locus-tag	class	description
SE95_RS00040	COG3328	transposase activity
SE95_RS00055	COG0662	Cupin 2, conserved barrel domain protein
SE95_RS00125	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS00170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SE95_RS00210	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SE95_RS00215	COG3118	belongs to the thioredoxin family
SE95_RS00265	COG0346	lactoylglutathione lyase activity
SE95_RS00270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SE95_RS00280	COG0798	PFAM Bile acid sodium symporter
SE95_RS00285	COG0789	Transcriptional regulator
SE95_RS00295	COG2205	protein histidine kinase activity
SE95_RS00300	COG0745	RESPONSE REGULATOR receiver
SE95_RS00315	COG2755	lipolytic protein G-D-S-L family
SE95_RS00315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SE95_RS00325	COG0154	amidase activity
SE95_RS00330	COG1609	Transcriptional regulator
SE95_RS00390	COG1733	regulation of RNA biosynthetic process
SE95_RS00395	COG0596	Alpha beta hydrolase
SE95_RS00400	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS00410	COG0583	DNA-binding transcription factor activity
SE95_RS00435	COG0019	diaminopimelate decarboxylase activity
SE95_RS00450	COG0531	amino acid
SE95_RS00455	COG2197	response regulator
SE95_RS00460	COG4585	Histidine kinase
SE95_RS00485	COG0285	dihydrofolate synthase activity
SE95_RS00525	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS00535	COG3483	tryptophan 2,3-dioxygenase activity
SE95_RS00545	COG2192	nodulation
SE95_RS00550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SE95_RS00555	COG2226	methyltransferase
SE95_RS00580	COG4221	oxidoreductase activity
SE95_RS00655	COG2205	protein histidine kinase activity
SE95_RS00660	COG0745	RESPONSE REGULATOR receiver
SE95_RS00675	COG2267	carboxylic ester hydrolase activity
SE95_RS00680	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SE95_RS00690	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS00710	COG0154	amidase activity
SE95_RS00715	COG1309	transcriptional regulator
SE95_RS00725	COG1733	regulation of RNA biosynthetic process
SE95_RS00730	COG0604	alcohol dehydrogenase
SE95_RS00790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SE95_RS00820	COG1309	transcriptional regulator
SE95_RS00860	COG1620	l-lactate permease
SE95_RS00870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SE95_RS00875	COG0247	lactate metabolic process
SE95_RS00875	COG0277	FAD linked oxidase domain protein
SE95_RS00905	COG3290	protein histidine kinase activity
SE95_RS00910	COG1309	transcriptional regulator
SE95_RS00925	COG2226	methyltransferase
SE95_RS00990	COG0516	GMP reductase activity
SE95_RS00990	COG0517	IMP dehydrogenase activity
SE95_RS00995	COG0516	GMP reductase activity
SE95_RS00995	COG0517	IMP dehydrogenase activity
SE95_RS01000	COG0516	GMP reductase activity
SE95_RS01000	COG0517	IMP dehydrogenase activity
SE95_RS01005	COG2326	polyphosphate kinase activity
SE95_RS01010	COG0745	RESPONSE REGULATOR receiver
SE95_RS01015	COG2205	protein histidine kinase activity
SE95_RS01160	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SE95_RS01165	COG2272	Belongs to the type-B carboxylesterase lipase family
SE95_RS01195	COG2814	Major facilitator Superfamily
SE95_RS01200	COG2124	cytochrome p450
SE95_RS01220	COG1595	DNA-templated transcription, initiation
SE95_RS01290	COG0583	DNA-binding transcription factor activity
SE95_RS01295	COG2814	Major facilitator Superfamily
SE95_RS01310	COG4585	Histidine kinase
SE95_RS01315	COG2197	response regulator
SE95_RS01345	COG1846	Transcriptional regulator
SE95_RS01395	COG3903	Transcriptional regulator
SE95_RS01395	COG3629	intracellular signal transduction
SE95_RS01445	COG4585	Histidine kinase
SE95_RS01455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SE95_RS01495	COG0494	nUDIX hydrolase
SE95_RS01520	COG1063	alcohol dehydrogenase
SE95_RS01585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SE95_RS01590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SE95_RS01595	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SE95_RS01640	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SE95_RS01640	COG0515	serine threonine protein kinase
SE95_RS01675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS01730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SE95_RS01750	COG0477	Major facilitator Superfamily
SE95_RS01760	COG4941	Belongs to the sigma-70 factor family
SE95_RS01770	COG1064	alcohol dehydrogenase
SE95_RS01790	COG1611	Belongs to the LOG family
SE95_RS01805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SE95_RS01840	COG0702	epimerase
SE95_RS01845	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SE95_RS01870	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS01875	COG0477	Major facilitator Superfamily
SE95_RS01880	COG1819	glycosyl
SE95_RS01885	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SE95_RS01895	COG0328	RNA-DNA hybrid ribonuclease activity
SE95_RS01905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SE95_RS01910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SE95_RS01940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS01965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SE95_RS01970	COG2188	Transcriptional regulator
SE95_RS02065	COG1181	Belongs to the D-alanine--D-alanine ligase family
SE95_RS02125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SE95_RS02135	COG3485	protocatechuate 3,4-dioxygenase
SE95_RS02165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SE95_RS02170	COG3340	Belongs to the peptidase S51 family
SE95_RS02220	COG4585	Histidine kinase
SE95_RS02225	COG2197	response regulator
SE95_RS02240	COG1090	epimerase
SE95_RS02250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SE95_RS02295	COG4948	Mandelate Racemase Muconate Lactonizing
SE95_RS02300	COG0179	Fumarylacetoacetate (FAA) hydrolase
SE95_RS02310	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SE95_RS02315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SE95_RS02320	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SE95_RS02330	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS02345	COG2197	response regulator
SE95_RS02350	COG1942	4-Oxalocrotonate Tautomerase
SE95_RS02380	COG0590	tRNA wobble adenosine to inosine editing
SE95_RS02395	COG0583	DNA-binding transcription factor activity
SE95_RS02425	COG0488	(ABC) transporter
SE95_RS02430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS02435	COG2318	DinB family
SE95_RS02440	COG0326	Molecular chaperone. Has ATPase activity
SE95_RS02480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SE95_RS02485	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SE95_RS02490	COG1473	amidohydrolase
SE95_RS02495	COG0477	Major facilitator Superfamily
SE95_RS02505	COG2124	cytochrome p450
SE95_RS02510	COG0596	Alpha beta hydrolase
SE95_RS02535	COG1414	Transcriptional regulator
SE95_RS02540	COG1461	Dihydroxyacetone kinase
SE95_RS02545	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SE95_RS02565	COG0697	spore germination
SE95_RS02580	COG1254	Belongs to the acylphosphatase family
SE95_RS02595	COG2197	response regulator
SE95_RS02610	COG3340	Belongs to the peptidase S51 family
SE95_RS02630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SE95_RS02650	COG2267	carboxylic ester hydrolase activity
SE95_RS02660	COG0656	L-ascorbic acid biosynthetic process
SE95_RS02665	COG2814	Major facilitator Superfamily
SE95_RS02685	COG3848	Pyruvate phosphate dikinase
SE95_RS02685	COG0574	Belongs to the PEP-utilizing enzyme family
SE95_RS02710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SE95_RS02755	COG0640	Transcriptional regulator
SE95_RS02765	COG1695	Transcriptional regulator
SE95_RS02835	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS02840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SE95_RS02845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS02850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SE95_RS02855	COG1335	isochorismatase
SE95_RS02880	COG5006	permease, DMT superfamily
SE95_RS02885	COG0583	DNA-binding transcription factor activity
SE95_RS02895	COG0738	Major facilitator superfamily
SE95_RS02910	COG0583	DNA-binding transcription factor activity
SE95_RS02915	COG0473	3-isopropylmalate dehydrogenase activity
SE95_RS02940	COG0604	alcohol dehydrogenase
SE95_RS02940	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS02940	COG3321	synthase
SE95_RS03035	COG3753	Protein conserved in bacteria
SE95_RS03110	COG0640	Transcriptional regulator
SE95_RS03115	COG1116	anion transmembrane transporter activity
SE95_RS03160	COG0745	RESPONSE REGULATOR receiver
SE95_RS03165	COG1285	pathogenesis
SE95_RS03185	COG0009	L-threonylcarbamoyladenylate synthase
SE95_RS03360	COG1595	DNA-templated transcription, initiation
SE95_RS03375	COG1960	acyl-CoA dehydrogenase activity
SE95_RS03385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SE95_RS03395	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS03405	COG0531	amino acid
SE95_RS03540	COG3629	intracellular signal transduction
SE95_RS03540	COG3903	Transcriptional regulator
SE95_RS03555	COG3903	Transcriptional regulator
SE95_RS03555	COG3629	intracellular signal transduction
SE95_RS03575	COG3547	Transposase (IS116 IS110 IS902 family)
SE95_RS03600	COG4977	sequence-specific DNA binding
SE95_RS03615	COG2124	cytochrome p450
SE95_RS03675	COG3655	Transcriptional regulator
SE95_RS03680	COG0644	oxidoreductase
SE95_RS03735	COG0702	epimerase
SE95_RS03770	COG3631	Ketosteroid isomerase-related protein
SE95_RS03775	COG0702	epimerase
SE95_RS03790	COG2345	Transcriptional regulator
SE95_RS03810	COG3033	Beta-eliminating lyase
SE95_RS03825	COG0513	Belongs to the DEAD box helicase family
SE95_RS03855	COG0739	heme binding
SE95_RS03855	COG1196	nuclear chromosome segregation
SE95_RS03855	COG0741	lytic transglycosylase activity
SE95_RS03890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SE95_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS03930	COG3850	Histidine kinase
SE95_RS03955	COG0477	Major facilitator Superfamily
SE95_RS03960	COG2226	methyltransferase
SE95_RS03965	COG0488	(ABC) transporter
SE95_RS03990	COG1309	transcriptional regulator
SE95_RS04005	COG3547	Transposase (IS116 IS110 IS902 family)
SE95_RS04015	COG2272	Belongs to the type-B carboxylesterase lipase family
SE95_RS04020	COG3226	Transcriptional regulator
SE95_RS04040	COG2208	phosphoserine phosphatase activity
SE95_RS04040	COG2770	Histidine kinase
SE95_RS04060	COG1366	Belongs to the anti-sigma-factor antagonist family
SE95_RS04065	COG1191	sigma factor activity
SE95_RS04070	COG1819	glycosyl
SE95_RS04135	COG0701	Predicted permease
SE95_RS04140	COG0745	RESPONSE REGULATOR receiver
SE95_RS04145	COG2205	protein histidine kinase activity
SE95_RS04160	COG1959	2 iron, 2 sulfur cluster binding
SE95_RS04180	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS04185	COG0583	DNA-binding transcription factor activity
SE95_RS04205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SE95_RS04235	COG1595	DNA-templated transcription, initiation
SE95_RS04240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SE95_RS04250	COG2080	2 iron, 2 sulfur cluster binding
SE95_RS04255	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SE95_RS04260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SE95_RS04290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SE95_RS04305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SE95_RS04310	COG2124	cytochrome p450
SE95_RS04345	COG3387	PFAM Glycoside hydrolase 15-related
SE95_RS04355	COG0667	Aldo Keto reductase
SE95_RS04370	COG2226	methyltransferase
SE95_RS04385	COG2226	methyltransferase
SE95_RS04405	COG4221	oxidoreductase activity
SE95_RS04425	COG2318	DinB family
SE95_RS04450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SE95_RS04470	COG2226	methyltransferase
SE95_RS04475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SE95_RS04480	COG1993	acr, cog1993
SE95_RS04485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SE95_RS04495	COG0531	amino acid
SE95_RS04520	COG2084	Dehydrogenase
SE95_RS04530	COG2197	response regulator
SE95_RS04545	COG1115	amino acid carrier protein
SE95_RS04550	COG0745	RESPONSE REGULATOR receiver
SE95_RS04560	COG0741	lytic transglycosylase activity
SE95_RS04560	COG0791	NLP P60 protein
SE95_RS04585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SE95_RS04600	COG2329	Antibiotic biosynthesis monooxygenase
SE95_RS04620	COG0745	RESPONSE REGULATOR receiver
SE95_RS04630	COG2239	Acts as a magnesium transporter
SE95_RS04670	COG0181	hydroxymethylbilane synthase activity
SE95_RS04705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SE95_RS04715	COG1794	racemase activity, acting on amino acids and derivatives
SE95_RS04765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SE95_RS04785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS04800	COG2124	cytochrome p450
SE95_RS04860	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS04870	COG2409	Drug exporters of the RND superfamily
SE95_RS04890	COG1271	oxidase subunit
SE95_RS04895	COG1294	oxidase, subunit
SE95_RS04900	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS04930	COG0577	efflux transmembrane transporter activity
SE95_RS04935	COG1136	(ABC) transporter
SE95_RS04935	COG0577	efflux transmembrane transporter activity
SE95_RS05010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SE95_RS05030	COG0604	alcohol dehydrogenase
SE95_RS05055	COG0492	ferredoxin-NADP+ reductase activity
SE95_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS05090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SE95_RS05105	COG2124	cytochrome p450
SE95_RS05110	COG0604	alcohol dehydrogenase
SE95_RS05115	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SE95_RS05125	COG0789	Transcriptional regulator
SE95_RS05130	COG1802	Transcriptional regulator
SE95_RS05135	COG0596	Alpha beta hydrolase
SE95_RS05145	COG3387	PFAM Glycoside hydrolase 15-related
SE95_RS05180	COG1902	pentaerythritol trinitrate reductase activity
SE95_RS05190	COG1335	isochorismatase
SE95_RS05200	COG0583	DNA-binding transcription factor activity
SE95_RS05205	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS05250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SE95_RS05255	COG4988	ABC transporter
SE95_RS05265	COG1271	oxidase subunit
SE95_RS05270	COG0783	Belongs to the Dps family
SE95_RS05275	COG2814	Major facilitator Superfamily
SE95_RS05280	COG3619	membrane
SE95_RS05285	COG2259	Doxx family
SE95_RS05290	COG1335	isochorismatase
SE95_RS05300	COG0300	oxidoreductase activity
SE95_RS05305	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS05335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SE95_RS05360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SE95_RS05390	COG0367	asparagine synthase
SE95_RS05395	COG2814	Major facilitator Superfamily
SE95_RS05400	COG2608	mercury ion transmembrane transporter activity
SE95_RS05405	COG1120	ATPase activity
SE95_RS05410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS05445	COG1595	DNA-templated transcription, initiation
SE95_RS05470	COG2165	general secretion pathway protein
SE95_RS05495	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SE95_RS05500	COG4968	Prepilin-type N-terminal cleavage methylation domain
SE95_RS05505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SE95_RS05510	COG1459	type II secretion system
SE95_RS05535	COG0202	RNA polymerase activity
SE95_RS05555	COG1124	(ABC) transporter
SE95_RS05560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SE95_RS05565	COG0601	transmembrane transport
SE95_RS05570	COG4166	transmembrane transport
SE95_RS05585	COG4948	Mandelate Racemase Muconate Lactonizing
SE95_RS05590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SE95_RS05615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SE95_RS05640	COG2132	Multicopper oxidase
SE95_RS05655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SE95_RS05680	COG0477	Major facilitator Superfamily
SE95_RS05685	COG1960	acyl-CoA dehydrogenase activity
SE95_RS05690	COG1024	Enoyl-CoA hydratase
SE95_RS05695	COG1960	acyl-CoA dehydrogenase activity
SE95_RS05705	COG1960	acyl-CoA dehydrogenase activity
SE95_RS05710	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS05720	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS05730	COG2186	Transcriptional regulator
SE95_RS05760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SE95_RS05815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SE95_RS05830	COG4310	Domain of unknown function (DUF2172)
SE95_RS05840	COG1215	transferase activity, transferring glycosyl groups
SE95_RS05855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SE95_RS05900	COG1937	Protein conserved in bacteria
SE95_RS05915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SE95_RS05990	COG0300	oxidoreductase activity
SE95_RS05995	COG1309	transcriptional regulator
SE95_RS06010	COG0069	glutamate synthase activity
SE95_RS06025	COG3629	intracellular signal transduction
SE95_RS06025	COG3903	Transcriptional regulator
SE95_RS06030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS06035	COG3251	PFAM MbtH domain protein
SE95_RS06040	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SE95_RS06045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS06070	COG2208	phosphoserine phosphatase activity
SE95_RS06075	COG2172	sigma factor antagonist activity
SE95_RS06080	COG2172	sigma factor antagonist activity
SE95_RS06085	COG1366	Belongs to the anti-sigma-factor antagonist family
SE95_RS06090	COG1366	Belongs to the anti-sigma-factor antagonist family
SE95_RS06115	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SE95_RS06125	COG1280	lysine exporter protein (LysE YggA)
SE95_RS06140	COG2814	Major facilitator Superfamily
SE95_RS06145	COG0604	alcohol dehydrogenase
SE95_RS06160	COG3973	AAA domain
SE95_RS06195	COG2986	histidine ammonia-lyase
SE95_RS06200	COG0477	Major facilitator Superfamily
SE95_RS06220	COG0789	Transcriptional regulator
SE95_RS06225	COG0667	Aldo Keto reductase
SE95_RS06245	COG2205	protein histidine kinase activity
SE95_RS06250	COG0745	RESPONSE REGULATOR receiver
SE95_RS06255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SE95_RS06255	COG1017	nitric oxide dioxygenase activity
SE95_RS06270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SE95_RS06320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS06320	COG4221	oxidoreductase activity
SE95_RS06320	COG3321	synthase
SE95_RS06320	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS06330	COG3251	PFAM MbtH domain protein
SE95_RS06335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SE95_RS06380	COG2135	peptidase activity
SE95_RS06390	COG2205	protein histidine kinase activity
SE95_RS06395	COG0745	RESPONSE REGULATOR receiver
SE95_RS06400	COG0577	efflux transmembrane transporter activity
SE95_RS06405	COG1136	(ABC) transporter
SE95_RS06430	COG1309	transcriptional regulator
SE95_RS06460	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS06465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS06485	COG0402	S-adenosylhomocysteine deaminase activity
SE95_RS06500	COG0789	Transcriptional regulator
SE95_RS06520	COG1309	transcriptional regulator
SE95_RS06525	COG0659	secondary active sulfate transmembrane transporter activity
SE95_RS06535	COG0583	DNA-binding transcription factor activity
SE95_RS06545	COG0515	serine threonine protein kinase
SE95_RS06545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SE95_RS06550	COG0515	serine threonine protein kinase
SE95_RS06550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SE95_RS06560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SE95_RS06590	COG1113	amino acid transport
SE95_RS06595	COG3224	Antibiotic biosynthesis monooxygenase
SE95_RS06615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SE95_RS06620	COG0477	Major facilitator Superfamily
SE95_RS06630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SE95_RS06645	COG1846	Transcriptional regulator
SE95_RS06645	COG0456	acetyltransferase
SE95_RS06655	COG0513	Belongs to the DEAD box helicase family
SE95_RS06660	COG1278	Cold shock
SE95_RS06700	COG3979	chitinase
SE95_RS06730	COG1472	Belongs to the glycosyl hydrolase 3 family
SE95_RS06735	COG2124	cytochrome p450
SE95_RS06760	COG3387	PFAM Glycoside hydrolase 15-related
SE95_RS06790	COG0300	oxidoreductase activity
SE95_RS06795	COG0189	ligase activity
SE95_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS06830	COG2124	cytochrome p450
SE95_RS06845	COG0542	response to heat
SE95_RS06900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SE95_RS06910	COG3290	protein histidine kinase activity
SE95_RS06915	COG4565	transcriptional regulatory protein
SE95_RS06930	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SE95_RS06955	COG0583	DNA-binding transcription factor activity
SE95_RS06965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SE95_RS06970	COG0076	glutamate decarboxylase activity
SE95_RS07000	COG2186	Transcriptional regulator
SE95_RS07005	COG1027	Aspartate ammonia-lyase
SE95_RS07015	COG0640	Transcriptional regulator
SE95_RS07060	COG0529	Catalyzes the synthesis of activated sulfate
SE95_RS07070	COG0583	DNA-binding transcription factor activity
SE95_RS07130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SE95_RS07145	COG3321	synthase
SE95_RS07145	COG0604	alcohol dehydrogenase
SE95_RS07150	COG2365	Tyrosine phosphatase family
SE95_RS07155	COG3321	synthase
SE95_RS07155	COG0604	alcohol dehydrogenase
SE95_RS07165	COG0604	alcohol dehydrogenase
SE95_RS07165	COG3321	synthase
SE95_RS07235	COG2197	response regulator
SE95_RS07240	COG4585	Histidine kinase
SE95_RS07250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SE95_RS07260	COG0494	nUDIX hydrolase
SE95_RS07280	COG0531	amino acid
SE95_RS07290	COG0772	Belongs to the SEDS family
SE95_RS07305	COG1674	ftsk spoiiie
SE95_RS07320	COG0076	glutamate decarboxylase activity
SE95_RS07345	COG2124	cytochrome p450
SE95_RS07365	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SE95_RS07385	COG1309	transcriptional regulator
SE95_RS07400	COG2309	aminopeptidase activity
SE95_RS07410	COG0477	Major facilitator Superfamily
SE95_RS07435	COG1335	isochorismatase
SE95_RS07440	COG0596	Alpha beta hydrolase
SE95_RS07460	COG1653	transport
SE95_RS07510	COG2274	protein secretion by the type I secretion system
SE95_RS07525	COG1796	DNA polymerase
SE95_RS07525	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SE95_RS07530	COG0583	DNA-binding transcription factor activity
SE95_RS07535	COG0156	8-amino-7-oxononanoate synthase activity
SE95_RS07540	COG1063	alcohol dehydrogenase
SE95_RS07565	COG2318	DinB family
SE95_RS07600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SE95_RS07605	COG5504	Zn-dependent protease
SE95_RS07625	COG0745	RESPONSE REGULATOR receiver
SE95_RS07630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SE95_RS07630	COG1024	Enoyl-CoA hydratase
SE95_RS07645	COG0477	Major facilitator Superfamily
SE95_RS07680	COG3585	molybdate ion transport
SE95_RS07695	COG2080	2 iron, 2 sulfur cluster binding
SE95_RS07695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SE95_RS07700	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SE95_RS07705	COG3835	regulator
SE95_RS07740	COG2226	methyltransferase
SE95_RS07780	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SE95_RS07805	COG0438	transferase activity, transferring glycosyl groups
SE95_RS07840	COG2226	methyltransferase
SE95_RS07855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS07860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SE95_RS07885	COG0386	Belongs to the glutathione peroxidase family
SE95_RS07895	COG1132	(ABC) transporter
SE95_RS07900	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SE95_RS07910	COG1136	(ABC) transporter
SE95_RS07945	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SE95_RS07950	COG0667	Aldo Keto reductase
SE95_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS08000	COG4585	Histidine kinase
SE95_RS08025	COG0596	Alpha beta hydrolase
SE95_RS08035	COG1733	regulation of RNA biosynthetic process
SE95_RS08045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SE95_RS08070	COG0740	serine-type endopeptidase activity
SE95_RS08075	COG0740	serine-type endopeptidase activity
SE95_RS08095	COG2186	Transcriptional regulator
SE95_RS08110	COG2186	Transcriptional regulator
SE95_RS08130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SE95_RS08145	COG0483	inositol monophosphate 1-phosphatase activity
SE95_RS08270	COG0477	Major facilitator Superfamily
SE95_RS08280	COG2186	Transcriptional regulator
SE95_RS08295	COG0778	Nitroreductase
SE95_RS08305	COG4106	trans-aconitate 2-methyltransferase activity
SE95_RS08320	COG2197	response regulator
SE95_RS08350	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS08355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SE95_RS08355	COG0825	malonyl-CoA metabolic process
SE95_RS08365	COG0697	spore germination
SE95_RS08385	COG0492	ferredoxin-NADP+ reductase activity
SE95_RS08465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SE95_RS08465	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SE95_RS08475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SE95_RS08495	COG1716	ATPase activity
SE95_RS08515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SE95_RS08545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SE95_RS08555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SE95_RS08565	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SE95_RS08570	COG1177	transmembrane transport
SE95_RS08575	COG1176	ABC-type spermidine putrescine transport system, permease component I
SE95_RS08580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SE95_RS08585	COG3842	ATPase activity
SE95_RS08595	COG4977	sequence-specific DNA binding
SE95_RS08610	COG0596	Alpha beta hydrolase
SE95_RS08635	COG2146	nitrite reductase [NAD(P)H] activity
SE95_RS08660	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SE95_RS08680	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SE95_RS08685	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SE95_RS08690	COG1984	allophanate hydrolase subunit 2
SE95_RS08705	COG0438	transferase activity, transferring glycosyl groups
SE95_RS08750	COG0259	pyridoxamine-phosphate oxidase activity
SE95_RS08775	COG1024	Enoyl-CoA hydratase
SE95_RS08785	COG1605	Chorismate mutase
SE95_RS08805	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS08825	COG2070	2-Nitropropane dioxygenase
SE95_RS08840	COG0515	serine threonine protein kinase
SE95_RS08850	COG1960	acyl-CoA dehydrogenase activity
SE95_RS08870	COG2226	methyltransferase
SE95_RS08885	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SE95_RS08890	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SE95_RS08905	COG0456	acetyltransferase
SE95_RS08915	COG0587	DNA-directed DNA polymerase activity
SE95_RS08925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SE95_RS08925	COG0515	serine threonine protein kinase
SE95_RS08930	COG0596	Alpha beta hydrolase
SE95_RS08945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SE95_RS08950	COG2188	Transcriptional regulator
SE95_RS08955	COG0477	Major facilitator Superfamily
SE95_RS08970	COG2233	PERMEase
SE95_RS08985	COG1278	Cold shock
SE95_RS08995	COG2376	Dihydroxyacetone kinase
SE95_RS09000	COG1461	Dihydroxyacetone kinase
SE95_RS09025	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS09065	COG0395	ABC-type sugar transport system, permease component
SE95_RS09075	COG1793	dna ligase
SE95_RS09085	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SE95_RS09125	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS09145	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SE95_RS09150	COG0463	Glycosyl transferase, family 2
SE95_RS09165	COG0633	Ferredoxin
SE95_RS09165	COG3217	Mosc domain protein beta barrel domain protein
SE95_RS09185	COG0464	growth
SE95_RS09195	COG1349	DNA-binding transcription factor activity
SE95_RS09255	COG1940	carbohydrate kinase activity
SE95_RS09260	COG2223	nitrite transmembrane transporter activity
SE95_RS09270	COG2197	response regulator
SE95_RS09275	COG4585	Histidine kinase
SE95_RS09290	COG0445	tRNA wobble uridine modification
SE95_RS09300	COG0494	nUDIX hydrolase
SE95_RS09325	COG2318	DinB family
SE95_RS09330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SE95_RS09370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS09380	COG0584	glycerophosphoryl diester phosphodiesterase
SE95_RS09390	COG0765	amino acid transport
SE95_RS09395	COG1126	abc transporter atp-binding protein
SE95_RS09400	COG0456	acetyltransferase
SE95_RS09425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SE95_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS09435	COG0076	glutamate decarboxylase activity
SE95_RS09445	COG0477	Major facilitator Superfamily
SE95_RS09450	COG0154	amidase activity
SE95_RS09455	COG1309	transcriptional regulator
SE95_RS09475	COG4221	oxidoreductase activity
SE95_RS09480	COG1131	(ABC) transporter
SE95_RS09530	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SE95_RS09535	COG0179	Fumarylacetoacetate (FAA) hydrolase
SE95_RS09555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SE95_RS09560	COG0028	Belongs to the TPP enzyme family
SE95_RS09575	COG2192	nodulation
SE95_RS09590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SE95_RS09595	COG0148	phosphopyruvate hydratase activity
SE95_RS09630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SE95_RS09635	COG0140	phosphoribosyl-ATP diphosphatase activity
SE95_RS09640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SE95_RS09645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SE95_RS09645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SE95_RS09650	COG3201	nicotinamide mononucleotide transporter
SE95_RS09665	COG0702	epimerase
SE95_RS09670	COG1846	Transcriptional regulator
SE95_RS09670	COG1940	carbohydrate kinase activity
SE95_RS09675	COG0738	Major facilitator superfamily
SE95_RS09700	COG2233	PERMEase
SE95_RS09725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SE95_RS09735	COG0477	Major facilitator Superfamily
SE95_RS09750	COG0531	amino acid
SE95_RS09770	COG2390	Transcriptional regulator
SE95_RS09775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SE95_RS09790	COG3209	COG3209 Rhs family protein
SE95_RS09810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SE95_RS09825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SE95_RS09850	COG0284	orotidine-5'-phosphate decarboxylase activity
SE95_RS09855	COG0167	dihydroorotate dehydrogenase activity
SE95_RS09860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SE95_RS09865	COG0505	Belongs to the CarA family
SE95_RS09875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SE95_RS09880	COG0540	Belongs to the ATCase OTCase family
SE95_RS09885	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SE95_RS09895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SE95_RS09900	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SE95_RS09905	COG0006	proline dipeptidase activity
SE95_RS09915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SE95_RS09920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SE95_RS09925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SE95_RS09930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SE95_RS09935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SE95_RS09950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SE95_RS09955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SE95_RS09975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SE95_RS09995	COG0124	histidyl-tRNA synthetase
SE95_RS10005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SE95_RS10010	COG1196	nuclear chromosome segregation
SE95_RS10015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SE95_RS10020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SE95_RS10025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SE95_RS10030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SE95_RS10040	COG2255	four-way junction helicase activity
SE95_RS10045	COG0632	four-way junction helicase activity
SE95_RS10050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SE95_RS10055	COG0217	transcriptional regulatory protein
SE95_RS10060	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SE95_RS10065	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SE95_RS10080	COG0438	transferase activity, transferring glycosyl groups
SE95_RS10085	COG1560	Kdo2-lipid A biosynthetic process
SE95_RS10090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SE95_RS10120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SE95_RS10135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SE95_RS10185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SE95_RS10230	COG1648	precorrin-2 dehydrogenase activity
SE95_RS10230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SE95_RS10235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SE95_RS10250	COG1464	Belongs to the NlpA lipoprotein family
SE95_RS10255	COG2011	ABC-type metal ion transport system permease component
SE95_RS10280	COG0584	glycerophosphoryl diester phosphodiesterase
SE95_RS10295	COG0477	Major facilitator Superfamily
SE95_RS10305	COG0165	Argininosuccinate lyase
SE95_RS10310	COG0137	argininosuccinate synthase activity
SE95_RS10325	COG1438	arginine binding
SE95_RS10330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SE95_RS10335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SE95_RS10340	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SE95_RS10345	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SE95_RS10360	COG1091	dTDP-4-dehydrorhamnose reductase activity
SE95_RS10385	COG4106	trans-aconitate 2-methyltransferase activity
SE95_RS10405	COG0697	spore germination
SE95_RS10415	COG1649	PFAM Uncharacterised BCR, COG1649
SE95_RS10455	COG0072	phenylalanine-tRNA ligase activity
SE95_RS10455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SE95_RS10460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SE95_RS10465	COG5002	protein histidine kinase activity
SE95_RS10470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SE95_RS10475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SE95_RS10480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SE95_RS10485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SE95_RS10495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SE95_RS10505	COG1404	Belongs to the peptidase S8 family
SE95_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS10530	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS10535	COG0174	glutamine synthetase
SE95_RS10540	COG2186	Transcriptional regulator
SE95_RS10545	COG0531	amino acid
SE95_RS10550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SE95_RS10565	COG2233	PERMEase
SE95_RS10585	COG4176	ABC-type proline glycine betaine transport system permease component
SE95_RS10590	COG4175	Glycine betaine
SE95_RS10590	COG0517	IMP dehydrogenase activity
SE95_RS10595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SE95_RS10620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS10630	COG0805	protein transport
SE95_RS10635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SE95_RS10665	COG0544	peptidyl-prolyl cis-trans isomerase activity
SE95_RS10670	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SE95_RS10680	COG1609	Transcriptional regulator
SE95_RS10685	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SE95_RS10690	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SE95_RS10705	COG4122	O-methyltransferase activity
SE95_RS10710	COG1222	aaa ATPase
SE95_RS10735	COG0517	IMP dehydrogenase activity
SE95_RS10735	COG1994	Peptidase M50
SE95_RS10745	COG2197	response regulator
SE95_RS10750	COG4166	transmembrane transport
SE95_RS10755	COG0747	negative chemotaxis
SE95_RS10760	COG0546	phosphoglycolate phosphatase activity
SE95_RS10765	COG1410	methionine synthase
SE95_RS10765	COG0646	methionine synthase
SE95_RS10770	COG1414	Transcriptional regulator
SE95_RS10775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SE95_RS10780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SE95_RS10785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SE95_RS10790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS10795	COG2186	Transcriptional regulator
SE95_RS10800	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS10805	COG3618	amidohydrolase
SE95_RS10815	COG4211	Belongs to the binding-protein-dependent transport system permease family
SE95_RS10820	COG1129	ABC transporter
SE95_RS10830	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS10835	COG4948	Mandelate Racemase Muconate Lactonizing
SE95_RS10845	COG0215	cysteine-tRNA ligase activity
SE95_RS10865	COG0598	Magnesium transport protein CorA
SE95_RS10875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS10880	COG0667	Aldo Keto reductase
SE95_RS10910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SE95_RS10940	COG0745	RESPONSE REGULATOR receiver
SE95_RS10970	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SE95_RS10975	COG2149	membrane
SE95_RS10995	COG1960	acyl-CoA dehydrogenase activity
SE95_RS11005	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS11015	COG3876	Protein conserved in bacteria
SE95_RS11030	COG0477	Major facilitator Superfamily
SE95_RS11080	COG1960	acyl-CoA dehydrogenase activity
SE95_RS11105	COG1309	transcriptional regulator
SE95_RS11110	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SE95_RS11115	COG2188	Transcriptional regulator
SE95_RS11120	COG2814	Major facilitator Superfamily
SE95_RS11120	COG0477	Major facilitator Superfamily
SE95_RS11145	COG3619	membrane
SE95_RS11155	COG1834	amidinotransferase
SE95_RS11160	COG1725	Transcriptional regulator
SE95_RS11165	COG0367	asparagine synthase
SE95_RS11170	COG2226	methyltransferase
SE95_RS11180	COG0604	alcohol dehydrogenase
SE95_RS11180	COG3321	synthase
SE95_RS11180	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS11190	COG1522	sequence-specific DNA binding
SE95_RS11195	COG0531	amino acid
SE95_RS11205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SE95_RS11210	COG0587	DNA-directed DNA polymerase activity
SE95_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS11240	COG0330	HflC and HflK could
SE95_RS11255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS11260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS11265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SE95_RS11270	COG1126	abc transporter atp-binding protein
SE95_RS11275	COG0765	amino acid transport
SE95_RS11285	COG0765	amino acid transport
SE95_RS11315	COG2018	Roadblock/LC7 domain
SE95_RS11320	COG5002	protein histidine kinase activity
SE95_RS11325	COG1799	cell septum assembly
SE95_RS11330	COG1960	acyl-CoA dehydrogenase activity
SE95_RS11335	COG0477	Major facilitator Superfamily
SE95_RS11345	COG0671	phosphoesterase, PA-phosphatase related
SE95_RS11355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SE95_RS11365	COG0438	transferase activity, transferring glycosyl groups
SE95_RS11385	COG1160	GTP binding
SE95_RS11395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SE95_RS11420	COG1187	pseudouridine synthase activity
SE95_RS11425	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SE95_RS11430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SE95_RS11445	COG0686	Belongs to the AlaDH PNT family
SE95_RS11455	COG0494	nUDIX hydrolase
SE95_RS11460	COG0504	CTP synthase activity
SE95_RS11465	COG3387	PFAM Glycoside hydrolase 15-related
SE95_RS11480	COG0438	transferase activity, transferring glycosyl groups
SE95_RS11490	COG0497	DNA recombination
SE95_RS11500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SE95_RS11520	COG1120	ATPase activity
SE95_RS11525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS11530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS11545	COG0647	UMP catabolic process
SE95_RS11560	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SE95_RS11595	COG2094	Belongs to the DNA glycosylase MPG family
SE95_RS11605	COG1881	PFAM PEBP family protein
SE95_RS11630	COG1119	ATPase activity
SE95_RS11650	COG2197	response regulator
SE95_RS11655	COG4585	Histidine kinase
SE95_RS11665	COG5412	phage tail tape measure protein
SE95_RS11665	COG3953	SLT domain
SE95_RS11670	COG1131	(ABC) transporter
SE95_RS11670	COG0842	Transport permease protein
SE95_RS11670	COG1716	ATPase activity
SE95_RS11675	COG3830	Belongs to the UPF0237 family
SE95_RS11675	COG0560	Phosphoserine phosphatase
SE95_RS11695	COG2186	Transcriptional regulator
SE95_RS11700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SE95_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS11720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SE95_RS11735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SE95_RS11740	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SE95_RS11785	COG0300	oxidoreductase activity
SE95_RS11815	COG3387	PFAM Glycoside hydrolase 15-related
SE95_RS11845	COG1302	Protein conserved in bacteria
SE95_RS11855	COG1024	Enoyl-CoA hydratase
SE95_RS11865	COG0488	(ABC) transporter
SE95_RS11880	COG0235	Class ii aldolase
SE95_RS11900	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SE95_RS11905	COG1492	cobalamin metabolic process
SE95_RS11920	COG1797	cobyrinic acid a,c-diamide synthase activity
SE95_RS11945	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS11955	COG0640	Transcriptional regulator
SE95_RS11970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SE95_RS11975	COG1917	Cupin 2, conserved barrel domain protein
SE95_RS11980	COG5285	phytanoyl-CoA dioxygenase
SE95_RS11985	COG1902	pentaerythritol trinitrate reductase activity
SE95_RS12000	COG2226	methyltransferase
SE95_RS12015	COG1414	Transcriptional regulator
SE95_RS12035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SE95_RS12040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SE95_RS12045	COG2261	transglycosylase associated protein
SE95_RS12055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS12060	COG2226	methyltransferase
SE95_RS12080	COG2171	N-acyltransferase activity
SE95_RS12085	COG3226	Transcriptional regulator
SE95_RS12090	COG2076	Multidrug Resistance protein
SE95_RS12100	COG0822	iron-sulfur transferase activity
SE95_RS12105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SE95_RS12110	COG0396	ATPase activity
SE95_RS12120	COG0719	Fe-S assembly protein
SE95_RS12135	COG1131	(ABC) transporter
SE95_RS12160	COG0109	protoheme IX farnesyltransferase activity
SE95_RS12165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SE95_RS12170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SE95_RS12185	COG0363	glucosamine-6-phosphate deaminase activity
SE95_RS12190	COG0166	Belongs to the GPI family
SE95_RS12205	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SE95_RS12210	COG0149	triose-phosphate isomerase activity
SE95_RS12215	COG0126	phosphoglycerate kinase activity
SE95_RS12220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SE95_RS12225	COG1481	regulation of sporulation
SE95_RS12230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SE95_RS12235	COG1660	Displays ATPase and GTPase activities
SE95_RS12240	COG0322	excinuclease ABC activity
SE95_RS12265	COG2814	Major facilitator Superfamily
SE95_RS12270	COG1063	alcohol dehydrogenase
SE95_RS12275	COG1609	Transcriptional regulator
SE95_RS12285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SE95_RS12295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SE95_RS12325	COG0556	nucleotide-excision repair
SE95_RS12330	COG0584	glycerophosphoryl diester phosphodiesterase
SE95_RS12400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SE95_RS12420	COG0237	dephospho-CoA kinase activity
SE95_RS12445	COG1643	Atp-dependent helicase
SE95_RS12480	COG2050	protein possibly involved in aromatic compounds catabolism
SE95_RS12490	COG0559	Belongs to the binding-protein-dependent transport system permease family
SE95_RS12535	COG0737	Belongs to the 5'-nucleotidase family
SE95_RS12570	COG0366	Alpha amylase catalytic
SE95_RS12570	COG1470	cell adhesion involved in biofilm formation
SE95_RS12580	COG2197	response regulator
SE95_RS12610	COG2267	carboxylic ester hydrolase activity
SE95_RS12630	COG3467	pyridoxamine 5'-phosphate
SE95_RS12645	COG0640	Transcriptional regulator
SE95_RS12660	COG0067	glutamate synthase
SE95_RS12660	COG0069	glutamate synthase activity
SE95_RS12660	COG0070	glutamate synthase
SE95_RS12675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SE95_RS12685	COG0159	tryptophan synthase activity
SE95_RS12690	COG0133	tryptophan synthase activity
SE95_RS12695	COG0134	indole-3-glycerol-phosphate synthase activity
SE95_RS12720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SE95_RS12730	COG0583	DNA-binding transcription factor activity
SE95_RS12740	COG1053	succinate dehydrogenase
SE95_RS12745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SE95_RS12750	COG0107	imidazoleglycerol-phosphate synthase activity
SE95_RS12755	COG0251	oxidation-reduction process
SE95_RS12760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SE95_RS12765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SE95_RS12770	COG0131	Imidazoleglycerol-phosphate dehydratase
SE95_RS12775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SE95_RS12780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SE95_RS12795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SE95_RS12815	COG1432	Conserved Protein
SE95_RS12820	COG0587	DNA-directed DNA polymerase activity
SE95_RS12870	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SE95_RS12880	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SE95_RS12885	COG3599	regulation of cell shape
SE95_RS12895	COG1799	cell septum assembly
SE95_RS12900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SE95_RS12910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SE95_RS12915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SE95_RS12920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SE95_RS12930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SE95_RS12935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SE95_RS12945	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SE95_RS12950	COG0768	penicillin binding
SE95_RS12960	COG0275	rRNA processing
SE95_RS12970	COG0714	Associated with various cellular activities
SE95_RS12990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SE95_RS13000	COG1716	ATPase activity
SE95_RS13000	COG0842	Transport permease protein
SE95_RS13000	COG1131	(ABC) transporter
SE95_RS13010	COG1309	transcriptional regulator
SE95_RS13020	COG1233	COG1233 Phytoene dehydrogenase and related
SE95_RS13035	COG0352	thiamine-phosphate diphosphorylase activity
SE95_RS13050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SE95_RS13050	COG2022	thiamine diphosphate biosynthetic process
SE95_RS13060	COG2022	thiamine diphosphate biosynthetic process
SE95_RS13065	COG0789	Transcriptional regulator
SE95_RS13070	COG2815	serine threonine protein kinase
SE95_RS13070	COG0515	serine threonine protein kinase
SE95_RS13075	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SE95_RS13080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SE95_RS13085	COG2193	ferroxidase activity
SE95_RS13090	COG0243	molybdopterin cofactor binding
SE95_RS13095	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SE95_RS13105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SE95_RS13110	COG0205	6-phosphofructokinase activity
SE95_RS13115	COG2197	response regulator
SE95_RS13145	COG1940	carbohydrate kinase activity
SE95_RS13155	COG0003	Pfam Anion-transporting ATPase
SE95_RS13175	COG0438	transferase activity, transferring glycosyl groups
SE95_RS13190	COG0791	NLP P60 protein
SE95_RS13220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SE95_RS13225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SE95_RS13230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SE95_RS13235	COG0723	plastoquinol--plastocyanin reductase activity
SE95_RS13240	COG2010	Cytochrome c
SE95_RS13245	COG1845	cytochrome c oxidase, subunit III
SE95_RS13255	COG1376	ErfK ybiS ycfS ynhG family protein
SE95_RS13265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SE95_RS13270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SE95_RS13280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SE95_RS13295	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SE95_RS13325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SE95_RS13330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SE95_RS13335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SE95_RS13340	COG2197	response regulator
SE95_RS13345	COG4585	Histidine kinase
SE95_RS13380	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SE95_RS13390	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SE95_RS13395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SE95_RS13405	COG0508	dehydrogenase complex catalyzes the overall conversion of
SE95_RS13415	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SE95_RS13455	COG0321	lipoyl(octanoyl) transferase activity
SE95_RS13460	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SE95_RS13495	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS13515	COG0745	RESPONSE REGULATOR receiver
SE95_RS13535	COG2197	response regulator
SE95_RS13580	COG0366	Alpha amylase catalytic
SE95_RS13585	COG3833	ABC-type maltose transport systems, permease component
SE95_RS13590	COG1175	transmembrane transport
SE95_RS13595	COG2182	Extracellular solute-binding protein
SE95_RS13600	COG0366	Alpha amylase catalytic
SE95_RS13605	COG1609	Transcriptional regulator
SE95_RS13615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SE95_RS13630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SE95_RS13635	COG0174	glutamine synthetase
SE95_RS13640	COG2267	carboxylic ester hydrolase activity
SE95_RS13650	COG2132	Multicopper oxidase
SE95_RS13655	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SE95_RS13655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SE95_RS13660	COG2814	Major facilitator Superfamily
SE95_RS13670	COG1309	transcriptional regulator
SE95_RS13675	COG0477	Major facilitator Superfamily
SE95_RS13680	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SE95_RS13720	COG1994	Peptidase M50
SE95_RS13740	COG1175	transmembrane transport
SE95_RS13750	COG2186	Transcriptional regulator
SE95_RS13755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SE95_RS13775	COG5398	heme oxygenase
SE95_RS13805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SE95_RS13810	COG2814	Major facilitator Superfamily
SE95_RS13815	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS13910	COG0789	Transcriptional regulator
SE95_RS13925	COG3022	response to hydroperoxide
SE95_RS13930	COG0800	Aldolase
SE95_RS13945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SE95_RS13950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SE95_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS13970	COG2030	dehydratase
SE95_RS13975	COG4585	Histidine kinase
SE95_RS13980	COG2197	response regulator
SE95_RS13990	COG0183	Belongs to the thiolase family
SE95_RS13995	COG1960	acyl-CoA dehydrogenase activity
SE95_RS14015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS14040	COG0438	transferase activity, transferring glycosyl groups
SE95_RS14045	COG1309	transcriptional regulator
SE95_RS14080	COG3845	ABC transporter
SE95_RS14090	COG0183	Belongs to the thiolase family
SE95_RS14095	COG2124	cytochrome p450
SE95_RS14105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SE95_RS14225	COG1072	(Pantothenic acid kinase))
SE95_RS14250	COG2259	Doxx family
SE95_RS14280	COG2186	Transcriptional regulator
SE95_RS14300	COG1358	cellular component organization or biogenesis
SE95_RS14350	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SE95_RS14360	COG0477	Major facilitator Superfamily
SE95_RS14365	COG1309	transcriptional regulator
SE95_RS14380	COG4585	Histidine kinase
SE95_RS14385	COG2197	response regulator
SE95_RS14400	COG0667	Aldo Keto reductase
SE95_RS14405	COG0789	Transcriptional regulator
SE95_RS14430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SE95_RS14435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS14440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SE95_RS14470	COG1309	transcriptional regulator
SE95_RS14480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SE95_RS14490	COG1172	Belongs to the binding-protein-dependent transport system permease family
SE95_RS14495	COG1129	ABC transporter
SE95_RS14500	COG1609	Transcriptional regulator
SE95_RS14505	COG1764	response to oxidative stress
SE95_RS14510	COG2130	NADP-dependent
SE95_RS14520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SE95_RS14545	COG0500	methyltransferase
SE95_RS14550	COG4981	capsule polysaccharide biosynthetic process
SE95_RS14590	COG1077	Cell shape determining protein MreB Mrl
SE95_RS14595	COG0588	phosphoglycerate mutase activity
SE95_RS14600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SE95_RS14635	COG1070	Carbohydrate kinase
SE95_RS14645	COG0358	DNA primase activity
SE95_RS14660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SE95_RS14670	COG0243	molybdopterin cofactor binding
SE95_RS14675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SE95_RS14705	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SE95_RS14735	COG0667	Aldo Keto reductase
SE95_RS14755	COG1473	amidohydrolase
SE95_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS14770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SE95_RS14775	COG2146	nitrite reductase [NAD(P)H] activity
SE95_RS14775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SE95_RS14790	COG0531	amino acid
SE95_RS14800	COG1175	transmembrane transport
SE95_RS14805	COG0395	ABC-type sugar transport system, permease component
SE95_RS14810	COG2175	clavaminate synthase activity
SE95_RS14840	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SE95_RS14845	COG0574	Belongs to the PEP-utilizing enzyme family
SE95_RS14845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SE95_RS14875	COG0477	Major facilitator Superfamily
SE95_RS14880	COG0667	Aldo Keto reductase
SE95_RS14890	COG0423	glycine-tRNA ligase activity
SE95_RS14900	COG1121	(ABC) transporter
SE95_RS14905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SE95_RS14925	COG1228	amidohydrolase
SE95_RS14930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SE95_RS14935	COG1381	Involved in DNA repair and RecF pathway recombination
SE95_RS14975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SE95_RS14995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SE95_RS15010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SE95_RS15025	COG1486	melibiose metabolic process
SE95_RS15040	COG4948	Mandelate Racemase Muconate Lactonizing
SE95_RS15050	COG1234	tRNA 3'-trailer cleavage
SE95_RS15055	COG0537	adenosine 5'-monophosphoramidase activity
SE95_RS15080	COG0484	heat shock protein binding
SE95_RS15085	COG1420	regulation of RNA biosynthetic process
SE95_RS15115	COG1022	Amp-dependent synthetase and ligase
SE95_RS15120	COG0481	GTPase activity
SE95_RS15125	COG0268	Binds directly to 16S ribosomal RNA
SE95_RS15155	COG1555	photosystem II stabilization
SE95_RS15160	COG1307	EDD domain protein, DegV family
SE95_RS15170	COG0495	leucyl-tRNA aminoacylation
SE95_RS15200	COG0588	phosphoglycerate mutase activity
SE95_RS15205	COG0799	negative regulation of ribosome biogenesis
SE95_RS15215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SE95_RS15220	COG0501	Belongs to the peptidase M48B family
SE95_RS15235	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SE95_RS15245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SE95_RS15255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SE95_RS15260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SE95_RS15265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SE95_RS15270	COG1530	ribonuclease E activity
SE95_RS15300	COG0772	Belongs to the SEDS family
SE95_RS15305	COG0768	penicillin binding
SE95_RS15320	COG1077	Cell shape determining protein MreB Mrl
SE95_RS15325	COG0105	UTP biosynthetic process
SE95_RS15335	COG0285	dihydrofolate synthase activity
SE95_RS15340	COG0768	penicillin binding
SE95_RS15350	COG0525	valine-tRNA ligase activity
SE95_RS15360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SE95_RS15365	COG0740	serine-type endopeptidase activity
SE95_RS15370	COG0740	serine-type endopeptidase activity
SE95_RS15375	COG0544	peptidyl-prolyl cis-trans isomerase activity
SE95_RS15400	COG0475	glutathione-regulated potassium exporter activity
SE95_RS15410	COG4552	Acetyltransferase involved in intracellular survival and related
SE95_RS15420	COG0698	ribose 5-phosphate isomerase
SE95_RS15425	COG1113	amino acid transport
SE95_RS15435	COG1113	amino acid transport
SE95_RS15440	COG1113	amino acid transport
SE95_RS15445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SE95_RS15450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SE95_RS15480	COG4266	Belongs to the allantoicase family
SE95_RS15525	COG0668	transmembrane transport
SE95_RS15535	COG1846	Transcriptional regulator
SE95_RS15535	COG1940	carbohydrate kinase activity
SE95_RS15545	COG1175	transmembrane transport
SE95_RS15550	COG0395	ABC-type sugar transport system, permease component
SE95_RS15575	COG2188	Transcriptional regulator
SE95_RS15585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SE95_RS15615	COG2346	COG2346, Truncated hemoglobins
SE95_RS15645	COG0629	single-stranded DNA binding
SE95_RS15675	COG2391	methyltransferase activity
SE95_RS15690	COG2815	serine threonine protein kinase
SE95_RS15690	COG0515	serine threonine protein kinase
SE95_RS15700	COG1077	Cell shape determining protein MreB Mrl
SE95_RS15710	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SE95_RS15725	COG1131	(ABC) transporter
SE95_RS15740	COG3962	Belongs to the TPP enzyme family
SE95_RS15745	COG3718	enzyme involved in inositol metabolism
SE95_RS15755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SE95_RS15765	COG0673	inositol 2-dehydrogenase activity
SE95_RS15770	COG2814	Major facilitator Superfamily
SE95_RS15790	COG0673	inositol 2-dehydrogenase activity
SE95_RS15805	COG2608	mercury ion transmembrane transporter activity
SE95_RS15815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SE95_RS15830	COG0673	inositol 2-dehydrogenase activity
SE95_RS15835	COG1609	Transcriptional regulator
SE95_RS15845	COG1472	Belongs to the glycosyl hydrolase 3 family
SE95_RS15865	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SE95_RS15880	COG0028	Belongs to the TPP enzyme family
SE95_RS15925	COG1946	Acyl-CoA thioesterase
SE95_RS15935	COG1309	transcriptional regulator
SE95_RS15940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SE95_RS15955	COG1960	acyl-CoA dehydrogenase activity
SE95_RS15970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SE95_RS15975	COG0589	response to stress
SE95_RS15980	COG4977	sequence-specific DNA binding
SE95_RS15985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SE95_RS15995	COG2910	NAD(P)H-binding
SE95_RS16005	COG3979	chitinase
SE95_RS16040	COG0297	glycogen (starch) synthase activity
SE95_RS16045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SE95_RS16050	COG0438	transferase activity, transferring glycosyl groups
SE95_RS16110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS16130	COG0154	amidase activity
SE95_RS16145	COG0765	amino acid transport
SE95_RS16150	COG0765	amino acid transport
SE95_RS16155	COG1126	abc transporter atp-binding protein
SE95_RS16170	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS16175	COG3397	chitin binding
SE95_RS16180	COG2318	DinB family
SE95_RS16240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SE95_RS16245	COG2188	Transcriptional regulator
SE95_RS16260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SE95_RS16270	COG3764	Sortase (surface protein transpeptidase)
SE95_RS16275	COG2733	membrane
SE95_RS16305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SE95_RS16315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SE95_RS16330	COG2205	protein histidine kinase activity
SE95_RS16360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SE95_RS16370	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SE95_RS16375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SE95_RS16380	COG1263	PTS System
SE95_RS16385	COG1263	PTS System
SE95_RS16390	COG1234	tRNA 3'-trailer cleavage
SE95_RS16415	COG1113	amino acid transport
SE95_RS16425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SE95_RS16435	COG1335	isochorismatase
SE95_RS16470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SE95_RS16475	COG0222	ribosome binding
SE95_RS16480	COG0494	nUDIX hydrolase
SE95_RS16510	COG0277	FAD linked oxidase domain protein
SE95_RS16515	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SE95_RS16525	COG1174	glycine betaine transport
SE95_RS16580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SE95_RS16595	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SE95_RS16605	COG2814	Major facilitator Superfamily
SE95_RS16610	COG0583	DNA-binding transcription factor activity
SE95_RS16620	COG1678	Uncharacterized ACR, COG1678
SE95_RS16625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SE95_RS16630	COG0776	regulation of translation
SE95_RS16640	COG3973	AAA domain
SE95_RS16665	COG2223	nitrite transmembrane transporter activity
SE95_RS16680	COG0583	DNA-binding transcription factor activity
SE95_RS16695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SE95_RS16700	COG0793	Belongs to the peptidase S41A family
SE95_RS16705	COG2177	Part of the ABC transporter FtsEX involved in
SE95_RS16710	COG2884	Cell division ATP-binding protein ftsE
SE95_RS16720	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SE95_RS16725	COG0515	serine threonine protein kinase
SE95_RS16730	COG0515	serine threonine protein kinase
SE95_RS16745	COG1653	transport
SE95_RS16750	COG1175	transmembrane transport
SE95_RS16755	COG0395	ABC-type sugar transport system, permease component
SE95_RS16770	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SE95_RS16805	COG0463	Glycosyl transferase, family 2
SE95_RS16825	COG1309	transcriptional regulator
SE95_RS16835	COG1134	teichoic acid transport
SE95_RS16835	COG1388	LysM domain
SE95_RS16840	COG2902	Dehydrogenase
SE95_RS16845	COG0546	phosphoglycolate phosphatase activity
SE95_RS16860	COG0653	protein targeting
SE95_RS16870	COG3214	Protein conserved in bacteria
SE95_RS16875	COG2197	response regulator
SE95_RS16880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SE95_RS16890	COG0823	Involved in the tonB-independent uptake of proteins
SE95_RS16895	COG5000	phosphorelay sensor kinase activity
SE95_RS16895	COG5002	protein histidine kinase activity
SE95_RS16900	COG0745	RESPONSE REGULATOR receiver
SE95_RS16905	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SE95_RS16925	COG0714	Associated with various cellular activities
SE95_RS16970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SE95_RS16980	COG1482	cell wall glycoprotein biosynthetic process
SE95_RS16990	COG2835	tetraacyldisaccharide 4'-kinase activity
SE95_RS16995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SE95_RS17030	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SE95_RS17035	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SE95_RS17035	COG0778	Nitroreductase
SE95_RS17070	COG1316	TRANSCRIPTIONal
SE95_RS17080	COG1316	TRANSCRIPTIONal
SE95_RS17100	COG1316	TRANSCRIPTIONal
SE95_RS17120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SE95_RS17170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SE95_RS17200	COG2205	protein histidine kinase activity
SE95_RS17205	COG0745	RESPONSE REGULATOR receiver
SE95_RS17210	COG3104	oligopeptide transport
SE95_RS17240	COG1366	Belongs to the anti-sigma-factor antagonist family
SE95_RS17245	COG1191	sigma factor activity
SE95_RS17250	COG1228	amidohydrolase
SE95_RS17260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SE95_RS17265	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SE95_RS17280	COG1131	(ABC) transporter
SE95_RS17305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SE95_RS17320	COG2755	lipolytic protein G-D-S-L family
SE95_RS17325	COG0183	Belongs to the thiolase family
SE95_RS17350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SE95_RS17365	COG1136	(ABC) transporter
SE95_RS17365	COG0577	efflux transmembrane transporter activity
SE95_RS17370	COG1136	(ABC) transporter
SE95_RS17370	COG0577	efflux transmembrane transporter activity
SE95_RS17375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SE95_RS17400	COG0148	phosphopyruvate hydratase activity
SE95_RS17415	COG2124	cytochrome p450
SE95_RS17425	COG2814	Major facilitator Superfamily
SE95_RS17460	COG2815	serine threonine protein kinase
SE95_RS17460	COG0515	serine threonine protein kinase
SE95_RS17495	COG2814	Major facilitator Superfamily
SE95_RS17525	COG4585	Histidine kinase
SE95_RS17535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SE95_RS17540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SE95_RS17545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SE95_RS17550	COG0193	aminoacyl-tRNA hydrolase activity
SE95_RS17560	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SE95_RS17570	COG1309	transcriptional regulator
SE95_RS17575	COG4106	trans-aconitate 2-methyltransferase activity
SE95_RS17595	COG2197	response regulator
SE95_RS17600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SE95_RS17630	COG0488	(ABC) transporter
SE95_RS17665	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SE95_RS17670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SE95_RS17675	COG3584	3D domain protein
SE95_RS17675	COG3583	domain protein
SE95_RS17680	COG0084	hydrolase, TatD family'
SE95_RS17705	COG0442	prolyl-tRNA aminoacylation
SE95_RS17725	COG1122	ATPase activity
SE95_RS17735	COG0310	cobalt ion transport
SE95_RS17745	COG4946	Tricorn protease homolog
SE95_RS17745	COG0793	Belongs to the peptidase S41A family
SE95_RS17750	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS17760	COG2072	flavoprotein involved in K transport
SE95_RS17765	COG0789	Transcriptional regulator
SE95_RS17770	COG0708	Exodeoxyribonuclease III
SE95_RS17775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SE95_RS17815	COG1131	(ABC) transporter
SE95_RS17825	COG1725	Transcriptional regulator
SE95_RS17830	COG2205	protein histidine kinase activity
SE95_RS17840	COG0789	Transcriptional regulator
SE95_RS17845	COG1819	glycosyl
SE95_RS17865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SE95_RS17870	COG0521	Mo-molybdopterin cofactor biosynthetic process
SE95_RS17870	COG0315	cyclic pyranopterin monophosphate synthase activity
SE95_RS17875	COG0315	cyclic pyranopterin monophosphate synthase activity
SE95_RS17885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SE95_RS17890	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SE95_RS17900	COG3263	regulation of cellular component size
SE95_RS17915	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SE95_RS17925	COG1970	mechanosensitive ion channel activity
SE95_RS17935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SE95_RS17940	COG0477	Major facilitator Superfamily
SE95_RS17945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SE95_RS17950	COG2188	Transcriptional regulator
SE95_RS17955	COG0730	response to heat
SE95_RS17990	COG3191	aminopeptidase activity
SE95_RS18010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SE95_RS18020	COG2084	Dehydrogenase
SE95_RS18030	COG1105	Belongs to the carbohydrate kinase PfkB family
SE95_RS18035	COG1349	DNA-binding transcription factor activity
SE95_RS18045	COG1247	-acetyltransferase
SE95_RS18070	COG1846	Transcriptional regulator
SE95_RS18090	COG1309	transcriptional regulator
SE95_RS18135	COG0514	ATP-dependent DNA helicase (RecQ)
SE95_RS18140	COG2205	protein histidine kinase activity
SE95_RS18160	COG0640	Transcriptional regulator
SE95_RS18170	COG1686	Belongs to the peptidase S11 family
SE95_RS18195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SE95_RS18200	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS18215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SE95_RS18225	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SE95_RS18340	COG1024	Enoyl-CoA hydratase
SE95_RS18355	COG0515	serine threonine protein kinase
SE95_RS18355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SE95_RS18360	COG1309	transcriptional regulator
SE95_RS18370	COG1960	acyl-CoA dehydrogenase activity
SE95_RS18400	COG1024	Enoyl-CoA hydratase
SE95_RS18415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SE95_RS18420	COG2271	Major facilitator Superfamily
SE95_RS18430	COG1960	acyl-CoA dehydrogenase activity
SE95_RS18435	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS18450	COG1960	acyl-CoA dehydrogenase activity
SE95_RS18455	COG1960	acyl-CoA dehydrogenase activity
SE95_RS18460	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS18485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SE95_RS18495	COG0516	GMP reductase activity
SE95_RS18505	COG1595	DNA-templated transcription, initiation
SE95_RS18520	COG0583	DNA-binding transcription factor activity
SE95_RS18530	COG4221	oxidoreductase activity
SE95_RS18540	COG0459	protein refolding
SE95_RS18545	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SE95_RS18550	COG0772	Belongs to the SEDS family
SE95_RS18565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SE95_RS18590	COG0802	atpase or kinase
SE95_RS18600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SE95_RS18610	COG0736	holo-[acyl-carrier-protein] synthase activity
SE95_RS18615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SE95_RS18625	COG1072	(Pantothenic acid kinase))
SE95_RS18630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SE95_RS18635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SE95_RS18640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SE95_RS18650	COG0101	tRNA pseudouridine synthase activity
SE95_RS18655	COG0203	ribosomal protein L17
SE95_RS18660	COG0202	RNA polymerase activity
SE95_RS18665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SE95_RS18670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SE95_RS18675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SE95_RS18680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SE95_RS18685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SE95_RS18695	COG0563	adenylate kinase activity
SE95_RS18705	COG0200	Binds to the 23S rRNA
SE95_RS18710	COG1841	ribosomal large subunit assembly
SE95_RS18715	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SE95_RS18720	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SE95_RS18725	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SE95_RS18730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SE95_RS18740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SE95_RS18745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SE95_RS18750	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SE95_RS18755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SE95_RS18760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SE95_RS18765	COG0255	Belongs to the universal ribosomal protein uL29 family
SE95_RS18770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SE95_RS18775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SE95_RS18780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SE95_RS18785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SE95_RS18790	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SE95_RS18795	COG0089	rRNA binding
SE95_RS18800	COG0088	Forms part of the polypeptide exit tunnel
SE95_RS18805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SE95_RS18810	COG0051	transcription antitermination factor activity, RNA binding
SE95_RS18815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SE95_RS18820	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SE95_RS18825	COG0049	tRNA binding
SE95_RS18830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SE95_RS18840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SE95_RS18845	COG0085	RNA polymerase activity
SE95_RS18855	COG0222	ribosome binding
SE95_RS18860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SE95_RS18870	COG0081	regulation of translation
SE95_RS18875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SE95_RS18880	COG0250	Participates in transcription elongation, termination and antitermination
SE95_RS18895	COG0436	Aminotransferase
SE95_RS18900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SE95_RS18905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SE95_RS18915	COG2030	dehydratase
SE95_RS18920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SE95_RS18950	COG1666	GTP binding
SE95_RS18955	COG3304	Inner membrane component domain
SE95_RS18960	COG0501	Belongs to the peptidase M48B family
SE95_RS18965	COG1007	ATP synthesis coupled electron transport
SE95_RS18975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SE95_RS18980	COG0713	ATP synthesis coupled electron transport
SE95_RS18985	COG0839	Belongs to the complex I subunit 6 family
SE95_RS18990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SE95_RS18995	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SE95_RS19000	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SE95_RS19005	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SE95_RS19010	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SE95_RS19025	COG4585	Histidine kinase
SE95_RS19030	COG4585	Histidine kinase
SE95_RS19040	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SE95_RS19040	COG0674	pyruvate-flavodoxin oxidoreductase activity
SE95_RS19045	COG1013	pyruvate-flavodoxin oxidoreductase activity
SE95_RS19070	COG0142	geranyltranstransferase activity
SE95_RS19090	COG1007	ATP synthesis coupled electron transport
SE95_RS19100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SE95_RS19105	COG0713	ATP synthesis coupled electron transport
SE95_RS19110	COG0839	Belongs to the complex I subunit 6 family
SE95_RS19115	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SE95_RS19120	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SE95_RS19125	COG1034	ATP synthesis coupled electron transport
SE95_RS19130	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SE95_RS19140	COG0649	NAD binding
SE95_RS19145	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SE95_RS19150	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SE95_RS19175	COG2226	methyltransferase
SE95_RS19185	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SE95_RS19195	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SE95_RS19200	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SE95_RS19205	COG1278	Cold shock
SE95_RS19220	COG1309	transcriptional regulator
SE95_RS19230	COG1301	dicarboxylic acid transport
SE95_RS19245	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SE95_RS19270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SE95_RS19275	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SE95_RS19335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SE95_RS19340	COG1333	cytochrome c biogenesis protein
SE95_RS19345	COG0785	Cytochrome C biogenesis protein
SE95_RS19360	COG0406	alpha-ribazole phosphatase activity
SE95_RS19365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SE95_RS19395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SE95_RS19400	COG1742	UPF0060 membrane protein
SE95_RS19415	COG1690	Belongs to the RtcB family
SE95_RS19440	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SE95_RS19445	COG0018	arginyl-trna synthetase
SE95_RS19465	COG0113	porphobilinogen synthase activity
SE95_RS19470	COG1648	precorrin-2 dehydrogenase activity
SE95_RS19470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SE95_RS19475	COG0181	hydroxymethylbilane synthase activity
SE95_RS19480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SE95_RS19485	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SE95_RS19535	COG0123	including yeast histone deacetylase and acetoin utilization protein
SE95_RS19545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SE95_RS19570	COG1846	Transcriptional regulator
SE95_RS19585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SE95_RS19610	COG0579	oxidoreductase
SE95_RS19615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SE95_RS19655	COG0513	Belongs to the DEAD box helicase family
SE95_RS19730	COG1643	Atp-dependent helicase
SE95_RS19765	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SE95_RS19780	COG3119	arylsulfatase activity
SE95_RS19800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SE95_RS19805	COG0047	phosphoribosylformylglycinamidine synthase activity
SE95_RS19810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SE95_RS19835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SE95_RS19840	COG2814	Major facilitator Superfamily
SE95_RS19845	COG0583	DNA-binding transcription factor activity
SE95_RS19860	COG0151	Belongs to the GarS family
SE95_RS19875	COG1802	Transcriptional regulator
SE95_RS19880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SE95_RS19890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SE95_RS19890	COG0515	serine threonine protein kinase
SE95_RS19895	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SE95_RS19910	COG1131	(ABC) transporter
SE95_RS19915	COG3559	Exporter of polyketide antibiotics
SE95_RS19920	COG2197	response regulator
SE95_RS19925	COG4585	Histidine kinase
SE95_RS19935	COG3844	kynureninase activity
SE95_RS19950	COG0477	Major facilitator Superfamily
SE95_RS19955	COG0191	fructose-bisphosphate aldolase activity
SE95_RS19960	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SE95_RS19975	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SE95_RS20005	COG0542	response to heat
SE95_RS20025	COG0789	Transcriptional regulator
SE95_RS20030	COG0484	heat shock protein binding
SE95_RS20035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SE95_RS20040	COG0443	Heat shock 70 kDa protein
SE95_RS20045	COG2181	nitrate reductase activity
SE95_RS20045	COG0247	lactate metabolic process
SE95_RS20055	COG2755	lipolytic protein G-D-S-L family
SE95_RS20065	COG0717	Belongs to the dCTP deaminase family
SE95_RS20095	COG1674	ftsk spoiiie
SE95_RS20115	COG2301	Belongs to the HpcH HpaI aldolase family
SE95_RS20120	COG2301	Belongs to the HpcH HpaI aldolase family
SE95_RS20145	COG3629	intracellular signal transduction
SE95_RS20145	COG3903	Transcriptional regulator
SE95_RS20210	COG1316	TRANSCRIPTIONal
SE95_RS20255	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SE95_RS20275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SE95_RS20305	COG1174	glycine betaine transport
SE95_RS20310	COG1174	glycine betaine transport
SE95_RS20335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SE95_RS20340	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SE95_RS20365	COG1960	acyl-CoA dehydrogenase activity
SE95_RS20370	COG1362	aminopeptidase activity
SE95_RS20375	COG3903	Transcriptional regulator
SE95_RS20375	COG3629	intracellular signal transduction
SE95_RS20415	COG2814	Major facilitator Superfamily
SE95_RS20425	COG0494	nUDIX hydrolase
SE95_RS20430	COG0508	dehydrogenase complex catalyzes the overall conversion of
SE95_RS20435	COG0022	dehydrogenase e1 component
SE95_RS20460	COG0515	serine threonine protein kinase
SE95_RS20465	COG0515	serine threonine protein kinase
SE95_RS20485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SE95_RS20495	COG0746	molybdenum cofactor guanylyltransferase activity
SE95_RS20515	COG1522	sequence-specific DNA binding
SE95_RS20520	COG1309	transcriptional regulator
SE95_RS20525	COG1250	3-hydroxyacyl-CoA dehydrogenase
SE95_RS20550	COG3396	Phenylacetate-CoA oxygenase
SE95_RS20555	COG3460	Phenylacetate-CoA oxygenase
SE95_RS20560	COG3396	Phenylacetate-CoA oxygenase
SE95_RS20565	COG2151	metal-sulfur cluster biosynthetic enzyme
SE95_RS20570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SE95_RS20610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SE95_RS20620	COG0583	DNA-binding transcription factor activity
SE95_RS20630	COG1716	ATPase activity
SE95_RS20635	COG1716	ATPase activity
SE95_RS20650	COG0768	penicillin binding
SE95_RS20660	COG0515	serine threonine protein kinase
SE95_RS20665	COG3764	Sortase (surface protein transpeptidase)
SE95_RS20670	COG3764	Sortase (surface protein transpeptidase)
SE95_RS20680	COG3764	Sortase (surface protein transpeptidase)
SE95_RS20695	COG0705	Rhomboid family
SE95_RS20750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SE95_RS20755	COG0187	DNA topoisomerase II activity
SE95_RS20760	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SE95_RS20765	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SE95_RS20770	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SE95_RS20775	COG0592	DNA-directed DNA polymerase activity
SE95_RS20790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SE95_RS20795	COG0594	ribonuclease P activity
SE95_RS20800	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SE95_RS20805	COG0706	membrane insertase activity
SE95_RS20815	COG0357	Ribosomal RNA small subunit methyltransferase G
SE95_RS20820	COG1192	Involved in chromosome partitioning
SE95_RS20835	COG3118	belongs to the thioredoxin family
SE95_RS20840	COG0492	ferredoxin-NADP+ reductase activity
SE95_RS20850	COG1595	DNA-templated transcription, initiation
SE95_RS20855	COG0515	serine threonine protein kinase
SE95_RS20855	COG2815	serine threonine protein kinase
SE95_RS20870	COG0617	tRNA 3'-terminal CCA addition
SE95_RS20885	COG1260	myo-inositol-1-phosphate synthase
SE95_RS20895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SE95_RS20895	COG4499	WXG100 protein secretion system (Wss), protein YukC
SE95_RS20920	COG0360	Binds together with S18 to 16S ribosomal RNA
SE95_RS20925	COG0629	single-stranded DNA binding
SE95_RS20930	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SE95_RS20935	COG0359	binds to the 23S rRNA
SE95_RS20950	COG0305	Participates in initiation and elongation during chromosome replication
SE95_RS20955	COG1733	regulation of RNA biosynthetic process
SE95_RS20975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SE95_RS20995	COG1846	Transcriptional regulator
SE95_RS21030	COG0626	cystathionine gamma-synthase activity
SE95_RS21035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SE95_RS21040	COG1950	PFAM Membrane protein of
SE95_RS21045	COG0662	Cupin 2, conserved barrel domain protein
SE95_RS21065	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SE95_RS21075	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SE95_RS21080	COG1609	Transcriptional regulator
SE95_RS21085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SE95_RS21095	COG1271	oxidase subunit
SE95_RS21100	COG1294	oxidase, subunit
SE95_RS21115	COG0561	phosphatase activity
SE95_RS21125	COG0501	Belongs to the peptidase M48B family
SE95_RS21135	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SE95_RS21150	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SE95_RS21155	COG0789	Transcriptional regulator
SE95_RS21200	COG2807	transmembrane transport
SE95_RS21205	COG2186	Transcriptional regulator
SE95_RS21230	COG0583	DNA-binding transcription factor activity
SE95_RS21250	COG0561	phosphatase activity
SE95_RS21255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SE95_RS21265	COG2837	iron assimilation
SE95_RS21270	COG2372	response to copper ion
SE95_RS21300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SE95_RS21370	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS21380	COG0006	proline dipeptidase activity
SE95_RS21400	COG0653	protein targeting
SE95_RS21415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SE95_RS21430	COG1846	Transcriptional regulator
SE95_RS21435	COG0697	spore germination
SE95_RS21455	COG1960	acyl-CoA dehydrogenase activity
SE95_RS21465	COG1960	acyl-CoA dehydrogenase activity
SE95_RS21475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SE95_RS21485	COG1595	DNA-templated transcription, initiation
SE95_RS21500	COG3437	response regulator, receiver
SE95_RS21520	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS21525	COG0784	Response regulator, receiver
SE95_RS21530	COG5000	phosphorelay sensor kinase activity
SE95_RS21580	COG2249	NAD(P)H dehydrogenase (quinone) activity
SE95_RS21605	COG0745	RESPONSE REGULATOR receiver
SE95_RS21610	COG2205	protein histidine kinase activity
SE95_RS21620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SE95_RS21620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SE95_RS21625	COG0477	Major facilitator Superfamily
SE95_RS21645	COG2353	YceI-like domain
SE95_RS21700	COG1191	sigma factor activity
SE95_RS21705	COG1191	sigma factor activity
SE95_RS21745	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS21750	COG0583	DNA-binding transcription factor activity
SE95_RS21760	COG0590	tRNA wobble adenosine to inosine editing
SE95_RS21770	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SE95_RS21805	COG0523	cobalamin synthesis protein
SE95_RS21815	COG1064	alcohol dehydrogenase
SE95_RS21840	COG2268	Band 7 protein
SE95_RS21905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SE95_RS21910	COG1834	amidinotransferase
SE95_RS21920	COG2188	Transcriptional regulator
SE95_RS21925	COG0477	Major facilitator Superfamily
SE95_RS21935	COG0402	S-adenosylhomocysteine deaminase activity
SE95_RS21955	COG1595	DNA-templated transcription, initiation
SE95_RS21995	COG1132	(ABC) transporter
SE95_RS22025	COG2188	Transcriptional regulator
SE95_RS22050	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SE95_RS22055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SE95_RS22080	COG1595	DNA-templated transcription, initiation
SE95_RS22110	COG0339	signal peptide processing
SE95_RS22115	COG4249	Peptidase C14 caspase catalytic subunit p20
SE95_RS22115	COG2319	Wd-40 repeat
SE95_RS22125	COG1408	metallophosphoesterase
SE95_RS22135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SE95_RS22150	COG0003	Pfam Anion-transporting ATPase
SE95_RS22175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SE95_RS22210	COG2267	carboxylic ester hydrolase activity
SE95_RS22220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SE95_RS22225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SE95_RS22290	COG1111	helicase
SE95_RS22290	COG1205	dead DEAH box helicase
SE95_RS22295	COG1366	Belongs to the anti-sigma-factor antagonist family
SE95_RS22305	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SE95_RS22315	COG2890	protein-(glutamine-N5) methyltransferase activity
SE95_RS22340	COG1754	DNA topoisomerase type I activity
SE95_RS22340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SE95_RS22345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SE95_RS22350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SE95_RS22365	COG0584	glycerophosphoryl diester phosphodiesterase
SE95_RS22370	COG3594	Acyltransferase
SE95_RS22385	COG1349	DNA-binding transcription factor activity
SE95_RS22395	COG1309	transcriptional regulator
SE95_RS22400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SE95_RS22400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SE95_RS22440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SE95_RS22440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SE95_RS22450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SE95_RS22455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SE95_RS22460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SE95_RS22465	COG0254	rRNA binding
SE95_RS22475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SE95_RS22480	COG0640	Transcriptional regulator
SE95_RS22505	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS22510	COG2318	DinB family
SE95_RS22520	COG0076	glutamate decarboxylase activity
SE95_RS22525	COG0655	NAD(P)H dehydrogenase (quinone) activity
SE95_RS22535	COG0789	Transcriptional regulator
SE95_RS22540	COG0393	Putative heavy-metal-binding
SE95_RS22545	COG0586	Pfam SNARE associated Golgi protein
SE95_RS22555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SE95_RS22560	COG2027	D-alanyl-D-alanine carboxypeptidase
SE95_RS22570	COG0037	tRNA processing
SE95_RS22585	COG0302	gtp cyclohydrolase
SE95_RS22610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SE95_RS22615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SE95_RS22625	COG0517	IMP dehydrogenase activity
SE95_RS22625	COG1125	glycine betaine transport
SE95_RS22630	COG1174	glycine betaine transport
SE95_RS22635	COG1174	glycine betaine transport
SE95_RS22640	COG1732	Glycine betaine
SE95_RS22650	COG0649	NAD binding
SE95_RS22660	COG4585	Histidine kinase
SE95_RS22665	COG2197	response regulator
SE95_RS22680	COG0640	Transcriptional regulator
SE95_RS22690	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SE95_RS22700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SE95_RS22705	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SE95_RS22715	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SE95_RS22735	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SE95_RS22765	COG0739	heme binding
SE95_RS22795	COG2205	protein histidine kinase activity
SE95_RS22800	COG0745	RESPONSE REGULATOR receiver
SE95_RS22810	COG1595	DNA-templated transcription, initiation
SE95_RS22815	COG1194	a g-specific adenine glycosylase
SE95_RS22825	COG0671	phosphoesterase, PA-phosphatase related
SE95_RS22845	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SE95_RS22865	COG0248	Ppx GppA phosphatase
SE95_RS22870	COG1082	Xylose isomerase domain protein TIM barrel
SE95_RS22875	COG0129	dihydroxy-acid dehydratase activity
SE95_RS22905	COG1595	DNA-templated transcription, initiation
SE95_RS22915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SE95_RS22920	COG0180	Tryptophanyl-tRNA synthetase
SE95_RS22970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS22975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SE95_RS22985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SE95_RS23000	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS23045	COG0739	heme binding
SE95_RS23045	COG1196	nuclear chromosome segregation
SE95_RS23045	COG0741	lytic transglycosylase activity
SE95_RS23050	COG0671	phosphoesterase, PA-phosphatase related
SE95_RS23055	COG0277	FAD linked oxidase domain protein
SE95_RS23075	COG1937	Protein conserved in bacteria
SE95_RS23085	COG0306	phosphate transporter
SE95_RS23140	COG1595	DNA-templated transcription, initiation
SE95_RS23145	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS23155	COG0754	glutathionylspermidine amidase activity
SE95_RS23160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SE95_RS23165	COG2890	protein-(glutamine-N5) methyltransferase activity
SE95_RS23170	COG0667	Aldo Keto reductase
SE95_RS23190	COG1733	regulation of RNA biosynthetic process
SE95_RS23195	COG0431	NADPH-dependent FMN reductase
SE95_RS23215	COG1490	D-aminoacyl-tRNA deacylase activity
SE95_RS23220	COG0354	folic acid binding
SE95_RS23235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SE95_RS23240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS23245	COG3485	protocatechuate 3,4-dioxygenase
SE95_RS23265	COG2897	thiosulfate sulfurtransferase activity
SE95_RS23300	COG0745	RESPONSE REGULATOR receiver
SE95_RS23305	COG1609	Transcriptional regulator
SE95_RS23310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SE95_RS23315	COG0745	RESPONSE REGULATOR receiver
SE95_RS23320	COG2205	protein histidine kinase activity
SE95_RS23330	COG0737	Belongs to the 5'-nucleotidase family
SE95_RS23335	COG0456	acetyltransferase
SE95_RS23345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SE95_RS23355	COG0494	nUDIX hydrolase
SE95_RS23355	COG0406	alpha-ribazole phosphatase activity
SE95_RS23370	COG0438	transferase activity, transferring glycosyl groups
SE95_RS23385	COG0588	phosphoglycerate mutase activity
SE95_RS23395	COG5002	protein histidine kinase activity
SE95_RS23415	COG1329	Transcriptional regulator
SE95_RS23420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SE95_RS23425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SE95_RS23435	COG0215	cysteine-tRNA ligase activity
SE95_RS23450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SE95_RS23460	COG3842	ATPase activity
SE95_RS23470	COG0582	viral genome integration into host DNA
SE95_RS23540	COG2186	Transcriptional regulator
SE95_RS23600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SE95_RS23620	COG0667	Aldo Keto reductase
SE95_RS23725	COG1228	amidohydrolase
SE95_RS23755	COG3336	cytochrome c oxidase
SE95_RS23760	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SE95_RS23765	COG0463	Glycosyl transferase, family 2
SE95_RS23780	COG1278	Cold shock
SE95_RS23805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SE95_RS23805	COG1263	PTS System
SE95_RS23810	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SE95_RS23855	COG3142	Participates in the control of copper homeostasis
SE95_RS23865	COG3973	AAA domain
SE95_RS23880	COG1061	Type III restriction enzyme res subunit
SE95_RS23895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SE95_RS23900	COG1120	ATPase activity
SE95_RS23905	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS23910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS23925	COG1278	Cold shock
SE95_RS23930	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SE95_RS23935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SE95_RS23990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SE95_RS24000	COG2252	PERMEase
SE95_RS24025	COG0667	Aldo Keto reductase
SE95_RS24050	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SE95_RS24065	COG0277	FAD linked oxidase domain protein
SE95_RS24065	COG0247	lactate metabolic process
SE95_RS24075	COG0583	DNA-binding transcription factor activity
SE95_RS24080	COG5006	permease, DMT superfamily
SE95_RS24095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SE95_RS24110	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS24130	COG0259	pyridoxamine-phosphate oxidase activity
SE95_RS24140	COG4821	SIS domain
SE95_RS24150	COG0596	Alpha beta hydrolase
SE95_RS24150	COG2945	thiolester hydrolase activity
SE95_RS24175	COG1131	(ABC) transporter
SE95_RS24255	COG0515	serine threonine protein kinase
SE95_RS24260	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS24280	COG0519	Catalyzes the synthesis of GMP from XMP
SE95_RS24280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SE95_RS24285	COG2084	Dehydrogenase
SE95_RS24320	COG2815	serine threonine protein kinase
SE95_RS24320	COG0515	serine threonine protein kinase
SE95_RS24330	COG2197	response regulator
SE95_RS24360	COG0739	heme binding
SE95_RS24370	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SE95_RS24385	COG0714	Associated with various cellular activities
SE95_RS24395	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SE95_RS24520	COG0045	succinate-CoA ligase (ADP-forming) activity
SE95_RS24550	COG0138	bifunctional purine biosynthesis protein purh
SE95_RS24565	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SE95_RS24575	COG0039	L-malate dehydrogenase activity
SE95_RS24610	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS24620	COG0517	IMP dehydrogenase activity
SE95_RS24620	COG4175	Glycine betaine
SE95_RS24625	COG4176	ABC-type proline glycine betaine transport system permease component
SE95_RS24650	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SE95_RS24695	COG1295	ribonuclease BN
SE95_RS24705	COG0180	Tryptophanyl-tRNA synthetase
SE95_RS24710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SE95_RS24715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SE95_RS24725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SE95_RS24730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SE95_RS24735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SE95_RS24775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SE95_RS24780	COG1053	succinate dehydrogenase
SE95_RS24790	COG2009	succinate dehydrogenase
SE95_RS24820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SE95_RS24820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SE95_RS24835	COG3265	gluconokinase activity
SE95_RS24870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SE95_RS24880	COG1216	Glycosyl transferase, family 2
SE95_RS24895	COG2089	acid synthase
SE95_RS24905	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SE95_RS24905	COG1473	amidohydrolase
SE95_RS24910	COG1744	ABC transporter substrate-binding protein PnrA-like
SE95_RS24915	COG3845	ABC transporter
SE95_RS24920	COG4603	Belongs to the binding-protein-dependent transport system permease family
SE95_RS24925	COG1079	Belongs to the binding-protein-dependent transport system permease family
SE95_RS24940	COG2814	Major facilitator Superfamily
SE95_RS24945	COG0583	DNA-binding transcription factor activity
SE95_RS24955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SE95_RS24980	COG2205	protein histidine kinase activity
SE95_RS24985	COG0745	RESPONSE REGULATOR receiver
SE95_RS24990	COG1595	DNA-templated transcription, initiation
SE95_RS25005	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS25010	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS25015	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SE95_RS25045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SE95_RS25080	COG4770	biotin carboxylase activity
SE95_RS25095	COG0424	maF-like protein
SE95_RS25105	COG2365	Tyrosine phosphatase family
SE95_RS25110	COG0768	penicillin binding
SE95_RS25120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SE95_RS25130	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SE95_RS25135	COG1024	Enoyl-CoA hydratase
SE95_RS25145	COG2986	histidine ammonia-lyase
SE95_RS25160	COG1376	ErfK ybiS ycfS ynhG family protein
SE95_RS25170	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS25205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SE95_RS25235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SE95_RS25250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SE95_RS25260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SE95_RS25290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SE95_RS25330	COG1331	Highly conserved protein containing a thioredoxin domain
SE95_RS25335	COG0604	alcohol dehydrogenase
SE95_RS25340	COG0154	amidase activity
SE95_RS25345	COG0789	Transcriptional regulator
SE95_RS25360	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SE95_RS25375	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SE95_RS25390	COG1414	Transcriptional regulator
SE95_RS25395	COG0251	oxidation-reduction process
SE95_RS25400	COG2610	gluconate transmembrane transporter activity
SE95_RS25490	COG0667	Aldo Keto reductase
SE95_RS25495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SE95_RS25500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SE95_RS25515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SE95_RS25520	COG0450	alkyl hydroperoxide reductase
SE95_RS25555	COG1136	(ABC) transporter
SE95_RS25570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SE95_RS25595	COG0114	fumarate hydratase activity
SE95_RS25610	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SE95_RS25610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SE95_RS25635	COG0778	Nitroreductase
SE95_RS25640	COG1722	exodeoxyribonuclease VII activity
SE95_RS25645	COG1570	exodeoxyribonuclease VII activity
SE95_RS25655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SE95_RS25670	COG0012	GTP binding
SE95_RS25695	COG0531	amino acid
SE95_RS25720	COG0402	S-adenosylhomocysteine deaminase activity
SE95_RS25730	COG1053	succinate dehydrogenase
SE95_RS25750	COG1217	gtp-binding protein TYPA
SE95_RS25755	COG4166	transmembrane transport
SE95_RS25760	COG0601	transmembrane transport
SE95_RS25765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SE95_RS25770	COG0444	Belongs to the ABC transporter superfamily
SE95_RS25775	COG4608	Belongs to the ABC transporter superfamily
SE95_RS25780	COG4608	Belongs to the ABC transporter superfamily
SE95_RS25785	COG0444	Belongs to the ABC transporter superfamily
SE95_RS25790	COG0601	transmembrane transport
SE95_RS25795	COG4166	transmembrane transport
SE95_RS25800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SE95_RS25815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SE95_RS25830	COG1131	(ABC) transporter
SE95_RS25840	COG4585	Histidine kinase
SE95_RS25845	COG2197	response regulator
SE95_RS25885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SE95_RS25890	COG1611	Belongs to the LOG family
SE95_RS25895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SE95_RS25905	COG0519	Catalyzes the synthesis of GMP from XMP
SE95_RS25910	COG1024	Enoyl-CoA hydratase
SE95_RS25920	COG4122	O-methyltransferase activity
SE95_RS25925	COG1595	DNA-templated transcription, initiation
SE95_RS25935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SE95_RS25940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SE95_RS25975	COG0598	Magnesium transport protein CorA
SE95_RS25985	COG2814	Major facilitator Superfamily
SE95_RS26000	COG2095	MarC family integral membrane protein
SE95_RS26005	COG1432	Conserved Protein
SE95_RS26025	COG2095	MarC family integral membrane protein
SE95_RS26030	COG1432	Conserved Protein
SE95_RS26080	COG4166	transmembrane transport
SE95_RS26150	COG0210	DNA helicase
SE95_RS26155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SE95_RS26195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SE95_RS26240	COG3480	Lon protease (S16) C-terminal proteolytic domain
SE95_RS26250	COG1615	UPF0182 protein
SE95_RS26290	COG0753	catalase activity
SE95_RS26300	COG0483	inositol monophosphate 1-phosphatase activity
SE95_RS26310	COG2076	Multidrug Resistance protein
SE95_RS26315	COG1162	GTPase activity
SE95_RS26320	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SE95_RS26330	COG2135	peptidase activity
SE95_RS26340	COG1595	DNA-templated transcription, initiation
SE95_RS26345	COG5662	AntiSigma factor
SE95_RS26350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SE95_RS26350	COG2199	diguanylate cyclase activity
SE95_RS26365	COG0242	peptide deformylase activity
SE95_RS26370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SE95_RS26375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SE95_RS26405	COG2188	Transcriptional regulator
SE95_RS26410	COG2182	Extracellular solute-binding protein
SE95_RS26415	COG1175	transmembrane transport
SE95_RS26420	COG0395	ABC-type sugar transport system, permease component
SE95_RS26425	COG1472	Belongs to the glycosyl hydrolase 3 family
SE95_RS26430	COG0363	glucosamine-6-phosphate deaminase activity
SE95_RS26435	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS26440	COG1309	transcriptional regulator
SE95_RS26455	COG1597	lipid kinase activity
SE95_RS26490	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SE95_RS26505	COG2066	Belongs to the glutaminase family
SE95_RS26520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SE95_RS26535	COG0477	Major facilitator Superfamily
SE95_RS26540	COG0598	Magnesium transport protein CorA
SE95_RS26545	COG2807	transmembrane transport
SE95_RS26550	COG2186	Transcriptional regulator
SE95_RS26555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SE95_RS26560	COG1993	acr, cog1993
SE95_RS26565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SE95_RS26595	COG4106	trans-aconitate 2-methyltransferase activity
SE95_RS26600	COG1126	abc transporter atp-binding protein
SE95_RS26605	COG0765	amino acid transport
SE95_RS26610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SE95_RS26615	COG0281	malic enzyme
SE95_RS26620	COG0604	alcohol dehydrogenase
SE95_RS26660	COG2205	protein histidine kinase activity
SE95_RS26665	COG0745	RESPONSE REGULATOR receiver
SE95_RS26680	COG1357	PFAM Pentapeptide repeats (8 copies)
SE95_RS26685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SE95_RS26770	COG1119	ATPase activity
SE95_RS26780	COG0768	penicillin binding
SE95_RS26790	COG2124	cytochrome p450
SE95_RS26805	COG0018	arginyl-trna synthetase
SE95_RS26810	COG0019	diaminopimelate decarboxylase activity
SE95_RS26815	COG0460	homoserine dehydrogenase
SE95_RS26820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SE95_RS26825	COG0083	homoserine kinase activity
SE95_RS26840	COG0254	rRNA binding
SE95_RS26845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SE95_RS26850	COG2890	protein-(glutamine-N5) methyltransferase activity
SE95_RS26860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SE95_RS26865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SE95_RS26885	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SE95_RS26890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SE95_RS26895	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SE95_RS26900	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SE95_RS26905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SE95_RS26910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SE95_RS26915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SE95_RS26925	COG2124	cytochrome p450
SE95_RS26930	COG4221	oxidoreductase activity
SE95_RS26930	COG3321	synthase
SE95_RS26930	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS26930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS26940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS26940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SE95_RS26940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS26940	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS26940	COG3321	synthase
SE95_RS26945	COG3321	synthase
SE95_RS26945	COG0300	oxidoreductase activity
SE95_RS26945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS26945	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS26945	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS26960	COG0300	oxidoreductase activity
SE95_RS26960	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS26960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS26960	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS26960	COG3321	synthase
SE95_RS26965	COG3321	synthase
SE95_RS26965	COG4221	oxidoreductase activity
SE95_RS26965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS26965	COG0300	oxidoreductase activity
SE95_RS26970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS26970	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS26970	COG3321	synthase
SE95_RS26970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS26970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SE95_RS26980	COG0534	Mate efflux family protein
SE95_RS26990	COG2124	cytochrome p450
SE95_RS26995	COG2124	cytochrome p450
SE95_RS27010	COG3804	dihydrodipicolinate reductase
SE95_RS27015	COG2197	response regulator
SE95_RS27020	COG4585	Histidine kinase
SE95_RS27035	COG1250	3-hydroxyacyl-CoA dehydrogenase
SE95_RS27050	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SE95_RS27105	COG0183	Belongs to the thiolase family
SE95_RS27165	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SE95_RS27165	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SE95_RS27175	COG0745	RESPONSE REGULATOR receiver
SE95_RS27180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SE95_RS27185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SE95_RS27225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SE95_RS27230	COG0857	belongs to the CobB CobQ family
SE95_RS27230	COG0280	phosphate acetyltransferase
SE95_RS27235	COG0205	6-phosphofructokinase activity
SE95_RS27240	COG0577	efflux transmembrane transporter activity
SE95_RS27240	COG1136	(ABC) transporter
SE95_RS27245	COG0577	efflux transmembrane transporter activity
SE95_RS27245	COG1136	(ABC) transporter
SE95_RS27255	COG4565	transcriptional regulatory protein
SE95_RS27260	COG3290	protein histidine kinase activity
SE95_RS27265	COG1301	dicarboxylic acid transport
SE95_RS27270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SE95_RS27275	COG3281	Trehalose synthase
SE95_RS27280	COG0366	Alpha amylase catalytic
SE95_RS27285	COG0366	Alpha amylase catalytic
SE95_RS27300	COG1132	(ABC) transporter
SE95_RS27305	COG1132	(ABC) transporter
SE95_RS27320	COG1376	ErfK ybiS ycfS ynhG family protein
SE95_RS27340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SE95_RS27340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SE95_RS27345	COG0785	Cytochrome C biogenesis protein
SE95_RS27355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SE95_RS27365	COG0438	transferase activity, transferring glycosyl groups
SE95_RS27370	COG0745	RESPONSE REGULATOR receiver
SE95_RS27395	COG0671	phosphoesterase, PA-phosphatase related
SE95_RS27420	COG1760	l-serine dehydratase
SE95_RS27425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SE95_RS27430	COG0509	glycine decarboxylation via glycine cleavage system
SE95_RS27435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SE95_RS27460	COG0747	negative chemotaxis
SE95_RS27470	COG0444	Belongs to the ABC transporter superfamily
SE95_RS27475	COG4608	Belongs to the ABC transporter superfamily
SE95_RS27485	COG2860	membrane
SE95_RS27505	COG0482	sulfurtransferase activity
SE95_RS27515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SE95_RS27525	COG4221	oxidoreductase activity
SE95_RS27545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SE95_RS27555	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SE95_RS27560	COG0154	amidase activity
SE95_RS27570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SE95_RS27580	COG0667	Aldo Keto reductase
SE95_RS27600	COG3511	phospholipase C
SE95_RS27605	COG2409	Drug exporters of the RND superfamily
SE95_RS27620	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SE95_RS27620	COG1672	PFAM Archaeal ATPase
SE95_RS27630	COG2133	pyrroloquinoline quinone binding
SE95_RS27635	COG0667	Aldo Keto reductase
SE95_RS27645	COG3300	MHYT domain
SE95_RS27645	COG5001	Diguanylate cyclase
SE95_RS27660	COG0440	acetolactate synthase activity
SE95_RS27665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SE95_RS27670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SE95_RS27690	COG3835	regulator
SE95_RS27695	COG0506	proline dehydrogenase activity
SE95_RS27700	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS27710	COG0473	3-isopropylmalate dehydrogenase activity
SE95_RS27715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SE95_RS27725	COG0831	urea catabolic process
SE95_RS27725	COG0832	Belongs to the urease beta subunit family
SE95_RS27730	COG0804	urea catabolic process
SE95_RS27735	COG2957	Belongs to the agmatine deiminase family
SE95_RS27740	COG1309	transcriptional regulator
SE95_RS27745	COG0477	Major facilitator Superfamily
SE95_RS27750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SE95_RS27760	COG5492	domain, Protein
SE95_RS27765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SE95_RS27775	COG2814	Major facilitator Superfamily
SE95_RS27780	COG2376	Dihydroxyacetone kinase
SE95_RS27795	COG2018	Roadblock/LC7 domain
SE95_RS27815	COG2018	Roadblock/LC7 domain
SE95_RS27830	COG0179	Fumarylacetoacetate (FAA) hydrolase
SE95_RS27835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SE95_RS27875	COG1414	Transcriptional regulator
SE95_RS27880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SE95_RS27885	COG0066	3-isopropylmalate dehydratase activity
SE95_RS27895	COG0776	regulation of translation
SE95_RS27915	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SE95_RS27920	COG1181	Belongs to the D-alanine--D-alanine ligase family
SE95_RS27940	COG0351	phosphomethylpyrimidine kinase
SE95_RS27945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SE95_RS27950	COG1461	Dihydroxyacetone kinase
SE95_RS27960	COG0742	ribosomal rna small subunit methyltransferase
SE95_RS27965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SE95_RS27980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SE95_RS27985	COG0571	ribonuclease III activity
SE95_RS27990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SE95_RS28000	COG1254	Belongs to the acylphosphatase family
SE95_RS28015	COG0477	Major facilitator Superfamily
SE95_RS28030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SE95_RS28065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SE95_RS28085	COG0228	four-way junction DNA binding
SE95_RS28090	COG1837	Belongs to the UPF0109 family
SE95_RS28095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SE95_RS28100	COG0336	Belongs to the RNA methyltransferase TrmD family
SE95_RS28105	COG0335	large ribosomal subunit rRNA binding
SE95_RS28120	COG0681	Belongs to the peptidase S26 family
SE95_RS28125	COG0681	Belongs to the peptidase S26 family
SE95_RS28140	COG0792	nuclease activity
SE95_RS28155	COG1191	sigma factor activity
SE95_RS28170	COG0052	Belongs to the universal ribosomal protein uS2 family
SE95_RS28175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SE95_RS28180	COG0528	UMP kinase activity
SE95_RS28185	COG0233	cytoplasmic translational termination
SE95_RS28195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SE95_RS28205	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SE95_RS28210	COG3842	ATPase activity
SE95_RS28215	COG2197	response regulator
SE95_RS28220	COG4585	Histidine kinase
SE95_RS28255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SE95_RS28265	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS28280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SE95_RS28290	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS28300	COG3842	ATPase activity
SE95_RS28305	COG1176	ABC-type spermidine putrescine transport system, permease component I
SE95_RS28310	COG1177	transmembrane transport
SE95_RS28315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SE95_RS28350	COG2508	Transcriptional regulator
SE95_RS28355	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS28365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SE95_RS28370	COG0750	zinc metalloprotease
SE95_RS28375	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SE95_RS28390	COG0442	prolyl-tRNA aminoacylation
SE95_RS28395	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SE95_RS28410	COG0779	Required for maturation of 30S ribosomal subunits
SE95_RS28435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SE95_RS28440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SE95_RS28455	COG0455	bacterial-type flagellum organization
SE95_RS28500	COG1404	Belongs to the peptidase S8 family
SE95_RS28550	COG1674	ftsk spoiiie
SE95_RS28560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SE95_RS28565	COG1185	polyribonucleotide nucleotidyltransferase activity
SE95_RS28570	COG0612	Peptidase, M16
SE95_RS28575	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SE95_RS28595	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SE95_RS28600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SE95_RS28605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SE95_RS28640	COG2770	Histidine kinase
SE95_RS28640	COG2208	phosphoserine phosphatase activity
SE95_RS28645	COG2205	protein histidine kinase activity
SE95_RS28645	COG3437	response regulator, receiver
SE95_RS28645	COG4999	Histidine kinase
SE95_RS28645	COG3850	Histidine kinase
SE95_RS28655	COG1674	ftsk spoiiie
SE95_RS28665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SE95_RS28675	COG1058	Belongs to the CinA family
SE95_RS28675	COG1546	Belongs to the CinA family
SE95_RS28680	COG1396	sequence-specific DNA binding
SE95_RS28685	COG0783	Belongs to the Dps family
SE95_RS28695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SE95_RS28700	COG1201	RNA secondary structure unwinding
SE95_RS28745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SE95_RS28750	COG0640	Transcriptional regulator
SE95_RS28755	COG1316	TRANSCRIPTIONal
SE95_RS28770	COG0628	permease
SE95_RS28785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SE95_RS28800	COG0765	amino acid transport
SE95_RS28805	COG0765	amino acid transport
SE95_RS28810	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SE95_RS28815	COG1126	abc transporter atp-binding protein
SE95_RS28825	COG2205	protein histidine kinase activity
SE95_RS28835	COG0583	DNA-binding transcription factor activity
SE95_RS28845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SE95_RS28860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SE95_RS28870	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SE95_RS28875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SE95_RS28885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SE95_RS28920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SE95_RS28925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SE95_RS28930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SE95_RS28960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SE95_RS28995	COG2186	Transcriptional regulator
SE95_RS29000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SE95_RS29015	COG0187	DNA topoisomerase II activity
SE95_RS29025	COG4585	Histidine kinase
SE95_RS29030	COG2197	response regulator
SE95_RS29045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SE95_RS29050	COG0612	Peptidase, M16
SE95_RS29060	COG0739	heme binding
SE95_RS29070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SE95_RS29090	COG1435	thymidine kinase activity
SE95_RS29125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SE95_RS29130	COG0483	inositol monophosphate 1-phosphatase activity
SE95_RS29135	COG0745	RESPONSE REGULATOR receiver
SE95_RS29140	COG2205	protein histidine kinase activity
SE95_RS29165	COG0756	dUTP diphosphatase activity
SE95_RS29180	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SE95_RS29185	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SE95_RS29190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SE95_RS29230	COG0569	domain protein
SE95_RS29240	COG0531	amino acid
SE95_RS29245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SE95_RS29260	COG1201	RNA secondary structure unwinding
SE95_RS29355	COG3903	Transcriptional regulator
SE95_RS29355	COG3629	intracellular signal transduction
SE95_RS29420	COG0477	Major facilitator Superfamily
SE95_RS29430	COG3424	synthase
SE95_RS29460	COG1799	cell septum assembly
SE95_RS29490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SE95_RS29495	COG2235	arginine
SE95_RS29500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SE95_RS29510	COG1024	Enoyl-CoA hydratase
SE95_RS29540	COG0546	phosphoglycolate phosphatase activity
SE95_RS29555	COG1960	acyl-CoA dehydrogenase activity
SE95_RS29565	COG1960	acyl-CoA dehydrogenase activity
SE95_RS29570	COG1024	Enoyl-CoA hydratase
SE95_RS29585	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SE95_RS29610	COG2175	clavaminate synthase activity
SE95_RS29615	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS29665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SE95_RS29670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SE95_RS29685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SE95_RS29690	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS29740	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SE95_RS29830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SE95_RS29850	COG0137	argininosuccinate synthase activity
SE95_RS29855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SE95_RS29875	COG1653	transport
SE95_RS29880	COG1175	transmembrane transport
SE95_RS29885	COG0395	ABC-type sugar transport system, permease component
SE95_RS29890	COG1940	carbohydrate kinase activity
SE95_RS29895	COG4213	ABC transporter substrate-binding protein
SE95_RS29905	COG4214	carbohydrate transport
SE95_RS29910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SE95_RS29915	COG0531	amino acid
SE95_RS29925	COG1250	3-hydroxyacyl-CoA dehydrogenase
SE95_RS29925	COG1024	Enoyl-CoA hydratase
SE95_RS29930	COG0183	Belongs to the thiolase family
SE95_RS29935	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SE95_RS29950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SE95_RS29955	COG0446	pyridine nucleotide-disulphide oxidoreductase
SE95_RS29965	COG0183	Belongs to the thiolase family
SE95_RS29970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SE95_RS29975	COG0446	pyridine nucleotide-disulphide oxidoreductase
SE95_RS29985	COG0183	Belongs to the thiolase family
SE95_RS29995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SE95_RS30000	COG3253	May function as heme-dependent peroxidase
SE95_RS30025	COG1280	lysine exporter protein (LysE YggA)
SE95_RS30035	COG1116	anion transmembrane transporter activity
SE95_RS30070	COG1136	(ABC) transporter
SE95_RS30070	COG0577	efflux transmembrane transporter activity
SE95_RS30080	COG4585	Histidine kinase
SE95_RS30085	COG2197	response regulator
SE95_RS30090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SE95_RS30095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SE95_RS30110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SE95_RS30120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SE95_RS30125	COG0693	protein deglycase activity
SE95_RS30130	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SE95_RS30200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SE95_RS30205	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SE95_RS30225	COG0529	Catalyzes the synthesis of activated sulfate
SE95_RS30230	COG0175	sulfate reduction
SE95_RS30240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SE95_RS30265	COG1960	acyl-CoA dehydrogenase activity
SE95_RS30275	COG1414	Transcriptional regulator
SE95_RS30280	COG3485	protocatechuate 3,4-dioxygenase
SE95_RS30330	COG2080	2 iron, 2 sulfur cluster binding
SE95_RS30335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SE95_RS30340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SE95_RS30350	COG3511	phospholipase C
SE95_RS30355	COG0667	Aldo Keto reductase
SE95_RS30365	COG1376	ErfK ybiS ycfS ynhG family protein
SE95_RS30390	COG1716	ATPase activity
SE95_RS30390	COG1131	(ABC) transporter
SE95_RS30390	COG0842	Transport permease protein
SE95_RS30440	COG3290	protein histidine kinase activity
SE95_RS30445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SE95_RS30445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SE95_RS30450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SE95_RS30465	COG0640	Transcriptional regulator
SE95_RS30470	COG0789	Transcriptional regulator
SE95_RS30475	COG0789	Transcriptional regulator
SE95_RS30485	COG1162	GTPase activity
SE95_RS30500	COG0028	Belongs to the TPP enzyme family
SE95_RS30520	COG1802	Transcriptional regulator
SE95_RS30535	COG3835	regulator
SE95_RS30550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SE95_RS30580	COG4552	Acetyltransferase involved in intracellular survival and related
SE95_RS30595	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS30680	COG2315	Protein conserved in bacteria
SE95_RS30695	COG0753	catalase activity
SE95_RS30700	COG0028	Belongs to the TPP enzyme family
SE95_RS30705	COG2084	Dehydrogenase
SE95_RS30710	COG3622	Belongs to the hyi family
SE95_RS30730	COG2351	hydroxyisourate hydrolase activity
SE95_RS30740	COG2233	PERMEase
SE95_RS30750	COG2233	PERMEase
SE95_RS30770	COG1288	antiporter activity
SE95_RS30780	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SE95_RS30800	COG1414	Transcriptional regulator
SE95_RS30810	COG1953	Uracil, thiamine, allantoin
SE95_RS30815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SE95_RS30820	COG4266	Belongs to the allantoicase family
SE95_RS30855	COG0800	Aldolase
SE95_RS30865	COG0583	DNA-binding transcription factor activity
SE95_RS30875	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS30880	COG2188	Transcriptional regulator
SE95_RS30890	COG1172	Belongs to the binding-protein-dependent transport system permease family
SE95_RS30900	COG1940	carbohydrate kinase activity
SE95_RS30965	COG0667	Aldo Keto reductase
SE95_RS30985	COG3547	Transposase (IS116 IS110 IS902 family)
SE95_RS31000	COG1857	crispr-associated protein
SE95_RS31080	COG1280	lysine exporter protein (LysE YggA)
SE95_RS31185	COG1302	Protein conserved in bacteria
SE95_RS31220	COG0009	L-threonylcarbamoyladenylate synthase
SE95_RS31225	COG0288	reversible hydration of carbon dioxide
SE95_RS31230	COG0202	RNA polymerase activity
SE95_RS31245	COG2255	four-way junction helicase activity
SE95_RS31300	COG0148	phosphopyruvate hydratase activity
SE95_RS31335	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SE95_RS31340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SE95_RS31385	COG0148	phosphopyruvate hydratase activity
SE95_RS31395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SE95_RS31420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SE95_RS31425	COG1993	acr, cog1993
SE95_RS31430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SE95_RS31435	COG0671	phosphoesterase, PA-phosphatase related
SE95_RS31530	COG0159	tryptophan synthase activity
SE95_RS31615	COG0714	Associated with various cellular activities
SE95_RS31655	COG1475	DNA binding
SE95_RS31755	COG1181	Belongs to the D-alanine--D-alanine ligase family
SE95_RS31790	COG1278	Cold shock
SE95_RS31910	COG0456	acetyltransferase
SE95_RS31995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SE95_RS32025	COG2226	methyltransferase
SE95_RS32035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SE95_RS32040	COG0435	Glutathione S-transferase
SE95_RS32055	COG2409	Drug exporters of the RND superfamily
SE95_RS32060	COG0387	Pfam Sodium calcium exchanger
SE95_RS32070	COG0405	Gamma-glutamyltransferase
SE95_RS32080	COG1335	isochorismatase
SE95_RS32085	COG0477	Major facilitator Superfamily
SE95_RS32100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SE95_RS32120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SE95_RS32125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS32150	COG0095	Lipoate-protein ligase
SE95_RS32155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SE95_RS32170	COG0483	inositol monophosphate 1-phosphatase activity
SE95_RS32195	COG1309	transcriptional regulator
SE95_RS32210	COG0494	nUDIX hydrolase
SE95_RS32215	COG1929	Belongs to the glycerate kinase type-1 family
SE95_RS32225	COG0688	phosphatidylethanolamine metabolic process
SE95_RS32230	COG1960	acyl-CoA dehydrogenase activity
SE95_RS32240	COG2301	Belongs to the HpcH HpaI aldolase family
SE95_RS32245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SE95_RS32245	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SE95_RS32260	COG1250	3-hydroxyacyl-CoA dehydrogenase
SE95_RS32280	COG0789	Transcriptional regulator
SE95_RS32310	COG0366	Alpha amylase catalytic
SE95_RS32320	COG2362	D-Aminopeptidase
SE95_RS32325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SE95_RS32340	COG2124	cytochrome p450
SE95_RS32355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SE95_RS32375	COG0010	Belongs to the arginase family
SE95_RS32380	COG0457	Tetratricopeptide repeat
SE95_RS32400	COG1597	lipid kinase activity
SE95_RS32425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SE95_RS32435	COG0531	amino acid
SE95_RS32450	COG2154	pterin-4-alpha-carbinolamine dehydratase
SE95_RS32470	COG2890	protein-(glutamine-N5) methyltransferase activity
SE95_RS32495	COG0656	L-ascorbic acid biosynthetic process
SE95_RS32505	COG0583	DNA-binding transcription factor activity
SE95_RS32530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SE95_RS32540	COG0287	Prephenate dehydrogenase
SE95_RS32540	COG1605	Chorismate mutase
SE95_RS32560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SE95_RS32570	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS32600	COG1132	(ABC) transporter
SE95_RS32625	COG2197	response regulator
SE95_RS32665	COG0577	efflux transmembrane transporter activity
SE95_RS32665	COG1136	(ABC) transporter
SE95_RS32670	COG0577	efflux transmembrane transporter activity
SE95_RS32670	COG1136	(ABC) transporter
SE95_RS32685	COG0745	RESPONSE REGULATOR receiver
SE95_RS32690	COG2205	protein histidine kinase activity
SE95_RS32705	COG0702	epimerase
SE95_RS32710	COG0477	Major facilitator Superfamily
SE95_RS32720	COG0745	RESPONSE REGULATOR receiver
SE95_RS32745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SE95_RS32770	COG0477	Major facilitator Superfamily
SE95_RS32780	COG0431	NADPH-dependent FMN reductase
SE95_RS32785	COG0667	Aldo Keto reductase
SE95_RS32835	COG2124	cytochrome p450
SE95_RS32840	COG1819	glycosyl
SE95_RS32850	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SE95_RS32875	COG2192	nodulation
SE95_RS32905	COG5002	protein histidine kinase activity
SE95_RS32920	COG0697	spore germination
SE95_RS32940	COG1687	branched-chain amino acid
SE95_RS32950	COG1522	sequence-specific DNA binding
SE95_RS32970	COG1063	alcohol dehydrogenase
SE95_RS32985	COG4585	Histidine kinase
SE95_RS32990	COG2197	response regulator
SE95_RS32995	COG2340	Cysteine-rich secretory protein family
SE95_RS33005	COG0640	Transcriptional regulator
SE95_RS33015	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS33015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS33015	COG0300	oxidoreductase activity
SE95_RS33015	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS33015	COG3321	synthase
SE95_RS33025	COG3903	Transcriptional regulator
SE95_RS33025	COG3629	intracellular signal transduction
SE95_RS33030	COG0720	synthase
SE95_RS33040	COG0302	gtp cyclohydrolase
SE95_RS33045	COG0517	IMP dehydrogenase activity
SE95_RS33045	COG0516	GMP reductase activity
SE95_RS33050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SE95_RS33055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SE95_RS33060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SE95_RS33070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SE95_RS33090	COG0647	UMP catabolic process
SE95_RS33120	COG0717	Belongs to the dCTP deaminase family
SE95_RS33125	COG0475	glutathione-regulated potassium exporter activity
SE95_RS33135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SE95_RS33140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SE95_RS33150	COG1834	amidinotransferase
SE95_RS33180	COG0583	DNA-binding transcription factor activity
SE95_RS33185	COG1846	Transcriptional regulator
SE95_RS33205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SE95_RS33210	COG1846	Transcriptional regulator
SE95_RS33220	COG1309	transcriptional regulator
SE95_RS33245	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SE95_RS33255	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS33270	COG1136	(ABC) transporter
SE95_RS33330	COG2205	protein histidine kinase activity
SE95_RS33335	COG0745	RESPONSE REGULATOR receiver
SE95_RS33360	COG3226	Transcriptional regulator
SE95_RS33370	COG1846	Transcriptional regulator
SE95_RS33380	COG1309	transcriptional regulator
SE95_RS33390	COG1309	transcriptional regulator
SE95_RS33395	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS33400	COG1349	DNA-binding transcription factor activity
SE95_RS33410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SE95_RS33415	COG2814	Major facilitator Superfamily
SE95_RS33420	COG2801	Transposase and inactivated derivatives
SE95_RS33420	COG3415	Transposase
SE95_RS33430	COG1515	deoxyribonuclease V activity
SE95_RS33435	COG3268	Saccharopine dehydrogenase
SE95_RS33445	COG1285	pathogenesis
SE95_RS33450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SE95_RS33460	COG1960	acyl-CoA dehydrogenase activity
SE95_RS33465	COG0183	Belongs to the thiolase family
SE95_RS33470	COG1250	3-hydroxyacyl-CoA dehydrogenase
SE95_RS33470	COG1024	Enoyl-CoA hydratase
SE95_RS33485	COG1113	amino acid transport
SE95_RS33495	COG3568	Endonuclease Exonuclease Phosphatase
SE95_RS33540	COG2936	dipeptidyl-peptidase activity
SE95_RS33570	COG2183	response to ionizing radiation
SE95_RS33580	COG4977	sequence-specific DNA binding
SE95_RS33615	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SE95_RS33650	COG1134	teichoic acid transport
SE95_RS33655	COG1562	ergosterol biosynthetic process
SE95_RS33665	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SE95_RS33675	COG1657	PFAM Prenyltransferase squalene oxidase
SE95_RS33695	COG2365	Tyrosine phosphatase family
SE95_RS33700	COG2755	lipolytic protein G-D-S-L family
SE95_RS33760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SE95_RS33780	COG2018	Roadblock/LC7 domain
SE95_RS33805	COG1228	amidohydrolase
SE95_RS33810	COG2267	carboxylic ester hydrolase activity
SE95_RS33840	COG2124	cytochrome p450
SE95_RS33845	COG1686	Belongs to the peptidase S11 family
SE95_RS33875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SE95_RS33890	COG1250	3-hydroxyacyl-CoA dehydrogenase
SE95_RS33895	COG3246	L-lysine catabolic process to acetate
SE95_RS33910	COG0174	glutamine synthetase
SE95_RS33920	COG0477	Major facilitator Superfamily
SE95_RS33925	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS33950	COG1024	Enoyl-CoA hydratase
SE95_RS33955	COG1960	acyl-CoA dehydrogenase activity
SE95_RS33965	COG0477	Major facilitator Superfamily
SE95_RS33980	COG2378	regulation of single-species biofilm formation
SE95_RS33990	COG1652	LysM domain
SE95_RS33995	COG1113	amino acid transport
SE95_RS34000	COG2706	6-phosphogluconolactonase activity
SE95_RS34035	COG0698	ribose 5-phosphate isomerase
SE95_RS34040	COG0149	triose-phosphate isomerase activity
SE95_RS34095	COG3537	Alpha-1,2-mannosidase
SE95_RS34110	COG0531	amino acid
SE95_RS34115	COG3360	Dodecin
SE95_RS34165	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SE95_RS34170	COG0121	glutamine amidotransferase
SE95_RS34175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SE95_RS34180	COG3572	ergothioneine biosynthetic process
SE95_RS34215	COG1960	acyl-CoA dehydrogenase activity
SE95_RS34220	COG1960	acyl-CoA dehydrogenase activity
SE95_RS34250	COG0601	transmembrane transport
SE95_RS34255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SE95_RS34260	COG0444	Belongs to the ABC transporter superfamily
SE95_RS34275	COG1349	DNA-binding transcription factor activity
SE95_RS34280	COG2814	Major facilitator Superfamily
SE95_RS34290	COG1070	Carbohydrate kinase
SE95_RS34295	COG0588	phosphoglycerate mutase activity
SE95_RS34300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SE95_RS34305	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SE95_RS34305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SE95_RS34330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SE95_RS34330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SE95_RS34335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SE95_RS34340	COG1070	Carbohydrate kinase
SE95_RS34345	COG3458	cephalosporin-C deacetylase activity
SE95_RS34360	COG0765	amino acid transport
SE95_RS34370	COG2040	homocysteine
SE95_RS34385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SE95_RS34430	COG2018	Roadblock/LC7 domain
SE95_RS34450	COG1946	Acyl-CoA thioesterase
SE95_RS34465	COG1132	(ABC) transporter
SE95_RS34470	COG1132	(ABC) transporter
SE95_RS34480	COG1301	dicarboxylic acid transport
SE95_RS34505	COG1132	(ABC) transporter
SE95_RS34510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SE95_RS34515	COG1556	Lactate utilization protein
SE95_RS34535	COG0247	lactate metabolic process
SE95_RS34540	COG0477	Major facilitator Superfamily
SE95_RS34550	COG0492	ferredoxin-NADP+ reductase activity
SE95_RS34565	COG1116	anion transmembrane transporter activity
SE95_RS34570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SE95_RS34575	COG0432	Pfam Uncharacterised protein family UPF0047
SE95_RS34580	COG2124	cytochrome p450
SE95_RS34595	COG2304	oxidoreductase activity
SE95_RS34615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SE95_RS34620	COG3467	pyridoxamine 5'-phosphate
SE95_RS34645	COG1309	transcriptional regulator
SE95_RS34670	COG2124	cytochrome p450
SE95_RS34675	COG1309	transcriptional regulator
SE95_RS34715	COG4213	ABC transporter substrate-binding protein
SE95_RS34720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SE95_RS34755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SE95_RS34760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SE95_RS34780	COG1595	DNA-templated transcription, initiation
SE95_RS34790	COG2706	6-phosphogluconolactonase activity
SE95_RS34815	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SE95_RS34825	COG1902	pentaerythritol trinitrate reductase activity
SE95_RS34860	COG2197	response regulator
SE95_RS34865	COG0366	Alpha amylase catalytic
SE95_RS34870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SE95_RS34885	COG2345	Transcriptional regulator
SE95_RS34915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SE95_RS34930	COG1285	pathogenesis
SE95_RS34970	COG0477	Major facilitator Superfamily
SE95_RS34975	COG1957	nucleoside hydrolase
SE95_RS34980	COG1609	Transcriptional regulator
SE95_RS35000	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SE95_RS35020	COG1796	DNA polymerase
SE95_RS35020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SE95_RS35045	COG0488	(ABC) transporter
SE95_RS35050	COG0488	(ABC) transporter
SE95_RS35065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SE95_RS35075	COG2197	response regulator
SE95_RS35080	COG4585	Histidine kinase
SE95_RS35090	COG0596	Alpha beta hydrolase
SE95_RS35095	COG0805	protein transport
SE95_RS35165	COG2205	protein histidine kinase activity
SE95_RS35170	COG0745	RESPONSE REGULATOR receiver
SE95_RS35180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SE95_RS35180	COG3291	Pkd domain containing protein
SE95_RS35205	COG0515	serine threonine protein kinase
SE95_RS35205	COG2815	serine threonine protein kinase
SE95_RS35240	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS35260	COG1309	transcriptional regulator
SE95_RS35270	COG1960	acyl-CoA dehydrogenase activity
SE95_RS35275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SE95_RS35300	COG1228	amidohydrolase
SE95_RS35310	COG0463	Glycosyl transferase, family 2
SE95_RS35325	COG2270	Major facilitator Superfamily
SE95_RS35355	COG3012	SEC-C Motif Domain Protein
SE95_RS35365	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SE95_RS35370	COG1793	dna ligase
SE95_RS35370	COG3285	dna ligase
SE95_RS35375	COG1686	Belongs to the peptidase S11 family
SE95_RS35380	COG1278	Cold shock
SE95_RS35415	COG0395	ABC-type sugar transport system, permease component
SE95_RS35420	COG1175	transmembrane transport
SE95_RS35430	COG1609	Transcriptional regulator
SE95_RS35445	COG4585	Histidine kinase
SE95_RS35450	COG2197	response regulator
SE95_RS35455	COG0739	heme binding
SE95_RS35485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SE95_RS35495	COG1846	Transcriptional regulator
SE95_RS35500	COG1764	response to oxidative stress
SE95_RS35540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SE95_RS35610	COG2124	cytochrome p450
SE95_RS35615	COG1250	3-hydroxyacyl-CoA dehydrogenase
SE95_RS35615	COG1024	Enoyl-CoA hydratase
SE95_RS35625	COG0110	maltose O-acetyltransferase activity
SE95_RS35640	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SE95_RS35650	COG1832	CoA-binding protein
SE95_RS35665	COG1739	Uncharacterized protein family UPF0029
SE95_RS35670	COG0531	amino acid
SE95_RS35680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SE95_RS35715	COG0584	glycerophosphoryl diester phosphodiesterase
SE95_RS35720	COG0420	3'-5' exonuclease activity
SE95_RS35725	COG0419	ATPase involved in DNA repair
SE95_RS35730	COG1522	sequence-specific DNA binding
SE95_RS35750	COG0346	lactoylglutathione lyase activity
SE95_RS35760	COG2188	Transcriptional regulator
SE95_RS35765	COG1940	carbohydrate kinase activity
SE95_RS35780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SE95_RS35795	COG1309	transcriptional regulator
SE95_RS35815	COG0456	acetyltransferase
SE95_RS35830	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS35850	COG1802	Transcriptional regulator
SE95_RS35855	COG0697	spore germination
SE95_RS35865	COG0583	DNA-binding transcription factor activity
SE95_RS35880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SE95_RS35885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SE95_RS35890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SE95_RS35915	COG0740	serine-type endopeptidase activity
SE95_RS35940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SE95_RS36050	COG0831	urea catabolic process
SE95_RS36055	COG0832	Belongs to the urease beta subunit family
SE95_RS36060	COG0804	urea catabolic process
SE95_RS36070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SE95_RS36075	COG0829	nickel cation binding
SE95_RS36115	COG0205	6-phosphofructokinase activity
SE95_RS36120	COG3442	glutamine amidotransferase
SE95_RS36130	COG0242	peptide deformylase activity
SE95_RS36140	COG1960	acyl-CoA dehydrogenase activity
SE95_RS36200	COG1215	transferase activity, transferring glycosyl groups
SE95_RS36210	COG0745	RESPONSE REGULATOR receiver
SE95_RS36215	COG2205	protein histidine kinase activity
SE95_RS36220	COG3960	tartronate-semialdehyde synthase activity
SE95_RS36225	COG3622	Belongs to the hyi family
SE95_RS36230	COG2084	Dehydrogenase
SE95_RS36235	COG2205	protein histidine kinase activity
SE95_RS36245	COG2124	cytochrome p450
SE95_RS36265	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS36280	COG0477	Major facilitator Superfamily
SE95_RS36295	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SE95_RS36325	COG0375	protein maturation
SE95_RS36330	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SE95_RS36335	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SE95_RS36340	COG0298	carbon dioxide binding
SE95_RS36350	COG0309	Hydrogenase expression formation protein (HypE)
SE95_RS36375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SE95_RS36385	COG2837	iron assimilation
SE95_RS36400	COG0640	Transcriptional regulator
SE95_RS36405	COG0531	amino acid
SE95_RS36420	COG1793	dna ligase
SE95_RS36435	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS36455	COG3290	protein histidine kinase activity
SE95_RS36460	COG1349	DNA-binding transcription factor activity
SE95_RS36465	COG3395	kinase activity
SE95_RS36470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SE95_RS36515	COG3328	transposase activity
SE95_RS36525	COG2814	Major facilitator Superfamily
SE95_RS36545	COG3118	belongs to the thioredoxin family
SE95_RS36575	COG2233	PERMEase
SE95_RS36600	COG0657	acetylesterase activity
SE95_RS36610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS36620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SE95_RS36625	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS36630	COG1960	acyl-CoA dehydrogenase activity
SE95_RS36635	COG1960	acyl-CoA dehydrogenase activity
SE95_RS36640	COG1960	acyl-CoA dehydrogenase activity
SE95_RS36645	COG1024	Enoyl-CoA hydratase
SE95_RS36650	COG1960	acyl-CoA dehydrogenase activity
SE95_RS36660	COG1309	transcriptional regulator
SE95_RS36665	COG0183	Belongs to the thiolase family
SE95_RS36690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SE95_RS36695	COG2365	Tyrosine phosphatase family
SE95_RS36715	COG1024	Enoyl-CoA hydratase
SE95_RS36725	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS36730	COG3971	2-oxopent-4-enoate hydratase activity
SE95_RS36765	COG1960	acyl-CoA dehydrogenase activity
SE95_RS36770	COG2267	carboxylic ester hydrolase activity
SE95_RS36780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SE95_RS36785	COG2030	dehydratase
SE95_RS36790	COG1053	succinate dehydrogenase
SE95_RS36810	COG2945	thiolester hydrolase activity
SE95_RS36810	COG0596	Alpha beta hydrolase
SE95_RS36825	COG3511	phospholipase C
SE95_RS36860	COG1181	Belongs to the D-alanine--D-alanine ligase family
SE95_RS36865	COG0477	Major facilitator Superfamily
SE95_RS36870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS36880	COG0151	Belongs to the GarS family
SE95_RS36890	COG1509	lysine 2,3-aminomutase activity
SE95_RS36895	COG0436	Aminotransferase
SE95_RS36910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS36965	COG2261	transglycosylase associated protein
SE95_RS36985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SE95_RS36990	COG1316	TRANSCRIPTIONal
SE95_RS37000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SE95_RS37005	COG0640	Transcriptional regulator
SE95_RS37055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SE95_RS37060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SE95_RS37080	COG2837	iron assimilation
SE95_RS37105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SE95_RS37110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SE95_RS37115	COG1116	anion transmembrane transporter activity
SE95_RS37120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SE95_RS37130	COG0596	Alpha beta hydrolase
SE95_RS37145	COG0596	Alpha beta hydrolase
SE95_RS37160	COG2124	cytochrome p450
SE95_RS37210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SE95_RS37215	COG1120	ATPase activity
SE95_RS37245	COG0515	serine threonine protein kinase
SE95_RS37255	COG1132	(ABC) transporter
SE95_RS37260	COG1132	(ABC) transporter
SE95_RS37265	COG2197	response regulator
SE95_RS37285	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SE95_RS37285	COG0515	serine threonine protein kinase
SE95_RS37295	COG0515	serine threonine protein kinase
SE95_RS37295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SE95_RS37310	COG0583	DNA-binding transcription factor activity
SE95_RS37330	COG1595	DNA-templated transcription, initiation
SE95_RS37380	COG0167	dihydroorotate dehydrogenase activity
SE95_RS37390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SE95_RS37395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SE95_RS37420	COG1021	2,3-dihydroxybenzoate-AMP ligase
SE95_RS37425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS37440	COG0488	(ABC) transporter
SE95_RS37455	COG1309	transcriptional regulator
SE95_RS37460	COG0154	amidase activity
SE95_RS37465	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS37465	COG0604	alcohol dehydrogenase
SE95_RS37465	COG3321	synthase
SE95_RS37475	COG1132	(ABC) transporter
SE95_RS37490	COG3226	Transcriptional regulator
SE95_RS37495	COG0154	amidase activity
SE95_RS37505	COG1733	regulation of RNA biosynthetic process
SE95_RS37530	COG0477	Major facilitator Superfamily
SE95_RS37560	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
SE95_RS37575	COG1309	transcriptional regulator
SE95_RS37585	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SE95_RS37595	COG1410	methionine synthase
SE95_RS37595	COG0646	methionine synthase
SE95_RS37600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SE95_RS37605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SE95_RS37610	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS37620	COG2197	response regulator
SE95_RS37625	COG0066	3-isopropylmalate dehydratase activity
SE95_RS37630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SE95_RS37635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SE95_RS37640	COG0473	3-isopropylmalate dehydrogenase activity
SE95_RS37645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SE95_RS37670	COG0477	Major facilitator Superfamily
SE95_RS37685	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SE95_RS37690	COG1692	metallophosphoesterase
SE95_RS37695	COG0475	glutathione-regulated potassium exporter activity
SE95_RS37700	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS37705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SE95_RS37710	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SE95_RS37715	COG0129	dihydroxy-acid dehydratase activity
SE95_RS37745	COG3903	Transcriptional regulator
SE95_RS37745	COG3629	intracellular signal transduction
SE95_RS37770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SE95_RS37780	COG2267	carboxylic ester hydrolase activity
SE95_RS37790	COG1063	alcohol dehydrogenase
SE95_RS37835	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS37865	COG3634	alkyl hydroperoxide reductase activity
SE95_RS37875	COG0702	epimerase
SE95_RS37885	COG2045	Belongs to the ComB family
SE95_RS37900	COG1960	acyl-CoA dehydrogenase activity
SE95_RS37910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SE95_RS37915	COG0583	DNA-binding transcription factor activity
SE95_RS37940	COG2268	Band 7 protein
SE95_RS37945	COG1585	Membrane protein implicated in regulation of membrane protease activity
SE95_RS37955	COG0672	)-iron permease
SE95_RS38050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SE95_RS38065	COG2249	NAD(P)H dehydrogenase (quinone) activity
SE95_RS38070	COG0640	Transcriptional regulator
SE95_RS38080	COG2197	response regulator
SE95_RS38085	COG4585	Histidine kinase
SE95_RS38095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SE95_RS38100	COG0443	Heat shock 70 kDa protein
SE95_RS38135	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SE95_RS38135	COG0517	IMP dehydrogenase activity
SE95_RS38175	COG0640	Transcriptional regulator
SE95_RS38180	COG0463	Glycosyl transferase, family 2
SE95_RS38185	COG0488	(ABC) transporter
SE95_RS38195	COG2423	ornithine cyclodeaminase activity
SE95_RS38210	COG0367	asparagine synthase
SE95_RS38220	COG2423	ornithine cyclodeaminase activity
SE95_RS38225	COG3469	chitinase activity
SE95_RS38235	COG0009	L-threonylcarbamoyladenylate synthase
SE95_RS38255	COG2378	regulation of single-species biofilm formation
SE95_RS38260	COG1070	Carbohydrate kinase
SE95_RS38265	COG1063	alcohol dehydrogenase
SE95_RS38275	COG2124	cytochrome p450
SE95_RS38290	COG0702	epimerase
SE95_RS38300	COG1191	sigma factor activity
SE95_RS38355	COG2132	Multicopper oxidase
SE95_RS38375	COG2226	methyltransferase
SE95_RS38400	COG1175	transmembrane transport
SE95_RS38405	COG0395	ABC-type sugar transport system, permease component
SE95_RS38425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SE95_RS38470	COG0477	Major facilitator Superfamily
SE95_RS38560	COG2205	protein histidine kinase activity
SE95_RS38635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SE95_RS38650	COG0747	negative chemotaxis
SE95_RS38670	COG1464	Belongs to the NlpA lipoprotein family
SE95_RS38680	COG2011	ABC-type metal ion transport system permease component
SE95_RS38705	COG0504	CTP synthase activity
SE95_RS38730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SE95_RS38760	COG3046	protein related to deoxyribodipyrimidine photolyase
SE95_RS38770	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS38775	COG1556	Lactate utilization protein
SE95_RS38780	COG1139	Iron-sulfur cluster binding protein
SE95_RS38785	COG0247	lactate metabolic process
SE95_RS38800	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS38830	COG2957	Belongs to the agmatine deiminase family
SE95_RS38840	COG4608	Belongs to the ABC transporter superfamily
SE95_RS38845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SE95_RS38855	COG0747	negative chemotaxis
SE95_RS38860	COG2957	Belongs to the agmatine deiminase family
SE95_RS38880	COG2957	Belongs to the agmatine deiminase family
SE95_RS38885	COG2957	Belongs to the agmatine deiminase family
SE95_RS38890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SE95_RS38960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SE95_RS38965	COG0697	spore germination
SE95_RS39005	COG3938	Belongs to the proline racemase family
SE95_RS39040	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SE95_RS39080	COG3321	synthase
SE95_RS39080	COG0604	alcohol dehydrogenase
SE95_RS39080	COG0604	alcohol dehydrogenase
SE95_RS39080	COG3321	synthase
SE95_RS39105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SE95_RS39115	COG0604	alcohol dehydrogenase
SE95_RS39115	COG3321	synthase
SE95_RS39125	COG0604	alcohol dehydrogenase
SE95_RS39125	COG3321	synthase
SE95_RS39140	COG2197	response regulator
SE95_RS39165	COG1473	amidohydrolase
SE95_RS39180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SE95_RS39195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SE95_RS39210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SE95_RS39240	COG1012	belongs to the aldehyde dehydrogenase family
SE95_RS39245	COG1063	alcohol dehydrogenase
SE95_RS39250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SE95_RS39260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SE95_RS39280	COG1140	nitrate reductase beta subunit
SE95_RS39345	COG4948	Mandelate Racemase Muconate Lactonizing
SE95_RS39435	COG2345	Transcriptional regulator
SE95_RS39450	COG0673	inositol 2-dehydrogenase activity
SE95_RS39520	COG0702	epimerase
SE95_RS39540	COG1132	(ABC) transporter
SE95_RS39600	COG0745	RESPONSE REGULATOR receiver
SE95_RS39605	COG5002	protein histidine kinase activity
SE95_RS39665	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SE95_RS39670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SE95_RS39685	COG0318	PFAM AMP-dependent synthetase and ligase
SE95_RS39695	COG1250	3-hydroxyacyl-CoA dehydrogenase
SE95_RS39725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SE95_RS39725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SE95_RS39745	COG0596	Alpha beta hydrolase
SE95_RS39750	COG1309	transcriptional regulator
SE95_RS39760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SE95_RS39765	COG2815	serine threonine protein kinase
SE95_RS39765	COG0515	serine threonine protein kinase
SE95_RS39780	COG3795	YCII-related domain
SE95_RS39785	COG4941	Belongs to the sigma-70 factor family
SE95_RS39790	COG1021	2,3-dihydroxybenzoate-AMP ligase
SE95_RS39795	COG2272	Belongs to the type-B carboxylesterase lipase family
SE95_RS39805	COG2814	Major facilitator Superfamily
SE95_RS39810	COG3979	chitinase
SE95_RS39815	COG2226	methyltransferase
SE95_RS39930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SE95_RS39945	COG2197	response regulator
SE95_RS39955	COG1136	(ABC) transporter
SE95_RS39955	COG0577	efflux transmembrane transporter activity
SE95_RS39975	COG3321	synthase
SE95_RS39975	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS39975	COG0604	alcohol dehydrogenase
SE95_RS39985	COG0666	response to abiotic stimulus
SE95_RS40000	COG2208	phosphoserine phosphatase activity
SE95_RS40000	COG2770	Histidine kinase
SE95_RS40070	COG1028	Short-chain dehydrogenase reductase Sdr
SE95_RS40095	COG1733	regulation of RNA biosynthetic process
SE95_RS40100	COG0702	epimerase
SE95_RS40125	COG0300	oxidoreductase activity
SE95_RS40165	COG0431	NADPH-dependent FMN reductase
SE95_RS40175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SE95_RS40215	COG1053	succinate dehydrogenase
SE95_RS40270	COG1309	transcriptional regulator
SE95_RS40340	COG4977	sequence-specific DNA binding
SE95_RS40425	COG1132	(ABC) transporter
SE95_RS40490	COG2963	transposase activity
SE95_RS40505	COG3409	Peptidoglycan-binding domain 1 protein
SE95_RS40570	COG1309	transcriptional regulator
SE95_RS40580	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD