcriptional regulator
CP975_RS32595	COG1960	acyl-CoA dehydrogenase activity
CP975_RS32625	COG0515	serine threonine protein kinase
CP975_RS32635	COG1309	transcriptional regulator
CP975_RS32645	COG2070	2-Nitropropane dioxygenase
CP975_RS32660	COG0318	PFAM AMP-dependent synthetase and ligase
CP975_RS32675	COG2267	carboxylic ester hydrolase activity
CP975_RS32690	COG1024	Enoyl-CoA hydratase
CP975_RS32715	COG2084	Dehydrogenase
CP975_RS32755	COG0181	hydroxymethylbilane synthase activity
CP975_RS32790	COG1793	dna ligase
CP975_RS32800	COG1686	Belongs to the peptidase S11 family
CP975_RS32820	COG0386	Belongs to the glutathione peroxidase family
CP975_RS32855	COG2706	6-phosphogluconolactonase activity
CP975_RS32900	COG0435	Glutathione S-transferase
CP975_RS32915	COG1309	transcriptional regulator
CP975_RS32930	COG0738	Major facilitator superfamily
CP975_RS32940	COG1132	(ABC) transporter
CP975_RS32990	COG3590	peptidase
CP975_RS32995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP975_RS33000	COG1396	sequence-specific DNA binding
CP975_RS33000	COG3800	Transcriptional regulator
CP975_RS33005	COG0596	Alpha beta hydrolase
CP975_RS33045	COG1609	Transcriptional regulator
CP975_RS33050	COG1957	nucleoside hydrolase
CP975_RS33055	COG0477	Major facilitator Superfamily
CP975_RS33065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP975_RS33095	COG3629	intracellular signal transduction
CP975_RS33095	COG3903	Transcriptional regulator
CP975_RS33100	COG2124	cytochrome p450
CP975_RS33115	COG1982	Orn Lys Arg decarboxylase major
CP975_RS33125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP975_RS33125	COG1796	DNA polymerase
CP975_RS33130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP975_RS33135	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP975_RS33140	COG2080	2 iron, 2 sulfur cluster binding
CP975_RS33160	COG0328	RNA-DNA hybrid ribonuclease activity
CP975_RS33225	COG0596	Alpha beta hydrolase
CP975_RS33230	COG2770	Histidine kinase
CP975_RS33230	COG2208	phosphoserine phosphatase activity
CP975_RS33245	COG0142	geranyltranstransferase activity
CP975_RS33290	COG1595	DNA-templated transcription, initiation
CP975_RS33320	COG0367	asparagine synthase
CP975_RS33325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP975_RS33335	COG0657	acetylesterase activity
CP975_RS33340	COG2072	flavoprotein involved in K transport
CP975_RS33345	COG0277	FAD linked oxidase domain protein
CP975_RS33360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CP975_RS33365	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS33370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS33375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CP975_RS33380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP975_RS33385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS33415	COG2409	Drug exporters of the RND superfamily
CP975_RS33445	COG2197	response regulator
CP975_RS33450	COG4585	Histidine kinase
CP975_RS33470	COG2311	Membrane
CP975_RS33610	COG2197	response regulator
CP975_RS33620	COG2226	methyltransferase
CP975_RS33625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP975_RS33640	COG4221	oxidoreductase activity
CP975_RS33650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP975_RS33655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP975_RS33670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP975_RS33690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP975_RS33695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP975_RS33725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CP975_RS33740	COG3251	PFAM MbtH domain protein
CP975_RS33745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS33760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS33800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP975_RS33805	COG2234	aminopeptidase activity
CP975_RS33855	COG3835	regulator
CP975_RS33860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP975_RS33865	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CP975_RS33875	COG1280	lysine exporter protein (LysE YggA)
CP975_RS33885	COG0367	asparagine synthase
CP975_RS33890	COG1902	pentaerythritol trinitrate reductase activity
CP975_RS33925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP975_RS34040	COG1960	acyl-CoA dehydrogenase activity
CP975_RS34045	COG1960	acyl-CoA dehydrogenase activity
CP975_RS34050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP975_RS34055	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP975_RS34065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP975_RS34070	COG3959	Transketolase, thiamine diphosphate binding domain
CP975_RS34080	COG0189	ligase activity
CP975_RS34085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP975_RS34100	COG1280	lysine exporter protein (LysE YggA)
CP975_RS34110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP975_RS34140	COG2815	serine threonine protein kinase
CP975_RS34140	COG0515	serine threonine protein kinase
CP975_RS34260	COG1132	(ABC) transporter
CP975_RS34330	COG1648	precorrin-2 dehydrogenase activity
CP975_RS34330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP975_RS34360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CP975_RS34390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS34420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP975_RS34445	COG1064	alcohol dehydrogenase
CP975_RS34450	COG1309	transcriptional regulator
CP975_RS34470	COG0583	DNA-binding transcription factor activity
CP975_RS34480	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CP975_RS34590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP975_RS34605	COG1595	DNA-templated transcription, initiation
CP975_RS34620	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CP975_RS34675	COG2318	DinB family
CP975_RS34735	COG1028	Short-chain dehydrogenase reductase Sdr
CP975_RS34755	COG2304	oxidoreductase activity
CP975_RS34790	COG0477	Major facilitator Superfamily
CP975_RS34845	COG0739	heme binding